ECMO core index parameter monitoring method and portable ECMO monitor

Abstract

The application relates to an ECMO core index parameter monitoring method and a portable ECMO monitor, the application adds an intelligent monitoring function of a blood oxygen change rate on the basis of an existing ECMO system, the formed portable ECMO monitor not only has respiratory monitoring, but also has blood oxygen monitoring, can monitor the oxygenation efficiency and success rate of ECMO on blood, monitors and calculates blood oxygen entering and exiting an oxygenator, obtains a corresponding blood oxygen change rate (SpO2), and further judges whether blood oxygen meets a standard and alarms, can add oxygenation efficiency monitoring of blood oxygen of the existing ECMO, realizes efficient ECMO blood oxygen supply for patients, intuitively reflects blood oxygen change of the patients, obtains respiratory data of each ECMO device in real time, obtains blood oxygen change data, and increases the monitoring value of ECMO on patients.

Description

TECHNICAL FIELD

[0001] The present disclosure relates to the technical field of ECMO, in particular to a portable ECMO monitor, an ECMO core index parameter monitoring method and an electronic device. BACKGROUND

[0002] Extracorporeal membrane oxygenation, also known as ECMO, is a core part of a membrane lung (artificial lung) and a blood pump (artificial heart), which can provide long-term heart-lung support for patients with severe heart and lung failure, and win valuable time for the rescue of critical patients.

[0003] Extracorporeal membrane oxygenation (ECMO) technology is currently the core rescue weapon for severe heart and lung failure, also known as the last "life-saving straw" for critically ill patients, and is a technology representing the level of rescue of critically ill patients in a hospital, a region, and even a country. ECMO technology originated from extracorporeal circulation in cardiac surgery, and has been applied for less than 50 years, which has important value for rescuing critically ill patients.

[0004] After ECMO is connected to the patient's body, it provides continuous extracorporeal respiration and circulation function. When monitoring the patient with ECMO, the following index parameters are mainly monitored, including:

[0005] ECMO cardiac index:

[0006] (1) Cardiac index <2L / (m2·min) for 3 hours

[0007] (2) Metabolic acidosis BE>-5mmol for 3 hours

[0008] (3) MAP <40mmHg for neonates; <50mmHg for infants; <60mmHg for children;

[0009] (4) Oliguria <0.5ml / (kg.h)

[0010] ECMO lung index:

[0011] (1) Pulmonary oxygenation dysfunction P a O2<50mmHg or D A.a O2>620mmHg;

[0012] (2) Acute lung injury P a O2<40mmHg, pH less than 7.3 for 2 hours;

[0013] (3) Mechanical ventilation for 3 hours P a O2<55mmHg, PH less than 7.3;

[0014] (4) Airway pressure injury occurs during mechanical ventilation.

[0015] ECMO mainly includes intravascular cannula, connecting tube, blood pump (artificial heart), oxygenator (artificial lung), oxygen supply tube, respiratory monitoring system such as pressure monitor and the like. As shown in Figure 1 The working principle of ECMO is to drain the venous blood of the patient to the outside of the body, and after oxygenation and carbon dioxide removal by the membrane oxygenator (which functions like an artificial lung, referred to as a membrane lung), the blood is returned to the patient's body, thereby assuming the functions of gas exchange and / or partial blood circulation.

[0016] The existing extracorporeal membrane oxygenation ECMO has relatively conventional functions, insufficient and concentrated functions, mainly ventilation and oxygen exchange functions, and insufficient performance. ECMO is mainly used to provide continuous extracorporeal respiration and circulation for patients with severe heart and lung failure. Although blood oxygen exchange can be performed in the oxygenator, the rate of change of blood oxygen before and after exchange is not effectively monitored, and it only has the detection of the patient's respiratory ventilation volume, so it lacks blood oxygen exchange data before and after ECMO, and cannot directly reflect the change of the patient's blood oxygen. SUMMARY

[0017] To solve the above problems, the present application provides a portable ECMO monitor, an ECMO core index parameter monitoring method and an electronic device.

[0018] In one aspect of the present application, a portable ECMO monitor is provided, comprising:

[0019] A first blood oxygen collection unit is configured to collect a first blood oxygen collection signal of blood output from the oxygenator and send it to a digital conversion unit;

[0020] A second blood oxygen collection unit is configured to collect a second blood oxygen collection signal of blood input from the oxygenator and send it to the digital conversion unit;

[0021] A digital conversion unit is configured to digitally convert the first blood oxygen collection signal and the second blood oxygen collection signal, and send the corresponding blood oxygen digital signal to a controller;

[0022] A controller is configured to receive the blood oxygen digital signal and calculate the first SpO2 of blood output from the oxygenator and the second SpO2 of blood input from the oxygenator, respectively, and calculate the blood oxygen change rate during ECMO SpO2 :

[0023] ￡ SpO2 = (first SpO2) / (second SpO2);

[0024] The first blood oxygen collection unit and the second blood oxygen collection unit are respectively electrically connected to the digital conversion unit, and the digital conversion unit is electrically connected to the controller.

[0025] As an optional implementation of this application, the first SpO2 may be calculated as follows:

[0026] First SpO2 = MinSpO2(t1);

[0027] SpO2(t1) represents the digital blood oxygen signal corresponding to the first blood oxygen acquisition signal collected within the sampling period t1;

[0028] MinSpO2(t1) represents the minimum value of the blood oxygen digital signal collected within the sampling period t1. As an optional embodiment of this application, the second SpO2 may be calculated as follows:

[0029] The second SpO2 = ∑SpO2(t2) / N;

[0030] ∑SpO2(t2) represents the sum of the digital blood oxygen signals corresponding to the second blood oxygen acquisition signal collected within the sampling period t2;

[0031] N represents the number of blood oxygen digital signals corresponding to the second blood oxygen acquisition signal collected within the sampling period t2;

[0032] ∑SpO2(t2) / N represents the average value of the digital blood oxygen signal corresponding to the second blood oxygen acquisition signal collected within the sampling period t2;

[0033] Where t2 = t1.

[0034] As an optional implementation of this application, it may also include:

[0035] Battery pack, used for power supply;

[0036] The battery pack is electrically connected to the controller.

[0037] As an optional embodiment of this application, the controller may also be used for:

[0038] Assess the rate of change in blood oxygen saturation. SpO2 Is it lower than the preset value?

[0039] If the blood oxygen level is below a certain threshold, a blood oxygen monitoring alarm signal will be sent to the alarm unit; otherwise, the monitoring will be discontinued.

[0040] as well as,

[0041] The rate of change in blood oxygen ￡ SpO2 And / or the blood oxygen monitoring alarm signal, are simultaneously sent to the display unit.

[0042] As an optional implementation of this application, it may also include:

[0043] An alarm unit is configured to receive and respond to the blood oxygen monitoring alarm signal to issue an alarm.

[0044] The alarm unit is electrically connected to the controller.

[0045] As an optional embodiment of the present application, optionally further comprising:

[0046] A display unit is configured to receive and display the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal simultaneously when displaying the breathing parameters of the breathing machine.

[0047] As an optional embodiment of the present application, optionally further comprising:

[0048] A communication unit is configured to report the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal generated by the controller to an ECMO management background.

[0049] In another aspect of the present application, an ECMO core index parameter monitoring method is provided, comprising the following steps:

[0050] A first blood oxygen collection unit is configured to collect a first blood oxygen collection signal of blood output from an oxygenator and send it to a digital conversion unit;

[0051] A second blood oxygen collection unit is configured to collect a second blood oxygen collection signal of blood input from the oxygenator and send it to the digital conversion unit;

[0052] The digital conversion unit is configured to perform digital conversion on the first blood oxygen collection signal and the second blood oxygen collection signal to obtain corresponding blood oxygen digital signals and send them to the controller;

[0053] The controller is configured to receive the blood oxygen digital signals and calculate a first SpO2 of blood output from the oxygenator and a second SpO2 of blood input from the oxygenator, respectively, and calculate a current blood oxygen change rate SpO2 :

[0054] ￡ SpO2 = (first SpO2) / (second SpO2);

[0055] and

[0056] determine whether the current blood oxygen change rate SpO2 is lower than a preset value:

[0057] If it is lower, a blood oxygen monitoring alarm signal is sent to the alarm unit; otherwise, it is abandoned.

[0058] and

[0059] the current blood oxygen change rateSpO2 and / or the blood oxygen monitoring alarm signal is synchronously sent to the display unit;

[0060] The blood oxygen change rate generated by the controller this time SpO2 and / or the blood oxygen monitoring alarm signal is reported to the ECMO management background through the communication unit.

[0061] Another aspect of the present application also proposes an electronic device, comprising:

[0062] A processor;

[0063] A memory for storing processor executable instructions;

[0064] The processor is configured to implement the ECMO core index parameter monitoring method when executing the executable instructions.

[0065] Technical effects of the present application:

[0066] The present application adds an intelligent monitoring function of blood oxygen change rate on the basis of the existing ECMO system, and the formed portable ECMO monitor not only has respiratory monitoring, but also has blood oxygen monitoring, can monitor the oxygenation efficiency and success rate of ECMO on blood, and through monitoring and calculating the blood oxygen entering and exiting the oxygenator, the corresponding blood oxygen change rate is obtained SpO2 , and subsequent and further judgment of whether the blood oxygen meets the standard and alarm can increase the oxygenation efficiency monitoring of blood oxygen for the existing ECMO, realize efficient ECMO blood oxygen supply for patients, intuitively reflect the change of blood oxygen of patients, know the respiratory data of each ECMO device in real time, and know the blood oxygen change data, and the added ECMO monitoring value for patients is increased.

[0067] Other features and aspects of the present disclosure will become apparent from the following detailed description of exemplary embodiments, taken in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF DRAWINGS

[0068] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate exemplary embodiments, features, and aspects of the present disclosure and serve to explain the principles of the present disclosure.

[0069] Figure 1 A blood oxygenation flow process schematic diagram of the existing ECMO is shown;

[0070] Figure 2 A deployment position schematic diagram of the blood oxygen acquisition unit of the present application is shown;

[0071] Figure 3 An application composition schematic diagram of the portable ECMO monitor of the present application is shown;

[0072] Figure 4 An application diagram of the electronic device of the present application is shown. DETAILED DESCRIPTION

[0073] Various exemplary embodiments, features, and aspects of the present disclosure will be described in detail below with reference to the accompanying drawings. The same reference numbers in different drawings represent the same or similar elements. Although various aspects of the embodiments are illustrated in the drawings, the drawings are not necessarily drawn to scale unless specifically indicated.

[0074] The word "exemplary" is used herein to mean "serving as an example, instance, or illustration." Any implementation described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other implementations.

[0075] In addition, for the purpose of convenience and brevity, detailed descriptions of well-known devices, circuits, and methods are omitted so as not to unnecessarily obscure the teachings of the present disclosure. In some instances, well-known devices, methods, and circuits have not been described in detail in order to avoid obscuring the present disclosure.

[0076] Embodiment 1

[0077] The present scheme monitors the blood oxygen content of the blood entering the ECMO oxygenator and the blood after oxygenation by ECMO and calculates the change rate of the blood oxygen before and after, to monitor whether the oxygen concentration value after oxygenation meets the standard, whether it can normally reach the expected value and supply to the patient.

[0078] By using the present scheme, different oxygenation degrees can be set according to the disease conditions of different patients, so that the monitored blood oxygen change rate SpO2 can be used to adjust the parameters of ECMO, so that the SpO2 of the blood after the oxygenator reaches the preset value, meets the needs of the current patient and does not waste the resources of the oxygenator.

[0079] The present scheme adds the function of the existing ECMO, not only has respiratory monitoring, but also has blood oxygen change rate monitoring, which can monitor blood oxygen while monitoring respiration and match the supply, enriching the functional characteristics of the existing ECMO system.

[0080] In the present embodiment, the portable ECMO monitor can perform function upgrade on the existing ECMO equipment as shown in FIG. Figure 1 .

[0081] In one aspect of the present application, a portable ECMO monitor is provided, comprising:

[0082] The first blood oxygen acquisition unit is configured to acquire a first blood oxygen acquisition signal of the blood output from the oxygenator and send the signal to the digital conversion unit.

[0083] The second blood oxygen acquisition unit is used to acquire the second blood oxygen acquisition signal of the blood input from the oxygenator and send it to the digital conversion unit;

[0084] The digital conversion unit is used to perform digital conversion on the first blood oxygen acquisition signal and the second blood oxygen acquisition signal, and send the corresponding blood oxygen digital signal to the controller.

[0085] The controller receives the digital blood oxygen signal and calculates the first SpO2 of the blood output from the oxygenator and the second SpO2 of the blood input from the oxygenator, and calculates the rate of change of blood oxygen during the ECMO procedure. SpO2 :

[0086] £ SpO2 = (first SpO2) / (second SpO2);

[0087] The first blood oxygen acquisition unit and the second blood oxygen acquisition unit are electrically connected to the digital conversion unit, and the digital conversion unit is electrically connected to the controller.

[0088] like Figure 2 As shown, both the first and second blood oxygen acquisition units are blood oxygen detectors. Their blood oxygen acquisition probes can be installed at the output and input ends of the oxygenator, respectively. The first blood oxygen acquisition unit is used to acquire the first blood oxygen acquisition signal (the blood oxygen saturation acquisition signal after the blood has been processed by the oxygenator) of the blood output from the oxygenator. The second blood oxygen acquisition unit is used to acquire the second blood oxygen acquisition signal (the blood oxygen saturation acquisition signal before the blood has been processed by the oxygenator) of the blood input from the oxygenator.

[0089] The digital conversion unit can be a time-to-digital converter (TDC) that can acquire the signal timing and quantity of the signals acquired by the two acquisition units within a certain acquisition period. Within the sampling period t, the blood oxygen values ​​from the output and input are monitored, and after the corresponding signals are acquired, they are processed by the digital conversion unit and sent to the controller for calculation to obtain the corresponding SpO2.

[0090] like Figure 3 As shown, the controller can perform calculations on the first and second blood oxygen acquisition signals after digital conversion to obtain the corresponding SpO2, namely the first SpO2, which is the blood oxygen saturation value in the original blood before being input into the oxygenator, and the second SpO2, which is the blood oxygen saturation value in the blood output after the oxygenator's activation processing.

[0091] The rate of change in blood oxygen saturation is calculated using a ratio. SpO2 Under normal ECMO conditions, £ Sp O2 is a number greater than 1.

[0092] The controller calculates the value of SpO2 Afterwards, it can be sent and displayed on the display unit of the ventilator, and displayed synchronously with the respiratory data of the ECMO. In this way, the patient has the functions of respiratory monitoring and blood oxygen monitoring.

[0093] As an optional embodiment of the present application, the first SpO2 is calculated in the following manner:

[0094] First SpO2 = MinSpO2 (t1);

[0095] SpO2 (t1) represents the blood oxygen digital signal corresponding to the first blood oxygen acquisition signal collected in the sampling period t1;

[0096] MinSpO2 (t1) represents the minimum value of the blood oxygen digital signal collected in the sampling period t1.

[0097] For example, in a sampling period t1 = 1s, the first blood oxygen acquisition unit collects three output blood oxygen signal values, in order to optimize the expression of the oxygenation conversion rate of blood oxygen, a minimum value is obtained from the three blood oxygen signal values at the output end, and the minimum value MinSpO2 (t1) is taken as the output value of the present sampling period, which is used to represent the maximum oxygenation efficiency in the present period. The blood oxygen value in the present sampling period is represented by the minimum value, and if the minimum value meets the preset comparison, the other sampling data in the present period also meets.

[0098] The blood oxygen acquisition unit reports signal data once every sampling period, and the controller also calculates and sends the latest blood oxygen calculation result to the display unit once every sampling period, for real-time updating of the blood oxygen change rate.

[0099] As an optional embodiment of the present application, the second SpO2 is calculated in the following manner:

[0100] Second SpO2 = ∑SpO2 (t2) / N;

[0101] ∑SpO2 (t2) represents the sum of the blood oxygen digital signals corresponding to the second blood oxygen acquisition signal collected in the sampling period t2;

[0102] N represents the number of blood oxygen digital signals corresponding to the second blood oxygen acquisition signal collected in the sampling period t2;

[0103] ∑SpO2 (t2) / N represents the average value of the blood oxygen digital signals corresponding to the second blood oxygen acquisition signal collected in the sampling period t2;

[0104] Wherein, t2 = t1.

[0105] The second SpO2 is calculated by using the average value in the sampling period. The calculation method of the above-mentioned SpO2(t1) can also be used. For example, in a sampling period t2=1s, the second blood oxygen acquisition unit acquires three output blood oxygen signal values. The average value of the three blood oxygen signal values at the input end is calculated to obtain the second SpO2.

[0106] The controller calculates the blood oxygen change rate￡ SpO2 every other sampling period, and sends and displays the blood oxygen change rate￡

[0107] As an optional embodiment of the present application, optionally further comprising:

[0108] a battery pack for power supply;

[0109] The battery pack is electrically connected with the controller. Preferably, a lithium battery is used for power supply.

[0110] As an optional embodiment of the present application, optionally, the controller is further used for:

[0111] judging whether the current blood oxygen change rate￡ SpO2 is lower than a preset value:

[0112] if yes, sending a blood oxygen monitoring alarm signal to an alarm unit; otherwise, giving up;

[0113] and

[0114] synchronously sending the current blood oxygen change rate￡ SpO2 and / or the blood oxygen monitoring alarm signal to a display unit.

[0115] The preset value can be used to represent the oxygenation efficiency of an oxygenator, such as 1.15. If the calculated current blood oxygen change rate￡ SpO2 is lower than 1.15, it may mean that the oxygenation time and other parameters of the oxygenator do not meet the standards, and the ECMO process needs to be continued. If it is lower than 1, it means that the ECMO function has a problem, and the administrator needs to be prompted to maintain, repair, etc.

[0116] As an optional embodiment of the present application, optionally further comprising:

[0117] an alarm unit for receiving and responding to the blood oxygen monitoring alarm signal to perform alarm reminding;

[0118] The alarm unit is electrically connected with the controller.

[0119] The alarm unit can be integrally arranged on the respirator of the ECMO, and responds after receiving the alarm signal sent by the controller. A buzzer alarm and the like can be used.

[0120] As an optional embodiment of the present application, optionally further comprising:

[0121] The display unit is used to receive and display the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal.

[0122] The display unit is used to receive and display the current blood oxygen change rate SpO 2 and / or the blood oxygen monitoring alarm signal.

[0123] The display unit is used to receive and display the current blood oxygen change rate SpO2 and the blood oxygen monitoring alarm signal.

[0124] As an optional embodiment of the present application, optionally further comprising:

[0125] The communication unit is used to report the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal generated by the controller to the ECMO management background.

[0126] The ECMO management background can be an ECMO background management software deployed on a hospital background server, which can receive the data reported by the communication unit and record it in real time in the background database.

[0127] The communication unit can be a 5G module, which can report the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal generated by the controller to the ECMO management background. The communication between the 5G module and the background server is not described in detail.

[0128] The 5G module also reports the current blood oxygen change rate SpO2 to the ECMO management background every other sampling period. The ECMO management background can generate a corresponding blood oxygen change rate chart according to the received current blood oxygen change rate SpO2 . The patient can log in to the ECMO background management software after logging in to the background server, and the generated blood oxygen change rate chart can be saved in real time under the patient's identity, so that the patient can view his own blood oxygen change data in real time after logging in to the background.

[0129] On the basis of the above, the respiratory data can also be sent to the ECMO management background synchronously, and a corresponding respiratory chart is generated. After the patient logs in to the background, the patient can see the respiratory data change chart and the blood oxygen rate change data at the same time.

[0130] The ECMO management background can also initiate access and remind notification to the nursing center according to the reported blood oxygen monitoring alarm signal, and the nursing center can issue the blood oxygen monitoring alarm signal of each patient to the handheld PDA device of the corresponding nursing staff, so that the corresponding nursing staff can go to the patient to perform ECMO nursing.

[0131] In addition to the above blood oxygen monitoring, the ECMO clinical important monitoring data can also be concentrated on a small and portable, simple to install, and accurate measuring instrument, so as to solve the problem that the old machine cannot monitor the data, and the new machine cannot monitor the branch flow in the VAV mode. The new portable ECMO monitoring instrument has the following function structure:

[0132] 1. Monitoring probe of commonly used and important data: flow, speed, hemoglobin, blood temperature, arterial and venous pressure (integrated monitoring data: flow, hemoglobin, blood temperature); specific probes or sensors can be used for data acquisition, such as flow, a corresponding flow sensor can be used, and the flow sensor is connected to the controller in the appendix Figure 3 The hemoglobin can be calculated by near-infrared spectroscopy image detection method. Red or near-infrared light is relatively easy to penetrate biological bodies. A light receiving element (CMOS camera) is arranged opposite to the light source (LED) penetrating the biological body, so that the vascular transmission image inside the biological body can be obtained. The concentration of the vascular image obtained through the transmission image is determined according to the light attenuation degree of blood, that is, the amount of hemoglobin in blood. Therefore, by irradiating with LEDs having wavelengths of 660 nm (wavelength with a large light absorption coefficient of reduced hemoglobin), 805 nm (wavelength with equal light absorption coefficients of reduced and oxidized hemoglobin), and 880 nm, transmission images of each wavelength band can be obtained, and the amount of hemoglobin can be calculated by the concentration of the vascular image. Further, the width of the blood vessel is obtained through the image, and the estimated amount of hemoglobin per unit volume of blood is calculated.

[0133] 2. Host screen displays commonly used data: measurement data can be reviewed at any time, select the corresponding playback record, press the confirmation key, and display the trend chart playback screen; the display unit can be used for display, the measurement data is reported to the ECMO management background, and the data is issued during subsequent playback and displayed on the display unit.

[0134] 3. Intelligent prompting system: the measurement data can set the prompting range, the machine will automatically prompt; set threshold for each measurement value, and use the program of the controller to monitor whether each value is over standard, and send corresponding alarm prompt signal to the alarm unit;

[0135] 4. Pipe clamp: the monitoring probe or sensing probe of each instrument is fixed on the pipe to be monitored by ECMO. The clamp structure of the pipe clamp is not limited in the scheme.

[0136] The installation position and quantity of each monitoring probe or sensing probe are not limited in the embodiment.

[0137] Obviously, those skilled in the art should understand that all or part of the processes in the above embodiments can be completed by a computer program instructing related hardware, and the program can be stored in a computer readable storage medium. The program can include the processes of the above-mentioned control embodiments when executed. Those skilled in the art can understand that all or part of the processes in the above embodiments can be completed by a computer program instructing related hardware, and the program can be stored in a computer readable storage medium. The program can include the processes of the above-mentioned control embodiments when executed. The storage medium can be a magnetic disk, an optical disk, a read-only memory (ROM), a random access memory (RAM), a flash memory, a hard disk drive (HDD) or a solid state drive (SSD), etc. The storage medium can also include a combination of the above types of memories.

[0138] Embodiment 2

[0139] Based on the implementation principle of embodiment 1, another aspect of the present application proposes an ECMO core index parameter monitoring method, comprising the following steps:

[0140] The first blood oxygen acquisition unit acquires the first blood oxygen acquisition signal of the blood output from the oxygenator and sends it to the digital conversion unit;

[0141] The second blood oxygen acquisition unit acquires the second blood oxygen acquisition signal of the blood input from the oxygenator and sends it to the digital conversion unit;

[0142] The digital conversion unit digitally converts the first blood oxygen acquisition signal and the second blood oxygen acquisition signal to obtain the corresponding blood oxygen digital signal and sends it to the controller;

[0143] The controller receives the blood oxygen digital signal and calculates a first SpO2 of blood output from the oxygenator and a second SpO2 of blood input into the oxygenator, respectively, and calculates a current blood oxygen change rate SpO2 :

[0144] ￡ SpO2 = (the first SpO2) / (the second SpO2) ;

[0145] and,

[0146] determines whether the current blood oxygen change rate SpO2 is lower than a preset value:

[0147] if lower, sends a blood oxygen monitoring alarm signal to an alarm unit; otherwise, gives up;

[0148] and,

[0149] sends the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal to a display unit synchronously;

[0150] reports the current blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal generated by the controller to an ECMO management background through a communication unit.

[0151] The execution of the above steps can be understood with reference to the functions of Embodiment 1, and will not be repeated here.

[0152] The portable ECMO monitor of the present application has a shell and the like, which are not limited in the present embodiment, and the device can be configured as a system according to the application of the present embodiment. The portable ECMO monitor can provide portable respiratory and blood oxygen nursing monitoring for patients, and enrich the monitoring function of ECMO.

[0153] The modules or steps of the present application described above can be realized by a general computing device, which can be concentrated on a single computing device or distributed on a network composed of multiple computing devices. Alternatively, they can be realized by program codes executable by a computing device, so that they can be stored in a storage device and executed by a computing device, or they can be respectively manufactured into individual integrated circuit modules, or multiple modules or steps among them can be manufactured into a single integrated circuit module to realize. Thus, the present application is not limited to any specific combination of hardware and software.

[0154] Embodiment 3

[0155] As shown in Figure 4 , further, another aspect of the present application also proposes an electronic device, comprising:

[0156] a processor;

[0157] a memory for storing processor-executable instructions;

[0158] wherein the processor is configured to implement the ECMO core indicator parameter monitoring method when executing the executable instructions.

[0159] The electronic device according to any one of the preceding embodiments comprises a processor and a memory for storing processor-executable instructions. The processor is configured to implement the ECMO core indicator parameter monitoring method when executing the executable instructions.

[0160] It should be noted that the number of processors can be one or more. Meanwhile, the electronic device according to the embodiments of the present disclosure can further comprise an input device and an output device. The processor, the memory, the input device and the output device can be connected through a bus or other means, which is not limited here.

[0161] The memory, as a computer readable storage medium, can be used to store software programs, computer executable programs and various modules, such as programs or modules corresponding to the ECMO core indicator parameter monitoring method according to the embodiments of the present disclosure. The processor executes the software programs or modules stored in the memory, thereby performing various functional applications and data processing of the electronic device.

[0162] The input device can be used to receive input numbers or signals. The signals can be key signals related to user settings and function control of the device / terminal / server. The output device can include a display device such as a display screen.

[0163] The above has described the embodiments of the present disclosure, and the above description is exemplary, not exhaustive, and is not limited to the disclosed embodiments. Many modifications and changes are obvious to those skilled in the art without departing from the scope and spirit of the described embodiments. The selection of terms used herein is intended to best explain the principles, practical application or technical improvement of technology in the market of the embodiments, or to enable other ordinary skilled persons in the art to understand the embodiments disclosed herein.

Claims

1. A portable ECMO monitor, combining blood oxygen monitoring, ECMO blood oxygenation efficiency and success rate monitoring functions, capable of simultaneously obtaining respiratory data and blood oxygenation change data for each ECMO device in real time, characterized in that, include: The first blood oxygen acquisition unit is used to acquire the first blood oxygen acquisition signal of the blood output from the oxygenator and send it to the digital conversion unit; The second blood oxygen acquisition unit is used to acquire the second blood oxygen acquisition signal of the blood input from the oxygenator and send it to the digital conversion unit; The first and second blood oxygen acquisition units are both blood oxygen detectors. Their blood oxygen acquisition probes are installed at the output and input ends of the oxygenator, respectively. The first blood oxygen acquisition unit is used to acquire the first blood oxygen acquisition signal of the blood output from the oxygenator, and the second blood oxygen acquisition unit is used to acquire the second blood oxygen acquisition signal of the blood input from the oxygenator. The digital conversion unit is used for digital conversion of the first blood oxygen collection signal and the second blood oxygen collection signal, and sends the corresponding blood oxygen digital signal to the controller; the digital conversion unit adopts a time-to-digital converter, which can collect the signal time sequence and quantity of the collected signals of the two collection units within a certain collection period, monitor the output and input blood oxygen values within a sampling period t, obtain the corresponding signals, process the signals through the digital conversion unit, and send the signals to the controller; the controller calculates SpO2 Then, the data is sent and displayed on the display unit of the respirator, and is displayed synchronously with the respiratory data of the ECMO. a controller for receiving the blood oxygen digital signals and calculating a first SpO2 of blood output from the oxygenator and a second SpO2 of blood input into the oxygenator, respectively, and calculating a current blood oxygen change rate £ SpO2 : £ SpO2 = (first SpO2) / (second SpO2), The first SpO2 is calculated as follows: First SpO2 = MinSpO2(t1); SpO2(t1) represents the digital blood oxygen signal corresponding to the first blood oxygen acquisition signal collected within the sampling period t1; MinSpO2(t1) represents the minimum value of the blood oxygen digital signal collected within the sampling period t1, which is used to represent the maximum oxygenation efficiency within this period; The second SpO2 is calculated as follows: Second SpO2 / N; a sum value representing a blood oxygen digital signal corresponding to the second blood oxygen collection signal collected in a sampling period t2, N represents the number of digital blood oxygen signals corresponding to the second blood oxygen acquisition signal collected within the sampling period t2. N represents the mean value of the blood oxygen digital signal corresponding to the second blood oxygen collection signal collected in the sampling period t2, wherein t2 = t1; The first blood oxygen acquisition unit and the second blood oxygen acquisition unit are respectively electrically connected to the digital conversion unit, and the digital conversion unit is electrically connected to the controller; The controller is also used to: determine the rate of change of blood oxygen in this instance. SpO2 Is it lower than the preset value? The preset value is used to characterize the oxygenation efficiency of the oxygenator, which is 1.

15. If the blood oxygen change rate is £ SpO2 1.15, a blood oxygen monitoring alarm signal is sent to the alarm unit, indicating that the oxygenation time parameter of the oxygenator has not met the standard, and the ECMO process needs to continue; if the blood oxygen change rate is £ SpO2 1, it means that the ECMO function has a problem, and the administrator needs to be prompted to maintain and repair the ECMO; otherwise, it is abandoned; And, the blood oxygen change rate £ SpO2 And / or the blood oxygen monitoring alarm signal is synchronously sent to a display unit.

2. The portable ECMO monitor according to claim 1, characterized in that, Also includes: Battery pack, used for power supply; The battery pack is electrically connected to the controller.

3. The portable ECMO monitor according to claim 1, characterized in that, Also includes: The alarm unit is used to receive and respond to the blood oxygen monitoring alarm signal and provide an alarm reminder; The alarm unit is electrically connected to the controller.

4. The portable ECMO monitor according to claim 1, characterized in that, Also includes: a display unit for synchronously receiving and displaying the blood oxygen change rate SpO2 and / or the blood oxygen monitoring alarm signal while displaying the breathing parameters of the breathing machine.

5. The portable ECMO monitor according to claim 1, characterized in that, Also includes: A communication unit is configured to report the blood oxygen change rate £ SpO2 and / or the blood oxygen monitoring alarm signal to an ECMO management background.

6. A method for monitoring core ECMO parameters, implemented using a portable ECMO monitor as described in any one of claims 1-5, characterized in that, Includes the following steps: The first blood oxygen acquisition signal of the blood output from the oxygenator is acquired by the first blood oxygen acquisition unit and sent to the digital conversion unit; The second blood oxygen acquisition unit acquires the second blood oxygen acquisition signal of the blood input from the oxygenator and sends it to the digital conversion unit; The first and second blood oxygen acquisition units are both blood oxygen detectors. Their blood oxygen acquisition probes are installed at the output and input ends of the oxygenator, respectively. The first blood oxygen acquisition unit is used to acquire the first blood oxygen acquisition signal of the blood output from the oxygenator, and the second blood oxygen acquisition unit is used to acquire the second blood oxygen acquisition signal of the blood input from the oxygenator. The first blood oxygen collection signal and the second blood oxygen collection signal are digitally converted by a digital conversion unit to obtain corresponding blood oxygen digital signals and then sent to a controller; the digital conversion unit adopts a time-to-digital converter, which can collect the signal time sequence and quantity of the collected signals of the two collection units within a certain collection period, monitor the output and input blood oxygen values within a sampling period t, obtain the corresponding signals, process the signals through the digital conversion unit, and send the signals to the controller; the controller calculates SpO2 Then, the data is sent and displayed on the display unit of the respirator, and is displayed synchronously with the respiratory data of the ECMO. The controller receives the blood oxygen digital signals and calculates a first SpO2 of blood output from the oxygenator and a second SpO2 of blood input to the oxygenator, respectively, and calculates a blood oxygen change rate £ of this time of ECMO SpO2 : SpO2 = (first Sp02) / (second Sp02);​ The first SpO2 is calculated as follows: First SpO2 = MinSpO2(t1); SpO2(t1) represents the digital blood oxygen signal corresponding to the first blood oxygen acquisition signal collected within the sampling period t1; MinSpO2(t1) represents the minimum value of the blood oxygen digital signal collected within the sampling period t1, which is used to represent the maximum oxygenation efficiency within this period; The second SpO2 is calculated as follows: Second SpO2= / N; This represents the sum of the digital blood oxygen signals corresponding to the second blood oxygen acquisition signal collected within the sampling period t2. N represents the number of digital blood oxygen signals corresponding to the second blood oxygen acquisition signal collected within the sampling period t2. / N represents the average value of the blood oxygen digital signal corresponding to the second blood oxygen acquisition signal collected within the sampling period t2, where t2=t1; The controller judges whether the blood oxygen change rate of this time is lower than a preset value SpO2 The preset value is used to represent the oxygenation efficiency of the oxygenator as 1.

15. If the blood oxygen change rate is £ SpO2 1.15, a blood oxygen monitoring alarm signal is sent to the alarm unit, indicating that the oxygenation time parameter of the oxygenator has not met the standard, and the ECMO process needs to continue; if the blood oxygen change rate is £ SpO2 1, indicating that the ECMO function has a problem, the administrator needs to be prompted to maintain and repair the ECMO; otherwise, it is abandoned; And, the blood oxygen change rate £ SpO2 And / or the blood oxygen monitoring alarm signal is sent to the display unit synchronously; the blood oxygen change rate £ SpO2 And / or the blood oxygen monitoring alarm signal is reported to the ECMO management background through the communication unit.

7. An electronic device, characterized in that, include: processor; Memory used to store processor-executable instructions; The processor is configured to implement the ECMO core indicator parameter monitoring method of claim 6 when executing the executable instructions.

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