A medical clinical tumor biopsy sampling device
By designing a combination of a hollow puncture needle and a sampling needle core in the tumor biopsy sampling device, and utilizing an inclined sampling port and negative pressure adsorption technology, the problem of tumor tissue damage during the sampling process was solved, achieving efficient and safe tumor sampling.
Patent Information
- Application Number
- CN202410436798.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-12
- Publication Date
- 2025-11-07
- Estimated Expiration
- 2044-04-12
AI Technical Summary
Existing tumor biopsy sampling devices cause excessive interference to tumor tissue during the sampling process, leading to tumor damage and endangering patient safety.
A device comprising a hollow puncture needle and a sampling needle core was designed. The sampling needle core slides and rotates inside the hollow puncture needle. The sharp edge of the inclined sampling port applies compressive and shear stress to the tumor tissue. The relative movement of the piston and the rotating component generates negative pressure to adsorb the tumor tissue, reducing disturbance to the tumor.
It reduces disturbance to tumor tissue, improves sampling success rate and quality, and enhances patient protection.
Smart Images
Figure CN118161202B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical devices, and particularly relates to a medical clinical tumor biopsy sampling device. BACKGROUND
[0002] Tumor biopsy is to take a small amount of tissue from the tumor tissue of a patient to make pathological sections, and then observe the tumor cells and tissue structure under a microscope to determine the nature, histological type and differentiation degree of the tumor, so as to provide reliable data for clinical treatment.
[0003] The existing tumor biopsy sampling device is mostly to insert a hollow needle and a core needle inserted into the hollow needle into the tumor tissue of a patient, a groove is usually arranged on the core needle for storing tumor tissue, and then the hollow needle is used to cut and sample the tumor tissue stored in the groove of the core needle. Since the existing hollow needle causes secondary disturbance to the tumor tissue of the adjacent region in the subsequent sampling process after being inserted into the tumor tissue, the sampling method causes too much disturbance to the tumor tissue of the adjacent region, the tumor tissue suffers unnecessary disturbance, the tumor is excessively disturbed, the tumor is damaged, and the life safety of the patient is even endangered. SUMMARY
[0004] In order to overcome the defects that the existing tumor biopsy sampling device causes too much disturbance to the tumor tissue in the sampling process, the tumor is damaged, and the life safety of the patient is endangered, the present application provides a medical clinical tumor biopsy sampling device.
[0005] The technical scheme is as follows: a medical clinical tumor biopsy sampling device, comprising a shell, a flip cover rotatably connected to one side of the shell, a stop lever rotatably connected to the flip cover, a bent lever arranged on one side of the shell and limitedly matched with the stop lever, a hollow puncture needle fixedly connected to one side of the shell close to the flip cover, the shell and the hollow puncture needle being in contact with the flip cover, an inlaying opening arranged on one side of the hollow puncture needle away from the shell, a sampling needle core slidably and rotatably connected in the hollow puncture needle, a sampling opening arranged on one side of the sampling needle core close to the inlaying opening, a rotating piece rotatably connected in the shell, a first mark arranged on one side of the sampling needle core close to the rotating piece, a second mark arranged on one side of the rotating piece close to the hollow puncture needle, and a power mechanism arranged on the shell and used for rotating the sampling needle core.
[0006] As an improvement of the above scheme, the inlaying opening and the sampling opening are respectively deflected to one side along the outer wall of the hollow puncture needle and the outer wall of the sampling needle core, so as to make the sharp edge of the sampling opening exert additional shear stress on the target.
[0007] As an improvement of the above-mentioned solution, the power mechanism comprises a sliding rod, the sliding rod is limitingly and slidingly connected to the side of the shell away from the hollow puncture needle, the sliding rod is slidingly connected with the rotating piece and is limitingly matched, the side of the sliding rod away from the rotating piece is provided with a moving block, the first elastic element is fixedly connected between the sliding rod and the shell, the rotating piece is provided with a limiting groove, the sampling needle core is fixedly connected with a first limiting block in an annular array on the side close to the rotating piece, the first limiting blocks in the annular array are limitingly matched with the rotating piece, the end of the sliding rod close to the rotating piece is fixedly connected with a limiting column, the limiting column is limitingly matched with the limiting groove, and the shell is provided with a limiting assembly for limiting the sliding rod.
[0008] As an improvement of the above-mentioned solution, the limiting groove is helical, and the helical pitch angle of the limiting groove gradually changes from the side close to the hollow puncture needle to the other side, so as to make the hollow puncture needle rotate at a gradually changing speed.
[0009] As an improvement of the above-mentioned solution, the limiting assembly comprises a sliding ring, the sliding ring is slidingly connected to the side of the shell away from the hollow puncture needle, the shell is slidingly connected with a button and a sliding rod, the button and the sliding rod are fixedly connected with the sliding ring, the second elastic element is fixedly connected between the sliding rod and the shell, the spring block is installed on the side of the sliding ring close to the sliding rod, the sliding rod is fixedly connected with a second limiting block, and the second limiting block is limitingly matched with the spring block.
[0010] As an improvement of the above-mentioned solution, further comprising an adsorption mechanism for adsorbing the target object, the adsorption mechanism is arranged on the rotating piece, the adsorption mechanism comprises a piston, the piston is sealingly and slidingly connected to the rotating piece, the end of the sliding rod close to the piston is rotatably connected with a connecting frame, the side of the connecting frame away from the sliding rod is fixedly connected with a moving ring, the moving ring is slidingly connected with the piston, the rotating piece is fixedly connected with a limiting frame, the limiting frame is slidingly connected with the connecting frame, the side of the piston close to the limiting frame is fixedly connected with a magnetic block, the magnetic block is magnetically matched with the moving ring, the third elastic element is fixedly connected between the magnetic block and the limiting frame, the first air channel is arranged in the sampling needle core, the first air channel is communicated with the rotating piece, the second air channel arranged at equal intervals is arranged on the side of the sampling needle core away from the shell, the second air channels arranged at equal intervals are all communicated with the first air channel, the adsorption holes arranged uniformly are arranged on the side of the sampling needle core away from the shell, the adsorption holes are located in the sampling port, the adsorption holes arranged uniformly are respectively communicated with adjacent second air channels, and the sealing assembly for sealing the rotating piece itself is arranged in the rotating piece.
[0011] As an improvement of the above-mentioned scheme, the moving ring is made of copper and is used to drive the magnetic block to move differently according to whether the magnetic force exists.
[0012] As an improvement of the above-mentioned scheme, the sealing assembly comprises a first sealing member fixedly connected to the sampling needle core on the side close to the rotating member, and a second sealing member fixedly connected to the rotating member on the side close to the first sealing member.
[0013] As an improvement of the above-mentioned scheme, a limiting ring is slidingly connected in the shell, the limiting ring is rotationally connected with the rotating member, and mirror-image arranged fourth elastic elements are fixedly connected between the limiting ring and the shell.
[0014] As an improvement of the above-mentioned scheme, the blocking assembly comprises mirror-image arranged limiting frames fixedly connected in the shell, limiting rods slidingly connected with the limiting frames, springs fixedly connected between the limiting rods and the adjacent limiting frames, third limiting blocks fixedly connected to one end of the limiting rods close to the limiting ring, the mirror-image arranged third limiting blocks are limitingly matched with the limiting ring, extrusion blocks fixedly connected to the side of the sliding rods close to the rotating member, and the mirror-image arranged limiting rods are limitingly matched with the extrusion blocks.
[0015] The present application has the following beneficial effects: the sampling needle core is arranged in the hollow puncture needle, so that the interference area of the tumor during sampling is avoided to be too large, the damage and dispersion of the tumor caused by too large disturbance are reduced, the local disturbance of the tumor to be sampled is performed by the rotation of the hollow puncture needle, the influence on the tumor body is reduced, and the protection of the patient is enhanced; the sharp edge of the sampling port arranged obliquely exerts pressure stress and shear stress on the adjacent tumor during the rotation sampling, so that the smoothness during sampling of the tumor tissue is improved; the relative movement of the piston and the rotating member causes the suction force in the plurality of adsorption holes, so that the tumor tissue in the adjacent area is adsorbed, the tumor tissue smoothly enters the sampling port, sufficient tumor tissue is provided for subsequent cutting, and the success rate and sampling quality of the tumor sampling are improved; the limiting ring is pulled by the mirror-image arranged fourth elastic elements and limited by the mirror-image arranged third limiting blocks, so that the normal negative pressure environment in the first air duct is ensured, the unexpected movement of the rotating member is prevented, the first air duct is prevented from losing the adsorption of the tumor tissue due to pressure relief, the plurality of adsorption holes smoothly adsorb the tumor tissue in the adjacent area, the tumor tissue in the cutting area smoothly enters the sampling port, and the success rate and sampling quality of the sampling are improved. BRIEF DESCRIPTION OF DRAWINGS
[0016] Figure 1 Schematic view of the three-dimensional structure of the whole application;
[0017] Figure 2 Schematic view of the three-dimensional structure of the shell of the application;
[0018] Figure 3 Schematic view of the three-dimensional structure of the hollow puncture needle and the sampling needle core of the application;
[0019] Figure 4 Schematic view of the three-dimensional structure of the shell and the internal parts of the application;
[0020] Figure 5 Schematic view of the three-dimensional structure of the rotating member and the upper parts of the application; Figure 4 Enlarged view of the three-dimensional structure of A in the application;
[0021] Figure 6 Schematic view of the three-dimensional structure of the rotating member and the upper parts of the application;
[0022] Figure 7 Schematic view of the three-dimensional structure of the shell and the internal parts of the application;
[0023] Figure 8 Schematic view of the three-dimensional structure of the sampling needle core and the features thereof of the application;
[0024] Figure 9 Schematic view of the three-dimensional structure of the rotating member and the upper parts of the application;
[0025] Figure 10 Schematic view of the three-dimensional structure of the shell and the internal parts of the application.
[0026] Label name in the figure: 1, shell, 201, flip cover, 202, stop lever, 301, hollow puncture needle, 302, inlay opening, 401, sampling needle core, 402, sampling opening, 501, rotating member, 502, first identification, 503, second identification, 601, sliding rod, 602, first elastic element, 603, limiting groove, 604, first limiting block, 605, limiting column, 701, sliding ring, 702, button, 703, sliding rod, 704, second elastic element, 705, spring block, 706, second limiting block, 801, piston, 802, connecting frame, 803, moving ring, 804, limiting frame, 805, magnetic block, 806, third elastic element, 807, first air channel, 808, second air channel, 809, adsorption hole, 901, first sealing element, 902, second sealing element, 1001, limiting ring, 1002, fourth elastic element, 1101, limiting frame, 1102, limiting rod, 1103, third limiting block, 1104, extrusion block. DETAILED DESCRIPTION
[0027] The above solutions are further described below in conjunction with specific examples. It should be understood that these examples are used to illustrate the present application and are not intended to limit the scope of the present application. The implementation conditions used in the examples can be further adjusted according to the conditions of specific manufacturers. The implementation conditions not mentioned are usually the conditions in conventional experiments. The shapes and positions of the parts shown in the drawings are only used to facilitate the understanding of the technical solutions proposed in the present application and cannot be used as a factor to limit the present application. In addition, the "fixed connection" described in the present application can be considered as detachable, welded, and threaded connection, etc. in different cases, which cannot be used as a factor to limit the present application.
[0028] Example 1: A medical clinical tumor biopsy sampling device, such as Figures 1-3As shown, it comprises a shell 1, the left side of the rear side of the shell 1 is rotatably connected with a flip 201, the upper side of the flip 201 is rotatably connected with a stop lever 202, the left side of the front side of the shell 1 is provided with a curved lever for limiting cooperation with the stop lever 202, the curved lever is used for limiting the stop lever 202 to prevent the flip 201 from accidentally turning over during sampling, thereby affecting sampling, the left side of the shell 1 is fixedly connected with a hollow puncture needle 301, the shell 1 and the hollow puncture needle 301 are in contact with the flip 201, the front part of the left side of the hollow puncture needle 301 is provided with an inlay opening 302, the hollow puncture needle 301 is slidably and rotatably connected with a sampling needle core 401, the hollow puncture needle 301 is used to wrap the rotating sampling needle core 401, so that the sampling needle core 401 only disturbs the tumor tissue to be sampled, thereby reducing the disturbance to the tumor during sampling and strengthening the protection of the patient, the front part of the left side of the sampling needle core 401 is provided with a sampling port 402, the included angle between the two adjacent surfaces at the edge of the sampling port 402 is an acute angle (i.e. sharp edge), which is used for cutting the tumor tissue, the inlay opening 302 and the sampling port 402 are both provided in an inclined state, the inclined directions of the inlay opening 302 and the sampling port 402 are both gradually inclined downward from left to right (i.e. spiral shape), which is used for applying additional shear stress to the sharp edge of the sampling port 402 while applying pressure stress to the tumor tissue to be cut, thereby improving the smoothness of the sharp edge of the sampling port 402 when cutting the tumor tissue, making the incision of the tumor sample smooth, thereby improving the quality of the tumor sample, and the sampling port 402 is always wrapped by the hollow puncture needle 301 before sampling, thereby preventing the sampling port 402 from scratching the adjacent human tissue during the process of inserting the hollow puncture needle 301 into the patient's body, thereby causing unnecessary harm to the patient, the left side of the shell 1 is rotatably connected with a rotating member 501, the upper part of the right side of the sampling needle core 401 is provided with a first mark 502, the upper part of the left side of the rotating member 501 is provided with a second mark 503, the first mark 502 and the second mark 503 are both black stickers (but not limited to black stickers), the first mark 502 is aligned with the second mark 503, thereby making the sampling port 402 located at the accurate position before sampling, facilitating the smooth progress of subsequent sampling work, the right side of the shell 1 is provided with a power mechanism for rotating the sampling needle core 401.
[0029] As Figure 2 , Figure 4 and Figure 7As shown, the power mechanism includes a sliding rod 601, which is slidingly connected to the right side of the shell 1, and slidingly connected with the rotating member 501 and limitedly matched, and the right side of the sliding rod 601 is provided with a moving block, and the sliding rod 601 is fixedly connected with the shell 1 and provided with a first elastic element 602, which is a spring and used for resetting the sliding rod 601, and the rotating member 501 is provided with a limiting groove 603, which is spiral and gradually decreases from left to right, and used for increasing the rotating speed of the sampling needle core 401 during sampling, so that the sharp edge of the sampling needle core 401 continuously increases the rotating speed before cutting the tumor group, thereby having sufficient energy to cut the tumor tissue, and the right side of the sampling needle core 401 is fixedly connected with a plurality of first limiting blocks 604 in annular array, which are all limitedly matched with the rotating member 501 and used for rotating the sampling needle core 401 to complete sampling, and the upper end of the left side of the sliding rod 601 is fixedly connected with a limiting column 605, which is limitedly matched with the limiting groove 603 and initially located at the right end of the limiting groove 603, and the shell 1 is provided with a limiting assembly for limiting the sliding rod 601.
[0030] As shown in the figure, Figure 4 The limiting assembly includes a sliding ring 701, which is slidingly connected to the right side in the shell 1, and the upper and lower parts of the right side of the shell 1 are slidingly connected with a button 702 and a sliding rod 703, respectively, and the button 702 and the sliding rod 703 are fixedly connected with the sliding ring 701, and the sliding rod 703 is fixedly connected with the shell 1 and provided with a second elastic element 704, which is a spring and used for resetting the sliding rod 703, and the lower part of the inner side of the sliding ring 701 is mounted with a spring block 705, which is composed of a guide shell, a stop block and a spring, the upper side of the stop block is an inclined surface, which gradually inclines downward from left to right, the guide shell is fixedly connected with the sliding ring 701, the stop block is slidingly connected with the guide shell, and the spring is located between the guide shell and the stop block, and the sliding rod 601 is fixedly connected with a second limiting block 706, the lower side of which is an inclined surface, which gradually inclines downward from left to right, and the second limiting block 706 is limitedly matched with the stop block of the spring block 705.
[0031] When the device needs to be used to sample the tumor of a patient, the medical staff rotates the cover 201 clockwise (in the left view direction), and the cover 201 drives the stop lever 202 to rotate clockwise until the cover 201 stops rotating at 90°, at which time the cover 201 is tightly fitted with the hollow puncture needle 301, and then the medical staff rotates the stop lever 202 clockwise until the stop lever 202 stops rotating after being limited by the curved rod of the shell 1, and then the medical staff presses the moving block to the left to move the moving block to the left, and the moving block drives the sliding rod 601 to move to the left, and the sliding rod 601 slides relative to the shell 1, and the sliding rod 601 compresses the first elastic element 602, and the sliding rod 601 drives the limiting column 605 to move to the left, and the limiting column 605 starts to slide and press in the limiting groove 603, and the rotating member 501 starts to rotate counterclockwise (in the left view direction) under the pressing action of the limiting column 605, and the rotating member 501 slides relative to the shell 1, and the rotating member 501 drives the plurality of first limiting blocks 604 to rotate counterclockwise, and the plurality of first limiting blocks 604 jointly drive the sampling needle core 401 to rotate counterclockwise, and the sampling needle core 401 rotates relative to the hollow puncture needle 301, and the inlaying opening 302 and the sampling opening 402 start to interleave each other until the limiting column 605 moves to the left end of the limiting groove 603 and stops moving, at which time the rotating member 501 and the sampling needle core 401 are both rotated counterclockwise by 90°, and the inlaying opening 302 and the sampling opening 402 are completely interleaved, and the sampling opening 402 is completely wrapped by the hollow puncture needle 301.
[0032] In order to reduce the operation steps of the medical staff and improve the efficiency of tumor sampling, the second limiting block 706 is limited by the spring block 705 to limit the sliding rod 601, thereby reducing the additional fixation of the sliding rod 601 by the medical staff in the subsequent sampling process, thereby improving the efficiency during the tumor sampling process. The specific steps are as follows: during the left movement of the sliding rod 601, the sliding rod 601 drives the second limiting block 706 to move to the left, and when the second limiting block 706 moves to the left until the inclined surface thereon contacts the inclined surface on the blocking block of the spring block 705, as the sliding rod 601 continues to move to the left, the second limiting block 706 starts to press the blocking block downward, and the blocking block starts to slide downward along the guide shell, and the blocking block presses the adjacent spring, until the second limiting block 706 moves to the left through the blocking block, and then the blocking block starts to reset under the action of the adjacent spring force, until the spring returns to its original state. The second limiting block 706 is limited by the blocking block, thereby maintaining the compression state of the first elastic element 602, reducing the additional operation steps of the medical staff, and thereby improving the efficiency during the tumor sampling process.
[0033] After stopping the left movement of the sliding rod 601, the medical staff holds the shell 1 close to the tumor area of the patient, and the shell 1 moves with the parts thereon, and when the hollow puncture needle 301 moves to the tumor area (for ease of description, the tumor of the patient is assumed to be locatedFigure 1 For example, the left side of the hollow puncture needle 301), the medical staff moves the shell 1 to the left, and the hollow puncture needle 301 gradually inserts into the patient's tumor. After the hollow puncture needle 301 is inserted into the inside of the tumor to be sampled, the medical staff presses the button 702 downward, the button 702 drives the sliding ring 701 to move downward together, the sliding ring 701 drives the slide rod 703 to move downward together, the sliding ring 701, the button 702 and the slide rod 703 all slide relative to the shell 1, the sliding ring 701 drives the spring block 705 to move downward together, when the stop block moves downward to lose the limiting of the second limiting block 706, the sliding rod 601 starts to move to the right under the action of the first elastic element 602, the sliding rod 601 drives the parts on it to move to the right together, under the extrusion action of the limiting column 605, the rotating part 501 starts to rotate clockwise (left view direction), the rotating part 501 drives the sampling needle core 401 to rotate clockwise to perform the sampling action.
[0034] In order to improve the efficiency in the sampling process and reduce the influence on the tumor body, the sampling needle core 401 rotating in the hollow puncture needle 301 samples the patient's tumor, preventing the conventional sampling device from causing severe disturbance to the patient's tumor during the sampling process, thereby causing the tumor to disperse and spread to other areas of the patient, thereby strengthening the protection of the patient. The specific steps are as follows: during the clockwise rotation of the sampling needle core 401, when the sampling port 402 rotates clockwise to interleave with the inlaid port 302, the tumor tissue in the surrounding area enters the sampling port 402 through the inlaid port 302 due to its own elasticity, and then when the sampling needle core 401 rotates clockwise to the sharp edge of the sampling port 402 contacts the tumor tissue, as the sampling needle core 401 continues to rotate clockwise, the sharp edge of the sampling port 402 starts to cut the tumor tissue in the adjacent area. Since the sampling port 402 is inclined on the sampling needle core 401, the sharp edge of the sampling port 402 will exert pressure stress and shear stress on the adjacent tumor tissue during the clockwise rotation (similar to the process of cutting meat in life), thereby increasing the force exerted on the tumor tissue during the sampling process, and thereby improving the smoothness of the cutting process of the tumor tissue, until the sampling needle core 401 rotates 90° clockwise to complete the cutting. At this time, the sampling port 402 is again completely wrapped by the hollow puncture needle 301.
[0035] Since the sampling needle core 401 only cuts the tumor tissue in the area near the sampling port 402 during the sampling process, i.e. only the tumor area to be sampled is disturbed, the tumor in the remaining positions is not disturbed, thereby avoiding excessive disturbance to the tumor during sampling, increasing the probability of the tumor being disturbed and broken, and even causing the tumor to spread in the patient's body, thereby strengthening the protection of the patient during the sampling process.
[0036] After the sampling is completed, the medical staff moves the shell 1 and the parts thereon to the right, pulls the hollow puncture needle 301 out of the patient's body, and then the medical staff moves the moving block to the right, which drives the sliding rod 601 to move to the right together, and the sliding rod 601 starts to stretch the first elastic element 602. At this time, the sliding rod 601 and the rotating part 501 are in a limiting fit state, that is, the sliding rod 601 drives the rotating part 501 to move to the right together, and the rotating part 501 gradually loses the limiting fit with the plurality of first limiting blocks 604. When the rotating part 501 moves to the right to lose the shielding of the sampling needle core 401 and stops moving, the medical staff then takes out the sampling needle core 401 from the hollow puncture needle 301, takes out the obtained tumor sample from the sampling port 402, and then puts a new sampling needle core 401 into a new hollow puncture needle 301. The new hollow puncture needle 301 is installed on the shell 1, and the first identification 502 and the second identification 503 are aligned. Then the medical staff releases the moving block, and the sliding rod 601 starts to move to the right under the action of the tension of the first elastic element 602. The sliding rod 601 drives the rotating part 501 to move to the left together until the plurality of first limiting blocks 604 are in limiting fit with the rotating part 501 again. Then the device can be stored.
[0037] In order to prevent the tumor tissue from smoothly entering the sampling port 402 during the sampling of the tumor, the present application generates negative pressure by relatively moving the rotating part 501 and the piston 801, and performs negative pressure adsorption on the tumor during the sampling of the tumor, so that the tumor tissue smoothly enters the sampling port 402, and provides sufficient tumor tissue to be cut for the sampling work.
[0038] In example 2, the existing technology related to electromagnetism is used, specifically, when the magnetic induction lines passing through the "coil" change, corresponding induced current is generated in the "coil" (i.e. Lenz's law), which can be expressed as the effect of induced current always resists the cause of induced current. The principle is to use the "coil" when it is close to the magnet. Since the magnetic flux in the "coil" increases, an induced current is generated in the "coil". At this time, the "coil" becomes an electromagnet, and the polarity of the electromagnet is opposite to that of the magnet, so that the two repel each other. In short, it is the law of "coming to refuse to leave".
[0039] Example 2: Based on example 1, as Figures 5-9As shown, the device also includes an adsorption mechanism for adsorbing the target object, the adsorption mechanism is arranged in the left part of the rotating part 501, the adsorption mechanism includes a piston 801, the piston 801 is sealingly and slidingly connected to the rotating part 501, the left end of the sliding rod 601 is rotationally connected with a connecting frame 802, the left side of the connecting frame 802 is fixedly connected with a moving ring 803 which is slidingly connected with the piston 801, the rotating part 501 is fixedly connected with a limiting frame 804 which is slidingly connected with the connecting frame 802, the right side of the piston 801 is fixedly connected with a magnetic block 805 which magnetically cooperates with the moving ring 803, the magnetic block 805 is a magnet, the moving ring 803 is copper, for driving the magnetic block 805 to move differently according to whether the magnetic force appears or not, the magnetic block 805 and the limiting frame 804 are fixedly connected with a third elastic element 806, the third elastic element 806 is a spring, for resetting the magnetic block 805, the sampling needle core 401 is provided with a first air channel 807 which communicates with the rotating part 501, the left side of the sampling needle core 401 is provided with four second air channels 808 which are annularly and equidistantly arranged, the four second air channels 808 all communicate with the first air channel 807, the left side of the sampling needle core 401 is provided with a plurality of adsorption holes 809 which are uniformly arranged, the adsorption holes 809 are used for adsorbing tumor tissues, the plurality of adsorption holes 809 are all opposite to the sampling port 402, the plurality of adsorption holes 809 respectively communicate with adjacent second air channels 808, the rotating part 501 is provided with a sealing assembly which is used for sealing the rotating part 501 itself, the piston 801 moves to the right and relatively slides with the rotating part 501, so that a negative pressure environment is formed in the first air channel 807, thereby the plurality of adsorption holes 809 generate suction force to adsorb adjacent tumor tissues, so that the tumor tissues smoothly enter the sampling port 402, and sufficient tumor tissues are provided for subsequent sampling.
[0040] As shown in Figure 7 and Figure 9 , the sealing assembly includes a first sealing member 901, the first sealing member 901 is fixedly connected to the right side of the sampling needle core 401, the left side of the rotating part 501 is fixedly connected with a second sealing member 902 which is in contact with the first sealing member 901, the first sealing member 901 and the second sealing member 902 are both made of elastic rubber material, and the outer shape of the first sealing member 901 and the inner shape of the second sealing member 902 are both "circular truncated cone shape" for increasing the contact area between them, the housing 1 is slidingly connected with a limiting ring 1001 which is rotationally connected with the rotating part 501, the limiting ring 1001 and the housing 1 are fixedly connected with two fourth elastic elements 1002 which are arranged in an upper and lower mirror image manner, the fourth elastic elements 1002 are tension springs, and the fourth elastic elements 1002 are initially in a stretched state, for continuously exerting a leftward force on the limiting ring 1001, the housing 1 is provided with a blocking assembly which is used for limiting the limiting ring 1001.
[0041] As shown in Figure 10As shown, the blocking assembly includes two limiting frames 1101 arranged in mirror image, both of which are fixedly connected in the shell 1, the limiting frame 1101 is slidingly connected with a limiting rod 1102, the limiting rod 1102 and the adjacent limiting frame 1101 are fixedly connected with a spring, which is used for resetting the adjacent limiting rod 1102, the left end of the limiting rod 1102 is fixedly connected with a third limiting block 1103, both of which are limited with the limiting ring 1001, thereby preventing the rotating part 501 from moving due to the friction of the piston 801 to the right during sampling, causing the negative pressure environment of the first air duct 807 to be affected and losing the adsorption of the tumor tissue, so that the several adsorption holes 809 can smoothly adsorb the tumor tissue of the adjacent area, the left side of the sliding rod 601 is fixedly connected with a pressing block 1104, the right part of the pressing block 1104 is provided with an inclined surface, the distance between the inclined surface and the left end surface of the sliding rod 601 gradually decreases from right to left, both of the limiting rods 1102 are limited with the inclined surface of the pressing block 1104, the two limiting rods 1102 are pressed by the pressing block 1104, so that the two limiting rods 1102 move backward, thereby facilitating the subsequent removal of the tumor sample.
[0042] In order to avoid the tumor sample being too small or sampling failure due to the tumor tissue being difficult to enter the sampling port 402 by its own elasticity, the piston 801 is moved to the right to generate negative pressure in the first air channel 807, so that the adsorption holes 809 adsorb the tumor tissue in the vicinity, thereby ensuring the tumor tissue to enter the sampling port 402 smoothly, and fully sampling the tumor tissue, and further improving the sampling effect of the tumor tissue. The specific steps are as follows: in the process of the sliding rod 601 moving to the right, the sliding rod 601 drives the connecting frame 802 to move to the right together, the connecting frame 802 slides relative to the limiting frame 804, and the connecting frame 802 drives the moving ring 803 to move to the right together. In the process of the moving ring 803 moving to the right, the magnetic flux in the moving ring 803 gradually increases, that is, an induced current appears in the moving ring 803. According to the law of electromagnetic induction, the moving ring 803 at this time is equivalent to a magnet, and the polar direction is opposite to that of the magnetic block 805, that is, the magnetic block 805 starts to be subjected to a magnetic force to the right. Then the magnetic block 805 starts to move to the right, and the magnetic block 805 drives the piston 801 to move to the right together. The piston 801 slides relative to the rotating part 501, and the magnetic block 805 compresses the third elastic element 806. Then the piston 801 extracts the air in the first air channel 807, and negative pressure is formed in the first air channel 807, that is, suction exists at the adsorption holes 809 opposite to the axis of the sampling needle core 401. Then when the sampling port 402 rotates clockwise to intersect with the inlaid port 302, the tumor tissue in the vicinity is subjected to the suction of the negative pressure and starts to enter the sampling port 402, thereby providing sufficient tumor tissue for subsequent cutting, and further improving the success rate and sampling quality of the tumor sampling. When the sampling is completed, the moving ring 803 stops moving to the right, and then the magnetic block 805 starts to move to the left under the action of the elasticity of the third elastic element 806. The negative pressure environment in the first air channel 807 gradually disappears, and the suction of the adsorption holes 809 gradually disappears, that is, the adsorption of the tumor sample is lost, thereby facilitating the subsequent removal of the tumor sample.
[0043] In order to ensure the stability of the negative pressure in the first air channel 807, thereby stabilizing the suction force at each adsorption hole 809, the fourth elastic element 1002 generates a pulling force on the limiting ring 1001, and the third limiting block 1103 limits the limiting ring 1001 to the right, so that the rotating part 501 has a tendency to continuously move to the left, thereby making the second sealing part 902 tightly fit with the first sealing part 901, ensuring the sealing of the first air channel 807, and further improving the success rate of sampling the tumor. The specific steps are as follows: during the movement of the sliding rod 601 to the left and the clockwise rotation of the rotating part 501, the rotating part 501 and the limiting ring 1001 rotate relative to each other, the two fourth elastic elements 1002 pull the limiting ring 1001 to the left, the limiting ring 1001 presses the rotating part 501 to the left, the rotating part 501 presses the second sealing part 902 to the left, the second sealing part 902 presses the first sealing part 901 to the left, and the first sealing part 901 and the second sealing part 902 are deformed and tightly contact each other to seal, while the two third limiting blocks 1103 limit the limiting ring 1001, avoiding the movement of the rotating part 501 to the right due to friction during the movement of the piston 801 to the right, thereby causing the first air channel 807 to lose its adsorption of the tumor tissue. In this way, the plurality of adsorption holes 809 successfully adsorb the tumor tissue in the adjacent region, and the tumor tissue in the region to be cut enters the sampling port 402 smoothly, thereby improving the success rate and quality of sampling.
[0044] When the sampling is completed and the sliding rod 601 moves to the right, the sliding rod 601 drives the pressing block 1104 to move to the right together. When the pressing block 1104 moves to the right until the inclined surface thereof contacts the two limiting rods 1102, as the sliding rod 601 continues to move to the right, the inclined surface of the pressing block 1104 begins to press the two limiting rods 1102, the two limiting rods 1102 begin to move away, the limiting rod 1102 begins to compress the adjacent spring, the limiting rod 1102 slides relative to the adjacent limiting frame 1101, the limiting rod 1102 drives the adjacent third limiting block 1103 to move together, until the two pressing blocks 1104 move away from the limiting ring 1001, at which time the sampling needle core 401 stops rotating clockwise and completes sampling.
[0045] In the process of taking out the tumor sample, the sliding rod 601 moves to the right, the sliding rod 601 drives the rotating part 501 to move to the right, the rotating part 501 drives the limiting ring 1001 to move to the right, the limiting ring 1001 stretches the two fourth elastic elements 1002, then the medical staff can take out the sample, when the medical staff resets the device, in the process of the sliding rod 601 moving to the left, the limiting ring 1001 starts to move to the left under the action of the tension of the two fourth elastic elements 1002, the limiting ring 1001 drives the rotating part 501 to move to the left, the sliding rod 601 drives the extrusion block 1104 to move to the left, in the process, the rotating part 501 keeps relatively stationary with the sliding rod 601, until the rotating part 501 moves to the initial position, the inclined surface on the extrusion block 1104 gradually loses the extrusion on the two limiting rods 1102, the two limiting rods 1102 start to move oppositely under the action of the adjacent spring elasticity, the limiting rod 1102 drives the adjacent third limiting block 1103 to move, until the two third limiting blocks 1103 both limit the limiting ring 1001 again.
[0046] Finally, it should be noted that: the above only for the preferred embodiments of the application, and not for limiting the application, although the application is described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features, any modification, equivalent replacement, improvement, etc. within the spirit and principles of the application, should be included in the protection scope of the application.
Claims
1. A tumor biopsy sampling device for clinical medical use, comprising a housing (1), a flip cover (201) rotatably connected to one side of the housing (1), a stop bar (202) rotatably connected to the flip cover (201), a bent rod provided on one side of the housing (1), the bent rod being in a limiting fit with the stop bar (202), a hollow puncture needle (301) fixedly connected to the side of the housing (1) near the flip cover (201), both the housing (1) and the hollow puncture needle (301) being in contact with the flip cover (201), and an insert (302) provided on the side of the hollow puncture needle (301) away from the housing (1), characterized in that, Also include a sampling needle core (401), the sampling needle core (401) is slidingly and rotatably connected in the hollow puncture needle (301), the sampling needle core (401) is provided with a sampling port (402) on the side close to the inlay port (302), the shell (1) is rotatably connected with a rotating part (501), the sampling needle core (401) is provided with a first mark (502) on the side close to the rotating part (501), the rotating part (501) is provided with a second mark (503) on the side close to the hollow puncture needle (301), the shell (1) is provided with a power mechanism for rotating the sampling needle core (401); The power mechanism comprises a sliding rod (601), the sliding rod (601) is limitingly and slidingly connected to the side of the shell (1) away from the hollow puncture needle (301), the sliding rod (601) is slidingly connected with the rotating part (501) and is limitingly matched, the side of the sliding rod (601) away from the rotating part (501) is provided with a moving block, the first elastic element (602) is fixedly connected between the sliding rod (601) and the shell (1), the rotating part (501) is provided with a limiting groove (603), the sampling needle core (401) is fixedly connected with a first limiting block (604) of annular array on the side close to the rotating part (501), the first limiting block (604) of annular array is limitingly matched with the rotating part (501), one end of the sliding rod (601) close to the rotating part (501) is fixedly connected with a limiting column (605), the limiting column (605) is limitingly matched with the limiting groove (603), the shell (1) is provided with a limiting assembly for limiting the sliding rod (601). The limiting groove (603) is spiral, and the spiral pitch of the limiting groove (603) gradually changes from the side close to the hollow puncture needle (301) to the other side, for the hollow puncture needle (301) to rotate with gradually changing speed.
2. The medical clinical tumor biopsy sampling device according to claim 1, wherein, The inlay port (302) and the sampling port (402) are respectively deflected to one side along the outer wall of the hollow puncture needle (301) and the outer wall of the sampling needle core (401), for the sharp edge of the sampling port (402) to apply additional shear stress to the target.
3. The medical clinical tumor biopsy sampling device according to claim 2, wherein, The limiting assembly comprises a sliding ring (701) which is slidingly connected to the side of the shell (1) away from the hollow puncture needle (301), the shell (1) is slidingly connected with a button (702) and a sliding rod (703), the button (702) and the sliding rod (703) are fixedly connected with the sliding ring (701), the second elastic element (704) is fixedly connected between the sliding rod (703) and the shell (1), the side of the sliding ring (701) close to the sliding rod (601) is provided with a spring block (705), the sliding rod (601) is fixedly connected with a second limiting block (706), the second limiting block (706) is limitingly matched with the spring block (705).
4. The medical clinical tumor biopsy sampling device according to claim 3, wherein, Further comprising an adsorption mechanism for adsorbing the target object, the adsorption mechanism is arranged on the rotating piece (501), the adsorption mechanism comprises a piston (801), the piston (801) is sealingly and slidingly connected to the rotating piece (501), one end of the sliding rod (601) close to the piston (801) is rotatably connected with a connecting frame (802), the side of the connecting frame (802) away from the sliding rod (601) is fixedly connected with a moving ring (803), the moving ring (803) is slidingly connected with the piston (801), the rotating piece (501) is fixedly connected with a limiting frame (804) inside, the limiting frame (804) is slidingly connected with the connecting frame (802), the side of the piston (801) close to the limiting frame (804) is fixedly connected with a magnetic block (805), the magnetic block (805) is magnetically matched with the moving ring (803), the third elastic element (806) is fixedly connected between the magnetic block (805) and the limiting frame (804), the sampling needle core (401) is provided with a first air channel (807) inside, the first air channel (807) is communicated with the rotating piece (501), the sampling needle core (401) is provided with equidistantly arranged second air channels (808) on the side away from the shell (1), the equidistantly arranged second air channels (808) are all communicated with the first air channel (807), the sampling needle core (401) is provided with uniformly arranged adsorption holes (809) on the side away from the shell (1), the adsorption holes (809) are located in the sampling port (402), the uniformly arranged adsorption holes (809) are respectively communicated with adjacent second air channels (808), the rotating piece (501) is provided with a sealing assembly for sealing itself.
5. The medical clinical tumor biopsy sampling device according to claim 4, wherein, The moving ring (803) is made of copper, which is used for driving the magnetic block (805) to move differently according to whether the magnetic force appears.
6. The medical clinical tumor biopsy sampling device according to claim 5, wherein, The sealing assembly comprises a first sealing piece (901) fixedly connected to the sampling needle core (401) near one side of the rotating piece (501), one side of the rotating piece (501) near the first sealing piece (901) is fixedly connected with a second sealing piece (902), and the second sealing piece (902) is in contact with the first sealing piece (901).
7. The medical clinical tumor biopsy sampling device of claim 6, wherein, The shell (1) is slidably connected with a limiting ring (1001), the limiting ring (1001) is rotationally connected with the rotating piece (501), and the limiting ring (1001) and the shell (1) are fixedly connected with mirror image arranged fourth elastic elements (1002), and the shell (1) is provided with a blocking assembly for limiting the limiting ring (1001).
8. The medical clinical tumor biopsy sampling device according to claim 7, wherein, The blocking assembly comprises mirror image arranged limiting frames (1101), the limiting frames (1101) are fixedly connected in the shell (1), the limiting frames (1101) are slidably connected with limiting rods (1102), the limiting rods (1102) and the adjacent limiting frames (1101) are fixedly connected with springs, one end of the limiting rod (1102) near the limiting ring (1001) is fixedly connected with a third limiting block (1103), the third limiting blocks (1103) are in limiting cooperation with the limiting ring (1001), and one side of the sliding rod (601) near the rotating piece (501) is fixedly connected with an extrusion block (1104).
Citation Information
Patent Citations
Pathological specimen sampler for pathological diagnosis
CN116509464A
Tumor biopsy puncture needle
CN209751112U