A myomagnetic measurement device based on cobalt-based amorphous wire

By developing a ring-shaped myomagnetic measurement device based on nano-cobalt-based amorphous wires and PDMS packaging, combined with the fundamental-wave fluxgate principle and deep learning algorithm, the problems of high cost, large size and harsh working conditions of existing myomagnetic measurement devices have been solved, and low-cost, small-volume, room-temperature myomagnetic measurement has been achieved, promoting its widespread application in the fields of human-computer interface and medical diagnosis.

CN116746934BActive Publication Date: 2025-09-26DALIAN UNIV OF TECH
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Patent Information

Application Number
CN202310505809.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-05-08
Publication Date
2025-09-26
Estimated Expiration
2043-05-08

AI Technical Summary

Technical Problem

Existing myomagnetic measurement devices are expensive, bulky, and have harsh working conditions, making it difficult to achieve close-range measurement and widespread application.

Method used

A ring-shaped myomagnetic measurement device was designed using nano-cobalt-based amorphous wire as the magnetic core, combined with PDMS flexible material packaging and the working principle of fundamental-wave fluxgate. It included a sensor probe, an excitation module, and a detection module. PDMS was used to protect the cobalt-based amorphous wire, and deep learning algorithms were used to optimize data processing.

Benefits of technology

It realizes low-cost, small-volume, room-temperature myomagnetic measurement, has excellent biocompatibility, is suitable for wearable design, and promotes the application of myomagnetic measurement in the fields of human-computer interface and medical diagnosis.

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Abstract

The present invention discloses a myomagnetic measurement device based on a cobalt-based amorphous wire, comprising a sensor probe, an excitation module, and a detection module. The fluxgate probe is composed of a cobalt-based amorphous wire surrounded by a flexible polydimethylsiloxane (PDMS) material and a coil. The excitation module is connected to the cobalt-based amorphous wire to provide an AC current drive with a DC bias. The detection module is connected to the coil to achieve myomagnetic measurement by detecting the fundamental amplitude of the coil-induced signal. Compared with existing myomagnetic measurement devices based on SQUID sensors, the myomagnetic measurement device has the advantages of small size, low cost, no need for magnetic shielding, and can operate at room temperature. The myomagnetic measurement device in the present invention is expected to achieve miniaturization and wearable design, promoting the widespread application of myomagnetic measurement in the fields of human-machine interface and medical diagnosis.
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Description

Technical Field

[0001] The present invention relates to the field of biomagnetic field detection, in particular to a myomagnetic measuring device based on cobalt-based amorphous wires. Background Art

[0002] Magnetomyography is a method of detecting skeletal muscle activity by detecting the magnetic field generated by intramuscular current. It has great application value in the fields of myopathy medical diagnosis, intelligent human-computer interface, etc.

[0003] The magnetic field signal generated by the muscle when it vibrates is similar to the Earth's magnetic field (50 T and above) is extremely weak. Currently, superconducting quantum interference devices (SQUID sensors) are mostly used to measure myomagnetic energy. Since SQUID sensors require a huge magnetic shielding room and a low-temperature superconducting environment during operation, they cannot measure myomagnetic energy at close range. At the same time, their high cost is not conducive to the medical application of myomagnetic energy measurement.

[0004] The basic principle of fluxgate technology is to utilize the property of soft magnetic materials that are easy to magnetically saturate. Through a periodic AC excitation signal, the magnetic core reaches or nearly reaches a periodic magnetic saturation state, and the magnetic saturation frequency is twice the frequency of the excitation signal. When there is no external magnetic field, the two adjacent magnetic saturation waveforms are exactly the same. When the magnetic field generated by the external magnetic field or the external current passes through the magnetic core, it is equivalent to adding a bias to the magnetic field in the magnetic core, changing the depth of the two adjacent magnetic saturation states (or changing their arrival time), thereby measuring the external magnetic field or current.

[0005] In recent years, fluxgate sensors, which utilize nano-cobalt-based amorphous wires as their cores and employ DC bias excitation technology and fundamental wave detection principles, have seen significant development. PDMS, a flexible polymer with a polydimethylsiloxane backbone, exhibits excellent biocompatibility and high- and low-temperature resistance. It remains flexible and does not harden at low temperatures, nor deform or soften at high temperatures. It also exhibits good dielectric properties and a certain degree of breathability. Using PDMS can further leverage the advantages of cobalt-based amorphous coils. By combining the collected myomagnetic signals with deep learning algorithms, the data can be optimized and processed more accurately and efficiently, ultimately establishing a health monitoring mechanism. These sensors, with their high sensitivity, low cost, and compact size, are expected to become a new generation of myomagnetic detection technology, promoting its widespread application in human-machine interfaces and medical diagnostics. Summary of the Invention

[0006] The purpose of the present invention is to address the problems of high cost, large size, and harsh working conditions in existing myomagnetic measurement devices. Based on nano-cobalt-based amorphous linear materials and combined with the working principle of fundamental wave fluxgate, a ring-shaped myomagnetic measurement device with simple structure, low cost and small size is provided.

[0007] The present invention is achieved through the following technical solutions:

[0008] A myomagnetic measuring device based on cobalt-based amorphous wire comprises a sensor probe, an excitation module and a detection module.

[0009] The sensor probe consists of a cobalt-based amorphous wire and a coil surrounded by a flexible PDMS material. Cobalt-based amorphous wire offers superior performance but is relatively fragile. To enhance the accuracy of myomagnetic measurements, it is encapsulated in PDMS. The coil is spirally wound around the PDMS-encased cobalt-based amorphous wire. The first section, from the upper opening to about one-third of the upper semicircle, features denser winding. The second section, from about one-third of the upper semicircle to about one-third of the lower semicircle, features less dense winding. The ratio of coil counts in the first to second sections is 3:1. The third section, from the lower opening to about one-third of the lower semicircle, maintains the same winding density as the first section. The coil is made of enameled copper wire.

[0010] The excitation module is connected to a low-pass filter circuit via a temperature-compensated crystal oscillator through a frequency divider to generate a sinusoidal signal, which is then connected to a current drive circuit at the same time as a voltage reference to generate a DC bias signal. The current drive circuit is connected to a cobalt-based amorphous wire surrounded by PDMS flexible material to provide current excitation for the sensor probe.

[0011] The detection module is connected to the data acquisition circuit through the amplifier circuit, bandpass filter circuit, phase-sensitive detection circuit, and low-pass filter circuit. The coil is connected to the detection module through the amplifier circuit, and the frequency divider is connected to the phase-sensitive detection circuit to provide a reference signal for phase-sensitive detection.

[0012] Beneficial effects of the present invention:

[0013] The proposed myomagnetic measurement device is based on nano-cobalt-based amorphous linear materials and utilizes a flexible PDMS material for external protection, further enhancing measurement stability. Incorporating the fundamental fluxgate principle, it enables close-range detection of myomagnetic activity. Compared to existing myomagnetic measurement devices based on SQUID sensors, this device offers advantages such as compact size, low cost, lack of magnetic shielding, and room-temperature operation. These advantages contribute to its superior biocompatibility and potential for miniaturization and wearable design, promoting the widespread application of myomagnetic measurement in human-machine interfaces and medical diagnostics. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 11 is a schematic structural diagram of the myomagnetic measuring device of the present invention;

[0015] Figure 2 It is a structural diagram of a data processing unit of the present invention;

[0016] Figure 3 Schematic diagram of the double-layer gradient sensor probe of the present invention.

[0017] In the figure, 1 is the sensor probe, 2 is the excitation module, 3 is the detection module, 4 is the data processing unit, and 5 is the double-layer gradient structure unit. 11 is a cobalt-based amorphous wire surrounded by PDMS flexible material, 12 is the coil, 21 is a temperature-compensated crystal oscillator, 22 is a frequency divider, 23 is a low-pass filter circuit, 24 is a voltage reference, 25 is a current drive circuit, 31 is an amplifier circuit, 32 is a band-pass filter circuit, 33 is a phase-sensitive detection circuit, 34 is a low-pass filter circuit, 35 is a data acquisition circuit, 41 is a digital-to-analog conversion unit, 42 is a feature extraction unit, 43 is a neural network processing unit, 51 is the upper myomagnetic measurement ring, and 52 is the lower myomagnetic measurement ring. DETAILED DESCRIPTION

[0018] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments:

[0019] A myomagnetic measurement device based on nano-cobalt-based amorphous wires comprises a sensor probe 1, an excitation module 2 and a detection module 3.

[0020] like Figure 1As shown, a sensor probe 1 is placed in a ring-like configuration on skeletal muscle for myomagnetic measurement. The sensor probe 1 consists of a cobalt-based amorphous wire 11, encased in a flexible PDMS material, and a coil 12. Coil 12 is helically wound around the PDMS-encased cobalt-based amorphous wire 11, with the winding being denser near the opening (where muscle density is higher) and sparser farther from the opening (where muscle density is lower). Coil 12 is made of enameled copper wire. The excitation module 2 consists of a temperature-compensated crystal oscillator 21 connected to a low-pass filter circuit 23 via a frequency divider 22 to generate a sinusoidal signal. This signal is then connected to a voltage reference 24 and a current drive circuit 25 to generate a DC bias signal. The current drive circuit 25 is connected to the cobalt-based amorphous wire 11 to provide current excitation for the sensor probe 1. The detection module 3 consists of an amplifier circuit 31 connected to a data acquisition circuit 35 via a bandpass filter circuit 32, a phase-sensitive detector circuit 33, and a low-pass filter circuit 34. Coil 12 is connected to detection module 3 via amplifier circuit 31. Frequency divider 22 is connected to phase-sensitive detection circuit 33 to provide a reference signal for phase-sensitive detection. To increase measurement accuracy, two identical sensor probes—an upper myomagnetic measurement ring 51 and a lower myomagnetic measurement ring 52—are used simultaneously. These are placed approximately 5 cm above and below the muscle being measured for myomagnetic measurement. The results from these two sensor probes are processed by the same excitation module 2 and detection module 3, and the two sets of data are compared and processed, doubling measurement accuracy.

[0021] Example 1

[0022] The diameter of the cobalt-based amorphous wire (11) surrounded by the PDMS flexible material in the sensor probe (1) is 100 μm. A current is passed through the wire for annealing. The annealing current has an amplitude of 400 mA, a frequency of 0.1 Hz, a square wave waveform, and an annealing time of 30 minutes. The coil (12) in the sensor probe (1) is made of 0.05 mm copper enameled wire and has 1200 turns. The excitation signal generated by the excitation unit (2) has a frequency of 100 kHz, an amplitude of 40 mA, and a DC bias of 50 mA. When the coil (12) detects the myomagnetic field signal, the tiny myomagnetic signal is amplified by the amplifier circuit (31), and then the signal is denoised and smoothed by the bandpass filter circuit (32), the phase-sensitive detection circuit (33), and the low-pass filter circuit (34). The signal is then input to the analog-to-digital converter (41) through the data acquisition port (35) for feature extraction, and output through the fully connected layer of the neural network (43) to obtain the accuracy of the measured myomagnetic signal.

[0023] Example 2

[0024] The diameter of the cobalt-based amorphous wire (51) in the upper layer of the sensor probe group (5) surrounded by the PDMS flexible material is 30 μm, and the diameter of the cobalt-based amorphous wire 52 in the lower layer of the PDMS flexible material is 30 μm. A current is applied to each of them for annealing. The annealing current has an amplitude of 150 mA, a frequency of 0.1 Hz, a square wave waveform, and an annealing time of 20 minutes. The coil 12 in the sensor probe group (5) is made of 0.05 mm copper enameled wire and has 1200 turns. The excitation signal generated by the excitation unit (2) has a frequency of 100 kHz, an amplitude of 30 mA, and a DC bias of 40 mA. Two identical excitation units (2) are used to act on (51) and (52) simultaneously. When the coil (12) detects the myomagnetic field signal, the tiny myomagnetic signal is amplified by the amplifier circuit (31), and then the signal is denoised and smoothed by the bandpass filter circuit (32), the phase-sensitive detection circuit (33), and the low-pass filter circuit (34). The two sets of data are weighted averaged to obtain a more accurate myomagnetic signal. The new myomagnetic signal is then input into the analog-to-digital converter (41) through the data acquisition port (35) for feature extraction. After being output by the fully connected layer of the neural network (43), the accuracy of the measured myomagnetic signal can be obtained.

[0025] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made on the basis of the present invention are within the scope of protection of the present invention.

Claims

1. A myomagnetic measuring device based on cobalt-based amorphous wire, characterized in that: It includes a sensor probe (1), an excitation module (2) and a detection module (3); The sensor probe (1) is composed of a cobalt-based amorphous wire (11) surrounded by a PDMS flexible material and a coil (12); the coil (12) is spirally wound on the cobalt-based amorphous wire surrounded by the PDMS, the first part is from the upper opening to one-third of the entire upper semicircle arc, the second part is from one-third of the upper semicircle arc to one-third of the lower semicircle arc, the ratio of the number of coils in the first part to the second part is 3:1, and the third part is from the lower opening to about one-third of the entire lower semicircle arc, and the winding density is the same as that of the first part; The excitation module (2) is connected to a low-pass filter circuit (23) through a temperature-compensated crystal oscillator (21) via a frequency divider (22) to generate a sinusoidal signal, which is then connected to a current drive circuit (25) at the same time as a voltage reference (24) to generate a DC bias signal. The current drive circuit (25) is connected to a cobalt-based amorphous wire (11) surrounded by a PDMS flexible material to provide current excitation for the sensor probe (1); The detection module (3) is connected to the data acquisition (35) via the amplifier circuit (31) through the bandpass filter circuit (32), the phase-sensitive detection circuit (33), and the low-pass filter circuit (34); the coil (12) is connected to the detection module (3) via the amplifier circuit (31), and the frequency divider (22) is connected to the phase-sensitive detection circuit (33) to provide a reference signal for the phase-sensitive detection.

2. A myomagnetic measuring device based on cobalt-based amorphous wire according to claim 1, characterized in that: The material of the coil (12) is copper enameled copper wire.

3. A myomagnetic measuring device based on cobalt-based amorphous wire according to claim 1 or 2, characterized in that: The coil (12) is made of 0.05 mm copper enameled wire and has 1200 turns.

4. A myomagnetic measuring device based on cobalt-based amorphous wire according to claim 1 or 2, characterized in that: The annealing current amplitude of the cobalt-based amorphous wire (11) cannot be less than 100 mA and cannot exceed 500 mA, the frequency is 0.1 Hz, and the waveform is a square wave.

5. The myomagnetic measuring device based on cobalt-based amorphous wire according to claim 3, characterized in that: The annealing current amplitude of the cobalt-based amorphous wire (11) cannot be less than 100 mA and cannot exceed 500 mA, the frequency is 0.1 Hz, and the waveform is a square wave.

6. A method for using a myomagnetic measuring device based on a cobalt-based amorphous wire according to any one of claims 1 to 5, characterized in that: Two identical sensor probes (1) are used simultaneously, serving as an upper myomagnetic measurement ring (51) and a lower myomagnetic measurement ring (52), respectively, and are placed 5 cm above and below the measured muscle to perform myomagnetic measurement. After the measurement results of the two sensor probes are processed by the same excitation module (2) and detection module (3), the two sets of data are compared and processed, thereby doubling the measurement accuracy.

7. The method for using the myomagnetic measuring device based on cobalt-based amorphous wire according to claim 6, characterized in that: The myomagnetic signal collected by the sensor probe (1) is converted into a digital signal by a digital-to-analog conversion unit (41). After being processed by a feature extraction unit (42) and a neural network processing unit (43), the result of the fully connected layer is output to obtain the accuracy of the measurement result.

Citation Information

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