Use of a stabilizer in improving high-temperature emulsion stability of a cosmetic
By using a combination of betaine and 1,2-pentanediol as a stabilizer in cosmetics, the problem of decreased emulsification efficiency of polyoxyethylene nonionic emulsifiers at high temperatures was solved, thereby improving the high-temperature stability and moisturizing properties of cosmetics.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- YUNNAN BOTANEE BIO TECH GRP CO LTD
- Filing Date
- 2023-10-23
- Publication Date
- 2026-06-05
Smart Images
Figure CN117323248B_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of cosmetic technology and relates to the application of a stabilizer in improving the high-temperature emulsification stability of cosmetics. Background Technology
[0002] Modern research shows that betaine primarily possesses the ability to rapidly improve skin and hair moisture retention, exhibiting unique moisturizing and cell membrane protection properties. It also increases the solubility of active ingredients in water and reduces the skin irritation caused by surfactants or fruit acids. When used in personal care products, betaine acts as an organic penetrant, penetrating the stratum corneum to protect the osmotic balance of cells, thereby increasing the moisture content of the skin's surface. Betaine's unique moisturizing mechanism distinguishes its moisturizing performance from commonly used moisturizers; compared to sodium hyaluronate, betaine can maintain a long-lasting moisturizing effect even at very low concentrations. Furthermore, adding betaine can significantly reduce the skin irritation caused by surfactants such as SLS. Adding betaine to toothpaste and mouthwash products can significantly reduce the irritation of SLS to the oral mucosa.
[0003] Emulsifiers, as an important component of cosmetic raw materials, play a role in emulsification, dispersion, solubilization, lubrication, softening, and stabilization. Commonly used emulsifiers include nonionic emulsifiers, ionic emulsifiers, and amphoteric emulsifiers. Among them, anionic emulsifiers have poor resistance to hard water, cannot be used in the same emulsion system as cationic emulsifiers, and have higher irritation, so they are increasingly less chosen by formulators. Nonionic emulsifiers, on the other hand, have a wide range of selectivity, strong emulsifying performance, and high mildness, making them the most widely used type of emulsifier. Polyoxyethylene nonionic emulsifiers are one such example.
[0004] In today's era of functional skincare products, formulations often contain a variety of high-content active ingredients, which are typically added at the final low-temperature stage. This reduces the amount of pure water in the formulation. If polyoxyethylene nonionic emulsifiers are used in these formulations, the system may experience a decrease in emulsification efficiency under high-temperature conditions when following conventional production processes. Because some polyoxyethylene nonionic emulsifiers have hydrophilic and lipophilic groups of similar size, and their hydrophilicity and lipophilicity are relatively sensitive to temperature, when the temperature rises, the hydration degree of the hydrophilic group weakens. When emulsifying in the presence of some polymers with strong hydration ability, the hydrophilic competitiveness of these emulsifiers is relatively weak, and the emulsification efficiency decreases, making it impossible to form an O / W structure. Although the hydrophilicity of the emulsifier increases as the temperature decreases, and it tends to form an O / W structure again, it is difficult to form a stable O / W emulsion system through phase inversion emulsification. This is because it is difficult to emulsify complex oil phases with high carbon number and high viscosity. Moreover, in order to stabilize the system, the amount of emulsifier used in phase inversion emulsification is significantly higher than that used in conventional emulsification methods. The increase in the amount of emulsifier used will also affect the safety of the formulation. For example, patent CN107281005A discloses an anti-wrinkle composition and its PIT nanoemulsion preparation, in which the amount of emulsifier is as high as 12.8%. In contrast, conventional emulsification methods require lower amounts of emulsifiers and are relatively easier to emulsify various oil phases. To address the issue of decreased high-temperature emulsification efficiency of polyoxyethylene nonionic emulsifiers in conventional production processes, it is generally necessary to introduce emulsifiers with high HLB values to assist emulsification. However, this may lead to formulation irritation issues due to high emulsifier content, affecting the mildness of the formulation. Another approach is to reduce the amount of polymeric thickener used in the high-temperature emulsification stage, adding the remaining polymeric thickener at low temperatures after emulsification. However, this is not only cumbersome in terms of operation but also carries the risk of difficulty in dispersing the thickener powder and incomplete swelling. Summary of the Invention
[0005] In view of the shortcomings of the prior art, the purpose of this invention is to provide an application of a stabilizer in improving the high-temperature emulsification stability of cosmetics.
[0006] To achieve this objective, the present invention employs the following technical solution:
[0007] In a first aspect, the present invention provides the application of a stabilizer in improving the high-temperature emulsification stability of cosmetics, said stabilizer comprising betaine and 1,2-pentanediol.
[0008] The combination of betaine and 1,2-pentanediol is used as a stabilizer. Water is used as a solvent. The mixture is added to the system during emulsification at high temperature (80-85°C) to help improve the high-temperature emulsification stability of the formulation. This method is simple and risk-free.
[0009] Preferably, the mass ratio of betaine to 1,2-pentanediol in the stabilizer is (1-5):(1-5), wherein the specific point values in (1-5) are 1, 1.2, 1.5, 1.8, 2, 2.2, 2.5, 2.8, 3, 3.2, 3.5, 3.8, 4, 4.2, 4.5, 4.8, 5, etc. Other specific point values within the above range can be selected, and will not be elaborated here.
[0010] Preferably, the stabilizer in the cosmetic is in the range of 2-10 parts by weight, such as 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 parts, etc. Other specific values within the above range can be selected, and will not be elaborated here.
[0011] Preferably, the stabilizer is added to the system using water as a solvent during high-temperature emulsification.
[0012] Preferably, the cosmetic is a cosmetic that uses polyoxyethylene nonionic emulsifiers.
[0013] The polyoxyethylene nonionic emulsifiers include stearyl alcohol polyether-21 / stearyl alcohol polyether-2, cetearyl alcohol polyether-12 / glyceryl stearate, or polyoxyethylene sorbitan monooleate / sorbitan monooleate.
[0014] In a second aspect, the present invention provides an emulsion comprising an emulsifier, a moisturizer, a thickener, a stabilizer, a skin-moisturizing oil, an antioxidant, a skin conditioning agent, and water.
[0015] Preferably, the emulsion comprises, by weight, 2-5 parts emulsifier, 5-15 parts moisturizer, 0.1-0.5 parts thickener, 2-10 parts stabilizer, 10-25 parts moisturizing oil, 0.01-0.5 parts antioxidant, 15-25 parts skin conditioning agent, and water.
[0016] Preferably, the stabilizer comprises betaine and 1,2-pentanediol.
[0017] Preferably, the mass ratio of betaine to 1,2-pentanediol is (1-5):(1-5).
[0018] The emulsifier can be selected in parts by weight of 2, 2.5, 3, 3.5, 4, 4.5, 5, etc.; the humectant can be selected in parts by weight of 5, 5.5, 6, 6.5, 7, 7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 11.5, 12, 12.5, 13, 13.5, 14, 14.5, 15, etc.; the thickener can be selected in parts by weight of 0.1, 0.2, 0.3, 0.4, 0.5, etc.; and the stabilizer can be selected in parts by weight of 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5, 8, etc. The mass fractions of the moisturizing oil can be selected from 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, etc. The mass fractions of the antioxidant can be selected from 0.01, 0.02, 0.05, 0.08, 0.1, 0.2, 0.3, 0.4, 0.5, etc. The mass fractions of the skin conditioning agent can be selected from 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, etc. Other specific values within the above ranges can be selected, and will not be elaborated here.
[0019] Preferably, the moisturizer includes any one or a combination of at least two of glycerin, propylene glycol, butylene glycol, hexanediol, or sodium hyaluronate.
[0020] Preferably, the thickener comprises any one or a combination of at least two of the following: sodium acrylate copolymer / lecithin, ammonium acryloyldimethyl taurate / VP copolymer, sodium polyacryloyldimethyl taurate, sodium polyacrylate, or hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer.
[0021] Preferably, the moisturizing oil comprises any one or a combination of at least two of the following: shea butter, squalane, tridecyl trimellitate, petrolatum, caprylic / capric triglyceride, hydrogenated polyisobutylene, beeswax, sclerotinia oil, tocopheryl acetate, sunflower seed oil unsaponifiables, cetearyl alcohol, behenyl alcohol, or polydimethylsiloxane.
[0022] Preferably, the emulsifier comprises any one or a combination of at least two of stearyl alcohol polyether-21 / stearyl alcohol polyether-2, cetearyl alcohol polyether-12 / glyceryl stearate, or polyoxyethylene sorbitan monooleate / sorbitan monooleate.
[0023] Preferably, the skin conditioning agent comprises any one or a combination of at least two of the following: purslane extract, gardenia fruit extract, β-glucan, calendula flower extract, flaxseed extract, ophiopogon root extract, or frankincense resin extract.
[0024] Thirdly, the present invention provides a method for preparing an emulsion according to the second aspect, the method comprising:
[0025] (1) Mix water, humectant, and thickener to obtain an aqueous phase; mix skin-moisturizing oil with emulsifier to obtain an oil phase;
[0026] (2) Mix the aqueous phase material, stabilizer and oil phase material, homogenize them to obtain the first mixture;
[0027] (3) The first mixture is mixed with an antioxidant to obtain a second mixture;
[0028] (4) Mix the second mixture with the skin conditioning agent to obtain the final product.
[0029] Preferably, the mixing temperature in steps (1) and (2) is independently 80-85℃, such as 80℃, 81℃, 82℃, 83℃, 84℃, 85℃, etc. Other specific values within the above range can be selected, and will not be described in detail here.
[0030] Preferably, the stabilizer is prepared by mixing water, betaine and 1,2-pentanediol at 80-85°C.
[0031] Preferably, the mixing temperature in step (3) is 70-75℃, such as 70℃, 71℃, 72℃, 73℃, 74℃, 75℃, etc. Other specific values within the above range can be selected, and will not be described in detail here.
[0032] Preferably, the mixing temperature in step (4) is 40-45℃, such as 40℃, 41℃, 42℃, 43℃, 44℃, 45℃, etc. Other specific values within the above range can be selected, and will not be described in detail here.
[0033] Preferably, the homogenization time is 10-15 minutes, such as 10 minutes, 11 minutes, 12 minutes, 13 minutes, 14 minutes, 15 minutes, etc. Other specific values within the above range can be selected, and will not be elaborated here.
[0034] Compared with the prior art, the present invention has the following beneficial effects:
[0035] This invention addresses the issue of decreased emulsifying efficiency of some polyoxyethylene nonionic emulsifiers in functional cosmetic formulations under high-temperature conditions. It utilizes a combination of betaine and 1,2-pentanediol as a stabilizer, added to the system during high-temperature emulsification using water as a solvent. This helps improve the high-temperature emulsification stability of the formulation, resulting in an O / W formulation with excellent stability. Compared to the potentially cumbersome process and risks associated with adding polymeric thickeners at low temperatures, such as difficulty in powder dispersion and incomplete swelling, the process using the betaine and 1,2-pentanediol combination as a stabilizer is simpler and risk-free. Introducing additional emulsifiers to enhance stability may lead to formulation irritation issues due to high emulsifier content, while the addition of betaine further improves the moisturizing and mildness of the formulation. Attached Figure Description
[0036] Figure 1 The particle size (200X) of the material after high-temperature emulsification in Example 1.
[0037] Figure 2 The particle size (200X) of the material after high-temperature emulsification in Comparative Example 1 is shown.
[0038] Figure 3 This is the appearance of the material after high-temperature emulsification in Example 1.
[0039] Figure 4 This is the appearance of the material after high-temperature emulsification in Comparative Example 1.
[0040] Figure 5 The particle size (200X) of the finished formulation of Example 1 is shown.
[0041] Figure 6 The particle size (200X) of the finished formulation of Comparative Example 1 is shown. Detailed Implementation
[0042] The technical solution of the present invention will be further illustrated below through specific embodiments. Those skilled in the art should understand that the embodiments described are merely illustrative of the present invention and should not be construed as limiting the invention.
[0043] The sources of the active ingredients in the products involved in the following examples and comparative examples are as follows (only the active ingredients are shown; the necessary excipients contained in other commercially available raw materials are not described):
[0044] Sodium polyacrylamide dimethyl taurate was purchased from Clariant under the product name Aristoflex Silk.
[0045] The sodium hyaluronate was purchased from Freda Company under the product name "low molecular weight sodium hyaluronate";
[0046] Stearyl alcohol polyether-21 was derived from a product purchased from BASF under the trade name Eumulgin S21.
[0047] Stearyl alcohol polyether-2 was derived from a product purchased from BASF under the trade name Eumulgin S2.
[0048] Shea butter is derived from a product called LIPEX Sheasoft purchased from AAK Company;
[0049] The petroleum grease was purchased from Yazhilong Company under the product name Smallyn 190;
[0050] Hydrogenated polyisobutylene was sourced from a product called Leybold Corporation. H-300E products;
[0051] The polydimethylsiloxane was purchased from Dow Corning's product, which was marketed as PMX200-350cst.
[0052] The beeswax was purchased from Zibang Company under the product name BINSOLI BEE WAX;
[0053] The unsaponifiable matter in the sunflower seed oil was obtained from a product called SOLINE purchased from Boshuo Company.
[0054] The purslane extract was sourced from Shanghai Jiyan Biotechnology Co., Ltd.
[0055] Gardenia fruit extract is sourced from Shanghai Jiyan Biotechnology Co., Ltd.;
[0056] β-glucan was obtained from a product called SC-GLUCAN purchased from Baron & Co.
[0057] Calendula flower extract was obtained from the product MARIGOLD EXTRACT purchased from Bailande; Ophiopogon japonicus root extract was obtained from the product AD-RESYL purchased from SILAB.
[0058] Flaxseed extract was obtained from a product called Lipigenine purchased from Ashland.
[0059] The extract of Boswellia carterii resin was obtained from a product called BOSEXIL purchased from Givaudan.
[0060] Examples 1-4, Comparative Examples 1-4
[0061]
[0062]
[0063] Note: All examples and comparative examples above are based on 100 parts by weight.
[0064] Its preparation method is as follows:
[0065] (1) Water, humectant, and thickener are mixed at 82°C to obtain an aqueous phase; water, betaine, and 1,2-pentanediol are mixed at 82°C to obtain a stabilizer; and skin-moisturizing oil and emulsifier are mixed at 82°C to obtain an oil phase.
[0066] (2) Mix the aqueous phase material, stabilizer and oil phase material at 82℃ and homogenize for 10 min to obtain the first mixture;
[0067] (3) The first mixture was mixed with an antioxidant at 72°C to obtain a second mixture;
[0068] (4) Mix the second mixture with the skin conditioning agent at 40°C to obtain the final product.
[0069] In Comparative Example 2, when the amount of low-temperature active ingredient added was low, the viscosity of the high-temperature aqueous phase was thin, and high-temperature emulsification was successful. In Comparative Example 1, when the amount of low-temperature active ingredient added was further increased, high-temperature emulsification failed because a large amount of active ingredient needed to be added later, which occupied the amount of pure water in the high-temperature aqueous phase. The viscosity of the high-temperature aqueous phase increased, and the hydrophilic competitiveness of the emulsifier was relatively weak, thus leading to the failure of high-temperature emulsification.
[0070] Examples 1, 2, 3, and 4 address the phenomenon of high-temperature emulsification failure caused by increasing the amount of low-temperature active ingredient. When different proportions of stabilizer were added to the system, high-temperature emulsification was successful in all cases. Comparing Comparative Examples 3 and 4 of this invention, with the same amount of low-temperature active ingredient, adding only 1,2-pentanediol aqueous solution or betaine aqueous solution resulted in high-temperature emulsification failure. This indicates that betaine and 1,2-pentanediol are both indispensable in the composition; only simultaneous addition can help improve the high-temperature emulsification stability of the formulation.
[0071] Test Example 1
[0072] Test samples: Example 1, Comparative Example 1
[0073] Test method: The test samples were compared using a LEICA DM2700 M polarizing microscope.
[0074] Depend on Figure 1 and Figure 2 It can be seen that the high-temperature emulsification of the material in Example 1 of this invention resulted in emulsified particles with smaller particle size and uniform distribution, while the high-temperature emulsification of the material in Comparative Example 1 did not result in obvious emulsified particles, and the oil phase remained in an agglomerated state. Figure 3 and Figure 4It can be seen that the material after high-temperature emulsification in Example 1 of the present invention exhibits a fine and glossy state, while the material after high-temperature emulsification in Comparative Example 1 exhibits water-oil separation and a coarse state. Figure 5 and Figure 6 It can be seen that although during the cooling process, due to the increased hydrophilicity of the emulsifier, some of the oil phase in the material of Comparative Example 1 was encapsulated to form an O / W structure, only a few emulsion particles were formed, and the emulsion particle size was very large and unevenly distributed. Most of the oil phase was still in an agglomerated state. In contrast, the finished product of the formulation in Example 1 had a smaller emulsion particle size and a more uniform distribution.
[0075] Test Example 2
[0076] Stability test record
[0077] Test samples: Example 1, Comparative Example 1
[0078] Test method: The products obtained in the examples were tested at temperatures of -15℃, 5℃, 25℃, 40℃, and 49℃, and the results were recorded. The results of Example 1 are shown in Table 1, and the results of Comparative Example 1 are shown in Table 2.
[0079] Table 1
[0080]
[0081] Table 2
[0082]
[0083]
[0084] According to Tables 1 and 2, it can be seen that after 90 days of testing at temperatures of -15℃, 5℃, 25℃, 40℃, and 49℃, the product of Example 1 showed no oil-water separation after returning to room temperature, and its properties were not significantly different from those before the experiment. In contrast, the formulation product of Comparative Example 1 showed varying degrees of oil-water separation at each testing temperature. In summary, this indicates that the product of Example 1 has better long-term stability.
[0085] In today's era of functional skincare products, some formulations require the addition of large amounts of active ingredients, thus consuming significant amounts of pure water. This invention addresses the issue of decreased emulsification efficiency of some polyoxyethylene nonionic emulsifiers in these cosmetic formulations under high-temperature conditions. It uses a combination of betaine and 1,2-pentanediol as a stabilizer, with water as a solvent, added to the system during high-temperature emulsification to improve the high-temperature emulsification stability of the formulation. The resulting O / W formulation exhibits excellent stability. Compared to adding polymeric thickeners at low temperatures, which can lead to complex processes and the risk of incomplete swelling of the thickener powder, using the combination of betaine and 1,2-pentanediol as a stabilizer is a simpler and risk-free process. Furthermore, compared to adding high-HLB emulsifiers to aid emulsification, which can increase the irritation of the formulation, the introduction of betaine helps improve the moisturizing and mildness of the formulation.
[0086] The applicant declares that this invention illustrates the application of a stabilizer in improving the high-temperature emulsification stability of cosmetics through the above embodiments, but this invention is not limited to the above embodiments, that is, it does not mean that this invention must rely on the above embodiments to be implemented. Those skilled in the art should understand that any improvements to this invention, equivalent substitutions of the raw materials of this invention, addition of auxiliary components, and selection of specific methods, etc., all fall within the protection scope and disclosure scope of this invention.
[0087] The preferred embodiments of the present invention have been described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the scope of the technical concept of the present invention, various simple modifications can be made to the technical solution of the present invention, and these simple modifications all fall within the protection scope of the present invention.
[0088] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not describe the various possible combinations separately.
Claims
1. The application of a stabilizer in improving the high-temperature emulsification stability of cosmetics, characterized in that, The stabilizer is a combination of betaine and 1,2-pentanediol in a mass ratio of (1-5):(1-5); The cosmetics mentioned are cosmetics that use polyoxyethylene nonionic emulsifiers.
2. The application according to claim 1, characterized in that, The stabilizer in the cosmetic product is 2-10 parts by weight.
3. The application according to claim 1, characterized in that, The stabilizer is added to the system using water as a solvent during high-temperature emulsification.