Combined carotid artery stent

Abstract

The present invention discloses a modular carotid artery stent comprising a connected cutting segment and a braided segment. The cutting segment is laser-engraved from a metal tube, while the braided segment is woven from metal braided wire. The cutting segment has a closed-loop structure. The closed-loop structure of the cutting segment can provide a large and uniform radial support force, better supporting stenosis; the braided segment provides good flexibility and compliance, with minimal vascular irritation. The present invention combines the cutting and braided segments into a modular carotid artery stent, which combines good radial support force and compliance, making it ideal for treating patients with multiple intracranial artery stenoses.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a combined carotid artery stent. Background Art

[0002] Currently, the treatments for intracranial artery stenosis mainly include drug therapy, balloon angioplasty and stent implantation. For patients with more severe stenosis, stent implantation is the main choice.

[0003] According to the processing method of the stent, the stents used to treat intracranial artery stenosis can be divided into laser-engraved stents and braided stents. Among them, the laser-engraved stent has a larger radial support force but poor flexibility, while the braided stent has good flexibility but insufficient radial support force.

[0004] At present, a considerable proportion of patients have multiple stenosis lesions in their intracranial carotid arteries. The stenotic segment requires the placement of a stent with greater support force, while the non-stenotic segment requires the placement of a stent with good flexibility. A single type of stent can no longer meet the needs. Summary of the Invention

[0005] The main purpose of the present invention is to provide a combined carotid artery stent, which aims to solve the problem of multiple stenosis lesions in the patient's intracranial carotid artery.

[0006] To achieve the above-mentioned purpose, the present invention proposes a combined carotid artery stent, which includes a cutting segment and a braided segment connected to each other. The cutting segment is formed by laser engraving a metal tube, and the braided segment is braided with metal braided wire, and the cutting segment is a closed-loop structure.

[0007] In some embodiments, the cutting segment comprises:

[0008] a plurality of sinusoidal ribs, wherein the plurality of sinusoidal ribs are spaced apart along the circumference of the combined carotid artery stent, and each of the sinusoidal ribs extends along the axial direction of the combined carotid artery stent;

[0009] A plurality of connecting ribs, wherein the connecting ribs are spaced apart along the circumferential direction and the axial direction of the combined carotid artery stent, and the two ends of each connecting rib are respectively connected to two adjacent sinusoidal wave ribs;

[0010] A plurality of bone-like tendons, wherein two ends of each bone-like tendon are respectively connected to the same side end portions of two circumferentially adjacent sinusoidal wave tendons;

[0011] The sinusoidal ribs, the connecting ribs and the bone-shaped ribs together enclose and form the closed-loop structure.

[0012] In some embodiments, in the circumferential direction of the combined carotid stent, the crests and troughs of two adjacent sinusoidal wave ribs are opposite, and the two ends of the connecting rib are respectively connected to the opposite crests and troughs of the two adjacent sinusoidal wave ribs.

[0013] In some embodiments, the plurality of connecting ribs are alternately and staggeredly distributed in the circumferential direction of the combined carotid artery stent.

[0014] In some embodiments, in the circumferential direction of the combined carotid artery stent, two adjacent connecting ribs extend in opposite directions.

[0015] In some embodiments, two limiting ribs are spaced apart on the bone-like tendons, and the braided segment has a plurality of extended braiding wires corresponding to the plurality of bone-like tendons. The extended braiding wires are wrapped around and fixed to the corresponding bone-like tendons and are located between the two limiting ribs.

[0016] In some embodiments, the braided wire is made of nickel-titanium alloy or cobalt-chromium alloy, the outer contour of the cross section of the braided wire is circular, and the diameter of the braided wire is 0.02-0.05 mm.

[0017] In some embodiments, the braided segment comprises a plurality of braided cells, each of which has an area of ​​0.5-1 mm 2 .

[0018] In some embodiments, at least two cutting segments are provided, and at least two braiding segments are provided, and the cutting segments and the braiding segments are alternately distributed and connected.

[0019] In some embodiments, the combined carotid artery stent is a self-expanding stent, and the combined carotid artery stent is cylindrical after expansion, and the outer diameter of the combined carotid artery stent after expansion is in the range of 3-8 mm; and / or,

[0020] The axial length of the combined carotid artery stent after expansion is 40-100 mm, wherein the axial length ratio of the cutting segment to the braided segment is (0.8-1):1.

[0021] The combined carotid artery stent provided by the present invention includes a cutting segment and a braided segment that are connected to each other. The cutting segment is made of a metal tube through laser engraving, and the cutting segment adopts a closed-loop structure, which can provide a large and uniform radial support force and better support the stenosis lesions; the braided segment is woven with metal braided wire, and the braided segment can provide good flexibility and softness, and has less irritation to blood vessels; the present invention combines the braided segment and the cutting segment into a combined carotid artery stent, which can have both good radial support force and softness, and is very suitable for treating patients with multiple stenosis lesions in the intracranial carotid artery. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0023] Figure 1 This is a schematic structural diagram of an embodiment of the combined carotid artery stent provided by the present invention after expansion;

[0024] Figure 2 for Figure 1 Schematic diagram of the partial structure of the cutting segment in the modular carotid artery stent.

[0025] Description of Figure Numbers:

[0026] 100 - modular carotid artery stent; 10 - braided segment; 11 - extended braided wire; 12 - braided cell 12; 20 - cutting segment; 21 - sinusoidal ribs; 22 - connecting ribs; 23 - bone-like ribs; 231 - limiting convex ribs.

[0027] The purpose, features and advantages of the present invention will be further described with reference to the accompanying drawings and in conjunction with the embodiments. DETAILED DESCRIPTION

[0028] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0029] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0030] In the present invention, unless otherwise specified or limited, the terms "connection" and "fixation" should be understood in a broad sense. For example, "fixation" can mean fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two elements or interaction between two elements, unless otherwise specified. Those skilled in the art will be able to understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0031] In addition, in the present invention, descriptions such as "first" and "second" are for descriptive purposes only and should not be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the technical solutions between the various embodiments can be combined with each other, but this must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0032] At present, a considerable proportion of patients have multiple stenotic lesions in their intracranial arteries. The stenotic segments require the placement of stents with greater support force, while the non-stenotic segments require the placement of stents with good flexibility. A single type of stent can no longer meet the needs.

[0033] To address the problem of multiple stenosis lesions in the intracranial carotid arteries of patients, the present invention combines the advantages of laser-engraved stents and braided stents to provide a combined carotid artery stent 100 that has both a laser-engraved section (i.e., cutting section 20) and a braided section 10. The laser-engraved section (i.e., cutting section 20) can provide greater radial support force, and the braided section 10 can provide good flexibility, which can benefit patients with multiple stenosis lesions in the intracranial arteries.

[0034] Please refer to Figure 1 As shown, in an embodiment of the present invention, the combined carotid stent 100 includes a cutting segment 20 and a braided segment 10 connected to each other. The cutting segment 20 is made of a metal tube by laser engraving, and the braided segment 10 is braided with metal braided wire, and the cutting segment 20 is a closed loop structure.

[0035] Specifically, the cutting segment 20 is made of an alloy tube laser engraved on a laser cutting machine. It can be a nickel-titanium alloy tube, which is a superelastic memory material. The cutting segment 20 has greater elasticity, which is convenient for self-expansion release or recovery. In addition, the cutting segment 20 adopts a closed-loop structure design, so that the cutting segment 20 can provide a larger and uniform radial support force to better support the stenosis lesion.

[0036] The braided segment 10 is seamlessly woven with 12 or 16 or other reasonable number of braided wires. The material of the braided wire can be nickel-titanium alloy or cobalt-chromium alloy. The outer contour of the cross section of the braided wire is circular, and its diameter can be selected from 0.02-0.05mm (such as 0.02mm, 0.03mm, 0.04mm, 0.05mm and the interval between any two end points). This facilitates the braiding operation, and the braided segment 10 has good elasticity, which is convenient for self-expansion release or recovery and transportation.

[0037] It should be noted that, since the intersections of the braided wires are not fixedly connected, the braided segment 10 is relatively soft and has good flexibility and compliance. It causes less stimulation to the blood vessels when treating diseased blood vessels and can better adapt to tortuous diseased blood vessels.

[0038] The braided segment 10 and the cutting segment 20 of the present invention are both self-expanding stents, which can undergo self-expansion release or recovery and transportation, and after expansion, they both form a cylindrical shape with both ends open. That is, the combined carotid artery stent 100 forms a cylindrical structure with both ends open after expansion and release.

[0039] The cutting segment 20 adopts a closed-loop structure, which can provide a large and uniform radial support force to better expand the stenosis lesions; the braided segment 10 can provide good flexibility and softness, and has less stimulation to the blood vessels; the present invention combines the braided segment 10 and the cutting segment 20 into a combined carotid artery stent 100, which can have both good radial support force and softness, and is very suitable for treating patients with multiple stenosis lesions in the intracranial arteries.

[0040] like Figure 1 and Figure 2 As shown, the cutting section 20 includes a plurality of sinusoidal ribs 21, a plurality of connecting ribs 22 and a plurality of bone-like ribs 23, wherein the plurality of sinusoidal ribs 21 are spaced apart along the circumference of the combined carotid stent 100; the plurality of connecting ribs 22 are spaced apart along the circumference and axial directions of the combined carotid stent 100, and the two ends of each connecting rib 22 are respectively connected to two adjacent sinusoidal ribs 21; the two ends of each bone-like rib 23 are respectively connected to the same side ends of two circumferentially adjacent sinusoidal ribs 21; the sinusoidal ribs 21, the connecting ribs 22 and the bone-like ribs 23 together enclose a closed loop structure.

[0041] Specifically, the sinusoidal ribs 21 are roughly sinusoidal in shape, with their length direction being the axial direction of the modular carotid stent 100, and are evenly spaced along the circumference of the modular carotid stent 100. The crests and troughs of two circumferentially adjacent sinusoidal ribs 21 may be opposite, or the crests and troughs may be offset, and the specific arrangement is not limited. The connecting rib 22 is located between two circumferentially adjacent sinusoidal ribs 21, and along the length direction of the sinusoidal ribs 21 (i.e., the axial direction of the modular carotid stent 100), a plurality of connecting ribs 22 are provided, and the multiple connecting ribs 22 are evenly spaced, and the two ends of each connecting rib 22 are respectively connected to two circumferentially adjacent sinusoidal ribs 21. The bone-like ribs 23 are located at both ends of the braided segment 10. Since the two ends of the sinusoidal wave ribs 21 are free ends, the ends on the same side of two adjacent sinusoidal wave ribs 21 in the circumferential direction are connected by the bone-like ribs 23. That is, the two ends of the bone-like ribs 23 are respectively connected to the free ends on the same side of two adjacent sinusoidal wave ribs 21 in the circumferential direction. In this way, the sinusoidal wave ribs 21, the connecting ribs 22 and the bone-like ribs 23 together form a plurality of closed-loop structures, which are the cutting segments 20.

[0042] The design of the sinusoidal ribs 21 in the cutting section 20 of the present invention can effectively improve the axial elasticity of the combined carotid stent 100, making the force transmission more gentle and less likely to cause stress concentration.

[0043] Furthermore, in some embodiments of the present invention, along the circumference of the modular carotid stent 100, the crests and troughs of two adjacent sinusoidal ribs 21 are opposite each other, and the ends of the connecting rib 22 are respectively connected to the opposite crests and troughs of the two adjacent sinusoidal ribs 21. This makes the structure more compact and improves overall stability.

[0044] Furthermore, in some embodiments of the present invention, multiple connecting ribs 22 are alternately and staggeredly distributed in the circumferential direction of the combined carotid stent 100. Such a design can effectively improve the circumferential uniform expansion capability of the combined carotid stent 100, so that the combined carotid stent 100 has uniform radial support force in the circumferential direction.

[0045] Furthermore, in some embodiments of the present invention, in the circumferential direction of the combined carotid stent 100, the extension directions of two adjacent connecting ribs 22 are opposite. Such a design can make the overall force of the combined carotid stent 100 more uniform, thereby enhancing the stent's ability to resist torsional deformation.

[0046] like Figure 1 and Figure 2 As shown, in some embodiments of the present invention, two limiting ribs 231 are arranged at intervals on the bone-like tendon 23, and the braiding segment 10 has a plurality of extended braiding wires 11, which are wound around and fixed to the bone-like tendon 23 and are located between the two limiting ribs 231, that is, the limiting ribs 231 can limit the winding position of the braiding wire 12 on the bone-like tendon 23 to a certain area.

[0047] Specifically, the bone-like tendons 23 are roughly dog-bone-shaped, with two spaced-apart retaining ribs 231 disposed thereon. The extended braided wire 11 is a free braided wire that extends from the braided segment 10. The corresponding extended braided wire 11 is wrapped around the bone-like tendons 23 and between the two retaining ribs 231. The head end of the wrapped extended braided wire 11 is then secured to the bone-like tendons 23 by soldering or laser welding. This allows for a relatively secure connection between the braided segment 10 and the cutting segment 20, and the operation is relatively simple. The retaining ribs 231 provide a preliminary positioning for the wrapped extended braided wire 11, preventing it from moving and affecting subsequent welding and securing operations.

[0048] It should be noted that, during the specific fixed connection, two or three extended braided wires 11 are wound around and fixed on the bone-like tendon 23 .

[0049] like Figure 1 As shown, the braided segment 10 includes a plurality of braided cells 12, each of which is roughly diamond-shaped and has an area of ​​0.5-1 mm. 2 (For example, 0.5mm 2 , 0.6mm 2 , 0.7mm 2 , 0.8mm 2 , 0.9mm 2 , 1mm 2 and the interval value between any two end point values). With such a design, the coverage rate of the braided wire is higher, which can better prevent the detachment of plaques when treating diseased blood vessels.

[0050] In some embodiments of the present invention, at least two cutting segments 20 and at least two braided segments 10 are provided, with the cutting segments 20 and braided segments 10 alternately arranged and connected. That is, the modular carotid stent 100 of the present invention includes two or more cutting segments 20 and two or more braided segments 10, with the cutting segments 20 and braided segments 10 alternately arranged and connected. The connection method can be referred to in the above embodiments and will not be further described here.

[0051] It should be noted that the specific number of cutting segments 20 and braided segments 10 can be reasonably designed based on the length of the stenotic blood vessel and the number of stenotic sites. Specifically, the number of cutting segments 20 is the same as the number of stenotic sites. When using the combined carotid artery stent 100 to treat a stenotic blood vessel, the cutting segment 20 is placed in the stenotic site and has greater support force, while the braided segment 10 is placed in the non-stenotic site and has good flexibility and compliance, with less irritation to the blood vessel and can better adapt to tortuous blood vessels. The axial length of the cutting segment 20 and the braided segment 10 can be designed based on actual needs. Specifically, the axial length of the cutting segment 20 is determined based on the length of the stenotic site within the stenotic blood vessel, and the axial length of the braided segment 10 is determined based on the length of the non-stenotic site within the stenotic blood vessel. When the combined carotid stent 100 includes two or more cutting segments 20, the axial lengths of the cutting segments 20 may be the same or different. When the combined carotid stent 100 includes two or more braided segments 10, the axial lengths of the braided segments 10 may be the same or different. No limitation is made here and all are within the scope of protection of the present invention.

[0052] like Figure 1 As shown, in some specific embodiments of the present invention, the combined carotid stent 100 includes two cutting segments 20 and two braided segments 10, and the two cutting segments 20 and the two braided segments 10 are alternately distributed and connected, which can be suitable for treating diseased blood vessels containing two stenotic areas and two non-stenotic areas.

[0053] In some embodiments of the present invention, the combined carotid stent 100 is a self-expanding stent. After expansion, the combined carotid stent 100 is cylindrical. The outer diameter range of the combined carotid stent 100 after expansion is 3-8 mm (for example, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm and the interval between any two end point values). The specific outer diameter can be determined according to the size of the blood vessel with stenosis.

[0054] Optionally, the axial length of the combined carotid stent 100 after expansion is 40-100mm (such as 40mm, 50mm, 60mm, 70mm, 80mm, 90mm, 100mm and the interval between any two endpoints), and its axial length is specifically determined according to the length of the blood vessel with the stenosis lesion, wherein the axial length ratio of the cutting segment 20 and the braided segment 10 is (0.8-1):1, for example, the axial length ratio of the two is 0.8:1, 0.9:1, 1:1 and the interval between any two endpoints. During the specific design, the axial length of the cutting segment 20 and the braided segment 10 can be determined according to the length of the stenosis part and the non-stenosis part in the blood vessel with the stenosis lesion. With such a design, the combined carotid stent 100 can have both good radial support and flexibility, and is very suitable for treating patients with multiple stenosis lesions in the intracranial arteries.

[0055] The above description is only a preferred embodiment of the present invention and does not limit the patent scope of the present invention. All equivalent structural transformations made by using the contents of the present invention description and drawings under the inventive concept of the present invention, or direct / indirect application in other related technical fields are included in the patent protection scope of the present invention.

Claims

1. A combined carotid artery stent, characterized in that: The combined carotid artery stent comprises a cutting segment and a braided segment connected to each other, wherein the cutting segment is formed by laser engraving a metal tube, and the braided segment is braided by metal braided wire, and the cutting segment is a closed-loop structure; The cutting section comprises: a plurality of sinusoidal ribs, wherein the plurality of sinusoidal ribs are spaced apart along the circumference of the combined carotid artery stent, and each of the sinusoidal ribs extends along the axial direction of the combined carotid artery stent; A plurality of connecting ribs, each of which is spaced apart along the circumferential and axial directions of the combined carotid artery stent, the connecting ribs being located between two adjacent sinusoidal wave ribs in the circumferential direction and evenly spaced along the length of the sinusoidal wave ribs, with each connecting rib having two ends connected to two adjacent sinusoidal wave ribs in the circumferential direction; A plurality of bone-like tendons, wherein two ends of each bone-like tendon are respectively connected to the same side end portions of two circumferentially adjacent sinusoidal wave tendons; The sinusoidal ribs, the connecting ribs and the bone-shaped ribs together enclose the closed-loop structure; Two limiting convex ribs are arranged on the bone-like tendons at intervals, and the braided segment has a plurality of extended braiding wires corresponding to the plurality of the bone-like tendons. Two or three of the extended braiding wires are wound around and fixed to the corresponding bone-like tendons and are located between the two limiting convex ribs. At least two cutting segments are provided, and at least two braiding segments are provided. The cutting segments and the braiding segments are alternately distributed and connected, and the axial length ratio of the cutting segments to the braiding segments is (0.8-1):1; The braided segment includes a plurality of braided cells, and the area of ​​the braided cells is 0.5-1 mm 2 ; The combined carotid artery stent is a self-expanding stent. After expansion, the combined carotid artery stent is cylindrical. The outer diameter of the combined carotid artery stent after expansion is in the range of 3-8 mm.

2. The combined carotid artery stent according to claim 1, wherein: In the circumferential direction of the combined carotid artery stent, the crests and troughs of two adjacent sinusoidal wave ribs are opposite to each other, and the two ends of the connecting rib are respectively connected to the opposite crests and troughs of the two adjacent sinusoidal wave ribs.

3. The combined carotid artery stent according to claim 2, wherein: In the circumferential direction of the combined carotid artery stent, the plurality of connecting ribs are alternately and staggeredly distributed.

4. The combined carotid artery stent according to claim 3, wherein: In the circumferential direction of the combined carotid artery stent, the extension directions of two adjacent connecting ribs are opposite.

5. The combined carotid artery stent according to claim 1, wherein: The braided wire is made of nickel-titanium alloy or cobalt-chromium alloy, the outer contour of the cross section of the braided wire is circular, and the diameter of the braided wire is 0.02-0.05 mm.

6. The combined carotid artery stent according to any one of claims 1 to 5, characterized in that: The axial length of the combined carotid artery stent after expansion is 40-100 mm.

Images