A multi-channel detection device and method
By using multi-channel detection circuits and integrated devices, the problems of cumbersome interface replacement and large equipment size in existing electrochemical workstations with multi-channel detection are solved, and efficient and accurate multi-channel electrode selection and data processing are achieved.
Patent Information
- Application Number
- CN202311008740.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-08-11
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2043-08-11
AI Technical Summary
Most existing electrochemical workstations are single-channel, requiring different test interfaces to achieve multi-channel testing. Furthermore, the equipment is bulky, information transmission is subject to interference, the testing methods are cumbersome, and data needs to be transmitted to a computer for output.
Design a multi-channel detection circuit, including a data acquisition unit, an interaction unit, and a carrier housing, integrating a chip electrode slot and an electrode connection unit. Through the cooperation of a processing module, a channel selection module, and a power supply module, it realizes single-channel connection to multi-channel detection, integrates the device structure, and supports multi-channel electrode selection and direct data processing in electrochemical workstations.
It enables multi-channel detection without changing the test interface, reduces equipment size, reduces information transmission interference, improves detection speed and accuracy, and supports multi-channel electrode selection and high-throughput data acquisition for electrochemical workstations.
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Figure CN117233223B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of chip detection, in particular to a multi-channel detection device and method. BACKGROUND
[0002] Electrochemical workstations are divided into single-channel workstations and multi-channel workstations; a single-channel workstation can only test one sample at a time, while a multi-channel workstation is equivalent to multiple single-channel workstations assembled together, and can test multiple samples at the same time, thus having higher testing efficiency; multi-channel workstations are suitable for scenarios that require large-scale research and development testing, and can significantly speed up research and development; however, the current market mainly uses single-channel workstations, and multi-channel workstation testing equipment is not integrated, has a large volume, information transmission is disturbed, different test interfaces need to be replaced to realize multi-channel testing, and the testing process and method are complicated, and the data collected by multi-channel detection needs to be transmitted to a computer for output. SUMMARY
[0003] This part aims to summarize some aspects of the embodiments of the present application and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this part and the abstract and title of the specification to avoid obscuring the purpose of this part, the abstract and the title, and such simplifications or omissions cannot be used to limit the scope of the present application.
[0004] In view of the above or the problem that different test interfaces need to be replaced to realize multi-channel testing in the prior art, the present application is proposed.
[0005] Therefore, the purpose of the present application is to provide a multi-channel detection circuit.
[0006] To solve the above technical problems, the present application provides the following technical solutions: a multi-channel detection circuit, comprising,
[0007] A data acquisition unit comprising a processing module, a channel selection module and a first power module, the processing module being connected to the channel selection module, and the first power module being connected to the processing module and the channel selection module respectively;
[0008] An interaction unit connected to the processing module and the first power module respectively.
[0009] As a preferred scheme of the multi-channel detection circuit of the present application, wherein: the channel selection module comprises a transimpedance preamplifier circuit and a constant potential circuit connected to the transimpedance preamplifier circuit;
[0010] The transimpedance preamplifier circuit and the constant potential circuit are connected to the first power module respectively.
[0011] As a preferred scheme of the multi-channel detection circuit, the resistance network circuit of the transimpedance preamplifier circuit is connected with the processing module.
[0012] As a preferred scheme of the multi-channel detection circuit, the transimpedance preamplifier circuit further comprises a reference electrode test port and a counter electrode test port.
[0013] The counter electrode test port is connected with the reference electrode test port.
[0014] As a preferred scheme of the multi-channel detection circuit, the interaction unit comprises a control module, a first USB interface and a second power module, and the control module is connected with the processing module and the first power module through the first USB interface.
[0015] The multi-channel detection circuit has the advantages that the single-channel connection multi-channel detection function can be realized through the cooperation between the processing module, the channel selection module, the first power module and the interaction unit, and the cumbersome multi-channel test through replacement of different test interfaces in the test process is avoided.
[0016] In actual use, the multi-channel workstation test equipment is not integrated, has a large size, and information transmission is disturbed.
[0017] To solve the above technical problems, the application further provides the following technical scheme: a multi-channel detection device comprises a multi-channel detection circuit, and a multi-channel detection device.
[0018] The bearing shell comprises a chip electrode slot and a mounting groove, and the control module is embedded in the mounting groove.
[0019] The chip electrode connection unit comprises a chip electrode connection circuit board and electrode springs and spring type wiring terminals connected on two sides of the chip electrode connection circuit board.
[0020] The reference electrode test port, the counter electrode test port and the working motor port of the constant potential circuit are connected with the spring type wiring terminals.
[0021] The electrode springs are embedded in the protective shell of the chip electrode connection unit, and the chip electrode connection circuit board and the spring type wiring terminals are arranged in the protective shell, and one end of the protective shell is embedded in the chip electrode slot and rotationally connected.
[0022] As a preferred scheme of the multi-channel detection device, the bearing shell is provided with a containing space.
[0023] The data acquisition unit is arranged in the accommodating space.
[0024] As a preferred scheme of the multi-channel detection device, the chip electrode card slot is arranged with a chip to be tested.
[0025] The electrode spring plate is connected with the chip to be tested.
[0026] The multi-channel detection device has the advantages that the data acquisition unit, the interaction unit, the bearing shell and the chip electrode connecting unit are integrated, the detection volume is greatly reduced, the information transmission anti-interference problem is reduced, and the detection speed and accuracy are improved.
[0027] In actual use, the test method is still needed, and the data collected by the multi-channel detection needs to be transmitted to a computer for output.
[0028] To solve the above technical problems, the application further provides the following technical scheme: a multi-channel detection method comprising a multi-channel detection device, the multi-channel detection method comprising the steps of,
[0029] The interaction unit is turned on, and the collection test mode is set.
[0030] The chip electrode connecting module is connected with the chip to be tested arranged in the chip electrode card slot.
[0031] The chip to be tested is subjected to four-stage life cycle test to obtain collected test data.
[0032] The collected test data is transmitted to the control module to calculate the peak height and draw a peak height cycle number graph.
[0033] As a preferred scheme of the multi-channel detection method, the four-stage life cycle comprises a collection interface life cycle, a sensor interface life cycle, a curve interface life cycle and a historical number life cycle.
[0034] The multi-channel detection method has the advantages that the circuit and software operation are combined to realize the multi-channel control of the electrochemical workstation cycle voltammetry (CV) and square wave voltammetry (SWV) of the chip electrode, and the square wave voltammetry (SWV) data is imported into the processing module for processing to realize the high-throughput collection and data processing function of the multi-channel chip electrode. BRIEF DESCRIPTION OF DRAWINGS
[0035] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without any creative effort on the basis of these drawings. Among them:
[0036] Figure 1 It is a schematic diagram of the overall multi-channel detection circuit.
[0037] Figure 2 It is a schematic diagram of the processing module of the multi-channel detection circuit.
[0038] Figure 3 It is a schematic diagram of the channel selection module of the multi-channel detection circuit.
[0039] Figure 4 It is a schematic diagram of the power supply display circuit of the multi-channel detection circuit.
[0040] Figure 5 It is a schematic diagram of the battery charging and discharging circuit of the multi-channel detection circuit.
[0041] Figure 6 It is a schematic diagram of the power monitoring circuit of the multi-channel detection circuit.
[0042] Figure 7 It is a schematic diagram of the voltage conversion circuit of the multi-channel detection circuit.
[0043] Figure 8 It is a schematic diagram of the serial port to UAB circuit of the multi-channel detection circuit.
[0044] Figure 9 It is a schematic diagram of the buzzer circuit of the multi-channel detection circuit.
[0045] Figure 10 It is a schematic diagram of the acquisition connection display circuit of the multi-channel detection circuit.
[0046] Figure 11 It is a schematic diagram of the overall multi-channel detection device.
[0047] Figure 12 It is a schematic diagram of the chip electrode connection unit of the multi-channel detection device.
[0048] Figure 13 It is a schematic diagram of the detection step flow of the multi-channel detection method.
[0049] Figure 14 It is a schematic diagram of the APP interface of the multi-channel detection method.
[0050] Figure 15 It is a schematic diagram of the menu bar-device interface of the multi-channel detection method.
[0051] Figure 16 Fig. 6 is a schematic diagram of a software page - menu bar - cyclic voltammetry mode setting interface for a multi-channel detection method.
[0052] Figure 17 Fig. 7 is a schematic diagram of a software page - menu bar - square wave voltammetry mode setting interface for a multi-channel detection method.
[0053] Figure 18 Fig. 8 is a schematic diagram of a software page - menu bar - import interface for a multi-channel detection method. DETAILED DESCRIPTION
[0054] In order to make the above objectives, features and advantages of the present application more apparent, specific embodiments of the present application will be described in detail below with reference to the accompanying drawings.
[0055] In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. However, it will be apparent to one skilled in the art that the present application can be practiced without the specific details given herein, that the present application can be practiced with other than the described implementations, and that the present application can be practiced with or in conjunction with other systems, materials or items than those described herein. In other instances, well-known structures and functions have not been described in detail in order to avoid obscuring the present application.
[0056] Secondly, the "one embodiment" or "embodiment" referred to herein can include specific features, structures or characteristics in at least one implementation of the present application. "In one embodiment" appearing in different places in the specification does not mean the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments.
[0057] Example 1
[0058] Reference Figure 1 and 2For the first embodiment of the application, the embodiment provides a multi-channel detection circuit, which comprises a data acquisition unit 100, which realizes accurate acquisition and bottom calculation of working electrode (WE) / reference electrode (CE) / counter electrode (RE), and is used for transmitting acquisition data to an interaction unit 200, wherein the data acquisition unit 100 comprises a processing module 101, a channel selection module 102 and a first power module 103, the processing module 101 can receive an instruction signal sent by the interaction unit 200, execute the detection of the channel selection module 102, and transmit the acquired chip data to be tested to the interaction unit 200, the channel selection module 102 provides multiple circuit channels of working electrode (WE), reference electrode (CE) and counter electrode (RE), realizes the multi-channel gating function of working electrode (WE), reference electrode (CE) and counter electrode (RE), the processing module 101 is connected with the channel selection module 102, corresponding circuit conduction is provided for different types of chips, and selection acquisition or sequential rotation acquisition of multi-channel electrodes is realized; the first power module 103 supplies power for the processing module 101 and the channel selection module 102, the first power module 103 is connected with the processing module 101 and the channel selection module 102 in one-way power transmission respectively; the interaction unit 200 plays a role of starting a detection program, sending an instruction signal, receiving acquisition data and proofreading, and is connected with the processing module 101 and the first power module 103 respectively, specifically, the processing module 101 is of STM32H750 type.
[0059] Further, as Figure 3 , the channel selection module 102 comprises a transimpedance preamplifier circuit 102a and a constant potential circuit 102b connected with the transimpedance preamplifier circuit 102a, the transimpedance preamplifier circuit 102a provides reference electrode (CE) and counter electrode (RE) circuit channels, the constant potential circuit 102b provides working electrode (WE) circuit channel, and the cooperation between the transimpedance preamplifier circuit 102a and the constant potential circuit 102b provides the basis for selection acquisition or sequential rotation acquisition of multi-channel electrodes of the chip to be tested.
[0060] The resistance network circuit 102a-1 of the transimpedance preamplifier circuit 102a is connected with the processing module 101, and can realize the two-way information signal transmission of starting the data collection of the reference electrode (CE) and the counter electrode (RE) circuit channel and the data collection and data transmission of the chip. Specifically, the pin 8 (D), the pin 1 (A0), the pin 16 (A1) and the pin 15 (A2) of the single-chip microcomputer U9 of the transimpedance preamplifier circuit 102a are respectively connected with the pin 55 (RE), the pin 24 (PA3), the pin 20 (PA1) and the pin 22 (PA2) of the processing module 101 in correspondence, and the pin 8 (D), the pin 1 (A0), the pin 16 (A1) and the pin 15 (A2) of the single-chip microcomputer U10 of the resistance network circuit 102a-1 are respectively connected with the pin 54 (CE), the pin 24 (PA3), the pin 20 (PA1) and the pin 22 (PA2) of the processing module 101 in correspondence.
[0061] The constant potential circuit 102b is used for receiving the starting collection signal of the transimpedance preamplifier circuit 102a, and unidirectionally transmitting the chip data collected by the working electrode (WE) circuit channel to the processing module 101 and the transimpedance preamplifier circuit 102a. The constant potential circuit 102b is unidirectionally connected with the processing module 101. Specifically, the pin 8 (D), the pin 1 (A0), the pin 16 (A1) and the pin 15 (A2) of the single-chip microcomputer U7 of the constant potential circuit 102b are respectively connected with the pin 53 (WE), the pin 24 (PA3), the pin 20 (PA1) and the pin 22 (PA2) of the processing module 101 in correspondence. It should be noted that the models of the single-chip microcomputers U9, U10 and U7 are ADG1408YRUZ.
[0062] It should be noted that the transimpedance preamplifier circuit 102a further comprises a reference electrode test port 102a-2 and a counter electrode test port 102a-3; wherein the counter electrode test port 102a-3 is unidirectionally connected to the reference electrode test port 102a-2 to transmit counter electrode collection data; the constant potential circuit 102b comprises a working electrode test port 102b-1, the reference electrode test port 102a-2 and the counter electrode test port 102a-3 are integratedly connected on the chip electrode connection circuit board through wires; it should be noted that the working electrode test port 102b-1, the reference electrode test port 102a-2 and the counter electrode test port 102a-3 are respectively provided with 8 circuit channels (not limited to 8, according to detection) of pin 4 (S1), pin 5 (S2), pin 6 (S3), pin 7 (S4), pin 12 (S5), pin 11 (S6), pin 10 (S7) and pin 9 (S8), the 8 ports of the working electrode test port 102b-1, the reference electrode test port 102a-2 and the counter electrode test port 102a-3 are respectively connected to 8 chip electrode connection circuit boards, which are divided into 8 three-electrode channels through three ADG1408YRUZ digital-to-analog converters, so that the chip electrode connection module can be designed and replaced for different microfluidic chips (i.e. to be tested), and 8 channels of the 8 electrodes can be detected at the same time, thereby accelerating the detection and collection efficiency.
[0063] Further, the transimpedance preamplifier circuit 102a and the constant potential circuit 102b are respectively connected with the first power module 103; specifically, the first power module 103 comprises a power supply display circuit 103a, a battery charging and discharging circuit 103b, a power monitoring circuit 103c and a voltage conversion circuit 103d; specifically, as shown in Figure 4 , the power supply display circuit 103a is used to display whether the external 12V power is normally connected (if connected, the green light is on; if not connected, the green light is not on); as shown in Figure 5 , the battery charging and discharging circuit 103b can charge and store and supply power to the voltage conversion circuit 103d, B1 and B6 in the figure are series and parallel connection of batteries, Q1 to Q3 are MOSFET circuits for balancing battery charging and discharging to balance the charging between the batteries; as shown in Figure 6 , the power monitoring circuit 103c is a voltage dividing circuit for collecting voltage for ADC and judging battery power, the pin ADC-CH1 of the power monitoring circuit 103c is connected with the pin 18 (PA0) of the processing module 101; as shown in Figure 7As shown, the voltage conversion circuit 103d plays a role to stabilize and convert voltage, thereby providing isolated stabilized DC ±6V operational amplifier analog power supply, +3.3V analog and digital power supply, +5V and +5.5V digital power supply required for detection and collection by the processing module 101 and the channel selection module 102, wherein the A+6V voltage input by the voltage conversion circuit 103d is connected in parallel with the pin 7 (A+6V) and the pin 9 (A+6V) of the processing module 101, and the MCU pin 2 (EN) and the pin 13 (VDD) of the transimpedance preamplifier circuit 102a, the constant potential circuit 102b and the resistance network circuit 102a-1, respectively, the A+6V voltage input by the voltage conversion circuit 103d is connected in parallel with the pin 8 (A-6V), the pin 10 (A-6V) of the processing module 101, and the MCU pin 3 (VSS) of the transimpedance preamplifier circuit 102a, the constant potential circuit 102b and the resistance network circuit 102a-1, respectively, and the D+3.3V voltage input by the voltage conversion circuit 103d is connected with the pin 39 (D+3.3V) and the pin 41 (D+3.3V) of the processing module 101, etc.; it should be noted that the 12V external power supply is connected with the power display circuit 103a, the battery charging and discharging circuit 103b, the power monitoring circuit 103c and the voltage conversion circuit 103d, respectively.
[0064] Further, the interaction unit 200 comprises a control module 201, a first USB interface 202 and a second power module 203, the control module 201 is connected with the processing module 101 and the first power module 103 through the first USB interface 202, the second power module 203 is connected with an external circuit template, wherein the control module 201 plays a role in sending multi-channel acquisition signals, receiving acquisition data and calibrating and comparing the acquisition data, and can be a touch display panel (performance: Cortex A9, 1GB DDR3, 8GB eMMC, Android 5.1), which has specific man-machine interface software, supports sampling parameter editing, supports dynamic graphic display in the sampling process, supports real-time storage of data in the sampling process, and supports sampling data table display and other functions, while the second power module 203 comprises a 220C AC-to-12V DC power adapter, a 12V DC lithium battery (capacity 5000ma / h) and a 12V DC circuit, the 220C AC-to-12V DC power adapter is connected with the 12V DC circuit through the 12V DC lithium battery (capacity 5000ma / h); wherein the first USB interface 202 is connected with the serial port of the processing module 101 through the conversion module 104 of the data acquisition unit 100, and the transmission interface 202; specifically, the second USB interface 104a of the conversion module 104 is connected with the first USB interface 202, the serial port-to-UAB circuit 104b and the first power module 103, respectively, the serial port-to-UAB circuit 104b transmits acquisition data for the processing module 101 and detects the acquisition communication interface for the control module 201, wherein, as shown in Figure 8 the pin NC and the pin CH-RXD of the serial port-to-UAB circuit 104b are connected with the pin 36 (PA9) of the processing module 101, and the pin CH-TXD and the pin NC of the serial port-to-UAB circuit 104b are connected with the pin 38 (PA10).
[0065] Further, the data acquisition unit 100 further comprises an alarm template 105, the alarm template 105 comprises a buzzer circuit 105a and an acquisition connection display circuit 105b, the buzzer circuit 105a plays a role in prompting sound after acquisition is completed, as shown in Figure 9 the pin of the buzzer circuit 105a is connected with the pin 48 (PA15) of the processing module 101, and the acquisition connection display circuit 105b is provided with green, yellow and blue prompt lights, when the chip to be detected is connected with the working electrode test port 102b-1, the reference electrode test port 102a-2 and the counter electrode test port 102a-3, the green, yellow and blue prompt lights will be lit respectively, indicating that the multi-channel has been normally connected, specifically, as shown in Figure 10As shown, the pin LED-SYS, the pin LED-CH1 and the pin LED-CH2 connected with the display circuit 105b are respectively connected with the pin 45 (PC13), the pin 47 (PC14) and the pin 49 (PC15) of the processing module 101.
[0066] Further, the main hardware parameter range of the data acquisition unit 100 is provided herein:
[0067] Voltage range: ±10V;
[0068] Tank voltage: ±10V (Max);
[0069] Current range: ±100mA / ±200mA / ±400mA;
[0070] Reference electrode input impedance: 1MΩ;
[0071] Sensitivity range: 4×10-8-0.1 / 0.2 / 0.4A, total eight grades;
[0072] Input bias current: <10 pA;
[0073] Current measurement resolution: <1 pA;
[0074] Data acquisition system: 16-bit sampling, maximum 100KHz;
[0075] Power supply: DC12V / 1.5A.
[0076] The present application can realize the function of single-channel (single electrode) connection multi-channel detection by the mutual cooperation between the processing module, the channel selection module, the first power module and the interaction unit, and avoids the cumbersome that different test interfaces need to be replaced in the test process to realize multi-channel test.
[0077] Example 2
[0078] Reference Figure 11~Figure 12For the second embodiment of the application, unlike the previous embodiment, this embodiment provides a multi-channel detection device, which solves the problems of non-integration, large size and information transmission disturbance of the multi-channel workstation test equipment, and comprises a multi-channel detection circuit; and a bearing shell 300 comprising a chip electrode slot 301 and a mounting groove 302, the chip electrode slot 301 provides a containing space for the chip to be tested, and the mounting groove 302 is used for embedding and mounting the control module 201 on the multi-channel detection device, thereby realizing the integration of the detection equipment, and the control module 201 is embedded in the mounting groove 302; a chip electrode connection unit 400 comprising a chip electrode connection circuit board 401 and spring-type wiring terminals 403 and electrode spring sheets 402 provided on both sides of the chip electrode connection circuit board 401 respectively; wherein the reference electrode test port 102a-2, the counter electrode test port 102a-3 and the working motor port 102b-1 of the constant potential circuit 102b are all provided with wires welded with the spring-type wiring terminals 403, thereby realizing the detection of the multi-channel electrochemical chip (i.e. the chip to be tested), and the detection data can be directly processed by the equipment. At the same time, the device can also be equipped with corresponding circuit conduction modules for different types of chip electrodes, realizing the selection collection or sequential rotation collection of multi-channel electrodes.
[0079] Specifically, the electrode spring sheet 402 is used for circuit connection with the electrode of the chip to be tested, the electrode spring sheet 402 is embedded in the protective shell 404 of the chip electrode connection unit 400, the chip electrode connection circuit board 401 and the spring-type wiring terminal 403 are arranged in the protective shell 404, and the shafts on both sides of one end of the protective shell 404 are embedded in the chip electrode slot 301 through rotating connection. During detection and collection, the protective shell 404 is rotated, and the electrode spring sheet 402 will be embedded in the measurement hole of the chip to be tested.
[0080] It should be noted that the bearing shell 300 is provided with a containing space, wherein the data acquisition unit 100, the first USB interface 202 and the second power module 203 are arranged in the containing space, the containing space of the bearing shell 300 plays a role of bearing and protecting the data acquisition unit 100, the first USB interface 202 and the second power module 203, and provides a basis for integrated detection.
[0081] Further, the chip electrode slot 301 is provided with a chip to be tested; wherein the electrode spring sheet 402 is connected with the chip to be tested, specifically, the chip electrode slot 301 is provided with one slot, and the chip to be tested is clamped in the slot, the chip to be tested is an eight-channel chip containing eight electrodes, and the spring sheet of the electrode spring sheet 402 is in contact with the measurement pin of the chip to be tested.
[0082] The chip electrode connection unit 400 can be modified according to different types of electrodes. It can connect to chip electrodes, or the electrode connection module can be replaced with ordinary electrode clips for connecting ordinary electrodes (non-chip electrodes). The connection method does not affect the use of the program.
[0083] This invention integrates the data acquisition unit, interaction unit, carrier housing, and chip electrode connection unit into one unit, which greatly reduces the detection volume, reduces the anti-interference problem of information transmission, and improves the detection speed and accuracy.
[0084] Example 3
[0085] Reference Figure 13 This is the third embodiment of the present invention. Unlike the previous embodiment, this embodiment provides a multi-channel detection method, including a multi-channel detection device. The steps of the multi-channel detection method include: activating the interaction unit 200 and setting the acquisition test mode; connecting the chip electrode connection unit 400 to the chip under test placed in the chip electrode slot 301; performing a four-stage life cycle test on the chip under test and acquiring the acquired test data; transmitting the acquired test data to the control module 201 to calculate the peak height and plotting it as a peak height-cycle count graph.
[0086] Furthermore, the steps to enable the interactive unit 200 and set the data collection and testing method include:
[0087] Turn on the control module 201 switch of the interaction unit 200;
[0088] Start the multi-channel detection APP of the control module 201;
[0089] Main program starts;
[0090] Main program creation;
[0091] Link the interface to the record page;
[0092] Initialize USB authorization status to unknown;
[0093] Initialize the broadcast receiver to listen for USB insertion;
[0094] Bind a status control.
[0095] It should be noted that, as Figure 14 As shown, the multi-channel detection APP software mainly includes a menu bar, a real-time data selection box, and a status bar; the menu bar includes: Device, Mode, Start, Stop, Calibration, Export, Import, and About; specifically, as... Figure 15 As shown, the device menu bar indicates whether the device is properly connected to the electrochemical workstation, i.e., the data acquisition unit 100; the mode menu bar offers two electrochemical detection method options, meaning two modes are available, such as... Figure 16 and17 As shown, the cyclic voltammetry (CV) and square wave voltammetry (SWV) can set the relevant detection parameters in the cyclic voltammetry selection page, including the range (Range), the initial voltage (Init E), the highest voltage (High E), the lowest voltage (Low E), the scan rate (ScanRate), the quiet time (Quiet Time), the sample interval (Sample Int), the sweep segment (SweepSegment) and the electrode channel selection (Channel Switch); the square wave voltammetry selection page can set the relevant detection parameters, including the range (Range), the initial voltage (Init E), the final voltage (Final E), the incremental voltage (Incr E), the amplitude (Amplitude), the frequency (Frequency), the quiet time (Quiet Time), the cycle times (Sycle Times), the cycle interval (Cycle Interval), the start channel selection (Start Channel) and the end channel selection (End Channel); the start menu bar is used to control the detection start; the stop menu bar is used to control the detection stop; the calibration menu bar is used for the detection state calibration; the export menu bar is used for the current detection result data export; the import menu bar is used for importing the square wave voltammetry data, and after importing, the peak height can be calculated and drawn into the peak height-cycle times graph according to the square wave voltammetry real-time detection of each channel, such as Figure 18 As shown; the import menu bar records the basic performance of the software; the interface also sets a real-time data selection box, which displays the data being detected when checked, and displays the result graph of the imported data when unchecked; the software interface also sets a status bar, including the stop state display (Stop), the overflow display (Overflow) and the state of charge (SOC).
[0096] Further, the chip electrode connecting unit 400 is embedded and inserted into the to-be-tested chip placed in the chip electrode slot 301 through the electrode spring sheet 402 of the chip electrode connecting unit 400.
[0097] Further, the four-stage life cycle test is performed on the to-be-tested chip, and the steps of acquiring and collecting the test data include:
[0098] Start the automatic refresh status bar timing task;
[0099] Main program passage state;
[0100] Main program recovery initialization;
[0101] Register the broadcast receiver;
[0102] Detect whether the to-be-tested chip is connected;
[0103] Connect the chip to be tested;
[0104] After connection, start running the main program;
[0105] Four-stage life cycle test is performed on the chip to be tested;
[0106] The buzzer circuit 105 emits an alarm sound, and the broadcast receiver is logged out;
[0107] Acquire the test data collected.
[0108] It should be noted that the detection of whether the chip to be tested is connected is performed by collecting the connection display circuit 105b provided with green, yellow and blue indicator lights. When the chip to be tested is connected to the working electrode test port 102b-1, the reference electrode test port 102a-2 and the counter electrode test port 102a-3, the green, yellow and blue indicator lights will be lit respectively, indicating that the multi-channel has been normally connected. If the green, yellow and blue lights are not lit or not all lit, check the USB unknown or authorized state. If yes, connect the chip to be tested; if no, start running the main program.
[0109] It should be noted that the four-stage life cycle includes the acquisition interface life cycle, the sensor interface life cycle, the curve interface life cycle and the historical quantity life cycle. The acquisition interface life cycle, the sensor interface life cycle, the curve interface life cycle and the historical quantity life cycle test adopt an automatic mutual switching mode of program, which can be realized by editing program code.
[0110] It should be noted that after the broadcast receiver is logged out, the test process can be ended, or the four-stage life cycle test can be performed on the chip to be tested again.
[0111] Further, the step of transmitting the test data collected to the control module 201 to calculate the peak height and draw a peak height-cycle number graph includes:
[0112] Stop the test program and disconnect the chip to be tested;
[0113] The test data collected is transmitted to the APP data display interface of the control module 201 through the switching module 104 and the first USB interface 202;
[0114] Import square wave voltammetry data;
[0115] According to the real-time detection of square wave voltammetry of each channel, the peak height is calculated and a peak height-cycle number graph is drawn.
[0116] The square wave voltammetry (SWV) graph of real-time detection can directly output the detection result by importing data, realizing the function of detecting the chip electrode from the test to the output of the result.
[0117] The steps of selecting collection or sequentially rotating collection for the tested chip: setting the relevant detection parameters in the square wave voltammetry selection page of the mode menu bar, wherein the range, the initial voltage, the final voltage, the quiet time and the meaning and setting range in the cyclic voltammetry parameter setting are the same, in addition, the incremental voltage (Incr E): the step value of the potential during the process from the initial potential to the terminal potential, the required voltage value can be input by the keyboard, the setting range is "1-1000 mV"; the amplitude (Amplitude): the difference between the adjacent two stable potentials, the parameter setting range is "1-1000 mV"; the frequency (Frequency) pulse frequency, the parameter setting range is "1-500"; the cycle times (SycleTimes): the square wave voltammetry scanning times of each electrode channel from the initial potential to the terminal potential, the scanning is calculated as one cycle from the start electrode channel to the end electrode channel; the cycle interval time (Cycle Interval): the time interval setting from the start electrode channel to the next electrode channel, the unit is second; the cycle start electrode channel selection (Start Channel): the first electrode channel of the square wave voltammetry cycle scanning; the cycle end electrode channel selection (End Channel): the last electrode channel of the square wave voltammetry cycle scanning. If the cycle start electrode channel selection and the cycle end electrode channel selection are set to the same electrode channel, then the program will cycle the scanning of the electrode channel according to the cycle interval time.
[0118] When the cyclic voltammetry interface is selected in the mode menu bar, "select collection" means selecting the specified channel for collection in the "Channel Switch" bar. After selection, the touch screen instruction is transmitted to the ARM processor through the USB interface, so that the ARM processor controls the ADG1408YRUZ digital-analog converter to select one channel of the eight channels.
[0119] After selecting the square wave voltammetry interface, the principle of "select collection" is the same as that of cyclic voltammetry, and "sequentially rotating collection" is through setting the cycle times, the cycle interval time, the cycle start electrode channel selection, the cycle end electrode channel selection, then the touch screen instruction is transmitted to the ARM processor through the USB interface, and the ARM processor controls the ADG1408YRUZ digital-analog converter to sequentially rotate the selected channels according to the instruction according to the time interval.
[0120] The application realizes the cyclic voltammetry (CV) and square wave voltammetry (SWV) of the electrochemical workstation with multi-channel chip electrode control by combining the circuit with the software operation, and realizes the high-throughput collection and data processing function of the multi-channel chip electrode by processing the imported square wave voltammetry (SWV) data by using the processing module 101. Secondly, a new detection method is provided for the high-throughput chip data collection method through the chip electrode connection module design.
[0121] Importantly, it should be noted that the constructions and arrangements of the present application shown in the various exemplary embodiments are illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review this disclosure will readily appreciate that many modifications can be made to the embodiments without materially departing from the novel teachings and advantages of the subject matter described in this application (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc.). For example, an element shown as integrally formed can be constructed of multiple parts or elements, the position of an element can be reversed or otherwise varied, and the nature or number of sub-elements or positions can be altered or varied. Accordingly, all such modifications are intended to be included within the scope of the present application. The order or sequence of any process or method steps can be varied or re-sequenced without departing from the subject matter. Any "device" or "structure" as used herein is intended to encompass a structure which is equivalent in function to the recited structure, and is not limited to the structure itself. Other substitutions, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present application. Accordingly, the present application is not limited to the particular embodiments described, but extends to various modifications that still fall within the scope of the appended claims.
[0122] Furthermore, in the interest of providing a concise description of exemplary embodiments, not all features of an actual implementation can be described (i.e., those unrelated to the best mode of practicing the present application, or those unrelated to enabling the present application).
[0123] It should be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions can be made. Such development efforts might be complex and time-consuming, but would nevertheless be a routine undertaking of design, fabrication, and manufacture for those of ordinary skill having the benefit of this disclosure.
[0124] It should be noted that the above examples are only used to illustrate the technical solutions of the present application but not limit the present application. Although the present application is described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or equivalently replaced, without departing from the spirit and scope of the technical solutions of the present application, which should be covered in the scope of the claims of the present application.
Claims
1. A multi-channel detection device, characterized by: The application relates to a data acquisition device, which comprises a data acquisition unit (100), an interactive unit (200) and a bearing shell (300). The data acquisition unit (100) comprises a processing module (101), a channel selection module (102) and a first power module (103), the processing module (101) is connected with the channel selection module (102), and the first power module (103) is connected with the processing module (101) and the channel selection module (102) respectively. The interactive unit (200) is connected with the processing module (101) and the first power module (103) respectively, and comprises a control module (201), a first USB interface (202) and a second power module (203). The control module (201) is connected with the processing module (101) and the first power module (103) through the first USB interface (202). The bearing shell (300) comprises a chip electrode slot (301) and a mounting groove (302), and the control module (201) is embedded in the mounting groove (302). The chip electrode connection unit (400) comprises a chip electrode connection circuit board (401) and electrode spring sheets (402) and spring type wiring terminals (403) connected on two sides of the chip electrode connection circuit board (401) respectively. The channel selection module (102) comprises a transimpedance preamplifier circuit (102a) and a constant potential circuit (102b) connected with the transimpedance preamplifier circuit (102a). The transimpedance preamplifier circuit (102a) and the constant potential circuit (102b) are connected with the first power module (103) respectively. The resistance network circuit (102a-1) of the transimpedance preamplifier circuit (102a) is connected with the processing module (101). The transimpedance preamplifier circuit (102a) further comprises a reference electrode test port (102a-2) and a counter electrode test port (102a-3). The counter electrode test port (102a-3) is connected with the reference electrode test port (102a-2). The reference electrode test port (102a-2), the counter electrode test port (102a-3) and the working motor port (102b-1) of the constant potential circuit (102b) are connected with the spring type wiring terminals (403).
2. The multi-channel detection device of claim 1, wherein: The electrode spring sheets (402) are embedded in a protective shell (404) of the chip electrode connection unit (400), the chip electrode connection circuit board (401) and the spring type wiring terminals (403) are arranged in the protective shell (404), and one end of the protective shell (404) is rotatably connected with the chip electrode slot (301). The bearing shell (300) is provided with a containing space.
3. The multi-channel detection device of claim 2, wherein: The data acquisition unit (100) is arranged in the containing space. The chip electrode slot (301) is provided with a to-be-tested chip.
4. A detection method using the multi-channel detection device according to any one of claims 1 to 3, characterized by: The electrode spring sheets (402) are connected with the to-be-tested chip. The application further discloses a data acquisition method. The opening interaction unit (200) sets the collection test mode; The chip electrode connection unit (400) is connected with the to-be-tested chip placed in the chip electrode slot (301); The four-stage life cycle test is performed on the to-be-tested chip to obtain the collection test data; The collection test data is transmitted to the control module (201) to calculate the peak height and draw a peak height-cycle number graph.
5. The method of claim 4, wherein: The four-stage life cycle includes a collection interface life cycle, a sensor interface life cycle, a curve interface life cycle, and a history quantity life cycle.
Citation Information
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