A traditional Chinese medicine composition for treating closed soft tissue injuries and its preparation method

Abstract

The present invention discloses a traditional Chinese medicine composition for treating closed soft tissue injuries and a preparation method thereof, belonging to the technical field of external therapeutic drugs for soft tissue injuries. The present invention solves the problems that although the external drugs for treating soft tissue injuries in the prior art have good curative effects, their components are complex and the costs are high. Calculated by weight parts, it includes the following drugs: 120-180 parts of Phellodendri Chinensis Cortex, 30-70 parts of Rhei Radix et Rhizoma, 30-70 parts of Heraclei Pubescentis Radix, 30-70 parts of Aucklandiae Radix, 30-70 parts of Chuanxiong Rhizoma, 30-70 parts of Typhae Pollen, 30-70 parts of Angelicae Dahuricae Radix, 30-70 parts of Carthami Flos, 15-40 parts of Sappan Lignum, 15-40 parts of Myrrha, and 15-40 parts of Kochiae Fructus. The present invention is mainly used for the early stage of closed soft tissue injuries and those with redness, swelling, heat, and pain in the injured part. When placed on the affected part, the medicinal power can directly reach the diseased site, with rapid onset, less pain, few adverse reactions, safety and reliability, and being easily acceptable to patients.

Description

Technical Field

[0001] The present invention belongs to the technical field of external therapeutic drugs for soft tissue injuries, and particularly relates to a traditional Chinese medicine composition for treating closed soft tissue injuries and a preparation method thereof. Background Art

[0002] Closed soft tissue injury refers to a situation where the local skin or mucous membrane is intact without a crack communicating with the outside world, and the bleeding during the injury accumulates within the tissue. It is a type of soft tissue injury. The bleeding during the injury accumulates within the tissue. Common ones include contusions, muscle strains, bone hyperplasia, arthritis, etc. If it is the early stage of an acute injury, within 48 hours, it is manifested as local redness, swelling, heat, pain, and dysfunction. At this time, cold compress, pressure bandage, and elevation of the affected limb can be given. After 48 hours, hot compress is given to improve the local blood circulation, which is beneficial to reducing edema and promoting healing.

[0003] Closed soft tissue injuries are very common clinically, and there are also an endless stream of drugs for treating closed soft tissue injuries. For example, the patent with the patent number CN1242804C discloses an external drug for treating traumatic injuries and its preparation method. It can be used to treat traumatic injuries such as soft tissue injuries. Although its curative effect is good, its composition is complex, with more than forty kinds of medicinal materials, which will undoubtedly greatly increase the treatment cost of patients and increase the treatment burden of patients. Summary of the Invention

[0004] Aiming at the problem that although the external drugs for treating soft tissue injuries in the prior art have good curative effects, their compositions are complex and the costs are high, the present invention provides a traditional Chinese medicine composition for treating closed soft tissue injuries and a preparation method thereof.

[0005] The technical scheme adopted by the present invention is as follows:

[0006] A traditional Chinese medicine composition for treating closed soft tissue injuries and a preparation method thereof, calculated by weight, includes the following drugs: 120 - 180 parts of Phellodendri Chinensis Cortex, 30 - 70 parts of Rhei Radix et Rhizoma, 30 - 70 parts of Angelicae Pubescentis Radix, 30 - 70 parts of Aucklandiae Radix, 30 - 70 parts of Chuanxiong Rhizoma, 30 - 70 parts of Pollen Typhae, 30 - 70 parts of Angelicae Dahuricae Radix, 30 - 70 parts of Carthami Flos, 15 - 40 parts of Sappan Lignum, 15 - 40 parts of Myrrha, and 15 - 40 parts of Kochiae Fructus.

[0007] Phellodendri Chinensis Cortex is used for damp-heat diarrhea, jaundice with reddish urine, leukorrheal itching, heat strangury with pain, beriberi flaccidity, bone steaming fever, night sweats, spermatorrhea, sores and ulcers, eczema and damp sores;

[0008] Rhei Radix et Rhizoma is used for constipation due to accumulation of excessive heat, hematemesis and epistaxis due to blood heat, red eyes and swollen throat, carbuncles and sores, appendicitis with abdominal pain, stasis of blood in menstruation, postpartum stasis obstruction, traumatic injury, damp-heat dysentery, jaundice with reddish urine, stranguria syndrome, edema, and externally for burns and scalds;

[0009] Angelica pubescens is used for wind-cold-damp arthralgia, pain in the waist and knees, headache due to latent wind pathogen in Shaoyin meridian, headache due to wind-cold pathogen with dampness;

[0010] Aucklandia root is used for promoting qi flow to relieve pain, strengthening the spleen and promoting digestion;

[0011] Chuanxiong rhizome is used for promoting blood circulation and qi flow, dispelling wind and relieving pain;

[0012] Pollen typhae has the effects of astringing to arrest bleeding, activating blood circulation to remove stasis, and inducing diuresis to relieve stranguria;

[0013] Angelica dahurica has the effects of inducing sweating to dispel cold, dispelling wind and relieving pain, dredging nasal orifices, drying dampness and arresting leukorrhea, and detumescing and discharging pus;

[0014] Safflower has the effects of activating blood circulation to dredge the meridian, dispersing stasis and relieving pain, and can be taken orally or topically;

[0015] Myrrh has the effects of dispersing stasis and relieving pain, detumescing and promoting granulation;

[0016] Fructuskochiae has the effects of clearing heat and promoting diuresis, dispelling wind and relieving itching.

[0017] After adopting this technical solution, the traditional Chinese medicine composition is composed of Phellodendron amurense, Rheum palmatum, Angelica pubescens, Aucklandia root, Chuanxiong rhizome, Pollen typhae, Angelica dahurica, etc. The formula is simple, and its functions are to reduce fever, detumesce and relieve pain. It is mainly used for the early stage of closed soft tissue injury and those with redness, swelling, heat and pain in the injured part. When placed on the affected part, the medicinal power can directly reach the disease site, with rapid onset, less pain, few adverse reactions, safety and reliability, and being easily acceptable to patients.

[0018] Preferably, by weight, it includes the following drugs: 150 parts of Phellodendron amurense, 50 parts of Rheum palmatum, 50 parts of Angelica pubescens, 50 parts of Aucklandia root, 50 parts of Chuanxiong rhizome, 50 parts of Pollen typhae, 50 parts of Angelica dahurica, 50 parts of safflower, 25 parts of Sappanwood, 25 parts of myrrh, and 25 parts of Fructuskochiae.

[0019] Preferably, it includes the following drugs: 150 g of Phellodendron amurense, 50 g of Rheum palmatum, 50 g of Angelica pubescens, 50 g of Aucklandia root, 50 g of Chuanxiong rhizome, 50 g of Pollen typhae, 50 g of Angelica dahurica, 50 g of safflower, 25 g of Sappanwood, 25 g of myrrh, and 25 g of Fructuskochiae.

[0020] A preparation method of a traditional Chinese medicine composition for treating closed soft tissue injury is to first grind the drugs into powder according to the ratio, mix the powder evenly, and then mix the powder with a blending agent to form a paste for later use.

[0021] To sum up, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0022] 1. In the present invention, Phellodendron amurense is used as the monarch drug, supplemented by Rheum palmatum, and together they achieve the effect of cooling blood and stopping bleeding. Heracleum hemsleyanum and Angelica dahurica are used to reduce swelling and relieve pain, Akebia quinata and Ligusticum wallichii are used to dredge collaterals and promote qi flow, and Carthamus tinctorius is used to promote blood circulation to remove blood stasis and relieve pain by promoting qi flow. The combination of these herbs can promote blood circulation to remove blood stasis, dredge collaterals to reduce swelling and relieve pain, relax muscles and tendons, accelerate blood circulation, promote the absorption of blood stasis, and accelerate the recovery of ankle joint injuries.

[0023] 2. The preparation method of the traditional Chinese medicine composition provided by the present invention is simple. It only needs to grind the medicinal materials into powder and then mix them into a paste for application on the affected area, with strong operability.

[0024] 3. The present invention is composed of Phellodendron amurense, Rheum palmatum, Heracleum hemsleyanum, Aucklandia lappa, Ligusticum wallichii, Typha angustata, Angelica dahurica, etc. The formula is simple, and its functions are to reduce fever, swelling, and pain. It is mainly used for the early stage of closed soft tissue injury and those with redness, swelling, heat, and pain in the affected area. When placed on the affected part, the medicinal power can directly reach the disease site, with rapid onset, less pain, few adverse reactions, being safe and reliable, and being easily accepted by patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 is the preparation flow chart of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0026] To make the objectives, technical solutions, and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below. Apparently, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments.

[0027] Example 1

[0028] A traditional Chinese medicine composition for treating closed soft tissue injury, including 150 g of Phellodendron amurense, 50 g of Rheum palmatum, 50 g of Heracleum hemsleyanum, 50 g of Aucklandia lappa, 50 g of Ligusticum wallichii, 50 g of Typha angustata, 50 g of Angelica dahurica, 50 g of Carthamus tinctorius, 25 g of Sappanwood, 25 g of Myrrh, and 25 g of Kochia scoparia.

[0029] As Figure 1 shown, the preparation method of the above traditional Chinese medicine composition is as follows: Grind 150 g of Phellodendron amurense, 50 g of Rheum palmatum, 50 g of Heracleum hemsleyanum, 50 g of Aucklandia lappa, 50 g of Ligusticum wallichii, 50 g of Typha angustata, 50 g of Angelica dahurica, 50 g of Carthamus tinctorius, 25 g of Sappanwood, 25 g of Myrrh, and 25 g of Kochia scoparia into powder and mix them evenly. When in use, take an appropriate amount of the powder and mix it with an appropriate amount of yellow rice wine and petrolatum to form a paste for use. The ratio of yellow rice wine and petrolatum can be adjusted as needed as long as the powder can be made into an ointment.

[0030] Example 2

[0031] A traditional Chinese medicine composition for treating closed soft tissue injuries, comprising 160 g of Phellodendri Chinensis Cortex, 60 g of Rhei Radix et Rhizoma, 60 g of Heraclei Pubescentis Radix, 60 g of Aucklandiae Radix, 60 g of Chuanxiong Rhizoma, 60 g of Typhae Pollen, 60 g of Angelicae Dahuricae Radix, 60 g of Carthami Flos, 30 g of Sappan Lignum, 30 g of Myrrha, and 30 g of Kochiae Fructus.

[0032] As Figure 1 shown, the preparation method of the above traditional Chinese medicine composition is as follows: Grind 160 g of Phellodendri Chinensis Cortex, 60 g of Rhei Radix et Rhizoma, 60 g of Heraclei Pubescentis Radix, 60 g of Aucklandiae Radix, 60 g of Chuanxiong Rhizoma, 60 g of Typhae Pollen, 60 g of Angelicae Dahuricae Radix, 60 g of Carthami Flos, 30 g of Sappan Lignum, 30 g of Myrrha, and 30 g of Kochiae Fructus into powder and mix evenly. When in use, take an appropriate amount of the powder and mix it with an appropriate amount of yellow rice wine and vaseline to form a paste for use. The ratio of yellow rice wine to vaseline can be adjusted as needed, as long as the powder can be made into an ointment.

[0033] Example 3

[0034] A traditional Chinese medicine composition for treating closed soft tissue injuries, comprising 140 g of Phellodendri Chinensis Cortex, 40 g of Rhei Radix et Rhizoma, 40 g of Heraclei Pubescentis Radix, 40 g of Aucklandiae Radix, 60 g of Chuanxiong Rhizoma, 40 g of Typhae Pollen, 40 g of Angelicae Dahuricae Radix, 40 g of Carthami Flos, 20 g of Sappan Lignum, 20 g of Myrrha, and 20 g of Kochiae Fructus.

[0035] As Figure 1 shown, the preparation method of the above traditional Chinese medicine composition is as follows: Grind 140 g of Phellodendri Chinensis Cortex, 40 g of Rhei Radix et Rhizoma, 40 g of Heraclei Pubescentis Radix, 40 g of Aucklandiae Radix, 60 g of Chuanxiong Rhizoma, 40 g of Typhae Pollen, 40 g of Angelicae Dahuricae Radix, 40 g of Carthami Flos, 20 g of Sappan Lignum, 20 g of Myrrha, and 20 g of Kochiae Fructus into powder and mix evenly. Take an appropriate amount of the powder and mix it with an appropriate amount of yellow rice wine and vaseline to form a paste for use. The ratio of yellow rice wine to vaseline can be adjusted as needed, as long as the powder can be made into an ointment.

[0036] Select 189 patients with soft tissue injuries, including 106 males and 83 females, aged between 8 and 65 years. The 189 patients have obvious symptoms of soft tissue injuries, such as severe pain, swelling, and limb movement dysfunction. Treat them with the traditional Chinese medicine composition of Example 1 of the present invention. Apply the prepared paste to the affected area and change it once a day. Observe the effects after applying for 3 days, 5 days, and 7 days continuously. The effect results are shown in Table 1. The calculation formulas for the effective rate and cure rate are as follows:

[0037]

[0038] The effect evaluation criteria are as follows:

[0039] Cured: Redness, swelling, heat, and pain disappear, and the attached or adjacent joints can move freely.

[0040] Markedly effective: Redness, swelling, and heat disappear, with slight soreness, and the movement of the attached or adjacent joints is basically not restricted.

[0041] Effective: The redness, swelling, heat, and pain are alleviated, and the movement of the attached or adjacent joints is slightly restricted.

[0042] Ineffective: The redness, swelling, heat, and pain show no improvement, and the joint movement is restricted.

[0043] Table 1

[0044] Recovery Marked effect Effective Ineffective Effective rate Cure rate 3 days 119 62 8 0 100％ 62.96％ 5 days 165 22 2 0 100％ 87.30％ 7 days 188 1 0 0 100％ 99.47％

[0045] Inventor The following are typical cases in the diagnosis and treatment process of the inventor:

[0046] Case 1

[0047] Zhao XX, male, 19 years old, was hit by a companion while playing basketball and fell to the ground. There was swelling, bruising, and severe pain in the ankle, with limited walking ability and obvious tenderness. He went to the hospital 3 hours after the fall and started using the traditional Chinese medicine composition of Example 1 on the same day, changing the medicine once a day. After using it for 5 hours, the pain was significantly relieved. The swelling was significantly improved on the second day, and the redness, swelling, heat, pain, and bruising completely disappeared on the third day, and he could walk freely.

[0048] Case 2

[0049] Li X, female, 25 years old, exerted too much force and bent backward excessively during yoga exercise, resulting in damage to the soft tissue between the vertebrae. She went to the hospital the next day. There was obvious swelling in the soft tissue between the vertebrae, and it was difficult to stand upright. She started using the traditional Chinese medicine composition of Example 1 on the same day, changing the medicine once a day. After using it for 3 hours, the pain was significantly relieved. The swelling basically subsided on the second day, with no obvious pain, and she could stand upright.

[0050] Case 3

[0051] Wen XX, male, 9 years old, accidentally fell while riding a bicycle and had pain and swelling in the knee joint, unable to straighten and walk. After using Yunnan Baiyao at home for 2 days with no obvious effect, he was sent to the hospital. He started using the traditional Chinese medicine composition of Example 1 on the same day, changing the medicine once a day. The knee joint could move slowly on the second day of use, and the swelling and pain symptoms basically disappeared after five days, and he could walk freely.

[0052] Case 4

[0053] Li XX, female, 56 years old, slipped and fell while mopping the floor at home, landing on her buttocks, with severe pain, bruising on the buttocks, local muscle stiffness, and severe pain during movement. She was sent to the hospital by her family on the same day and started using the traditional Chinese medicine composition of Example 1 on the same day, changing the medicine once a day. Most of the swelling on the buttocks subsided on the third day of use, but there was still pain during movement. After 6 days, the swelling and bruising basically dissipated, and there was no obvious pain during movement.

[0054] Case 4

[0055] Li XX, female, 56 years old. When mopping the floor at home, she slipped and fell, landing on her buttocks. She felt severe pain, with bruising on the buttocks, local muscle stiffness, and severe pain when moving. She was sent to the hospital by her family on the same day and started using the traditional Chinese medicine composition of Example 1, changing the medicine once a day. On the third day of use, most of the swelling and redness on the buttocks subsided, but there was still pain when moving. After 6 days, the swelling, redness, and bruising basically dissipated, and there was no obvious pain when moving.

[0056] The above cases show that the effective rate of the present invention can reach 100%, the cure rate within 3 days reaches 62.96%, and the cure rate within 7 days is as high as 99.47%. The formula is simple and the effect is quick. It can promote blood circulation to remove stasis, dredge collaterals, reduce swelling and relieve pain, relax muscles and activate collaterals, accelerate blood circulation, promote the absorption of stasis, and accelerate the recovery of soft tissue injuries.

[0057] The above embodiments only represent the specific implementation manners of the present application. The description is relatively specific and detailed, but it should not be construed as a limitation on the protection scope of the present application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the technical solution of the present application, several deformations and improvements can still be made, and these all belong to the protection scope of the present application.

Claims

1. A traditional Chinese medicine composition for treating closed soft tissue injuries, characterized in that: composed of the following medicines by weight: 150 parts of Phellodendron amurense, 50 parts of Rheum palmatum, 50 parts of Heracleum hemsleyanum, 50 parts of Aucklandia lappa, 50 parts of Ligusticum chuanxiong, 50 parts of Typha angustifolia, 50 parts of Angelica dahurica, 50 parts of Carthamus tinctorius, 25 parts of Caesalpinia sappan, 25 parts of Myrrh, and 25 parts of Kochia scoparia.

2. The traditional Chinese medicine composition for treating closed soft tissue injuries according to claim 1, characterized in that: composed of the following medicines: 150 g of Phellodendron amurense, 50 g of Rheum palmatum, 50 g of Heracleum hemsleyanum, 50 g of Aucklandia lappa, 50 g of Ligusticum chuanxiong, 50 g of Typha angustifolia, 50 g of Angelica dahurica, 50 g of Carthamus tinctorius, 25 g of Caesalpinia sappan, 25 g of Myrrh, and 25 g of Kochia scoparia.

3. A preparation method of the traditional Chinese medicine composition for treating closed soft tissue injuries according to any one of claims 1-2, characterized in that: first, the medicines according to any one of claims 1-2 are ground into powders according to the ratio, and the powders are mixed evenly, and then the powders are mixed with a conditioner to form a paste for later use.

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