Extracorporeal membrane oxygenation system and control method

Abstract

The application provides an extracorporeal membrane oxygenation system and a control method, which can be used in the field of medical instruments. In the system, the blood pump in the extracorporeal membrane oxygenation system is connected with the oxygenator, a gas temperature and humidity adjusting unit is arranged in the connecting path between the oxygenator and the gas source device, and the gas temperature and humidity adjusting unit is used for adjusting the temperature and humidity of the gas flowing into the oxygenator; the control device in the extracorporeal membrane oxygenation system is connected with the blood pump and the gas temperature and humidity adjusting unit respectively; the control device determines the working parameter data corresponding to the gas temperature and humidity adjusting unit according to the operation parameter data of the extracorporeal membrane oxygenation device, and then controls the gas temperature and humidity adjusting unit to work according to the working parameter data, so that the gas reaches the target temperature and humidity. According to the scheme, the temperature and humidity of the gas flowing into the oxygenator are adjusted by controlling the working of the gas temperature and humidity adjusting unit to make the gas reach the target temperature and humidity, and the water loss of the blood in the extracorporeal circulation loop can be reduced.

Description

Technical Field

[0001] This application relates to the field of medical devices, and more particularly to an extracorporeal membrane oxygenation (ECMO) system and its control method. Background Technology

[0002] Extracorporeal membrane oxygenation (ECMO) devices are used to provide continuous extracorporeal respiration and circulation for patients with severe cardiopulmonary failure. They can temporarily replace the patient's cardiopulmonary function and reduce the burden on the patient's heart and lungs.

[0003] In existing technologies, ECMO devices work by using a blood pump to draw blood from a target object, such as a patient or blood bag, into an oxygenator. After oxygenation in the oxygenator, the blood is then returned to the patient or blood bag to maintain its oxygen content. During use, gas is supplied to the ECMO device from a gas source to achieve blood oxygenation.

[0004] However, the operating parameters of extracorporeal membrane oxygenation (ECMO) devices vary depending on the scenario in which they are used. In some special cases, such as when the gas flow rate is high, the gas in the oxygenator will carry away water from the blood during gas exchange, resulting in water loss from the blood. Summary of the Invention

[0005] This application provides an extracorporeal membrane oxygenation (ECMO) system and control method to address the urgent need for an ECMO system and control method that can reduce the amount of water loss in the extracorporeal circulation loop during the use of an ECMO device.

[0006] In a first aspect, embodiments of this application provide an extracorporeal membrane oxygenation (ECMO) system, the ECMO system comprising: an oxygenator, a blood pump, a gas temperature and humidity control unit, a gas source device, and a control device;

[0007] The blood pump is connected to the oxygenator, and the blood pump, the oxygenator, and the target object are connected to form a circulation loop;

[0008] The oxygenator is connected to the gas source device, and the gas temperature and humidity regulating unit is disposed in the connection path between the oxygenator and the gas source device. The gas temperature and humidity regulating unit is used to regulate the temperature and humidity of the gas flowing into the oxygenator.

[0009] The control device is connected to the blood pump and the gas temperature and humidity regulating unit, respectively.

[0010] The control device is used to control the operation of the gas temperature and humidity regulating unit so that the gas reaches the target temperature and humidity, which corresponds to the operating parameter data of the extracorporeal membrane oxygenation system.

[0011] The beneficial effects of this embodiment are as follows: In the extracorporeal membrane oxygenation (ECMO) system, the blood pump is connected to the oxygenator. A gas temperature and humidity regulating unit is installed in the connection path between the oxygenator and the gas source equipment. This unit regulates the temperature and humidity of the gas flowing into the oxygenator. A control device is connected to both the blood pump and the gas temperature and humidity regulating unit. The control device controls the operation of the gas temperature and humidity regulating unit to ensure the gas reaches the target temperature and humidity, which corresponds to the operating parameters of the ECMO system. This solution regulates the temperature and humidity of the gas flowing into the oxygenator by controlling the gas temperature and humidity regulating unit to achieve the target temperature and humidity, thereby reducing water loss in the extracorporeal circulation loop.

[0012] In one specific embodiment, the gas temperature and humidity regulating unit includes a gas washing device and a first temperature control device;

[0013] The gas outlet of the gas source device is connected to the gas inlet of the gas scrubbing device, the gas outlet of the gas scrubbing device is connected to the gas inlet of the oxygenator, and the gas scrubbing device stores a preset liquid, which is used to humidify the gas entering the gas scrubbing device.

[0014] The gas washing device is disposed in the accommodating cavity of the first temperature control device, and the second temperature control device is used to regulate the temperature of the preset liquid.

[0015] The beneficial effects of this implementation method are: by using a gas washing device and a first temperature control device, the temperature and humidity of the gas flowing into the oxygenator can be regulated, which can effectively and timely regulate the gas temperature and humidity.

[0016] In one specific embodiment, the gas washing device further includes a liquid delivery interface, and the gas temperature and humidity regulating unit further includes a first liquid delivery component, which is connected to the liquid delivery interface and is used to replenish or extract the preset liquid.

[0017] The beneficial effects of this implementation are: through the first liquid infusion component, liquid can be replenished or extracted from the gas washing device, ensuring that the gas washing device can regulate the gas humidity.

[0018] In one specific embodiment, the target object includes a blood storage device, and the extracorporeal membrane oxygenation system further includes a second temperature control device, the second temperature control device including a temperature-controlled accommodating cavity for accommodating the blood storage device, and the first temperature control device for controlling the temperature of the blood in the blood storage device.

[0019] The beneficial effect of this implementation is that the temperature of the blood in the blood storage device can be controlled by the second temperature control device, thus achieving the goal of keeping the blood warm.

[0020] In one specific embodiment, the blood storage device includes a liquid bag, and the extracorporeal membrane oxygenation system further includes: a container corresponding to the liquid bag, the liquid bag being placed in liquid contained in the container, the container being provided with a liquid level scale, the liquid level scale being used to indicate the amount of change in the volume of liquid in the liquid bag.

[0021] The beneficial effects of this implementation are: by setting a liquid level scale on the container, the volume of liquid in the bag can be detected, thereby effectively measuring the amount of water loss caused by gas exchange in the blood under different operating parameters, which helps to determine the correspondence between ECMO operating parameters and the gas temperature and humidity control unit.

[0022] In one specific embodiment, the extracorporeal membrane oxygenation system further includes a liquid level detection unit, which is used to detect the water level of the liquid in the container.

[0023] The beneficial effects of this implementation method are: the liquid level detection unit can detect the liquid level in the bag with high accuracy.

[0024] In one specific embodiment, the extracorporeal membrane oxygenation system further includes a second infusion assembly for delivering fluid to the target object.

[0025] The beneficial effect of this implementation is that by delivering liquid to the target object through the second infusion component, water can be replenished when the target object is dehydrated.

[0026] In one specific embodiment, the control device is used to control the operation of the second infusion assembly to deliver liquid to the target object.

[0027] The beneficial effects of this implementation are: by controlling the operation of the second infusion component through the control equipment, the machine control of the second infusion component can be realized, thereby replenishing water in a timely manner.

[0028] In a second aspect, embodiments of this application provide a control method for an extracorporeal membrane oxygenation (ECMO) system, applied to the ECMO system described in any one of the first aspects, the method comprising:

[0029] Obtain operational parameter data for the extracorporeal membrane oxygenation (ECMO) device;

[0030] Based on the operating parameter data, determine the corresponding operating parameter data for the gas temperature and humidity regulating unit;

[0031] Based on the operating parameter data, the gas temperature and humidity regulating unit is controlled to operate so that the gas reaches the target temperature and humidity, which corresponds to the operating parameter data.

[0032] The beneficial effects of this embodiment are as follows: After obtaining the operating parameter data of the extracorporeal membrane oxygenation (ECMO) device, the corresponding working parameter data of the gas temperature and humidity control unit is determined. Based on this working parameter data, the gas temperature and humidity control unit is controlled to ensure that the gas reaches the target temperature and humidity, which corresponds to the operating parameter data. This solution determines the working parameter data based on the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop.

[0033] In one specific embodiment, the operating parameter data includes at least one of air flow data and blood flow data.

[0034] The beneficial effects of this implementation method are: by determining the working parameter data through at least one of the gas flow rate data and blood flow rate data, the accuracy of gas temperature and humidity regulation can be made more precise, and the amount of water loss in the extracorporeal circulation loop can be minimized under different blood flow rate and gas flow rate conditions.

[0035] In one specific embodiment, the gas flow data includes at least one of gas flow detection data and gas flow correlation data, wherein the gas flow correlation data is used to characterize the flow rate of the gas.

[0036] The beneficial effects of this implementation are: by using at least one of the gas flow detection data and gas flow correlation data to measure gas flow, the device can determine the corresponding operating parameter data based on any gas flow data. This allows the above-mentioned gas temperature and humidity regulation strategy to cover more blood flow conditions. The application of the solution is not limited by the type of gas flow data collected, and the amount of water loss in the extracorporeal circulation loop can be minimized under different blood flow conditions.

[0037] In one specific embodiment, the gas source device includes a gas flow regulating unit, and the gas flow associated data includes the operating parameter data corresponding to the gas flow regulating unit.

[0038] The beneficial effects of this implementation are: by using the working parameter data of the gas flow regulation unit in the gas source equipment as gas flow correlation data, the gas flow rate can be indirectly measured, and the above-mentioned gas temperature and humidity regulation can be achieved without the need for a gas flow sensor.

[0039] In one specific embodiment, the blood flow data includes at least one of blood flow detection data and blood flow association data, wherein the blood flow association data is used to characterize the blood flow in the circulatory loop.

[0040] The beneficial effects of this implementation are: by determining the working parameter data through at least one of the blood flow detection data and blood flow correlation data, the above-mentioned gas temperature and humidity regulation strategy can cover more blood flow conditions, making the accuracy of gas temperature and humidity regulation more precise, and minimizing the amount of water loss in the extracorporeal circulation loop under different blood flow conditions.

[0041] In one specific embodiment, the blood flow-related data includes at least one of the following: blood pump speed, blood pump current value, and blood pump differential pressure data.

[0042] The beneficial effects of this implementation are: by using at least one of the blood pump speed, blood pump current value, and blood pump differential pressure data as blood flow-related data, blood flow can be indirectly measured, and the above-mentioned gas temperature and humidity regulation can be achieved without the need for a blood flow sensor.

[0043] In one specific embodiment, the method further includes:

[0044] Acquire the temperature data of the gas flowing into the oxygenator;

[0045] If the temperature data of the gas is outside the preset temperature range, output gas temperature alarm information.

[0046] The beneficial effects of this implementation are: when the gas temperature data is outside the preset temperature range, a gas temperature alarm message is output, which effectively ensures the safety of the extracorporeal membrane oxygenation system and also ensures the safety of the target object.

[0047] In one specific embodiment, the method further includes:

[0048] Obtain humidity data of the gas flowing into the oxygenator;

[0049] If the humidity data is outside the target humidity range, a preset alarm message is output. The preset alarm message is used to indicate the risk of water loss or abnormal gas humidity of the target object.

[0050] The beneficial effects of this implementation method are: when the humidity data is outside the target humidity range, a preset alarm message is output, which effectively ensures the safety of the extracorporeal membrane oxygenation system and also ensures the safety of the target object.

[0051] In one specific embodiment, the method further includes:

[0052] Determine the preset humidity range corresponding to the operating parameter data;

[0053] The preset humidity range is determined as the target humidity range.

[0054] The beneficial effect of this implementation method is that by determining the target humidity range based on the operating parameter data, the target humidity range becomes more accurate.

[0055] In one specific embodiment, the method further includes:

[0056] Obtain the patient treatment strategy corresponding to the control device;

[0057] The step of determining the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data includes:

[0058] Based on the operating parameter data and the patient treatment strategy, determine the operating parameter data corresponding to the gas temperature and humidity control unit;

[0059] The target temperature and humidity are the target values ​​corresponding to the operating parameter data under the patient treatment strategy.

[0060] The beneficial effects of this implementation method are: by combining the patient's treatment strategy, the corresponding working parameter data under the strategy can be determined, making the determined working parameter data more accurate, realizing the adjustment of gas temperature and humidity according to the strategy, and optimizing the blood water loss in the extracorporeal circulation loop.

[0061] Thirdly, embodiments of this application provide a control device for an extracorporeal membrane oxygenation (ECMO) system, comprising:

[0062] The acquisition module is used to acquire the operating parameter data of the extracorporeal membrane oxygenation system;

[0063] The processing module is used to determine the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data.

[0064] The control module is used to control the gas temperature and humidity regulating unit to operate based on the operating parameter data, so that the gas reaches the target temperature and humidity, which corresponds to the operating parameter data.

[0065] The beneficial effects of this embodiment are as follows: After obtaining the operating parameter data of the extracorporeal membrane oxygenation (ECMO) device, the corresponding working parameter data of the gas temperature and humidity regulation unit is determined. Based on this working parameter data, the gas temperature and humidity regulation unit is controlled to achieve the target temperature and humidity, which corresponds to the operating parameter data. This solution determines the working parameter data based on the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop.

[0066] Fourthly, embodiments of this application provide an electronic device, including:

[0067] Processor, memory, communication interface;

[0068] The memory is used to store the executable instructions of the processor;

[0069] The processor is configured to execute the control method of the extracorporeal membrane oxygenation system according to any of the second aspects by executing the executable instructions.

[0070] The beneficial effects of this embodiment are as follows: After obtaining the operating parameter data of the extracorporeal membrane oxygenation (ECMO) device, the corresponding working parameter data of the gas temperature and humidity regulation unit is determined. Based on this working parameter data, the gas temperature and humidity regulation unit is controlled to achieve the target temperature and humidity, which corresponds to the operating parameter data. This solution determines the working parameter data based on the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop.

[0071] Fifthly, embodiments of this application provide a readable storage medium having a computer program stored thereon, wherein the computer program, when executed by a processor, implements the control method of the extracorporeal membrane oxygenation system as described in any of the second aspects.

[0072] The beneficial effects of this embodiment are as follows: After obtaining the operating parameter data of the extracorporeal membrane oxygenation (ECMO) device, the corresponding working parameter data of the gas temperature and humidity regulation unit is determined. Based on this working parameter data, the gas temperature and humidity regulation unit is controlled to achieve the target temperature and humidity, which corresponds to the operating parameter data. This solution determines the working parameter data based on the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop.

[0073] In a sixth aspect, embodiments of this application provide a computer program product, including a computer program, which, when executed by a processor, is used to implement the control method of the extracorporeal membrane oxygenation system as described in any of the second aspects.

[0074] The beneficial effects of this embodiment are as follows: After obtaining the operating parameter data of the extracorporeal membrane oxygenation (ECMO) device, the corresponding working parameter data of the gas temperature and humidity regulation unit is determined. Based on this working parameter data, the gas temperature and humidity regulation unit is controlled to achieve the target temperature and humidity, which corresponds to the operating parameter data. This solution determines the working parameter data based on the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop. Attached Figure Description

[0075] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0076] Figure 1 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 1 ;

[0077] Figure 2 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 2 ;

[0078] Figure 3 A schematic diagram of the gas washing bottle provided in this application;

[0079] Figure 4 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 3 ;

[0080] Figure 5 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 4 ;

[0081] Figure 6 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 5 ;

[0082] Figure 7 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 6 ;

[0083] Figure 8 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 7 ;

[0084] Figure 9 A schematic flowchart of an embodiment of the control method for the extracorporeal membrane oxygenation system provided in this application;

[0085] Figure 10 A schematic flowchart of Embodiment 2 of the control method for the extracorporeal membrane oxygenation system provided in this application;

[0086] Figure 11 A schematic flowchart of Embodiment 3 of the control method for the extracorporeal membrane oxygenation system provided in this application;

[0087] Figure 12 A schematic flowchart of Embodiment 4 of the control method for the extracorporeal membrane oxygenation system provided in this application;

[0088] Figure 13 A schematic diagram of the structure of an embodiment of the control device for the extracorporeal membrane oxygenation system provided in this application;

[0089] Figure 14 This is a schematic diagram of the structure of an electronic device provided in this application. Detailed Implementation

[0090] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments made by those skilled in the art under the guidance of these embodiments are within the scope of protection of this application.

[0091] The terms “first,” “second,” “third,” “fourth,” etc. (if present) in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a particular order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms “comprising” and “having,” and any variations thereof, are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0092] With the development of technology, more and more medical devices have emerged. Extracorporeal membrane oxygenation (ECMO) devices, which include a blood pump and an oxygenator, can provide cardiopulmonary function and provide valuable time for patient resuscitation.

[0093] ECMO devices are used to provide continuous extracorporeal respiration and circulation for patients with severe cardiopulmonary failure, temporarily replacing the patient's cardiopulmonary function and reducing the burden on the patient's heart and lungs.

[0094] In existing technologies, ECMO devices are used in both testing and application scenarios. In both scenarios, the working principle of ECMO devices is to draw deoxygenated blood from the patient's venous system or blood bag, oxygenate it, and then reinfuse it into the patient's body or blood bag to maintain the oxygen content in the blood.

[0095] In the testing scenario, the inventors built a testing system according to the ASTM 1841-19 standard to test the ECMO device. According to the requirements of the ISO 7199 standard, the test needed to be conducted under conditions of maximum blood flow and maximum gas flow achievable by the ECMO device. The tests revealed that after 6 hours of ECMO operation, the total blood volume decreased from 700 mL to 400 mL, the hematocrit (Hct) increased from 38% to 45%, and the humidity at the gas outlet at the bottom of the oxygenator at the ECMO device's terminal decreased from 90% RH to 16% RH, indicating that a higher gas flow rate leads to a reduction in water content in the blood.

[0096] When using extracorporeal membrane oxygenation (ECMO) equipment in different scenarios, the operating parameters of the ECMO equipment will be different. In some special cases, such as when the gas flow rate is high, the gas in the oxygenator will take away the water in the blood when exchanging gases with the blood, resulting in water loss in the blood.

[0097] To address the problems existing in the prior art, the inventors, during their research on extracorporeal membrane oxygenation (ECMO) systems, discovered that in the application of ECMO devices, to reduce water loss in the extracorporeal circulation loop, an ECMO system including a gas temperature and humidity control unit can be constructed, positioned between the oxygenator and the gas source device. The control equipment in the control system can determine the operating parameters based on the operating parameter data of the ECMO system, and then control the gas temperature and humidity control unit to operate according to these parameters, ensuring that the gas flowing into the oxygenator reaches the target temperature and humidity. Based on the above inventive concept, the ECMO system and control method described in this application were designed.

[0098] The technical solution of this application will now be described in detail through specific embodiments. It should be noted that the following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be described again in some embodiments.

[0099] Figure 1 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 1 ,like Figure 1 As shown, the test system of the extracorporeal membrane oxygenation (ECMO) device includes: an oxygenator 11, a blood pump 12, a gas temperature and humidity control unit 13, a gas source device 14, and a control device 15.

[0100] The blood pump 12 is connected to the oxygenator 11, and the blood pump 12 and the oxygenator 11 are also connected to the target object to form a circulation loop.

[0101] The oxygenator 11 is connected to the gas source device 14. The gas temperature and humidity regulating unit 13 is located in the connection path between the oxygenator 11 and the gas source device 14. The gas temperature and humidity regulating unit 13 is used to regulate the temperature and humidity of the gas flowing into the oxygenator 11.

[0102] The control device 15 is connected to the blood pump 12 and the gas temperature and humidity control unit 13 respectively.

[0103] When using the extracorporeal membrane oxygenation (ECMO) system, the control device 16 first determines the operating parameter data corresponding to the gas temperature and humidity regulating unit 13 based on the acquired operating parameter data of the ECMO system. Then, it controls the blood pump 12 to operate, and controls the gas temperature and humidity regulating unit 13 to operate according to the operating parameter data, so that the gas flowing into the oxygenator 11 reaches the target temperature and humidity, which corresponds to the operating parameter data of the ECMO system.

[0104] Blood pump 12 operates, and the blood from the target object reaches oxygenator 11 through blood pump 12. Gas source device 14 outputs gas, which passes through gas temperature and humidity regulating unit 13 before reaching oxygenator 11. When the gas passes through gas temperature and humidity regulating unit 13, the gas temperature and humidity regulating unit 13 regulates the gas temperature and humidity, thereby regulating the water content of the blood during the oxygenation process in oxygenator 11; the blood then flows from oxygenator 11 to the target object, completing blood circulation.

[0105] The extracorporeal membrane oxygenation (ECMO) system provided in this embodiment connects a blood pump to an oxygenator. A gas temperature and humidity regulating unit is installed in the connection path between the oxygenator and the gas source device. This unit regulates the temperature and humidity of the gas flowing into the oxygenator. The control device in the ECMO system is connected to both the blood pump and the gas temperature and humidity regulating unit. Based on the operating parameters of the ECMO system, the control device determines the corresponding operating parameters of the gas temperature and humidity regulating unit and then controls the unit to operate according to these parameters to achieve the target temperature and humidity for the gas. Compared to existing technologies that cannot regulate the water content of a target object, this solution regulates the temperature and humidity of the gas flowing into the oxygenator by controlling the gas temperature and humidity regulating unit to achieve the target temperature and humidity. This reduces or prevents the gas from carrying away water from the blood during gas exchange in the oxygenator, thereby reducing water loss in the extracorporeal circulation loop.

[0106] Based on the above embodiments, the gas temperature and humidity regulating unit will be described below.

[0107] exist Figure 1 On this basis, Figure 2 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 2 ,like Figure 2As shown, the gas temperature and humidity regulating unit 13 includes a first temperature control device 16 and a gas scrubbing device 17.

[0108] The gas outlet of the gas source device 14 is connected to the gas inlet of the gas scrubbing device 17, and the gas outlet of the gas scrubbing device 17 is connected to the gas inlet of the oxygenator 11. The gas scrubbing device 17 stores a preset liquid, which is used to humidify the gas entering the gas scrubbing device 17.

[0109] The gas washing device 17 is disposed in the accommodating cavity of the first temperature control device 16, which is used to regulate the temperature of the preset liquid.

[0110] The gas washing device 17 can be a gas washing bottle, for example. Figure 3 A schematic diagram of the gas washing bottle provided in this application; as shown Figure 3 As shown, the gas washing bottle contains a preset liquid. For the two openings on the top of the gas washing bottle, the right opening is the gas inlet and the left opening is the gas outlet.

[0111] The control device 15 can determine the operating parameter data of the first temperature control device 16 based on the operating parameter data, and then the first temperature control device 16 operates according to the operating parameter data. The first temperature control device 16 can adjust the temperature of the preset liquid in the gas washing device 17. As the gas flows through the gas washing device 17, the gas temperature and humidity are regulated, thereby reducing the amount of water lost from the blood in the extracorporeal circulation circuit.

[0112] The extracorporeal membrane oxygenation system provided in this embodiment includes a gas washing device and a first temperature control device in its gas temperature and humidity regulation unit. Through the gas washing device and the first temperature control device, the gas temperature and humidity can be regulated, thereby reducing the amount of water lost from the blood in the extracorporeal circulation loop.

[0113] Based on the above embodiments, the following description will explain the case where the gas temperature and humidity regulating unit also includes a first infusion component.

[0114] exist Figure 2 On this basis, Figure 4 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 3 ,like Figure 4 As shown, the gas washing device 17 also includes a liquid delivery interface, and the gas temperature and humidity regulating unit 13 also includes a first liquid delivery component 18. The first liquid delivery component 18 is connected to the liquid delivery interface and is used to replenish or extract a preset liquid.

[0115] The control device 15 can be connected to the first infusion assembly 18 to control the operation of the first infusion assembly to replenish or extract a preset liquid. When the gas temperature and humidity regulating unit 13 is working to humidify the gas, the control device 15 can control the first infusion assembly 18 to replenish the preset liquid; when the gas temperature and humidity regulating unit 13 is working but not humidifying the gas, the control device 15 can control the first infusion assembly 18 to extract the preset liquid.

[0116] It should be noted that the first infusion component can be a syringe, an infusion pump and its pumped fluid bag tubing, etc. The embodiments of this application do not limit the first infusion component, and it can be determined according to the actual situation.

[0117] The extracorporeal membrane oxygenation system provided in this embodiment can replenish or extract the preset liquid in the gas washing device through the first infusion component, thereby achieving gas humidity regulation.

[0118] The following describes the testing process using an extracorporeal membrane oxygenation (ECMO) system.

[0119] exist Figure 1 On this basis, Figure 5 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 4 ,like Figure 5 As shown, during the test, the target objects included a blood storage device, and the extracorporeal membrane oxygenation system also included a second temperature control device 19.

[0120] The second temperature control device 19 includes a temperature-controlled accommodating cavity for accommodating the blood storage device, and is used to control the temperature of the blood in the blood storage device. The blood storage device is connected to the blood pump 12 and the oxygenator 11.

[0121] During the testing process, the gas source device 14 operates at a preset gas flow rate; the second temperature control device 19 controls the temperature of the blood in the blood storage device to ensure that the blood temperature is the same as the normal human body temperature; the control device 15 controls the blood pump 12 to operate at a preset blood flow rate. The control device 15 controls the gas temperature and humidity regulating unit 13 to operate according to the working parameter data. When the blood pump 12 is running, blood can flow out from the blood storage device, pass through the blood pump 12, and reach the oxygenator 11. The gas source device 15 outputs gas, which passes through the gas temperature and humidity regulating unit 13 and reaches the oxygenator 11. When the gas passes through the gas temperature and humidity regulating unit 13, the gas temperature and humidity regulating unit 13 will regulate the temperature and humidity of the gas, thereby regulating the water content of the blood during the oxygenation process of the blood in the oxygenator 11; the blood then flows from the oxygenator 11 to the blood storage device, completing the blood circulation.

[0122] It should be noted that the control device 15 can be connected to the second temperature control device 19 to control the operation of the second temperature control device 19.

[0123] It should be noted that during the test, the preset air flow rate is the preset air flow rate corresponding to the maximum air flow rate that the oxygenator 11 can achieve. This application embodiment does not limit the preset air flow rate, and it can be set according to the actual situation.

[0124] It should be noted that the control device 15 can control the blood pump 12 to operate at a preset blood flow rate in two ways: controlling the current of the blood pump to a preset current; or controlling the speed of the blood pump to a preset speed. During the test, the preset blood flow rate is the maximum blood flow rate that the oxygenator 11 can achieve. This embodiment does not limit the preset blood flow rate, preset current, or preset speed, and these can be set according to the actual situation.

[0125] The control device 15 controls the blood pump 12 to operate for a preset duration. Then, the tester can obtain a blood sample from the blood storage device, place it in the testing device for analysis, obtain the blood's test parameter values, and calculate and output the hemolysis index based on these values. The tester can then determine the hemolysis index and evaluate the degree of blood cell damage and blood compatibility based on it. A higher hemolysis index indicates a worse degree of blood cell loss and poorer blood compatibility.

[0126] It should be noted that the preset running time can be 1 hour, 2 hours, 6 hours, etc. This application embodiment does not limit the preset running time, and it can be set according to the actual situation.

[0127] Specifically, the detection parameters include hematocrit and current free hemoglobin concentration. Combined with blood volume, preset blood flow rate, pre-test free hemoglobin concentration, preset test duration, and pre-test total hemoglobin concentration, the hemolysis index can be obtained. The hemolysis index includes the Normalized Index of Hemolysis (NIH) and the Modified Index of Hemolysis (MIH).

[0128] The NIH calculation formula is as follows: Wherein, ΔPfH represents the increase in free hemoglobin concentration, which can be obtained by calculating the difference between the current free hemoglobin concentration and the free hemoglobin concentration before the test, in mg / dL; V represents blood volume in mL; Hct represents hematocrit; Q represents preset blood flow rate in L / min; and ΔT represents preset running time in min.

[0129] The formula for calculating MIH is: Wherein, ΔPfH represents the increase in free hemoglobin concentration, which can be obtained by calculating the difference between the current free hemoglobin concentration and the free hemoglobin concentration before the test, in mg / dL; V represents blood volume in mL; Hct represents hematocrit; Q represents preset blood flow rate in L / min; ΔT represents preset running time in min; and Hgb represents total hemoglobin concentration before the test in g / dL.

[0130] It should be noted that the free hemoglobin concentration and total hemoglobin concentration before the test are determined by the test personnel using testing equipment to detect the blood before the test.

[0131] The extracorporeal membrane oxygenation system provided in this embodiment regulates the temperature of the blood in the blood storage device through a second temperature control device, ensuring that the blood temperature is consistent with the human blood temperature during the test. Combined with the gas temperature and humidity regulation unit, it regulates the temperature and humidity of the gas, ensuring that the water content of the blood in the blood storage device remains unchanged during the test, which can effectively improve the accuracy of the test.

[0132] Since the control equipment determines the operating parameter data based on the correspondence between the running parameter data and the operating parameter data, the following explanation describes the situation of determining this correspondence through experiments using an extracorporeal membrane oxygenation system.

[0133] exist Figure 1 On this basis, Figure 6 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 5 ,like Figure 6 As shown, the blood storage device includes a liquid bag, which is connected to the blood pump 12 and the oxygenator 11. The extracorporeal membrane oxygenation system also includes a container 20 corresponding to the liquid bag. The liquid bag is placed in the liquid contained in the container 20. The container 20 is provided with a liquid level scale, which is used to indicate the change in the volume of liquid in the liquid bag.

[0134] Before the experiment, the blood-filled bag was placed in container 20, and liquid was added to container 20. The liquid level was observed to ensure that the liquid level reached the target level.

[0135] With a fixed set of operating parameters, the gas temperature and humidity control unit 13 is run multiple times, each time with different operating parameters, thereby controlling the blood pump. After each run, the current liquid level is observed. By comparing the current level with the target level, it can be determined whether the water content in the blood increases or decreases during the process, and the corresponding amount of change. This experiment is repeated multiple times until the current level matches the target level, meaning the change is zero. The target operating parameter is then determined, and a correspondence is established between this operating parameter and the target operating parameter. Further adjustments to the operating parameters and repeated experiments yield multiple correspondences between operating parameter data and the target operating parameter data.

[0136] In practical applications, after multiple experiments, the optimal correspondence between ECMO operating parameters such as bleeding flow rate, gas flow rate, blood pump speed, blood pump current, and pressure difference before and after the blood pump and gas temperature and humidity can be determined (minimizing blood water loss). Through this correspondence, a temperature and humidity configuration that matches the actual operating conditions can be selected, thereby controlling the gas to reach the target temperature and humidity and minimizing the amount of blood water loss in the oxygenator in real time.

[0137] It should be noted that, in order to improve the accuracy of the determined change in liquid volume, a liquid level detection unit can be installed in the extracorporeal membrane oxygenation system. For example, in... Figure 6 On this basis, Figure 7 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 6 ,like Figure 7 As shown, the extracorporeal membrane oxygenation system also includes a liquid level detection unit 21, which is used to detect the water level of the liquid in the container 20.

[0138] Before the experiment, a blood-filled bag is placed in container 20, and liquid is added to container 20. The liquid level in container 20 is determined by the liquid level detection unit 21, ensuring that the liquid level reaches the target level. After the experiment is completed, the current liquid level is determined by the liquid level detection unit 21, and thus the change in liquid volume can be determined.

[0139] It should be noted that the liquid level detection unit 21 can be placed on the outer wall of the container 20, the inner wall of the container 20, or inside the container 20. This application embodiment does not limit the placement of the liquid level detection unit 21, and it can be determined according to the actual situation.

[0140] For example, the total blood volume of the liquid bag is controlled to be 700mL. The liquid bag is placed in container 20 and liquid is added to container 20. By observing the liquid level scale, the liquid level is made to reach the target liquid level scale.

[0141] For a fixed set of operating parameters, three different operating parameters are set. When the gas temperature and humidity control unit 13 operates with the first operating parameter, the gas flowing into the oxygenator 11 is pure gas without heating or humidification, forming a pure gas circulation. After conducting the experiment for 3 hours according to this operating parameter, the change in liquid volume is a decrease of 150 mL, and the blood water loss rate is 50 mL / h.

[0142] When the gas temperature and humidity control unit 13 operates with the second working parameter, it only humidifies the gas flowing into the oxygenator 11, and the gas temperature is room temperature, forming a humidification cycle. After conducting the experiment for 3 hours according to this working parameter, the change in liquid volume is a decrease of 90 mL, and the blood water loss rate is 30 mL / h.

[0143] When the gas temperature and humidity control unit 13 operates at the third working parameter, it can humidify and heat the gas flowing into the oxygenator 11. The gas temperature can be the same as the blood temperature, forming a warm and humid gas circulation. After conducting the experiment for 3 hours according to this working parameter, the change in liquid volume is 0 mL, and the blood water loss rate is 0 mL / h.

[0144] Therefore, by heating and humidifying the gas, the amount of water lost from the blood during the gas exchange process in the oxygenator can be effectively reduced or even avoided.

[0145] The extracorporeal membrane oxygenation (ECMO) system provided in this embodiment can detect the change in liquid volume within the container during experiments through the container included in the ECMO system, making the experimental results more accurate and the correspondence between the obtained operating parameter data and the working parameter data more accurate.

[0146] The following describes the situation where liquid can be directly delivered to the target object.

[0147] For example, in Figure 1 On this basis, Figure 8 Schematic diagram of the extracorporeal membrane oxygenation system provided in this application Figure 7 ,like Figure 8 As shown, the extracorporeal membrane oxygenation system also includes a second infusion assembly 22, which is used to deliver fluid to the target object.

[0148] When the target is the human body, in order to keep the blood water content constant, in addition to using the gas temperature and humidity regulating unit for regulation, when the blood water content decreases, the second infusion assembly 22 can also be used to deliver liquid to the human body to keep the blood water content constant.

[0149] During testing using an extracorporeal membrane oxygenation (ECMO) system, the target object includes a blood storage device. The second infusion unit 22 can be used to directly deliver fluid to the blood storage device to ensure that the blood water content remains unchanged and improve the accuracy of the test results.

[0150] During the experiment using the extracorporeal membrane oxygenation system, after each run, liquid can be delivered to the liquid bag through the second infusion component 22 so that the water level in the container reaches the target liquid level mark or the target water level again. The volume of liquid delivered by the second infusion component 22 can be used as the change in liquid volume.

[0151] It should be noted that the control device 15 can be connected to the second infusion assembly to control the operation of the second infusion assembly to deliver liquid to the target object, thereby improving the accuracy of the delivered liquid volume.

[0152] It should be noted that the second infusion component can be a syringe, an infusion pump and its pumped fluid bag tubing, etc. The embodiments of this application do not limit the second infusion component, and it can be determined according to the actual situation.

[0153] The extracorporeal membrane oxygenation (ECMO) system provided in this embodiment delivers fluid to the target object through a second infusion component. When the target object is a human body, it can reduce the amount of water lost from the blood. During testing using the ECMO system, the blood water content can be kept constant, making the calculated hemolysis index more accurate and improving the accuracy of the test results. During experiments using the ECMO system, the accuracy of the determined change in fluid volume can be improved, thereby making the correspondence between the obtained operating parameter data and the working parameter data more accurate.

[0154] Figure 9 This is a flowchart illustrating an embodiment of the control method for the extracorporeal membrane oxygenation (ECMO) system provided in this application. The executing entity in this embodiment is the control device in the aforementioned test system. This embodiment describes how the control device determines operating parameter data based on the operating parameter data of the ECMO system, and then controls the gas temperature and humidity regulating unit to operate according to the operating parameter data. The method in this embodiment can be implemented through software, hardware, or a combination of both. Figure 9 As shown, the control method of this extracorporeal membrane oxygenation system specifically includes the following steps:

[0155] S901: Acquire operational parameter data of the extracorporeal membrane oxygenation (ECMO) system.

[0156] In this step, once the extracorporeal membrane oxygenation (ECMO) system is set up, it can be used. First, the operating parameter data of the ECMO system is obtained so that accurate working parameter data can be determined later.

[0157] It should be noted that the operating parameter data includes at least one of the following: air flow rate data and blood flow rate data.

[0158] The gas flow data includes at least one of gas flow detection data and gas flow correlation data. The gas flow correlation data is used to characterize the flow rate of gas flowing into the oxygenator.

[0159] Gas flow rate data can be obtained through a gas flow sensor installed between the oxygenator and the gas source equipment. The gas flow sensor can be connected to control equipment, which can then obtain the gas flow rate data by detecting the gas flow rate.

[0160] The gas source equipment includes a gas flow regulating unit, and the associated gas flow data includes the corresponding operating parameter data of the gas flow regulating unit. The control equipment can be connected to the gas flow regulating unit and can directly obtain the corresponding operating parameter data. The operating parameter data corresponding to the gas flow regulating unit can be valve opening data.

[0161] Blood flow data includes at least one of blood flow detection data and blood flow correlation data. Blood flow correlation data is used to characterize blood flow in the circulatory loop. Blood flow correlation data includes at least one of blood pump speed, blood pump current value, and blood pump differential pressure data.

[0162] Blood flow data can be obtained through a liquid flow sensor installed in the circulation loop. The liquid flow sensor can be connected to a control device, which can then obtain the blood flow data via the sensor. The control device is connected to the blood pump, thus acquiring data such as pump speed, pump current, and pump differential pressure. The pump differential pressure data can be the pressure difference before and after the pump, such as the pressure difference between the pump inlet and outlet.

[0163] It should be noted that the gas flow regulation unit in the gas source equipment can be connected to the control equipment, and the control equipment can control the gas flow regulation unit to regulate the gas flow rate output by the gas source equipment.

[0164] S902: Determine the operating parameter data corresponding to the gas temperature and humidity control unit based on the operating parameter data.

[0165] In this step, after obtaining the operating parameter data, since the correspondence between the operating parameter data and the working parameter data is stored, the working parameter data corresponding to the operating parameter data can be determined. This working parameter data is the working data corresponding to the gas temperature and humidity control unit.

[0166] It should be noted that, based on the above embodiments, experiments using an extracorporeal membrane oxygenation (ECMO) system can obtain the correspondence between operating parameter data and working parameter data. This correspondence can then be stored in the control device, which can then obtain the correspondence between parameter data and working parameter data.

[0167] It should be noted that the correspondence between operating parameter data and working parameter data can be: a correspondence between air flow detection data and working parameter data, a correspondence between air flow correlation data and working parameter data, a correspondence between valve opening data and working parameter data, a correspondence between blood flow detection data and working parameter data, a correspondence between blood flow correlation data and working parameter data, a correspondence between blood pump speed and working parameter data, a correspondence between blood pump current value and working parameter data, or a correspondence between blood pump differential pressure data and working parameter data; it can also be: a correspondence between at least one of the following: air flow detection data, air flow correlation data, blood flow detection data, blood pump speed, blood pump current value, and blood pump differential pressure data, and working parameter data, etc. This application does not limit the correspondence between operating parameter data and working parameter data, and it can be determined according to the actual situation.

[0168] S903: Based on operating parameter data, control the operation of the gas temperature and humidity regulating unit to make the gas reach the target temperature and humidity.

[0169] In this step, after determining the operating parameter data, the gas temperature and humidity regulating unit can be controlled based on the operating parameter data. When the gas output from the gas source equipment passes through the gas temperature and humidity regulating unit, the gas temperature and humidity regulating unit adjusts the temperature and humidity of the gas so that the gas flowing into the oxygenator reaches the target temperature and humidity, which corresponds to the operating parameter data.

[0170] Optionally, the aforementioned operating parameter data includes control parameter data for the first infusion component, such as infusion direction, infusion duration, and infusion volume, used to control the amount of water in the preset liquid in the gas washing device. For example, when gas humidification is not required, the first infusion component is controlled to extract the preset liquid from the gas washing device; when humidification is required, the first infusion component is controlled to input the preset liquid into the gas washing device.

[0171] Optionally, the aforementioned operating parameter data includes control parameter data of the first temperature control device, such as heating power, heating temperature, heating duration, and heat preservation duration, which are used to control the temperature of the preset liquid in the gas washing device and indirectly control the temperature of the gas.

[0172] The target temperature and humidity can be preset temperature and humidity values ​​or preset temperature and humidity states, such as heating, no heating, humidification, no humidification, etc.

[0173] It should be noted that the gas temperature and humidity control unit operates within a preset working range, ensuring that the temperature of the gas flowing into the oxygenator is within the preset temperature range and the humidity is within the target humidity range, thus preventing hemolysis. It should also be noted that when the working parameters are determined based on the correspondence between gas flow rate data and operating parameter data, the target temperature and humidity are the temperatures and humidity levels that the gas should reach to prevent blood dehydration under that gas flow rate.

[0174] The control method for the extracorporeal membrane oxygenation (ECMO) system provided in this embodiment determines the operating parameter data of the gas temperature and humidity regulation unit after acquiring the operating parameter data of the ECMO equipment. Based on this operating parameter data, the gas temperature and humidity regulation unit is controlled to achieve the target temperature and humidity for the gas. This solution determines the operating parameter data through the operating parameter data to ensure that the gas flowing into the oxygenator reaches the target temperature and humidity, making the adjustment of the water content of the target object more accurate and reducing the amount of water lost from the blood in the extracorporeal circulation loop. Furthermore, when using the control method for the ECMO system provided in this embodiment for testing, it can solve the problem of inaccurate detection of the hemolysis index due to water loss, effectively improving the accuracy of the obtained hemolysis index and thus improving the accuracy of the test results.

[0175] In addition, since the above ECMO operating parameter data is real-time, it can always be ensured that the gas temperature and humidity control unit operates according to the corresponding operating parameter data, thereby adjusting the gas temperature and humidity in real time and minimizing the blood water loss during the oxygenator gas exchange process.

[0176] Figure 10 This is a flowchart illustrating a second embodiment of the control method for the extracorporeal membrane oxygenation (ECMO) system provided in this application. Based on the above embodiments, this application describes an alarm mechanism that triggers when the temperature of the gas flowing into the oxygenator is abnormal. Figure 10 As shown, the control method of this extracorporeal membrane oxygenation system specifically includes the following steps:

[0177] S1001: Obtain temperature data of the gas flowing into the oxygenator.

[0178] During this step, while using the extracorporeal membrane oxygenation (ECMO) system, the control equipment will also acquire real-time temperature data of the gas flowing into the oxygenator to determine if the temperature is abnormal.

[0179] S1002: If the gas temperature data is outside the preset temperature range, output gas temperature alarm information.

[0180] In this step, after obtaining the gas temperature data, it is necessary to determine whether the gas temperature data is outside the preset temperature range; if the gas temperature data is outside the preset temperature range, it indicates that the temperature is abnormal, and a gas temperature alarm message is output.

[0181] The preset temperature range in this embodiment is designed to prevent both blood dehydration and hemolysis. The safe temperature range for inactivation is not limited in this embodiment and can be set according to actual conditions. For example, based on the above embodiment, during experiments using an extracorporeal membrane oxygenation (ECMO) system, when the gas temperature and humidity control unit operates with the third working parameter, it can humidify and heat the gas flowing into the oxygenator, ensuring that the gas temperature is the same as the blood temperature. At this point, the gas temperature is within the preset temperature range, thus preventing both blood dehydration and hemolysis.

[0182] The control method for the extracorporeal membrane oxygenation (ECMO) system provided in this embodiment can effectively improve the safety of the ECMO system and the target object by triggering an alarm when the temperature of the gas flowing into the oxygenator is abnormal.

[0183] Figure 11 This is a flowchart illustrating a third embodiment of the control method for the extracorporeal membrane oxygenation (ECMO) system provided in this application. Based on the above embodiments, this application describes an alarm mechanism that activates when the humidity of the gas flowing into the oxygenator is abnormal. Figure 11 As shown, the control method of this extracorporeal membrane oxygenation system specifically includes the following steps:

[0184] S1101: Obtain humidity data of the gas flowing into the oxygenator.

[0185] During this step, while using the extracorporeal membrane oxygenation (ECMO) system, the control equipment will also acquire real-time humidity data of the gas flowing into the oxygenator to determine if the humidity is abnormal and to ensure the safety of the target.

[0186] S1102: If the humidity data is outside the target humidity range, output a preset alarm message.

[0187] In this step, after obtaining the humidity data, it is necessary to determine whether the humidity data is outside the target humidity range. If the humidity data is outside the target humidity range, it indicates that the humidity is abnormal, and a gas temperature alarm message is output. The preset alarm message is used to indicate the risk of water loss or abnormal gas humidity of the target object.

[0188] It should be noted that the target humidity range is determined based on the operating parameter data. Since the control equipment also stores the correspondence between the operating parameter data and the preset humidity range, the preset humidity range corresponding to the operating parameter data can be determined first, and then the preset humidity range can be determined as the target humidity range.

[0189] It should be noted that the preset humidity range in this application embodiment is a safe humidity range that avoids blood moisture loss and hemolysis. This application embodiment does not limit the preset humidity range, which can be determined according to the actual situation.

[0190] The control method for the extracorporeal membrane oxygenation (ECMO) system provided in this embodiment can effectively improve the safety of the ECMO system and the target object by triggering an alarm when the humidity of the gas flowing into the oxygenator is abnormal.

[0191] Figure 12 This is a flowchart illustrating a fourth embodiment of the control method for the extracorporeal membrane oxygenation (ECMO) system provided in this application. Based on the above embodiments, this application further describes how the control device can determine operating parameter data based on the acquired patient treatment strategy and combined with operational parameter data. For example... Figure 12 As shown, the control method of this extracorporeal membrane oxygenation system specifically includes the following steps:

[0192] S1201: Obtain the patient treatment strategy corresponding to the control device.

[0193] In this step, when the extracorporeal membrane oxygenation system is used to treat patients, in order to ensure that the operating parameter data corresponding to the determined gas temperature and humidity regulation unit is more accurate, it is also necessary to obtain the patient treatment strategy corresponding to the control device.

[0194] It should be noted that the patient treatment strategy can be obtained in several ways: the user inputs the patient treatment strategy into the control device, and the control device then acquires the patient treatment strategy; the control device may have multiple preset patient treatment strategies for selection, from which the user chooses one, and the control device then acquires the selected patient treatment strategy; or the user may use a third-party device to send the patient treatment strategy to the control device. This application does not limit the method of obtaining the patient treatment strategy and can be determined according to the actual situation.

[0195] The aforementioned patient treatment strategies can also be understood as control strategies or control modes for control equipment.

[0196] S1202: Determine the operating parameter data corresponding to the gas temperature and humidity control unit based on the operating parameter data and the patient treatment strategy.

[0197] In this step, after the control device acquires the patient treatment strategy, since different patient treatment strategies correspond to different correspondence groups, and each correspondence group contains the correspondence between operating parameter data and working parameter data, the corresponding correspondence group can be determined based on the acquired patient treatment strategy. Then, based on the correspondence group and the operating parameter data, the working parameter data that the operating parameter data should correspond to under the above patient treatment strategy can be determined.

[0198] Furthermore, based on the working parameter data, the gas temperature and humidity regulating unit can be controlled to operate. When the gas output from the gas source equipment passes through the gas temperature and humidity regulating unit, the gas temperature and humidity regulating unit regulates the temperature and humidity of the gas, so that the gas flowing into the oxygenator reaches the target temperature and humidity. The target temperature and humidity are the target values ​​of temperature and humidity corresponding to the operating parameter data under the patient treatment strategy.

[0199] For example, if the patient's treatment strategy indicates that the patient does not need to consider blood water loss, the gas temperature and humidity control unit will not heat or humidify the gas when operating according to the corresponding parameters under the patient's treatment strategy. Alternatively, if the patient's treatment strategy indicates that the patient needs to remove some blood water, the gas temperature and humidity control unit will also not heat or humidify the gas when operating according to the corresponding parameters, thus allowing the gas to remove some moisture during gas exchange. If the patient's treatment strategy indicates that the patient only needs to consider a certain degree of blood water loss, the gas temperature and humidity control unit can humidify and heat the gas to a corresponding degree when operating according to the corresponding parameters. If the patient's treatment strategy indicates that the patient needs to consider blood water flow, the gas temperature and humidity control unit will humidify and heat the gas when operating according to the corresponding parameters to avoid blood water loss.

[0200] The control method for the extracorporeal membrane oxygenation (ECMO) system provided in this embodiment determines the operating parameter data corresponding to the gas temperature and humidity regulation unit by combining it with the patient's treatment strategy. This makes the obtained operating parameter data more accurate, and the target temperature and humidity more closely matched to the patient's condition. Furthermore, the gas temperature and humidity regulation unit operates according to the operating parameter data corresponding to the patient's treatment strategy, thereby reducing blood fluid loss.

[0201] The following are embodiments of the apparatus described in this application, which can be used to execute the embodiments of the method described in this application. For details not disclosed in the apparatus embodiments of this application, please refer to the embodiments of the method described in this application.

[0202] Figure 13 This is a schematic diagram of the structure of an embodiment of the control device for the extracorporeal membrane oxygenation system provided in this application; as shown below. Figure 13 As shown, the control device 1300 of the extracorporeal membrane oxygenation system includes:

[0203] The acquisition module 1301 is used to acquire the operating parameter data of the extracorporeal membrane oxygenation system;

[0204] Processing module 1302 is used to determine the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data;

[0205] The control module 1303 is used to control the gas temperature and humidity regulating unit to operate based on the operating parameter data, so that the gas reaches the target temperature and humidity, the target temperature and humidity corresponding to the operating parameter data.

[0206] Furthermore, the gas flow data includes at least one of gas flow detection data and gas flow correlation data, wherein the gas flow correlation data is used to characterize the gas flow rate.

[0207] Furthermore, the gas source device includes a gas flow regulating unit, and the gas flow associated data includes the operating parameter data corresponding to the gas flow regulating unit.

[0208] Furthermore, the blood flow data includes at least one of blood flow detection data and blood flow correlation data, wherein the blood flow correlation data is used to characterize the blood flow in the circulatory loop.

[0209] Furthermore, the blood flow-related data includes at least one of the following: blood pump rotation speed, blood pump current value, and blood pump differential pressure data.

[0210] Furthermore, the acquisition module 1301 is also used to acquire temperature data of the gas flowing into the oxygenator;

[0211] The output module 1304 is used to output gas temperature alarm information if the temperature data of the gas is outside the preset temperature range.

[0212] Furthermore, the acquisition module 1301 is also used to acquire humidity data of the gas flowing into the oxygenator;

[0213] Furthermore, the output module 1304 is also used to output preset alarm information if the humidity data is outside the target humidity range, the preset alarm information being used to indicate the risk of water loss or abnormal gas humidity of the target object.

[0214] Furthermore, the processing module 1302 is also used for:

[0215] Determine the preset humidity range corresponding to the operating parameter data;

[0216] The preset humidity range is determined as the target humidity range.

[0217] Furthermore, the acquisition module 1301 is also used to acquire the patient treatment strategy corresponding to the control device;

[0218] Furthermore, the processing module 1302 is specifically used to determine the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data and the patient treatment strategy; the target temperature and humidity are the target temperature and humidity values ​​corresponding to the operating parameter data under the patient treatment strategy.

[0219] The control device for the extracorporeal membrane oxygenation system provided in this embodiment is used to execute the technical solution in any of the aforementioned method embodiments. Its implementation principle and technical effect are similar, and will not be described again here.

[0220] Figure 14 This is a schematic diagram of the structure of an electronic device provided in this application. Figure 14 As shown, the electronic device 1400 includes:

[0221] Processor 1401, memory 1402, and communication interface 1403;

[0222] The memory 1402 is used to store the executable instructions of the processor 1401;

[0223] The processor 1401 is configured to execute the technical solutions in any of the foregoing method embodiments by executing the executable instructions.

[0224] Optionally, the memory 1402 can be either standalone or integrated with the processor 1401.

[0225] Optionally, when the memory 1402 is a device independent of the processor 1401, the electronic device 1400 may further include:

[0226] Bus 1404, memory 1402 and communication interface 1403 are connected to processor 1401 through bus 1404 and complete communication with each other. Communication interface 1403 is used to communicate with other devices.

[0227] Optionally, the communication interface 1403 can be implemented using a transceiver. The communication interface is used to enable communication between the database access device and other devices (e.g., clients, read-write databases, and read-only databases). The memory may include random access memory (RAM) and may also include non-volatile memory, such as at least one disk drive.

[0228] Bus 1404 can be a Peripheral Component Interconnect (PCI) bus or an Extended Industry Standard Architecture (EISA) bus, etc. Buses can be categorized as address buses, data buses, control buses, etc. For ease of representation, only one thick line is used in the diagram, but this does not indicate that there is only one bus or one type of bus.

[0229] The processors mentioned above can be general-purpose processors, including central processing units (CPUs), network processors (NPs), etc.; they can also be digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, or discrete hardware components.

[0230] The electronic device is used to execute the technical solutions in any of the foregoing method embodiments. Its implementation principle and technical effect are similar, and will not be described again here.

[0231] This application also provides a readable storage medium storing a computer program thereon, which, when executed by a processor, implements the technical solutions provided in any of the foregoing method embodiments.

[0232] This application also provides a computer program product, including a computer program, which, when executed by a processor, is used to implement the technical solutions provided in any of the foregoing method embodiments.

[0233] Those skilled in the art will understand that all or part of the steps of the above-described method embodiments can be implemented by hardware related to program instructions. The aforementioned program can be stored in a computer-readable storage medium. When executed, the program performs the steps of the above-described method embodiments; and the aforementioned storage medium includes various media capable of storing program code, such as ROM, RAM, magnetic disks, or optical disks.

[0234] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. An extracorporeal membrane oxygenation (ECMO) system, characterized in that, The extracorporeal membrane oxygenation system includes: an oxygenator, a blood pump, a gas temperature and humidity control unit, a gas source device, and a control device; The blood pump is connected to the oxygenator, and the blood pump, the oxygenator, and the target object are connected to form a circulation loop; The oxygenator is connected to the gas source device, and the gas temperature and humidity regulating unit is disposed in the connection path between the oxygenator and the gas source device. The gas temperature and humidity regulating unit is used to regulate the temperature and humidity of the gas flowing into the oxygenator. The control device is connected to the blood pump and the gas temperature and humidity regulating unit, respectively. The control device is used to control the operation of the gas temperature and humidity regulating unit so that the gas reaches the target temperature and humidity. The target temperature and humidity correspond to the operating parameter data of the extracorporeal membrane oxygenation system. The operating parameter data includes at least one of gas flow rate data and blood flow rate data. The target temperature and humidity are the target temperature and humidity values ​​corresponding to the operating parameter data.

2. The extracorporeal membrane oxygenation system according to claim 1, characterized in that, The gas temperature and humidity regulating unit includes a gas washing device and a first temperature control device; The gas outlet of the gas source device is connected to the gas inlet of the gas scrubbing device, the gas outlet of the gas scrubbing device is connected to the gas inlet of the oxygenator, and the gas scrubbing device stores a preset liquid, which is used to humidify the gas entering the gas scrubbing device. The gas washing device is disposed in the accommodating cavity of the first temperature control device, which is used to regulate the temperature of the preset liquid.

3. The extracorporeal membrane oxygenation system according to claim 2, characterized in that, The gas washing device also includes a liquid delivery interface, and the gas temperature and humidity regulating unit also includes a first liquid delivery component. The first liquid delivery component is connected to the liquid delivery interface and is used to replenish or extract the preset liquid.

4. The extracorporeal membrane oxygenation system according to claim 1, characterized in that, The target object includes a blood storage device, and the extracorporeal membrane oxygenation system further includes a second temperature control device. The second temperature control device includes a temperature-controlled accommodating cavity for accommodating the blood storage device, and the second temperature control device is used to control the temperature of the blood in the blood storage device.

5. The extracorporeal membrane oxygenation system according to claim 4, characterized in that, The blood storage device includes a liquid bag, and the extracorporeal membrane oxygenation system further includes a container corresponding to the liquid bag, wherein the liquid bag is placed in the liquid contained in the container, and the container is provided with a liquid level scale, which is used to indicate the change in the volume of liquid in the liquid bag.

6. The extracorporeal membrane oxygenation system according to claim 5, characterized in that, The extracorporeal membrane oxygenation system further includes a liquid level detection unit, which is used to detect the water level of the liquid in the container.

7. The extracorporeal membrane oxygenation system according to any one of claims 1 to 6, characterized in that, The extracorporeal membrane oxygenation system further includes a second infusion assembly for delivering fluid to the target object.

8. The extracorporeal membrane oxygenation system according to claim 7, characterized in that, The control device is used to control the operation of the second infusion assembly to deliver liquid to the target object.

9. A control device for an extracorporeal membrane oxygenation (ECMO) system, characterized in that, Installed in the extracorporeal membrane oxygenation system according to any one of claims 1 to 8, the device comprises: The acquisition module is used to acquire the operating parameter data of the extracorporeal membrane oxygenation system; The processing module is used to determine the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data. The control module is used to control the gas temperature and humidity regulating unit to operate based on the operating parameter data, so that the gas reaches the target temperature and humidity, which corresponds to the operating parameter data.

10. The apparatus according to claim 9, characterized in that, The gas flow data includes at least one of gas flow detection data and gas flow correlation data, wherein the gas flow correlation data is used to characterize the flow rate of the gas.

11. The apparatus according to claim 10, characterized in that, The gas source device includes a gas flow regulating unit, and the gas flow associated data includes the operating parameter data corresponding to the gas flow regulating unit.

12. The apparatus according to claim 9, characterized in that, The blood flow data includes at least one of blood flow detection data and blood flow correlation data, wherein the blood flow correlation data is used to characterize the blood flow in the circulatory loop.

13. The apparatus according to claim 12, characterized in that, The blood flow-related data includes at least one of the following: blood pump speed, blood pump current value, and blood pump differential pressure data.

14. The apparatus according to claim 9, characterized in that, The acquisition module is also used to acquire temperature data of the gas flowing into the oxygenator; The device also includes an output module, which is used to output a gas temperature alarm message if the temperature data of the gas is outside a preset temperature range.

15. The apparatus according to claim 14, characterized in that, The acquisition module is also used to acquire humidity data of the gas flowing into the oxygenator; The output module is also used to output a preset alarm message if the humidity data is outside the target humidity range. The preset alarm message is used to indicate the risk of water loss or abnormal gas humidity of the target object.

16. The apparatus according to claim 9, characterized in that, The acquisition module is also used to acquire the patient treatment strategy corresponding to the control device; The processing module is further configured to determine the operating parameter data corresponding to the gas temperature and humidity regulating unit based on the operating parameter data and the patient treatment strategy. The target temperature and humidity are the target values ​​corresponding to the operating parameter data under the patient treatment strategy.

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