A traditional Chinese medicine composition for promoting perineal wound healing and a preparation method thereof

Abstract

The application provides a traditional Chinese medicine composition for promoting perineal wound healing and a preparation method thereof. The traditional Chinese medicine composition for promoting perineal wound healing comprises dragon's blood, dandelion, aconite, angelica, raw south star, frankincense, corydalis, cortex moutan, white cardamom and wind-preventing plant. The traditional Chinese medicine composition for promoting perineal wound healing is suitable for postpartum women and has a remarkable curative effect on perineal wound healing, and can greatly shorten the wound healing time.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for promoting perineal wound healing and a preparation method thereof. BACKGROUND

[0002] During childbirth, the perineum of a puerpera is often damaged to form a laceration. In order to prevent the perineum of the puerpera from being lacerated and protect the pelvic floor muscles, a perineal lateral incision is often used in clinical practice. The perineal lateral incision refers to making an oblique incision in the perineum, which can be a lateral incision or a median incision. Generally, the postoperative wound is healed in about two weeks. However, the perineal laceration or the wound of the perineal lateral incision is often subjected to relatively large tension and traction due to the proximity of the perineum to the urethral orifice, the vaginal orifice and the anus, which is not conducive to wound healing. At the same time, urine, lochia and feces can easily irritate the wound and increase the risk of wound infection. In addition, the puerpera is more likely to have poor blood circulation after childbirth, which is also not conducive to wound healing. At present, the conventional wound treatment methods, such as potassium permanganate irrigation, have poor effects on perineal wound healing and a long healing time. SUMMARY

[0003] The present application aims to provide a traditional Chinese medicine composition for promoting perineal wound healing and a preparation method thereof, so as to solve the problems of poor wound healing effect and long healing time of the wound treatment in the prior art.

[0004] To solve the above technical problems, the technical solutions of the present application are as follows:

[0005] A traditional Chinese medicine composition for promoting perineal wound healing, comprising:

[0006] Dragon's blood, dandelion, aconite, angelica, raw south star, frankincense, corydalis, peony bark, white cardamom and windproof.

[0007] Preferably, the traditional Chinese medicine composition for promoting perineal wound healing comprises the following raw materials by weight:

[0008] Dragon's blood 100-200 parts, dandelion 80-120 parts, aconite 30-50 parts, angelica 50-80 parts, raw south star 20-40 parts, frankincense 80-120 parts, corydalis 50-80 parts, peony bark 30-50 parts, white cardamom 20-40 parts and windproof 10-30 parts.

[0009] Preferably, the traditional Chinese medicine composition for promoting perineal wound healing comprises the following raw materials by weight:

[0010] Dragon's blood 180 parts, dandelion 120 parts, aconite 40 parts, angelica 60 parts, raw south star 25 parts, frankincense 80 parts, corydalis 65 parts, peony bark 30 parts, white cardamom 30 parts and windproof 25 parts.

[0011] The application further provides a preparation method of the traditional Chinese medicine composition for promoting perineal wound healing, comprising the following steps: taking blood stasis, dandelion, aconite, angelica, raw south star, frankincense, corydalis, peony bark, white cardamom, and windproof, mixing uniformly, and preparing into a clinically acceptable preparation.

[0012] Preferably, the preparation method of the traditional Chinese medicine composition for promoting perineal wound healing comprises the following steps:

[0013] (1) taking blood stasis, dandelion, aconite, angelica, raw south star, peony bark, and white cardamom by weight parts, crushing, water decocting, concentrating, drying, and crushing to obtain a first extract;

[0014] (2) taking frankincense, corydalis, and windproof by weight parts, crushing, ethanol reflux extracting, concentrating, drying, and crushing to obtain a second extract;

[0015] (3) mixing the first extract and the second extract uniformly, and mixing with vaseline and polysorbate-80 uniformly to obtain the traditional Chinese medicine composition for promoting perineal wound healing.

[0016] Preferably, in step (1), 8-10 times of water is used for decocting for 2-4 hours.

[0017] Preferably, in step (1), the soaking temperature is 15-40 DEG C before water decocting.

[0018] Preferably, in step (2), the volume concentration of the ethanol is 40-60%, and the reflux extraction is performed for 1-2 hours.

[0019] Preferably, in step (1), the water decocting is performed for 1-5 times; and in step (2), the ethanol reflux extraction is performed for 1-5 times.

[0020] Preferably, in step (3), the mass ratio of the mixture of the first extract and the second extract to the vaseline and the polysorbate-80 is 10:(3-8):(1-2).

[0021] The above scheme of the application at least has the following beneficial effects:

[0022] The traditional Chinese medicine composition for promoting perineal wound healing provided by the application comprises blood stasis, dandelion, aconite, angelica, raw south star, frankincense, corydalis, peony bark, white cardamom, and windproof.

[0023] Blood stasis has the effects of dispersing blood stasis, relieving pain, stopping bleeding, and promoting skin healing, and can be used for treating contusion and injury, internal injury with blood stasis, uncontrolled bleeding after trauma, skin ulcer and abscess, and long-term non-healing.

[0024] Dandelion has a bitter and sweet taste, is cold in nature, and enters the liver and stomach meridians. It has the effects of clearing heat and detoxifying, promoting diuresis and resolving lumps, and can be used for acute mastitis, lymphadenitis, scrofula, boils and carbuncles, acute conjunctivitis, fever due to colds, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, and urinary tract infections.

[0025] Aconite root, with a pungent and sweet taste, is hot in nature and toxic. It enters the heart, spleen, and kidney meridians. It has the functions of restoring yang and rescuing from collapse, tonifying fire and assisting yang, dispelling cold and relieving pain. It can be used for yang collapse and reversal, cold limbs and weak pulse, impotence and cold uterus, cold pain in the epigastrium and abdomen, edema due to yin cold, and wind-cold-dampness arthralgia.

[0026] Angelica sinensis, sweet and pungent in taste, warm in nature, and enters the liver, heart, and spleen meridians. It has the functions of nourishing blood, promoting blood circulation, regulating menstruation and relieving pain, and moistening dryness and lubricating the intestines. It can be used to treat various symptoms of blood deficiency, irregular menstruation, amenorrhea, dysmenorrhea, abdominal masses, metrorrhagia, abdominal pain due to deficiency and cold, weakness and numbness, numbness of the skin, constipation due to intestinal dryness, tenesmus after dysentery, carbuncles and sores, and injuries from falls and blows.

[0027] Raw Arisaema has a bitter and pungent taste, is warm in nature, and is toxic. It enters the lung, liver, and spleen meridians. It has the effects of drying dampness and resolving phlegm, dispelling wind and relieving spasms, and dispersing nodules and reducing swelling. It can be used for stubborn cough with phlegm, dizziness due to wind-phlegm, phlegm obstruction due to stroke, facial paralysis, hemiplegia, epilepsy, infantile convulsion, and tetanus. When used externally, it can be used to treat carbuncles and snake and insect bites.

[0028] Frankincense has a pungent and bitter taste, and is warm in nature. It enters the heart, liver, and spleen meridians. It has the effects of regulating qi and blood circulation, relieving pain, and eliminating toxins. It can be used for qi and blood stagnation, abdominal pain, carbuncles and boils, traumatic injuries, dysmenorrhea, and postpartum blood stasis and stabbing pain.

[0029] Corydalis rhizome is warm in nature, pungent and bitter in taste, and enters the liver and spleen meridians. It has the effects of promoting blood circulation, removing blood stasis, regulating qi, and relieving pain. It can be used to treat pain caused by qi stagnation and blood stasis in various parts of the body, dysmenorrhea, amenorrhea, abdominal masses, postpartum blood stasis, traumatic injuries, and hernia pain.

[0030] Peony bark is bitter and pungent in taste, slightly cold in nature, and enters the heart, liver, and kidney meridians. It has the effects of clearing heat and cooling blood, promoting blood circulation and removing blood stasis, and reducing deficiency heat.

[0031] White cardamom has a pungent and warm nature, and enters the lung, spleen, and stomach meridians. It has the functions of resolving dampness, promoting qi circulation, warming the middle jiao, and stopping vomiting. It can be used for symptoms such as dampness obstructing qi, spleen and stomach disharmony, abdominal distension, loss of appetite, early stage of damp-heat syndrome, chest tightness and lack of hunger, cold stomach and vomiting, and food stagnation.

[0032] Fangfeng (Saposhnikovia divaricata) has a pungent and sweet taste and is warm in nature. It has the effects of relieving exterior syndromes and inducing sweating, dispelling wind and dampness, and is mainly used to treat colds caused by wind and cold, headaches, fever, joint pain, and tetanus.

[0033] Among them, dragon's blood, as the principal ingredient, can stop bleeding, promote tissue regeneration, astringe wounds, accelerate wound healing, and reduce purulent secretions; dandelion, as the assistant ingredient, can clear heat and detoxify, and has a significant inhibitory effect on epidermal fungi such as Staphylococcus aureus, thus reducing wound infection. For postpartum women, dandelion is too cold in nature for those with yang deficiency and external cold, while aconite can warm and invigorate yang, dispel cold, and relieve pain. Angelica sinensis, as the adjuvant ingredient, nourishes blood and promotes blood circulation to nourish wound repair and new tissue growth. Damp-heat accumulation and qi deficiency and blood stasis are important reasons for slow wound healing, especially for postpartum women who are more prone to qi and blood stagnation due to qi and blood depletion. Furthermore, the perineal area is more susceptible to external damp-heat toxins in the environment of urine, lochia, and feces. Peony bark clears heat and cools blood, while white cardamom promotes qi circulation and eliminates dampness, enabling the elimination of dampness and clearing of heat toxins. Raw Arisaema heterophyllum has a pungent, warm, and drying nature, which can disperse and invigorate blood. Combined with frankincense to regulate qi and invigorate blood, and Corydalis yanhusuo to regulate qi and dispel blood stasis, the flow of qi leads to the flow of blood, leaving no place for damp-heat to stagnate. Saposhnikovia divaricata, as an adjuvant, guides the medicine to the surface, concentrating the medicinal properties of each herb; furthermore, Aconitum carmichaelii is incompatible with Saposhnikovia divaricata, thus its toxic side effects can be suppressed. The above components work synergistically to regulate qi and blood, clear damp-heat, dispel blood stasis, inhibit wound infection, and accelerate wound healing. Detailed Implementation

[0034] Unless otherwise specified in the embodiments of this invention, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments whose manufacturers are not specified are all commercially available products; different manufacturers and models of raw materials do not affect the implementation of the technical solution or the achievement of the technical effect of this invention.

[0035] Example 1

[0036] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following raw materials in parts by weight:

[0037] 100 parts of dragon's blood, 100 parts of dandelion, 30 parts of aconite, 60 parts of angelica, 20 parts of raw arisaema, 100 parts of frankincense, 50 parts of corydalis, 50 parts of peony bark, 30 parts of white cardamom, and 20 parts of saposhnikovia.

[0038] The preparation method of the traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following steps:

[0039] (1) Take the following ingredients by weight: dragon's blood, dandelion, aconite, angelica, raw arisaema, peony bark, and white cardamom. After crushing them, soak them in 8 times the volume of water at 30°C for 6 hours, then decoct them for 4 hours. Concentrate, dry, and crush the decoction to obtain the first extract.

[0040] (2) Take frankincense, corydalis and saposhnikovia according to the weight parts, crush them, and extract them by reflux with 50% ethanol for 2 hours. Then concentrate, dry and crush the extract to obtain the second extract.

[0041] (3) Mix the first extract and the second extract evenly, and then mix them evenly with petrolatum and polysorbate-80 to obtain the final product.

[0042] The mass ratio of the mixture of the first extract and the second extract to the petrolatum and polysorbate-80 is 10:5:1.

[0043] Example 2

[0044] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following raw materials in parts by weight:

[0045] 200 parts of dragon's blood, 120 parts of dandelion, 50 parts of aconite, 50 parts of angelica, 30 parts of raw arisaema, 80 parts of frankincense, 80 parts of corydalis, 40 parts of peony bark, 20 parts of white cardamom, and 30 parts of saposhnikovia.

[0046] The preparation method of the traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following steps:

[0047] (1) Take the following ingredients by weight: blood dragon, dandelion, aconite, angelica, raw arisaema, peony bark, and white cardamom. After crushing them, use 9 times the volume of water to soak them at 40°C for 12 hours, then decoct them for 3 hours. Decoctions are repeated 3 times. The decoctions are combined, concentrated, dried, and crushed to obtain the first extract.

[0048] (2) Take frankincense, corydalis and saposhnikovia according to the weight parts, crush them, and extract them by reflux with 60% ethanol for 5 times, 1 hour each time. Then concentrate, dry and crush the extract to obtain the second extract.

[0049] (3) Mix the first extract and the second extract evenly, and then mix them evenly with petrolatum and polysorbate-80 to obtain the final product.

[0050] The mass ratio of the mixture of the first extract and the second extract to the petrolatum and polysorbate-80 is 10:8:2.

[0051] Example 3

[0052] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following raw materials in parts by weight:

[0053] 150 parts of dragon's blood, 80 parts of dandelion, 40 parts of aconite, 80 parts of angelica, 40 parts of raw arisaema, 120 parts of frankincense, 70 parts of corydalis, 30 parts of peony bark, 40 parts of white cardamom, and 10 parts of saposhnikovia.

[0054] The preparation method of the traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following steps:

[0055] (1) Take the following ingredients by weight: blood dragon, dandelion, aconite, angelica, raw arisaema, peony bark, and white cardamom. After crushing them, use 10 times the volume of water to soak them at 15°C for 8 hours, then decoct them for 2 hours. Decoction is repeated 5 times. The decoctions are combined, concentrated, dried, and crushed to obtain the first extract.

[0056] (2) Take frankincense, corydalis and saposhnikovia according to the weight parts, crush them, and extract them by reflux with ethanol with a volume concentration of 40% three times, each time for 1.5 hours. Then concentrate, dry and crush the extract to obtain the second extract.

[0057] (3) Mix the first extract and the second extract evenly, and then mix them evenly with petrolatum and polysorbate-80 to obtain the final product.

[0058] The mass ratio of the mixture of the first extract and the second extract to the petrolatum and polysorbate-80 is 10:3:1.

[0059] Example 4

[0060] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following raw materials in parts by weight:

[0061] 180 parts of dragon's blood, 120 parts of dandelion, 40 parts of aconite, 60 parts of angelica, 25 parts of raw arisaema, 80 parts of frankincense, 65 parts of corydalis, 30 parts of peony bark, 30 parts of white cardamom, and 25 parts of saposhnikovia.

[0062] The preparation method of the traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following steps:

[0063] (1) Take the following ingredients by weight: blood dragon, dandelion, aconite, angelica, raw arisaema, peony bark, and white cardamom. After crushing them, soak them in 10 times the volume of water at 25°C for 12 hours, then decoct them for 2 hours. Decoctions are repeated 3 times. The decoctions are combined, concentrated, dried, and crushed to obtain the first extract.

[0064] (2) Take frankincense, corydalis and saposhnikovia according to the weight parts, crush them, and extract them by reflux with 50% ethanol for 2 hours each time. Then concentrate, dry and crush the extract to obtain the second extract.

[0065] (3) Mix the first extract and the second extract evenly, and then mix them evenly with petrolatum and polysorbate-80 to obtain the final product.

[0066] The mass ratio of the mixture of the first extract and the second extract to the petrolatum and polysorbate-80 is 10:4:1.

[0067] Comparative Example 1

[0068] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4 and is prepared using the same method as in Example 4, except that it does not contain Aconitum carmichaelii.

[0069] Comparative Example 2

[0070] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4, and is prepared using the same method as in Example 4, except that the amount of Aconitum carmichaelii is 80 parts.

[0071] Comparative Example 3

[0072] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4 and is prepared using the same method as in Example 4, except that it does not contain Saposhnikovia divaricata.

[0073] Comparative Example 4

[0074] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4 and is prepared using the same method as in Example 4, except that it does not contain peony bark or cardamom.

[0075] Comparative Example 5

[0076] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4, and is prepared using the same method as in Example 4, except that it does not contain raw Arisaema heterophyllum.

[0077] Comparative Example 6

[0078] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment is the same as that in Example 4, and is prepared using the same method as in Example 4, except that the dosage of raw Arisaema is 60 parts.

[0079] Comparative Example 7

[0080] The traditional Chinese medicine composition for promoting perineal wound healing in this embodiment includes the following raw materials in parts by weight: 180 parts of dragon's blood and 120 parts of dandelion.

[0081] The traditional Chinese medicine composition for promoting perineal wound healing described in this embodiment was prepared using the same method as in Example 4.

[0082] Effect Comparison

[0083] To verify the technical efficacy of the traditional Chinese medicine composition for promoting perineal wound healing described in this invention, the following experiments were conducted:

[0084] SD rats weighing 200±20g were randomly divided into 14 groups of 20 rats each, designated as Example 1-4, Comparative Examples 1-7, Blank Group, Model Group, and Control Group. Except for the Blank Group and Control Group, all rats were injected daily with doxorubicin (8mg / kg) for 5 consecutive days to establish a Qi deficiency and blood stasis model. The Blank Group and Control Group were injected with the same volume of physiological saline. On day 6, after anesthetizing the rats with ether, the hair on their backs was removed, and a full-thickness skin excised in a circular pattern with a diameter of 2cm, down to the deep fascia, was created to form a wound.

[0085] After surgery, rats were treated with the traditional Chinese medicine compositions of Examples 1-4 and Comparative Examples 1-7, respectively. The control group received the traditional Chinese medicine composition of Example 4. The compositions were applied every 12 hours. The model group and the blank group were disinfected with 2% iodine tincture every 12 hours. On the 5th day after the operation, the average levels of SOD (superoxide dismutase), MAD (malondialdehyde), TXA2 (thromboxane A2), and PGI2 (prostacyclin) in the plasma of rats in each group were measured.

[0086] In addition, the wound area was recorded on the 3rd, 7th and 14th days after drug administration, and the average wound healing rate of each group of rats was calculated.

[0087] The healing rate is calculated using the following formula: Healing rate = (Initial wound area - Wound area measured on day n) / Initial wound area × 100%.

[0088] The average levels of SOD (superoxide dismutase), MAD (malondialdehyde), TXA2 (thromboxane A2), and PGI2 (prostacyclin) in the plasma of rats in each group were obtained through experiments, and the results are as follows:

[0089]

[0090] The average wound healing rate of each group of rats was as follows:

[0091]

[0092]

[0093] Based on the above results, it can be seen that the traditional Chinese medicine composition for promoting perineal wound healing described in this invention has significant efficacy.

[0094] (1) Data on SOD (superoxide dismutase), MAD (malondialdehyde), TXA2 (thromboxane A2), and PGI2 (prostacyclin) in the plasma of rats in each group showed that, compared with the blank group, the model group had decreased SOD activity and increased MDA content, indicating an imbalance in free radical metabolism and a decreased ability of the body to scavenge free radicals, leading to oxidative damage and manifesting as a state of qi deficiency. Simultaneously, the model group showed increased TXA2 and decreased PGI2, indicating an imbalance between TXA2, which promotes thrombus formation, and PGI2, which inhibits platelet aggregation, in the rats' blood, resulting in impaired vasoconstriction and a predisposition to thrombosis, manifesting as a state of blood stasis.

[0095] In the control group, without the treatment of qi deficiency and blood stasis, the application of the traditional Chinese medicine composition of Example 4 can greatly promote the circulation of qi and blood, improve the body's ability to scavenge free radicals to a certain extent, and better maintain the TXA2-PGI2 balance.

[0096] Compared to Comparative Examples 1-7, the herbal compositions in Examples 1-4 showed varying degrees of improvement in treating Qi deficiency and blood stasis. Specifically, Comparative Examples 1, 2, and 3, compared to Example 4, did not introduce Aconitum carmichaelii to neutralize the cold nature of dandelion, resulting in poor improvement of Qi deficiency and blood stasis. Excessive use of Aconitum carmichaelii could worsen the symptoms. Even without acute poisoning, large doses of Aconitum carmichaelii, due to its hot nature, could damage essence and blood, potentially leading to death or physical deterioration with prolonged use. Therefore, it should be used in moderation, with Angelica sinensis to nourish Yin and blood, combined with Saposhnikovia divaricata to suppress its toxic side effects, in order to tonify Yang, invigorate blood, and dispel blood stasis. Comparative Examples 4 and 7, compared to Example 4, showed that while the principal and assistant herbs had the effect of dispersing blood stasis and lumps, their efficacy was not significant enough. Better efficacy could only be achieved through the combination of the other components. Comparative Examples 5 and 6, compared to Example 4, showed that raw Arisaema heterophyllum had a certain effect on improving the symptoms of Qi deficiency and blood stasis, but its effect was weakened in cases of excessive use.

[0097] (2) The results of the average wound healing rate of rats in each group showed that, compared with the model group, the wound healing time in the blank group was shorter and the healing rate was higher in the same time period, indicating that qi deficiency and blood stasis can have an adverse effect on wound healing. In the control group, without qi deficiency and blood stasis modeling treatment, the application of the traditional Chinese medicine composition of Example 4 resulted in a shorter wound healing time and a higher healing rate in the same time period compared with the blank group. In Example 4, compared with the control group, the average healing rate differed significantly only on the third day; the healing results on the 7th and 14th days were not significantly different.

[0098] Compared to Comparative Examples 1-7, the herbal compositions in Examples 1-4 showed better wound healing. Among them, Example 4 showed the best wound healing.

[0099] As is known from common technical knowledge, this invention can be implemented through other embodiments that do not depart from its spirit or essential characteristics. Therefore, the disclosed embodiments described above are merely illustrative in all respects and are not the only ones. All modifications within the scope of this invention or its equivalents are included in this invention.

Claims

1. A traditional Chinese medicine composition for promoting perineal wound healing, characterized in that, It is made of raw medicinal materials by weight parts as follows: Dracaena 100-200 parts, Herba Taraxaci 80-120 parts, Aconiti Lateralis Preparata 30-50 parts, Angelica 50-80 parts, Rhizoma Smilacis Glabrae 20-40 parts, Olibanum 80-120 parts, Corydalis 50-80 parts, Cortex Moutan 30-50 parts, Amomum 20-40 parts, Saposhnikovia 10-30 parts.

2. The traditional Chinese medicine composition for promoting perineal wound healing according to claim 1, characterized in that, It is made of raw medicinal materials by weight parts as follows: Dracaena 180 parts, Herba Taraxaci 120 parts, Aconiti Lateralis Preparata 40 parts, Angelica 60 parts, Rhizoma Smilacis Glabrae 25 parts, Olibanum 80 parts, Corydalis 65 parts, Cortex Moutan 30 parts, Amomum 30 parts, Saposhnikovia 25 parts.

3. A method of preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 1 or 2, characterized in that, It comprises the following steps: taking Dracaena, Herba Taraxaci, Aconiti Lateralis Preparata, Angelica, Rhizoma Smilacis Glabrae, Olibanum, Corydalis, Cortex Moutan, Amomum, and Saposhnikovia, mixing them uniformly, and preparing into a clinically acceptable preparation.

4. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 3, characterized in that, It comprises the following steps: (1) taking Dracaena, Herba Taraxaci, Aconiti Lateralis Preparata, Angelica, Rhizoma Smilacis Glabrae, Cortex Moutan, and Amomum by weight parts, crushing them, and using water decoction, and then concentrating, drying, and crushing the decoction liquid to obtain a first extract; (2) taking Olibanum, Corydalis, and Saposhnikovia by weight parts, crushing them, and using ethanol reflux extraction, and then concentrating, drying, and crushing the extract liquid to obtain a second extract; (3) mixing the first extract and the second extract uniformly, and then mixing them with vaseline and polysorbate-80 uniformly to obtain the product.

5. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 4, characterized in that, In step (1), 8-10 times of water is used for decoction for 2-4 hours.

6. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 4, characterized in that, In step (1), before water decoction, the raw medicinal materials are soaked for 6-12 hours at a temperature of 15-40℃.

7. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 4, characterized in that, In step (2), the volume concentration of ethanol is 40-60%, and the reflux extraction is performed for 1-2 hours.

8. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 4, characterized in that, In step (1), water decoction is performed for 1-5 times; and in step (2), ethanol reflux extraction is performed for 1-5 times.

9. The method for preparing the traditional Chinese medicine composition for promoting perineal wound healing according to claim 4, characterized in that, In step (3), the mass ratio of the mixture of the first extract and the second extract to the vaseline and the polysorbate-80 is 10:(3-8):(1-2).

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