A soothing repair composition and uses

Abstract

The application discloses a soothing and repairing composition and application, and relates to the cosmetic technical field.The soothing and repairing composition comprises kava root extract, mussel extract, catnip extract and verbena flower extract.The four components have a synergistic effect, can repair the skin barrier, heal the skin structure, reduce the inflammatory reaction, and have a good moisturizing effect.The soothing and repairing composition can instantly soothe the skin allergic reaction and repair the skin barrier, restores the skin to a healthy state, is mild and non-irritating, and has a relatively wide application prospect.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a soothing and repairing composition and its application. Background Technology

[0002] Sensitive skin is a complex process involving the skin barrier, neurovascular system, and immune inflammation. External physical and chemical factors such as UV radiation damage and irritants in cosmetic ingredients, as well as internal factors such as psychological stress, can easily lead to decreased skin immunity, thinning of the stratum corneum, and increased skin sensitivity. This results in symptoms such as burning, itching, and tightness when the skin is irritated, along with characteristics like erythema and exaggerated capillaries.

[0003] Many related technologies achieve soothing and repairing effects by avoiding the addition of irritating ingredients (such as fragrances, pigments, alcohol, and preservatives), or by adding some anti-allergy agents (such as antihistamines). However, these methods do not effectively repair the skin barrier, have limited anti-allergy effects, and can lead to dependence with long-term use. Therefore, there is a need for a composition that can soothe and repair sensitive skin. Summary of the Invention

[0004] The present invention aims to at least solve one of the technical problems existing in the prior art. To this end, the present invention proposes a soothing and repairing composition that is gentle and non-irritating, and has excellent moisturizing and soothing and repairing effects.

[0005] The present invention also provides the use of the above-described soothing and repairing composition in the preparation of cosmetics.

[0006] The present invention also provides cosmetics comprising the above-described soothing and repairing composition.

[0007] A soothing and repairing composition according to a first aspect of the present invention comprises: kava root extract, mussel extract, catnip extract, and senna flower extract.

[0008] The soothing and repairing composition according to embodiments of the present invention has at least the following beneficial effects:

[0009] The synergistic effect of kava root extract, mussel extract, catnip extract, and senna flower extract in this embodiment can repair the skin barrier, heal skin structure, reduce inflammation, and also has a good moisturizing effect. It can immediately soothe skin allergies and repair the skin barrier, restoring the skin to a healthy state. It is gentle and non-irritating, and has broad application prospects.

[0010] According to some embodiments of the present invention, the ingredients, by weight, include: 0.5 to 5 parts of kava root extract, 0.001 to 10 parts of mussel extract, 0.01 to 8 parts of catnip extract, and 0.01 to 4 parts of senna flower extract.

[0011] According to some embodiments of the present invention, the ingredients, by weight, include: 0.1 to 1 part of kava root extract, 0.01 to 3 parts of mussel extract, 0.1 to 1.5 parts of catnip extract, and 0.1 to 0.5 parts of senna flower extract.

[0012] According to some embodiments of the present invention, the ingredients, by weight, include: 0.5 to 1 part of kava root extract, 1 to 3 parts of mussel extract, 0.5 to 1.5 parts of catnip extract, and 0.3 to 0.5 parts of senna flower extract.

[0013] According to some embodiments of the present invention, the ingredients, by weight, include: 0.8-1 parts of kava root extract, 1-3 parts of mussel extract, 1-1.5 parts of catnip extract, and 0.4-0.5 parts of senna flower extract.

[0014] The application of the above-described soothing and repairing composition according to a second aspect of the present invention in the preparation of cosmetics.

[0015] According to some embodiments of the present invention, the cosmetic is a facial cleanser, toner, serum, lotion, cream, mask, or foundation.

[0016] A cosmetic product according to a third aspect of the present invention comprises the soothing and repairing composition as described in the first aspect of the present invention. Since the cosmetic product employs all the technical solutions of the soothing and repairing composition of the above embodiments, it possesses at least all the beneficial effects brought about by the technical solutions of the above embodiments.

[0017] According to some embodiments of the present invention, the soothing and repairing composition comprises 1 wt% to 10 wt% of the total mass of the cosmetic product. For example, it may be 1 wt%, 2 wt%, 3 wt%, 4 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt%, or 10 wt%.

[0018] According to some embodiments of the present invention, the excipients comprise at least one of antioxidants, solubilizers, fragrances, pH adjusters, emollients, emulsifiers, thickeners, humectants, skin protectants, and preservatives.

[0019] According to some embodiments of the present invention, the pH adjuster includes at least one selected from aminomethylpropanol, triethanolamine, arginine, citric acid, and sodium citrate. For example, when the pH adjuster includes aminomethylpropanol, it may specifically include AMP-ULTRA PC 2000.

[0020] According to some embodiments of the present invention, the thickener includes at least one of hydroxyethyl cellulose, xanthan gum, carbomer, acrylate / C10-30 alkanol acrylate crosspolymer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyl taurate / VP copolymer, and glyceryl polyacrylate.

[0021] According to some embodiments of the present invention, the emulsifier includes at least one selected from Lysofix Liquid (including glycerol and wild soybean seed extract), glyceryl stearate, PEG-100 stearate, methyl glucosesquistearate, polysorbate-20, PEG-20 glyceryl triisostearate, PEG-80 hydrogenated castor oil, PEG-7 glyceryl cocoate, C14-22 alcohol, cetearyl alcohol, cetearyl oleate, sorbitan oleate, C12-20 alkyl glucoside, cetearyl glucoside, glyceryl tri(ethylhexanoate), and arachidonic acid glucoside.

[0022] According to some embodiments of the present invention, the moisturizer includes at least one of glycerin, sodium hyaluronate, squalane, olive fruit oil, jojoba seed oil, 1,2-pentanediol, butylene glycol, 1,3-propylene glycol, ethoxydiethylene glycol, sorbitol, and dipropylene glycol.

[0023] Other features and advantages of the invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. Detailed Implementation

[0024] The following will describe the concept and technical effects of the present invention clearly and completely with reference to embodiments, so as to fully understand the purpose, features and effects of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are all within the scope of protection of the present invention.

[0025] Unless otherwise specified in the examples, the procedures should be performed under standard conditions or conditions recommended by the manufacturer. Reagents or instruments whose manufacturers are not specified are all commercially available products.

[0026] In the description of this invention, the terms “comprising” and “having”, and any variations thereof, are intended to cover non-exclusive inclusion, for example, a process, method, system, product, or device that includes a series of steps or units is not necessarily limited to those steps or units that are explicitly listed, but may include other steps or units that are not explicitly listed or that are inherent to such process, method, product, or device.

[0027] When a numerical range is disclosed herein, the range is considered continuous and includes the minimum and maximum values ​​of the range, as well as every value between the minimum and maximum values. Furthermore, when the range refers to integers, it includes every integer between the minimum and maximum values ​​of the range. Additionally, when multiple ranges are provided to describe a feature or characteristic, the ranges may be combined. In other words, unless otherwise specified, all ranges disclosed herein should be understood to include any and all subranges to which they are incorporated.

[0028] The kava (PIPER METHYSTICUM) root extract involved in this embodiment of the invention was purchased from Oxylux, trade name: Kava Extract UP;

[0029] Mussel extract: purchased from Sinopharm (Guangzhou) International Pharmaceutical and Health Co., Ltd., trade name: Mussel extract;

[0030] Nepeta cataria extract: purchased from Sinopharm (Guangzhou) International Pharmaceutical and Health Co., Ltd., trade name: Nepeta cataria extract;

[0031] Jasminum officinale flower extract: purchased from Guangzhou Nuowei Biotechnology Co., Ltd., trade name: Jasminum officinale flower extract.

[0032] Example 1

[0033] This example provides a soothing and repairing composition, which, by weight, consists of 0.5 parts of kava pepper root extract, 1 part of mussel extract, 0.5 parts of catnip extract, and 0.3 parts of senna flower extract.

[0034] Example 2

[0035] This example provides a soothing and repairing composition, which, by weight, consists of 0.1 parts of kava pepper root extract, 0.01 parts of mussel extract, 0.1 parts of catnip extract, and 0.1 parts of senna flower extract.

[0036] Example 3

[0037] This example provides a soothing and repairing composition, which, by weight, consists of 1 part kava pepper root extract, 3 parts mussel extract, 1.5 parts catnip extract, and 0.5 parts senna flower extract.

[0038] Example 4

[0039] This example provides a soothing and repairing composition, which, by weight, consists of 0.8 parts of kava pepper root extract, 1 part of mussel extract, 1 part of catnip extract, and 0.4 parts of senna flower extract.

[0040] Example 5

[0041] This example provides a soothing and repairing composition, which, by weight, consists of 0.5 parts of kava root extract, 2 parts of mussel extract, 0.5 parts of catnip extract, and 0.3 parts of senna flower extract.

[0042] Comparative Example 1

[0043] This example provides a soothing and repairing composition, which is basically the same as the formulation in Example 1, except that kava pepper root extract is omitted.

[0044] Comparative Example 2

[0045] This example provides a soothing and repairing composition, which is basically the same as the formulation in Example 1, except that mussel extract is omitted.

[0046] Comparative Example 3

[0047] This example provides a soothing and repairing composition, which is basically the same as the formulation in Example 1, except that the catnip extract is omitted.

[0048] Comparative Example 4

[0049] This example provides a soothing and repairing composition, which is basically the same as the formulation in Example 1, except that the extract of Sufanghua flower is omitted.

[0050] Comparative Example 5

[0051] This example provides a soothing and repairing composition containing only 0.5 parts by weight of kava pepper root extract.

[0052] Comparative Example 6

[0053] This example provides a soothing and repairing composition containing only 1 part by weight of mussel extract.

[0054] Comparative Example 7

[0055] This example provides a soothing and repairing composition containing only 0.5 parts by weight of catnip extract.

[0056] Comparative Example 8

[0057] This example provides a soothing and repairing composition containing only 0.3 parts by weight of Succulenta flower extract.

[0058] Comparative Example 9

[0059] This example provides a soothing and repairing composition, which is basically the same as the formulation in Example 1, except that the catnip extract and senna flower extract are omitted.

[0060] Application Examples

[0061] This application example provides five serums, with formulas shown in Table 1. The content of each component is expressed as a weight percentage.

[0062] Table 1

[0063]

[0064] The preparation methods of the serums used in Examples 1-5 are as follows:

[0065] (1) Deionized water, glycerin, sodium hyaluronate and acrylate / C10-30 alkanol acrylate crosspolymer were stirred and dissolved in a weight ratio, heated to 80℃~85℃ and kept warm for 10 min~15 min to obtain phase A; squalane, jojoba seed oil, olive fruit oil and Lysofix Liquid (glycerin and wild soybean seed extract) were stirred and dissolved in a weight ratio at 75℃~80℃ to obtain phase B; 1,2-pentanediol and p-hydroxyacetophenone were mixed and dissolved at 55℃~60℃ to obtain phase C;

[0066] (2) Add phase B to phase A, stir evenly, homogenize, and keep warm for 5-10 minutes; after cooling to 55℃~60℃, add phase C and AMP-ULTRA PC 2000, stir evenly, and homogenize.

[0067] (4) After the temperature drops to below 45°C, add kava root extract, mussel extract, catnip extract and succulent flower extract according to the weight ratio, and continue stirring until the temperature drops to below 38°C to obtain the essence.

[0068] Application of comparative examples

[0069] This application example provides 10 serum formulations, as shown in Table 2. The preparation method is the same as in application example 1.

[0070] Table 2

[0071]

[0072] Detection Example 1

[0073] This test example uses patch experiments on the serums from Application Examples 1-5 and Comparative Examples 1-10 to test their irritation.

[0074] A total of 480 volunteers were recruited and randomly divided into 16 groups of 30 each. Among them, 15 groups of volunteers tested the serums of Examples 1-5 and Comparative Examples 1-10, respectively, while the volunteers in the blank control group did not use any products.

[0075] Using a syringe, 0.03 mL of test sample was placed in the drug chamber of the test strip. Immediately, the test strip containing the sample was applied longitudinally to the normal skin of the volunteer's left forearm, starting from the bottom. Simultaneously, each chamber was gently pressed to expel air and ensure even distribution of the test sample. The test sites were marked for observation. The test strip was removed after 24 hours. Skin reactions were observed at 0.5 hours, 24 hours, and 48 hours, and the results were recorded and analyzed according to the CTFA guidelines. The criteria for identifying skin irritation are shown in Table 3.

[0076] Table 3

[0077]

[0078] The test results are shown in Table 4.

[0079] Table 4

[0080]

[0081] No adverse reactions were observed in volunteers who used the serums from Examples 1-5 and Comparative Examples 1-10. This indicates that the serums from Examples 1-5 and Comparative Examples 1-10 are relatively mild and have good safety.

[0082] Test Example 2

[0083] This test example examines the soothing and repairing efficacy of the serums used in Examples 1-5 and Comparative Examples 1-10.

[0084] A total of 150 volunteers with sensitive skin, aged 18 to 45 years, were recruited. The trial was designed as a randomized, double-blind, historically controlled study. Volunteers were randomly divided into 15 groups of 10 each, and tested with the serums from Examples 1-5 and Comparative Examples 1-10, respectively. Volunteers used the serum twice daily, morning and evening, for 14 consecutive days. On day 0, day 7 (D7), and day 14 (D14), under conditions of 21±1℃ and 50±10% humidity, 20 minutes after facial cleansing, facial hydration and transepidermal water loss (TEWL) were measured. The average redness level of the skin at the test sites was measured using Anthrne 3D photography.

[0085] (1) Moisture content test.

[0086] A higher water content indicates more moisture in the stratum corneum of the test area; a lower water content indicates less moisture in the stratum corneum of the test area.

[0087] Moisture content change rate: This refers to the rate of change in skin moisture content before and after using the product. A positive value indicates an increase in moisture content and improved skin hydration; a negative value indicates a decrease in moisture content and reduced skin hydration.

[0088] The test results are shown in Table 5.

[0089] Table 5

[0090]

[0091] The soothing and repairing compositions in Examples 1-5 all effectively enhance the moisture content of the facial stratum corneum. The absence of any one of the following: kava root extract, mussel extract, catnip extract, or senna flower extract significantly reduces the effectiveness.

[0092] (2) TEWL value test.

[0093] A higher TEWL value indicates a greater amount of transepidermal water loss per unit time and per unit cross-sectional area; a lower TEWL value indicates a less amount of transepidermal water loss per unit time and per unit cross-sectional area.

[0094] TEWL value change rate: This refers to the rate of change in the rate of skin moisture loss before and after product use. A negative value indicates a decreased rate of skin moisture loss and enhanced skin barrier function; a positive value indicates an increased rate of skin moisture loss and weakened skin barrier function.

[0095] The test results are shown in Table 6.

[0096] Table 6

[0097]

[0098] The soothing and repairing compositions in Examples 1-5 all have excellent moisturizing effects, effectively reducing skin moisture loss and repairing the skin barrier. The absence of any one of the following ingredients—kava root extract, mussel extract, catnip extract, or senna flower extract—significantly reduces the effectiveness.

[0099] (3) Relief test.

[0100] The higher the average reddish hue, the larger the red area (or the greater the redness) in the selected region. The lower the average reddish hue, the smaller the red area in the selected region.

[0101] Redness average change rate: This refers to the rate of change in the average redness level before and after using the product. A positive value indicates that the larger the red area (or the greater the redness) in the selected area, the less obvious the effect of relieving skin redness; a negative value indicates that the smaller the red area (or the less redness) in the selected area, the more obvious the effect of relieving skin redness.

[0102] The test results are shown in Table 7.

[0103] Table 7

[0104]

[0105] The soothing and repairing compositions in Examples 1-5 all have excellent soothing and repairing effects, effectively reducing skin redness. The absence of any one of the following ingredients—kava root extract, mussel extract, catnip extract, or senna flower extract—significantly reduces the effectiveness.

[0106] In summary, the root extract of kava pepper, mussel extract, catnip extract, and senna flower extract have a good synergistic effect in moisturizing, soothing and repairing.

[0107] The embodiments of the present invention have been described in detail above with reference to the examples. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A soothing and repairing composition, characterized in that, By weight, it includes: 0.1 to 1 part of kava root extract, 0.01 to 3 parts of mussel extract, 0.1 to 1.5 parts of catnip extract, and 0.1 to 0.5 parts of senna flower extract.

2. The soothing and repairing composition according to claim 1, characterized in that, By weight, it includes: 0.5-1 part of kava root extract, 1-3 parts of mussel extract, 0.5-1.5 parts of catnip extract, and 0.3-0.5 parts of senna flower extract.

3. The soothing and repairing composition according to claim 2, characterized in that, By weight, it includes: 0.8-1 part of kava root extract, 1-3 parts of mussel extract, 1-1.5 parts of catnip extract, and 0.4-0.5 parts of senna flower extract.

4. The use of the soothing and repairing composition according to any one of claims 1 to 3 in the preparation of cosmetics.

5. The application according to claim 4, characterized in that, The cosmetics mentioned are toners, serums, lotions, creams, masks, or foundations.

6. A cosmetic product, characterized in that, The cosmetic product comprises the soothing and repairing composition according to any one of claims 1 to 3 and cosmetically acceptable excipients.

7. The cosmetic product according to claim 6, characterized in that, The soothing and repairing composition comprises 1 wt% to 10 wt% of the total mass of the cosmetic product.

8. The cosmetic product according to claim 6, characterized in that, The excipients include at least one of antioxidants, solubilizers, fragrances, pH adjusters, emollients, emulsifiers, thickeners, humectants, skin protectants, and preservatives.

Images