A lightweight high-throughput sterilization transfer device and method for an experimental animal facility

Abstract

The application discloses a light-weight large-flux sterilization transfer device and method for experimental animal facilities, and belongs to the technical field of disinfection and sterilization transfer, which comprises a sterilization cabin, a loading cabin and an unloading cabin, and the loading cabin and the unloading cabin are arranged on the two sides of the sterilization cabin respectively; the sterilization cabin comprises a plastic film and a supporting frame, and the inside of the supporting frame is provided with a circulating pipeline. The application has the beneficial effects that: the supporting frame and the airtight plastic film are adopted to construct the sterilization cabin, a large flexible light-weight airtight space is formed, the device is light and easy to assemble, the vaporized hydrogen peroxide pipe is injected into the heat-insulating circulating pipeline of the supporting frame, the heat loss of the vaporized hydrogen peroxide pipe can be avoided, the vaporized hydrogen peroxide can uniformly act on the surface of the object at a stable concentration through the setting of the air inlet hole and the air return hole in the sterilization cabin, the air exchange efficiency is improved, the sterilization effect is improved, and then the vaporized hydrogen peroxide which is not fully reacted can be returned through the circulating pipeline, so that the rapid circulation is realized.

Description

Technical Field

[0001] This invention relates to the field of disinfection and sterilization transfer technology, and more specifically, to a lightweight, high-throughput sterilization transfer device and method for laboratory animal facilities. Background Technology

[0002] With the promulgation of the "Biosafety Law of the People's Republic of China," the biosafety of laboratory animals, which involves public safety, has become a top priority in the administrative licensing management of laboratory animals. Effective control of exogenous pathogens contaminating laboratory animals is particularly important in laboratory animal biosafety work. Microbiological control of laboratory animal quality involves the control of zoonotic pathogens and opportunistic pathogens. These pathogens not only affect the accuracy and reproducibility of animal experimental results, but some can also cause infection, illness, and even death in animals and laboratory personnel. Therefore, strictly controlling exogenous pathogens in laboratory animal facilities is crucial to ensuring the quality of laboratory animals.

[0003] The concept of vaporized hydrogen peroxide sterilization was proposed around 1980 to 1990. Due to its advantages such as low energy consumption, high efficiency, and low cost, it has been widely used in various fields such as food packaging, medical care, biological purification, and environmental protection after more than 30 years of development. At the same time, with the increasing prominence of food safety and environmental protection issues, as a green and environmentally friendly sterilizing agent, vaporized hydrogen peroxide sterilization has enormous development potential and is often used for sterilization and disinfection of laboratory animal facilities.

[0004] Currently, the commonly used pollution control equipment in laboratory animal facilities are mainly double-door steam autoclaves and transfer windows. Although the former has a reliable sterilization effect, it is a special equipment, which is complicated to manage and has a large operating load, and has special requirements for the building structure. The latter is simple to operate, but the disinfection effect is unstable. Moreover, the existing technology lacks a lightweight, efficient and uniform transfer device, and vaporized hydrogen peroxide is prone to liquefaction during use, which affects the disinfection effect. Summary of the Invention

[0005] To overcome the shortcomings of existing technologies in laboratory animal facilities, which primarily utilize double-door autoclaves and transfer windows for pollution control, this invention provides a lightweight, high-throughput sterilization transfer device for laboratory animal facilities. The device comprises a sterilization chamber, a loading chamber, and an unloading chamber, with the loading chamber and unloading chamber located on opposite sides of the sterilization chamber. The sterilization chamber includes a plastic film and a supporting frame. The plastic film is made of airtight, transparent PVC soft plastic material. While the former provides reliable sterilization, it is specialized equipment with complex management requirements, demanding heavy loads and specific structural requirements for building structures. The latter is simple to operate but has inconsistent disinfection effects. Furthermore, existing technologies lack lightweight, efficient, and uniform transfer devices, and vaporized hydrogen peroxide is prone to liquefaction during use, affecting disinfection efficiency. A plastic film is laid on the outer surface of the support frame. The support frame contains a heat-insulating non-metallic circulation pipe. The air inlet of the circulation pipe is located at the top of the support frame and connected to several air inlets for discharging disinfectant gas. The air outlet of the circulation pipe is located below the side opposite to the air inlets and connected to several air return holes for recovering disinfectant gas. Both the air inlets and air return holes are inclined towards the center of the sterilization chamber. The loading chamber has external air inlets and external air return ports on its side walls, respectively. These ports are connected to the circulation pipe via air inlets and air return pipes located at the top and bottom of the loading chamber. Both the loading chamber and the unloading chamber are equipped with airtight doors.

[0006] The sterilization chamber is constructed using a supporting frame and plastic film, forming a large, flexible, lightweight, and airtight space. This makes the device lightweight and easy to assemble. Vaporized hydrogen peroxide is injected into the insulated circulation pipe inside the sterilization chamber through the air inlet pipe of the loading chamber. This prevents the vaporized hydrogen peroxide from turning into liquid due to heat loss. The air inlet and outlet ports inside the sterilization chamber allow the vaporized hydrogen peroxide to act on the object surface at a stable concentration and evenly, improving air exchange efficiency and thus enhancing the sterilization effect. At the same time, unreacted vaporized hydrogen peroxide can return to the sterilization chamber through the circulation pipe and the continuously injected vaporized hydrogen peroxide, achieving rapid hydrogen peroxide circulation. This greatly improves the disinfection efficiency of the device and ensures the uniformity of disinfection for large volumes of items.

[0007] Preferably, the external air inlet and external air return ports are connected to hydrogen peroxide generators, and the external air inlet and external air return ports are respectively connected to high-efficiency filters. The two high-efficiency filters are installed vertically on the side walls inside the loading compartment and are respectively connected to the air inlet pipe and the air return pipe. The external air inlet and external air return ports are respectively provided with switch butterfly valves.

[0008] By installing high-efficiency filters on the hydrogen peroxide disinfection gas inlet and outlet pipelines, impurities can be filtered out, preventing them from entering the sterilization chamber and further ensuring the sterile environment of the sterilization chamber.

[0009] Preferably, the top of the support frame has a plurality of air inlets evenly distributed thereon, and the bottom of the support frame has a plurality of air return holes evenly distributed thereon below the side opposite to the plurality of air inlets. The circulation pipe is connected to the air inlet pipe and the air return pipe through the air inlet CF interface and the air return CF interface, respectively.

[0010] Preferably, the front of the loading compartment and the unloading compartment are respectively hinged to the airtight doors by two adjustable hinges, and the two airtight doors are respectively provided with sealing plates and tempered glass windows.

[0011] Preferably, the support frame, loading compartment and unloading compartment are all made of stainless steel, and the surfaces of the loading compartment and the unloading compartment are respectively provided with detection interfaces.

[0012] Multiple detection interfaces are installed on the loading and unloading chambers, which facilitates the connection of external detection equipment by staff to monitor data such as air pressure, temperature and hydrogen peroxide concentration inside the sterilization chamber, thereby facilitating the management and monitoring of the device during operation.

[0013] Preferably, the bottom of the sterilization chamber is provided with a pad, and two auxiliary ramps for getting on and off the vehicle are respectively connected to the two sides of the pad located directly below the loading chamber and the unloading chamber.

[0014] Preferably, each of the two airtight doors has a door handle on the side away from the adjustable hinge, and each of the outer surfaces of the two airtight doors has a plurality of eccentric shaft clamping assemblies.

[0015] Preferably, the eccentric shaft clamping assembly includes an eccentric shaft pin, a pin seat, a connecting seat, a groove, and a pin handle. The eccentric shaft pin is movably installed in the pin seat. A groove is formed on the pin seat, and a pin handle for connecting the eccentric shaft pin is inserted into the groove. The movable end of the eccentric shaft pin matches the connecting seat provided on the loading compartment and the unloading compartment.

[0016] Preferably, a waste liquid discharge port is provided at the bottom of the sterilization chamber near the loading chamber.

[0017] The present invention also provides a method comprising the following steps:

[0018] Step 1: Open the loading chamber and send a large number of items to be processed for the laboratory animal facility into the sterilization chamber. Place them on the shelves, arrange them properly, and strictly prohibit overlapping and squeezing. Then lock the loading chamber.

[0019] Step 2: Start the hydrogen peroxide generator in circulation mode, so that the hydrogen peroxide is vaporized and filtered through the high-efficiency filter before entering the circulation pipe in the support frame through the air inlet pipe. With the entry of hydrogen peroxide gas, the air pressure in the sterilization chamber reaches more than 100Pa compared to the outside, which meets the sterilization environment requirements.

[0020] Step 3: Vaporized hydrogen peroxide enters the sterilization chamber through multiple air inlets on the support frame to sterilize the surface of the items. Under the space maintained by the airtight plastic film, the vaporized hydrogen peroxide disinfectant gas undergoes effective airflow organization, and the gas exchange efficiency of hydrogen peroxide gas in the sterilization chamber reaches more than 90%, thereby ensuring that the hydrogen peroxide gas is evenly distributed and has a stable concentration on the surface of the objects.

[0021] Step 4: Under the continuous action of the hydrogen peroxide generator, the unreacted vaporized hydrogen peroxide disinfection gas in the sterilization chamber enters the circulation pipeline through multiple return air holes on the support frame and returns to the hydrogen peroxide generator for circulation.

[0022] Step 5: Under the cyclical disinfection treatment of vaporized hydrogen peroxide, the items are thoroughly disinfected.

[0023] Step Six: After sterilization is completed, verify the sterilization indicator tape. Once sterilization is deemed successful, open the unloading chamber and remove the sterilized items intended for the laboratory animal facility.

[0024] The items to be disinfected are placed in the loading chamber and removed through the unloading chamber after disinfection. The operation is simple and convenient, effectively reducing the biosafety risks of laboratory animal facilities and ensuring the quality of laboratory animals.

[0025] Beneficial effects:

[0026] The beneficial effects of adopting the technical solution of this invention are as follows:

[0027] (1) The sterilization chamber is constructed using a support frame and plastic film, forming a large, flexible, lightweight, and airtight space. This makes the device lightweight and easy to assemble, increases the sterilization throughput, and overcomes the cumbersome installation requirements of special pressure vessels. The vaporized hydrogen peroxide is injected into the insulated circulation pipe inside the sterilization chamber through the air inlet pipe of the loading chamber, which can prevent the vaporized hydrogen peroxide from turning into liquid due to heat loss. Through the setting of the air inlet and return holes inside the sterilization chamber, the vaporized hydrogen peroxide can act on the surface of the object at a stable concentration and uniformly, and improve the air exchange efficiency, thereby improving the sterilization effect. At the same time, the unreacted vaporized hydrogen peroxide can return to the sterilization chamber through the circulation pipe and the continuously injected vaporized hydrogen peroxide, realizing the rapid circulation of hydrogen peroxide, which greatly improves the disinfection efficiency of the device and ensures the uniformity of disinfection of large-volume items. This invention is the first to combine vaporized hydrogen peroxide sterilization technology with lightweight, airtight, and large-space aerodynamics to achieve efficient sterilization of the surface of items.

[0028] (2) A high-efficiency filter is installed on the hydrogen peroxide disinfection gas inlet and outlet pipeline to filter it, prevent impurities from entering the sterilization chamber, and further ensure the sterile environment of the sterilization chamber.

[0029] (3) The items to be disinfected are placed in the loading chamber and removed through the unloading chamber after disinfection. The operation is simple and convenient, and a large disinfection space can be formed, which greatly increases the disinfection loading capacity, effectively reduces the biosafety risk of experimental animal facilities, and ensures the quality of experimental animals.

[0030] (4) Through multiple detection interfaces set on the loading and unloading chambers, it is convenient for staff to connect external detection equipment and monitor data such as air pressure, temperature and hydrogen peroxide concentration inside the sterilization chamber, thereby facilitating the management and monitoring of the device during operation. Attached Figure Description

[0031] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present invention and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained from these drawings without creative effort.

[0032] Figure 1 This is a schematic diagram of the overall structure of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0033] Figure 2 This is a schematic diagram of the internal structure of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0034] Figure 3 This is a schematic diagram of the connection structure of the loading compartment of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0035] Figure 4 This is a schematic diagram of the interior of the loading chamber of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0036] Figure 5 This is a schematic diagram of the waste liquid discharge port of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention;

[0037] Figure 6 This is a schematic diagram of the supporting frame of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention;

[0038] Figure 7 This is a schematic diagram of the front of the loading compartment of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0039] Figure 8 This is a schematic diagram of the adjustable hinge structure of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention;

[0040] Figure 9 This is a schematic diagram of the eccentric shaft clamping assembly of the lightweight, high-throughput disinfection and sterilization transfer device of the present invention.

[0041] In the diagram: 1. Sterilization chamber; 2. Loading chamber; 3. Airtight door; 4. Plastic film; 5. Assistive ramp for getting on and off; 6. Detection interface; 7. Support frame; 8. High-efficiency filter; 9. Pad; 10. Air inlet pipe; 11. Butterfly valve; 12. External air inlet interface; 13. External air return interface; 14. Sealing plate; 15. Adjustable hinge; 16. Tempered glass window; 17. Door handle; 18. Air return pipe; 19. Waste liquid discharge port; 20. Air return hole; 21. Air inlet hole; 22. Unloading chamber; 23. Eccentric shaft clamping assembly; 24. Eccentric shaft pin; 25. Pin seat; 26. Connecting seat; 27. Inclined groove; 28. Pin handle. Detailed Implementation

[0042] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, not all of them. Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to represent selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0043] This embodiment uses a supporting frame and plastic film to construct the sterilization chamber, forming a large, flexible, lightweight, and airtight space. This also makes the device lightweight and easy to assemble. Vaporized hydrogen peroxide is injected into the sterilization chamber through the air inlet pipe of the loading chamber. Through effective airflow organization, the vaporized hydrogen peroxide can act on the object surface at a stable concentration and uniformly, thereby improving the sterilization effect. Afterwards, the vaporized hydrogen peroxide can be returned through a circulation pipe, achieving rapid circulation of hydrogen peroxide and further improving the sterilization efficiency of the device, ensuring the uniformity of sterilization for large-volume items. Specific implementation details are as follows:

[0044] like Figures 1 to 9 As shown, a lightweight, high-throughput sterilization transfer device for laboratory animal facilities includes a sterilization chamber 1, a loading chamber 2, and an unloading chamber 22, which are respectively located on both sides of the sterilization chamber 1. The sterilization chamber 1 includes a plastic film 4 and a support frame 7. The plastic film 4 is made of airtight, transparent PVC soft plastic material and is laid on the outer surface of the support frame 7. The support frame 7 has an insulated non-metallic circulation pipe inside, and the air inlet of the circulation pipe is located at the top of the support frame 7 and connected to several air inlets 2 for discharging sterilization gases. 1. The outlet of the circulation pipeline is located below one side of several air inlets 21 and is connected to several return air holes 20 for recovering disinfection gas. The air inlets 21 and the return air holes 20 are all inclined towards the center of the sterilization chamber 1. The loading chamber 2 has an external air inlet 12 and an external air return 13 on the upper and lower sides of its side wall, respectively. The external air inlet 12 and the external air return 13 are connected to the circulation pipeline through the air inlet pipe 10 and the return air pipe 18 set at the top and bottom of the loading chamber 2, respectively. Both the loading chamber 2 and the unloading chamber 22 are equipped with airtight doors 3. The sterilization chamber 1 is constructed using a support frame 7 and a plastic film 4, forming a large, flexible, lightweight, and airtight space. This makes the device lightweight and easy to assemble. Vaporized hydrogen peroxide is injected into the sterilization chamber 1 through the air inlet pipe 10 of the loading chamber 2 via a hydrogen peroxide generator into the insulated circulation pipe of the support frame 7. This prevents the vaporized hydrogen peroxide from condensing into liquid due to heat loss. The vertical arrangement of the air inlet 21 and return vent 20 inside the sterilization chamber 1 ensures that the vaporized hydrogen peroxide acts on the object surface at a stable concentration and uniformly, improving ventilation efficiency and thus enhancing the sterilization effect. Simultaneously, unreacted vaporized hydrogen peroxide can return to the sterilization chamber 1 through the circulation pipe and the continuously injected vaporized hydrogen peroxide, achieving rapid hydrogen peroxide circulation. This significantly improves the disinfection efficiency of the device and ensures the uniformity of disinfection for large volumes of items.

[0045] The external air inlet 12 and the external air return 13 are connected to hydrogen peroxide generators. The external air inlet 12 and the external air return 13 are respectively connected to high-efficiency filters 8. The two high-efficiency filters 8 are installed vertically on the side wall inside the loading chamber 2 and are respectively connected to the air inlet pipe 10 and the air return pipe 18. The external air inlet 12 and the external air return 13 are respectively provided with switch butterfly valves 11. The high-efficiency filters 8 are installed on the hydrogen peroxide disinfection gas inlet and outlet pipes to filter it and prevent impurities from entering the sterilization chamber 1, thereby further ensuring the sterile environment of the sterilization chamber 1. The entry and exit of hydrogen peroxide disinfection gas can be controlled by the switch butterfly valves 11.

[0046] The top of the support frame 7 has several air inlets 21 evenly distributed, and the bottom of the support frame 7 has several air return holes 20 evenly distributed below the side opposite to the air inlets 21. The circulation pipe is connected to the air inlet pipe 10 and the air return pipe 18 through the air inlet CF interface and the air return CF interface, respectively. Through the air inlets 21, the disinfection gas can be evenly discharged into the sterilization chamber 1. Through the air return holes 20, the disinfection gas can be fully recovered. The air return holes 20 and the air inlets 21 are located on opposite sides, which facilitates the circulation of disinfection gas and improves the ventilation efficiency.

[0047] The loading compartment 2 and the unloading compartment 22 are respectively hinged to airtight doors 3 by two adjustable hinges 15 on their front sides. Each airtight door 3 is provided with a sealing plate 14 and a tempered glass window 16. The tempered glass of the tempered glass window 16 can be pressed and sealed. Under the action of the sealing ring, the sealing performance at the connection between the airtight door 3 and the loading compartment 2 can be improved. The sealing plate 14 on the unloading compartment 22 is a thin film pressing sealing plate 14, which can be tightly sealed with the plastic film 4.

[0048] The support frame 7, loading compartment 2 and unloading compartment 22 are all made of stainless steel, and the surfaces of loading compartment 2 and unloading compartment 22 are respectively provided with detection interfaces 6.

[0049] The bottom of the sterilization chamber 1 is equipped with a pad 9. On both sides of the pad 9, directly below the loading chamber 2 and the unloading chamber 22, there are two auxiliary ramps 5 for loading and unloading. The pad 9 can be tightly connected to the bottom frame of the support frame 7 to support the sterilization chamber 1. The two auxiliary ramps 5 facilitate the loading and unloading of items.

[0050] Each of the two airtight doors 3 has a door handle 17 on the side away from the adjustable hinge 15. Several eccentric shaft clamping assemblies 23 are provided on the outer edge of the two airtight doors 3. The door handle 17 makes it easy to open the airtight door 3. The eccentric shaft clamping assembly 23 can clamp the airtight door 3 tightly after it is closed, so that the airtight door 3 is more tightly connected to the loading compartment 2 or unloading compartment 22, which greatly improves the airtightness of the entire device.

[0051] The eccentric shaft clamping assembly 23 includes an eccentric shaft pin 24, a pin seat 25, a connecting seat 26, a groove 27, and a pin handle 28. The eccentric shaft pin 24 is movably installed in the pin seat 25. A groove 27 is formed on the pin seat 25. The pin handle 28, which connects to the eccentric shaft pin 24, is inserted into the groove 27. The movable end of the eccentric shaft pin 24 matches the connecting seat 26 provided on the loading compartment 2 and the unloading compartment 22. After the eccentric shaft pin 24 is inserted into the connecting seat 26, the pin handle 28 can be pushed to move along the groove 27 to clamp the airtight door 3.

[0052] Waste liquid discharge port 19 is provided at the bottom of the sterilization chamber 1 near the loading chamber 2, which allows staff to connect external testing equipment and monitor data such as air pressure, temperature and hydrogen peroxide concentration inside the sterilization chamber 1, thereby facilitating the management and monitoring of the device during operation.

[0053] Waste liquid discharge port 19 is provided at the bottom of the sterilization chamber 1 near the loading chamber 2. Waste liquid can be discharged through the waste liquid discharge port 19.

[0054] The present invention also provides a method comprising the following steps:

[0055] Step 1: Open the loading chamber 2 and send a large number of items to be processed for the laboratory animal facility into the sterilization chamber 1, place them on the shelf, arrange them properly, and strictly prohibit overlapping and squeezing, and then lock the loading chamber 2.

[0056] Step 2: Start the circulation mode of the hydrogen peroxide generator to vaporize the hydrogen peroxide and filter it through the high-efficiency filter 8. Then, it enters the circulation pipe in the support frame 7 through the air inlet pipe 10. As the hydrogen peroxide gas enters, the air pressure in the sterilization chamber 1 reaches more than 100Pa compared to the outside, which meets the sterilization environment requirements.

[0057] Step 3: Vaporized hydrogen peroxide enters the sterilization chamber 1 through multiple air inlets 21 on the support frame 7 to sterilize the surface of the items. Under the space maintained by the airtight plastic film 4, the vaporized hydrogen peroxide disinfectant gas undergoes effective airflow organization, and the gas exchange efficiency of hydrogen peroxide gas in the sterilization chamber 1 reaches more than 90%, thereby ensuring that the hydrogen peroxide gas is evenly distributed and has a stable concentration on the surface of the objects.

[0058] Step 4: Under the continuous action of the hydrogen peroxide generator, the unreacted vaporized hydrogen peroxide disinfection gas in the sterilization chamber 1 enters the circulation pipeline through multiple return air holes 20 on the support frame 7 and returns to the hydrogen peroxide generator through the return air pipe 18 for circulation.

[0059] Step 5: Under the cyclical disinfection treatment of vaporized hydrogen peroxide, the items are thoroughly disinfected.

[0060] Step Six: After sterilization is completed, verify the sterilization indicator tape. If sterilization is qualified, open the unloading compartment 22 and take out the sterilized items for the experimental animal facility.

[0061] Working Principle: A large, flexible, lightweight, and airtight space is constructed through the combination of a support frame and a plastic film within the sterilization chamber. The hydrogen peroxide generator, once activated, injects vaporized hydrogen peroxide through the inlet pipe of the loading chamber into the insulated circulation pipe of the support frame within the sterilization chamber. This prevents the vaporized hydrogen peroxide from condensing into liquid due to heat loss. With several inlet holes on the upper part of the support frame and several return holes on the lower part, the vaporized hydrogen peroxide can be applied stably and evenly to the surface of objects, thereby improving the sterilization effect. This also makes the device lightweight and easy to assemble, with good airtightness, ensuring a stable hydrogen peroxide concentration. High-efficiency filters are installed on the hydrogen peroxide disinfection gas inlet and outlet pipes to filter the gas, preventing impurities from entering the sterilization chamber and further ensuring a sterile environment. The vaporized hydrogen peroxide can then be returned through the circulation pipe, achieving rapid hydrogen peroxide circulation. After sterilization, it can be removed through the unloading chamber. The operation is simple and convenient, with high air exchange efficiency.

[0062] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the invention by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the invention should be included within the scope of protection of the invention.

Claims

1. A lightweight, high-throughput sterilization transfer device for laboratory animal facilities, characterized in that, It includes a sterilization chamber (1), a loading chamber (2) and an unloading chamber (22), wherein the loading chamber (2) and the unloading chamber (22) are respectively disposed on both sides of the sterilization chamber (1); The sterilization chamber (1) includes a plastic film (4) and a support frame (7). The plastic film (4) is made of airtight transparent PVC soft plastic material and is laid on the outer surface of the support frame (7). The support frame (7) is provided with a heat-insulating non-metallic circulation pipe. The air inlet of the circulation pipe is located at the top of the support frame (7) and is connected to several air inlets (21) for discharging disinfection gas. The air outlet of the circulation pipe is located below the side opposite to the several air inlets (21) and is connected to several air return holes (20) for recovering disinfection gas. The several air inlets (21) and the several air return holes (20) are all inclined towards the center of the sterilization chamber (1). The loading compartment (2) is provided with an air inlet (12) and an air return (13) on the upper and lower sides of its side wall, respectively. The air inlet (12) and the air return (13) are connected to the circulation pipeline through the air inlet pipe (10) and the air return pipe (18) provided at the top and bottom of the loading compartment (2), respectively. Both the loading compartment (2) and the unloading compartment (22) are provided with airtight doors (3). The loading chamber (2) and the unloading chamber (22) are respectively provided with detection interfaces (6). Several detection interfaces (6) are provided on the loading chamber (2) and the unloading chamber (22) to facilitate the staff to connect external detection equipment and monitor data such as air pressure, temperature and hydrogen peroxide concentration inside the sterilization chamber. The external air inlet (12) and external air return (13) are connected to a hydrogen peroxide generator. The external air inlet (12) and external air return (13) are respectively connected to a high-efficiency filter (8). The two high-efficiency filters (8) are installed on the side wall inside the loading compartment (2) and are respectively connected to the air inlet pipe (10) and the air return pipe (18). The external air inlet (12) and external air return (13) are respectively provided with a switch butterfly valve (11). The hydrogen peroxide generator starts the circulation mode, so that the hydrogen peroxide is vaporized and filtered by the high-efficiency filter (8) and enters the circulation pipe in the support frame (7) through the air inlet pipe (10). As the hydrogen peroxide gas enters, the air pressure in the sterilization chamber reaches more than 100 Pa to the outside, which meets the sterilization environment requirements.

2. The lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 1, characterized in that, The top of the support frame (7) is evenly distributed with a number of air inlets (21), and the bottom of the support frame (7) is evenly distributed with a number of air return holes (20) located below the side opposite to the air inlets (21). The circulation pipe is connected to the air inlet pipe (10) and the air return pipe (18) through the air inlet CF interface and the air return CF interface, respectively.

3. The lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 1, characterized in that, The front of the loading compartment (2) and the unloading compartment (22) are respectively hinged to the airtight doors (3) by two adjustable hinges (15). The two airtight doors (3) are respectively provided with sealing plates (14) and tempered glass windows (16).

4. The lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 1, characterized in that, The bottom of the sterilization chamber (1) is provided with a pad (9), and two auxiliary ramps (5) for getting on and off the vehicle are respectively connected to the two sides of the pad (9) located directly below the loading chamber (2) and the unloading chamber (22).

5. A lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 3, characterized in that, Each of the two airtight doors (3) is provided with a door handle (17) on the side away from the adjustable hinge (15), and a number of eccentric shaft clamping assemblies (23) are provided on the edge of the outer surface of each of the two airtight doors (3).

6. The lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 5, characterized in that, The eccentric shaft clamping assembly (23) includes an eccentric shaft pin (24), a pin seat (25), a connecting seat (26), a groove (27), and a pin handle (28). The eccentric shaft pin (24) is movably installed in the pin seat (25). A groove (27) is formed on the pin seat (25). A pin handle (28) for connecting the eccentric shaft pin (24) is inserted in the groove (27). The movable end of the eccentric shaft pin (24) matches the connecting seat (26) provided on the loading compartment (2) and the unloading compartment (22).

7. The lightweight, high-throughput sterilization transfer device for laboratory animal facilities according to claim 1, characterized in that, Waste liquid discharge port (19) is provided at the bottom of the sterilization chamber (1) near the loading chamber (2).

8. A method, characterized in that, The sterilization transfer device according to any one of claims 1-7 includes the following steps: Step 1: Open the loading chamber (2) and send a large number of items to be processed for the experimental animal facility into the sterilization chamber (1), place them on the shelf, arrange them properly, and strictly prohibit overlapping and squeezing, and then lock the loading chamber (2). Step 2: Start the circulation mode of the hydrogen peroxide generator to vaporize the hydrogen peroxide and filter it through the high-efficiency filter (8). Then, it enters the circulation pipe in the support frame (7) through the air inlet pipe (10). As the hydrogen peroxide gas enters, the air pressure in the sterilization chamber (1) reaches more than 100 Pa to the outside of the chamber, which meets the sterilization environment requirements. Step 3: Vaporized hydrogen peroxide enters the sterilization chamber (1) through multiple air inlets (21) on the support frame (7) to sterilize the surface of the items. Under the space maintenance of the airtight plastic film (4), the vaporized hydrogen peroxide disinfection gas passes through the effective airflow organization, and the gas exchange efficiency of hydrogen peroxide gas in the sterilization chamber (1) reaches more than 90%, thereby ensuring that the hydrogen peroxide gas is evenly distributed and the concentration is stable on the surface of the object. Step 4: Under the continuous action of the hydrogen peroxide generator, the unreacted vaporized hydrogen peroxide disinfection gas in the sterilization chamber (1) enters the circulation pipeline through multiple return air holes (20) on the support frame (7) and returns to the hydrogen peroxide generator through the return air pipe (18) for circulation. Step 5: Under the cyclical disinfection treatment of vaporized hydrogen peroxide, the items are thoroughly disinfected; Step 6: After sterilization is completed, verify the sterilization indicator tape. After sterilization is qualified, open the unloading chamber (22) and take out the sterilized items for the experimental animal facility.

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