An automated sample detection system and method of use using magnetic droplets as a carrier for reactants
By using magnetic droplets as reactant carriers and driving them to move, split, and fuse on a track using electromagnetic fields, the problem of low sample transport and reaction efficiency in existing fully automated laboratory systems is solved, achieving efficient, safe, and low-cost chemical detection.
Patent Information
- Application Number
- CN202410730360.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-06
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2044-06-06
AI Technical Summary
Existing fully automated laboratory systems are inefficient in sample transport and reaction processes, require a large area, and are expensive, complex, and difficult to adapt to the transport needs of irregularly shaped or fragile items.
Using magnetic droplets as reactant carriers, the magnetic droplets are driven by electromagnetic fields to move, split, and merge on a track. The magnetic droplet robot is controlled by a combined drive platform and a touch-screen LCD human-machine interface to complete the chemical reaction.
It improves detection efficiency, reduces the safety risks of manual operation, lowers equipment costs, occupies little space, is highly adaptable, and is suitable for a variety of chemical detection fields.
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Figure CN118534144B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The application relates to an automatic sample detection system using magnetic liquid droplets as reaction carrier and a use method thereof, and belongs to the technical field of laboratory automation equipment. BACKGROUND
[0002] In the medical field, sample detection technology is a key link to realize precision medicine, which combines many advanced technologies and methods such as chemistry, biology and engineering technology. These technologies are used for disease diagnosis, monitoring and research, providing support for laboratory, industrial application and clinical detection. At present, for a certain detection process, such as new coronavirus detection, a special automatic assembly line can be designed to execute it.
[0003] Such an assembly line, i.e. total laboratory automation (TLA), covers the whole process from sample collection to output of test report and sample storage, significantly improving the efficiency and safety of sample management, and shortening and unifying the turnaround time.
[0004] The total laboratory automation system includes four main parts: sample collection and transmission, sample pretreatment, sample analysis and sample post-treatment. The total laboratory automation system not only saves labor and time cost, but also improves the efficiency of the process and the reliability of the results.
[0005] However, even highly automated systems face challenges, especially in sample transportation and reaction. If the initial test result is abnormal, it is usually necessary to retest to rule out the interference of instruments or reagents. The current sample detection process usually includes the following steps: collect samples of a group, store them, then add detection reagents by mechanical arm or manually, react for a period of time, then send to another machine for analysis, circulate between machines for a certain number of times, and finally take out the waste for disposal. This process is complicated, time-consuming, and the machines involved in the circulation occupy a large space.
[0006] The following methods are mainly used in the current domestic total laboratory automation system technology:
[0007] 1. Manual operation technology: manual use of vessels to hold reagents and reactants, manual transportation and mixing, and chemical reaction.
[0008] 2. Mechanical arm conveyor line technology: use of mechanical arms and other automation devices to transport and control vessels, mix reagents and reactants, and complete chemical reactions.
[0009] 3. Conveyor belt transportation: modern conveyor belt systems can be designed to different lengths, widths and shapes according to needs to adapt to different industrial applications, and can work with other automation equipment such as robots, sensors and control systems.
[0010] 4. Instrument detection technology: the reagent is added into the feeding port of the machine, and the machine itself performs the transportation operation and analyzes the reaction result.
[0011] The existing method also has the following disadvantages:
[0012] 1. Manual operation technology: this scheme has low efficiency, high labor cost, and problems in operation accuracy and safety.
[0013] 2. Mechanical arm conveyor line technology: 1. This technology needs to use precise electromechanical instruments such as mechanical arms, which is expensive and needs regular maintenance, and the cost is high. 2. It is relatively complex to use, and requires a certain knowledge base, which is not easy to learn. 3. Poor flexibility, needs to be reprogrammed for different working conditions. 4. Large floor area, increasing the size of the whole laboratory automation system.
[0014] 3. Conveyor transportation: high initial investment cost and large floor area. For irregular-shaped, fragile or special handling conditions, the conveyor is less suitable. And once installed, it is difficult and costly to modify its path and function.
[0015] 4. Instrument detection technology: low efficiency, expensive instruments, not suitable for large-scale detection.
[0016] Therefore, how to improve the efficiency of sample transportation and reaction and reduce the operation space has become a problem that technicians need to solve urgently. SUMMARY
[0017] Objective: In order to overcome the deficiencies in the prior art, the present application provides an automatic sample detection system using magnetic liquid droplets as reaction carriers and a use method.
[0018] Technical scheme: In order to solve the above technical problems, the technical scheme adopted by the present application is:
[0019] In a first aspect, an automatic sample detection system using magnetic liquid droplets as reaction carriers comprises: a magnetized liquid droplet motion functional track, a combined driving platform, a touch LCD man-machine interactive display screen, and a controller.
[0020] The combined driving platform is provided above the magnetized liquid droplet motion functional track.
[0021] The controller is connected with the touch LCD man-machine interactive display screen and the electronic relay module respectively, and the electronic relay module is used to control the combined driving platform.
[0022] The combined drive platform comprises a plate body, a PCB board arranged in the plate body, a plurality of power access terminals arranged on the PCB board, a relay board arranged on the PCB board, the power access terminals connected with power terminals of the relay board, and the power terminals of the relay board connected with an electronic relay module. A plurality of electromagnetic coils arranged in an array are further arranged in the plate body, and each relay in the electronic relay module controls an electromagnetic coil to open and close.
[0023] The magnetized liquid droplet motion functional track comprises a track plate body, a plurality of operation areas arranged on the track plate body, a waiting area and a reaction area, the waiting area connected with the reaction area through a transportation channel, and a cutting edge arranged at the edge of the waiting area. A recovery area is further arranged on the track plate body, and the reaction areas of all the operation areas are connected with the recovery area through the transportation channel.
[0024] Further, a feedback camera is further included, the feedback camera arranged above the magnetized liquid droplet motion functional track and connected with a controller.
[0025] Further, the electromagnetic coils are circular electromagnetic coils.
[0026] Further, the electromagnetic coils are hexagonal electromagnetic coils arranged in an array to form a PCB honeycomb linear array.
[0027] Further, a magnetic liquid droplet robot is further included, the magnetic liquid droplet robot using artificial mixed oil containing magnetic nanoparticles.
[0028] Further, the touch-type LCD man-machine interaction display screen displays an M*N touch point matrix, each touch point corresponding to control of an electromagnetic coil, and each touch point including two functional areas, one functional area for control of a forward current of the electromagnetic coil and the other functional area for control of a reverse current of the electromagnetic coil.
[0029] Further, a handle is further included, the handle connected with the controller, the handle provided with four keys of front, back, left and right for control of opening and closing of the electromagnetic coils, so that the magnetic liquid droplet robot moves in a corresponding direction of the handle keys on the magnetized liquid droplet motion functional track above the PCB honeycomb linear array.
[0030] Further, an equipment shell is further included, the equipment shell provided with a reaction area, a lifting support arranged in the reaction area, a combined drive platform arranged on the lifting support, a magnetized liquid droplet motion functional track arranged on the combined drive platform, and a feedback camera arranged above the magnetized liquid droplet motion functional track.
[0031] In a second aspect, a method for using an automated sample detection system using magnetic droplets as a reaction carrier includes the following steps:
[0032] Placing the sample to be detected on a marked point in the waiting area.
[0033] Placing the reactant on another marked point in the waiting area.
[0034] Touching the LCD man-machine interactive display screen to control the working state of the electromagnetic coil in the combined driving platform, so that the magnetic droplet robot passes through the cutting blade in the waiting area and is split into two magnetic droplet robots.
[0035] The two magnetic droplet robots are controlled by the touch LCD man-machine interactive display screen to complete the endocytosis of the sample to be detected and the reactant.
[0036] The two magnetic droplet robots after endocytosis are controlled by the touch LCD man-machine interactive display screen to enter the reaction area to generate a result product through fusion reaction.
[0037] The remaining magnetic droplet robots are controlled by the handle to control the working state of the electromagnetic coil in the combined driving platform, so that the remaining magnetic droplet robots follow the small magnetic balls above the PCB honeycomb linear array to move to the recycling area by changing the direction of the small magnetic balls.
[0038] Further, the method further includes: the feedback camera transmits the motion information of the magnetic droplet robot to the controller in real time, and gives a warning for the motion error state.
[0039] The method has the following advantages: the method uses magnetic droplets to wrap the reactant, and under the action of the electromagnetic array and the PCB inside the system, drives the magnetic droplets wrapped with the reactant to move, split, fuse, and ingest the reactant, and completes a series of actions such as chemical reaction. Since the magnetic droplets have stable chemical properties and good sealing, the reaction of the reactant wrapped by the magnetic droplets can effectively shield external interference. Since the magnetic droplets are liquid, they have high freedom of movement and are very flexible. The main component of the magnetic droplets is ferroferric oxide, which is simple to prepare. The driving equipment adopts a relay module, an FPGA control module, and a PCB driving module, and has simple principles, easy production, and low cost. The system has good scalability and can be arrayed, and can be operated singly or in batches in a short time and a small space, with high efficiency. The method solves the potential danger of manual detection, the interference of the external environment on the reaction, the complexity and high cost of existing automated equipment, the large floor area, and the low operation efficiency of existing detection equipment such as a mechanical arm.
[0040] Compared with the prior art, the method has the following advantages:
[0041] 1. High degree of automation, through program control electromagnetic field to complete the drive magnetic liquid droplet transport reagents, the entire detection process to avoid cumbersome manual operation.
[0042] 2. High safety, the entire reaction process in a closed system inside, avoid the operator directly contact with the reagents, improve the operation safety.
[0043] 3. Scalable operation, track allows multiple groups of magnetic liquid droplets to move, the system can also install multiple groups of combined drive platform, so you can simultaneously perform several groups of chemical reaction operation, detection efficiency.
[0044] 4. Wide application, involving many fields of chemical detection can use this set of equipment.
[0045] 5. Market competition advantage: compared with other chemical detection equipment, the equipment structure is simple, low cost, high efficiency, the space required for work can improve the market competitiveness of the product, bring greater business profits and development opportunities for enterprises. BRIEF DESCRIPTION OF DRAWINGS
[0046] Figure 1 is a schematic diagram of the structure of an automated sample detection system.
[0047] Figure 2 is a schematic diagram of the structure of an automated sample detection system circuit.
[0048] Figure 3 is a schematic diagram of the structure of a combined drive platform.
[0049] Figure 4 is a schematic diagram of the structure of a magnetized liquid droplet motion functional track.
[0050] Figure 5 is a schematic diagram of the structure of a magnetic liquid droplet robot.
[0051] Figure 6 is a schematic diagram of a touch LCD man-machine interactive display screen.
[0052] Figure 7 is a schematic diagram of a touch point control electromagnetic coil.
[0053] Figure 8 is a schematic diagram of the endocytosis process of a magnetic liquid droplet robot.
[0054] Figure 9 is a schematic diagram of a circular electromagnetic coil controlling the motion of a magnetic liquid droplet robot.
[0055] Figure 10 is a schematic diagram of an electronic relay module structure.
[0056] Figure 11 is a schematic diagram of a honeycomb-shaped PCB. Detailed Implementation
[0057] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present invention.
[0058] The present invention will be further described below with reference to specific embodiments.
[0059] Example 1:
[0060] like Figure 1 As shown in the figure, this embodiment introduces an automated sample detection system using magnetic droplets as reactant carriers, including: a feedback camera 1, a magnetic droplet motion functional track 2, a combined drive platform 3, a touch LCD human-machine interaction display screen 4, a device housing 5, and a lifting bracket 6.
[0061] The device housing 5 has a reaction area, a lifting bracket 6 is provided in the reaction area, a combined drive platform 3 is provided on the lifting bracket 6, a magnetized droplet motion functional track 2 is provided on the combined drive platform 3, and a feedback camera 1 is provided above the magnetized droplet motion functional track 2.
[0062] The device housing 5 is also equipped with a touch-screen LCD human-machine interaction display screen 4.
[0063] The device housing 5 is also equipped with an electronic relay module 7 and a field-programmable gate array 8.
[0064] like Figure 2 As shown, the field-programmable gate array 8 is connected to the touch LCD human-machine interaction display screen 4, the electronic relay module 7, and the feedback camera 1, respectively. The electronic relay module 7 is used to control the combined drive platform 3.
[0065] Furthermore, such as Figure 3 As shown, the combined drive platform 3 includes: a board 301, within which a PCB board is disposed, with a plurality of power input terminals 302 disposed on the PCB board, and a relay board 303 disposed on the PCB board. The power input terminals 302 are connected to the power supply terminals of the relay board 303, and the power supply terminals of the relay board 303 are connected to the electronic relay module 7. The board 301 also contains a plurality of electromagnetic coils arranged in an array, and each relay in the electronic relay module 7 controls the opening and closing of one electromagnetic coil.
[0066] Further, the electromagnetic coil is arranged as a circular electromagnetic coil 304.
[0067] Further, the electromagnetic coil is arranged as a hexagonal electromagnetic coil 305, which is arranged in an array to form a PCB honeycomb linear array.
[0068] Further, as shown in Figure 4 The magnetized liquid droplet movement functional track 2 includes a track plate body 201, and a plurality of operation areas 202 are arranged on the track plate body 201. The operation areas 202 include a waiting area 2021 and a reaction area 2022. The waiting area 2021 and the reaction area 2022 are connected through a transportation channel 203. The edge of the waiting area 2021 is provided with a cutting edge 2023. The track plate body 201 is further provided with a recycling area 204. The reaction areas 2022 of all operation areas 202 are connected with the recycling area 204 through the transportation channel 203.
[0069] Further, the waiting area 2021, the reaction area 2022, and the recycling area 204 are each provided with a mark point corresponding to the position of the electromagnetic coil.
[0070] Further, the surfaces of the operation areas 202, the transportation channel 203, and the recycling area 204 are all hydrogel treated to reduce the resistance when the magnetic liquid droplets move.
[0071] Further, as shown in Figure 5 The magnetic liquid droplet robot 9 is made of artificial mixed oil containing magnetic nanoparticles. The magnetic liquid droplet robot 9 magnetizes the liquid to be reacted by taking advantage of the strong drivability and stable chemical properties of the magnetic liquid droplets. The magnetic liquid droplets are controlled by the electromagnetic field, so that they can change their shapes in multiple modes such as splitting, fusion, and displacement. Finally, the reactants are fused to complete the reaction.
[0072] Further, the touch type LCD man-machine interactive display screen 4 displays an M*N touch point matrix. Each touch point 401 corresponds to control of an electromagnetic coil. Each touch point 401 includes two functional areas. One functional area is used to control the forward current of the electromagnetic coil, and the other functional area is used to control the reverse current of the electromagnetic coil. As shown in Figure 6 The touch type LCD man-machine interactive display screen 4 displays a 4*5 touch point matrix. Each touch point is divided into upper and lower functional areas. After being touched, the direction of the current in the electromagnetic coil can be changed. As shown in Figure 7 The upper and lower functional areas A and B control the schematic diagram of the change of the magnetic pole of the electromagnetic coil.
[0073] Further, it further comprises a handle connected with the field programmable gate array 8, four buttons of front, back, left and right are arranged on the handle, which are used to control the opening and closing of the electromagnetic coil, so that the magnetized liquid drop robot 9 moves on the magnetized liquid drop movement functional track 2 above the PCB honeycomb linear array according to the corresponding direction of the handle button.
[0074] Embodiment 2:
[0075] The embodiment introduces a method for using an automatic sample detection system using magnetic liquid drops as reaction carrier, which comprises the following steps:
[0076] Place the sample to be detected on a mark point in the waiting area.
[0077] Place the reactant on another mark point in the waiting area.
[0078] Touch the LCD man-machine interactive display screen to control the working state of the electromagnetic coil in the combined driving platform, so that the magnetic liquid drop robot passes through the cutting blade in the waiting area and is split into two magnetic liquid drop robots.
[0079] The two magnetic liquid drop robots are respectively controlled by the touch LCD man-machine interactive display screen to complete the endocytosis of the sample to be detected and the reactant.
[0080] The two magnetic liquid drop robots after endocytosis are respectively controlled by the touch LCD man-machine interactive display screen to enter the reaction area for fusion reaction to generate the result product.
[0081] The remaining magnetic liquid drop robot is controlled by the handle to control the working state of the electromagnetic coil in the combined driving platform, so that the remaining magnetic liquid drop robot follows the small magnetic ball to move to the recycling area by changing the direction of the small magnetic ball above the PCB honeycomb linear array.
[0082] Further, it further comprises a feedback camera which transmits the movement information of the magnetic liquid drop robot to the field programmable gate array in real time and gives a warning for the movement error state.
[0083] Further, the method for controlling the working state of the electromagnetic coil in the combined driving platform by the touch LCD man-machine interactive display screen comprises:
[0084] The touch LCD man-machine interactive display screen controls the opening of the current electromagnetic coil where the magnetic liquid drop robot is located.
[0085] The touch LCD man-machine interactive display screen controls the opening of the adjacent electromagnetic coil on the movement path, and the magnetic poles are different, one end of the magnetic liquid drop robot is pulled into the path of the adjacent electromagnetic coil.
[0086] The touch LCD man-machine interactive display screen controls the closing of the current electromagnetic coil, and the magnetic liquid drop robot enters the path of the adjacent electromagnetic coil.
[0087] Further, the handle controls the working state of the electromagnetic coil in the combined driving platform, and the direction of the small magnetic ball above the PCB honeycomb linear array is changed, specifically including:
[0088] Press the handle direction key to control the current electromagnetic coil under the magnetic droplet robot to open.
[0089] Press the handle direction key again to control the adjacent electromagnetic coil on the motion path to open, and the current electromagnetic coil to close. The small magnetic ball on the PCB honeycomb linear array moves from the current electromagnetic coil to the adjacent electromagnetic coil corresponding path.
[0090] The magnetic droplet robot moves along the path following the small magnetic ball.
[0091] Embodiment 3:
[0092] This embodiment introduces the working principle of an automatic sample detection system using magnetic droplets as reaction carrier, as follows:
[0093] As shown in Figure 8 , after the magnetic droplet robot uniformly enters the inside of the reaction liquid, it can be used as the "driving core" of the sample liquid and the reaction liquid. Under the driving of the electromagnetic force, it moves and contacts to react. A large group of magnetized droplets can be split under the action of the magnetic field, and multiple magnetized droplets can work simultaneously to perform multiple reactions simultaneously, improving detection efficiency.
[0094] As shown in Figure 9 , the working state of the magnetic droplet robot under the control of the circular electromagnetic coil array, one circle is an electromagnet. A shows that when the current directions of the two adjacent circular electromagnetic coils are opposite, i.e., the magnetic pole directions of the electromagnets are different, the magnetized droplets will be pulled into a strip shape by the two electromagnetic coils. The current directions in the electromagnetic coils in the states shown in B1 and B2 suddenly change to be consistent, i.e., the magnetic pole directions of the two adjacent electromagnets suddenly change to be the same, and the long strip-shaped magnetized droplets in A will be pulled into two droplets, completing the splitting. If you want to complete the fusion operation, you only need to change the adjacent two electromagnetic coils to be different in name.
[0095] If one of the two adjacent electromagnets is turned off, the long strip state of the magnetized droplets can be canceled, and it will become a circular liquid group and be adsorbed to the top of an electromagnet. If this electromagnet is turned off and the adjacent electromagnet on the side (e.g., the right side) is turned on, the magnetized droplets can move one step to the right. The up and down motion is the same, and the process from B1, B2 to C1, C2 can be obtained.
[0096] One embodiment, 3 power access terminals, 3 terminals positive pole parallel access power positive. 3 terminal positive pole on the PCB board together with 96 lead wire connected to 96 row pin hole, hole corresponding to the setting of the relay board. Relay board on each wire corresponding to an electromagnetic coil. 96 relays in series between the electromagnetic coil and the wire hole. All the negative pole of the electromagnetic coil on the PCB board is common ground, and all the negative pole of the terminal is connected, and any terminal negative pole is connected to the battery negative pole.
[0097] As shown in Figure 10 , when a group of relays are all dialing to 1 gear, the current flows through the electromagnet in the positive direction; when a group of relays are all dialing to 2 gear, the current flows through the electromagnet in the reverse direction.
[0098] By default, when the upper touch point of the touch LCD is touched, the FPGA internal program is triggered, the FPGA sends a signal to the relay module, the relay in the forward loop is turned on, the electromagnetic coil is connected in the forward loop, and the corresponding positive magnetic field is generated; conversely, when the lower touch point is touched, a negative magnetic field is generated, and the above is repeated. The magnetic liquid droplet will change its position under the action of the external magnetic field. If the corresponding two magnetic poles of the touch module are controlled, the shape of the magnetic liquid droplet can be changed. Under the action of two different magnetic poles, the magnetic liquid droplet is stretched into a strip, and under the action of two same magnetic poles, the magnetic liquid droplet is divided into two. By generating the corresponding magnetic field through the above matrix touch module, the planar motion and shape change of the magnetic liquid droplet in the corresponding area can be realized.
[0099] The program uses Vivado to program the FPGA. First, the FPGA is programmed to the LCD touch screen, and the screen is given a color block identification at a specific position. The color block corresponds to one electromagnet in the electromagnet array. When the color block is touched, the corresponding instruction can be triggered, and the FPGA sends a string of code to the relay module to control the state of each relay, thereby controlling the state of the electromagnet array. Touching color block A triggers the FPAG to send a signal to the relay module, and the electromagnet at this position is powered on. Touching color block A again reverses the magnetic pole of the electromagnet at this position; touching color block B turns off the electromagnet at this position. The rest is the same.
[0100] The handle direction key can control the movement of the magnetic field on the honeycomb-shaped PCB, and then control the magnetic liquid droplet to move. As Figure 11 , the relay is now connected to the loop where the "F" coil is located. When the left key is pressed, this loop is disconnected, and the relay in the loop where the "E" coil is located is connected, that is, the magnetic field generated by the coil moves one unit to the left. In actual use, the magnetic liquid droplet on the PCB will be pulled to the left. The same is true for other directions.
[0101] The program is programmed by Labview. Firstly, the program sends initial state code to the relay. Then the program constantly detects the handle state connected with the device; when the direction key is pressed, the task corresponding to the direction key is triggered once. For example, when the right key is pressed, the program detects that the key is pressed and triggers the key-down task: sends 01 code to the relay (the bit number of the code is the same as the number of relays, 0 represents the corresponding serial number of the relay off, and 1 represents on), and processes on the basis of the original state code. Assuming that the original serial number a relay is on and the rest is off, now the serial number a+1 relay is on and the rest is off. On the PCB, it will be reflected that the original energized coil is de-energized, and the relay one grid to the right is energized, pulling the magnetic liquid drop to move to the right. Pressing other keys is the same.
[0102] The above only describes the preferred embodiments of the present application, and it should be noted that for ordinary skilled in the art, without departing from the principles of the present application, a number of improvements and refinements can be made, and these improvements and refinements should be considered as the protection scope of the present application.
Claims
1. An automated sample detection system using magnetic droplets as a carrier of reactants, characterized in that: It comprises: Magnetized droplet movement functional track, combined driving platform, touch LCD man-machine interactive display screen, controller; The combined driving platform is provided with a magnetized droplet movement functional track above. The controller is connected with the touch LCD man-machine interactive display screen and the electronic relay module respectively, and the electronic relay module is used for controlling the combined driving platform. The combined driving platform comprises a plate body, and a PCB is arranged in the plate body. The magnetized droplet movement functional track comprises a track plate body, and a plurality of operation areas are arranged on the track plate body. The touch LCD man-machine interactive display screen displays an M*N touch point matrix, each touch point corresponds to control of an electromagnetic coil, and each touch point comprises two functional areas. It further comprises a handle connected with the controller, and four keys of front, rear, left and right are arranged on the handle.
2. The automated sample detection system using magnetic droplets as reactant carriers according to claim 1, characterized in that: The feedback camera is arranged above the magnetized droplet movement functional track and is connected with the controller.
3. The automated sample testing system using magnetic droplets as reactant carriers according to claim 1, wherein: The electromagnetic coil is arranged as a circular electromagnetic coil.
4. The automated sample testing system using magnetic droplets as reactant carriers of claim 1, wherein: The electromagnetic coil is arranged as a hexagonal electromagnetic coil, and the hexagonal electromagnetic coils are arranged in an array to form a PCB honeycomb array.
5. The automated sample testing system using magnetic droplets as reactant carriers of claim 1, wherein: It further comprises: The magnetic droplet robot adopts artificial mixed oil containing magnetic nanoparticles.
6. The automated sample testing system using magnetic droplets as reactant carriers of claim 1, wherein: It further comprises: The device shell is provided with a reaction area, and a lifting support is arranged in the reaction area.
7. The method of using an automated sample testing system using magnetic droplets as a carrier for reactants according to any one of claims 1-6, wherein: It comprises the following steps: The sample is placed on the mark point of the waiting area; The reagent is placed on another mark point of the waiting area; The touch LCD man-machine interactive display screen controls the working state of the electromagnetic coil in the combined driving platform, so that the magnetic droplet robot passes through the cutting edge in the waiting area and is split into two magnetic droplet robots; Two magnetic droplet robots are controlled by the touch LCD man-machine interactive display screen to complete the pinocytosis of the sample and the reagent. The two magnet liquid drop robots after endocytosis are respectively controlled by a touch LCD man-machine interactive display screen to enter a reaction area to perform a fusion reaction to generate a result product. The remaining magnet liquid drop robots are controlled by a handle to change the direction of the small magnetic balls above the PCB honeycomb linear array, so that the remaining magnet liquid drop robots follow the small magnetic balls to move to a recycling area.
8. The method of use of claim 7, wherein: Also includes: A feedback camera transmits the motion information of the magnet liquid drop robots to the controller in real time and gives a warning for the motion error state.
Citation Information
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