A traditional Chinese medicine composition and traditional Chinese medicine preparation for treating subacute thyroiditis

Abstract

The present application belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating subacute thyroiditis, which comprises the following traditional Chinese medicine raw materials in a mass ratio: Bupleurum 9-12 parts; Red Peony Root 10-15 parts; Indigowood Leaf 10-15 parts; Scrophularia 9-12 parts; Glechoma 10-15 parts; Limnophila 15-30 parts; Millettia 3-6 parts; Omphalopsis 6-9 parts; and Aquilaria 10-15 parts. The present application also provides a traditional Chinese medicine preparation for treating subacute thyroiditis: the above traditional Chinese medicine raw materials are taken according to the ratio, and a pharmaceutically acceptable carrier is added to form a traditional Chinese medicine preparation, wherein the traditional Chinese medicine preparation comprises an ointment and an external use patch. The traditional Chinese medicine composition and the traditional Chinese medicine preparation for treating subacute thyroiditis have the advantages of being simple and easy to use, rapid in effect, and green and safe.

Description

Technical Field

[0001] This invention belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition and preparation for treating subacute thyroiditis. Background Technology

[0002] Subacute thyroiditis is a common endocrine disorder, generally believed to be related to viral infection, with patients often developing symptoms 1-3 weeks after viral infection. Treatment mainly focuses on two aspects: relieving symptoms and correcting thyroid dysfunction. Currently, the mainstream treatment drugs are nonsteroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids. For patients with mild symptoms, oral NSAIDs (such as indomethacin and celecoxib) alone can relieve symptoms, generally requiring about 2 weeks of treatment. For patients with severe systemic symptoms, persistent high fever, and significant pain, glucocorticoids may be used as appropriate, with prednisone as the first choice, maintained for 1-2 weeks before gradually tapering off. Medication can be discontinued only after ESR returns to normal, with a total treatment course of 1-2 months. However, the safety and effectiveness of these treatment methods are difficult to guarantee.

[0003] To improve the safety and effectiveness of treatment, some traditional Chinese medicine preparations are also used to treat subacute thyroiditis. For example, Chinese invention patent CN102688387A (publication date 2012-09-26) discloses a drug for treating subacute thyroiditis, made from the following Chinese medicinal materials in the following weight ranges: burdock fruit 12-18g, bezoar 0.15-0.25g, andrographis paniculata 18-22g, gardenia 12-18g, tsao-ko 6-8g, belamcanda chinensis 8-12g, seaweed 12-18g, scrophularia ningpoensis 18-22g, schizonepeta tenuifolia 12-18g, peppermint 8-12g, forsythia suspensa 18-22g, safflower 8-12g, notoginseng 8-12g, dendrobium nobile 12-18g, polygala tenuifolia 8-12g, platycodon grandiflorus 8-12g, bupleurum chinense 12-18g, angelica sinensis 12-18g, red peony root 8-12g, rehmannia glutinosa 8-12g, and licorice root 12-18g. The above-mentioned combination of traditional Chinese medicine ingredients has the effects of clearing heat and detoxifying, promoting blood circulation and regulating menstruation, dispersing blood stasis, relieving pain and reducing swelling, and has a significant effect on the treatment of subacute thyroiditis. Furthermore, the above-mentioned traditional Chinese medicine ingredients can be formulated into tablets, powders, capsules, and granules, primarily for oral administration.

[0004] To improve patient compliance, clinical studies on the use of traditional Chinese medicine (TCM) external application for the treatment of subacute thyroiditis have been conducted in recent years. For example, Chinese invention patent CN113244319A (publication date: 2021-08-13) discloses a TCM composition for treating subacute thyroiditis, a TCM patch for subacute thyroiditis, and its preparation method. The TCM composition includes the following raw materials in parts by weight: Polygonum cuspidatum 5-20 parts, Scutellaria barbata 7-30 parts, Scutellaria baicalensis 5-20 parts, Taraxacum mongolicum 7-30 parts, Viola yedoensis 7-30 parts, processed frankincense 3-12 parts, processed myrrh 3-12 parts, and rhubarb 1-6 parts. The preparation method is as follows: weigh the raw materials according to their parts by weight, grind them in a mortar, mix the resulting powdered medicinal materials with 2-8 parts by weight of golden ointment, stir evenly to form a paste, and then evenly apply the paste to a medicated plaster to obtain the TCM patch for subacute thyroiditis.

[0005] External application of traditional Chinese medicine (TCM) preparations are characterized by being simple, convenient, inexpensive, and effective, with no obvious toxic side effects, making them easily accepted by patients and resulting in good compliance. Therefore, external TCM treatments demonstrate certain efficacy and advantages in the treatment of subacute thyroiditis. To further expand the use of external TCM treatments and adapt to individual patient differences, it is essential to research different formulations of TCM preparations. Summary of the Invention

[0006] This invention addresses the shortcomings of existing technologies by providing a traditional Chinese medicine composition and preparation for treating subacute thyroiditis, which has the advantages of being simple and easy to use, having a rapid onset of action, and being green and safe.

[0007] To solve the above-mentioned technical problems, the objective of this invention is achieved through the following technical solution:

[0008] A traditional Chinese medicine composition for treating subacute thyroiditis, the composition comprising the following raw materials in the indicated mass ratios:

[0009] Bupleurum chinense 9-12 parts;

[0010] 10-15 parts of red peony root;

[0011] 10-15 parts of Isatis indigotica leaves;

[0012] 9-12 parts of Scrophularia ningpoensis;

[0013] 10-15 portions of Dryopteris crassirhizoma;

[0014] 15-30 parts of Hedyotis diffusa;

[0015] 3-6 parts of Sophora tonkinensis;

[0016] 6-9 servings of Pseudobulbus Cremastrae;

[0017] 10-15 parts of water safflower seeds.

[0018] The present invention also provides a traditional Chinese medicine preparation for treating subacute thyroiditis: the above-mentioned traditional Chinese medicine raw materials are taken according to the formula and combined with a pharmaceutically acceptable carrier to form a traditional Chinese medicine preparation.

[0019] In the aforementioned traditional Chinese medicine preparation for treating subacute thyroiditis, the preparation is an ointment.

[0020] In the above-mentioned traditional Chinese medicine preparation for treating subacute thyroiditis, the ointment is prepared by the following method: weigh out the raw materials of traditional Chinese medicine according to the proportions, dry them at low temperature and grind them into powder, pass them through a 100-mesh sieve, add the mixed matrix, heat and melt them and stir evenly, cool them down and pass them through an 80-mesh sieve and filter them again, and then place them in a container to solidify naturally to make an ointment, which is then packaged for later use.

[0021] In the aforementioned traditional Chinese medicine preparation for treating subacute thyroiditis, the mixed matrix is ​​a mixture of white petrolatum, azone, glycerin, and lanolin, and the components by mass are as follows:

[0022] 10 servings of white petroleum jelly;

[0023] One part of azone;

[0024] 1 part glycerin;

[0025] 10 parts lanolin.

[0026] In the aforementioned traditional Chinese medicine preparation for treating subacute thyroiditis, the heating and melting temperature is 70°C, and the cooling and sieving temperature is 30°C.

[0027] In the aforementioned traditional Chinese medicine preparation for treating subacute thyroiditis, the volume ratio of the medicinal powder to the mixed matrix is ​​1:1.

[0028] In the above-mentioned traditional Chinese medicine preparation for treating subacute thyroiditis, the traditional Chinese medicine preparation is a compound external patch. The compound traditional Chinese medicine is pulverized into fine powder, mixed with appropriate excipients, and then made into an external patch. It is administered through the skin surface, so that the traditional Chinese medicine ingredients pass through the skin layers at a constant rate and enter the systemic circulation to produce a local therapeutic effect.

[0029] In one of the above-mentioned traditional Chinese medicine preparations for treating subacute thyroiditis, the above-mentioned ointment can be used to further prepare a topical patch: take any of the above-mentioned ointments and spread them on non-woven fabric to form a topical patch.

[0030] This formula uses Bupleurum and Red Peony as the principal herbs. Red Peony has the effects of clearing heat and cooling blood, dispersing blood stasis and relieving pain. Modern pharmacological studies have confirmed that it has the effects of promoting blood circulation, removing blood stasis, and anti-inflammation. Its main component, paeoniflorin, has analgesic and antispasmodic effects. Bupleurum has the effects of purging heat from the exterior and soothing the liver and relieving depression. Modern pharmacological studies have confirmed that it has anti-inflammatory, antiviral, antipyretic, analgesic, immune-regulating, and mood-regulating effects. The combination of the two promotes qi and blood circulation, which can enhance the improvement of neck swelling and pain in patients with subacute thyroiditis. This formula uses Isatis leaf, Sophora root, Dryopteris crassirhizoma, Hedyotis diffusa, and Cremastra appendiculata as the assistant herbs. These five herbs all have the effects of clearing heat and detoxifying. They assist the principal herbs Bupleurum and Red Peony in clearing heat, cooling blood, and detoxifying, so that the internal heat toxins can be eliminated. Isatis leaf has the effects of clearing heat, detoxifying, and cooling blood. Modern pharmacological studies have confirmed that it has antibacterial, antiviral, and immune-enhancing effects. Sophora tonkinensis has the effects of clearing heat, detoxifying, and reducing swelling. Modern pharmacological research shows that it also has anti-inflammatory and immune-boosting effects. The combination of Isatis indigotica leaf and Sophora tonkinensis can enhance the effects of clearing heat, detoxifying, reducing swelling, and relieving pain. Dryopteris crassirhizoma has the effects of clearing heat, detoxifying, cooling blood, and stopping bleeding. Externally, it has analgesic and anti-inflammatory effects. Modern pharmacological research shows that it also has antibacterial and antiviral effects. Hedyotis diffusa has the effects of clearing heat, detoxifying, reducing swelling, and relieving pain. Modern pharmacological research shows that it also has antibacterial, anti-inflammatory, and antioxidant effects. Cremastra appendiculata has the effects of clearing heat, detoxifying, resolving phlegm, and dissipating nodules. Modern pharmacological research shows that it also has antioxidant, antibacterial, anti-inflammatory, and immune-enhancing effects. This formula uses Scrophularia ningpoensis and Polygonum hydropiper as adjuvant herbs, both of which have the effects of dissipating nodules and reducing swelling. It can not only eliminate stagnation of qi, blood, and blood in the neck, but also relieve neck pain. Scrophularia has the effects of nourishing yin and reducing fire, eliminating goiter and dissipating nodules. It is often used for blood heat syndrome in the nutritive level. Modern pharmacological research shows that it has anti-inflammatory, analgesic, and immunomodulatory effects. Polygonum hydropiper has the effects of dispersing blood stasis and eliminating masses, relieving pain. Modern pharmacological research shows that it has antioxidant and immunomodulatory effects.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] 1. This invention provides a novel traditional Chinese medicine composition for treating subacute thyroiditis, targeting the etiology and pathogenesis of the disease. It conforms to the principle of "principal, assistant, adjuvant, and guide" in traditional Chinese medicine formulation. Bupleurum and Paeonia lactiflora are the principal herbs, Isatis tinctoria leaf, Sophora tonkinensis root, Dryopteris crassirhizoma, Hedyotis diffusa, and Cremastra appendiculata are the assistant herbs, and Scrophularia ningpoensis and Polygonum hydropiper are the adjuvant herbs. The combination of these herbs can exert a synergistic therapeutic effect. The components of the traditional Chinese medicine raw materials have mutually reinforcing, promoting, and coordinating effects, resulting in a significant therapeutic effect on subacute thyroiditis.

[0033] 2. This invention further provides a traditional Chinese medicine preparation for treating subacute thyroiditis. It employs external application therapy, based on traditional Chinese medicine theory, combining holistic and local diagnosis. The medicine is applied to corresponding areas or acupoints on the body surface. Through skin penetration and absorption, and the stimulation of the skin and acupoints by the medicine, it regulates the body's Qi, blood, body fluids, meridians, and internal organs, achieving the therapeutic purpose. This therapy allows the medicine to act directly on the affected area, increasing the local drug concentration. Transdermal absorption reduces gastrointestinal irritation, effectively avoiding gastrointestinal discomfort and toxic side effects associated with oral medication. It is simple, easy to administer, rapidly effective, and safe. Detailed Implementation

[0034] The present invention will be further described below through specific embodiments, but this is not a limitation of the present invention. Those skilled in the art can make various modifications or improvements based on the basic idea of ​​the present invention, but as long as they do not depart from the basic idea of ​​the present invention, they are all within the scope of the present invention.

[0035] All raw materials used in this invention can be purchased from ordinary pharmacies or Chinese herbal medicine sales companies, and their specifications comply with national pharmaceutical standards or relevant regulations such as the Chinese Pharmacopoeia. Unless otherwise specified, all medicinal materials used are processed Chinese herbal medicine slices, which may also be obtained and then processed.

[0036] Example 1

[0037] Traditional Chinese medicine preparation for treating subacute thyroiditis (1#)

[0038] Dosage of raw materials: Bupleurum chinense 9g, Paeonia lactiflora 15g, Isatis indigotica 15g, Scrophularia ningpoensis 9g, Dryopteris crassirhizoma 10g, Hedyotis diffusa 15g, Sophora tonkinensis 3g, Cremastra appendiculata 9g, Polygonum hydropiper 10g.

[0039] After washing and drying the above-mentioned drugs, weigh out the required amount for each ingredient, dry them at low temperature, grind them into powder, and pass them through a 100-mesh sieve. Add the resulting powder to a mixed matrix (100g white petrolatum, 10g azone, 10g glycerin, and 100g lanolin) in a 1:1 volume ratio. Heat to 70℃ to melt the powder, stir well, and then cool to 30℃. Pass the powder through an 80-mesh sieve and filter it again. Place the mixture in a container and allow it to solidify naturally to make "methylene blue ointment," which is then packaged for later use. When using, apply the ointment to medical gauze, place it on the painful area, and secure it with a medical bandage to provide additional pressure. Apply twice a day for 15 minutes each time.

[0040] Example 2

[0041] Traditional Chinese medicine preparation for treating subacute thyroiditis (2#)

[0042] Dosage of raw materials: Bupleurum chinense 9g, Paeonia lactiflora 12g, Isatis indigotica 15g, Scrophularia ningpoensis 9g, Dryopteris crassirhizoma 10g, Hedyotis diffusa 15g, Sophora tonkinensis 3g, Cremastra appendiculata 6g, Polygonum hydropiper 10g.

[0043] After washing and drying the above-mentioned drugs, weigh out the required amount for each ingredient, dry them at low temperature, grind them into powder, and pass them through a 100-mesh sieve. Add the resulting powder to a mixed matrix (100g white petrolatum, 10g azone, 10g glycerin, and 100g lanolin) in a 1:1 volume ratio. Heat to 70℃ to melt the powder, stir well, and then cool to 30℃. Pass the powder through an 80-mesh sieve and filter it again. Place the mixture in a container and allow it to solidify naturally to make "methylene blue ointment," which is then packaged for later use. When using, apply the ointment to medical gauze, place it on the painful area, and secure it with a medical bandage to provide additional pressure. Apply twice a day for 15 minutes each time.

[0044] Example 3

[0045] Traditional Chinese medicine preparations for treating subacute thyroiditis (3#)

[0046] Dosage of raw materials: Bupleurum chinense 9g, Paeonia lactiflora 15g, Isatis indigotica 15g, Scrophularia ningpoensis 9g, Dryopteris crassirhizoma 15g, Hedyotis diffusa 20g, Sophora tonkinensis 6g, Cremastra appendiculata 6g, Polygonum hydropiper 10g.

[0047] After washing and drying the above-mentioned drugs, weigh out the required amount for each ingredient, dry them at low temperature, grind them into powder, and pass them through a 100-mesh sieve. Add the resulting powder to a mixed matrix (100g white petrolatum, 10g azone, 10g glycerin, and 100g lanolin) in a 1:1 volume ratio. Heat to 70℃ to melt the powder, stir well, and then cool to 30℃. Pass the powder through an 80-mesh sieve and filter it again. Place the mixture in a container and allow it to solidify naturally to make "methylene blue ointment," which is then packaged for later use. When using, apply the ointment to medical gauze, place it on the painful area, and secure it with a medical bandage to provide additional pressure. Apply twice a day for 15 minutes each time.

[0048] Example 4

[0049] Traditional Chinese medicine preparations for treating subacute thyroiditis (4#)

[0050] Dosage of raw materials: Bupleurum chinense 12g, Paeonia lactiflora 15g, Isatis indigotica 15g, Scrophularia ningpoensis 9g, Dryopteris crassirhizoma 15g, Hedyotis diffusa 15g, Sophora tonkinensis 3g, Cremastra appendiculata 9g, Polygonum hydropiper 15g.

[0051] After washing and drying the above-mentioned drugs, weigh out the required amount for each ingredient, dry them at low temperature, grind them into powder, and pass them through a 100-mesh sieve. Add the resulting powder to a mixed matrix (100g white petrolatum, 10g azone, 10g glycerin, and 100g lanolin) in a 1:1 volume ratio. Heat to 70℃ to melt the powder, stir well, and then cool to 30℃. Pass the powder through an 80-mesh sieve and filter it again. Place the mixture in a container and allow it to solidify naturally to make "methylene blue ointment," which is then packaged for later use. When using, apply the ointment to medical gauze, place it on the painful area, and secure it with a medical bandage to provide additional pressure. Apply twice a day for 15 minutes each time.

[0052] Example 5

[0053] Traditional Chinese medicine preparations for treating subacute thyroiditis (5#)

[0054] Dosage of raw materials: Bupleurum chinense 12g, Paeonia lactiflora 15g, Isatis indigotica 15g, Scrophularia ningpoensis 9g, Dryopteris crassirhizoma 15g, Hedyotis diffusa 30g, Sophora tonkinensis 3g, Cremastra appendiculata 6g, Polygonum hydropiper 12g.

[0055] After washing and drying the above-mentioned drugs, weigh out the required amount for each ingredient, dry them at low temperature, grind them into powder, and pass them through a 100-mesh sieve. Add the resulting powder to a mixed matrix (100g white petrolatum, 10g azone, 10g glycerin, and 100g lanolin) in a 1:1 volume ratio. Heat to 70℃ to melt the powder, stir well, and then cool to 30℃. Pass the powder through an 80-mesh sieve and filter it again. Place the mixture in a container and allow it to solidify naturally to make "methylene blue ointment," which is then packaged for later use. When using, apply the ointment to medical gauze, place it on the painful area, and secure it with a medical bandage to provide additional pressure. Apply twice a day for 15 minutes each time.

[0056] Example 6

[0057] Case 1: This case involved the use of the traditional Chinese medicine preparation (1#) prepared in Example 1 for treating subacute thyroiditis.

[0058] Ms. Yuan, 36 years old, presented with subacute thyroiditis for one week. One week prior, she developed bilateral anterior neck pain without any obvious cause, which worsened with swallowing. Masses were palpable in both anterior thyroid regions of the neck. She had no fever, palpitations, or hand tremors. She had taken oral nonsteroidal anti-inflammatory drugs (NSAIDs) for five days, but her symptoms did not improve significantly. She was admitted to our department and given topical application of "Methylene Thyroid Ointment," applied twice daily for 15 minutes each time, for seven consecutive days. She reported some reduction in anterior neck pain and a slight reduction in the size of the thyroid masses. The thyroid glands remained firm. She continued application for another 14 days, resulting in further improvement in her symptoms. The anterior neck pain was essentially relieved, the thyroid masses shrank further, and the thyroid glands softened.

[0059] Example 7

[0060] Case 2: This case involved the use of the traditional Chinese medicine preparation (2#) prepared in Example 2 for the treatment of subacute thyroiditis.

[0061] Mr. Yan, male, 52 years old, had been suffering from subacute thyroiditis for over a month. Over a month prior, he developed mild, dull pain in the left side of his neck without any obvious cause. He self-medicated with Qingkailing, which provided some relief, but did not completely alleviate the symptoms, which he reported as tolerable. One week ago, the symptoms worsened. He did not experience fever, palpitations, or hand tremors. He had been taking nonsteroidal anti-inflammatory drugs (NSAIDs) orally for 7 days, with slight improvement in symptoms. He was admitted to our department and given topical application of Methylmeta-methyl ointment, applied twice daily for 15 minutes each time to the lesion in the left anterior thyroid region of the neck, for 7 consecutive days. He felt some reduction in the anterior neck pain. He continued using the ointment for another 7 days, and the symptoms further improved, with the anterior neck pain essentially relieved.

[0062] Example 8

[0063] Case 3 involved the use of the traditional Chinese medicine preparation (3#) prepared in Example 3 for the treatment of subacute thyroiditis.

[0064] Ms. Zhou, 62 years old, had been suffering from subacute thyroiditis for over 8 months. Over 8 months prior, she developed left-sided neck pain accompanied by fever without any obvious cause. She received oral corticosteroids at another hospital, which relieved the pain. Three months prior, after contracting COVID-19, she developed right-sided anterior neck pain, with a palpable mass in the right anterior neck area. She received oral corticosteroids at another hospital, which relieved the pain. During the tapering of the corticosteroids, she experienced a recurrence of dull pain in the right anterior neck area, which was more pronounced when swallowing. Currently, corticosteroids have been discontinued, but the dull pain in the right anterior neck area recurs, worsening at night and lessening during the day. She has no fever, palpitations, or hand tremors. She was admitted to our department and given topical application of "Methylene Thyroid Ointment," applied twice daily for 15 minutes each time to the lesion in the right anterior thyroid region, for 7 consecutive days. She reported some relief from the neck pain and continued use for another 14 days, resulting in further improvement of the above symptoms and near-complete relief of the neck pain.

[0065] Example 9

[0066] Case 4 involved the use of the traditional Chinese medicine preparation (4#) prepared in Example 4 for the treatment of subacute thyroiditis.

[0067] Mr. Xu, male, 36 years old, presented with subacute thyroiditis for over a month. Over a month prior, he developed a swelling in the left anterior thyroid region of his neck without any obvious cause, accompanied by fever and palpitations. He was prescribed metoprolol 47.5mg orally once daily at another hospital, but reported that the left thyroid mass had not shrunk, and he experienced a pulling sensation and mild pain during neck movement, along with a low-grade fever in the afternoon. He was admitted to our department and given topical application of methylene blue ointment, applied twice daily for 15 minutes each time, for 7 consecutive days. He reported a reduction in the pulling sensation in his neck, a slight reduction in the size of the left thyroid mass, and significant relief from the pain in the left anterior neck. He continued application for 14 days, and the pulling sensation and pain in the neck were largely relieved, with the left thyroid mass shrinking further. He continued application for another 7 days, and the left thyroid mass shrank significantly.

[0068] Example 10

[0069] Case 5 involved the use of the traditional Chinese medicine preparation (5#) prepared in Example 5 for the treatment of subacute thyroiditis.

[0070] Mr. Yu, male, 56 years old, had been suffering from subacute thyroiditis for over a month. More than a month prior, he developed pain in the left anterior neck without any obvious cause, accompanied by fever. He did not receive regular treatment, and when the pain became unbearable, he would temporarily take one nonsteroidal anti-inflammatory drug (NSAID). He reported that the above symptoms were recurrent and did not improve. He was admitted to our department and given topical application of "Methylene Thyroid Ointment," applied twice daily for 15 minutes each time to the lesion in the left anterior thyroid region of the neck, for 7 consecutive days. He felt that the pain in the anterior neck and the fever had lessened. He continued to use it for another 7 days, and the fever subsided, the pain in the anterior neck further improved, and the pain in the anterior neck was essentially relieved.

[0071] In summary, based on multiple clinical cases from our department, the traditional Chinese medicine preparation of this invention for treating subacute thyroiditis can significantly improve pain and reduce neck lumps, demonstrating a remarkable therapeutic effect on subacute thyroiditis.

[0072] The above embodiments are merely preferred embodiments of the present invention and are not intended to limit the scope of protection of the present invention. Therefore, all equivalent changes made in accordance with the structure, shape, and principle of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine composition for treating subacute thyroiditis, characterized in that, The traditional Chinese medicine composition is made of the following traditional Chinese medicine raw materials in the following mass ratio: Radix Bupleuri 9-12 parts; Radix Paeoniae Rubra 10-15 parts; Radix Isatidis 10-15 parts; Scrophulariae 9-12 parts; Herba Veratrifolii 10-15 parts; Herba Reineckiae 10-15 parts; Radix Sophorae Tonkinensis 3-6 parts; Radix Anemarrhenae 6-9 parts; Fructus Rubi 10-15 parts; The traditional Chinese medicine composition is administered externally.

2. An external use traditional Chinese medicine preparation for treating subacute thyroiditis, characterized in that, The traditional Chinese medicine raw materials in the above ratio are mixed with a pharmaceutically acceptable carrier to form a traditional Chinese medicine preparation.

3. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 2, characterized in that, The traditional Chinese medicine preparation is an ointment.

4. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 3, characterized in that, The ointment is prepared by the following method: the traditional Chinese medicine raw materials are weighed, dried at low temperature, ground into powder, sieved through a 100-mesh sieve, mixed with a mixed base, stirred uniformly after being heated and melted, sieved through an 80-mesh sieve after being cooled, filtered, and then placed in a container to solidify naturally to form an ointment, which is then divided into portions for use.

5. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 4, characterized in that, The mixed base is a mixture of white petrolatum, azone, glycerol, and lanolin, and the components are as follows in mass: White petrolatum 10 parts; Azone 1 part; Glycerol 1 part; Lanolin 10 parts.

6. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 5, characterized in that, The volume ratio of the powder to the mixed base is 1:

1.

7. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 2, characterized in that, The traditional Chinese medicine preparation is an external patch.

8. The Chinese medicinal preparation for treating subacute thyroiditis according to claim 7, characterized in that, The ointment of any one of claims 3-6 is spread on a non-woven fabric to form an external patch.