A kind of insecticide composition containing flubendiamide

Abstract

The present invention belongs to the technical field of pesticide compounding, and relates to an insecticidal composition containing flubendiamide and an application thereof. The composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is flubendiamide and the active ingredient B is trifluoromethylpyralid. The composition and the preparation thereof of the present invention can effectively prevent and control a variety of plant-feeding pests, delay the development of pest resistance, and reduce the use of chemical pesticides.

Description

[0001] This invention application is a divisional application with application number 2022113843471, application date January 13, 2022, and invention name “A pesticidal composition containing flubendiamide”. Technical Field

[0002] The invention belongs to the technical field of pesticides, and particularly relates to an application of a flubendiamide-containing insecticidal composition in preventing and controlling herbivorous pests. Background Art

[0003] Flufenac is a compound independently developed by our company. The compound patent (CN106977494B) was authorized on April 30, 2021, and the ISO international common name was obtained in June 2021. Flufenac belongs to the benzamide insecticide class, which can efficiently activate the insect nicotinic receptors and then excessively release calcium ions in the calcium store in the cell, causing paralysis and death of the insect. Flufenac chemical name: 3-bromo-1-(3-chloropyridin-2-yl)-N-[4,6-dichloro-3-fluoro-2-(methylaminoformyl)phenyl]-1H-pyrazole-5-carboxamide, CAS registration number is 2129147-03-9, molecular formula: C 17 H 10 BrCl3FN5O2, relative molecular mass (according to the 2009 international relative atomic mass): 521.56, melting point: 238℃~240℃, solubility in water is 0.711mg / L.

[0004] In the actual process of agricultural production, the most common problem of pest control is the development of pest resistance. Compounding different varieties of ingredients is a very common method for controlling resistant pests. Compounding different ingredients is used to determine whether a certain compound is synergistic, additive, or antagonistic based on the actual application results. In most cases, the compounding effect of pesticides is additive, and there are fewer cases of true synergism, especially compounds with very obvious synergistic effects and high co-toxicity coefficients. After research by the inventors, it was found that compounding flubendiamide with diafenthiuron, tolfenpyrad, and trifluoromethylpyrifos can produce unexpected synergistic effects, and related reports on the compounding of flubendiamide with diafenthiuron, tolfenpyrad, and trifluoromethylpyrifos have not yet been published. Summary of the Invention

[0005] The purpose of the present invention is to provide an insecticidal composition containing flubendiamide which has a synergistic effect, low use cost and good prevention effect.

[0006] A flufenacet-containing insecticidal composition comprising an active ingredient A and an active ingredient B, wherein the active ingredient A is flufenacet and the active ingredient B is any one of diafenthiuron, tolfenpyrad and flupyralid.

[0007] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:60 to 50:1;

[0008] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:60, 1:50, 1:45, 1:40, 1:35, 1:30, 1:25, 1:20, 1:15, 1:10, 1:5, 1:3, 1:2, 1:1, 2:1, 3:1, 5:1, 10:1, 15:1, 20:1, 25:1, 30:1, 35:1, 40:1, 45:1, and 50:1;

[0009] Furthermore, the mass ratio of flufenacet to diafenthiuron is 1:40 to 45:1;

[0010] Furthermore, the mass ratio of flufenacet to diafenthiuron is 1:20 to 35:1;

[0011] Furthermore, the mass ratio of flufenacet to diafenthiuron is 1:10 to 35:1;

[0012] Furthermore, the mass ratio of flufenacet to diafenthiuron is 1:1 to 15:1;

[0013] Furthermore, the mass ratio of flufenacet to diafenthiuron is 3:1 to 15:1;

[0014] Furthermore, the mass ratio of flufenacet to tolfenpyrad is 1:60 to 40:1;

[0015] Furthermore, the mass ratio of flufenacet to tolfenpyrad is 1:25 to 20:1;

[0016] Furthermore, the mass ratio of flufenacet to tolfenpyrad is 1:3 to 5:1;

[0017] Furthermore, the mass ratio of flubendiamide to flupyralid is 1:60 to 25:1;

[0018] Furthermore, the mass ratio of flubendiamide to flupyralid is 1:25 to 10:1;

[0019] Furthermore, the mass ratio of flubendiamide to flupyralid is 1:20 to 3:1;

[0020] Furthermore, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1% to 80 wt%;

[0021] Furthermore, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 5% to 50 wt%;

[0022] In an embodiment, the sum of the contents of the active ingredient A and the active ingredient B in the insecticidal composition is 10 to 30 wt%, for example, the sum of the contents of the active ingredient A and the active ingredient B in the insecticidal composition is 15 wt%, 16 wt%, 18 wt%, 20 wt%, 22 wt%, or 32 wt%.

[0023] The insecticide composition of the present invention can be prepared by a common processing method known to those skilled in the art, that is, after mixing the active substance with a liquid solvent or a solid carrier, one or more surfactants such as a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a stabilizer, etc. are added;

[0024] Furthermore, the wetting agent is selected from a mixture of one or more of sodium lauryl sulfate, sodium dodecylbenzene sulfonate, lakai powder BX, wetting and penetrating agent F, saponin powder, silkworm excrement or soapberry powder;

[0025] Furthermore, the dispersant is selected from a mixture of one or more of polycarboxylates, lignin sulfonates, alkylphenol polyoxyethylene ether formaldehyde condensate sulfates, alkylbenzene sulfonate calcium, naphthalenesulfonic acid formaldehyde condensate sodium salts, alkylphenol polyoxyethylene ether phosphates, fatty amine polyoxyethylene ethers, fatty acid polyoxyethylene ethers or glycerol fatty acid ester polyoxyethylene ethers;

[0026] Furthermore, the emulsifier is selected from Nongru 500# (calcium alkylbenzene sulfonate), OP series phosphate (nonylphenol polyoxyethylene ether phosphate), 600# phosphate (phenylphenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether sulfate ammonium salt, alkyl diphenyl ether disulfonic acid magnesium salt, triethanolamine salt, Nongru 400# (benzyl dimethylphenol polyoxyethyl ether), Nongru 700# (alkylphenol formaldehyde resin polyoxyethyl ether), Ningru 36# (phenylethylphenol formaldehyde resin polyoxyethylene ether), A mixture of one or more of the following: Nongru 1600# (phenylethylphenol polyoxyethylene polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), BY series (castor oil polyoxyethylene ether), Nongru 33# (alkylaryl polyoxyethylene polyoxypropylene ether), Span series (sorbitan monostearate), Tween series (sorbitan fatty acid ester polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether);

[0027] Furthermore, the thickener is selected from a mixture of one or more of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or magnesium aluminum silicate;

[0028] Furthermore, the disintegrant is selected from a mixture of one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate;

[0029] Furthermore, the antifreeze agent is selected from a mixture of one or more of ethylene glycol, propylene glycol, glycerol or urea;

[0030] Furthermore, the defoaming agent is selected from silicone oil, silicone compounds, C 10 ~C 20 Saturated fatty acid compounds or C8~C 10 A mixture of one or more fatty alcohol compounds;

[0031] Furthermore, the solvent is selected from a mixture of one or more of N,N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octylpyrrolidone, ethanolamine, triethanolamine, isopropylamine, N-methylpyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, ethanolamine, isopropylamine, ethyl acetate or acetonitrile;

[0032] Furthermore, the stabilizer is selected from a mixture of one or more of epoxy soybean oil, epichlorohydrin, BHT, ethyl acetate, and triphenyl phosphate;

[0033] Furthermore, the penetrant is selected from a mixture of one or more of penetrant JFC (fatty alcohol polyoxyethylene ether), penetrant T (diisooctyl maleate sulfonate), azone or silicone;

[0034] Furthermore, the carrier is a solvent or a filler or a mixture thereof;

[0035] Furthermore, the filler is selected from a mixture of one or more of kaolin, diatomaceous earth, bentonite, attapulgite, white carbon black, starch or light calcium carbonate;

[0036] The above substances are all commercially available.

[0037] The insecticide composition of the present invention can be processed into any pesticide-acceptable dosage form as needed, and the dosage form of the insecticide composition is selected from any one of powders, granules, soluble powders, soluble granules, soluble tablets, water-dispersible granules, wettable powders, microcapsule granules, water-dispersible tablets, microcapsule suspensions, dispersible solutions, emulsifiable concentrates, emulsions in water, microemulsions, suspensions, suspoemulsions, and soluble solutions;

[0038] Furthermore, the preferred formulations of the insecticide composition are: suspension concentrate, emulsifiable concentrate, wettable powder;

[0039] Furthermore, the insecticide composition is prepared into a suspension concentrate, which contains the following components and contents: active ingredient A 0.5% to 50%, active ingredient B 0.5% to 50%, dispersant 1% to 10%, wetting agent 1% to 10%, defoaming agent 0.01% to 2%, thickener 0% to 2%, antifreeze agent 0% to 8%, and deionized water to make up the balance;

[0040] Furthermore, the insecticide composition is prepared into an emulsifiable concentrate, which contains the following components and contents: active ingredient A 0.5% to 50%, active ingredient B 0.5% to 50%, emulsifier 1% to 10%, and solvent making up the balance;

[0041] Furthermore, the insecticide composition is prepared into a wettable powder, which contains the following components and contents: active ingredient A 0.5% to 60%, active ingredient B 0.5% to 80%, dispersant 1% to 12%, wetting agent 1% to 8%, and filler to make up the balance;

[0042] The present invention also provides the use of the above-mentioned insecticidal composition containing flubendiamide in preventing and controlling herbivorous pests in agriculture, forestry and gardening;

[0043] Furthermore, the herbivorous pests are Lepidoptera, Thysanoptera, and Hemiptera pests;

[0044] The Lepidoptera pests include: Adoxophyes spp., Adoxophyes orana, Agrotis spp. (cutworms), Agrotis ipsilon (black cutworm), Alabama argillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navelorangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma ta lis, Archips argyrospila (fruittree leafroller), Archips rose leafroller, and A. rosana (rose leaf roller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrana (orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara (rice leaf folder), Bucculatrix thurberiella (cotton leaf perforator), Caloptilia spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot borer), Choristoneura rosaceana (obliquebanded rose leaf roller), leafroller)), Chrysodeixis spp.), Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borer), borers), Diatraea spp. (stalk borers), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwester corn borer), Earias spp. (cotton bollworm), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella) (almond moth), Ephestia elutella (tobbacomoth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp.), Epinotia aporema, Erionotathrax (banana skipper), Eupoecilia ambiguella (grapeberry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemblerers), Grapholitamolesta (oriental fruit moth), Hedylepta indicate (bean leaf webber), Helicoverpa spp. (snottle moths), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis budworm ( virescens), Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella (tomato borer), Leucinodes orbonalis (eggplant borer), Leucoptera malifoliella (moth), Lithocollectis spp. (grape fruit moth), Lobesia botrana (grape fruit moth), Loxagrotis spp. (grape fruit moth), Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), bagworm) and Malacosoma spp.) (tent caterpillars), Mamestra brassicae (cabbage armyworm), Maruca testulalis (bean pod borer), Metisa plana (bagworm), Mythimna unipuncta (true armyworm), Neoleucinodes elegantalis, Nymphula depunctalis (three-spotted water borer), Operophtherabrumata (winter looper), Ostrinia nubilalis (European corn borer), Oxydia vesulia, Pandemis cerasana (common currant tortrix), Pandemis heparana (brown apple tortrix), Papilio demodocus (African swallowtail), Pectinophora gossypiella (pink bollworm), (Bollworm), Peridroma species (pp.), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp., Pieris rapae, Plathypena scabra, Plodia interpunctella, Plutellaxylostella (diamondback moth), Polychrosis viteana (grapeberry moth), Prays endocarpa, Prays olive moth oleae) (olive moth), Pseudaletia spp.(Spodoptera litura Fabricius), Pseudaletia unipunctata (armyworm), Pseudoplusia includes (, Rachiplusia nu), Chilo suppressalis (Walker), Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp., Spodoptera exigua, Spodoptera frugiperda fugiperda), Spodoptera oridania (southern armyworm), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (cabbage worm), Pieris rapae Linne (cabbage worm), and Tuta absoluta.

[0045] The Thysanoptera pests include: Thrips palmi Karny, Thrips tabaci, Frankliniella fusca (tobacco thrips), Frankliniella occidentalis (western flower thrips), Frankliniella shultzei, Frankliniella williamsi (corn thrips), Heliothrips haemorrhaidalis (greenhouse thrips), Riphiphorothrips cruentatus, Scirtothrips spp., Scirtothrips citri (citrus thrips), Scirtothrips spp. dorsalis) (yellow tea thrips), Taeniothrips rhopalantennalis, and Thrips spp.;

[0046] The Hemiptera pests include: Acrosternum hilare (green stink bug), Blissus leucopterus (chinch bug), Calocoris norvegicus, Acrosternum hilare (green stink bug), Blissus leucopterus (chinch bug), Calocoris norvegicus, (aphids, scales, whiteflies, leafhoppers), Acrythosiphon pisum (pea aphid), Adelges spp., Aleurodes proletella, Aleurodicus disperses), Aleurothrixus floccosus (wooly whitefly), Aluacaspis spp., Aonidiella aurantii, Aphis spp., Aphis gossypii (cotton aphid), Aphis pomi, Aulacorthum solani (foxglove aphid), Bemisia spp. (whitefly), Bemisia argentifolii, Bemisia tabaci (sweet potato whitefly), Brachycolus noxius, Brachycorynella asparagi (asparagus aphid), Brevennia rehi, Brevicoryne brassicae), Ceroplastes spp., Ceroplastes rubens (red wax scale), Chionaspis spp., Chrysomphalus spp., Dysaphis plantaginea (rosy apple aphid), Empoasca spp.), Eriosomalanigerum (apple cotton aphid), Icerya purchasi (cottony cushion scale), Idioscopus nitidulus (mango leafhopper), Laodelphaxstriatellus (lime planthopper), Lepidosaphes spp., Macrosiphum spp., Macrosiphum euphorbiae, Macrosiphum granarium, Macrosiphum rosae (rose aphid), Macrosteles quadrilineatus (aster leafhopper), Mahanarva frimbiolata, Metopolophium dirhodum, Mictis longicornis, Myzus spp., Myzus persicae (green peach aphid), aphid), Nephotettix spp., Nephotettix cinctipes (green leafhopper), Nilaparvata lugens, Parlatoria pergandii, Peregrinus maidis (corndelphacid), Philaenus spp., Phylloxeravitifoliae (grape phylloxera), Physokermes piceae (spruce bud scale), Planococcus spp. (mealybugs), Pseudococcus spp. (mealybugs), Pseudococcus brevipes (pineapple mealybugs), mealybug), Quadraspidiotus perniciosus (San Josescale), Rhopalosiphum spp.), Rhopalosiphum maida (corn leaf aphid), Rhapalosiphum padi (oat bird-cherry aphid), Saissetia spp., Saissetia oleae, Schizaphis graminum (greenbug), Sitobion avenae (English grain aphid), Sogatella furcifera, Therioaphis spp., Toumeyella spp., Trialeurodes spp., and Trialeurodes vaporariorum;

[0047] Furthermore, the lepidopteran pests include diamondback moth, beet armyworm, Spodoptera litura, striped stem borer, cotton bollworm, and cabbage worm;

[0048] Furthermore, the Thysanoptera pests include Thrips tabaci, Thrips palmi, Thrips occidentalis, Thrips occidentalis, Thrips truncatus;

[0049] Furthermore, the Hemiptera pests include whiteflies, rice planthoppers, and aphids.

[0050] The present invention also provides a method for using the insecticidal composition containing flubendiamide as described above, specifically applying an effective dose to the pests to be controlled or the medium in which they grow.

[0051] The advantages of the present invention are:

[0052] (1) Flufenacet has a significant synergistic and lasting effect when combined with any of diafenthiuron, tolfenpyrad, and flupyralid;

[0053] (2) It has a high control effect on Lepidoptera, Thysanoptera, and Hemiptera pests of crops;

[0054] (3) Reduce the amount of pesticides used, reduce the amount of pesticide residues on crops, and alleviate environmental pollution;

[0055] (4) Safe for humans and animals, and environmentally friendly.

[0056] Specific implementation cases

[0057] Preparation Example 1: 22% flufenacet-difenac·diafenthiuron suspension concentrate (10:1)

[0058] Formula: Flufenac 20%, diafenthiuron 2%, lignin sulfonate 3.5%, BX4%, silicone oil 0.4%, soap powder 0.2%, polyvinyl alcohol 1.5%, ethylene glycol 2.5%, and deionized water to make up the balance.

[0059] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added and mixed evenly, and the suspension is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0060] Preparation Example 2: 32% flufenacet-difenacil·diafenthiuron suspension concentrate (15:1)

[0061] Formula: flufenacet 30%, diafenthiuron 2%, naphthalenesulfonate amol NN 8906 4%, opening powder BX 4.5%, silicone oil 0.5%, polyvinyl alcohol 0.8%, ethylene glycol 2.5%, and deionized water to make up the balance.

[0062] Preparation method: Same as Preparation Example 1.

[0063] Preparation Example 3: 18% flufenacet-difenac·diafenthiuron suspension concentrate (8:1)

[0064] Formula: flufenacet 16%, diafenthiuron 2%, lignin sulfonate 2%, alkylphenol polyoxyethylene ether phosphate 5%, silicone oil 0.6%, polyvinyl alcohol 1.2%, propylene glycol 4%, and deionized water to make up the balance.

[0065] Preparation method: Same as Preparation Example 1.

[0066] Preparation Example 4: 15% flufenacet·tolfenpyrad suspension concentrate (2:1)

[0067] Formula: Flufenac 10%, Tolfenpyrad 5%, Alkylphenol Polyoxyethylene Ether Phosphate 5%, Wetting and Penetrating Agent F 1.5%, Soapberry Powder 0.5%, Silicone Oil 0.6%, Xanthan Gum 0.3%, Propylene Glycol 3%, Deionized Water to Make Up the Balance.

[0068] Preparation method: Same as Preparation Example 1.

[0069] Preparation Example 5: 16% flufenacet·tolfenpyrad suspension concentrate (3:1)

[0070] Formula: flubendiamide 12%, tolfenpyrad 4%, lignin sulfonate 2%, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate 3%, wetting and penetrating agent F 1.5%, soapberry powder 0.5%, silicone oil 0.5%, magnesium aluminum silicate 1.2%, ethylene glycol 3%, and deionized water to make up the balance.

[0071] The preparation method is the same as that of Preparation Example 1.

[0072] Preparation Example 6: 20% flufenacet·tolfenpyrad suspension concentrate (1:1)

[0073] Formula: Flufenac 10%, Tolfenpyrad 10%, Alkylphenol Polyoxyethylene Ether Phosphate 3.8%, Wetting Penetrant F 1.5%, Soapberry Powder 0.5%, Silicone Oil 0.7%, Xanthan Gum 0.3%, Ethylene Glycol 2.5%, Deionized Water to Make Up the Balance.

[0074] Preparation method: Same as Preparation Example 1.

[0075] Preparation Example 7: 22% flufenacet·trifluoromethylpyrifos suspension (1:10)

[0076] Formula: flufenac 2%, trifluoromethylpyrifos 20%, lignin sulfonate 2%, alkylaryl polyoxyethylene polyoxypropylene ether 3%, BX powder 4.4%, silicone oil 0.5%, xanthan gum 0.3%, ethylene glycol 4.8%, and deionized water to make up the balance.

[0077] Preparation method: Same as Preparation Example 1.

[0078] Preparation Example 8: 18% flubendiamide·trifluoromethylpyrifos suspension (1:5)

[0079] Formula: flubendiamide 3%, trifluoromethylpyrifos 15%, alkylphenol polyoxyethylene ether phosphate 6.2%, sodium lauryl sulfate 2%, silicone oil 0.7%, xanthan gum 0.3%, urea 4.5%, and deionized water to make up the balance.

[0080] Preparation method: Same as Preparation Example 1.

[0081] Preparation Example 9: 32% flufenacet·trifluoromethylpyrifos suspension (1:15)

[0082] Formula: flufenac 2%, trifluoromethylpyrifos 30%, alkylphenol polyoxyethylene ether phosphate 5%, opening powder BX 4%, silicone oil 0.9%, bentonite 1%, xanthan gum 0.2%, ethylene glycol 3%, and deionized water to make up the balance.

[0083] Preparation method: Same as Preparation Example 1.

[0084] Preparation Example 10: 18% flufenacet-difenacil emulsifiable concentrate (8:1)

[0085] Formula: Flufenac 8%, diafenthiuron 10%, tristyrylphenol polyoxyethylene ether 12%, calcium dodecylbenzenesulfonate 3%, cyclohexanone 20%, propylene carbonate 10%, and solvent oil to make up the balance.

[0086] Preparation method: Dissolve the active ingredient in an organic solvent according to a certain formula ratio, then add a certain amount of emulsifier and other additives, and stir and mix to prepare a homogeneous transparent oily liquid.

[0087] Preparation Example 11: 16% flubendiamide·trifluoromethylpyrifos emulsifiable concentrate (1:15)

[0088] Formula: flubendiamide 1%, trifluoromethylpyrifos 15%, sorbitan fatty acid ester polyoxyethylene ether 13%, calcium dodecylbenzenesulfonate 2%, acetophenone 24%, DMF 5%, and xylene to make up the balance.

[0089] Preparation method: Same as Preparation Example 10.

[0090] Preparation Example 12: 33% flufenacet·diafenthiuron wettable powder (10:1)

[0091] Formula: Flufenac 30%, diafenthiuron 3%, naphthalenesulfonate formaldehyde condensate 8%, BX powder 3%, kaolin 12%, and diatomaceous earth to make up the balance.

[0092] Preparation method: According to the formula ratio of the embodiment, the active ingredients flufenacet and diafenthiuron are added to a carrier, and a surfactant and other functional additives are added thereto, mixed, and then air flow-milled and mixed again to prepare a wettable powder.

[0093] Example 13: 24% flufenacet·diafenthiuron wettable powder (5:1)

[0094] Formula: flubendiamide 20%, tebufenozide 4%, sodium lignin sulfonate 7%, dispersant NNO 4%, opening powder BX 3%, white carbon black 10%, and kaolin to make up the balance.

[0095] Preparation method: Same as Preparation Example 12.

[0096] 97% diafenthiuron technical, 98% tolfenpyrad technical, 91% flupyralid technical, and 90% flufenacet technical are all provided by the Group's R&D center.

[0097] Indoor activity test case:

[0098] Test method:

[0099] Thysanoptera adults: glass roller tube method;

[0100] Test insect age: Use sensitive populations raised indoors for multiple generations, select healthy and consistent female adults of Thysanoptera,

[0101] After rolling the glass tube evenly with 250 μl of the drug solution, use a cork punch to punch the cabbage leaves into 1.5 cm diameter discs. Using tweezers, place the fresh cabbage slices in the drug solution for 10 seconds before removing them. After the solution is allowed to dry naturally, place the cabbage slices in the glass tube. Then, use a sucker to suck 15 adult female Thysanoptera into the glass tube and seal it with a 200-mesh gauze. Each treatment is repeated four times, with a blank treatment serving as a control. The treated insects are reared in an artificial intelligence culture chamber at 26 ± 1°C, a photoperiod of L:D = 16h:8h, and a relative humidity of 60%.

[0102] Lepidoptera larvae: a combination of leaf and insect dipping;

[0103] Test Insect Age: Using a sensitive population reared indoors for multiple generations, healthy, consistent second-instar Lepidoptera larvae were selected. Fresh cabbage pieces were placed in the drug solution using tweezers and immersed for 10 seconds before removal. After the solution dried naturally, the cabbage pieces were placed in a Petri dish lined with moisturizing filter paper. Twenty second-instar Lepidoptera larvae were placed in the drug solution for 5 seconds. Excess drug solution was then absorbed with filter paper, and the test insects were placed in a Petri dish containing leaves soaked at the corresponding concentration. Each treatment was replicated four times, with a blank treatment serving as a control. The treated test insects were maintained in an artificial intelligence incubator at 26±1°C, a photoperiod of L:D = 16h:8h, and a relative humidity of 60%.

[0104] After treatment with the pesticide, the mortality of the test insects was investigated 48 hours later. The criterion for judging the death of the test insects was obvious shrinkage of the insect body or inability to crawl normally after being pricked with a needle. The number of dead insects was recorded.

[0105] Data statistics and analysis: If the blank control mortality rate is less than 5%, no correction is required; if the blank control mortality rate is 5% to 10%, correction is required; if the blank control mortality rate is above 10%, the test needs to be repeated.

[0106] The calculation formula is as follows:

[0107]

[0108]

[0109] LC 50 The agent with a relatively small value is the standard agent, and its toxicity index TI is 100.

[0110]

[0111]

[0112] Theoretical toxicity index of the mixture TTI = TI A ×P A +TI B ×P B

[0113]

[0114] Where: P A 、P B are the weight ratios of active ingredients A and B in the composition, respectively.

[0115] Data statistical analysis was performed using IBM Spss statistics 20 software.

[0116] Indoor Example 1

[0117] Results of toxicity test of flufenacet and diafenthiuron against thrips

[0118] Table 1 Analysis of the results of toxicity test of flufenacet and diafenthiuron against thrips

[0119]

[0120] As shown in Table 1, the co-toxicity coefficients of flufenacet and diafenthiuron against thrips were greater than 80 at a ratio of 1:60 to 50:1, indicating that the two exhibited additive or synergistic effects when mixed within the range of 1:60 to 50:1, and no antagonistic effect occurred.

[0121] When the weight ratio of fluchlorfenapyr to diafenthiuron was between 1:40 and 45:1, the co-toxicity coefficients were all greater than 120, indicating that the two exhibited a synergistic effect when mixed within this weight ratio range; when the weight ratio of fluchlorfenapyr to diafenthiuron was between 1:10 and 35:1, the co-toxicity coefficients were all greater than 130, indicating that the two exhibited significant synergism within this mixing weight ratio range; when the weight ratio of fluchlorfenapyr to diafenthiuron was between 3:1 and 15:1, the co-toxicity coefficients were all greater than 150, indicating that the synergistic effect of the two was more prominent within this mixing weight ratio range.

[0122] Indoor Example 2

[0123] Results of toxicity test of flufenacet and diafenthiuron against Pieris rapae

[0124] Table 2 Analysis of the toxicity test results of flufenacet and diafenthiuron against Pieris rapae

[0125]

[0126]

[0127] As shown in Table 2, the co-toxicity coefficients of flufenacet and diafenthiuron against Pieris rapae at a ratio of 1:35 to 35:1 were greater than 120, showing a synergistic effect.

[0128] When the weight ratio of flufenacet and diafenthiuron was between 1:20 and 35:1, the co-toxicity coefficient was greater than 130, indicating that the two showed obvious synergy within this mixing weight ratio range; when the weight ratio of flufenacet and diafenthiuron was between 1:1 and 15:1, the co-toxicity coefficient was greater than 150, indicating that the synergistic effect of the two was more prominent within this mixing weight ratio range.

[0129] Indoor Example 3

[0130] Results of toxicity test of flufenacet and tolfenpyrad against thrips

[0131] Table 3 Analysis of the results of toxicity determination of flufenacet and tolfenpyrad against thrips

[0132]

[0133]

[0134] As shown in Table 3, the co-toxicity coefficients of flufenacet and tolfenpyrad against thrips were greater than 80 at a ratio of 1:60 to 50:1, indicating that the two exhibited additive or synergistic effects when mixed within the range of 1:60 to 50:1, and no antagonistic effect occurred.

[0135] When the weight ratio of fluchlorfenapyr and tolfenpyrad is between 1:60 and 40:1, the co-toxicity coefficient is greater than 120, indicating that the two exhibit a synergistic effect when mixed within this weight ratio range; when the weight ratio of fluchlorfenapyr and tolfenpyrad is between 1:25 and 20:1, the co-toxicity coefficient is greater than 130, indicating that the two exhibit obvious synergism within this mixing weight ratio range; when the weight ratio of fluchlorfenapyr and tolfenpyrad is between 1:3 and 5:1, the co-toxicity coefficient is greater than 150, indicating that the synergistic effect of the two is more prominent within this mixing weight ratio range.

[0136] Indoor Example 4

[0137] Results of toxicity test of flufenacet and tolfenpyrad against Spodoptera litura

[0138] Table 4 Analysis of the toxicity test results of flufenacet and tolfenpyrad on Spodoptera litura

[0139]

[0140] As shown in Table 4, the co-toxicity coefficients of flufenacet and tolfenpyrad against Spodoptera litura were greater than 120 at a weight ratio of 1:50 to 50:1, indicating that the mixture exhibited a synergistic effect. When the weight ratio of flufenacet to tolfenpyrad was 1:5 to 40:1, the co-toxicity coefficients were greater than 130, indicating that the two exhibited significant synergy within this weight ratio range. When the weight ratio of flufenacet to tolfenpyrad was 1:2 to 10:1, the co-toxicity coefficients were greater than 150, indicating that the synergistic effect of the two was more prominent within this weight ratio range.

[0141] Indoor Example 5

[0142] Results of toxicity test of flufenacet and triflumuron against thrips

[0143] Table 5 Analysis of the toxicity test results of flubendiamide and trifluoromethylpyrifos against thrips

[0144]

[0145] As shown in Table 5, the co-toxicity coefficients of flubendiamide and trifluoromethylpyrifos against thrips were greater than 80 at a ratio of 1:60 to 50:1, indicating that the two exhibited additive or synergistic effects when mixed within the range of 1:60 to 50:1, and no antagonistic effect occurred.

[0146] When the weight ratio of flubendiamide and trifluoromethylpyrifos is between 1:60 and 25:1, the co-toxicity coefficient is greater than 120, indicating that the two exhibit a synergistic effect when mixed within this weight ratio range; when the weight ratio of flubendiamide and trifluoromethylpyrifos is between 1:25 and 10:1, the co-toxicity coefficient is greater than 130, indicating that the two exhibit obvious synergism within this mixing weight ratio range; when the weight ratio of flubendiamide and trifluoromethylpyrifos is between 1:20 and 3:1, the co-toxicity coefficient is greater than 150, indicating that the synergistic effect of the two is more prominent within this mixing weight ratio range.

[0147] Field Example 1

[0148] Field trials for controlling eggplant thrips

[0149] Test crops: Eggplant, variety Dalong;

[0150] Test subjects: Thrips palmi Karny;

[0151] The experiment was conducted at the Yifengdian eggplant planting base in Qingdao City, Shandong Province. The experimental fields had medium fertility and consistent cultivation conditions.

[0152] The experiment was conducted with 7 mixed treatments, 5 control treatments, 4 replicates, random arrangement, and a plot area of 20 m 2 .

[0153] Application period: The test was carried out during the peak period of thrips outbreak, with one application and a water volume of 750 kg / hm2. 2 .

[0154] The pesticide application equipment is a WS-16D Guardian electric sprayer with a single fan-shaped mist nozzle and a working pressure of 0.15-0.4Mpa. The dosage is accurately measured according to the dosage requirements and the area of the plot.

[0155] When preparing the medicine, first add one-third of the actual water volume into the sprayer, add a little water to a small measuring cup to stir the medicine evenly, pour it into the sprayer, and finally add the remaining water and mix well.

[0156] When applying pesticides, spray the control first, and then proceed from low concentration to high concentration in sequence, using the constant spray method, spraying at a constant speed and evenly according to the calculated pace. When changing different pesticides, first clean the sprayer three times and spray out all the water in the spray boom.

[0157] The weather was good during the test. On the day of application, the average daily temperature was 22°C, the highest temperature was 29°C, the lowest temperature was 18°C, and the relative humidity was 70%.

[0158] Survey method: Survey the insect population base before applying pesticides. Hang 5 leaves on fixed plants in each plot for survey. The insect population before treatment should be no less than 200. Survey the number of live insects 1 day, 7 days and 14 days after applying pesticides.

[0159] Calculation method of drug efficacy: The drug efficacy is calculated according to the following formula:

[0160]

[0161]

[0162] During the experiment, eggplants in each treatment plot grew well and no phytotoxicity was observed in any treatment.

[0163] Table 6 Control effects of different pesticides on eggplant thrips in the field

[0164]

[0165]

[0166] Field Example 2

[0167] Field trials on controlling cabbage worms

[0168] Test crops: cabbage, variety: Early-maturing No. 15;

[0169] Test subjects: Pieris rapaeLinne;

[0170] The experiment was conducted at the Xiazhuang vegetable planting base in Chengyang District, Qingdao City, Shandong Province. The experimental fields had medium fertility and consistent cultivation conditions.

[0171] The experiment was conducted with 4 mixed treatments, 5 control treatments, 4 replicates, random arrangement, and a plot area of 20 m 2 The test was carried out at the early stage of the outbreak of Pieris rapae, with one application and a water consumption of 750 kg / hm2. 2 .

[0172] The pesticide application equipment is a WS-16D Guardian electric sprayer with a single fan-shaped mist nozzle and a working pressure of 0.15-0.4Mpa. The dosage is accurately measured according to the dosage requirements and the area of the plot.

[0173] When preparing the medicine, first add one-third of the actual water volume into the sprayer, add a little water to a small measuring cup to stir the medicine evenly, pour it into the sprayer, and finally add the remaining water and mix well.

[0174] When applying pesticides, spray the control first, and then proceed from low concentration to high concentration in sequence, using the constant spray method, spraying at a constant speed and evenly according to the calculated pace. When changing different pesticides, first clean the sprayer three times and spray out all the water in the spray boom.

[0175] The weather was good during the test. On the day of application, the average daily temperature was 23°C, the highest temperature was 30°C, the lowest temperature was 16°C, and the relative humidity was 65%.

[0176] Survey method: Investigate the insect population base before applying the pesticide. Select 10 cabbages in each plot for investigation. Investigate the number of live insects 3d, 7d, and 14d after applying the pesticide.

[0177] Calculation method of drug efficacy: The drug efficacy is calculated according to the following formula:

[0178]

[0179]

[0180] During the experiment, the cabbage in each treatment plot grew well and no phytotoxicity was observed in any treatment.

[0181] Table 7 Control effects of different pesticides on cabbage worms in the field

[0182]

[0183] Field Example 3

[0184] Field trials for controlling Spodoptera litura

[0185] Test crops: green onions, the variety is iron green onion;

[0186] Test subject: Spodoptera litura

[0187] The experiment was conducted at the green onion planting base in Zhuliang Town, Qingzhou City, Shandong Province. The experimental field had medium fertility and the cultivation conditions were consistent. The experiment was conducted with 4 treatments, 3 control treatments, 4 replicates, and random arrangement. The plot area was 20m 2 The test was carried out during the initial outbreak of Spodoptera litura, with one application.

[0188] The pesticide application equipment is a WS-16D Guardian electric sprayer with a single fan-shaped mist nozzle and a working pressure of 0.15-0.4Mpa. The dosage is accurately measured according to the dosage requirements and the area of the plot.

[0189] When preparing the medicine, first add one-third of the actual water volume into the sprayer, add a little water to a small measuring cup to stir the medicine evenly, pour it into the sprayer, and finally add the remaining water and mix well.

[0190] When applying pesticides, spray the control first, and then proceed from low concentration to high concentration in sequence, using the constant spray method, spraying at a constant speed and evenly according to the calculated pace. When changing different pesticides, first clean the sprayer three times and spray out all the water in the spray boom.

[0191] The weather was good during the test. On the day of application, the average daily temperature was 20℃, the highest temperature was 25℃, the lowest temperature was 15℃, and the relative humidity was 68%.

[0192] Survey method: Investigate the insect population base before applying the pesticide. Select 30 green onions in each plot for investigation. Investigate the number of live insects 1 day, 3 days, and 7 days after applying the pesticide.

[0193] Calculation method of drug efficacy: The drug efficacy is calculated according to the following formula:

[0194]

[0195]

[0196] During the experiment, it was observed that the green onions in each treatment plot grew well, and no phytotoxicity was observed in any treatment.

[0197] Table 8 Control effects of different pesticides on Spodoptera litura in the field

[0198]

[0199] The above embodiments are intended only to illustrate the technical concepts and features of the present invention. Their purpose is to enable those skilled in the art to understand the contents of the present invention and implement them accordingly. They are not intended to limit the scope of protection of the present invention. Any equivalent changes or modifications made based on the essence of the present invention are intended to be covered by the scope of protection of the present invention.

Claims

1. An insecticidal composition containing flubendiamide, characterized in that: The invention comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is flubendiamide and the active ingredient B is flupyralid, and the mass ratio of flubendiamide to flupyralid is 1:60 to 25:

1.

2. The insecticidal composition according to claim 1, characterized in that The mass ratio of flubendiamide to flupyralid is 1:25 to 10:

1.

3. The insecticidal composition according to claim 1, characterized in that The total weight of the insecticide composition is 100 wt %, and the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1 to 80 wt %.

4. The insecticidal composition according to claim 1, characterized in that The total weight of the insecticide composition is 100 wt%, and the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 5 to 50 wt%.

5. The insecticidal composition according to claim 1, characterized in that The insecticide composition further comprises an adjuvant, which is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a stabilizer, a penetrant and a carrier.

6. The insecticidal composition according to claim 1, characterized in that The insecticide composition can be processed into any agriculturally acceptable dosage form, selected from any one of powders, granules, soluble powders, soluble granules, soluble tablets, water-dispersible granules, wettable powders, microcapsule granules, water-dispersible tablets, microcapsule suspensions, dispersible liquids, emulsifiable concentrates, emulsions in water, microemulsions, suspensions, suspoemulsions, and soluble solutions.

7. The insecticidal composition according to claim 6, characterized in that The formulation of the insecticide composition is selected from any one of wettable powder, emulsifiable concentrate and suspension concentrate.

8. Use of the insecticidal composition according to any one of claims 1 to 7 in controlling herbivorous pests in agriculture, forestry and gardening, characterized in that: The herbivorous pests are Thysanoptera pests, including Thrips tabaci, Thrips palmi, Thrips occidentalis, Thrips occidentalis and Thrips occidentalis.

9. The use according to claim 8, characterized in that The insecticide composition is applied to the pests to be controlled or the medium where they grow in an effective dose.

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