A composite physical field adaptive ablation system and device based on integrated single needle

Abstract

The present invention is applicable to the field of smart medical treatment of medical devices, and provides a composite physical field adaptive ablation system and device based on an integrated single needle. In this embodiment, the system integrates a variety of energy generating devices and controls them through ablation treatment timing functions, and the integrated electrode needle includes electrode groups corresponding to each energy generating device. During the ablation operation, the ablation area is treated and monitored by a preset ablation method. When it is determined that the ablation method needs to be adjusted, the ablation treatment timing function is adaptively adjusted so that the adjusted energy generating device generates energy and emits it through the electrode group corresponding to the energy on the integrated electrode needle. This achieves the adaptive emission of multiple physical field energies through an integrated single electrode needle during the ablation operation, solving the problem of parallel needle operation and the risk of hemostasis / implantation.

Description

Technical Field

[0001] The present application relates to the field of smart medical treatment using medical devices, and in particular to a composite physical field adaptive ablation system and device based on an integrated single needle. Background Art

[0002] Tumors, especially malignant tumors, are important diseases that endanger human health. In recent years, the number of new cases and deaths of tumors in my country and around the world has continued to rise. The high incidence trend highlights the necessity and urgency of developing innovative technologies for minimally invasive tumor treatment. The incomplete treatment of traditional ablation and the easy recurrence after surgery are major factors limiting the promotion of ablation procedures. Pulsed electric field is an emerging minimally invasive tumor ablation treatment method in recent years. It applies local short pulse high voltage to the tumor target tissue to form permanent perforations on the cell membrane and / or internal organelle membrane, change cell permeability and electrical properties, and thus lead to cell apoptosis. Compared with traditional temperature-based microwave, radiofrequency, freezing and other cold and hot ablation technologies that indiscriminately kill tumors, nerves and blood vessels and other tissues, pulsed electric fields have the characteristics of higher tissue and organ specific ablation or selective ablation, and have higher ablation treatment accuracy, safety and effectiveness.

[0003] On the other hand, however, pulsed electric field tumor ablation treatment technology also faces shortcomings. First, the problem of difficulty in parallel operation of two needles. At present, during pulsed electric field tumor ablation treatment, a high-voltage electric field is generated between two electrode needles, one positive and one negative, to form an ablation treatment area. The two inserted electrodes need to be as parallel as possible to achieve the best treatment range and effect. This requires high practical operation experience / level of clinical physicians and is difficult. It is difficult to ensure that the two electrodes are parallel to each other during actual operation, which affects the actual ablation effect of pulsed electric field. Secondly, the risk of needle tract bleeding and tumor implantation and spread. Although the non-thermal ablation characteristics of pulsed electric fields improve the accuracy, effectiveness and safety of ablation, they do not have the coagulation / hemostasis function of traditional thermal ablation. There is a risk of bleeding in patients and coagulation problems during ablation surgery; in addition, there may be residual live cells in the ablation needle during pulsed electric field ablation, and the risk of cancer cell spread and implantation in the needle tract area when the needle is withdrawn cannot be completely ignored. Summary of the invention

[0004] In view of this, the present application provides a composite physical field adaptive ablation system and device based on an integrated single needle, which adaptively emits multiple physical field energies through an integrated single electrode needle, while solving the parallel needle operation difficulties and hemostasis / implantation risk problems.

[0005] The first aspect of the present application provides a composite physical field adaptive ablation system based on an integrated single needle, the system comprising an integrated single needle module, a composite physical field energy generation module, an adaptive control module and an ablation parameter determination module;

[0006] The integrated single needle module includes an integrated electrode needle, and the integrated electrode needle includes a plurality of different types of electrode groups, which are used to emit different energies generated by the composite physical field energy generation module to the target ablation area, so as to achieve precise ablation of the composite physical field;

[0007] The composite physical field energy generation module is used to determine the target ablation method through the ablation treatment timing function, and determine the target energy type according to the target ablation method, generate energy according to the ablation parameters corresponding to the target energy type, and transmit the energy to the target ablation area through the integrated electrode for ablation treatment;

[0008] The adaptive control module is used to monitor the target ablation area through real-time images and adjust the ablation treatment timing function according to the monitoring results;

[0009] The ablation parameter determination module is used to determine the ablation parameters of the target ablation method through the preoperative information and intraoperative images of the target patient, and send the ablation parameters to the composite physical field energy generation module so that the composite physical field energy generation module generates energy according to the ablation parameters.

[0010] Optionally, the different types of electrode groups include radio frequency electrode groups and pulsed electric field electrode groups;

[0011] The method for determining a target ablation through an ablation treatment timing function includes:

[0012] According to the type of electrode group, the ablation treatment timing function includes a radiofrequency ablation timing function and a pulsed electric field ablation timing function, and the radiofrequency ablation timing function is determined to be , the pulse electric field ablation timing function is ;

[0013] Determine the and When the value of When the radio frequency electrode group transmits energy, , emitting energy through the pulsed electric field electrode group.

[0014] Optionally, the composite physical field energy generation module includes a power supply module, a control module, a plurality of different energy driving modules, a plurality of different energy generation modules, an output switching module and an energy output interface;

[0015] The power supply module includes an AC-DC conversion module and a DC-DC conversion module, which are used to perform power conversion and provide the required power for other modules;

[0016] The control module is used to provide the required driving signal for the energy driving module, thereby generating the driving signal required by the energy generating module, and providing corresponding interaction information between different energy generating modules, collecting feedback signals and sending them to the adaptive control module;

[0017] The output switching module and the energy output interface switch the energy and output it according to the ablation timing function.

[0018] Optionally, the system further includes an image navigation function module;

[0019] The image navigation function module is used to monitor the surrounding area of ​​the integrated electrode needle in real time when performing needle advancement and withdrawal operations through real-time images, adjust the needle advancement and withdrawal path according to the real-time images, and navigate according to the adjusted needle advancement and withdrawal path.

[0020] Optionally, the system further includes a simulation module;

[0021] The simulation module is used for performing ablation simulation according to the ablation parameters before the composite physical field energy generation module generates energy according to the ablation parameters, and determining whether the simulated ablation area generated by the ablation simulation meets expectations;

[0022] When the conditions are met, informing the composite physical field energy generation module to send energy according to the ablation parameters;

[0023] When it does not meet the requirements, the ablation parameters are adjusted, and ablation simulation is performed again according to the adjusted ablation parameters, until the simulated ablation area meets expectations, and energy is sent according to the adjusted ablation parameters through the composite physical field energy generation module.

[0024] The second aspect of the present application provides a composite physical field adaptive ablation device based on an integrated single needle, the device comprising:

[0025] an ablation parameter determination unit, used to determine ablation parameters for ablation treatment based on preoperative information and intraoperative images of a target patient;

[0026] An adaptive control unit, used to monitor the target ablation area through real-time images and adjust the ablation treatment timing function according to the monitoring results;

[0027] A composite physical field energy generating unit is used to determine a target ablation method through the ablation treatment timing function, determine a target energy type according to the target ablation method, generate energy according to ablation parameters corresponding to the target energy type, and transmit the energy to the target ablation area through an integrated electrode for ablation treatment, wherein the integrated electrode needle includes several electrode groups of different types.

[0028] Optionally, the different types of electrode groups in the composite physical field energy generating unit include a radio frequency electrode group and a pulsed electric field electrode group;

[0029] The method for determining a target ablation through an ablation treatment timing function includes:

[0030] According to the type of electrode group, the ablation treatment timing function includes a radiofrequency ablation timing function and a pulsed electric field ablation timing function, and the radiofrequency ablation timing function is determined to be , the pulse electric field ablation timing function is ;

[0031] Determine the and When the value of When the radio frequency electrode group transmits energy, , emitting energy through the pulsed electric field electrode group.

[0032] Optionally, the composite physical field energy generation unit includes a power supply module, a control module, a plurality of different energy driving modules, a plurality of different energy generation modules, an output switching module and an energy output interface;

[0033] The power supply module includes an AC-DC conversion module and a DC-DC conversion module, which are used to perform power conversion and provide the required power for other modules;

[0034] The control module is used to provide the required driving signal for the energy driving module, thereby generating the driving signal required by the energy generating module, and providing corresponding interaction information between different energy generating modules, collecting feedback signals and sending them to the adaptive control module;

[0035] The output switching module and the energy output interface switch the energy and output it according to the ablation timing function.

[0036] Optionally, the device further comprises:

[0037] The image navigation function unit is used to monitor the surrounding area of ​​the integrated electrode needle in real time when performing the needle advancement and withdrawal operation through real-time images, adjust the needle advancement and withdrawal path according to the real-time images, and navigate according to the adjusted needle advancement and withdrawal path.

[0038] Optionally, the device further comprises:

[0039] A simulation unit, configured to perform ablation simulation according to the ablation parameters corresponding to the target energy type before generating energy according to the ablation parameters, and determine whether the simulated ablation area generated by the ablation simulation meets expectations;

[0040] When the conditions are met, informing the composite physical field energy generation module to send energy according to the ablation parameters;

[0041] When it does not meet the requirements, the ablation parameters are adjusted, and ablation simulation is performed again according to the adjusted ablation parameters, until the simulated ablation area meets expectations, and energy is sent according to the adjusted ablation parameters through the composite physical field energy generation module.

[0042] In the embodiment provided in the present application, the system integrates a variety of energy generating devices and controls them through ablation treatment timing functions, and the integrated electrode needle includes electrode groups corresponding to each energy generating device. During the ablation procedure, the ablation area is treated and monitored by a preset ablation method. When it is determined that the ablation method needs to be adjusted, the ablation treatment timing function is adaptively adjusted so that the adjusted energy generating device generates energy and emits it through the electrode group corresponding to the energy on the integrated electrode needle. This realizes the adaptive emission of multiple physical field energies through an integrated single electrode needle during the ablation procedure, solving the parallel needle operation problem and hemostasis / implantation risk problems in ablation treatment surgery. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 A system module diagram provided for an embodiment of the present application;

[0044] Figure 2 A schematic diagram of the structure of an integrated single needle provided in an embodiment of the present application;

[0045] Figure 3 A schematic diagram of the structure of the composite physical field energy generation module provided in the embodiment of the present application

[0046] Figure 4 A schematic diagram of timing control of the adaptive ablation method provided in an embodiment of the present application;

[0047] Figure 5 Another timing control schematic diagram of the adaptive ablation method provided in an embodiment of the present application;

[0048] Figure 6 A structural diagram of a device provided in an embodiment of the present application;

[0049] Figure 7 A schematic diagram of the internal structure of a computer device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0050] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, the same numbers in different drawings represent the same or similar elements unless otherwise indicated. The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present application. Instead, they are merely examples of devices and methods consistent with some aspects of the present application as detailed in the appended claims.

[0051] The terms used in this application are for the purpose of describing specific embodiments only and are not intended to limit this application. The singular forms of "a", "said" and "the" used in this application and the appended claims are also intended to include plural forms unless the context clearly indicates other meanings. It should also be understood that the term "and / or" used herein refers to and includes any or all possible combinations of one or more associated listed items.

[0052] It should be understood that although the terms first, second, third, etc. may be used in the present application to describe various information, these information should not be limited to these terms. These terms are only used to distinguish the same type of information from each other. For example, without departing from the scope of the present application, the first information may also be referred to as the second information, and similarly, the second information may also be referred to as the first information. Depending on the context, the word "if" as used herein may be interpreted as "at the time of" or "when" or "in response to determining".

[0053] The present application provides a composite physical field adaptive ablation system based on an integrated single needle to solve the problem of parallel needle operation and hemostasis / implantation risk during ablation treatment surgery.

[0054] The technical solution of the present application is described in detail below with specific embodiments. These specific embodiments can be combined with each other, and the same or similar concepts or processes may not be described in detail in some embodiments.

[0055] like Figure 1 As shown, it is a module diagram of a composite physical field adaptive ablation system based on an integrated single needle provided by the present application. The system includes an integrated single needle module, a composite physical field energy generation module, an adaptive control module and an ablation parameter determination module.

[0056] The functions of each module are described below:

[0057] 1. Integrated single needle module. This module includes an integrated electrode needle, which includes several different types of electrode groups, and is used to transmit different energies generated by the composite physical field energy generation module to the target ablation area to achieve precise ablation of the composite physical field.

[0058] For example, Figure 2 As shown, the electrode needle includes 4 electrodes, which are connected to the adaptive control module through a connecting line. Electrodes 1 and 3 can form a pair of radio frequency electrode groups, electrodes 2 and 4 can form a pair of pulsed electric field electrode groups, and temperature sensors or pressure sensors, as well as other thermal ablation energy forms such as microwaves, can also be installed on the electrodes. The electrode needle can be used to transmit radio frequency ablation energy or pulsed electric field ablation energy to the target area. Thus, thermal field-pulsed electric field double-check ablation is achieved through a single electrode needle.

[0059] 2. Composite physical field energy generation module. This module is used to determine the target ablation method through the ablation treatment timing function, determine the target energy type according to the target ablation method, generate energy according to the ablation parameters corresponding to the target energy type, and transmit the energy to the target ablation area through the integrated electrode for ablation treatment.

[0060] In this module, an ablation therapy timing function can be set for each energy generating device integrated in this solution, and different function values ​​can be set for each energy generating device. For example, when the ablation therapy timing function value is 1, energy is generated by energy generating device A, and then the electrode group corresponding to the energy is emitted to the target area through the integrated electrode needle. When the ablation therapy timing function value is 2, energy is generated by energy generating device B; when the ablation therapy timing function value is 3, energy is generated by energy generating device C.

[0061] In another embodiment, different ablation treatment timing functions can be set for different energy generating devices, and the corresponding energy generating devices can be turned on or off by each ablation treatment timing function. For example, when the system integrates a radio frequency energy generating device and a pulsed electric field energy generating device, a radio frequency electrode group and a pulsed electric field electrode group are configured on the integrated electrode needle. According to the type of electrode group, it is determined that the ablation treatment timing function includes a radio frequency ablation timing function and a pulsed electric field ablation timing function, and the radio frequency ablation timing function is determined to be , used to control the RF energy generating device. The pulse electric field ablation timing function is , used to control the pulse electric field energy generating device. During ablation therapy, real-time detection and When When the radio frequency energy generating device is turned on, the radio frequency electrode group on the electrode needle transmits energy. , then the pulse electric field energy generating device is controlled to start, and the pulse electric field electrode group on the electrode needle emits energy. This makes it possible to control the ablation treatment process. and The value of can be used to switch the ablation method.

[0062] In another embodiment, the composite physical field energy generation module includes a power supply module, a control module, a plurality of different energy driving modules, a plurality of different energy generation modules, an output switching module and an energy output interface;

[0063] The power supply module includes an AC-DC conversion module and a DC-DC conversion module, which are used to perform power conversion and provide the required power for other modules;

[0064] The control module is used to provide the required driving signal for the energy driving module, thereby generating the driving signal required by the energy generating module, and providing corresponding interactive information between different energy generating modules, collecting feedback signals and sending them to the adaptive control module;

[0065] The output switching module and the energy output interface switch the energy and output it according to the ablation timing function.

[0066] In this embodiment, taking pulse electric field and radio frequency energy composite ablation as an example, the schematic diagram of the composite physical field energy generation module is as follows: Figure 3 As shown. The power module provides the power required by the control module, RF drive module, pulse drive module, RF energy module, and pulse energy module. The control module provides the required drive signals for the RF drive module and the pulse drive module, thereby generating the drive signals required by the two energy modules. At the same time, it provides the corresponding interactive information for the RF energy module and the pulse energy module, collects feedback signals and sends them to the adaptive control module, and obtains command information from the adaptive control module to achieve the ideal capacity output state. The output switching module and the energy output port adjust the output mode in real time according to the ablation timing function to meet the target ablation energy needs.

[0067] 3. Adaptive control module: This module is used to monitor the target ablation area through real-time images and adjust the ablation treatment timing function according to the monitoring results.

[0068] In this embodiment, the ablation treatment timing function can be adjusted according to different scenarios, thereby achieving switching of ablation methods.

[0069] Scenario 1: After pulsed electric field ablation, thermal ablation is performed on the needle track to prevent the spread of cancer cells.

[0070] Step 1: The adaptive control module keeps the RF energy generating device turned off. Keep the RF electrode group disconnected. Turn on the pulsed electric field energy generator. , and connect the pulsed electric field electrode group.

[0071] Step 2: Perform pulsed electric field ablation on the target ablation area until the pulsed electric field ablation is completed.

[0072] Step 3: The adaptive control module turns off the pulse electric field energy generating device, i.e. , disconnect the pulsed electric field electrode group. Turn on the RF energy generating device, i.e. , and connect the radio frequency electrode group.

[0073] Step 4: Thermal ablation of the needle tract until the ablation is complete. The timing control diagram is shown in the figure. Figure 4 shown.

[0074] In this scenario, after pulsed electric field ablation treatment of the target area, thermal ablation of the needle track is performed through a pulsed electric-thermal composite field, thus avoiding the spread and implantation of cancer cells.

[0075] Scenario 2: Severe bleeding occurs suddenly during pulsed electric field ablation and emergency hemostasis is performed.

[0076] Step 1: The adaptive control module keeps the RF energy generating device turned off. Keep the RF electrode group disconnected. Turn on the pulsed electric field energy generator. , and connect the pulsed electric field electrode group.

[0077] Step 2: Perform pulsed electric field ablation on the target ablation tissue and conduct real-time image monitoring during the ablation process. If sudden bleeding is found, proceed to step 3; if there is no bleeding, continue to perform pulsed electric field ablation on the target ablation tissue until the ablation is completed.

[0078] Step 3: The adaptive control module turns off the pulse electric field energy generating device, i.e. , disconnect the pulsed electric field electrode group. Turn on the RF energy generating device, i.e. , and connect the radio frequency electrode group.

[0079] Step 4: Perform thermal coagulation hemostasis on the bleeding site, and perform real-time video monitoring during the thermal coagulation hemostasis process. If the hemostasis is successful, proceed to step 5; otherwise, continue to perform thermal coagulation hemostasis on the bleeding site until the hemostasis is successful.

[0080] Step 5: The adaptive control module keeps the RF energy generating device turned off. Keep the RF electrode group disconnected. Turn on the pulsed electric field energy generator. , and connect the pulse electric field electrode group. Enter step 2, the timing control diagram is as follows Figure 5 shown.

[0081] In this scenario, when bleeding occurs during pulsed electric field ablation treatment in the target area, the ablation method can be quickly adjusted through the ablation treatment timing function to stop the bleeding, thereby improving the safety of the ablation treatment operation.

[0082] 4. Ablation parameter determination module. This module is used to determine the ablation parameters of the target ablation method through the preoperative information and intraoperative images of the target patient. For example, when the target ablation method is pulsed electric field ablation, the ablation parameters are voltage, pulse width, number of pulses, etc. When the target ablation method is radiofrequency ablation, the ablation parameters are current power, operating frequency, etc. After determining the ablation parameters, the ablation parameters are sent to the composite physical field energy generation module, so that the composite physical field energy generation module controls each ablation energy generation device to generate energy according to the ablation parameters.

[0083] So far, completed Figure 1 Description of the system modules shown.

[0084] In the above embodiment, the system integrates a variety of ablation energy generating devices and controls them through ablation treatment timing functions, and the integrated electrode needle includes electrode groups corresponding to each energy generating device. During the ablation procedure, the ablation area is treated and monitored by a preset ablation method. When it is determined that the ablation method needs to be adjusted, the ablation treatment timing function is adaptively adjusted so that the adjusted energy generating device generates energy and emits it through the electrode group corresponding to the energy on the integrated electrode needle. This realizes the adaptive emission of multiple physical field energies through an integrated single electrode needle during the ablation procedure, solving the problem of parallel needle operation and the risk of hemostasis / implantation.

[0085] In another embodiment, the above system further includes an image navigation function module;

[0086] This module is used to monitor the surrounding area of ​​the integrated electrode needle in real time when performing needle advancement and withdrawal operations through real-time images, adjust the needle advancement and withdrawal path according to the real-time images, and navigate according to the adjusted needle advancement and withdrawal path.

[0087] In another embodiment, the above system further comprises a simulation module;

[0088] This module is used for performing ablation simulation according to the ablation parameters before the composite physical field energy generation module generates energy according to the ablation parameters, and determining whether the simulated ablation area generated by the ablation simulation meets expectations;

[0089] When the conditions are met, informing the composite physical field energy generation module to send energy according to the ablation parameters;

[0090] When it does not meet the requirements, the ablation parameters are adjusted, and ablation simulation is performed again according to the adjusted ablation parameters, until the simulated ablation area meets expectations, and energy is sent according to the adjusted ablation parameters through the composite physical field energy generation module.

[0091] In this module, taking the pulse electric field as an example, the simulation process is as follows:

[0092] pass ,and Determine the electric field strength E of the area to be treated, where σ is the conductivity, which can be expressed as Indicates that conductivity is related to temperature and external ablation electric field, and the specific value can be measured in real time by sensors. U is the electric potential, and the positive electrode boundary potential of U is the preset value U0. U0 can be set to different values ​​according to different ablation devices, and the negative electrode boundary potential is grounded 0V.

[0093] The main parameters to be solved in the above equations, the electric field intensity E and the electric potential U, can be solved by COMSOL finite element software or other similar software.

[0094] After the electric field strength E is determined, the area where the electric field strength is not less than the preset ablation threshold field strength can be determined as the estimated pulse electric field ablation area. The area is determined as the simulated pulse electric field ablation area. is the preset ablation threshold field strength, is the time parameter, It is the three-dimensional spatial parameter of the entire area to be treated.

[0095] After the simulated pulse electric field ablation area is determined, it is compared with the preset ablation range in the preoperative treatment plan. If the repetition rate of the two is less than the preset value, it means that the effect of ablation treatment using the above treatment parameters does not meet expectations and needs to be adjusted and re-estimated and compared. When the repetition rate exceeds the preset value, the step of performing pulse electric field ablation treatment on the target patient according to the treatment parameters is executed.

[0096] In this module, the treatment parameters are simulated before ablation therapy, so that the best treatment parameters can be determined before ablation therapy, thereby improving the accuracy and safety of ablation surgery.

[0097] like Figure 6 As shown, the present application also provides a composite physical field adaptive ablation device based on an integrated single needle, the device comprising:

[0098] an ablation parameter determination unit 601, configured to determine ablation parameters for ablation treatment based on preoperative information and intraoperative images of a target patient;

[0099] An adaptive control unit 602 is used to monitor the target ablation area through real-time images and adjust the ablation treatment timing function according to the monitoring results;

[0100] The composite physical field energy generating unit 603 is used to determine the target ablation method through the ablation treatment timing function, determine the target energy type according to the target ablation method, generate energy according to the ablation parameters corresponding to the target energy type, and transmit the energy to the target ablation area through the integrated electrode for ablation treatment, wherein the integrated electrode needle includes several different types of electrode groups.

[0101] In another embodiment, the different types of electrode groups in the composite physical field energy generating unit include a radio frequency electrode group and a pulsed electric field electrode group;

[0102] The method for determining a target ablation through an ablation treatment timing function includes:

[0103] According to the type of electrode group, the ablation treatment timing function includes a radiofrequency ablation timing function and a pulsed electric field ablation timing function, and the radiofrequency ablation timing function is determined to be , the pulse electric field ablation timing function is ;

[0104] Determine the and When the value of When the radio frequency electrode group transmits energy, , emitting energy through the pulsed electric field electrode group.

[0105] In another embodiment, the composite physical field energy generation unit includes a power supply module, a control module, a plurality of different energy driving modules, a plurality of different energy generating modules, an output switching module and an energy output interface;

[0106] The power supply module includes an AC-DC conversion module and a DC-DC conversion module, which are used to perform power conversion and provide the required power for other modules;

[0107] The control module is used to provide the required driving signal for the energy driving module, thereby generating the driving signal required by the energy generating module, and providing corresponding interaction information between different energy generating modules, collecting feedback signals and sending them to the adaptive control module;

[0108] The output switching module and the energy output interface switch the energy and output it according to the ablation timing function.

[0109] In another embodiment, the apparatus further comprises:

[0110] The image navigation function unit 604 is used to monitor the surrounding area of ​​the integrated electrode needle in real time when performing the needle advancement and withdrawal operation through real-time images, adjust the needle advancement and withdrawal path according to the real-time images, and navigate according to the adjusted needle advancement and withdrawal path.

[0111] In another embodiment, the apparatus further comprises:

[0112] A simulation unit 605 is used for performing ablation simulation according to the ablation parameters before generating energy according to the ablation parameters corresponding to the target energy type, and determining whether the simulated ablation area generated by the ablation simulation meets expectations;

[0113] When the conditions are met, informing the composite physical field energy generation module to send energy according to the ablation parameters;

[0114] When it does not meet the requirements, the ablation parameters are adjusted, and ablation simulation is performed again according to the adjusted ablation parameters, until the simulated ablation area meets expectations, and energy is sent according to the adjusted ablation parameters through the composite physical field energy generation module.

[0115] The above-mentioned embodiments of the present invention provide a composite physical field adaptive ablation system based on an integrated single needle, and based on this system, provide a composite physical field adaptive ablation device based on an integrated single needle. Through the above-mentioned system and device, the parallel needle operation problem and hemostasis / implantation risk problems in ablation treatment surgery are solved.

[0116] This embodiment also discloses a computer device, such as Figure 7 As shown, the computer device includes a processor and a memory, wherein the memory stores at least one instruction, and the at least one instruction is loaded and executed by the processor to implement any of the functions of the above-mentioned integrated single-needle based composite physical field adaptive ablation system.

[0117] In addition, in the above-mentioned example implementation of the composite physical field adaptive ablation device based on an integrated single needle, the logical division of each program module is only an example. In actual applications, the above-mentioned functions can be assigned to different program modules as needed, for example, for the convenience of corresponding hardware configuration requirements or software implementation. That is, the internal structure of the composite physical field adaptive ablation device based on an integrated single needle is divided into different program modules to complete all or part of the functions described above.

[0118] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application shall be included in the scope of protection of the present application.

Claims

1. A composite physical field adaptive ablation system based on an integrated single needle, characterized in that: The system includes an integrated single needle module, a composite physical field energy generation module, an adaptive control module and an ablation parameter determination module; The integrated single needle module includes an integrated electrode needle, and the integrated electrode needle includes a plurality of different types of electrode groups, which are used to transmit different energies generated by the composite physical field energy generation module to the target ablation area to achieve precise ablation of the composite physical field, and the electrode group includes a radio frequency electrode group and a pulsed electric field electrode group; The composite physical field energy generation module is used to determine the target ablation method through the ablation treatment timing function, and the ablation treatment timing function is determined according to the type of the electrode group. The ablation treatment timing function includes a radiofrequency ablation timing function and a pulsed electric field ablation timing function. The radiofrequency ablation timing function is determined as , the pulse electric field ablation timing function is ; Determine the and When the value of When the target ablation method is determined to be radiofrequency ablation, , determining that the target ablation method is pulsed electric field ablation, determining the target energy type according to the target ablation method, generating energy according to the ablation parameters corresponding to the target energy type, and emitting the energy to the target ablation area through the integrated electrode for ablation treatment; The adaptive control module is used to monitor the target ablation area through real-time images, and adjust the ablation treatment timing function according to the monitoring results, specifically including: when sudden bleeding is monitored, the pulse electric field energy generating device is turned off and the radio frequency energy generating device is turned on by adjusting the ablation treatment timing function, the bleeding site is thermally coagulated and hemostasis is performed, and real-time image monitoring is performed during the thermal coagulation and hemostasis process until the hemostasis is successful; The ablation parameter determination module is used to determine the ablation parameters of the target ablation method through the preoperative information and intraoperative images of the target patient, and send the ablation parameters to the composite physical field energy generation module so that the composite physical field energy generation module generates energy according to the ablation parameters.

2. The system according to claim 1, characterized in that The composite physical field energy generation module includes a power supply module, a control module, a plurality of different energy driving modules, a plurality of different energy generation modules, an output switching module and an energy output interface; The power supply module includes an AC-DC conversion module and a DC-DC conversion module, which are used to perform power conversion and provide the required power for other modules; The control module is used to provide the required driving signal for the energy driving module, thereby generating the driving signal required by the energy generating module, and providing corresponding interactive information between different energy generating modules, collecting feedback signals and sending them to the adaptive control module; The output switching module and the energy output interface switch the energy and output it according to the ablation timing function.

3. The system according to claim 1, characterized in that The system also includes an image navigation function module; The image navigation function module is used to monitor the surrounding area of ​​the integrated electrode needle in real time when performing needle advancement and withdrawal operations through real-time images, adjust the needle advancement and withdrawal path according to the real-time images, and navigate according to the adjusted needle advancement and withdrawal path.

4. The system according to claim 1, characterized in that The system also includes a simulation module; The simulation module is used for performing ablation simulation according to the ablation parameters before the composite physical field energy generation module generates energy according to the ablation parameters, and determining whether the simulated ablation area generated by the ablation simulation meets expectations; When the conditions are met, informing the composite physical field energy generation module to send energy according to the ablation parameters; When it does not meet the requirements, the ablation parameters are adjusted, and ablation simulation is performed again according to the adjusted ablation parameters, until the simulated ablation area meets expectations, and energy is sent according to the adjusted ablation parameters through the composite physical field energy generation module.

Images