Sample centrifuge device

Abstract

This invention discloses a sample centrifugation device, comprising: a turntable with circumferentially arranged mounting grooves along its edge; a motor for driving the turntable to rotate; a receiving component for detachably mounting test tubes on the receiving component, each mounting groove pivotally connected to the receiving component to allow the receiving component to tilt radially; the receiving component having two axially extending ends and an axially extending outer peripheral surface; a synchronization disk disposed below the turntable and configured to move axially relative to the turntable; the synchronization disk having multiple hollow portions corresponding one-to-one with the receiving components, each hollow portion being fitted onto the receiving component, and the edge of the hollow portion slidingly engaging with the outer peripheral surface of the receiving component, so that the synchronization disk drives all receiving components to pivot synchronously through axial movement; and an adjustment actuation mechanism for driving the synchronization disk to move axially.

Description

Technical Field

[0001] This invention relates to the field of biochemical detection equipment technology, and more particularly to a sample centrifugation device. Background Technology

[0002] As is well known, centrifuges are commonly used in biochemical (e.g., food, medical) testing processes to separate samples in test tubes into supernatant and precipitate for centrifugation. Existing centrifuges typically include a horizontally rotating disc and multiple slots evenly distributed around the disc, allowing numerous test tubes to be placed in these slots. Rotation of the disc causes all test tubes to revolve, performing centrifugation. Therefore, centrifuges can simultaneously centrifuge samples from multiple test tubes, offering advantages in efficiency and labor savings. However, for different types of samples or different centrifugation requirements, test tubes are not always required to be vertical; in many cases, tilting is necessary. Therefore, existing technology configures each slot to pivotally connect to the disc, allowing adjustment of the test tube's tilt angle.

[0003] However, under normal circumstances, the same centrifugation conditions need to be applied to the same batch of samples placed on the turntable. That is, all test tubes usually need to be tilted at the same angle. For the centrifuges mentioned above in the prior art, the angle of the slots needs to be adjusted one by one to make all the slots angle the same.

[0004] In addition, as is well known, before centrifuging the sample in the test tube, the test tube needs to be swung to ensure that the sample is fully mixed and dissolved. However, existing centrifuges do not have the function of driving the test tube to swung frequently and can only be operated manually. Summary of the Invention

[0005] To address the aforementioned technical problems in the prior art, embodiments of the present invention provide a sample centrifugation device.

[0006] To solve the above-mentioned technical problems, the technical solution adopted in the embodiments of the present invention is as follows:

[0007] A sample centrifugation device, comprising:

[0008] The turntable has mounting grooves arranged circumferentially along its edge;

[0009] An electric motor is used to drive the turntable to rotate;

[0010] A receiving component, on which test tubes are detachably disposed, wherein each mounting slot is pivotally connected to the receiving component so that the receiving component can be tilted radially; the receiving component has two axially extending ends and an axially extending outer peripheral surface;

[0011] A synchronizing disk is disposed below the turntable and configured to move axially relative to the turntable; the synchronizing disk has a plurality of hollowed-out portions corresponding one-to-one with the receiving components, each hollowed-out portion is fitted onto the receiving component, and the edge of the hollowed-out portion slides in cooperation with the outer peripheral surface of the receiving component, so that the synchronizing disk drives all receiving components to pivot synchronously through axial movement.

[0012] Adjust the actuation mechanism, which is used to drive the synchronous disk to move axially.

[0013] Preferably, the outer peripheral surface of the receiving component is cylindrical; an insertion hole is provided at the upper end of the receiving component along its axial direction, and the test tube is used to be inserted into the insertion hole; wherein:

[0014] Pins are formed on both sides of the outer peripheral surface of the receiving component near the upper end; ear plates are formed on both sides of the receiving component, and the ear plates on both sides define the mounting groove.

[0015] The ear plate is provided with a pin hole, and the pin of the receiving component is inserted into the pin hole accordingly;

[0016] A torsion spring is installed at the pin hole, and the two ends of the torsion spring are respectively connected to the ear plate and the pin to provide the receiving component with an elastic torque in the radially inward direction toward the turntable.

[0017] Preferably, the outer peripheral surface of the receiving component is provided with a wedge-shaped guide extending along the axial direction in the region facing the outer edge of the hollow portion, so that the receiving component can be adjusted to a vertical state by sliding the hollow portion of the synchronization disc to a position close to the lower end of the receiving component.

[0018] Preferably, the adjustment actuation mechanism includes an actuation component; the actuation component includes:

[0019] An electromagnetic actuation component is disposed below the synchronization disk, the electromagnetic actuation component including an electromagnetic coil facing the synchronization disk;

[0020] A permanent magnet ring is disposed at the bottom of the synchronization disk to form a magnetic force with the electromagnetic actuation component; wherein:

[0021] The electromagnetic coil of the electromagnetic actuator is periodically energized to create a periodic magnetic force with the permanent magnet ring, thereby driving the synchronous disk to move axially.

[0022] Preferably, the adjustment actuation mechanism further includes an adjustment component; the adjustment component includes:

[0023] Inner sleeve, which is formed in the central region of the upper part of the turntable;

[0024] A force-applying sleeve is fitted outside the inner sleeve and can move along the axial direction of the inner sleeve. The sidewall of the force-applying sleeve is divided into multiple force-applying strips by multiple notches. A through groove is opened on the turntable corresponding to the force-applying strips.

[0025] The pressure nut is sleeved on the inner sleeve and located above the force-applying sleeve. By screwing the pressure nut, the force-applying sleeve is driven to move axially downward, so that the force-applying strip passes through the through groove and pushes downward against the synchronization disc.

[0026] Preferably, a spring is provided between the inner sleeve and the force-applying sleeve, the spring being used to apply an upward elastic force to the force-applying sleeve.

[0027] Preferably, the outer circumference of the inner sleeve is provided with an external thread and an axially extending plum blossom guide rail; the force-applying sleeve cooperates with the inner sleeve through the plum blossom guide rail, and the pressure nut cooperates with the inner sleeve thread through the external thread.

[0028] Preferably, a rubber bushing is provided on the wall of the insertion hole of the receiving component.

[0029] Preferably, the motor is located below the turntable, and the motor drives the turntable through a rotating shaft; an axially extending plum blossom guide rail is arranged on the outer periphery of the rotating shaft, and the synchronous disc is sleeved on the rotating shaft and moves along the axial direction of the rotating shaft by cooperating with the plum blossom guide rail.

[0030] Preferably, the sample centrifugation device further includes a cover; the cover has tubing arranged inside, each corresponding to a receiving component, the tubing forming a bundle at its distal end, and when the cover is fastened above the turntable, the proximal end of the tubing extends into the test tube of the receiving component.

[0031] Compared with the prior art, the beneficial effects of the sample centrifugation device provided by the embodiments of the present invention are:

[0032] 1. The tilt angle of the test tube can be adjusted synchronously through the sliding cooperation between the synchronous disk and the receiving component.

[0033] 2. By driving the synchronous disk to reciprocate, the test tubes can be swung in the same and synchronous manner before centrifugation.

[0034] 3. The test tube can be rotated to a vertical position by sliding contact between the synchronous disc and the wedge-shaped guide on the receiving component, so as to facilitate the synchronous injection of the fluid required for the test. Attached Figure Description

[0035] Figure 1 A front view of a sample centrifugation apparatus provided for an embodiment of the present invention.

[0036] Figure 2A top view of a sample centrifugation apparatus provided for an embodiment of the present invention.

[0037] Figure 3 for Figure 2 A magnified view of part A.

[0038] Figure 4 A view of the sample centrifugation apparatus in use as provided in an embodiment of the present invention (with the test tube twisted to a vertical position).

[0039] Figure 5 A view of the sample centrifugation apparatus in use (with the test tube in a swinging state) provided for an embodiment of the present invention.

[0040] Figure 6 A view of the sample centrifugation apparatus in use as provided in an embodiment of the present invention (with the test tube twisted to a vertical position).

[0041] In the picture:

[0042] 10-Turntable; 11-Mounting slot; 12-Ear plate; 13-Through slot; 20-Synchronizing disc; 21-Hollowed part; 30-Accommodating component; 31-Insertion hole; 32-Wedge-shaped guide part; 33-Pin shaft; 34-Torsion spring; 35-Rubber bushing; 40-Adjusting actuation mechanism; 41-Actuation component; 411-Electromagnetic coil; 412-Frame; 413-Permanent magnet ring; 42-Adjusting component; 421-Inner sleeve; 422-Force application sleeve; 4221-Force application strip; 423-Pressure nut; 424-Spring; 50-Motor; 51-Rotating shaft; 60-Test platform; 70-Closure cover; 81-Pipeline; 82-Pipe bundle. Detailed Implementation

[0043] To enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.

[0044] An embodiment of the present invention discloses a sample centrifugation device, which is applied in the sample detection process and is used to centrifuge the sample.

[0045] like Figures 1 to 3 As shown, the centrifuge device includes: a turntable 10, a motor 50, a housing component 30, a synchronization disc 20, an adjustment actuation mechanism 40, and a cover 70.

[0046] A turntable 10 is positioned above a test platform 60, and a motor 50 is mounted below the test platform 60. The motor 50 is connected to the turntable 10 via a rotating shaft 51 to drive the turntable 10 to rotate. The edge of the turntable 10 is provided with multiple mounting slots 11. Specifically, each mounting slot 11 is defined by a lug 12 positioned opposite to the turntable 10. A clearance space is provided between two lugs 12 to prevent interference between the receiving component 30 and the turntable 10 during rotation.

[0047] The receiving component 30 is configured in a cylindrical shape similar to a test tube. Therefore, the receiving component 30 has an upper end and a lower end in the axial direction. An insertion hole 31 is opened from the upper end. A test tube containing a sample is inserted into the insertion hole. Preferably, a rubber bushing 35 is provided on the wall of the insertion hole 31 to dampen the test tube inserted into the insertion hole 31 and prevent the test tube from moving around.

[0048] Pins 33 are formed on both sides of the outer periphery of the receiving component 30 near the upper end. The pins 33 are inserted into the pin holes of the ear plate 12. A torsion spring 34 is installed in each pin hole. One end of the torsion spring 34 is connected to the pin 33 and the other end is connected to the ear plate 12. Thus, the torsion spring 34 is used to provide torque to the receiving component 30 in the direction toward the turntable 10.

[0049] A wedge-shaped guide portion 32 is formed on the outer side of the outer peripheral surface of the receiving component 30, and the height of the wedge-shaped guide portion 32 gradually increases from the upper end to the lower end.

[0050] Synchronous disk 20 is located below turntable 10. The middle part of synchronous disk 20 is sleeved on rotating shaft 51, and axially extending spline guide rail is arranged on rotating shaft 51. Synchronous disk 20 cooperates with spline guide rail so that synchronous disk 20 can slide axially relative to rotating shaft 51 while rotation is restricted.

[0051] The edge of the synchronization disk 20 has multiple hollow portions 21 corresponding to the receiving components 30. The outer edge of each hollow portion 21 is configured as an arc-shaped edge that can mate with the outer peripheral surface of the receiving component 30. The hollow portions 21 are fitted onto the outer peripheral surface of the receiving component 30. When the synchronization disk 20 is in a high position, i.e., close to the turntable 10, the edge of the hollow portion 21 contacts the outer peripheral surface of the receiving component 30 near the upper end. At this time, under the action of the torsion spring 34, the receiving component 30 and the test tube are in the maximum tilt state. When the synchronization disk 20 is moved down, the hollow portion 21 slides into contact with the outer peripheral surface of the receiving component 30, thereby causing the receiving component 30 and the test tube to twist in the vertical direction. Figure 4 As shown, by sliding to the end of the wedge-shaped guide 32, the receiving component 30 and the test tube are finally twisted to a vertical state. Therefore, the axial movement of the synchronous disk 20 can change the tilt angle of the receiving component 30, thereby changing the tilt angle of the test tube.

[0052] The adjustment actuation mechanism 40 includes an actuation component 41 and an adjustment component 42. The actuation component 41 includes an electromagnetic actuation element and a permanent magnet ring 413. The electromagnetic actuation element includes a frame 412 and an electromagnetic coil 411 installed within the frame 412. The frame 412 is mounted on the optical shaft below the stepped portion of the rotating shaft 51 via bearings, and the frame 412 is simultaneously fixed to the test platform 60. The electromagnetic coil 411 is installed in the frame 412, and the generated magnetic force is directed towards the synchronous disk 20. A permanent magnet is embedded in the bottom of the synchronous disk 20 and is positioned opposite to the electromagnetic coil 411. By periodically energizing the electromagnetic coil 411, the electromagnetic coil 411 generates a magnetic force on the permanent magnet ring 413. Specifically, as shown... Figure 5 As shown, by alternately passing forward and reverse currents to the electromagnetic coil 411, the electromagnetic coil 411 applies magnetic attraction and magnetic repulsion to the permanent magnet, thereby causing the synchronous disk 20 to reciprocate axially, and through cooperation with the torsion spring 34 of the accommodating component 30, the accommodating component 30 and the test tube to oscillate radially.

[0053] The adjusting assembly 42 includes an inner sleeve 421, a force-applying sleeve 422, and a pressure nut 423. The inner sleeve 421 is formed in the central area of ​​the upper part of the turntable 10. The force-applying sleeve 422 is sleeved on the inner sleeve 421 and can move axially along the inner sleeve 421. The side wall of the force-applying sleeve 422 is divided into multiple force-applying strips 4221 by multiple notches. A through groove 13 is opened on the turntable 10 corresponding to the force-applying strips 4221. The pressure nut 423 is sleeved on the inner sleeve 421 and located above the force-applying sleeve 422. The outer periphery of the inner sleeve 421 is provided with external threads and axially extending plum blossom guide rails. The force-applying sleeve 422 cooperates with the inner sleeve 421 through the plum blossom guide rails, and the pressure nut 423 is threadedly engaged with the inner sleeve 421 through external threads. A spring 424 is provided between the inner sleeve 421 and the force-applying sleeve 422. The spring 424 is used to apply an upward elastic force to the force-applying sleeve 422. Thus, by screwing the nut 423, the force-applying sleeve 422 is driven to move axially downward, causing the force-applying strip 4221 to pass through the through groove 13 and push downward against the timing disc 20.

[0054] When it is necessary to adjust the angle of the housing 30 and the test tube, the pressure nut 423 is turned to drive the force application sleeve 422 to move axially. The position of the synchronous disk 20 is adjusted by the cooperation of the force application strip 4221 and the torsion spring 34, so that the housing 30 and the test tube are adjusted to the required angle.

[0055] In addition, by screwing the nut 423, the synchronous disk 20 is pushed to a position that causes the receiving component 30 and the test tube to be rotated to a vertical position, so as to facilitate the uniform injection and aspiration of samples into the test tube.

[0056] like Figure 6As shown, the inside of the cover 70 is arranged with tubes 81 corresponding to the receiving component 30. The distal ends of the tubes 81 form tube bundles 82. When the cover 70 is fastened above the turntable 10, the proximal ends of the tubes 81 extend into the test tubes of the receiving component 30. These tubes 81 can be used to inject reagents or liquids into the test tubes, to extract supernatant from the test tubes, and to fill the test tubes with auxiliary gases such as nitrogen.

[0057] The advantages of the centrifuge device provided by this invention are:

[0058] 1. The tilt angle of the test tube can be adjusted synchronously through the sliding engagement of the synchronization disk 20 and the receiving component 30.

[0059] 2. By driving the synchronous disk 20 to reciprocate, the test tubes can be swung in the same and synchronous manner before centrifugation.

[0060] 3. The test tube can be rotated to a vertical position by slidingly engaging the synchronous disc 20 with the wedge-shaped guide 32 on the receiving component 30, so as to synchronously inject the fluid required for the test.

[0061] The above embodiments are merely exemplary embodiments of the present invention and are not intended to limit the present invention. The scope of protection of the present invention is defined by the claims. Those skilled in the art can make various modifications or equivalent substitutions to the present invention within its spirit and scope of protection, and such modifications or equivalent substitutions should also be considered to fall within the scope of protection of the present invention.

Claims

1. A sample centrifugation device, characterized in that, include: The turntable has mounting grooves arranged circumferentially along its edge; An electric motor is used to drive the turntable to rotate; A receiving component, on which test tubes are detachably disposed, wherein each mounting slot is pivotally connected to the receiving component so that the receiving component can be tilted radially; the receiving component has two axially extending ends and an axially extending outer peripheral surface; A synchronizing disk is disposed below the turntable and configured to move axially relative to the turntable; the synchronizing disk has a plurality of hollowed-out portions corresponding one-to-one with the receiving components, each hollowed-out portion is fitted onto the receiving component, and the edge of the hollowed-out portion slides in cooperation with the outer peripheral surface of the receiving component, so that the synchronizing disk drives all receiving components to pivot synchronously through axial movement. Adjustable actuation mechanism, which is used to drive the synchronous disk to move axially; The outer peripheral surface of the receiving component is cylindrical; an insertion hole is provided at the upper end of the receiving component along its axial direction, and the test tube is used to be inserted into the insertion hole; wherein: Pins are formed on both sides of the outer peripheral surface of the receiving component near the upper end; ear plates are formed on both sides of the receiving component, and the ear plates on both sides define the mounting groove. The ear plate is provided with a pin hole, and the pin of the receiving component is inserted into the pin hole accordingly; A torsion spring is installed at the pin hole, and the two ends of the torsion spring are respectively connected to the ear plate and the pin to provide the receiving component with an elastic torque in the radially inward direction toward the turntable. The outer peripheral surface of the receiving component is provided with a wedge-shaped guide extending along the axial direction in the area facing the outer edge of the hollow part. The receiving component is adjusted to a vertical state by sliding the hollow part of the synchronization disk to a position close to the lower end of the receiving component.

2. The sample centrifugation device according to claim 1, characterized in that, The adjustment actuation mechanism includes an actuation component; the actuation component includes: An electromagnetic actuation component is disposed below the synchronization disk, the electromagnetic actuation component including an electromagnetic coil facing the synchronization disk; A permanent magnet ring is disposed at the bottom of the synchronization disk to form a magnetic force with the electromagnetic actuation component; wherein: The electromagnetic coil of the electromagnetic actuator is periodically energized to create a periodic magnetic force with the permanent magnet ring, thereby driving the synchronous disk to move axially.

3. The sample centrifugation device according to claim 2, characterized in that, The adjustment actuation mechanism further includes an adjustment component; the adjustment component includes: Inner sleeve, which is formed in the central region of the upper part of the turntable; A force-applying sleeve is fitted outside the inner sleeve and can move along the axial direction of the inner sleeve. The sidewall of the force-applying sleeve is divided into multiple force-applying strips by multiple notches. A through groove is opened on the turntable corresponding to the force-applying strips. The pressure nut is sleeved on the inner sleeve and located above the force-applying sleeve. By screwing the pressure nut, the force-applying sleeve is driven to move axially downward, so that the force-applying strip passes through the through groove and pushes downward against the synchronization disc.

4. The sample centrifugation device according to claim 3, characterized in that, A spring is provided between the inner sleeve and the force-applying sleeve, and the spring is used to apply an upward elastic force to the force-applying sleeve.

5. The sample centrifugation device according to claim 3, characterized in that, The outer circumference of the inner sleeve is provided with external threads and axially extending plum blossom guide rails; the force-applying sleeve mates with the inner sleeve through the plum blossom guide rails, and the pressure nut mates with the inner sleeve through external threads.

6. The sample centrifugation device according to claim 1, characterized in that, A rubber bushing is provided on the wall of the insertion hole of the receiving component.

7. The sample centrifugation device according to claim 1, characterized in that, The motor is located below the turntable, and the motor drives the turntable through a rotating shaft; an axially extending plum blossom guide rail is arranged on the outer periphery of the rotating shaft, and the synchronous disc is sleeved on the rotating shaft and moves along the axial direction of the rotating shaft by cooperating with the plum blossom guide rail.

8. The sample centrifugation device according to claim 1, characterized in that, The sample centrifugation device also includes a cover; the cover has tubing arranged inside, each corresponding to a receiving component, the tubing forming a bundle at its distal end, and when the cover is fastened above the turntable, the proximal end of the tubing extends into the test tube of the receiving component.

Images