A device for preparing a self-allogeneic cross-linked leather

The autologous-allogeneic cross-linked skin preparation device simplifies the skin grafting process of autologous and allogeneic skin, achieving precise alignment and fixation of autologous and allogeneic skin, solving the problems of complex operation and uneven spacing in the existing technology, and improving the efficiency and effect of skin grafting.

CN118081904BActive Publication Date: 2026-06-02FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
Filing Date
2024-04-15
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing technologies for autologous and allogeneic skin grafting involve complex and time-consuming processes, which are not conducive to the rescue of patients with large-area burns. Furthermore, manual skin grafting makes it difficult to ensure equal spacing.

Method used

An apparatus for preparing autologous and allogeneic cross-linked skin was designed, including a base and a pressure plate. The pressure plate has a first positioning area to fix the autologous skin, and the base has a second positioning area to fix the allogeneic skin. The autologous skin and allogeneic skin are precisely aligned and fixed through a negative pressure chamber and an air-leakage prevention module, simplifying the operation process.

Benefits of technology

It reduces the operational difficulty for medical staff, improves the production efficiency and uniformity of autologous cross-linked skin, saves time, and is beneficial to the skin grafting and rehabilitation of injured patients.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a kind of self-allogeneic crosslinked leather preparation devices, comprising: preparation device main body, the preparation device main body includes base and pressing plate, the pressing plate is movably configured on base, the inner wall of the pressing plate is configured with a plurality of first positioning area for fixing autologous skin, the inner wall of the base is configured with second positioning area for fixing allogeneic skin.The self-allogeneic crosslinked leather preparation device of the application, medical staff when using pressing plate to base buckling, and then the autologous skin in first positioning area can be embedded into the reserved square mouth of allogeneic skin, to realize the process of autologous skin and allogeneic skin to make self-allogeneic crosslinked leather.The operation difficulty of medical staff is reduced by the design of the above structure, so that the process of making self-allogeneic crosslinked leather is relatively simple and efficient, saves time;Since the above device replaces manual production, so that self-allogeneic crosslinked leather has neat, equal spacing, which is beneficial to the skin grafting rehabilitation of patient.
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Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically, to an apparatus for preparing autologous cross-linked skin. Background Technology

[0002] Skin grafting is generally used for burn treatment. Autologous skin grafting is the best choice for skin grafting. However, when the burn area is too large, autologous skin cannot provide enough skin grafts. In this case, allogeneic skin is needed. Allogeneic skin can act as a barrier to prevent a drop in body temperature, excessive water loss, large loss of protein, and endocrine and immune system disorders.

[0003] Chinese invention patent application No. 202211100130.3 discloses a method for mixed autologous and allogeneic MEEK skin graft transplantation, solving the technical problem of insufficient skin source for patients with large-area burns. Prepared autologous and allogeneic MEEK skin grafts are taken and alternately implanted into the wound bed after debridement. The autologous graft is the patient's own skin, and the allogeneic graft is skin donated by a relative. Both the prepared autologous and allogeneic MEEK skin grafts are cut into single-row strips. Multiple strips of allogeneic MEEK skin grafts are implanted into the wound bed after debridement at intervals of 0.5-0.8 cm, and then autologous MEEK skin grafts are implanted into the intervals between the allogeneic MEEK skin grafts. However, the above-mentioned technical solution involves implanting strips of allogeneic skin at certain intervals onto the wound bed after debridement, and then implanting autologous skin into the intervals between the allogeneic skin. The skin grafting process is complicated, wastes time, and is not conducive to the rescue of the injured. Furthermore, manual skin grafting cannot guarantee equal spacing.

[0004] Therefore, it is necessary to propose a device for preparing a self-heterogeneous cross-linked skin to solve the problems existing in the prior art. Summary of the Invention

[0005] The summary section introduces a series of simplified concepts, which will be further explained in detail in the detailed description section. The summary section of this invention is not intended to limit the key features and essential technical features of the claimed technical solution, nor is it intended to determine the scope of protection of the claimed technical solution.

[0006] To at least partially solve the above problems, the present invention provides an apparatus for preparing autologous cross-linked skin, comprising: a main body of the apparatus, the main body of the apparatus including a base and a pressure plate, the pressure plate being movably disposed on the base, the inner wall of the pressure plate being provided with a plurality of first positioning areas for fixing autologous skin, and the inner wall of the base being provided with a second positioning area for fixing allogeneic skin.

[0007] According to an embodiment of the present invention, the self-crosslinking skin preparation apparatus has a square knife in the first positioning area, a negative pressure cavity is arranged in the pressure plate, a negative pressure hole is arranged in the square knife, and the negative pressure hole communicates with the negative pressure cavity. The pressure plate is connected to an external negative pressure device through an air leakage prevention module.

[0008] According to an embodiment of the present invention, in the self-crosslinking skin preparation apparatus, a groove is formed in the second positioning area, and a carrier plate is disposed in the groove. The size of the carrier plate is smaller than the size of the groove, and the four sides of the carrier plate are equidistant from the four inner walls of the groove.

[0009] According to an embodiment of the present invention, the self-crosslinked skin preparation apparatus has a plurality of intersecting horizontal and vertical grooves on the carrier plate. The number of horizontal grooves is the same as the number of rows of the square blade, and the number of vertical grooves is the same as the number of columns of the square blade. The intersection of the horizontal and vertical grooves corresponds to the center point of the square blade, and the depth of the horizontal and vertical grooves is greater than the height of the square blade.

[0010] According to an embodiment of the present invention, in the apparatus for preparing a cross-linked skin, a square frame is movably arranged around the carrier plate, and cross-shaped and longitudinal gauze fabrics are arranged on the square frame at positions corresponding to the transverse and longitudinal grooves.

[0011] According to an embodiment of the present invention, an anti-leakage module is disposed on one outer wall of the pressure plate. The anti-leakage module includes a first anti-leakage cylinder, a second anti-leakage cylinder, and an outer anti-leakage cap. The outer anti-leakage cap has an internal space for accommodating the second anti-leakage cylinder and the first anti-leakage cylinder. The inner end of the first anti-leakage cylinder passes through the negative pressure chamber. The outer anti-leakage cap is disposed at the outer end of the first anti-leakage cylinder. The inner end of the second anti-leakage cylinder is disposed inside the outer anti-leakage cap. The outer end of the second anti-leakage cylinder is connected to an external negative pressure device.

[0012] According to the self-crosslinking skin preparation apparatus of the present invention, the outer leak-proof cap is further provided with two inner leak-proof caps, the two inner leak-proof caps respectively corresponding to the outer end of the first leak-proof cylinder and the inner end of the second leak-proof cylinder, and the inner leak-proof caps are provided with internal air holes.

[0013] According to an embodiment of the present invention, the self-crosslinking skin preparation apparatus includes an inner leak-proof cap comprising a cap plate and a cap tube, the cap tube having an inner air hole, a first spring disposed on the cap tube, the first spring abutting between the cap plate and the cap tube, and the cap plate having a groove.

[0014] According to an embodiment of the present invention, the self-crosslinking leather preparation apparatus has a circumferential groove inside the outer leak-proof cap, a pre-tightening support plate is disposed in the circumferential groove, the pre-tightening support plate has a cylindrical hole in the middle corresponding to the cap cylinder, the pre-tightening support plate also has a plurality of auxiliary pre-tightening holes, the plurality of auxiliary pre-tightening holes are evenly distributed around the cylindrical hole, and a second spring is disposed in the auxiliary pre-tightening hole, the second spring abutting against the cap plate.

[0015] According to an embodiment of the present invention, in the self-crosslinking skin preparation apparatus, the outer end of the first leak-proof cylinder and the inner end of the second leak-proof cylinder are circumferentially arranged with a plurality of first tongue teeth and a plurality of second tongue teeth, the plurality of first tongue teeth and second tongue teeth being staggered. The outer leak-proof cap has an outer port corresponding to one end of the second leak-proof cylinder and an inner port corresponding to the outer end of the first leak-proof cylinder. The outer port and the inner port are each provided with a first inner tongue notch corresponding to the first tongue teeth and a second inner tongue notch corresponding to the second tongue teeth. The interior of the outer leak-proof cap has a through space to accommodate the second leak-proof cylinder and the first leak-proof cylinder.

[0016] Compared with the prior art, the present invention has at least the following beneficial effects:

[0017] This invention provides an apparatus for preparing autologous-to-allogeneic cross-linked skin. The apparatus includes a main body comprising a base and a pressure plate. The pressure plate is movably mounted on the base. To place the autologous skin onto the inner wall of the pressure plate, multiple first positioning areas are provided on the inner wall of the pressure plate to fix the autologous skin. Second positioning areas are provided on the inner wall of the base to fix the allogeneic skin. After medical personnel use instruments to place the autologous skin entirely into the first positioning areas and fix the allogeneic skin into the second positioning areas, the pressure plate is then snapped onto the base. The autologous skin in the first positioning areas can then be inserted into a pre-reserved square opening in the allogeneic skin, thus realizing the process of jointly preparing autologous-to-allogeneic cross-linked skin using both autologous and allogeneic skin. This structural design reduces the operational difficulty for medical personnel, making the process of preparing autologous-to-allogeneic cross-linked skin simpler, more efficient, and time-saving. Since this apparatus replaces manual preparation, the autologous-to-allogeneic cross-linked skin has neat and even spacing, which is beneficial for the skin grafting and rehabilitation of injured patients.

[0018] The self-crosslinked skin preparation apparatus of the present invention, other advantages, objectives and features of the present invention will be apparent in part from the following description, and in part will be understood by those skilled in the art through study and practice of the present invention. Attached Figure Description

[0019] The accompanying drawings are provided to further illustrate the invention and form part of the specification. They are used in conjunction with embodiments of the invention to explain the invention and do not constitute a limitation thereof. In the drawings:

[0020] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0021] Figure 2 This is a schematic diagram of the internal structure of the pressure plate in this invention.

[0022] Figure 3 This is a schematic diagram of the structure of the carrier plate in this invention.

[0023] Figure 4 This is a schematic diagram of the square frame structure in this invention.

[0024] Figure 5 This is a schematic diagram of the connection structure between the main body of the preparation device and the external negative pressure device in this invention.

[0025] Figure 6 This is a schematic diagram of the anti-leakage module in this invention.

[0026] Figure 7 This is a schematic diagram of the exploded structure of the anti-leakage module in this invention.

[0027] Figure 8 For the present invention Figure 7 A magnified structural diagram of part A in the middle.

[0028] Figure 9 This is a schematic diagram of the structure of the inner leak-proof cap inside the outer leak-proof cap in this invention.

[0029] Figure 10 For the present invention Figure 9 A magnified structural diagram of part B in the diagram.

[0030] Figure 11 This is a schematic diagram of the structure of the inner leak-proof cap in this invention.

[0031] Figure 12 This is a schematic diagram of the structure of the first inner tongue notch in this invention.

[0032] Figure 13 This is a schematic diagram of the internal limiting mechanism in this invention.

[0033] Figure 14 This is a schematic diagram of the connection structure between the first tongue tooth and the inner limiting mechanism in this invention. Figure 1 .

[0034] Figure 15 This is a schematic diagram of the connection structure between the first tongue tooth and the inner limiting mechanism in this invention. Figure 2 . Detailed Implementation

[0035] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments, so that those skilled in the art can implement it based on the description.

[0036] It should be understood that terms such as “having,” “comprising,” and “including” as used herein do not exclude the presence or addition of one or more other elements or combinations thereof.

[0037] like Figure 1 As shown, the present invention provides an apparatus for preparing autologous and allogeneic cross-linked skin, comprising: a main body 100 of the apparatus, which includes a base 1 and a pressure plate 2. Specifically, the pressure plate 2 is movably mounted on the base 1. Preferably, one side of the pressure plate 2 is hinged to one side of the base 1, so that the pressure plate 2 can be opened upward to place autologous or allogeneic skin for the preparation of autologous and allogeneic cross-linked skin. In order to place the autologous skin on the inner wall of the pressure plate 2, a plurality of first positioning areas 2 are provided on the inner wall of the pressure plate 2. 1. The first positioning area 21 can fix the autologous skin. Correspondingly, a second positioning area 11 is set on the inner wall of the base 1, which fixes the allogeneic skin. Then, when medical staff use instruments to place the autologous skin into the first positioning area 21 and fix the allogeneic skin into the second positioning area 11, the pressure plate 2 is then fastened to the base 1. The autologous skin in the first positioning area 21 can then be inserted into the reserved square opening of the allogeneic skin, thereby realizing the process of creating autologous-allogeneic cross-linked skin with autologous and allogeneic skin. Through the design of the above structure, the operation difficulty of medical staff is reduced, making the process of creating autologous-allogeneic cross-linked skin simpler, more efficient, and time-saving. Since the above device replaces manual production, the autologous-allogeneic cross-linked skin has a neat and even spacing, which is beneficial to the skin grafting rehabilitation of the injured.

[0038] It is understandable that, in order to fix the allogeneic skin in the second positioning area 11, medical adhesive can be applied to the second positioning area 11, so that the allogeneic skin can be temporarily fixed.

[0039] Exemplary pressure plate

[0040] like Figure 1 As shown, in some embodiments of the present invention, a square blade 22 is installed in the first positioning area 21 of the pressure plate 2. The installed square blade 22 increases the functionality of the autologous-allogeneic cross-linked skin preparation device, enabling the device to cut large pieces of allogeneic skin to create pre-reserved square openings on the allogeneic skin. Alternatively, large pieces of autologous skin can be fixed in the second positioning area 11, and small pieces of autologous skin can be cut out using the aforementioned multiple square blades 22. This device can achieve the cutting of autologous and allogeneic skin, greatly improving cutting efficiency, reducing the operational difficulty for medical personnel, and ensuring good consistency of autologous skin, which is more conducive to subsequent skin grafting operations and skin graft recovery.

[0041] like Figures 1-2As shown, further, in order to improve the fixing ability of the pressure plate 2 on the autologous skin and prevent the autologous skin from detaching from the square blade 22, a negative pressure cavity 23 is also provided in the pressure plate 2 in this embodiment. Correspondingly, a negative pressure hole 24 is provided in the square blade 22, and the negative pressure hole 24 is connected to the negative pressure cavity 23. The pressure plate 2 is connected to the external negative pressure device through the anti-leakage module 5. Therefore, medical staff can first start the external negative pressure device to perform negative pressure suction on the negative pressure cavity 23. As a result, the negative pressure holes 24 in the multiple square blades 22 also have negative pressure adsorption capacity. So when the autologous skin is placed in the square blade 22, it can be adsorbed by negative pressure in the square blade 22, thereby increasing the fixing ability of the pressure plate 2. After the pressure plate 2 is fastened to the base 1, the medical staff can turn off the external negative pressure device. Due to the action of the medical adhesive, the autologous skin is embedded into the reserved square opening of the allogeneic skin.

[0042] Furthermore, the aforementioned anti-leakage module 5 provides an anti-leakage function at the connection point of the pressure plate 2 to prevent air leakage during negative pressure adsorption, which would reduce the negative pressure and cause the autologous skin to detach from the square knife 22.

[0043] Exemplary base

[0044] like Figure 1 , Figure 3 As shown, in some embodiments of the present invention, a groove 12 is provided in the second positioning area 11 of the base 1, and a carrier plate 3 is installed in the groove 12. Preferably, the carrier plate 3 can be made of soft rubber, soft silicone, soft plastic, cork board or other materials. The thickness of the carrier plate 3 is the same as the depth of the groove 12, the size of the carrier plate 3 is smaller than the size of the groove 12, and the distances from the four sides of the carrier plate 3 to the four inner walls of the groove 12 are equal. Here, the carrier plate 3 is used as a carrier plate for allogeneic skin, which makes it convenient for medical staff to use multiple carrier plates 3 to fix multiple allogeneic skins separately. Then, the carrier plate 3 is placed in the groove 12 and the pressure plate 2 is used to cut and inlay the autologous skin, which greatly improves the ease of operation of the device.

[0045] Preferably, multiple horizontal grooves 31 and multiple vertical grooves 32 are formed on the aforementioned carrier plate 3. These horizontal grooves 31 and vertical grooves 32 intersect each other. The number of horizontal grooves 31 is the same as the number of rows of the square blade 22, and the number of vertical grooves 32 is the same as the number of columns of the square blade 22. The intersection points of the horizontal grooves 31 and vertical grooves 32 correspond to the center point of the square blade 22. The depth of the horizontal grooves 31 and vertical grooves 32 is greater than the height of the square blade 22. Medical personnel first apply medical supplies to the carrier plate 3. The adhesive is applied, and then the medical staff attaches the allogeneic skin to the carrier plate 3, so that the reserved square opening on the allogeneic skin corresponds to the intersection of the groove 31 and the longitudinal groove 32. After the autologous skin is placed in the square blade 22, the external negative pressure device is activated, and then the pressure plate 2 is fastened to the base 1. The external negative pressure device is then turned off, and the autologous skin of the square blade 22 enters the reserved square opening and comes into contact with the medical adhesive. Then the pressure plate 2 is opened and flipped over from the base plate 1, so that the autologous skin is embedded in the reserved square opening.

[0046] Preferably, the front side of the pressure plate 2 has a handle 25, which makes it convenient for medical staff to fasten the pressure plate 2 to the bottom plate 1 by means of the handle 25 during operation.

[0047] like Figure 4 As shown, preferably, in order to make it easier to remove the autologous or allogeneic crosslinked skin made from the above-mentioned autologous skin or allogeneic skin from the carrier plate 3, in this embodiment, a square frame 4 is movably arranged around the carrier plate 3. Horizontal gauze 41 and longitudinal gauze 42 are installed on the square frame 4. Here, the horizontal gauze 41 and longitudinal gauze 42 are intersecting each other, and the horizontal gauze 41 corresponds to the horizontal groove 31, and the longitudinal gauze 42 corresponds to the longitudinal groove 32.

[0048] When medical staff use the square frame 4, they place it into the groove 12. Then, the horizontal gauze 41 and the vertical gauze 42 are placed at the bottom of the horizontal groove 31 and the vertical groove 32, respectively. The depth of the horizontal groove 31 and the vertical groove 32 is greater than the height of the square knife 22. When the square knife 22 cuts the skin, it will not cut the horizontal gauze 41 and the vertical gauze 42.

[0049] Therefore, when removing the autologous cross-linked skin, the square frame 4 can be lifted from the groove 12. The horizontal gauze 41 and vertical gauze 42 arranged crosswise inside the square frame 4 support the autologous cross-linked skin, and the autologous cross-linked skin is implanted on the wound surface.

[0050] Exemplary leak-proof module

[0051] like Figure 5 As shown, in some embodiments of the present invention, a specific structure of the above-mentioned anti-leakage module 5 is provided. The anti-leakage module 5 with this structure can prevent air leakage from the connection part between the outer wall of the pressure plate 2 and the external negative pressure device 6.

[0052] like Figures 6-7As shown, specifically, the leak-proof module 5 is installed on one outer wall of the pressure plate 2. The leak-proof module 5 includes a first leak-proof cylinder 51, a second leak-proof cylinder 52, and an outer leak-proof cap 53. The outer leak-proof cap 53 has a through-space 50 to accommodate the second leak-proof cylinder 52 and the first leak-proof cylinder 51. The inner end of the first leak-proof cylinder 51 is installed in the negative pressure cavity 23 of the pressure plate 2. Here, the inner end of the first leak-proof cylinder 51 can be fixed to the pressure plate 2 by applying glue. When the second leak-proof cylinder 52 and the first leak-proof cylinder 51 are installed, they are connected by an outer leak-proof cap 53 to prevent air leakage at the connection point. Specifically, the outer leak-proof cap 53 is installed at the outer end of the first leak-proof cylinder 51, and the inner end of the second leak-proof cylinder 52 is installed inside the outer leak-proof cap 53. That is, the outer end of the first leak-proof cylinder 51 and the inner end of the second leak-proof cylinder 52 are both located in the through space 50. The outer end of the second leak-proof cylinder 52 is connected to the external negative pressure device 6.

[0053] Exemplary outer leak-proof cap

[0054] like Figures 7-9 As shown, further, some embodiments of the present invention provide a specific structure of the aforementioned outer leak-proof cap 53. Here, two inner leak-proof caps 54 are also configured inside the outer leak-proof cap 53. The two inner leak-proof caps 54 correspond to the outer end of the first leak-proof cylinder 51 and the inner end of the second leak-proof cylinder 52, respectively. Therefore, when the first leak-proof cylinder 51 and the second leak-proof cylinder 52 are installed inside the outer leak-proof cap 53, the two inner leak-proof caps 54 are compressed by the push of the first leak-proof cylinder 51 and the second leak-proof cylinder 52 and tightly abut against the two to seal them, thereby playing the role of preventing air leakage. In addition, an inner air hole 540 is opened inside the inner leak-proof cap 54, so the negative pressure communication between the two can be achieved through the inner air hole 540.

[0055] Exemplary inner leak-proof cap

[0056] like Figures 9-11As shown, further, some embodiments of the present invention provide a specific structure for the aforementioned inner leak-proof cap 54. This inner leak-proof cap 54 achieves a sealing effect between the first leak-proof cylinder 51 and the second leak-proof cylinder 52. Specifically, the inner leak-proof cap 54 includes a cap plate 541 and a cap tube 542. The cap tube 542 has the aforementioned internal air hole 540, and a first spring 543 is disposed on the cap tube 542. The cap tube 542 is compressible, and the first spring 543 abuts against the cap plate 541 and the cap tube 542. Therefore, when the first leak-proof cylinder 51 and the second leak-proof cylinder 52 enter the outer leak-proof cap 53, they push the cap plate 541 on the inner leak-proof cap 54, thereby compressing the first spring 543, causing the first spring 543 and the cap cylinder 542 to deform, and then the two inner leak-proof caps 54 tightly abut against each other and seal tightly against the first leak-proof cylinder 51 and the second leak-proof cylinder 52. Furthermore, the cap plate 541 also has a groove 544, which can provide space for the cap plate 541 to move due to volume deformation.

[0057] like Figure 9 Furthermore, in this embodiment, the outer leak-proof cap 53 has a circumferential groove 530, and a pre-tightening support plate 58 is installed in the circumferential groove 530. The pre-tightening support plate 58 has a cylindrical hole 581 in the middle, so that the two cap cylinders 542 can correspond to each other in the cylindrical hole 581. The pre-tightening support plate 58 also has a plurality of auxiliary pre-tightening holes 582, which are evenly distributed around the cylindrical hole 581. A second spring 583 is installed in the auxiliary pre-tightening hole 582. The second spring 583 abuts against the cap plate 541. The multiple second springs 583 provide uniform internal support for the cap plate 541, preventing uneven deformation of the inner leak-proof cap 54 and the gap between it and the first leak-proof cylinder 51 or the second leak-proof cylinder 52, which would result in an unreliable sealing and air leakage, thus greatly improving the effect of preventing air leakage.

[0058] like Figures 7-9 , Figure 12 As shown, further, in order to securely install the aforementioned outer leak-proof cap 53 onto the first leak-proof cylinder 51 and the second leak-proof cylinder 52, in this embodiment, preferably, a plurality of first tongue teeth 55 and a plurality of second tongue teeth 56 are circumferentially installed on the outer wall of the outer end of the first leak-proof cylinder 51 and the inner end of the second leak-proof cylinder 52, wherein the plurality of first tongue teeth 55 and second tongue teeth 56 are staggered, that is, there is a second tongue tooth 56 between two first tongue teeth 55, or there is a first tongue tooth 55 between two second tongue teeth 56.

[0059] Correspondingly, the outer leak-proof cap 53 has an outer port 531 corresponding to one end of the second leak-proof cylinder 52 and an inner port 532 corresponding to the outer end of the first leak-proof cylinder 51. In order to cooperate with the first tongue tooth 55 and the second tongue tooth 56, multiple first inner tongue notches 533 and multiple second inner tongue notches 534 are provided in both the outer port 531 and the inner port 532. The first inner tongue notches 533 correspond to the first tongue tooth 55, and the second inner tongue notches 534 correspond to the second tongue tooth 56. So when the outer end of the first leak-proof cylinder 51 and the inner end of the second leak-proof cylinder 52 enter the outer leak-proof cap 53, the first tongue tooth 55 moves along the first inner tongue notch 533, and the second tongue tooth 56 moves along the second inner tongue notch 534, so as to realize the firm connection between the first leak-proof cylinder 51, the second leak-proof cylinder 52 and the outer leak-proof cap 53.

[0060] Preferably, in this embodiment, a first side tongue block 551 is installed on one side of the first tongue tooth 55. Specifically, the first side tongue block 551 faces the second tongue tooth 56. Correspondingly, an inner limiting mechanism 57 is installed at the inner end of the first inner tongue notch 533. So after the first side tongue block 551 enters the first inner tongue notch 533, the first side tongue block 551 will act on the inner limiting mechanism 57, and then the inner limiting mechanism 57 will limit and fix the first side tongue block 551 to prevent the first tongue tooth 55 from disengaging from the first inner tongue notch 533.

[0061] A second side tooth block 561 is installed on the second tongue tooth member 56, with the second side tooth block 561 facing away from the second leak-proof cylinder 52. Correspondingly, an inner tongue groove 535 is opened at the inner end of the second inner tongue notch 534. The second tongue tooth member 56 moves along the second inner tongue notch 534 so that the second side tooth block 561 enters the inner tongue groove 535. The inner tongue groove 535 also limits and fixes the second side tooth block 561. Through the design of the above structure, the outer leak-proof cap 53 can be firmly connected with the first leak-proof cylinder 51 and the second leak-proof cylinder 52, which can provide better support for the inner leak-proof cap 54 and play a role in preventing air leakage.

[0062] Exemplary inner limit mechanism

[0063] like Figures 13-15 As shown, further, some embodiments of the present invention provide a specific structure of the above-mentioned inner limiting mechanism 57. The inner limiting mechanism 57 of this structure includes an inner tongue block 571 and an inner spring post 572. The inner spring post 572 has an inverted T-shaped post 573 and a third spring 574. Here, the inverted T-shaped post 573 is installed in the inner limiting hole 536 of the first inner tongue notch 533, the inner tongue block 571 is installed in the inner receiving groove 537 of the first inner tongue notch 533 and connected to the inverted T-shaped post 573, and the third spring 574 is sleeved on the inverted T-shaped post 573 and located between the inner tongue block 571 and the inner receiving groove 537.

[0064] Therefore, when the first side tongue block 551 contacts the inner tongue block 571, as the first tongue tooth 55 continues to move in the first inner tongue notch 533, the first side tongue block 551 presses the inner tongue block 571, causing the inner tongue block 571 to also press the inner spring post 572 and enter the inner storage groove 537. Then, the first side tongue block 551 moves to the inner end of the first inner tongue notch 533. Then, under the elastic force of the inner spring post 572, the inner tongue block 571 moves outward from the inner storage groove 537 and intercepts and fixes the first side tongue block 551 in the first inner tongue notch 533. This achieves the limiting and fixing of the first tongue tooth 55 by the inner limiting mechanism 57, preventing loosening between the first leak-proof cylinder 51, the second leak-proof cylinder 52 and the outer leak-proof cap 53 during use.

[0065] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0066] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0067] Although embodiments of the present invention have been disclosed above, they are not limited to the applications listed in the specification and embodiments. They can be applied to various fields suitable for the present invention. Other modifications can be easily made by those skilled in the art. Therefore, without departing from the general concept defined by the claims and their equivalents, the present invention is not limited to the specific details and illustrations shown and described herein.

Claims

1. An apparatus for preparing a self-crosslinked skin, characterized in that, include: The main body (100) of the preparation device includes a base (1) and a pressure plate (2). The pressure plate (2) is movably disposed on the base (1). The inner wall of the pressure plate (2) is provided with a plurality of first positioning areas (21) for fixing autologous skin. The inner wall of the base (1) is provided with a second positioning area (11) for fixing allogeneic skin. The first positioning area (21) has a square blade (22), the pressure plate (2) is equipped with a negative pressure chamber (23), the square blade (22) is equipped with a negative pressure hole (24), and the negative pressure hole (24) is connected to the negative pressure chamber (23). The pressure plate (2) is connected to an external negative pressure device (6) through a leak-proof module (5).

2. The apparatus for preparing a self-crosslinked skin according to claim 1, characterized in that, The second positioning area (11) has a groove (12) and a carrying plate (3) is arranged in the groove (12). The size of the carrying plate (3) is smaller than the size of the groove (12), and the four sides of the carrying plate (3) are equidistant from the four inner walls of the groove (12).

3. The apparatus for preparing a self-crosslinked skin according to claim 2, characterized in that, The loading plate (3) is provided with a plurality of horizontal grooves (31) and a plurality of vertical grooves (32) that intersect horizontally and vertically. The number of horizontal grooves (31) is the same as the number of rows of the square blade (22), and the number of vertical grooves (32) is the same as the number of columns of the square blade (22). The intersection of the horizontal grooves (31) and the vertical grooves (32) is set to correspond to the center point of the square blade (22). The depth of the horizontal grooves (31) and the vertical grooves (32) is greater than the height of the square blade (22).

4. The apparatus for preparing a self-crosslinked skin according to claim 3, characterized in that, The loading plate (3) is movably arranged with a square frame (4) around it. On the square frame (4), there are intersecting horizontal gauze (41) and vertical gauze (42) at positions corresponding to the horizontal groove (31) and the vertical groove (32).

5. The apparatus for preparing a self-crosslinked skin according to claim 1, characterized in that, An air leak prevention module (5) is provided on one side of the outer wall of the pressure plate (2). The air leak prevention module (5) includes a first air leak prevention cylinder (51), a second air leak prevention cylinder (52), and an outer air leak prevention cap (53). The outer air leak prevention cap (53) has a through space (50) for accommodating the second air leak prevention cylinder (52) and the first air leak prevention cylinder (51). The inner end of the first air leak prevention cylinder (51) is inserted into the negative pressure chamber (23). The outer air leak prevention cap (53) is disposed at the outer end of the first air leak prevention cylinder (51). The inner end of the second air leak prevention cylinder (52) is disposed in the outer air leak prevention cap (53). The outer end of the second air leak prevention cylinder (52) is connected to an external negative pressure device.

6. The apparatus for preparing a self-crosslinked skin according to claim 5, characterized in that, The outer leak-proof cap (53) is also equipped with two inner leak-proof caps (54), which correspond to the outer end of the first leak-proof cylinder (51) and the inner end of the second leak-proof cylinder (52), respectively, and the inner leak-proof cap (54) is provided with an inner air hole (540).

7. The apparatus for preparing a self-crosslinked skin according to claim 6, characterized in that, The inner leak-proof cap (54) includes a cap plate (541) and a cap tube (542). The cap tube (542) has an inner air hole (540). A first spring (543) is disposed on the cap tube (542). The first spring (543) abuts against the cap plate (541) and the cap tube (542). The cap plate (541) has a groove (544).

8. The apparatus for preparing a self-crosslinked skin according to claim 7, characterized in that, The outer leak-proof cap (53) has a circumferential groove (530) inside, and a pre-tightening support plate (58) is arranged inside the circumferential groove (530). The pre-tightening support plate (58) has a cylindrical hole (581) in the middle corresponding to the cap cylinder (542). The pre-tightening support plate (58) also has a plurality of auxiliary pre-tightening holes (582). The plurality of auxiliary pre-tightening holes (582) are evenly distributed around the cylindrical hole (581). A second spring (583) is arranged inside the auxiliary pre-tightening hole (582), and the second spring (583) abuts against the cap cylinder (541).

9. The apparatus for preparing a self-crosslinked skin according to claim 5, characterized in that, The outer end of the first leak-proof cylinder (51) and the inner end of the second leak-proof cylinder (52) are circumferentially provided with a plurality of first tongue teeth (55) and a plurality of second tongue teeth (56). The plurality of first tongue teeth (55) and second tongue teeth (56) are staggered. The outer leak-proof cap (53) has an outer port (531) corresponding to one end of the second leak-proof cylinder (52) and an inner port (532) corresponding to the outer end of the first leak-proof cylinder (51). The outer port (531) and the inner port (532) are each provided with a first inner tongue notch (533) corresponding to the first tongue teeth (55) and a second inner tongue notch (534) corresponding to the second tongue teeth (56).