A firming and anti-early aging composition and its application

Abstract

The present invention discloses a firming and anti-aging composition and its application, belonging to the technical field of cosmetics; the composition is prepared from the following raw materials in parts by mass: 6-15 parts of Agrimonia pilosa Ledeb. extract, 6-15 parts of Lycium barbarum extract, 5-12 parts of Ligusticum chuanxiong extract, 6-10 parts of resveratrol, 6-10 parts of longan pulp extract, 4-8 parts of Polygonum cuspidatum extract, 4-8 parts of Rubus idaeus extract, 0.5-15 parts of polyethylene glycol-4000, 1-7 parts of glycerol, 1-7 parts of butanediol, and 30-80 parts of water; the composition can be used as an additive to prepare cosmetics with anti-wrinkle repair, moisturizing, and improving skin elasticity. The ingredients are natural and mild in nature, can significantly enhance skin elasticity, and can effectively combat early aging.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and particularly relates to a firming and anti-early aging composition and its application. Background Art

[0002] Premature aging begins at the age of 25, and the skin will gradually enter the state of natural aging. After women reach the age of 25, skin functions begin to decline, and collagen is also gradually lost. The main characteristics of premature skin aging include increased fine lines, yellowish face, dull skin tone, difficult-to-remove acne marks, enlarged pores, skin relaxation, and sagging apple muscles. Skin aging is mainly divided into two types: one is endogenous aging, also known as natural aging, which is mainly affected by genetic factors and is a natural progressive aging process; the other is exogenous aging caused by external environmental factors such as ultraviolet radiation, smoking, gravity, and chemicals. Among them, more than 80% of facial skin aging is due to ultraviolet radiation, so it is also called photoaging. The characteristics of this type of skin aging are rough skin texture, dull skin tone, pigmentation, and loss of skin elasticity.

[0003] "Anti-" means to retain the collagen in the skin before the signs of skin aging appear, so as to delay the aging phenomenon of our skin. Anti-early aging is to delay skin aging. In fact, it is still anti-aging in essence, and the principle has not changed, but it emphasizes "early" more. The earlier the anti-aging, the better the effect. At present, there are a wide variety of anti-aging products on the market, but the safety and effectiveness of the ingredients contained are issues that consumers continue to pay attention to. Generally, the products have the problems of numerous ingredients and strong irritation, the user experience satisfaction is not high, and the effect after use is not very obvious. Summary of the Invention

[0004] The purpose of the present invention is to provide a firming and anti-early aging composition, its preparation method and application. The firming and anti-early aging composition provided by the present invention has natural ingredients, mild properties, good moisturizing effect, can enhance skin elasticity, and can effectively fight against premature aging.

[0005] In the first aspect, the present invention provides a firming and anti-early aging composition, which is prepared from the following raw materials in parts by mass:

[0006] 6-15 parts of Agrimonia pilosa Ledeb. extract, 6-15 parts of Lycium barbarum L. extract, 5-12 parts of Ligusticum chuanxiong Hort. extract, 6-10 parts of resveratrol, 6-10 parts of longan pulp extract, 4-8 parts of Polygonum cuspidatum Sieb. et Zucc. extract, 4-8 parts of Rubus idaeus L. extract, 0.5-15 parts of polyethylene glycol-400, 1-7 parts of glycerol, 1-7 parts of butanediol, and 30-80 parts of water.

[0007] Further, the firming and anti-early aging composition further includes 6-10 parts of garlic extract.

[0008] Optionally, the mass ratio of Agrimonia pilosa Ledeb. extract: Lycium barbarum extract: Ligusticum chuanxiong extract is (1-2):(1-2):(0.5-3).

[0009] Optionally, the firming and anti-aging composition is prepared from the following raw materials in parts by mass:

[0010] 8-10 parts of Agrimonia pilosa Ledeb. extract, 8-10 parts of Lycium barbarum extract, 6-8 parts of Ligusticum chuanxiong extract, 7-9 parts of resveratrol, 6-8 parts of longan pulp extract, 6-8 parts of Polygonum cuspidatum extract, 6-8 parts of Rubus idaeus extract, 8-10 parts of garlic extract.

[0011] Optionally, the preparation method of the Agrimonia pilosa Ledeb. extract comprises the following steps:

[0012] Step 1: Take fresh Agrimonia pilosa Ledeb. leaves, wash, cut into sections, dry at 50-70 °C, crush with a pulverizer, and sieve through 100-400 meshes to obtain Agrimonia pilosa Ledeb. leaf powder;

[0013] Step 2: Weigh an appropriate amount of Agrimonia pilosa Ledeb. leaf powder, add a solvent with an appropriate solid-liquid ratio for extraction, the temperature is 45-80 °C, extract 2-4 times, 1-3 h each time. After extraction is completed, centrifuge at a speed of 4000 r / min for 5 min, collect and combine the supernatant, and then concentrate the supernatant under reduced pressure to 1-5 times the weight of the Agrimonia pilosa Ledeb. leaf powder to obtain the concentrated Agrimonia pilosa Ledeb. leaf liquid;

[0014] Step 3: Then add an appropriate amount of stabilizer for re-dissolution, add activated carbon and let stand for 4-8 h, and filter through a membrane to obtain the Agrimonia pilosa Ledeb. leaf extract.

[0015] Preferably, the solid-liquid ratio in Step 2 is 1:(6-25), the extraction solvent is ethanol or its aqueous ethanol solution, and the extraction method is heating and stirring extraction or ultrasonic extraction.

[0016] Preferably, the concentrated Agrimonia pilosa Ledeb. leaf liquid in Step 2 also undergoes one or more steps of alcohol precipitation or resin purification before entering Step 3.

[0017] Preferably, the stabilizer in Step 3 is one or more of glycerol, butanediol, and propylene glycol.

[0018] Preferably, the process of alcohol precipitation is to add 2-4 times of absolute ethanol, let stand for 8-16 h, collect the precipitated part, dissolve it in water, and then concentrate under reduced pressure.

[0019] Preferably, the process of resin purification is to add the concentrated liquid to the resin, wash with deionized water until transparent, and then elute with an aqueous ethanol solution, and collect the eluate.

[0020] In a second aspect, the present invention provides the use of the above-mentioned firming and anti-aging composition in the preparation of a cosmetic having anti-wrinkle and moisturizing effects and improving skin elasticity, and a topical skin preparation having anti-wrinkle and moisturizing effects and improving skin elasticity prepared by adding conventional pharmaceutical or cosmetic excipients or auxiliary components.

[0021] Optionally, the cosmetic includes one or more of lotion, cream, essence, gel, primer, sunscreen, and foundation.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] The firming and anti-aging composition provided by the present invention has natural ingredients, mild properties, significant moisturizing effects, can enhance skin elasticity, repair the skin, and improve the symptoms of premature aging.

[0024] The firming and anti-aging composition provided by the present invention has the advantages of simple preparation, remarkable effects, being suitable for large-scale production, being pure natural, non-irritating, safe and non-toxic, can meet the requirements of safe skin care, has good anti-wrinkle effects, and has good promotion prospects and a broad application market. Detailed Embodiments

[0025] The following combines the detailed embodiments to further elaborate on the claims of the present invention, but does not constitute any limitation to the present invention. Any limited modifications made by anyone within the scope of the claims of the present invention are still within the scope of the claims of the present invention.

[0026] The raw materials used in the detailed embodiments of the present invention are sourced as follows: The wolfberry extract is purchased from Ningxia Vanilla Biotechnology Co., Ltd. The chuanxiong extract is purchased from Hebei Hongtao Biotechnology Co., Ltd. Resveratrol is purchased from Jiangsu Caiwei Biotechnology Co., Ltd. The longan pulp extract is purchased from Xi'an Allbio Biotechnology Co., Ltd. The polygonum cuspidatum extract is purchased from Guangdong Osmann Biotechnology Co., Ltd. The raspberry extract is purchased from Shaanxi Junhe Biotechnology Co., Ltd.

[0027] Example 1

[0028] The present invention provides a firming and anti-aging composition prepared from the following raw materials in parts by mass:

[0029] 10 parts of agrimony extract, 10 parts of wolfberry extract, 8 parts of chuanxiong extract, 8 parts of resveratrol, 9 parts of longan pulp extract, 6 parts of polygonum cuspidatum extract, 6 parts of raspberry extract, 2 parts of polyethylene glycol-400, 3 parts of glycerol, 3 parts of butanediol, and 45 parts of water.

[0030] Example 2

[0031] 15 parts of Agrimonia pilosa Ledeb. extract, 15 parts of Lycium barbarum extract, 12 parts of Ligusticum wallichii extract, 10 parts of resveratrol, 10 parts of longan pulp extract, 8 parts of Polygonum cuspidatum extract, 8 parts of Rubus idaeus extract, 2 parts of polyethylene glycol - 400, 4 parts of glycerol, 4 parts of butanediol and 50 parts of water.

[0032] Example 3

[0033] 6 parts of Agrimonia pilosa Ledeb. extract, 6 parts of Lycium barbarum extract, 5 parts of Ligusticum wallichii extract, 6 parts of resveratrol, 6 parts of longan pulp extract, 4 parts of Polygonum cuspidatum extract, 4 parts of Rubus idaeus extract, 3 parts of polyethylene glycol - 400, 3 parts of glycerol, 4 parts of butanediol and 40 parts of water.

[0034] Example 4

[0035] 8 parts of Agrimonia pilosa Ledeb. extract, 10 parts of Lycium barbarum extract, 10 parts of Ligusticum wallichii extract, 10 parts of resveratrol, 10 parts of longan pulp extract, 8 parts of Polygonum cuspidatum extract, 8 parts of Rubus idaeus extract, 5 parts of polyethylene glycol - 400, 2 parts of glycerol, 5 parts of butanediol and 50 parts of water.

[0036] Example 5

[0037] 12 parts of Agrimonia pilosa Ledeb. extract, 8 parts of Lycium barbarum extract, 8 parts of Ligusticum wallichii extract, 9 parts of resveratrol, 7 parts of longan pulp extract, 5 parts of Polygonum cuspidatum extract, 6 parts of Rubus idaeus extract, 3 parts of polyethylene glycol - 400, 3 parts of glycerol, 5 parts of butanediol and 50 parts of water.

[0038] Example 6

[0039] 8 parts of Agrimonia pilosa Ledeb. extract, 10 parts of Lycium barbarum extract, 10 parts of Ligusticum wallichii extract, 10 parts of resveratrol, 10 parts of longan pulp extract, 8 parts of Polygonum cuspidatum extract, 8 parts of Rubus idaeus extract, 6 parts of garlic extract, 6 parts of polyethylene glycol - 400, 2 parts of glycerol, 4 parts of butanediol and 50 parts of water.

[0040] Example 7

[0041] 8 parts of Agrimonia pilosa Ledeb. extract, 10 parts of Lycium barbarum extract, 10 parts of Ligusticum wallichii extract, 10 parts of resveratrol, 10 parts of longan pulp extract, 8 parts of Polygonum cuspidatum extract, 8 parts of Rubus idaeus extract, 10 parts of garlic extract, 2 parts of polyethylene glycol - 400, 3 parts of glycerol, 3 parts of butanediol and 50 parts of water.

[0042] Comparative Example 1

[0043] Compared with Example 1, the difference is that Agrimonia pilosa Ledeb. extract is not added, and the same amount of water is added, and the proportions of the other components remain unchanged.

[0044] Comparative Example 2

[0045] Compared with Example 1, the difference is that wolfberry extract is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0046] Comparative Example 3

[0047] Compared with Example 1, rhizoma chuanxiong extract is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0048] Comparative Example 4

[0049] Compared with Example 1, resveratrol is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0050] Comparative Example 5

[0051] Compared with Example 1, polygonum cuspidatum extract is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0052] Comparative Example 6

[0053] Compared with Example 1, longan pulp extract is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0054] Comparative Example 7

[0055] Compared with Example 1, raspberry extract is not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0056] Comparative Example 8

[0057] Compared with Example 1, agrimonia pilosa extract and wolfberry extract are not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0058] Comparative Example 9

[0059] Compared with Example 1, agrimonia pilosa extract and resveratrol are not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0060] Comparative Example 10

[0061] Compared with Example 1, polygonum cuspidatum extract, raspberry extract and longan pulp extract are not added, and the same amount of water is added while the proportions of the other components remain unchanged.

[0062] Among them, the preparation method of the agrimonia pilosa extract in the examples and comparative examples includes the following steps:

[0063] Step 1: Take fresh agrimonia pilosa leaves, wash, cut into sections, dry at 60 °C, crush with a pulverizer, and sieve through a 100-mesh sieve to obtain agrimonia pilosa leaf powder;

[0064] Step 2: Weigh 10 g of Agrimonia pilosa Ledeb. leaf powder, add an ethanol aqueous solution with a solid-liquid ratio of 1:10 and a concentration of 50 wt% for extraction at a temperature of 65 °C for 3 times, 2 h each time. After extraction, centrifuge at a speed of 4000 r / min for 5 min, collect and combine the supernatant, and then concentrate the supernatant under reduced pressure to 15 g to obtain the concentrated Agrimonia pilosa Ledeb. leaf extract;

[0065] Step 3: Then add 10 times the volume of glycerol and butanediol (mass ratio 1:1) for re-dissolution, add 0.5 wt% activated carbon and let it stand for 8 h, and filter through a 0.45 μm membrane to obtain the Agrimonia pilosa Ledeb. leaf extract.

[0066] The preparation method of the compositions in the examples and comparative examples is to mix and stir all components evenly at room temperature to obtain.

[0067] To verify the anti-aging effect of the composition of the present invention, the following tests were carried out:

[0068] (I) Safety test

[0069] Perform a human safety patch test on the compositions prepared in all the above examples and comparative examples. The test method refers to the human skin patch test in the "2015 Cosmetics Safety and Technology Specifications". The method of the skin closed patch test is as follows: Select 90 male volunteers aged 18 - 50 years old, randomly divide them into 18 groups, 5 in each group. Select a qualified patch test device with an area not exceeding 50 mm 2 and a depth of about 1 mm. Take 0.020 mL of the compositions prepared in the above examples and comparative examples and put them into the small chamber of the patch tester. The control hole is a blank control (without any substance). Stick the patch tester with the repair and firming composition on the flexor side of the forearm of the subject, and gently press with the palm to make it evenly adhere to the skin for 24 h. Observe the skin reaction according to the criteria in Table 1 at 30 min (after the indentation disappears), 24 h, and 48 h after removing the patch tester, and record the observation results.

[0070] Table 1 Observation criteria

[0071] - 0 Negative reaction ± 1 Suspicious reaction, only faint erythema + 2 Weak positive reaction (erythema reaction), erythema, infiltration, edema, may have papules ++ 3 Strong positive reaction (herpes reaction), erythema, infiltration, edema, papules, herpes; the reaction may extend beyond the test area +++ 4 Very strong positive reaction (confluent herpes reaction), obvious erythema, severe infiltration, edema, confluent herpes; the reaction extends beyond the test area

[0072] The experimental results show that there is no positive reaction, and the compositions prepared in all examples and comparative examples pass the human patch safety test.

[0073] (II) Research on the in vitro antioxidant effect of the composition

[0074] 1. ABTS radical scavenging effect

[0075] Prepare 7 mmol / L ABTS⁺ solution and 2.45 mmol / L potassium persulfate solution with distilled water (let stand at room temperature for 16 h before use). Mix the ABTS⁺ and potassium persulfate solutions in a volume ratio of 1:1, and dilute the mixture with a 5 mmol / L phosphate buffer solution at pH 7.4 to an absorbance value A of 0.70 ± 0.02 at 734 nm before use. Prepare the compositions in Examples 1 - 7 and Comparative Examples 1 - 10 into test samples with a concentration of 1 mg / mL with distilled water. Take 0.5 mL of the test sample and mix it with 0.5 mL of the ABTS⁺ solution, let stand for 10 min, and then measure its absorbance at 734 nm. Use deionized water and a 1 mg / mL VC aqueous solution to replace the sample as the blank control and positive control respectively. The ABTS radical scavenging rate is calculated according to the following formula:

[0076] ABTS radical scavenging rate / % = (A0 - AS) / A0 × 100;

[0077] In the formula, A0 is the absorbance value of the blank control group; AS is the absorbance value of the sample group.

[0078] 2. Superoxide anion radical scavenging effect

[0079] Prepare the compositions in Examples 1 - 7 and Comparative Examples 1 - 10 into test samples with a concentration of 1 mg / mL with distilled water. Take 0.4 mL of the sample solution and add 0.4 mL of 50 mmol / L Tris-HCl buffer solution (pH 8.3), and use distilled water to replace the sample as the blank control group. Mix well by shaking, incubate in a water bath at 25 °C for 10 min, then add 0.1 mL of 1.5 mmol / L pyrogallol hydrochloride solution (preheated in a 25 °C water bath), mix quickly and react for 5 min, and measure the absorbance value at 320 nm every 30 s. Use deionized water and a 1 mg / mL VC aqueous solution to replace the sample as the blank control and positive control respectively. Make a regression equation of the absorbance value changing with time, the slope of the curve is the pyrogallol autoxidation rate, and the scavenging ability of the sample to superoxide anion is calculated according to the following formula:

[0080] Superoxide anion radical scavenging rate / % = (ΔA0 / min - ΔAs / min) / ΔA0 / min × 100;

[0081] In the formula, ΔA0 / min: the slope of the absorbance value curve of the blank control group; ΔAs / min: the slope of the absorbance value curve of the sample group.

[0082] 3. Test results of the antioxidant capacity of the composition

[0083] The ABTS radical scavenging effect and superoxide anion radical scavenging effect of the composition of the present invention are shown in Table 2. It can be seen from the results that the scavenging rates of the composition of the present invention for the above two radicals can reach more than 85%. The highest scavenging effect on ABTS radicals can reach 97.1%, and the highest scavenging effect on superoxide anion radicals can reach 96.3%. The effect is even better than that of VC, indicating that the composition of the present invention has excellent antioxidant effects.

[0084] Table 2 Antioxidant effect test of the composition

[0085] ABTS free radical scavenging effect Superoxide anion free radical scavenging effect Example 1 91.5% 92.1% Example 2 87.4% 89.3% Example 3 89.6% 88.7% Example 4 85.3% 86.2% Example 5 90.5% 93.6% Example 6 90.4% 90.8% Example 7 97.1% 96.3% Comparative example 1 78.6% 76.3% Comparative example 2 80.1% 79.2% Comparative example 3 75.4% 77.6% Comparative example 4 73.1% 75.8% Comparative example 5 72.6% 70.4% Comparative example 6 76.5% 73.4% Comparative example 7 69.3% 66.2% Comparative example 8 52.5% 51.8% Comparative example 9 49.6% 50.7% Comparative example 10 34.3% 36.8% Positive control group 80.7% 83.5%

[0086] (III)Human skin resilience test

[0087] Take the compositions in Examples 1, 4, and 6, and Comparative Examples 1, 3, 6, 8, and 10 of the present invention and add them to the following conventional cosmetic cream matrixes according to a mass ratio of 1% respectively: C12-15 alkyl benzoate 25%, acrylate / C10-30 alkyl acrylate cross-linked polymer 0.25%, 1,3-butanediol 1.5%, glycerol 1.5%, polydimethylsiloxane PEG-7 isostearate 0.5%, triethanolamine 0.25%, DMDM hydantoin 0.4%, test composition 1%, and the balance is water.

[0088] Select 45 volunteers aged 40-50 years old (including 18 males and 27 females). The exclusion criteria for the volunteers meet the exclusion criteria in the "Diagnostic Criteria and Treatment Principles for Cosmetic Contact Dermatitis". The volunteers are randomly divided into 9 groups, with 5 people in each group, including 2 males and 3 females in each group. One group uses a conventional cosmetic matrix without adding the test sample. During the test period, the subjects apply 1 g of the same amount of the test cream on the face every morning and evening and smear it until fully absorbed, and use it continuously for 4 weeks. At the same time, other cosmetics cannot be applied to the experimental parts of the volunteers' faces during the test period.

[0089] Select the left and right cheekbones of the subjects' faces, the left and right cheeks at the intersection of the tip of the nose and the pupil, and the left and right sides at the intersection of the temple and the corner of the mouth as the test areas. Use a skin elasticity tester (Cutometer dual MPA580) to measure the elasticity values of the subjects' smeared parts before the test. Apply it twice every morning and evening, and use the photos before application as a control. During the experiment, the subjects cannot apply any other cosmetics. After the subjects continuously use the anti-wrinkle cosmetics for four weeks, compare the skin elasticity values before and after using the cosmetics in the examples and comparative examples. Statistically analyze the values measured for the experimental parts of the subjects each time, and analyze the change law of their skin elasticity to evaluate the change of their skin elasticity.

[0090] As can be seen from the data in Table 3, the cream prepared with the composition of the present invention can effectively shorten the skin rebound time two weeks after application, and the samples of the examples are superior to the comparative examples in terms of the effect of shortening the skin rebound time.

[0091] Table 3 Results of skin rebound time and rebound rate

[0092]

[0093] This experiment shows that the composition in the present invention is natural, safe, mild and non-irritating. The product obtained by applying the solution provided by the present invention has excellent antioxidant effects, can effectively reduce the skin rebound time, delay skin aging, prove that the composition of the present invention has good anti-wrinkle repair and firming effects, and thus significantly improve the skin aging state.

[0094] The above embodiments are the preferred embodiments of the present invention, but the embodiments of the present invention are not limited by the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications made without departing from the spirit and principle of the present invention shall be equivalent replacement methods and are all included in the protection scope of the present invention.

Claims

1. A firming and anti-aging composition, characterized in that, Prepared from the following raw materials in parts by mass: 6 - 15 parts of Agrimonia pilosa Ledeb. extract, 6 - 15 parts of Lycium barbarum extract, 5 - 12 parts of Ligusticum chuanxiong extract, 6 - 10 parts of resveratrol, 6 - 10 parts of longan pulp extract, 4 - 8 parts of Polygonum cuspidatum extract, 4 - 8 parts of Rubus idaeus extract, 0.5 - 15 parts of polyethylene glycol - 400, 1 - 7 parts of glycerol, 1 - 7 parts of butanediol, and 40 - 80 parts of water; Preparation method of Agrimonia pilosa Ledeb. extract Comprising the following steps: Step 1: Take fresh Agrimonia pilosa Ledeb. leaves, wash, cut into sections, dry at 50 - 70 °C, pulverize with a pulverizer, and sieve through 100 - 400 meshes to obtain Agrimonia pilosa Ledeb. leaf powder; Step 2: Weigh an appropriate amount of Agrimonia pilosa Ledeb. leaf powder, add a solvent with an appropriate solid - liquid ratio for extraction, at a temperature of 45 - 80 °C, extract 2 - 4 times, each time for 1 - 3 h. After extraction is completed, centrifuge at a speed of 4000 r / min for 5 min, collect and combine the supernatant, and then concentrate the supernatant under reduced pressure to 1 - 5 times the weight of the Agrimonia pilosa Ledeb. leaf powder to obtain the concentrated Agrimonia pilosa Ledeb. leaf liquid; Step 3: Then add an appropriate amount of stabilizer for re - dissolution, add activated carbon and let stand for 4 - 8 h, and filter through a membrane to obtain the Agrimonia pilosa Ledeb. leaf extract; The solid - liquid ratio in Step 2 is 1:(6 - 25), the extraction solvent is ethanol or its aqueous ethanol solution, and the extraction method is heating and stirring extraction or ultrasonic extraction; the concentrated Agrimonia pilosa Ledeb. leaf liquid in Step 2 also undergoes one or more steps of alcohol precipitation or resin purification before entering Step 3; the stabilizer in Step 3 is one or more of glycerol, butanediol, and propylene glycol; the process of alcohol precipitation is to add 2 - 4 times anhydrous ethanol, let stand for 8 - 16 h, collect the precipitated part, dissolve it in water, and then concentrate under reduced pressure; the process of resin purification is to add the concentrated liquid to the resin, wash with deionized water until transparent, and then elute with an aqueous ethanol solution, and collect the eluate.

2. The anti-aging and firming composition according to claim 1, wherein It also includes 6 - 10 parts of garlic extract.

3. The anti-aging and anti-initial aging composition according to claim 1 or 2, characterized in that The mass ratio of the Agrimonia pilosa Ledeb. extract: Lycium barbarum extract: Ligusticum chuanxiong extract is (1 - 2):(1 - 2):(0.5 - 3).

4. Use of a firming and anti-aging composition according to any one of claims 1-3 in the preparation of a cosmetic having anti-wrinkle and moisturizing effects and improving skin elasticity, characterized in that, A topical skin preparation with anti - wrinkle repair, moisturizing, and improving skin elasticity prepared by adding conventional pharmaceutical or cosmetic excipients or auxiliary components.

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