Voxelized human body model and neutron dose assessment method
Through voxelized human body models and neutron dose evaluation methods, the problem that human body models in the prior art fail to effectively consider the differences in the internal structure of the human body is solved, and the efficiency and accuracy of neutron dose evaluation is improved, reducing experimental costs and improving flexibility.
Patent Information
- Application Number
- CN202410897412.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-05
- Publication Date
- 2025-04-11
- Estimated Expiration
- 2044-07-05
AI Technical Summary
The human body model in the prior art fails to effectively consider the differences in elemental composition and density of the internal bones, muscles and various organs of the human body in neutron dose evaluation, and the model is costly and has a single use scenario, which is not conducive to promotion.
The voxelized human body model is used to detect the human body parameters of the irradiated person, and the various organs of the human body are simulated by stacking model unit blocks, and the human body model is formed according to the relative positions of the organs in the real human body. The model unit block includes a cube container and a sodium solution filled therein, and neutron irradiation and induction 24Na activity detection is performed.
The efficiency of neutron dose evaluation is improved, and the spatial distribution of sodium in the human body can be more accurately simulated, the dose evaluation of each organ is simplified, the cost of experiment is reduced, and the flexibility and scalability of experiments are improved.
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Figure CN118778092B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of nuclear radiation protection, and relates to a voxelized human body model and a neutron dose assessment method. Background Art
[0002] In nuclear explosions and nuclear accidents, neutron external exposure is an important source of human radiation. Therefore, when people are exposed to nuclear radiation, timely and accurate assessment of neutron external exposure dose is of great value for medical treatment of the injured and assessment of the degree of harm of the accident.
[0003] The dose assessment method for measuring the induced radioactivity generated by neutron irradiation in the human body is called neutron activation method, which is a neutron-specific external dose assessment method. Specifically, when a person is irradiated by neutron rays, the neutrons will react with the body's internal organs. 23 The Na element undergoes a radiation capture reaction to produce radionuclides 24 Na, 24 Na is a radioactive nuclide that will produce β - decay:
[0004]
[0005] 24 The half-life of Na is 14.997h. Among the characteristic gamma rays produced by decay, the two strongest characteristic gamma rays have energies of 1369keV and 2754keV. 24 The intensity of gamma rays produced by Na decay can be used to calculate the neutron dose to the human body. Sodium accounts for 0.15% of the total weight of the human body and is one of the constant elements in the human body. 24 Na has a moderate half-life and high characteristic gamma-ray intensity. The neutron activation method has the advantages of easy sample acquisition, short measurement time, and rapid dose assessment at the accident site.
[0006] However, the current research on neutron dose assessment is mostly based on simulation calculations. Through real CT images, a digital human model is constructed. The Monte Carlo method is used to simulate the digital human model of neutron irradiation to evaluate the neutron dose and human induced 24 Na activity. In neutron irradiation experiments, a human body model made of equivalent human tissue materials with element content similar to that of the human body is usually used to replace the real human body; however, the human body model in the prior art is a cubic water tank filled with an aqueous solution containing the sodium element, which has the disadvantage of not considering the differences in element composition and density of bones, muscles, and various organs inside the human body: In addition, the prior art also discloses an accurate human body model with reference to standard data, which has the following disadvantages: the tissues and organs in the above human body model are often solid, and the induced effects on the whole body and different tissues and organs after irradiation are different. 24The measurement of Na activity is very difficult, and this model is expensive to produce and has a single usage scenario, which is not conducive to popularization and use.
[0007] Therefore, a voxelized human body model with high measurement efficiency and a neutron dose assessment method are urgently needed. Summary of the invention
[0008] The present invention provides a voxelized human body model and a neutron dose assessment method to solve at least one problem existing in the prior art.
[0009] To achieve the above object, the present invention provides a neutron dose assessment method based on a voxelized human body model, the method comprising:
[0010] Detection of human parameters and neutron-induced 24 Na activity;
[0011] Based on the human body parameters of the irradiated person, various organs of the human body are simulated by stacking model unit blocks; the simulated organs are combined to form a human body model according to the relative positions of the organs in the real human body; wherein the model unit block includes a cubic container and a sodium solution filled in the cubic container;
[0012] irradiating the human body model with a unit dose of neutrons according to the neutron energy distribution and irradiation geometric conditions of the neutron irradiated personnel;
[0013] Using radiation detectors to detect neutron induction in a human body model after neutron irradiation 24 Na activity was tested;
[0014] Based on the human body model neutron induction 24 Na activity, the neutron dose to the irradiated personnel is determined according to the following formula;
[0015] D1=(A1 / A0)·D0
[0016] Among them, D1 is the neutron dose of the exposed personnel; A1 is the neutron-induced 24 Na activity; A0 is the neutron-induced 24 Na activity; D0 is the unit dose of neutron irradiation.
[0017] Further, preferably, when the organ to be simulated by the model unit block is the lung or the oral and nasal cavity, the cubic container includes a hollow cube, in which a partition wall is arranged to divide the inner cavity of the cube into a central chamber and a peripheral chamber, the central chamber is filled with air, and the peripheral chamber is filled with a sodium solution.
[0018] Further, preferably, the cubic container is a cube with outer dimensions of 5cm×5cm×5cm and a wall thickness of 1mm; the partition wall is 1mm thick; and the central cavity is a space of 4.26cm×4.26cm×4.8cm.
[0019] Furthermore, preferably, the cubic container is made of polytetrafluoroethylene, plexiglass or polyethylene.
[0020] Further, preferably, the sodium solution is one of sodium carbonate solution, sodium acetate solution, sodium lactate or sodium citrate.
[0021] Further, preferably, the sodium solution comprises a first concentration sodium solution, a second concentration sodium solution and a third concentration sodium solution with a sodium content ratio of 1:2:4; the first concentration sodium solution is used to fill the model unit blocks constituting the brain, heart, lungs, oral and nasal cavity, stomach, small intestine, colon, gallbladder, pancreas, spleen, thymus, thyroid, muscle, fat and bone;
[0022] The second concentration sodium solution is used to fill the model unit blocks that make up the liver and kidneys;
[0023] The third concentration sodium solution is used to fill the model unit blocks that constitute the bladder.
[0024] The present invention also includes a voxelized human body model, which is composed of simulated organs combined according to the relative positions of organs in a real human body; the simulated organs are composed of model unit blocks stacked according to the human body parameters of the person to be irradiated; wherein the model unit blocks include a cubic container and an equivalent tissue solution filled in the cubic container; the voxelized human body model is applied to the neutron dose assessment method based on the voxelized human body model as described above.
[0025] Further, preferably, when the voxelized human body model is applied to neutron irradiation human body induction 24 When the Na activity is detected, the equivalent tissue fluid is a sodium solution;
[0026] When the voxelized human body model is applied to neutron-induced 42 During the Ca radioactivity test, the equivalent tissue fluid in the model unit blocks constituting the bones is 10% calcium nitrate solution, and the equivalent tissue fluid in the model unit blocks constituting organs other than bones is water;
[0027] When the voxelized human body model is applied to the gamma ray irradiation dose detection of the human body, the element ratio of the equivalent tissue fluid is hydrogen: nitrogen: oxygen: carbon = 10.5: 2.5: 63.3: 23.7;
[0028] When the voxelized human body model is used for in vivo radionuclide contamination detection, the equivalent tissue fluid in the model unit block constituting the gastrointestinal organ is a radioactive specific activity of 1000 Bq / g. 137 Cs solution.
[0029] Further, preferably, the brain is composed of 12 model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0030] The heart is composed of 6 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0031] The lung is composed of 22 model unit blocks. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the lung composed of the model unit blocks is 0.38g / cm 3 ;
[0032] The oral and nasal cavity is composed of a model unit block. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the oral and nasal cavity composed of the model unit blocks is 0.38g / cm 3 ;
[0033] The stomach is composed of three model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0034] The small intestine is composed of 10 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0035] The colon is composed of 5 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0036] The liver is composed of 15 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0037] The gallbladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0038] The pancreas is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0039] The spleen is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0040] The kidney is composed of 4 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 4.61%;
[0041] The thymus is composed of one model unit block, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0042] The thyroid gland is composed of two model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0043] The bladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 9.22%.
[0044] The muscle is composed of 124 model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0045] The fat is composed of 109 model units, the cubic container is made of PP, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0046] The skeleton is composed of 53 model unit blocks, the cubic container is made of PTFE, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0047] In order to solve the above problem, the present invention further provides an electronic device, the electronic device comprising:
[0048] at least one processor; and,
[0049] a memory communicatively connected to the at least one processor; wherein,
[0050] The memory stores instructions that can be executed by the at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to perform the steps in the above-mentioned neutron dose assessment method based on voxelized human body model.
[0051] The present invention has the following beneficial effects by establishing a voxelized human body model and a neutron dose assessment method:
[0052] 1) The model unit blocks are filled with sodium solution, and the human body model composed of the model unit blocks includes major tissues and organs that are close to the volume, density, element content, and position of the real human body. Compared with the traditional simple geometric models used in irradiation experiments, such as three-dimensional water tanks, the dose generated by the human body model of the present invention after neutron irradiation is closer to the irradiation of the actual human body, and the dose of all major tissues and organs can be evaluated after one irradiation, without the need to irradiate each organ separately, which greatly improves the experimental efficiency;
[0053] 2) The human body model composed of model units filled with sodium solution can achieve a highly simulated and relatively accurate spatial distribution of sodium in the human body, and thus can be used to study the human body's sensory 24 The spatial distribution of Na activity;
[0054] 3) Compared with traditional solid models, the human body can be sensed by injecting and extracting sodium solution into the model unit blocks corresponding to each simulated organ. 24 Detection of Na activity; the model unit block has a simple and regular structure, with a uniform solution sample shape and measurement geometry; compared with the traditional radioactivity measurement of irregular organ models, the model unit block of the present invention has the technical effects of accurate calculation results and high detection efficiency;
[0055] 4) The human body model composed of model unit blocks can be modularly assembled and disassembled according to human body parameters, and the number and coordinate positions of the model unit blocks of each tissue and organ can be changed at will to be closer to the actual physiological structure of the human body irradiated by neutrons; it has a high degree of flexibility;
[0056] 5) Moreover, this model has low production cost, rich usage scenarios, can be applied to different irradiation experiment requirements, and has good application scalability. BRIEF DESCRIPTION OF THE DRAWINGS
[0057] Figure 1 A three-dimensional schematic diagram of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention;
[0058] Figure 2-A A front view of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention; Figure 2-B A left view of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention; Figure 2-C A top view of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention;
[0059] Figure 3 A schematic diagram of the structure of a model unit block in a voxelized human body model for neutron dose assessment irradiation experiment provided by an embodiment of the present invention;
[0060] Figure 4 A schematic diagram of the structure of a model unit block representing the lungs and oral and nasal cavities in a voxelized human body model for neutron dose assessment irradiation experiments provided by one embodiment of the present invention;
[0061] Figure 5 A comparison diagram of the whole body absorbed dose of a voxelized human body model for neutron dose assessment irradiation experiment provided by an embodiment of the present invention after being irradiated with different irradiation geometries of a californium-252 neutron source and an ICRP110 male phantom;
[0062] Figure 6 A comparison diagram of the absorbed dose of each tissue and organ of a voxelized human body model for neutron dose assessment irradiation experiment provided by an embodiment of the present invention after being irradiated by a californium-252 neutron source and an ICRP110 male phantom;
[0063] Figure 7 A comparison diagram of the whole body absorbed dose of a voxelized human body model for neutron dose assessment irradiation experiment and an ICRP110 male phantom as a function of neutron energy provided in one embodiment of the present invention;
[0064] Figure 8 Neutron induction comparison between a voxelized human body model and an ICRP110 male phantom for neutron dose assessment irradiation experiment provided by an embodiment of the present invention 24 Comparison chart of Na characteristic gamma-ray measurement counts.
[0065] Fig. 9 A schematic diagram of the internal structure of an electronic device for implementing a neutron dose assessment method based on a voxelized human body model provided by an embodiment of the present invention.
[0066] Among them, 1. model unit block; 11. cubic container body; 12. cover body; 13. partition wall; 14. central chamber; 15. peripheral chamber.
[0067] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0068] It should be understood that the specific embodiments described herein are only used to explain the present invention, and are not used to limit the present invention.
[0069] Example 1
[0070] The present invention discloses a voxelized human body model, wherein the human body model is composed of simulated organs according to the relative positions of organs in a real human body; the simulated organs are composed of model unit blocks stacked according to the human body parameters of a person to be irradiated; wherein the model unit blocks include a cubic container and an equivalent tissue solution filled in the cubic container.
[0071] When the organ to be simulated by the model unit block is the lung or oral and nasal cavity, the cubic container includes a hollow cube, in which a partition wall is arranged to divide the inner cavity of the cube into a central chamber and a peripheral chamber, the central chamber is filled with air, and the peripheral chamber is filled with equivalent tissue fluid.
[0072] Specifically, the human body model in the present invention is composed of a plurality of model unit blocks, like building blocks. Each model unit block is filled with equivalent tissue fluid, and the equivalent tissue fluid can be set according to the specific requirements of the irradiation experiment. For example, when studying neutron-induced 42 When Ca is radioactive, the solution in the cubic container of the model unit block corresponding to the bones is changed to 10% calcium nitrate solution, and the equivalent tissue fluid filled in the cubic containers of other model unit blocks is changed to water; when studying the gamma ray irradiation dose to the human body, the solution filled in the cubic container of the model unit block can be changed to equivalent tissue fluid with the main element ratio of hydrogen: nitrogen: oxygen: carbon = 10.5:2.5:63.3:23.7; when studying the contamination in the human body, the corresponding radioactive nuclide solution can be injected into the cubic container of the model unit block corresponding to the gastrointestinal organ, such as radioactive specific activity 1000Bq / g 137 Cs solution, etc.
[0073] In the specific implementation process, the material of the cubic container is polytetrafluoroethylene (PTFE) with a density of 2.2 g / cm 3 ; Organic glass (PMMA), density is 1.15g / cm 3 ; Polyethylene (PP), density 0.95g / cm 3 That is to say, all organs of the body can be composed of model unit blocks of the same material, or each organ can be made of a corresponding material according to its characteristics. For example, the brain organ is composed of model unit blocks of PMMA material, the lung organ is composed of model unit blocks of PP material, and the bone organ is composed of model unit blocks of PTFE material.
[0074] In the specific implementation process, the cubic container of the model unit block can be one or more of the following cubes: cylinder, tetrahedron, pentahedron, hexahedron, cone, sphere, etc., which are not specifically limited here; the combination of each model unit block can be stacked or can be locked together like building blocks, which are not specifically limited here. Since the cubic container is to be filled with equivalent tissue solution and the equivalent tissue solution needs to be extracted for detection, the cubic container cannot be an integrated closed one, but the solution needs to be injected and extracted according to actual needs. For example, the cubic container can be set as a separate container body and a cover; or the cubic container can also be provided with a detachable sealing plug for equivalent tissue fluid extraction or filling; furthermore, the cubic container can also be provided with an injection port that can be inserted by a needle syringe, and the needle syringe can assist in the extraction or filling of the equivalent tissue fluid; there is no specific limitation on the entry and exit method of the equivalent tissue fluid. In addition, the voxelized human body model can be composed of model unit blocks of uniform specifications; or different specifications of model unit blocks can be used for different organs. That is to say, all organs of the body can be composed of small cube model unit blocks of uniform specifications, or the brain organ can be composed of small cube model unit blocks of one specification; the gastrointestinal organs can be composed of small regular hexahedrons of another specification; and the liver organ can be composed of regular triangles of one specification.
[0075] The model unit blocks are filled with equivalent tissue solution, and the human body model composed of the model unit blocks includes major tissues and organs that are close to the volume, density, element content and position of the real human body. Compared with the traditional simple geometric models used in irradiation experiments, such as three-dimensional water tanks, the human body model of the present invention produces a dose that is closer to the actual human body after being irradiated, and the doses of all major tissues and organs can be evaluated after one irradiation without the need to irradiate each organ separately, which greatly improves the experimental efficiency; the human body model composed of the model unit blocks filled with equivalent tissue solution can achieve a highly simulated and more accurate spatial distribution of sodium elements in the human body, and then the spatial distribution of induced radiation in the human body can be studied; the human body model composed of the model unit blocks can be modularly assembled and disassembled according to human body parameters, and the number and coordinate position of the model unit blocks of each tissue and organ can be changed at will to be closer to the actual physiological structure of the irradiated human body; it has a high degree of flexibility.
[0076] Example 2
[0077] The present invention provides a neutron dose assessment method based on a voxelized human body model, and the method includes steps S110-S150.
[0078] S110, detect the human body parameters and neutron-induced 24 Na activity;
[0079] S120, based on the human body parameters of the irradiated person, using model unit blocks to stack and simulate various organs of the human body; combining the simulated organs according to the relative positions of the organs in the real human body to form a human body model; wherein the model unit blocks include a cubic container and a sodium solution filled in the cubic container;
[0080] S130, irradiating the human body model with a unit dose of neutrons according to the neutron energy distribution and irradiation geometric conditions of the irradiated person;
[0081] S140, using radiation detectors to detect neutrons in the human body model after neutron irradiation 24 Na activity was tested;
[0082] S150, based on the neutron induction of the human body model 24 Na activity, the neutron dose to the irradiated personnel is determined according to the following formula;
[0083] D1=(A1 / A0)·D0
[0084] Among them, D1 is the neutron dose of the exposed personnel; A1 is the neutron-induced 24 Na activity; A0 is the neutron-induced 24 Na activity; D0 is the unit dose of neutron irradiation.
[0085] It should be noted that, when in the scenario of neutron dose assessment, the equivalent tissue fluid is a sodium solution, and the sodium solution is one of sodium carbonate solution, sodium acetate solution, sodium lactate or sodium citrate, and the type of sodium solution is not specifically limited. However, the sodium solution includes a first concentration sodium solution, a second concentration sodium solution and a third concentration sodium solution with a sodium content ratio of 1:2:4; the first concentration sodium solution is used to fill the model unit blocks that constitute the brain, heart, lungs, oral and nasal cavity, stomach, small intestine, colon, gallbladder, pancreas, spleen, thymus, thyroid, muscle, fat and bone; the second concentration sodium solution is used to fill the model unit blocks that constitute the liver and kidneys; the third concentration sodium solution is used to fill the model unit blocks that constitute the bladder. In other words, it is necessary to set three sodium solutions with different sodium contents, and the sodium content ratio of the three sodium solutions must be 1:2:4. In the first group of examples, the first concentration of sodium solution is 0.23% by mass of Na2CO3, that is, the sodium content is 0.1%; the second concentration of sodium solution is 0.461% by mass of Na2CO3, that is, the sodium content is 0.2%; the third concentration of sodium solution is 0.922% by mass of Na2CO3, that is, the sodium content is 0.4%. In the second group of examples, the first concentration of sodium solution is 2.3% by mass of Na2CO3, that is, the sodium content is 1%; the second concentration of sodium solution is 4.61% by mass of Na2CO3, that is, the sodium content is 2%; the third concentration of sodium solution is 9.22% by mass of Na2CO3, that is, the sodium content is 4%. When the sodium content of the sodium solution of the first group of examples is used, the sodium content of the human body model is equivalent to the sodium content of the real organs of the human body. When the sodium content of the sodium solution of the second group of examples is used, the sodium content of the human body model is 10 times the sodium content of the real organs of the human body. Under the same neutron injection, the human body model produces 24 The Na activity is 10 times that of the real human body. Since the sodium content of each tissue and organ is increased proportionally, the sensitivity of the human body to neutron irradiation is increased, and the radiation effects of the human body can be studied at a lower neutron dose.
[0086] In the specific implementation process, after being irradiated by neutrons, the neutron-induced 24 Na activity; the containers in the model can also be taken out separately and the neutron induction of a single container can be detected using a radiation detector. 24 Na activity can be measured; the containers representing a certain tissue or organ can also be removed and the neutron induction of the corresponding tissue or organ can be detected using a radiation detector. 24 The Na2CO3 solution in the container can also be taken out and neutron induction can be performed using test tubes, Marlin cups and other containers. 24 Measurement of Na activity.
[0087] Multiple model units are set up to form a human body model similar to the human anatomy and containing major tissues and organs. The material of each cubic container is similar to the element composition and density of the corresponding tissue and organ. Solutions with different sodium contents are placed in the cubic containers to represent the sodium content of different tissues and organs of the human body. This model is suitable for studying the induced changes of human body after neutron exposure. 24 The relationship between Na activity and dose. Compared with simple models such as traditional three-dimensional water tanks, this model has the advantages of being closer to the real anatomical structure of the human body, high sensitivity to neutron irradiation, and individual evaluation of tissues and organs. In addition, this model can change the number and position coordinates of containers for each tissue and organ, and change the type and concentration of the solution filled according to the actual conditions such as the research purpose and the height and weight of the personnel to meet the needs of different experiments, and has good application scalability.
[0088] Example 3
[0089] Figure 1 2 and 3 provide an overall description of a voxelized human body model for neutron dose assessment irradiation experiments; Figure 1 A three-dimensional schematic diagram of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention; Figure 2-A A front view of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention; Figure 2-B A left view of a voxelized human body model for neutron dose assessment irradiation experiment provided by one embodiment of the present invention; Figure 2-C A top view of a voxelized human body model for neutron dose assessment irradiation experiment provided in accordance with an embodiment of the present invention.
[0090] The present invention discloses a voxelized human body model, wherein the human body model is composed of simulated organs according to the relative positions of organs in a real human body; the simulated organs are composed of model unit blocks stacked according to the human body parameters of a person to be irradiated; wherein the model unit blocks include a cubic container and an equivalent tissue solution filled in the cubic container.
[0091] like Figure 1 As shown in the figure, the human body is divided into 375 5cm×5cm×5cm model units. The cubic containers are made of different materials to simulate the density of different tissues and organs of the human body. Each cubic container is filled with solutions with different sodium contents to simulate the sodium content of different tissues and organs of the human body. The total mass of the model is 47.25kg, of which the container mass is 6.43kg and the mass of the sodium solution is 40.82kg. The human body model is 90cm high, 40cm at the widest point, 25cm at the thickest point, and has a total volume of 16875cm 3 .
[0092] The brain is composed of 12 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0093] The heart is composed of 6 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0094] The lung is composed of 22 model unit blocks. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the lung composed of the model unit blocks is 0.38g / cm 3 ;
[0095] The oral and nasal cavity is composed of a model unit block. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the oral and nasal cavity composed of the model unit blocks is 0.38g / cm 3 ;
[0096] The stomach is composed of three model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0097] The small intestine is composed of 10 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0098] The colon is composed of 5 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0099] The liver is composed of 15 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0100] The gallbladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0101] The pancreas is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0102] The spleen is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0103] The kidney is composed of 4 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 4.61%;
[0104] The thymus is composed of one model unit block, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0105] The thyroid gland is composed of two model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0106] The bladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 9.22%.
[0107] The muscle is composed of 124 model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0108] The fat is composed of 109 model units, the cubic container is made of PP, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%;
[0109] The skeleton is composed of 53 model unit blocks, the cubic container is made of PTFE, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
[0110] Taking the first model unit block at the right rear of the bottom of the human body model as the origin, from right to left is the X axis, from back to front is the Y axis, and from bottom to top is the Z axis. The position coordinate range of the main tissues and organs in the human body model is as follows:
[0111] Brain: X∈(12-27cm), Y∈(3-20cm), Z∈(80-90cm);
[0112] Heart: X∈(16-22cm), Y∈(11-25cm), Z∈(45-60cm);
[0113] Lung: X∈(5-32cm), Y∈(6-20cm), Z∈(45-65cm);
[0114] Oral and nasal cavity: X∈(17-32cm), Y∈(18-23cm), Z∈(80-85cm);
[0115] Stomach: X∈(11-21cm), Y∈(14-19cm), Z∈(35-45cm);
[0116] Small intestine: X∈(11-32cm), Y∈(8-24cm), Z∈(15-40cm);
[0117] Colon: X∈(6-27cm), Y∈(13-23cm), Z∈(25-40cm);
[0118] Liver: X∈(16-31cm), Y∈(4-24cm), Z∈(35-45cm);
[0119] Gallbladder: X∈(21-26cm), Y∈(9-19cm), Z∈(35-40cm);
[0120] Pancreas: X∈(16-21cm), Y∈(10-20cm), Z∈(35-40cm);
[0121] Spleen: X∈(6-11cm), Y∈(4-14cm), Z∈(40-45cm);
[0122] Kidney (left): X∈(27-32cm), Y∈(3-13cm), Z∈(30-35cm);
[0123] Kidney (right): X∈(7-12cm), Y∈(3-13cm), Z∈(30-35cm);
[0124] Thymus: X∈(17-22cm), Y∈(16-21cm), Z∈(60-65cm);
[0125] Thyroid: X∈(12-27cm), Y∈(13-18cm), Z∈(65-70cm);
[0126] Bladder: X∈(17.5-22.5cm), Y∈(14-24cm), Z∈(10-15cm);
[0127] Muscle: X∈(0-40cm), Y∈(1-25cm), Z∈(0-80cm);
[0128] Fat: X∈(0-40cm), Y∈(0-25cm), Z∈(0-85cm);
[0129] Skeleton: X∈(5-40cm), Y∈(0-24cm), Z∈(0-90cm).
[0130] Figure 3 and Figure 4The specific structure of the model unit block is described as a whole; among them, Figure 3 A schematic diagram of the structure of a model unit block in a voxelized human body model for neutron dose assessment irradiation experiment provided by an embodiment of the present invention; Figure 4 A schematic diagram of the structure of model unit blocks representing the lungs and oral and nasal cavities in a voxelized human body model for neutron dose assessment irradiation experiments provided by one embodiment of the present invention.
[0131] In this embodiment, the model unit block includes a cubic container and an equivalent tissue solution filled in the cubic container; the cubic container includes a cubic container body 11 and a cover 12. When the sodium solution needs to be injected, it is only necessary to remove the cover 12. After the sodium solution injection is completed, the cover 12 is closed to obtain a complete model unit block. A corresponding number of model unit blocks can be assembled into organs to be simulated of corresponding sizes. After neutron irradiation, if the sodium solution needs to be taken out to detect the radiation amount, the cover 12 of the model unit block is removed and the sodium solution in the cubic container body 11 is extracted.
[0132] In the specific implementation process, the cubic container is set to a cube with an outer size of 5cm×5cm×5cm and a wall thickness of 1mm; that is, the human body model in this embodiment is composed of cubic containers of uniform specifications; optimally, the size is set to 5cm×5cm×5cm, which can not only meet the corresponding size requirements of each organ to be simulated, but also make the assembled simulated organ close to the volume, density, element content, and position of the real human organ, thereby ensuring the detection accuracy of the human body model. Of course, the cubic container can also be set to a smaller size, then the number of model unit blocks will increase accordingly, which will bring great challenges to the difficulty of building the human body model and the stability of the stacked human body model.
[0133] In order to further improve the degree of simulation of simulated organs and thus improve the accuracy of radiation measurement, for organs such as the lungs or oral and nasal cavities where air exists, the structure of the model unit blocks used in the simulation is improved. Figure 4 As shown, when the organ to be simulated by the model unit block is the lung or the oral and nasal cavity, the cubic container includes a cubic container body 11 and a cover 12. The cubic container body 11 includes a hollow cube, and a partition wall 13 is arranged in the hollow cube to separate the inner cavity of the cube into a central chamber 14 and a peripheral chamber 15. The central chamber 14 is filled with air, and the peripheral chamber 15 is filled with a sodium solution. Optimally, the partition wall is 1 mm thick; the central chamber is 4.26 cm×4.26 cm×4.8 cm in space.
[0134] In this embodiment, a voxelized human body model for neutron dose assessment irradiation experiment is provided, and a digital human body model of an adult male provided in the International Commission on Radiation Protection Publication No. 110 (hereinafter referred to as ICRP110 male phantom) is used to conduct neutron irradiation dose and induced 24 The comparison of Na activity shows the following results:
[0135] like Figure 5 As shown, the human body model of the present invention and the adult male reference human calculation model proposed in the International Commission on Radiation Protection (ICRP) Publication No. 110 (referred to as ICRP110 male phantom) were irradiated with different irradiation geometries using a californium-252 neutron source, wherein AP is front irradiation, PA is back irradiation, LLAT is left irradiation, RLAT is right irradiation, ROT is rotational irradiation, and ISO is isotropic irradiation. The calculation results show that the whole body absorbed dose of the present model and the ICRP110 male phantom are similar under different irradiation geometries, and the maximum deviation is <3.05%.
[0136] like Figure 6 As shown, the human body model of the present invention and the ICRP110 male phantom were irradiated frontally using a californium-252 neutron source. The calculation results showed that the absorbed doses of the main tissues and organs of the human body model of the present invention and the ICRP110 male phantom were similar, with a maximum deviation of <9.52%.
[0137] like Figure 7 As shown, the human body model of the present invention and the ICRP110 male phantom were irradiated frontally with monoenergetic neutrons of different energies. The calculation results showed that the whole body absorbed dose of the human body model of the present invention and the ICRP110 male phantom varied in the same trend with the neutron energy, with a maximum deviation of <7.88%.
[0138] like Figure 8 As shown, after being irradiated by the californium-252 neutron source, the induced radiation emitted by the human body model of the present invention and the ICRP110 male body model was measured using a radiation detector. 24 The results show that the geometric detection efficiency of the human body model of the present invention is more than 70% higher than that of the ICRP110 male body model. Since the sodium content of the human body model of the present invention is 10 times that of a normal human body, under the same dose of neutron irradiation, the total detection efficiency of the human body model of the present invention is 22 times higher than that of the ICRP110 male body model.
[0139] The voxelized human body model and neutron dose assessment method of the present invention include major tissues and organs that are close to the volume, density, element content, and position of a real human body. Compared with the simple geometric body model used in traditional irradiation experiments, the dose generated by the voxelized human body model of the present invention after neutron irradiation is closer to the actual human body irradiation situation, and the dose of all major tissues and organs can be assessed after one irradiation without the need to irradiate each organ separately, which greatly improves the experimental efficiency; the voxelized human body model of the present invention uses small-volume containers (model unit blocks) of different materials to simulate the density of different tissues and organs of the human body, and each cubic container is filled with solutions with different sodium contents to simulate the sodium content of different tissues and organs of the human body, thereby providing a more accurate spatial distribution of sodium elements in the human body, which can be used to study the induction of human body. 24 The spatial distribution of Na activity, and the proportional increase in the sodium content of each tissue and organ, increased the sensitivity of the human body to neutron irradiation, and the irradiation effect of the human body can be studied at a lower neutron dose. Compared with the traditional solid model, the injection and extraction of the solution in the container can be carried out. 24 When measuring Na activity, a uniform solution sample shape and measurement geometry are given, rather than directly measuring the radioactivity of irregular tissue and organ models, to achieve neutron-induced 24 The voxelized human body model of the present invention can be modularly assembled and disassembled during use, and the number and position coordinates of the containers of each tissue and organ can be changed according to the actual situation of the height and weight of the human body irradiated by neutrons, so as to be closer to the actual physiological structure of the human body irradiated by neutrons; the container material, density, and the type and concentration of the solution filled can be changed to meet the needs of different irradiation experiments, and has good application scalability.
[0140] like Fig. 9 As shown, the present invention provides an electronic device 9 for a neutron dose assessment method based on a voxelized human body model.
[0141] The electronic device 9 may include a processor 90 , a memory 91 and a bus, and may also include a computer program stored in the memory 91 and executable on the processor 90 , such as a neutron dose assessment program 92 based on a voxelized human body model.
[0142] The memory 91 includes at least one type of readable storage medium, and the readable storage medium includes flash memory, mobile hard disk, multimedia card, card-type memory (for example: SD or DX memory, etc.), magnetic memory, disk, optical disk, etc. The memory 91 may be an internal storage unit of the electronic device 9 in some embodiments, such as a mobile hard disk of the electronic device 9. The memory 91 may also be an external storage device of the electronic device 9 in other embodiments, such as a plug-in mobile hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (SecureDigital, SD) card, a flash card (Flash Card), etc. equipped on the electronic device 9. Further, the memory 91 may also include both an internal storage unit of the electronic device 9 and an external storage device. The memory 91 may not only be used to store application software and various types of data installed in the electronic device 9, such as the code of the neutron dose assessment program based on the voxelized human body model, but also be used to temporarily store data that has been output or is to be output.
[0143] The processor 90 may be composed of an integrated circuit in some embodiments, for example, a single packaged integrated circuit, or a plurality of packaged integrated circuits with the same or different functions, including one or more central processing units (CPUs), microprocessors, digital processing chips, graphics processors, and combinations of various control chips, etc. The processor 90 is the control core (Control Unit) of the electronic device, and uses various interfaces and lines to connect various components of the entire electronic device, and executes or executes programs or modules (such as neutron dose assessment programs based on voxelized human models, etc.) stored in the memory 91, and calls data stored in the memory 91 to execute various functions of the electronic device 9 and process data.
[0144] The bus may be a peripheral component interconnect (PCI) bus or an extended industry standard architecture (EISA) bus, etc. The bus may be divided into an address bus, a data bus, a control bus, etc. The bus is configured to realize connection and communication between the memory 91 and at least one processor 90, etc.
[0145] Fig. 9 Only an electronic device with components is shown, and those skilled in the art will understand that Fig. 9The structure shown does not constitute a limitation on the electronic device 9, and may include fewer or more components than shown in the figure, or combine certain components, or arrange the components differently.
[0146] For example, although not shown, the electronic device 9 may also include a power source (such as a battery) for supplying power to each component. Preferably, the power source may be logically connected to the at least one processor 90 through a power management device, so that the power management device can realize functions such as charging management, discharging management, and power consumption management. The power source may also include any components such as one or more DC or AC power sources, recharging devices, power failure detection circuits, power converters or inverters, and power status indicators. The electronic device 9 may also include a variety of sensors, Bluetooth modules, Wi-Fi modules, etc., which will not be repeated here.
[0147] Furthermore, the electronic device 9 may also include a network interface. Optionally, the network interface may include a wired interface and / or a wireless interface (such as a WI-FI interface, a Bluetooth interface, etc.), which is generally used to establish a communication connection between the electronic device 9 and other electronic devices.
[0148] Optionally, the electronic device 9 may further include a user interface, which may be a display, an input unit (such as a keyboard), or a standard wired interface or a wireless interface. Optionally, in some embodiments, the display may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, and an OLED (Organic Light-Emitting Diode) touch device. The display may also be appropriately referred to as a display screen or a display unit, which is used to display information processed in the electronic device 9 and to display a visual user interface.
[0149] It should be understood that the embodiment is for illustration only and the scope of the patent application is not limited to this structure.
[0150] The neutron dose assessment program 92 based on the voxelized human body model stored in the memory 91 of the electronic device 9 is a combination of multiple instructions. When executed in the processor 90, the following can be achieved: S110, detecting the human body parameters of the irradiated person and the neutron-induced 24Na activity; S120, based on the human body parameters of the irradiated person, using model unit blocks to stack and simulate various organs of the human body; according to the relative positions of the organs in the real human body, the simulated organs are combined to form a human body model; wherein the model unit block includes a cubic container and a sodium solution filled in the cubic container; S130, according to the neutron energy distribution and irradiation geometric conditions of the irradiated person, the human body model is irradiated with a unit dose of neutrons; S140, using a radiation detector to detect the neutron induction of the human body model after neutron irradiation 24 Na activity is detected; S150, based on the neutron induction of the human body model 24 Na activity, the neutron dose of the exposed personnel is determined according to the following formula: D1 = (A1 / A0)·D0, where D1 is the neutron dose of the exposed personnel; A1 is the neutron induced 24 Na activity; A0 is the neutron-induced 24 Na activity; D0 is the unit dose of neutron irradiation.
[0151] Specifically, the specific implementation method of the processor 90 for the above instructions can refer to the description of the relevant steps in the corresponding embodiment of the above embodiment, which will not be repeated here. It should be emphasized that in order to further ensure the privacy and security of the above neutron dose assessment program based on the voxelized human body model, the above database can process data and store it in the node of the blockchain where the server cluster is located.
[0152] Furthermore, if the module / unit integrated in the electronic device 9 is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. The computer-readable medium may include: any entity or device capable of carrying the computer program code, a recording medium, a USB flash drive, a mobile hard disk, a magnetic disk, an optical disk, a computer memory, and a read-only memory (ROM).
[0153] The embodiment of the present invention further provides a computer-readable storage medium, which may be non-volatile or volatile, and stores a computer program, which, when executed by a processor, implements: S110, detecting human body parameters of an irradiated person and neutron-induced irradiation of the irradiated person; 24Na activity; S120, based on the human body parameters of the irradiated person, using model unit blocks to stack and simulate various organs of the human body; according to the relative positions of the organs in the real human body, the simulated organs are combined to form a human body model; wherein the model unit block includes a cubic container and a sodium solution filled in the cubic container; S130, according to the neutron energy distribution and irradiation geometric conditions of the irradiated person, the human body model is irradiated with a unit dose of neutrons; S140, using a radiation detector to detect the neutron induction of the human body model after neutron irradiation 24 Na activity is detected; S150, based on the neutron induction of the human body model 24 Na activity, the neutron dose of the exposed personnel is determined according to the following formula: D1 = (A1 / A0)·D0, where D1 is the neutron dose of the exposed personnel; A1 is the neutron induced 24 Na activity; A0 is the neutron-induced 24 Na activity; D0 is the unit dose of neutron irradiation. Specifically, the specific implementation method when the computer program is executed by the processor can refer to the description of the relevant steps in the neutron dose assessment method based on the voxelized human body model in the embodiment, which will not be repeated here.
[0154] That is to say, in the specific implementation process, the present invention integrates various functions into one hardware and sets up a human-computer interaction system. It only needs to manually input the neutron energy and irradiation geometry corresponding to the selected irradiated person, the height and weight data of the irradiated person and other irradiation data, and then automatically irradiate the built human body model, and then perform induction on the irradiated human body model. 24 The detection of Na activity can output the neutron dose of the irradiated personnel. The hardware data processing module automatically performs various calculations. During the entire test process, the test system can not only display the test results on the human-computer interaction module, but also export the results to files. Some test items can be analyzed and counted, that is, automatic comparison, automatic output of results and automatic statistical analysis are realized. It not only solves the problem of large amount of neutron dose detection data and long detection time in the prior art; it further weakens the professional requirements of neutron detection for operators, and greatly improves the accuracy and efficiency of neutron dose measurement.
[0155] In the several embodiments provided by the present invention, it should be understood that the disclosed devices, apparatuses and methods can be implemented in other ways. For example, the device embodiments described above are only schematic, for example, the division of the modules is only a logical function division, and there may be other division methods in actual implementation.
[0156] The modules described as separate components may or may not be physically separated, and the components shown as modules may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
[0157] In addition, each functional module in each embodiment of the present invention may be integrated into one processing unit, each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated unit may be implemented in the form of hardware or in the form of hardware plus software functional modules.
[0158] It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention.
[0159] Therefore, no matter from which point of view, the embodiments should be regarded as illustrative and non-restrictive, and the scope of the present invention is limited by the appended claims rather than the above description, so it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any attached figure mark in the claims should not be regarded as limiting the claims involved.
[0160] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the present invention.
Claims
1. A neutron dose assessment method based on a voxelized human body model, characterized in that: Methods include, Detection of human parameters and neutron-induced 24 Na activity; Based on the human body parameters of the irradiated person, various organs of the human body are simulated by stacking model unit blocks; the simulated organs are combined to form a human body model according to the relative positions of the organs in the real human body; wherein the model unit block includes a cubic container and a sodium solution filled in the cubic container; the organ includes at least one of the brain, heart, lung, oral and nasal cavity, stomach, small intestine, colon, liver, gallbladder, pancreas, spleen, kidney, thymus, thyroid, bladder, muscle, fat, and bone; irradiating the human body model with a unit dose of neutrons according to the neutron energy distribution and irradiation geometric conditions of the neutron irradiated personnel; Using radiation detectors to detect neutron induction in a human body model after neutron irradiation 24 Na activity was tested; Based on the human body model neutron induction 24 Na activity, the neutron dose to the irradiated personnel is determined according to the following formula; D I =(A I / A0)·D0 Among them, D1 is the neutron dose of the exposed personnel; A1 is the neutron-induced 24 Na activity; A0 is the neutron-induced 24 Na activity; D0 is the unit dose of neutron irradiation.
2. The neutron dose assessment method based on voxelized human body model according to claim 1, characterized in that: When the organ to be simulated by the model unit block is the lung or the oral and nasal cavity, the cubic container includes a hollow cube, in which a partition wall is arranged to divide the inner cavity of the cube into a central chamber and a peripheral chamber, the central chamber is filled with air, and the peripheral chamber is filled with a sodium solution.
3. The neutron dose assessment method based on voxelized human body model according to claim 2, characterized in that: The cubic container is a cube with outer dimensions of 5cm×5cm×5cm and a wall thickness of 1mm; the partition wall is 1mm thick; and the central cavity is a space of 4.26cm×4.26cm×4.8cm.
4. The neutron dose assessment method based on voxelized human body model according to claim 1, characterized in that: The cubic container is made of polytetrafluoroethylene, organic glass or polyethylene.
5. The neutron dose assessment method based on voxelized human body model according to claim 1, characterized in that: The sodium solution is one of sodium carbonate solution, sodium acetate solution, sodium lactate or sodium citrate.
6. The neutron dose assessment method based on voxelized human body model according to claim 1, characterized in that: The sodium solution comprises a first concentration sodium solution, a second concentration sodium solution and a third concentration sodium solution with a sodium content ratio of 1:2:4; the first concentration sodium solution is used to fill model unit blocks constituting the brain, heart, lungs, oral and nasal cavity, stomach, small intestine, colon, gallbladder, pancreas, spleen, thymus, thyroid, muscle, fat and bone; The second concentration sodium solution is used to fill the model unit blocks that make up the liver and kidneys; The third concentration sodium solution is used to fill the model unit blocks that constitute the bladder.
7. A voxelized human body model, characterized in that: The human body model is composed of simulated organs according to the relative positions of organs in a real human body; the simulated organs are composed of model unit blocks stacked according to the human body parameters of the person to be irradiated; wherein the model unit blocks include a cubic container and an equivalent tissue solution filled in the cubic container; the organs include at least one of the brain, heart, lung, oral and nasal cavity, stomach, small intestine, colon, liver, gallbladder, pancreas, spleen, kidney, thymus, thyroid, bladder, muscle, fat, and bone; The voxelized human body model is applied to the neutron dose assessment method based on the voxelized human body model as claimed in any one of claims 1 to 6.
8. The voxelized human body model according to claim 7, wherein: When the voxelized human body model is applied to neutron irradiation induced 24 When Na activity is measured, the equivalent tissue fluid is a sodium solution; When the voxelized human body model is applied to neutron-induced 42 During the Ca radioactivity test, the equivalent tissue fluid in the model unit blocks constituting the bones is 10% calcium nitrate solution, and the equivalent tissue fluid in the model unit blocks constituting organs other than bones is water; When the voxelized human body model is applied to the gamma ray irradiation dose detection of the human body, the element ratio of the equivalent tissue fluid is hydrogen: nitrogen: oxygen: carbon = 10.5: 2.5: 63.3: 23.7; When the voxelized human body model is used for in vivo radionuclide contamination detection, the equivalent tissue fluid in the model unit block constituting the gastrointestinal organ is a radioactive specific activity of 1000 Bq / g. 137 Cs solution.
9. The voxelized human body model according to claim 7, wherein: The brain is composed of 12 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The heart is composed of 6 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The lung is composed of 22 model unit blocks. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the lung composed of the model unit blocks is 0.38g / cm 3 ; The oral and nasal cavity is composed of a model unit block. The cubic container includes a hollow cube, and a partition wall is arranged in the hollow cube to divide the inner cavity of the cube into a central cavity and a peripheral cavity. The material of the hollow cube and the partition wall is PP; the central cavity is filled with air, and the peripheral cavity is filled with a Na2CO3 solution with a mass fraction of 2.3%; the overall density of the oral and nasal cavity composed of the model unit blocks is 0.38g / cm 3 ; The stomach is composed of three model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%. The small intestine is composed of 10 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The colon is composed of 5 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The liver is composed of 15 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The gallbladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%. The pancreas is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The spleen is composed of two model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The kidney is composed of 4 model units, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 4.61%; The thymus is composed of one model unit block, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The thyroid gland is composed of two model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The bladder is composed of two model units. The cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 9.22%. The muscle is composed of 124 model unit blocks, the cubic container is made of PMMA, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The fat is composed of 109 model units, the cubic container is made of PP, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%; The skeleton is composed of 53 model unit blocks, the cubic container is made of PTFE, and the equivalent tissue fluid is a Na2CO3 solution with a mass fraction of 2.3%.
10. An electronic device, characterized in that: The electronic device comprises: at least one processor; and, a memory communicatively connected to the at least one processor; wherein, The memory stores instructions executable by the at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to perform the steps of the neutron dose assessment method based on a voxelized human body model as described in any one of claims 1 to 6.