A fat-reducing composition rich in alpha-amylase inhibitors, and preparation method and application thereof

Abstract

The present invention belongs to the technical field of food production, and specifically relates to a fat-reducing composition rich in α-amylase inhibitors, and a preparation method and application thereof. The raw materials of the fat-reducing composition include: mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan, oligofructose, white kidney bean extract, seaweed powder and chestnut peel extract. In the present invention, sugarcane polyphenols, seaweed powder and chestnut peel extract are added, and a synergistic effect is produced between the three, which significantly improves the effect of controlling sugar and reducing fat.

Description

Technical Field

[0001] The invention belongs to the technical field of food production, and particularly relates to a fat-reducing composition rich in alpha-amylase inhibitors, a preparation method and application thereof. Background Art

[0002] The main cause of obesity is that the body's energy intake exceeds its consumption for a long time, and the excess energy is stored in the form of fat. The body's energy balance is affected by multiple factors such as diet, exercise, endocrine diseases and genetics. The regulation of body weight involves a complex feedback system. The brain, as a central controller, receives and transmits incoming signals and sends outgoing signals to regulate feeding behavior and metabolism. Adipose tissue, as a controlled effector, can metabolize and store nutrients in food.

[0003] Currently, most of the weight management and fat-reducing products on the market reduce the fat and energy of the products themselves, increase the indigestibility of the raw materials used to enhance the feeling of fullness, thereby reducing the user's intake of other foods and reducing calorie intake, thereby achieving a negative balance in the body's energy metabolism and forcing the body to metabolize its own stored fat.

[0004] However, there are many reasons why such traditional weight control strategies are prone to failure, such as: ① The feeling of hunger caused by insufficient energy intake is difficult to offset by increasing the indigestibility of products, and prolonged hunger can easily cause consumers to interrupt dietary intervention. ② The plan to control energy intake requires long-term intervention. During the emptying stage or plateau period, if normal life and social activities are interrupted, high-energy or high-carbohydrate foods may be accidentally eaten, and the intervention effect will be greatly reduced. In addition, most consumers find it difficult to judge the GI value of the food they consume in their normal daily life during the fat loss period, so there is a high probability of accidental ingestion.

[0005] Chinese invention patent application CN106822097A discloses a pharmaceutical composition containing orlistat for weight loss, which contains orlistat and oligosaccharides. Among them, the weight ratio of orlistat to oligosaccharides is 1:0.1-0.9. On the one hand, the pharmaceutical composition containing orlistat and oligosaccharides provided by the invention has a weight loss effect on rats with nutritional obesity comparable to that of orlistat, while the degree of animal oil excretion caused by the pharmaceutical composition provided by the invention in experimental animals is significantly lower than that of orlistat. On the other hand, the results of in vitro dissolution studies found that the dissolution behavior of orlistat in the composition containing orlistat and oligosaccharides disclosed in the invention is better than that of commercially available orlistat capsules. It shows that the pharmaceutical composition containing orlistat provided by the invention reduces its gastrointestinal adverse reactions while maintaining the weight loss effect of the currently commercially available orlistat products, but it will produce a certain dependence on chemical drugs after long-term use.

[0006] Chinese invention patent application CN110269915A discloses a weight loss and lipid-lowering composition and its preparation method. The composition comprises the following raw materials in parts by weight: 10-100 parts of lotus leaves, 1-50 parts of radish seeds, 1-50 parts of hawthorn, 1-50 parts of tuckahoe, 1-50 parts of coix seeds and 1-30 parts of orange peel; 3-30 parts of konjac powder and 3-15 parts of anti-caking agent; the weight loss and lipid-lowering composition of the invention has good effects on simple obesity and postpartum obesity, but the raw materials used in the invention are all traditional Chinese medicines, which are not suitable for specific groups in terms of taste and safety, and have the problem of low bioavailability.

[0007] Chinese invention patent application CN112546133A discloses a Chinese medicine composition for reducing fat and weight, and its preparation method and weight loss preparation, including: rhubarb, Stephania tetrandra, salvia miltiorrhiza, Artemisia capillaris, orientalis, hawthorn, buffalo horn, epimedium, red ganoderma, astragalus, atractylodes, ligusticum chuanxiong, solanum melongena and schizonepeta tenuifolia. The composition and preparation finally prepared have good weight loss effect, simple process and wide application prospect. However, the raw materials used in the invention are all Chinese medicines, which are not suitable for specific groups in terms of taste and safety, and will also produce certain side effects if taken for a long time.

[0008] Therefore, providing an efficient, safe and healthy fat-reducing food is an urgent problem to be solved by those skilled in the art. Summary of the invention

[0009] In view of the deficiencies of the prior art, the present invention provides a fat-reducing composition rich in α-amylase inhibitors, and a preparation method and application thereof. The present invention reduces the metabolism of carbohydrates by the human body by adding a composite water-soluble dietary fiber barrier, and a combination of an inhibitor with the ability to inhibit the activity of amylase and a glucosidase inhibitor, thereby stabilizing blood sugar and inhibiting hormone fluctuations in the body, thereby controlling fat accumulation in the body and reducing weight gain.

[0010] The present invention is achieved through the following technical solutions:

[0011] A fat-reducing composition rich in alpha-amylase inhibitors, wherein the raw materials of the fat-reducing composition include: mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan, oligofructose, white kidney bean extract, seaweed powder, and chestnut peel extract.

[0012] Phaseolin, the active ingredient in white kidney bean extract, is a natural α-amylase inhibitor. Its chemical nature is a glycoprotein with a molecular weight of 24kD and 45KD (also 35KD), which can effectively inhibit the decomposition of starch and excrete it from the body through the gastrointestinal tract. In addition, due to its large molecular weight, kidney bean α-amylase inhibitor does not enter the blood circulation system and does not act on the brain center. It does not suppress appetite while losing weight. There are no side effects when using a high dose, and it has good safety.

[0013] Chestnut peel extract also contains α-amylase inhibitors, which can not only inhibit the activity of amylase and reduce the decomposition and absorption of starch, but also inhibit the activity of glucosidase. By inhibiting the hydrolysis of carbohydrates in the small intestine, it delays the absorption of glucose and other monosaccharides in the digestive tract, thereby achieving the purpose of blood sugar control.

[0014] Sugarcane polyphenols can effectively slow down the decomposition of carbohydrates and the speed at which they enter the blood from the intestines, so as to achieve stable blood sugar levels and insulin secretion in the body; precise control of carbohydrates can not only ensure the energy needs of a healthy body, but also avoid fat accumulation in the body, which helps with body control management.

[0015] Green coffee powder comes from unroasted coffee beans, i.e. green coffee beans. Green coffee powder is rich in chlorogenic acid, which can not only reduce the body's absorption of glucose, lower blood sugar levels, but also reduce fat production. Green coffee powder also has the effect of refreshing the mind and promoting metabolism.

[0016] Seaweed powder comes from various seaweeds, such as kelp and laver. As a brown algae extract, seaweed powder has a strong inhibitory effect on the activity of lipase and amylase, and can significantly reduce body weight and body fat. In addition, seaweed powder is also rich in a variety of minerals and trace elements, which help regulate human metabolism and maintain good health.

[0017] Preferably, the raw materials of the fat-reducing composition include, by weight: 0.1-1 parts of mulberry leaf extract, 0.5-1 parts of sugarcane polyphenols, 0.1-0.5 parts of green coffee powder, 1.3-2 parts of L-arabinose, 0.5-1 parts of galactomannan, 5-10 parts of oligofructose, 2.5-3.5 parts of white kidney bean extract, 1-1.5 parts of seaweed powder, and 0.5-1.5 parts of chestnut peel extract.

[0018] Preferably, the raw materials of the fat-reducing composition further include, by weight: 0.8-1 part of resistant dextrin aqueous solution.

[0019] Further preferably, the mass concentration of the resistant dextrin aqueous solution is 6.75%-8.75%.

[0020] Further preferably, the raw materials of the fat-reducing composition include, by weight: 0.5 parts of mulberry leaf extract, 0.5 parts of sugarcane polyphenols, 0.3 parts of green coffee powder, 1.4 parts of L-arabinose, 0.5 parts of galactomannan, 5 parts of oligofructose, 2.5 parts of white kidney bean extract, 1 part of seaweed powder, 0.5 parts of chestnut peel extract, and 1 part of resistant dextrin aqueous solution with a mass concentration of 7.5%.

[0021] The present invention also relates to a method for preparing the above-mentioned fat-reducing composition, comprising the following steps:

[0022] (1) Mix mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose, and stir to obtain a mixture 1;

[0023] (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, mixing and granulating to obtain mixture 2;

[0024] (3) The mixture 2 is subjected to secondary granulation, discharging, and drying to obtain the fat-reducing composition.

[0025] Preferably, the stirring time in step (1) is 12-20 min, the stirring equipment is a granulator, the stirring speed is 48-60 rpm, and the cutting speed is 750-800 rpm.

[0026] Preferably, the mixing and granulation time in step (2) is 3-5.5 min, the stirring speed during the mixing and granulation process is 120-180 rpm, and the cutting speed is 1280-1500 rpm.

[0027] Preferably, the secondary granulation time in step (3) is 3-5.5 min, the stirring speed is 120-180 rpm, and the cutting speed is 1280-1500 rpm.

[0028] Preferably, the drying conditions in step (3) are: air inlet frequency 7.5 Hz-15 Hz, material temperature 38.5°C-45.5°C, air outlet temperature 30.2°C-44.5°C, and pressure 0.1 MPa-0.4 MPa.

[0029] Preferably, after the material is discharged in step (3), it is sieved through a 55-65 mesh sieve, and the moisture content of the fat-reducing composition is less than 3.0%.

[0030] The present invention also relates to a product for controlling body weight, which comprises the above-mentioned fat-reducing composition.

[0031] Compared with the prior art, the present invention has the following advantages:

[0032] (1) The present invention reduces the degree of digestion by reducing carbohydrate metabolism in the consumer's body, blocking digestion after ingestion, and reducing the activity of related enzymes during digestion. At the same time, it further controls the further metabolism and digestion of starch digestion products downstream of amylase digestion. In this way, the digestion and metabolism of food already ingested by the body are controlled in three steps, thereby reducing intervention failure or body fat rebound caused by daily life such as accidental ingestion of carbohydrates or high-energy foods during the consumer's weight management stage.

[0033] (2) Conventional products on the market that control food starch metabolism mostly work by directly inhibiting the activity of amylase. At the same time, the currently known amylase inhibitors cannot completely inhibit the activity of related enzymes in the body. The present invention controls and reduces the occurrence of starch digestion at the front end. The enzyme activity inhibitor cannot inhibit part of the starch digestion. This part of the starch that enters digestion further reduces the metabolism of the products after enzyme digestion, thereby reducing the available carbohydrates for human digestion and absorption.

[0034] (3) The addition of sugarcane polyphenols, seaweed powder and chestnut peel extract in the present invention produces a synergistic effect among the three, which can significantly improve the effect of controlling sugar and reducing fat.

[0035] (4) In the process of studying the composition, it was found that the wet-mixed composite granulation process had a more obvious effect than the dry-mixed composite. Firstly, the raw materials were encapsulated and granulated in accordance with the metabolic sequence of the human body through the process. Secondly, after the processing by this process, the loss of some of the effective ingredients encapsulated inside during the digestion and metabolism process can be reduced, thereby increasing the sustained effect of the composition. DETAILED DESCRIPTION

[0036] The present invention will be further described in detail below in conjunction with specific examples. The following examples are not intended to limit the present invention but are only intended to illustrate the present invention. The experimental methods used in the following examples are generally based on conventional conditions unless otherwise specified.

[0037] The purchase information of raw materials is shown in Table 1 below.

[0038] Table 1 Raw material purchase information

[0039]

[0040] Example 1

[0041] A fat-reducing composition rich in alpha-amylase inhibitors, comprising the following raw materials, by weight: 1 part of mulberry leaf extract, 1 part of sugarcane polyphenols, 0.5 part of green coffee powder, 2 parts of L-arabinose, 0.5 part of galactomannan, 5 parts of oligofructose, 2.5 parts of white kidney bean extract, 1 part of seaweed powder, 1.5 parts of chestnut peel extract and 1 part of resistant dextrin aqueous solution with a mass concentration of 8.75%.

[0042] The preparation method of the above-mentioned fat-reducing composition is as follows:

[0043] (1) mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose were dry mixed for 13 minutes, stirred at 60 rpm in a granulator, and the cutting speed was 800 rpm to obtain a mixture 1;

[0044] (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, with the peristaltic pump speed at 30 rpm, the granulator stirring speed at 150 rpm, the cutter speed at 1500 rpm, and granulating for 3 minutes to obtain mixture 2;

[0045] (3) The mixture 2 was subjected to secondary granulation, with a stirring speed of 150 rpm, a cutting speed of 1500 rpm, granulation for 3 min, discharging at a discharging speed of 300 rpm, passing through a 60-mesh sieve, and drying (inlet air frequency of 10 Hz, material temperature of 40° C., outlet air temperature of 42° C., and pressure of 0.3 MPa) to obtain the fat-reducing composition.

[0046] Example 2

[0047] A fat-reducing composition rich in alpha-amylase inhibitors, comprising the following raw materials, by weight: 0.5 parts of mulberry leaf extract, 0.5 parts of sugarcane polyphenols, 0.3 parts of green coffee powder, 1.4 parts of L-arabinose, 0.5 parts of galactomannan, 5 parts of oligofructose, 2.5 parts of white kidney bean extract, 1 part of seaweed powder, 0.5 parts of chestnut peel extract, and 1 part of resistant dextrin aqueous solution with a mass concentration of 7.5%.

[0048] The preparation method of the above-mentioned fat-reducing composition is as follows:

[0049] (1) mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose were dry mixed for 15 minutes, stirred at 60 rpm in a granulator and at a cutting speed of 800 rpm to obtain a mixture 1;

[0050] (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, with the peristaltic pump speed at 30 rpm, the granulator stirring speed at 150 rpm, the cutter speed at 1500 rpm, and granulating for 3 minutes to obtain mixture 2;

[0051] (3) The mixture 2 was subjected to secondary granulation, with a stirring speed of 150 rpm, a cutting speed of 1500 rpm, granulation for 3 min, discharging at a discharging speed of 300 rpm, passing through a 60-mesh sieve, and drying (inlet air frequency of 7.5 Hz, material temperature of 38.5° C., outlet air temperature of 40.2° C., and pressure of 0.2 MPa) to obtain the fat-reducing composition.

[0052] Example 3

[0053] A fat-reducing composition rich in alpha-amylase inhibitors, comprising the following raw materials, by weight: 0.1 parts of mulberry leaf extract, 0.8 parts of sugarcane polyphenols, 0.1 parts of green coffee powder, 1.3 parts of L-arabinose, 1 part of galactomannan, 10 parts of oligofructose, 3.5 parts of white kidney bean extract, 1.5 parts of seaweed powder, 1.0 part of chestnut peel extract and 1 part of resistant dextrin aqueous solution with a mass concentration of 6.75%.

[0054] The preparation method of the above-mentioned fat-reducing composition is as follows:

[0055] (1) mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose were dry mixed for 12 minutes, stirred at 60 rpm in a granulator, and the cutting speed was 800 rpm to obtain a mixture 1;

[0056] (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, with the peristaltic pump speed at 30 rpm, the granulator stirring speed at 150 rpm, the cutter speed at 1500 rpm, and granulating for 3 minutes to obtain mixture 2;

[0057] (3) The mixture 2 was subjected to secondary granulation, with a stirring speed of 180 rpm, a cutting speed of 1500 rpm, granulation for 3 min, discharging, a discharging speed of 300 rpm, passing through a 60-mesh sieve, and drying (inlet air frequency of 12 Hz, material temperature of 41° C., outlet air temperature of 44.5° C., and a pressure of 0.4 MPa) to obtain the fat-reducing composition.

[0058] Example 4

[0059] A fat-reducing composition rich in alpha-amylase inhibitors, comprising the following raw materials, by weight: 0.5 parts of mulberry leaf extract, 0.8 parts of sugarcane polyphenols, 0.5 parts of green coffee powder, 1.5 parts of L-arabinose, 0.8 parts of galactomannan, 7 parts of oligofructose, 3 parts of white kidney bean extract, 1.2 parts of seaweed powder, 1.0 parts of chestnut peel extract and 1 part of resistant dextrin aqueous solution with a mass concentration of 7.25%.

[0060] The preparation method of the above-mentioned fat-reducing composition is as follows:

[0061] (1) mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose were dry mixed for 18 minutes, stirred at 48 rpm in a granulator, and the cutting speed was 750 rpm to obtain a mixture 1;

[0062] (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, with the peristaltic pump speed at 30 rpm, the granulator stirring speed at 120 rpm, the cutter speed at 1280 rpm, and granulation for 5.5 minutes to obtain mixture 2;

[0063] (3) The mixture 2 was subjected to secondary granulation, with a stirring speed of 120 rpm, a cutting speed of 1280 rpm, granulation for 5.5 min, discharging, a granulation speed of 160 rpm, passing through a 60-mesh sieve, and drying (inlet air frequency of 15 Hz, material temperature of 38.5° C., outlet air temperature of 30.2° C., and pressure of 0.1 MPa) to obtain the fat-reducing composition.

[0064] Comparative Example 1

[0065] A fat-reducing composition rich in alpha-amylase inhibitors, wherein the raw materials are the same as those in Example 2.

[0066] The preparation method is:

[0067] (1) dry-mixing mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan, white kidney bean extract, seaweed powder, chestnut peel extract and oligofructose for 15 minutes, with the stirring speed of the granulator being 60 rpm and the cutting speed being 800 rpm to obtain a mixture 1;

[0068] (2) Add the resistant dextrin aqueous solution to the mixture 1, the peristaltic pump speed is 30 rpm, the granulator stirring speed is 150 rpm, the cutter speed is 1500 rpm, granulation is carried out for 3 minutes, the material is discharged at a granulation speed of 300 rpm, passed through a 60-mesh sieve, and dried (inlet frequency 10 Hz, material temperature 40°C, outlet temperature 42°C, pressure 0.3 MPa), to obtain the fat-reducing composition.

[0069] Comparative Examples 2-5

[0070] The only difference between Comparative Examples 2-5 and Example 2 is that the added amounts of sugarcane polyphenols, seaweed powder and chestnut peel extract in the fat-reducing composition are different.

[0071] The weight percentages of seaweed powder, sugarcane polyphenols and chestnut peel extract in the fat-reducing compositions of Comparative Examples 2-5 are shown in Table 2. The fat-reducing compositions of Comparative Examples 2-5 are prepared in the same manner as in Example 2.

[0072] Table 2 Weight percentage of some raw materials in the fat-reducing composition of Comparative Examples 2-5

[0073]

[0074] Effect test

[0075] 1. Glycemic index evaluation

[0076] Through human experiment, after taking 50g of rice and 5g of the fat-reducing composition of Examples 1-4 and Comparative Examples 1-5 of the present invention, the effect of inhibiting blood sugar rise after meal was verified. Among them, healthy people who took 50g of rice directly on an empty stomach were used as the reference group. There were 12 volunteers in each group, and the results were averaged.

[0077] The test method is based on ISO26642:2010 "Food products-Determination of the glycaemic index (GI) and recommendation for food classification" and WS / T 652-2019 "Method for determination of the glycaemic index of food".

[0078] Glycemic index (GI): It is a property of carbohydrates in food, which refers to the ability of digestible carbohydrates in food to cause blood sugar in the human body to rise. Incremental area under the curve (IAUC): The area under the curve above the fasting blood sugar level.

[0079] GI calculation method: With time as the horizontal axis and blood glucose value at each time point as the vertical axis, a blood glucose response curve is made, and the area under the blood glucose curve is calculated. The GI value of the test food is calculated with the GI value of glucose reference food as 100 (the GI value of white bread is 71). I mean .

[0080] I mean = test food IAUC / reference food glucose IAUC × 100

[0081] The comparison results of IAUC and GI values ​​of Examples 1-4 and Comparative Examples 1-5 are shown in Table 3.

[0082] Table 3 Comparison results of IAUC and GI values

[0083]

[0084] In the implementation process of the present invention, it is preferred to take 0.5 parts of mulberry leaf extract, 0.5 parts of sugarcane polyphenols, 0.3 parts of green coffee powder, 1.4 parts of L-arabinose, 0.5 parts of galactomannan, 5 parts of oligofructose, 2.5 parts of white kidney bean extract, 1 part of seaweed powder, 0.5 parts of chestnut peel extract and 1 part of 7.5% concentration resistant dextrin, and after secondary embedding and granulation, take it with meals to achieve the most stable blood sugar fluctuation in the human body and the best effect.

[0085] 2. Mouse fat reduction experiment

[0086] Experimental animals: SPF grade Kunming mice, weighing 20-25g, were used for 3 days of adaptation observation. The animals were allowed to drink water and eat freely. The temperature was (20±2)℃, the humidity was (60±5)%, and the light cycle was 12h.

[0087] Obesity model was established: mice were randomly divided into 2 groups, 10 normal control group and 90 model group. The normal control group was always fed with basal feed (maintenance feed for experimental mice), and the model group was fed with high-fat feed (45% fat energy high-fat feed) for 2 weeks. Then, 70 heavier obese mice (obesity-resistant mice were removed) were selected according to their body weight and fed with high-fat feed for another 2 weeks for subsequent experiments.

[0088] The model group mice were randomly divided into 7 groups, each with 10 mice, of which 1 group was the model control group, and the other 6 groups were Example 2 group and Comparative Example 1-5 groups, respectively. After modeling, the normal control group and the model control group were given basal feed, and Example 2 group and Comparative Example 1-5 groups were given fat-reducing feed (60% basal feed + 40% fat-reducing composition), respectively, for 5 consecutive weeks.

[0089] The weight and food intake of each group of mice were recorded every three days. After the experiment, the TC value, TG value, FFA value, final weight and fat index of different mice were tested. The test results are shown in Table 4.

[0090] Among them, blood test: blood was collected from the eyelids, and the blood was centrifuged (3000rmp, 4℃, 5min), and the supernatant was taken, that is, serum, and serum TG, TC, and FFA were measured. Body fat index measurement: After the experiment, the animals were killed, and the liver, perirenal adipose tissue, and testicular (ovarian) perifacial adipose tissue were removed and weighed. The ratio of perirenal adipose tissue and testicular (ovarian) perifacial adipose tissue to body weight, that is, fat body ratio, was calculated respectively.

[0091] Table 4 Fat reduction test results

[0092]

[0093] Note: Different letters in the same column indicate significant statistical differences between the corresponding groups, p < 0.05.

[0094] The above detailed description is a specific description of one feasible embodiment of the present invention. The embodiment is not intended to limit the patent scope of the present invention. Any equivalent implementation or modification that does not deviate from the present invention should be included in the scope of the technical solution of the present invention.

Claims

1. A fat-reducing composition rich in α-amylase inhibitors, characterized in that: The raw materials of the fat-reducing composition are as follows: 0.1-1 parts of mulberry leaf extract, 0.5-1 parts of sugarcane polyphenols, 0.1-0.5 parts of green coffee powder, 1.3-2 parts of L-arabinose, 0.5-1 parts of galactomannan, 5-10 parts of oligofructose, 2.5-3.5 parts of white kidney bean extract, 1-1.5 parts of seaweed powder, 0.5-1.5 parts of chestnut peel extract and 0.8-1 parts of resistant dextrin aqueous solution. The preparation method of the above-mentioned fat-reducing composition comprises the following steps: (1) Mix mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose, and stir to obtain a mixture 1; (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, mixing and granulating to obtain mixture 2; (3) The mixture 2 is subjected to secondary granulation, discharging, and drying to obtain the fat-reducing composition.

2. The fat-reducing composition according to claim 1, characterized in that: The mass concentration of the resistant dextrin aqueous solution is 6.75%-8.75%.

3. A method for preparing the fat-reducing composition according to any one of claims 1 to 2, characterized in that: The following steps are involved: (1) Mix mulberry leaf extract, sugarcane polyphenols, green coffee powder, L-arabinose, galactomannan and oligofructose, and stir to obtain a mixture 1; (2) adding white kidney bean extract, seaweed powder, chestnut peel extract and resistant dextrin aqueous solution to mixture 1, mixing and granulating to obtain mixture 2; (3) The mixture 2 is subjected to secondary granulation, discharging, and drying to obtain the fat-reducing composition.

4. The preparation method according to claim 3, characterized in that: The stirring time in step (1) is 12-20 minutes, the stirring equipment is a granulator, the stirring speed is 48-60 rpm, and the cutting speed is 750-800 rpm.

5. The preparation method according to claim 3, characterized in that: The mixing and granulation time in step (2) is 3-5.5 min, the stirring speed during the mixing and granulation process is 120-180 rpm, and the cutting speed is 1280-1500 rpm.

6. The preparation method according to claim 3, characterized in that: The secondary granulation time in step (3) is 3-5.5 min, the stirring speed is 120-180 rpm, and the cutting speed is 1280-1500 rpm.

7. The preparation method according to claim 3, characterized in that: The drying conditions in step (3) are: air inlet frequency 7.5 Hz-15 Hz, material temperature 38.5°C-45.5°C, air outlet temperature 30.2°C-44.5°C, and pressure 0.1 MPa-0.4 MPa.

8. The preparation method according to claim 3, characterized in that: After the material is discharged in step (3), the step of passing the material through a 55-65 mesh sieve is also included, and the moisture content of the fat-reducing composition is less than 3.0%.

9. Use of the fat-reducing composition according to any one of claims 1 to 2 in the preparation of a product for controlling body weight.

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