A polypeptide-maya blue-like pigment for make-up and a method for preparing the same

Abstract

This invention relates to the field of daily cosmetics technology, and discloses a polypeptide-Maya blue-like pigment for color cosmetics and its preparation method. First, organic pigment molecules are uniformly mixed with attapulgite clay, and then a Maya blue-like organic / inorganic hybrid pigment is prepared through high-temperature baking. Subsequently, the Maya blue-like pigment is modified with isocyanate silane using surface modification technology to obtain a silane-modified Maya blue-like pigment. Finally, polypeptides are grafted onto the surface of the Maya blue-like pigment through the coupling effect of isocyanate silane to prepare a polypeptide-Maya blue-like pigment. The polypeptide-Maya blue-like pigment prepared by this invention has safe and environmentally friendly, anti-inflammatory, anti-aging, and self-repairing effects, and good skin compatibility, making it suitable for use in color cosmetics such as lipsticks, foundation creams, eyeshadows, and blushes.

Description

Technical Field

[0001] This invention relates to the field of daily cosmetics technology, and in particular to a polypeptide-like Maya blue pigment for use in color cosmetics with anti-inflammatory, anti-aging and self-repairing effects, and its preparation method. Background Technology

[0002] Makeup pigments are substances that can alter the color of cosmetics or skin, primarily by absorbing or reflecting visible light to provide color. Based on their chemical composition, makeup pigments can be categorized into organic pigments, inorganic pigments, and metallic pigments. Organic pigments offer vibrant colors and a wide range of applications, but are easily affected by heat, light, oxygen, and chemicals, resulting in poor stability. Inorganic pigments offer good stability and a long lifespan, but their colors tend to be darker. Metallic pigments offer vibrant colors, but contain heavy metals such as lead and chromium, posing safety risks. Furthermore, long-term use of makeup can lead to dry, sensitive, and prematurely aging skin.

[0003] Peptides are compounds composed of multiple amino acids linked by peptide bonds. They possess various biological activities, including stimulating skin cells to produce collagen and elastin, thus having anti-aging effects; accelerating skin repair by promoting skin cell metabolism; preventing skin oxidation by scavenging free radicals; and whitening, moisturizing, and anti-inflammatory effects. In short, peptides can improve skin problems such as aging, damage, dryness, oxidation, inflammation, and pigmentation, keeping the skin healthy and beautiful. However, current peptide products are mainly freeze-dried powders, masks, and serums, with limited application in makeup.

[0004] To address the above problems, this invention provides a polypeptide-like Maya blue pigment with anti-inflammatory, anti-aging, and self-repairing effects for use in cosmetics, and its preparation method. Summary of the Invention

[0005] Objective of the Invention: To address the problems existing in the prior art, this invention provides a polypeptide-Maya blue-like pigment for cosmetics and its preparation method. The polypeptide-Maya blue-like pigment prepared by this invention is a safe, environmentally friendly, anti-inflammatory, and color-matchable attapulgite-based pigment. The introduction of polypeptide molecules improves the surface properties of the pigment, enhances its skin compatibility, and endows it with anti-inflammatory, self-repairing, and anti-aging properties; it is suitable for use in cosmetics such as lipsticks, foundation creams, eyeshadows, and blushes.

[0006] Technical solution: The present invention provides a method for preparing a polypeptide-Maya blue pigment for color cosmetics, comprising the following steps: S1: After mixing organic pigment molecules with purified nano-attapulgite evenly, baking them in an oven at 100-220℃ for 12-48 h, then soaking them in an ethanol solution for 6-12 h, centrifuging, drying, and grinding until no particles are present, to obtain a Maya blue organic / inorganic hybrid pigment.

[0007] S2: Take the Maya Blue organic / inorganic hybrid pigment into acetone, stir evenly, add isocyanate silane, stir at 50-85℃ for 2-3 h, centrifuge, dry, grind until no particles are present, and obtain silane-modified Maya Blue pigment.

[0008] S3: Disperse the polypeptide in ultrapure water, add silane-modified Maya blue pigment, mix evenly, stir at room temperature for 7-10 days under sealed conditions, centrifuge, dry at room temperature, and grind until no particles are present to obtain polypeptide-based Maya blue composite pigment.

[0009] Further, in S1, the mass ratio of the organic pigment molecules to the purified nano-attapulgite is 1 to 15: 100.

[0010] Furthermore, in S1, the organic pigment molecule is any one of indigo, indigo blue, methyl violet, methylene blue, Congo red, or alizarin yellow.

[0011] Furthermore, in S2, the mass ratio of the Maya Blue organic / inorganic hybrid pigment to the acetone is 1:10-20.

[0012] Further, in S2, the mass ratio of the isocyanate silane to the Maya blue-like organic / inorganic hybrid pigment is 2 to 5:100.

[0013] Furthermore, the isocyanate silane is isocyanate-propyltrimethoxysilane or isocyanate-propyltriethoxysilane.

[0014] Furthermore, in S3, the mass ratio of the polypeptide, silane-modified Mayan blue pigment, and ultrapure water is 2-10:100:500-1000.

[0015] Furthermore, the polypeptide is a commercially available cosmetic polypeptide.

[0016] Preferably, the commercially available cosmetic peptide is any one or more of collagen peptides, elastin peptides, ceramide peptides, oligopeptides, acetyl hexapeptide-8, hexapeptide, palmitoyl pentapeptide-4, carnosine, and hyaluronic acid peptides.

[0017] Preferably, in S1, the specific drying conditions are: drying temperature 60-100 ℃, drying time 6-24 h;

[0018] In S2, the specific drying conditions are: drying temperature 60-100 ℃, drying time 6-24 h.

[0019] Beneficial Effects: This invention prepares a Maya blue-like organic / inorganic hybrid pigment using high-temperature baking technology; subsequently, the Maya blue-like pigment is modified with isocyanate silane using surface modification technology to obtain a silane-modified Maya blue-like pigment; finally, peptides are grafted onto the surface of the Maya blue-like pigment through the coupling effect of isocyanate silane to prepare a peptide-Maya blue-like pigment. The peptide-Maya blue-like pigment prepared by this invention has safe and environmentally friendly, anti-inflammatory, anti-aging, and self-repairing effects, and good skin compatibility, making it suitable for use in cosmetics such as lipsticks, foundation creams, eyeshadows, and blushes.

[0020] Compared with the prior art, the present invention has the following advantages:

[0021] (1) The pigment used in this invention is a Mayan blue organic / inorganic hybrid pigment. The organic pigment molecules enter the pores (large inside and small outside) of the attapulgite-like gourd-shaped mouth through molecular thermal motion at high temperature. The free organic pigment molecules are washed away by soaking in ethanol. The attapulgite carrier is harmless to the human body, safe and healthy and has anti-inflammatory effects.

[0022] (2) The isocyanate group in the isocyanate silane used in this invention reacts with the hydroxyl group on the surface of the attapulgite to generate urethane, which is fixed on the surface of the Maya blue pigment through chemical bonds to obtain silane-modified Maya blue pigment; the isocyanate silane plays a role in sealing the attapulgite pores containing pigment molecules, preventing pigment molecules from escaping from the attapulgite pores, thereby improving the color stability of the Maya blue pigment.

[0023] (3) In this invention, the silanoxy groups on the surface of the silane-modified Maya blue pigment are further hydrolyzed to produce silanols (also called silanols), which undergo esterification with the carboxyl groups in the polypeptide at room temperature, fixing the polypeptide molecular chain on the surface of the Maya blue pigment in the form of ester groups. Therefore, through the coupling effect of isocyanate silane, the polypeptide is grafted onto the surface of the Maya blue pigment, which further improves the color stability of the pigment, and the polypeptide endows the Maya blue pigment with anti-aging, anti-oxidation, self-repairing and anti-inflammatory effects. Detailed Implementation

[0024] The present invention will now be described in detail with reference to the embodiments.

[0025] Implementation method 1:

[0026] A method for preparing a polypeptide-like Mayan blue pigment for use in cosmetics includes the following steps:

[0027] S1: Mix 10 g of commercially available organic red makeup pigment with 100 g of purified clay, bake in an oven at 180 ℃ for 36 h, soak in ethanol solution for 6 h, centrifuge, dry, and grind until no particles are present to prepare a Maya blue-red organic / inorganic hybrid pigment.

[0028] S2: Weigh 10 g of Maya blue pigment into 100 ml of acetone, stir evenly, add 1 g of isocyanate-propyltrimethoxysilane, stir at 80 ℃ in a water bath for 2 h, centrifuge, dry, and grind until no particles are present to prepare isocyanate-propyltrimethoxysilane modified Maya blue-scarlet pigment.

[0029] S3: Weigh 1 g of palmitoyl pentapeptide-4 and disperse it in 80 ml of ultrapure water. Add 10 g of the above silane-modified Maya blue pigment and mix evenly. Stir at room temperature for 7 days under sealed conditions. Centrifuge, dry at room temperature, and grind until no particles are present to prepare a polypeptide-Maya blue / scarlet composite pigment.

[0030] Implementation Method 2:

[0031] A method for preparing a polypeptide-like Mayan blue pigment for use in cosmetics includes the following steps:

[0032] S1: Mix 8 g of indigo with 100 g of purified attapulgite evenly, bake in an oven at 200 ℃ for 24 h, soak in ethanol solution for 12 h, centrifuge, dry, and grind until no particles are present to prepare a Maya blue-scarlet organic / inorganic hybrid pigment.

[0033] S2: Weigh 10 g of Maya blue pigment into 100 ml of acetone, stir evenly, add 1 g of propyltriethoxysilane isocyanate, stir at a constant temperature of 65℃ for 3 h, centrifuge, dry, and grind until no particles are present to prepare propyltriethoxysilane modified Maya blue pigment.

[0034] S3: Weigh 1 g of carnosine and disperse it in 80 ml of ultrapure water. Add 10 g of the above silane-modified Maya blue pigment and mix evenly. Stir at room temperature for 8 days under sealed conditions. Centrifuge, dry at room temperature, and grind until no particles are present to prepare a polypeptide-Maya blue / indigo composite pigment.

[0035] Implementation Method 3:

[0036] A method for preparing a polypeptide-like Mayan blue pigment for use in cosmetics includes the following steps:

[0037] S1: Mix 5 g of commercially available organic pigment light yellow with 100 g of purified attapulgite, bake in an oven at 180 ℃ for 48 h, soak in ethanol solution for 8 h, centrifuge, dry, and grind until no particles are present to prepare a Maya blue-scarlet organic / inorganic hybrid pigment.

[0038] S2: Weigh 10 g of Maya blue pigment into 100 ml of acetone, stir evenly, add 0.5 g of propyltriethoxysilane isocyanate, stir at a constant temperature of 70℃ for 3 h, centrifuge, dry, and grind until no particles are present to prepare propyltriethoxysilane modified Maya blue pigment.

[0039] S3: Weigh 0.5 g of hyaluronic acid peptide and disperse it in 90 ml of ultrapure water. Add 10 g of the above silane-modified Maya blue pigment and mix evenly. Stir at room temperature for 8 days under sealed conditions. Centrifuge, dry at room temperature, and grind until no particles are present to prepare the polypeptide-Maya blue / light yellow composite pigment.

[0040] The polypeptide-like Maya blue pigment prepared through the above-described embodiments is applied to lipstick. The specific preparation method is as follows: 15 parts of white beeswax, 5 parts of palm wax, and 5 parts of candelilla wax are heated to 60°C and melted completely. Then, the temperature is lowered to 40°C. 20 parts of shea butter, 10 parts of avocado oil, 18 parts of jojoba oil, 10 parts of coconut oil, 5 parts of olive oil, 2 parts of vitamin E, and 10 parts of polypeptide-like Maya blue pigment are mixed and dispersed at high speed for 30 minutes. The mixture is poured into a mold, cooled to room temperature, demolded, sterilized, and packaged to prepare a polypeptide-like Maya blue lipstick sample.

[0041] Its performance indicators are shown in Table 1.

[0042] Table 1 Performance Indicators of Peptide-Maya Blue Lipstick

[0043]

[0044] The effects of the Mayan blue lipstick were evaluated through a trial experiment. A comparative experiment was conducted between the lipstick prepared using the methods described above and commercially available lipsticks. 120 women aged 18-22 were selected and randomly divided into four groups based on their lip shape, color, lip lines, and degree of lip damage. The first three groups used the lipsticks prepared according to methods 1, 2, and 3 respectively, while the comparative group used commercially available lipsticks. All lipsticks were used continuously for one month. The effects of the Mayan blue lipstick were evaluated by visually observing the repair of the lips and the manifestation of various functions. The results are shown in Table 2.

[0045] Table 2 Trial Results

[0046]

[0047] As can be seen from Tables 1 and 2, the lipstick prepared using the polypeptide-type Mayan blue pigment of this invention meets the standard requirements of conventional lipsticks, does not contain heavy metals such as mercury, arsenic and lead, is safe and healthy to use, and has anti-aging and self-repairing effects.

[0048] The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand the content of the present invention and implement it accordingly. They should not be construed as limiting the scope of protection of the present invention. All equivalent transformations or modifications made in accordance with the spirit and essence of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A method for preparing a polypeptide-like Mayan blue pigment for use in color cosmetics, characterized in that, Includes the following steps: S1: Mix organic pigment molecules with purified nano-attapulgite evenly and bake in an oven at 100-220℃ for 12-48 hours. Then soak in ethanol solution for 6-12 hours, centrifuge, dry, and grind until no particles are present to obtain Maya Blue organic / inorganic hybrid pigment. S2: Take the Maya Blue organic / inorganic hybrid pigment into acetone, stir evenly, add isocyanate silane, stir at 50-85℃ for 2-3 h, centrifuge, dry, grind until no particles are present, and obtain silane-modified Maya Blue pigment. S3: Disperse the polypeptide in ultrapure water, add silane-modified Maya blue pigment, mix evenly, stir at room temperature for 7-10 days under sealed conditions, centrifuge, dry at room temperature, and grind until no particles are present to obtain polypeptide-Maya blue composite pigment.

2. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 1, characterized in that: In S1, the mass ratio of the organic pigment molecules to the purified nano-attapulgite is 1-15:

100.

3. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 1, characterized in that: In S1, the organic pigment molecule is any one of scarlet, indigo, indigo blue, methyl violet, methylene blue, Congo red, pale yellow, or alizarin yellow.

4. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 1, characterized in that: In S2, the mass ratio of the Maya Blue organic / inorganic hybrid pigment to the acetone is 1:10-20.

5. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 1, characterized in that: In S2, the mass ratio of the isocyanate silane to the Maya blue-like organic / inorganic hybrid pigment is 2 to 5:

100.

6. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 5, characterized in that: The isocyanate silane is isocyanate-propyltrimethoxysilane or isocyanate-propyltriethoxysilane.

7. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 1, characterized in that: In S3, the mass ratio of the polypeptide, silane-modified Mayan blue pigment, and ultrapure water is 2-10:100:500-1000.

8. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 7, characterized in that: The polypeptide is a commercially available cosmetic polypeptide.

9. The method for preparing the polypeptide-Mayan blue pigment for color cosmetics according to claim 8, characterized in that: The commercially available cosmetic peptides are any one or more of collagen peptides, elastin peptides, ceramide peptides, oligopeptides, acetyl hexapeptide-8, hexapeptide, palmitoyl pentapeptide-4, carnosine, and hyaluronic acid peptides.

10. A method for preparing a polypeptide-Mayan blue pigment for color cosmetics according to any one of claims 1-9, characterized in that: In S1, the specific drying conditions are: drying temperature 60-100 ℃, drying time 6-24 h; In S2, the specific drying conditions are: drying temperature 60-100 ℃, drying time 6-24 h.

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