An acaricide, its preparation method and application

Abstract

The present invention provides an anti-mite agent, a preparation method thereof and an application, relating to the technical field of bactericidal and pesticidal agents. In terms of mass percentage content, the anti-mite agent provided by the present invention comprises 4-6% of mustard oil, 4-6% of clove oil or carvacrol, 1-2% of a preservative, and the balance of a base material. The present invention combines the use of mustard oil and clove oil (or carvacrol), combines the rapid volatilization of the smell of mustard oil with the slow volatilization of the smell of clove oil (or carvacrol), gives play to their respective advantages, and plays a role in fumigating and killing mites. The anti-mite agent of the present invention can kill mites inside a household mattress, and does not use toxic products such as chemicals and pesticides, so that people's physical contact with the mattress is both safe and free of mites, protecting people's physical health. The mattress has been tested and meets the functional characteristic standard of the GB / T 1952.2-2023 Soft Furniture-Spring Soft Mattress standard, and the mite inhibition rate is over 60%.

Description

Technical Field

[0001] The present invention relates to the technical field of bactericidal and insecticidal agents, and particularly to an acaricide and its preparation method and application. Background Art

[0002] At present, mattresses have become popular in thousands of households. Due to human metabolism, a large amount of old skin debris is discharged every day. At a suitable room temperature, microorganisms such as mites feed on the old skin debris and reproduce rapidly, and leave secretions invisible to the naked eye, which are spread through contact and air. If people inhale the secretions of mites, it will cause diseases such as asthma and rhinitis. Moreover, the secretions, metabolites and dead bodies of mites are strong allergens, which can also cause allergic dermatitis, allergic bronchitis, etc. Therefore, with the continuous improvement of people's material living standards, people pay more attention to the home environment. In particular, bedding that can prevent the breeding and killing of mites is favored by people. Therefore, it is urgent to prepare an acaricide. Summary of the Invention

[0003] The purpose of the present invention is to provide an acaricide and its preparation method and application. The acaricide provided by the present invention can effectively fumigate and kill mites and protect people's physical health.

[0004] In order to achieve the above-mentioned invention purpose, the present invention provides the following technical solutions:

[0005] The present invention provides an acaricide which, in terms of mass percentage content, comprises the following components: 4-6% of mustard oil, 4-6% of clove oil or carvacrol, 1-2% of a preservative, and the balance of a base material.

[0006] Preferably, the preservative comprises sodium benzoate and / or potassium sorbate.

[0007] Preferably, the base material comprises kaolin and / or bentonite.

[0008] Preferably, the dosage form of the acaricide is a tablet or a powder.

[0009] Preferably, when it is a tablet, the acaricide further comprises 5-10% of a solid glue.

[0010] Preferably, the solid glue comprises polyvinylpyrrolidone.

[0011] The present invention provides a preparation method of the acaricide according to the above-mentioned scheme, which comprises the following steps: mixing each component to obtain the acaricide.

[0012] Preferably, when the acaricide is a tablet, after the mixing, it further comprises pressing the obtained mixture into tablets.

[0013] The present invention provides the application of the acaricide described in the above solution or the acaricide prepared by the preparation method described in the above solution in preventing mites in household articles.

[0014] Preferably, the household articles include mattresses.

[0015] The present invention provides an acaricide which, by mass percentage, comprises the following components: 4-6% of mustard oil, 4-6% of clove oil or carvacrol, 1-2% of preservative and the balance of base material.

[0016] The special smell of mustard oil is the natural enemy of mites. Through laboratory tests, when 1 gram of mustard oil emits its smell, more than 90% of adult mites in a sealed volume of 0.5 cubic meters communicating with the air can be fumigated and killed within 48 hours. The smells of clove oil and carvacrol also have the effect of fumigating and killing mites, but during fumigation, the effect is slow, and the length of time for the volatile smell is more than 5 times that of mustard oil.

[0017] The present invention combines mustard oil and clove oil (or carvacrol) for use, combining the rapid volatile smell of mustard oil with the slow volatile smell of clove oil (or carvacrol), giving full play to their respective advantages and playing a role in fumigating and killing mites. Moreover, mustard oil is a raw material for making mustard paste and can be edible, belonging to the food grade; clove oil is a raw material for making essence and skin care essential oil used in massage; carvacrol can be used as edible essence. The product has been tested by the Comparative Medicine Laboratory of Guangdong Provincial Center for Medical Laboratory Animals, and the toxicity classification is actually non-toxic (see Figure 3 ).

[0018] The acaricide of the present invention can kill mites inside household mattresses without using toxic products such as chemicals and pesticides, making it safe for people to come into contact with the mattresses and free of mites, thus protecting people's physical health. Description of the Drawings

[0019] Figures 1 - 2 It is the mite prevention detection report issued by the National Furniture Product Quality Supervision and Inspection Center (Guangzhou);

[0020] Figure 3 It is the detection report issued by the Comparative Medicine Laboratory of Guangdong Provincial Center for Medical Laboratory Animals for the acaricide of the present invention. Detailed Embodiments

[0021] The present invention provides an acaricide which, by mass percentage, comprises the following components: 4-6% of mustard oil, 4-6% of clove oil or carvacrol, 1-2% of preservative and the balance of base material.

[0022] In the present invention, unless otherwise specified, the raw materials used are all well-known commercially available products in the art.

[0023] In terms of mass percentage, the acaricide provided by the present invention includes 4-6% of mustard oil, specifically it can be 4%, 4.5%, 5%, 5.5% or 6%, and there is no need to list them all here. The special smell of mustard oil is the natural enemy of mites. Through laboratory tests, taking 1 gram of mustard oil, the emitted smell can fumigate and kill more than 90% of adult mites in a closed air volume of 0.5 cubic meters within 48 hours.

[0024] In terms of mass percentage, the acaricide provided by the present invention includes 4-6% of clove oil or carvacrol, specifically it can be 4%, 4.5%, 5%, 5.5% or 6%, and there is no need to list them all here. In the present invention, the smells of clove oil and carvacrol also have the effect of fumigating and killing mites, but during fumigation, the effect is slow, and the length of time for the volatile smell is more than 5 times that of mustard oil.

[0025] The present invention combines mustard oil and clove oil (or carvacrol) for use, combines the rapid volatile smell of mustard oil and the slow volatile smell of clove oil (or carvacrol), gives full play to their respective advantages, and plays a role in fumigating and killing mites.

[0026] In terms of mass percentage, the acaricide provided by the present invention includes 1-2% of preservative, specifically it can be 1%, 1.2%, 1.4%, 1.6%, 1.8% or 2%, and there is no need to list them all here. In the present invention, the preservative preferably includes sodium benzoate and / or potassium sorbate.

[0027] The acaricide provided by the present invention includes the balance of base material; the base material preferably includes kaolin and / or bentonite.

[0028] In the present invention, the dosage form of the acaricide is preferably a tablet or a powder. The present invention has no special requirements for the size of the tablet, and those skilled in the art can choose according to actual needs. In the embodiments of the present invention, the diameter of the tablet is 2.3 cm, the thickness is 1.1 cm, and the single tablet weighs 6 g.

[0029] In the present invention, when it is a tablet, the acaricide preferably further includes 5-10% of solid glue, preferably 6-9%, and more preferably 7-8%. In the present invention, the solid glue preferably includes polyvinylpyrrolidone.

[0030] In the present invention, the pH value of the acaricide is preferably 5-7.

[0031] The present invention provides a preparation method of the acaricide according to the above scheme, including the following steps: mixing each component to obtain the acaricide.

[0032] The present invention has no special requirements for the mixing process, and it is only necessary to mix each component evenly.

[0033] In the present invention, when the acaricide further comprises a solid glue, the mixing preferably comprises: first mixing mustard oil, clove oil (or carvacrol), a preservative and a base material, so that the mustard oil and the clove oil (or carvacrol) are fully absorbed by kaolin, and then adding the solid glue and stirring evenly.

[0034] In the present invention, when the acaricide is in tablet form, after the mixing is completed, the present invention preferably presses the obtained mixture into tablets. The present invention has no special requirements for the process of pressing into tablets, and a tablet pressing process well-known in the art can be adopted.

[0035] After obtaining the acaricide, the present invention preferably seals and packages it with an airtight plastic film.

[0036] The present invention provides the application of the acaricide described in the above solution or the acaricide prepared by the preparation method described in the above solution in the prevention of mites in household items.

[0037] In the present invention, the household items preferably include mattresses.

[0038] When the acaricide is used for preventing mites in mattresses, the mite prevention method preferably comprises the following steps: pricking several small holes in the packaging of the acaricide with a needle, and placing the acaricide in the ventilation holes of the mattress. The present invention preferably places the acaricide in 4 ventilation holes on both sides of the mattress. When the smell of the acaricide spreads out, the effect of fumigating and killing adult mites in the mattress can be achieved.

[0039] The following examples are used to illustrate in detail the acaricide provided by the present invention, its preparation method and application, but they should not be construed as limiting the protection scope of the present invention.

[0040] Example 1

[0041] Mustard oil, clove oil, sodium benzoate, kaolin (base material), and polyvinylpyrrolidone (solid glue) were purchased from the market and formulated according to the weight percentage: 5% mustard oil, 5% clove oil, 1% sodium benzoate, and 82% kaolin. They were mixed and stirred evenly to make the mustard oil and clove oil fully absorbed by the kaolin, and then 7% of polyvinylpyrrolidone was added and stirred evenly to prepare 1000 grams of the agent. The agent was pressed into tablets with a diameter of 2.3 cm, a thickness of 1.1 cm, and a weight of about 6 grams using a pharmaceutical tablet press. 1000 grams could produce 166 tablets.

[0042] Finally, it is sealed and packaged with an airtight plastic film. Four tablets are taken and installed in the four ventilation holes on both sides of the mattress, with one tablet installed in each ventilation hole. When in use, use a needle to pierce several small holes in the plastic film packaging in the ventilation holes of the mattress to allow the mustard oil and clove oil odors of the tablets to slowly volatilize, so as to fumigate and kill the adult mites in the mattress. After testing, the mite inhibition rate is 73.1% (the time required for the mite inhibition rate to reach 73.1% is 2 - 3 days), which meets the functional characteristic standard of the GB / T1952.2-2023 Soft Furniture Spring Soft Mattress Standard, and the mite inhibition rate reaches more than 60% (see Figures 1 - 2 : Inspection Report of the National Furniture Product Quality Supervision and Inspection Center (Guangzhou) on February 4, 2024), and after the mite inhibition rate reaches more than 60%, it can maintain for a relatively long time, and the validity period is 10 days.

[0043] Comparative Example 1

[0044] The difference from Example 1 is that: 8% mustard oil and 2% clove oil, and the others remain unchanged. The results show that the anti-mite agent in Comparative Example 1 has a fast volatilization time and good mite killing effect, but the drug efficacy also slows down quickly, and the validity period is shortened by 5 days compared with Example 1.

[0045] Comparative Example 2

[0046] The difference from Example 1 is that: 2% mustard oil and 8% clove oil, and the others remain unchanged. According to the experimental results, under the same conditions, to achieve a mite killing rate of 60%, the time needs to be extended to 15 days.

[0047] Example 2

[0048] Mustard oil, carvacrol, potassium sorbate, and bentonite (base material) are purchased on the market and formulated by weight percentage: 5% mustard oil, 5% carvacrol, 1% potassium sorbate, and 89% bentonite. They are mixed and stirred evenly to prepare 1000 grams of the agent, which is packaged into airtight 6-gram powder sachets with an airtight plastic film. 1000 grams of the agent can produce 166 sachets, and then they are installed in the four ventilation holes on both sides of the mattress, with 6 grams / bag installed in each ventilation hole. When in use, use a needle to pierce several small holes in the plastic film packaging in the ventilation holes of the mattress to allow the mustard oil and carvacrol odors to slowly volatilize, so as to fumigate and kill the adult mites in the mattress, and the mite inhibition rate is 70%.

[0049] The above are only the preferred embodiments of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. An acaricide, characterized in that, By mass percentage, it consists of the following components: 4 - 6% of mustard oil, 4 - 6% of clove oil, 1 - 2% of preservative, 5 - 10% of solid glue and the balance of base material; the dosage form of the acaricide is tablet; the base material is kaolin and / or bentonite; the solid glue is polyvinylpyrrolidone.

2. The acaricide according to claim 1, characterized in that, The preservative includes sodium benzoate and / or potassium sorbate.

3. The preparation method of the acaricide according to any one of claims 1 to 2, comprising the following steps: Mix the components, and press the obtained mixture into tablets to obtain the acaricide.

4. Application of the acaricide according to any one of claims 1 - 2 or the acaricide prepared by the preparation method according to claim 3 in preventing mites in household items.

5. The application according to claim 4, characterized in that The household items include mattresses.

Images