Current control circuit and focused transcranial electrical stimulation device

Abstract

The present invention provides a current control circuit, which is applied to a focused transcranial electrical stimulation device, comprising: a control unit, which is used to generate a polarity wave and multiple amplitude setting signals according to an external current setting signal; a fundamental wave processing unit, which comprises a multi-channel amplitude setting circuit, which is connected to the control unit and is used to perform amplitude modulation processing on the polarity wave according to multiple amplitude setting signals respectively, so as to obtain multiple independent polarity amplitude modulation waves; a constant current output unit, which comprises multiple operational amplifier constant current output circuits respectively connected to multiple electrodes of the focused transcranial electrical stimulation device, and the multiple operational amplifier constant current output circuits are also connected to the external power supply and the multi-channel amplitude setting circuit, and are used to control the current output to the corresponding electrodes according to the voltage amplitudes of multiple polarity amplitude modulation waves and the corresponding current setting resistors in the operational amplifier constant current output circuits. A focused transcranial electrical stimulation device is also disclosed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a current control circuit and a focused transcranial electrical stimulation device. Background Art

[0002] Transcranial electrical stimulation (tES) is a safe, tolerable, non-invasive brain stimulation technology that uses two or more electrodes placed on the scalp to pass a weak current through the cerebral cortex, changing the excitation state of neurons and thus changing the function of certain brain regions. tES includes a variety of stimulation modes: transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), random noise stimulation (tRNS) and transcranial pulsed electrical stimulation (tPCS), etc. The commonly used current is ≤2mA, and it has a good therapeutic effect on a variety of mental or brain injury diseases such as aphasia, dysphagia, spasticity, impaired consciousness, cognitive impairment, and depression.

[0003] Because traditional transcranial electrical stimulation devices use a yin-yang stimulation method, the current diffuses widely in the area between the yin and yang electrodes, the treatment point is inaccurate, and the stimulation effect is weakened; in order to improve the stimulation effect, a focused stimulation method is currently used in which four auxiliary electrodes are arranged around the central electrode to greatly reduce the current radiation area, so that the point is accurate and the current is concentrated, and the treatment effect has been greatly improved. However, most of the transcranial electrical stimulation devices on the market that use the focused stimulation method simply divide one output into four, and the four auxiliary electrodes are output in parallel. The four currents affect each other, and the total current of the central electrode is determined, but the current of the four auxiliary electrodes cannot be controlled. Summary of the invention

[0004] The present invention provides a current control circuit and a focused transcranial electrical stimulation device, aiming to solve the problem that the current of the electrode cannot be adjusted in the current of the current-controlled transcranial electrical stimulation device.

[0005] According to one aspect of the present invention, there is provided a current control circuit for use in a focused transcranial electrical stimulation device, the current control circuit comprising:

[0006] A control unit, used for generating a polarity wave and a plurality of amplitude setting signals according to an external current setting signal;

[0007] A fundamental wave processing unit, comprising a multi-channel amplitude setting circuit, the multi-channel amplitude setting circuit is connected to the control unit, and is used to perform amplitude modulation processing on the polar wave according to a plurality of amplitude setting signals, so as to obtain a plurality of independent polarity amplitude modulated waves;

[0008] The constant current output unit includes a plurality of operational amplifier constant current output circuits respectively connected to the plurality of electrodes of the focused transcranial electrical stimulation device, and the plurality of operational amplifier constant current output circuits are also connected to the external power supply and the multi-channel amplitude setting circuit, and are used to control the current output to the corresponding electrodes according to the voltage amplitudes of the plurality of polarity amplitude modulation waves and the corresponding current setting resistors in the operational amplifier constant current output circuits.

[0009] Its further technical solution is: the fundamental wave processing unit also includes a fundamental wave polling sampling circuit, which is connected to the output end of the multi-channel amplitude setting circuit and the control unit, and is used to collect the polarity amplitude modulation wave of the positive half cycle of each polarity amplitude modulation wave and feed it back to the control unit, so that the control unit adjusts the output of the corresponding channel in the multi-channel amplitude setting circuit according to the voltage amplitude of the polarity amplitude modulation wave of the positive half cycle fed back.

[0010] A further technical solution is as follows: the fundamental wave polling sampling circuit comprises a first single-pole multi-throw analog switch, a first comparator and a first single-pole double-throw analog switch, wherein:

[0011] The multiple input ends of the first single-pole multi-throw analog switch are respectively connected to the multiple output ends of the multi-channel amplitude setting circuit, so as to realize the turn-on sampling of multiple polarity amplitude modulation waves;

[0012] The input end of the first comparator is connected to the output end of the first single-pole multi-throw analog switch, and is used to determine whether the polarity amplitude modulation wave is in a positive half cycle;

[0013] The first single-pole double-throw analog switch is connected between the output end of the first comparator and the control unit, and is used for being turned on when the polarity amplitude modulation wave is in the positive half cycle to feed back the polarity amplitude modulation wave of the positive half cycle to the control unit.

[0014] Its further technical solution is: the current control circuit also includes a sampling monitoring unit, which is connected to the output ends of the multiple operational amplifier constant current output circuits and the control unit, and is used to collect the output voltage output to the corresponding electrode in each operational amplifier constant current output circuit, and feed it back to the control unit, so that the control unit can obtain the load impedance connected to the corresponding operational amplifier constant current output circuit according to the multiple output voltages and the output currents output to the electrodes by the multiple operational amplifier constant current output circuits, thereby realizing connection monitoring.

[0015] A further technical solution is as follows: the sampling monitoring unit includes an output polling sampling circuit, the output polling sampling circuit includes a plurality of isolation operational amplifiers, a second single-pole multi-throw analog switch, a second comparator and a second single-pole double-throw analog switch, wherein:

[0016] Each of the operational amplifier constant current output circuits is connected to the non-inverting input terminal of an isolation operational amplifier through a resistor voltage divider circuit, and the inverting input terminal of the isolation operational amplifier is connected to its output terminal;

[0017] The multiple input ends of the second single-pole multi-throw analog switch are respectively connected to the output ends of the multiple isolation operational amplifiers, so as to realize the turn-on sampling of the multiple output voltage signals;

[0018] The input end of the second comparator is connected to the output end of the second single-pole multi-throw analog switch, and is used to determine whether the output voltage is greater than 0;

[0019] The second single-pole double-throw analog switch is connected between the output end of the second comparator and the control unit, and is configured to be turned on when the output voltage is greater than 0 so as to feed the output voltage back to the control unit.

[0020] A further technical solution is: the output polling sampling circuit also includes a third single-pole double-throw analog switch and an output operational amplifier, wherein:

[0021] The input end of the third single-pole double-throw analog switch is connected to the output end of the second comparator, and the output end of the third single-pole double-throw analog switch is connected to the output operational amplifier, and is used to be turned on when the output voltage is less than a preset voltage threshold;

[0022] The non-inverting input terminal of the output operational amplifier is connected to the output terminal of the third single-pole double-throw analog switch, the inverting input terminal thereof is connected to the 60th resistor and one end of the 57th resistor, the output terminal thereof is connected to the other end of the 57th resistor and the control unit, and the other end of the 60th resistor is grounded.

[0023] Its further technical solution is: when the polarity wave generated by the control unit is a unipolar wave, the fundamental wave processing unit also includes a polarity conversion circuit, the polarity conversion circuit is connected to the control unit and the multi-channel amplitude setting circuit, and is used to convert the unipolar wave into a bipolar wave, and the multi-channel amplitude setting circuit is used to perform amplitude modulation processing on multiple bipolar waves according to multiple amplitude setting signals respectively, so as to obtain multiple independent bipolar amplitude modulated waves.

[0024] Its further technical solution is: the multi-channel amplitude setting circuit includes a multi-channel digital potentiometer and multiple voltage followers, the input end of the multi-channel digital potentiometer is connected to the control unit, used to receive multiple amplitude setting signals and polarity waves from the control unit, and respectively perform amplitude modulation processing on the polarity wave according to the multiple amplitude setting signals to obtain multiple polarity amplitude modulated waves; the input ends of the multiple voltage followers are respectively connected to the multiple output ends of the multi-channel digital potentiometer to obtain multiple independent polarity amplitude modulated waves.

[0025] According to another aspect of the present invention, there is provided a focused transcranial electrical stimulation device, which includes an electrode cap and the above-mentioned current control circuit, wherein a plurality of electrodes are distributed on the electrode cap, and a plurality of operational amplifier constant current output circuits of the current control circuit are respectively connected to the plurality of electrodes.

[0026] A further technical solution is: the focused transcranial electrical stimulation device also includes a human-computer interaction unit, the human-computer interaction unit includes a display module and a keyboard module, and the display module and the keyboard module are both connected to the control unit.

[0027] Compared with the prior art, the control unit in the current control circuit of the present invention can generate a polarity wave and multiple amplitude setting signals according to an external current setting signal, the multi-channel amplitude setting circuit in the fundamental wave processing unit can respectively perform amplitude modulation processing on the multiple polarity waves according to the multiple amplitude setting signals to obtain multiple independent polarity amplitude modulation waves, the operational amplifier constant current output circuit in the constant current output unit can be connected to the electrodes in the external device to provide current, and the operational amplifier constant current output circuit can adjust the current output to the corresponding electrode according to the voltage amplitude of the polarity amplitude modulation wave and the current setting resistance control in its circuit. When the current control circuit of the present invention is applied to an external device, such as a focused transcranial electrical stimulation device, the size of the current output to each electrode can be arbitrarily set within the maximum output current allowable range, and the multiple output currents are independent, do not affect each other, and are adjustable, so that the device can support richer and more delicate treatment plans, ensure a more stable and sufficient stimulation effect, and make the treatment more intuitive and controllable. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying any creative work.

[0029] Figure 1 is a schematic diagram of a structural block diagram of a current control circuit provided by an embodiment of the present invention;

[0030] Figure 2 yes Figure 1 A circuit diagram of a control unit and a multi-channel amplitude setting circuit in the current control circuit shown;

[0031] Figure 3 yes Figure 1 A circuit diagram of a fundamental wave polling sampling circuit in the current control circuit shown;

[0032] Figure 4 yes Figure 1A circuit diagram of an operational amplifier constant current output circuit in the current control circuit shown;

[0033] Figure 5 yes Figure 1 A circuit diagram of an isolated operational amplifier in the current control circuit shown;

[0034] Figure 6 yes Figure 1 The circuit diagram of the output polling sampling circuit in the current control circuit shown. DETAILED DESCRIPTION

[0035] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0036] It should be understood that when used in this specification and the appended claims, the terms "include" and "comprises" indicate the presence of described features, integers, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integers, operations, elements, components and / or groups thereof.

[0037] It should also be understood that the terms used in this specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. As used in the specification of the present invention and the appended claims, unless the context clearly indicates otherwise, the singular forms of "a", "an" and "the" are intended to include plural forms. It should also be further understood that the term "and / or" used in the specification of the present invention and the appended claims refers to any combination of one or more of the associated listed items and all possible combinations, and includes these combinations.

[0038] Reference Figures 1 to 6 , Figures 1 to 6A specific embodiment of the current control circuit of the present invention is shown. The current control circuit can be applied to a focused transcranial electrical stimulation device and the like, and is used to control and adjust the current input to the device according to actual needs. In the embodiment shown in the accompanying drawings, the current control circuit includes a control unit 10, a fundamental wave processing unit 20, and a constant current output unit 30, wherein the control unit 10 is used to generate a polarity wave and multiple amplitude setting signals according to an external current setting signal; the fundamental wave processing unit 20 includes a multi-channel amplitude setting circuit 21, and the multi-channel amplitude setting circuit 21 is connected to the control unit 10, and is used to perform amplitude modulation processing on the polarity wave according to multiple amplitude setting signals, respectively, to obtain multiple independent polarity amplitude modulation waves; the constant current output unit 30 includes multiple operational amplifier constant current output circuits 31 respectively connected to multiple electrodes 200 of the focused transcranial electrical stimulation device, and the multiple operational amplifier constant current output circuits 31 are also connected to the external power supply and the multi-channel amplitude setting circuit 21, and are used to control the current output to the corresponding electrode 200 according to the voltage amplitude of multiple polarity amplitude modulation waves and the corresponding current setting resistor in the operational amplifier constant current output circuit 31. Preferably, the control unit 10 can be implemented by a microprocessor; in this embodiment, the number of electrodes 200 to be powered is four, then the amplitude setting signal is four, and the multi-channel amplitude setting circuit 21 can correspondingly be a four-channel amplitude setting circuit, and the operational amplifier constant current output circuit 31 can correspondingly be set to four. It can be understood that in some other embodiments, the number of the above circuits can also be adjusted according to the number of electrodes 200 to be powered.

[0039] In this embodiment, the polarity wave generated by the control unit 10 is a unipolar wave, and the fundamental wave processing unit 20 may also include a polarity conversion circuit 23, which is connected to the control unit 10 and the multi-channel amplitude setting circuit 21, and is used to convert the unipolar wave into a bipolar wave. The multi-channel amplitude setting circuit 21 is used to perform amplitude modulation processing on the bipolar wave according to multiple amplitude setting signals respectively to obtain multiple independent bipolar amplitude modulated waves. The DAC in the microprocessor can generate a unipolar wave, and the waveform can be in any style. The polarity conversion circuit 23 may include an operational amplifier, and the conversion of the unipolar wave and the bipolar wave is realized by the operational amplifier.

[0040] Continue to refer to Figure 2In the embodiment shown in the accompanying drawings, the multi-channel amplitude setting circuit 21 includes a four-channel digital potentiometer U1 and four voltage followers (U2A, U2B, U2C, U2D). The model of the four-channel digital potentiometer U1 can be AD5263BRUZ20, and its input end is connected to the control unit 10, for receiving four amplitude setting signals and polarity waves from the control unit 10, and performing amplitude modulation processing on the polarity waves according to the four amplitude setting signals respectively, so as to obtain four polarity amplitude modulation waves with the same or different voltage amplitudes; the input ends of the four voltage followers (U2A, U2B, U2C, U2D) are respectively connected to the multiple output ends of the four-channel digital potentiometer U1, so as to obtain four independent polarity amplitude modulation waves.

[0041] Furthermore, in some embodiments, the fundamental wave processing unit 20 also includes a fundamental wave polling sampling circuit 22, and the fundamental wave polling sampling circuit 22 is connected to the output end of the multi-channel amplitude setting circuit 21 and the control unit 10, and is used to collect the polarity amplitude modulation wave of the positive half cycle of each polarity amplitude modulation wave and feed it back to the control unit 10, so that the control unit 10 adjusts the output of the corresponding channel in the multi-channel amplitude setting circuit 21 according to the voltage amplitude of the fed back positive half cycle polarity amplitude modulation wave, so that the voltage amplitude of each output polarity amplitude modulation wave is more accurate.

[0042] Specifically, Figure 3 As shown, in the embodiment shown in the accompanying drawings, the fundamental wave polling sampling circuit 22 includes a first single-pole four-throw analog switch U3, a first comparator U4 and a first single-pole double-throw analog switch U5, wherein the multiple input ends of the first single-pole four-throw analog switch U3 are respectively connected to the four output ends of the multi-channel amplitude setting circuit 21, so as to realize the sampling of four polarity amplitude modulated waves in turn; the input end of the first comparator U4 is connected to the output end of the first single-pole four-throw analog switch U3, so as to determine whether the polarity amplitude modulated wave is in the positive half cycle; the first single-pole double-throw analog switch U5 is connected between the output end of the first comparator U4 and the control unit 10, so as to be turned on when the polarity amplitude modulated wave is in the positive half cycle to feed back the polarity amplitude modulated wave of the positive half cycle to the control unit 10. Based on the above design, the first comparator U4 compares the bipolar amplitude modulated wave with 0V, and controls the first single-pole double-throw analog switch U5 according to the comparison result, that is, when the bipolar amplitude modulated wave is in the negative half cycle, the first single-pole double-throw analog switch U5 is disconnected, and the microprocessor sampling value is 0; when the bipolar amplitude modulated wave is in the positive half cycle, the first single-pole double-throw analog switch U5 transmits the bipolar amplitude modulated wave of the positive half cycle to the microprocessor for sampling, thereby achieving the purpose of eliminating the negative half cycle of the bipolar amplitude modulated wave.

[0043] Preferably, if Figure 4 As shown, Figure 4The specific circuit structure diagram of one of the operational amplifier constant current output circuits 31 is shown in the figure. In the embodiment shown in the figure, the operational amplifier constant current output circuit 31 is a dual operational amplifier constant current output circuit, including a first operational amplifier U22 and a second operational amplifier U21, and the current setting resistor Rseti1 is connected between the output end of the first operational amplifier U22 and the in-phase input end of the second operational amplifier U21. In this embodiment, the resistance value of the current setting resistor Rseti1 is 1kΩ, and the output current is set to the ratio of the voltage amplitude of the polarity amplitude modulation wave to the current setting resistor Rseti1 of 1kΩ, that is, the output current can be adjusted by adjusting the amplitude of the polarity amplitude modulation wave, and the output current value is not affected by the size of the load impedance connected to the operational amplifier constant current output circuit 31.

[0044] In some embodiments, the current control circuit also includes a sampling monitoring unit 40, which is connected to the output end of the four operational amplifier constant current output circuits 31 and the control unit 10, and is used to collect the output voltage output to the corresponding electrode 200 in each operational amplifier constant current output circuit 31, and feed it back to the control unit 10, so that the control unit 10 obtains the load impedance connected to the corresponding operational amplifier constant current output circuit 31 according to the four output voltages and the output current output to the electrode 200 by the four operational amplifier constant current output circuits 31, thereby realizing connection monitoring. Understandably, the output voltage value is the product of the output current and the load impedance, and the load impedance size can be known by the collected output voltage and the output current of the operational amplifier constant current output circuit 31. Based on the above design, the current control circuit can monitor the load impedance of each channel in real time through the sampling monitoring unit 40 during the entire output process, and realize real-time monitoring of the connection quality of each channel. For example, if the load impedance is infinite, it means that the channel connection is disconnected.

[0045] Specifically, Figure 5 and Figure 6As shown, the sampling monitoring unit 40 includes an output polling sampling circuit 41, and the output polling sampling circuit 41 includes four isolated operational amplifiers (U32A, U32B, U32C, U32D), a second single-pole four-throw analog switch U23, a second comparator U10 and a second single-pole double-throw analog switch U33, wherein each of the operational amplifier constant current output circuits 31 is connected to the non-inverting input terminal of the isolated operational amplifier through a resistor voltage divider circuit 311, and the inverting input terminal of the isolated operational amplifier is connected to its output terminal; in this embodiment, the resistor voltage divider circuit 311 is used for voltage division, and a voltage follower is formed with the isolated operational amplifier (U32A, U32B, U32C, U32D) to isolate the previous stage circuit, and -30V~+3 The output voltage amplitude of 0V is reduced by 10 times to -3V~+3V to meet the ADC sampling voltage range of the control unit 10; the four input ends of the second single-pole four-throw analog switch U23 are respectively connected to the output ends of the four isolated operational amplifiers (U32A, U32B, U32C, U32D) to realize the alternating conduction sampling of the four output voltage signals; the input end of the second comparator U10 is connected to the output end of the second single-pole four-throw analog switch U23 to determine whether the output voltage is greater than 0; the second single-pole double-throw analog switch U33 is connected between the output end of the second comparator U10 and the control unit 10, and is used to be turned on when the output voltage is greater than 0 to feed the output voltage back to the control unit 10.

[0046] Furthermore, in order to avoid inaccurate sampling values ​​or failure to sample the control unit 10 due to a voltage amplitude that is too small, the output polling sampling circuit 41 also includes a third single-pole double-throw analog switch U6 and an output operational amplifier U25A, wherein the third single-pole double-throw analog switch U6 is connected to the second comparator U10 and the second single-pole four-throw analog switch U23, and the output end of the third single-pole double-throw analog switch U6 is connected to the output operational amplifier U25A, which is used to be turned on when the output voltage is less than a preset voltage threshold; the non-inverting input end of the output operational amplifier U25A is connected to the output end of the third single-pole double-throw analog switch U6, and the inverting input end thereof is connected to the sixtieth resistor R60 and one end of the fifty-seventh resistor R57, and the output end thereof is connected to the other end of the fifty-seventh resistor R57 and the control unit 10, and the other end of the sixtieth resistor R60 is grounded. In this embodiment, when the output voltage is less than 0.3V, the third single-pole double-throw analog switch U6 is turned on to amplify the output voltage through the output operational amplifier U25A, for example, by 10 times, and then provide it to the control unit 10 for sampling after returning to its original size.

[0047] The present invention can also provide a focused transcranial electrical stimulation device, comprising an electrode cap and the current control circuit described in the above embodiment, wherein four electrodes 200 and one common electrode are distributed on the electrode cap, and the four electrodes 200 are placed around the common electrode as the center, and the four operational amplifier constant current output circuits 31 of the current control circuit are respectively connected to the four electrodes 200, and the common electrode is connected to the common ground reference terminal GND of the device. Then, the current peak value of the common electrode is the sum of the output currents of the four operational amplifier constant current output circuits 31, and the current direction is opposite to the output current direction of the operational amplifier constant current output circuit 31.

[0048] Furthermore, the focused transcranial electrical stimulation device may also include a human-machine interaction unit, which includes a display module and a keyboard module, and both the display module and the keyboard module are connected to the control unit 10. The display module may be an LCD display screen, which may be connected to the control unit 10 via an FPC cable to display the device operating status and output parameters in real time, such as displaying the treatment mode, the output current of each channel, the load impedance of each channel, etc.; the keyboard module includes up, down, left, right and confirmation keys, which are also connected to the control unit 10, and different treatment modes can be selected and different treatment parameters can be set as needed.

[0049] It can be understood that when the focused transcranial electrical stimulation device of this embodiment is used, the power is turned on, and the medical staff or the user can select the treatment parameters by themselves through the buttons in the keyboard module, select the set current size, generate an external current setting signal, and the current control circuit works. The microprocessor generates a unipolar wave and four amplitude setting signals according to the external current setting signal, and the polarity conversion circuit 23 converts the unipolar wave into a bipolar wave. After passing through the multi-channel amplitude setting circuit 21, one bipolar wave is divided into four bipolar amplitude modulated waves, and the period remains unchanged. The amplitudes of the four bipolar amplitude modulated waves are set respectively according to the four amplitude setting signals. The four bipolar amplitude modulated waves will be successively removed by the fundamental wave polling sampling circuit 22 after the negative half cycle is removed and then transmitted to the ADC of the microprocessor for sampling. The microprocessor samples the multiple channels in the multi-channel amplitude setting circuit 21 according to the sampled values. The amplitude of the four-way bipolar amplitude modulated wave output by the channel digital potentiometer U1 is fine-tuned to make the amplitude of the four-way bipolar amplitude modulated wave output more accurate. At the same time, the four-way bipolar amplitude modulated wave is also transmitted to the four operational amplifier constant current output circuits 31 respectively. The output current value is the ratio of the amplitude of the bipolar amplitude modulated wave to the current setting resistor Rseti1 of 1kΩ, which is transmitted to the four electrodes 200 of the electrode cap respectively for stimulation treatment. In addition, the output voltage of the four operational amplifier constant current output circuits 31 can be sampled by the output polling sampling circuit 41, and the load impedance of each channel connection can be obtained by combining its output current, so as to monitor the connection quality of each electrode 200 in real time, to avoid the situation where one or several channel electrodes 200 have fallen off but it is unknown, thereby causing ineffective treatment, and reminders can be displayed on the LCD screen.

[0050] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can easily think of various equivalent modifications or replacements within the technical scope disclosed by the present invention, and these modifications or replacements should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention shall be based on the protection scope of the claims.

Claims

1. A current control circuit, applied to a focused transcranial electrical stimulation device, characterized in that: The current control circuit comprises: A control unit, used for generating a polarity wave and a plurality of amplitude setting signals according to an external current setting signal; A fundamental wave processing unit, comprising a multi-channel amplitude setting circuit and a fundamental wave polling sampling circuit, wherein the multi-channel amplitude setting circuit is connected to the control unit and is used to perform amplitude modulation processing on the polar wave according to multiple amplitude setting signals respectively, so as to obtain multiple independent polarity amplitude modulated waves; the fundamental wave polling sampling circuit comprises a first single-pole multi-throw analog switch, a first comparator and a first single-pole double-throw analog switch, wherein multiple input ends of the first single-pole multi-throw analog switch are respectively connected to multiple output ends of the multi-channel amplitude setting circuit, so as to realize the turn-on sampling of multiple polarity amplitude modulated waves; the input end of the first comparator is connected to the output end of the first single-pole multi-throw analog switch, so as to determine whether the polarity amplitude modulated wave is in a positive half cycle; the first single-pole double-throw analog switch is connected between the output end of the first comparator and the control unit, so as to be turned on when the polarity amplitude modulated wave is in a positive half cycle to feed back the polarity amplitude modulated wave of the positive half cycle to the control unit, so that the control unit adjusts the output of the corresponding channel in the multi-channel amplitude setting circuit according to the voltage amplitude of the polarity amplitude modulated wave of the positive half cycle fed back; The constant current output unit includes a plurality of operational amplifier constant current output circuits respectively connected to the plurality of electrodes of the focused transcranial electrical stimulation device, wherein the plurality of operational amplifier constant current output circuits are also connected to an external power supply and the multi-channel amplitude setting circuit, and are used to control the current output to the corresponding electrodes according to the voltage amplitudes of the plurality of polarity amplitude modulation waves and the corresponding current setting resistors in the operational amplifier constant current output circuits.

2. The current control circuit according to claim 1, characterized in that: The current control circuit also includes a sampling monitoring unit, which is connected to the output ends of the multiple operational amplifier constant current output circuits and the control unit, and is used to collect the output voltage output to the corresponding electrode in each operational amplifier constant current output circuit, and feed it back to the control unit, so that the control unit can obtain the load impedance connected to the corresponding operational amplifier constant current output circuit according to the multiple output voltages and the output currents output to the electrodes by the multiple operational amplifier constant current output circuits, thereby realizing connection monitoring.

3. The current control circuit according to claim 2, characterized in that: The sampling monitoring unit includes an output polling sampling circuit, which includes a plurality of isolation operational amplifiers, a second single-pole multi-throw analog switch, a second comparator, and a second single-pole double-throw analog switch, wherein: Each of the operational amplifier constant current output circuits is connected to the non-inverting input terminal of an isolation operational amplifier through a resistor voltage divider circuit, and the inverting input terminal of the isolation operational amplifier is connected to its output terminal; The multiple input ends of the second single-pole multi-throw analog switch are respectively connected to the output ends of the multiple isolation operational amplifiers, so as to realize the turn-on sampling of the multiple output voltage signals; The input end of the second comparator is connected to the output end of the second single-pole multi-throw analog switch, and is used to determine whether the output voltage is greater than 0; The second single-pole double-throw analog switch is connected between the output end of the second comparator and the control unit, and is configured to be turned on when the output voltage is greater than 0 so as to feed the output voltage back to the control unit.

4. The current control circuit according to claim 3, characterized in that: The output polling sampling circuit also includes a third single-pole double-throw analog switch and an output operational amplifier, wherein: The input end of the third single-pole double-throw analog switch is connected to the output end of the second comparator, and the output end of the third single-pole double-throw analog switch is connected to the output operational amplifier, and is used to be turned on when the output voltage is less than a preset voltage threshold; The non-inverting input terminal of the output operational amplifier is connected to the output terminal of the third single-pole double-throw analog switch, the inverting input terminal thereof is connected to the 60th resistor and one end of the 57th resistor, the output terminal thereof is connected to the other end of the 57th resistor and the control unit, and the other end of the 60th resistor is grounded.

5. The current control circuit according to claim 1, characterized in that: When the polarity wave generated by the control unit is a unipolar wave, the fundamental wave processing unit also includes a polarity conversion circuit, which is connected to the control unit and the multi-channel amplitude setting circuit and is used to convert the unipolar wave into a bipolar wave. The multi-channel amplitude setting circuit is used to perform amplitude modulation processing on the multiple bipolar waves according to multiple amplitude setting signals respectively to obtain multiple independent bipolar amplitude modulated waves.

6. The current control circuit according to claim 1, characterized in that: The multi-channel amplitude setting circuit includes a multi-channel digital potentiometer and multiple voltage followers. The input end of the multi-channel digital potentiometer is connected to the control unit for receiving multiple amplitude setting signals and polarity waves from the control unit, and performing amplitude modulation processing on the polarity waves according to the multiple amplitude setting signals respectively to obtain multiple polarity amplitude modulated waves; the input ends of the multiple voltage followers are respectively connected to the multiple output ends of the multi-channel digital potentiometer for obtaining multiple independent polarity amplitude modulated waves.

7. A focused transcranial electrical stimulation device, characterized in that: It comprises an electrode cap and the current control circuit according to any one of claims 1 to 6, wherein a plurality of electrodes are distributed on the electrode cap, and a plurality of operational amplifier constant current output circuits of the current control circuit are respectively connected to the plurality of electrodes.

8. The focused transcranial electrical stimulation device according to claim 7, characterized in that: The focused transcranial electrical stimulation device further comprises a human-computer interaction unit, which comprises a display module and a keyboard module, and both the display module and the keyboard module are connected to the control unit.

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