A processing system for detecting microbial solutions

By designing a microbial solution detection and processing system including a three-axis motion module, a pipetting mechanism and a capping mechanism, the time-consuming and labor-intensive and inaccurate problems caused by relying on labor in microbial solution detection operations are solved, and the automation of the detection process and the accuracy of the results are improved.

CN118909751BActive Publication Date: 2025-06-06SICHUAN LIGHT INDUSTRY RESEARCH AND DESIGN INST +1
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Patent Information

Application Number
CN202410979386.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-07-22
Publication Date
2025-06-06
Estimated Expiration
2044-07-22

AI Technical Summary

Technical Problem

Microbial solution detection operation relies on manual labor, is time-consuming and labor-intensive, and can easily lead to inaccurate detection results. The existing equipment can only automate a single operation and cannot fully automate the entire detection process.

Method used

A treatment system for microbial solution detection is designed, including a three-axis motion module, a pipetting mechanism, a capping mechanism and multiple placement areas. Through these components, the automatic sampling, transfer, filtration and the tightening and opening of the bottle cap are realized, so as to automate the detection process.

Benefits of technology

By automating the microbial solution detection operation process, the time and error rate of manual operation are significantly reduced, and the accuracy and efficiency of the detection results are improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a processing system for detecting microbial solutions, which relates to the technical field of microbial solution processing and can solve the problem that most of the current operation processes of microbial solution detection operations rely entirely on manual labor, which is time-consuming and labor-intensive, and the detection results are inaccurate. A processing system for detecting microbial solutions according to an embodiment of the present invention comprises a frame and two sets of three-axis motion modules arranged on the frame, as well as at least one set of pipetting mechanisms and at least one set of capping mechanisms, wherein the pipetting mechanisms and the capping mechanisms are respectively arranged at the output ends of the two sets of three-axis motion modules; comprising a first placement area, a second placement area and a third placement area distributed below the two sets of three-axis motion modules in the horizontal direction, wherein the first placement area, the second placement area and the third placement area are respectively provided with a first slide, a second slide and a third slide that can slide in the longitudinal direction; comprising a mother solution test tube rack, a sample test tube rack and an injection bottle rack respectively placed on the first slide, the second slide and the third slide.
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Description

Technical Field

[0001] The invention relates to the technical field of microbial solution processing, and in particular to a processing system for microbial solution detection. Background Art

[0002] In the actual operation of microbial solution testing, it is often necessary to sterile filter the microbial solution to obtain pure microbial samples, or remove microorganisms for certain chemical and physical tests. Traditional filtration methods usually rely on manual operations, which are not only time-consuming and labor-intensive, but also prone to cross-contamination and sample contamination, affecting the accuracy of the test results.

[0003] In addition, when conducting microbial solution testing, the number of samples is usually large. Due to the large workload and high repetitiveness, it is very easy to make false detections or missed detections. The existing equipment for microbial solution testing can usually only automate a single operation, such as pipetting, extracting sample liquid, and screwing on the cap. As a result, a large amount of manpower is still required in the entire microbial solution testing process. Therefore, there is an urgent need for a device that can automate part of the process or the entire process in the microbial solution testing operation process.

[0004] Based on the above background, the inventors have designed a processing system for detecting microbial solutions to solve the above problems, and thus proposed the present application. Summary of the invention

[0005] The purpose of the present application is to provide a processing system for microbial solution detection, which is used to solve the problem that most of the current microbial solution detection operations rely entirely on manual labor, which is time-consuming and labor-intensive, and easily leads to inaccurate detection results.

[0006] The sampling and transfer of microbial solutions require manual operations.

[0007] In order to solve the above technical problems, the present invention adopts the following solutions:

[0008] The present application provides a processing system for detecting microbial solutions, comprising a frame and two sets of three-axis motion modules arranged on the frame, and at least one set of pipetting mechanism and at least one set of capping mechanism, wherein the pipetting mechanism and the capping mechanism are respectively arranged at the output ends of the two sets of three-axis motion modules;

[0009] It also includes a first placement area, a second placement area and a third placement area distributed in the transverse direction below the two sets of three-axis motion modules, and the first placement area, the second placement area and the third placement area are respectively provided with a first slide table, a second slide table and a third slide table that can slide in the longitudinal direction;

[0010] It also includes a mother liquid test tube rack, a sample test tube rack and a sample injection bottle rack which are respectively placed on the first slide, the second slide and the third slide.

[0011] Optionally, the capping mechanism includes an inverted capping motor, a connecting flange, and a capping cylinder fixed to the capping motor via the connecting flange;

[0012] The capping motor is a stepping motor or a servo motor;

[0013] The capping cylinder is a rotating finger cylinder;

[0014] The capping mechanism also includes a vertical mounting plate vertically arranged at the output end of the three-axis motion module, and the capping motor is invertedly arranged on the output end of the three-axis motion module through the vertical mounting plate.

[0015] Optionally, the first slide is further provided with a gun tip storage rack for storing at least two specifications of gun tips, and a waste gun storage box;

[0016] The gun head storage rack and the waste gun storage box are both located on a side of the first slide away from the second slide.

[0017] Optionally, it also includes a tube cover storage rack arranged on the second slide;

[0018] The tube cap storage rack is provided with a plurality of tube cap placement slots for placing the tube caps;

[0019] The pipe cover placement groove is circular, and a pipe cover pushing hole with a diameter smaller than the diameter of the pipe cover placement groove is arranged at the bottom thereof.

[0020] Optionally, it also includes a filter membrane storage rack and a bottle cap storage rack arranged on the third slide;

[0021] A plurality of filter membrane placement slots and bottle cap placement slots are respectively arranged on the filter membrane storage rack and the bottle cap storage rack;

[0022] The filter membrane placement slot and the bottle cap placement slot are both circular;

[0023] A filter membrane pushing hole with a diameter smaller than that of the filter membrane placement groove is provided at the bottom of the filter membrane placement groove;

[0024] A bottle cap pushing hole with a diameter smaller than the diameter of the bottle cap placing groove is arranged at the bottom of the bottle cap placing groove.

[0025] Optionally, it also includes at least two sets of storage rack discharging drives respectively arranged on the second slide and the third slide, and the storage rack discharging drive includes a vertically arranged pushing rod used to drive the discharge of materials in the tube cap placement slot, the filter membrane placement slot, and the bottle cap placement slot.

[0026] Optionally, it further includes a slide drive for driving the first slide, the second slide, and the third slide to move longitudinally;

[0027] The slide drive is a linear drive structure;

[0028] The mother liquid test tube rack, the sample test tube rack and the injection bottle rack are all located at the front side of the first slide, the second slide and the third slide away from the slide drive.

[0029] Optionally, a filter membrane mounting frame is further provided on the third slide, and a plurality of filter membrane placement points for individually placing filter membrane materials are provided on the filter membrane mounting frame.

[0030] Optionally, two sets of three-axis motion modules are distributed vertically up and down;

[0031] The frame includes two frame side panels arranged in parallel, and the three-axis operation module includes two longitudinal guide rails arranged on the frame side panels, and transverse guide rods with two ends respectively arranged on the two longitudinal guide rails, and vertical guide rails are arranged on the transverse guide rods, and the pipetting mechanism and the screw capping mechanism are arranged on the vertical guide rails.

[0032] Optionally, the mother solution test tube rack, sample test tube rack and injection bottle rack are all components with locking structures.

[0033] Optionally, the pipetting mechanism includes a mounting plate for vertically setting on the three-axis motion module, a linear drive assembly invertedly fixed on the mounting plate, and a gun holster for mounting a sampling gun head;

[0034] The holster is arranged vertically, and a connection structure is provided at the bottom of the holster for detachable connection with at least two types of gun heads;

[0035] It also includes a piston rod fixed to the output end of the linear drive assembly, and the piston rod is inserted into the holster and slidably connected with the holster.

[0036] Optionally, a gun head mounting groove having a size smaller than the inner diameter of the gun head is provided at the bottom of the gun holster;

[0037] The gun head mounting groove is sleeved and fixed with a first elastic ring protrusion and a second elastic ring protrusion. The first elastic ring protrusion is located below the second elastic ring protrusion, and the outer diameter of the second elastic ring protrusion is greater than the outer diameter of the first elastic ring protrusion.

[0038] Optionally, the bottom of the holster is further provided with a mounting cone surface located below the gun head mounting groove;

[0039] The diameter of the top of the mounting cone is smaller than the outer diameter of the first elastic ring protrusion.

[0040] Optionally, the linear drive assembly includes an inverted drive motor and a pipetting screw arranged on an output shaft of the drive motor;

[0041] It also includes a slider connected to the mounting plate in a vertical sliding direction, and a threaded sleeve fixed on the slider, wherein the threaded sleeve is sleeved on the pipetting screw;

[0042] The top of the piston rod is fixed to the slider.

[0043] Optionally, it further includes two bearings respectively fixed to the top and bottom of the mounting plate, and a mounting block disposed between the two bearings;

[0044] The mounting block is located below the slider, a through hole for the pipetting screw to pass through is provided on the mounting block, and the holster is fixed on the mounting block;

[0045] The output shaft of the driving motor is arranged on the bearing at the top, and a rotating shaft is fixed at the bottom of the pipetting screw, and the rotating shaft is rotatably connected to the bearing at the bottom.

[0046] Beneficial effects of the present invention:

[0047] 1. The present application sets up a capping mechanism, a pipetting mechanism, a three-axis motion module, and three placement areas, and the mother liquid test tube rack, the sample test tube rack and the injection bottle rack are placed under the two sets of three-axis motion modules through the first slide, the second slide and the third slide. The pipetting mechanism can be used to realize automatic extraction and discharge of sample mother liquid, sample reaction liquid, and installation of filter membranes, and the capping mechanism can be used to realize the transfer of bottle caps, tube caps, filter membrane materials, tightening and unscrewing bottle caps, taking out and installing tube caps, etc., and cooperate with two sets of three-axis motion modules. Most of the processes of the microbial solution detection operation process can be automated, which can effectively solve the problem that a large number of current operation processes need to rely on manpower, resulting in inaccurate test results.

[0048] 2. The first slide, the second slide and the third slide of the present application are arranged in the first placement area, the second placement area and the third placement area, especially the gun tip storage rack and the waste gun storage box are placed on the first slide, the tube cover storage rack is arranged on the second slide, and the filter membrane storage rack and the bottle cap storage rack are arranged on the third slide, so that in the entire microbial solution detection operation process of the present application, the pipetting mechanism and the screw cap mechanism follow the patrol path of the microbial solution detection operation process more simply, avoiding the problem of repeated movement of the pipetting mechanism and the screw cap in the three placement areas during a single detection process.

[0049] 3. The present application designs a special pipetting mechanism, the bottom of which can be detachably connected to at least two types of gun tips, so that the pipetting mechanism of the present application can draw sample mother solution into the sample test tube when one type of gun tip is connected, and can draw sample reaction solution from the sample test tube after connecting another type of gun tip, and before releasing the sample reaction solution into the sample bottle, a filter membrane is pressed onto the gun tip, thereby realizing the automated operation process of drawing, transferring, filtering and the like of two sample solutions by a single pipetting mechanism, thereby solving the problem that it is currently difficult for a single pipetting mechanism to complete the automated operation of microbial solutions.

[0050] 4. This application sets up three slides so that the operator can automatically slide out the corresponding slide when placing sample mother liquid, gun tip, sample bottle, and taking sample test tube, etc., to prevent the operator from putting his hands or body under the three-axis motion module to avoid safety hazards. BRIEF DESCRIPTION OF THE DRAWINGS

[0051] Figure 1 It is a schematic diagram of the three-dimensional structure of an embodiment of the present application.

[0052] Figure 2 It is a schematic diagram of the top structure of an embodiment of the present application.

[0053] Figure 3 It is a schematic diagram of the three-dimensional structure of the screw capping mechanism in the embodiment of the present application.

[0054] Figure 4 It is a schematic diagram of the three-dimensional structure of the pipetting mechanism in the embodiment of the present application.

[0055] Figure 5 for Figure 4 Schematic diagram of the cross-sectional structure of AA.

[0056] Figure 6 It is a schematic diagram of the three-dimensional structure of the locking frame in the embodiment of the present application.

[0057] Figure 7 It is a bottom view structural schematic diagram of the locking plate in the embodiment of the present application.

[0058] Description of reference numerals: 100-pipette mechanism, 11-drive motor, 12-pipette screw, 13-mounting plate, 14-bearing, 15-threaded sleeve, 16-slider, 17-mounting block, 18-piston rod, 19-holster, 191-gun head mounting groove, 192-first elastic ring convex, 193-second elastic ring convex, 194-mounting cone, 200-screw cap mechanism, 21-screw cap motor, 22-screw cap cylinder, 23-connecting flange, 24-vertical mounting plate, 311-frame side plate, 312-longitudinal guide rail, 313-transverse guide rod, 4-first slide, 41-mother liquid test tube rack, 42-gun tip storage rack, 43-waste gun storage box, 5-second slide, 51-sample test tube rack, 511-well plate, 512-bottom plate, 513-support column, 514-locking plate, 515-rolling element, 516-longitudinal rod, 517-cross rod, 518-rolling groove, 519-C-shaped support, 52-tube cap storage rack, 6-third slide, 61-injection bottle rack, 62-filter membrane storage rack, 63-bottle cap storage rack, 64-filter membrane mounting rack, 71-slide drive, 72-storage rack discharge drive. DETAILED DESCRIPTION

[0059] The present invention will be further described in detail below in conjunction with embodiments and drawings, but the embodiments of the present invention are not limited thereto.

[0060] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "longitudinal", "lateral", "horizontal", "inside", "outside", "front", "back", "top", "bottom" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the inventive product is usually placed when used. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present invention.

[0061] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "disposed", "opened", "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0062] The present invention will be described in detail below with reference to the accompanying drawings and in combination with embodiments.

[0063] like Figure 1 and Figure 7As shown, this embodiment provides a processing system for detecting a microbial solution, comprising a frame and two sets of three-axis motion modules arranged on the frame, and at least one set of pipetting mechanism 100 and at least one set of capping mechanism 200, wherein the pipetting mechanism 100 and the capping mechanism 200 are respectively arranged at the output ends of the two sets of three-axis motion modules;

[0064] It also includes a first placement area, a second placement area and a third placement area distributed in the transverse direction below the two sets of three-axis motion modules, and the first placement area, the second placement area and the third placement area are respectively provided with a first slide 4, a second slide 5 and a third slide 6 that can slide in the longitudinal direction;

[0065] It also includes a mother liquid test tube rack 41, a sample test tube rack 51 and a sample injection bottle rack 61 which are placed on the first slide 4, the second slide 5 and the third slide 6 respectively.

[0066] In this embodiment, a capping mechanism 200, a pipetting mechanism 100, a three-axis motion module, and three placement areas are provided, and a mother liquid test tube rack 41, a sample test tube rack 51, and a sample injection bottle rack 61 are placed under two sets of three-axis motion modules through a first slide 4, a second slide 5, and a third slide 6. The pipetting mechanism 100 can be used to realize automatic extraction and discharge of sample mother liquid, sample reaction liquid, and filter membrane installation, and the capping mechanism 200 can be used to realize operations such as transferring bottle caps, tube caps, and filter membrane materials, tightening and unscrewing bottle caps, and taking out and installing tube caps. In conjunction with two sets of three-axis motion modules, most of the processes of the microbial solution detection operation process can be automated, which can effectively solve the problem that a large number of current operation processes need to rely on manpower, are time-consuming and labor-intensive, and are prone to erroneous operations, resulting in inaccurate detection results.

[0067] In addition, the first slide 4, the second slide 5 and the third slide 6 of the present embodiment are arranged in the first placement area, the second placement area and the third placement area, especially the gun tip storage rack 42 and the waste gun storage box 43 are placed on the first slide 4, the tube cap storage rack 52 is arranged on the second slide 5, and the filter membrane storage rack 62 and the bottle cap storage rack 63 are arranged on the third slide 6, so that in the entire microbial solution detection operation process of the present application, the pipetting mechanism 100 and the screw cap mechanism 200 follow the patrol path of the microbial solution detection operation process more simply, avoiding the problem of repeated movement of the pipetting mechanism 100 and the screw cap in the three placement areas during a single detection process.

[0068] Specifically, in this embodiment, if Figure 3 As shown, the capping mechanism 200 includes an inverted capping motor 21, a connecting flange 23, and a capping cylinder 22 fixed to the capping motor 21 through the connecting flange 23;

[0069] The capping motor 21 is a stepping motor or a servo motor;

[0070] The capping cylinder 22 is a rotating finger cylinder;

[0071] The cap rotating mechanism 200 further includes a vertical mounting plate 24 vertically disposed at the output end of the three-axis motion module, and the cap rotating motor 21 is invertedly disposed at the output end of the three-axis motion module via the vertical mounting plate 24 .

[0072] The capping motor 21 in this embodiment is a stepping motor. The stepping motor and the rotating finger cylinder are both existing conventional equipment and will not be described in detail here.

[0073] Specifically, in this embodiment, if Figure 2 As shown, the first slide 4 is also provided with a gun tip storage rack 42 for storing at least two specifications of gun tips, and a waste gun storage box 43;

[0074] The gun tip storage rack 42 and the waste gun storage box 43 are both located on a side of the first slide 4 away from the second slide 5 .

[0075] The gun tip storage rack 42 and the waste gun storage box 43 are both arranged on a side of the first slide 4 away from the second slide 5 .

[0076] During the entire solution detection process, the action flow of the pipetting mechanism 100 is as follows: first, the pipetting mechanism 100 installs a gun tip of the first specification, then moves horizontally to the top of the mother liquid test tube rack 41, extracts a portion of the sample mother liquid, then moves to the top of the sample test tube rack 51 in the second placement area, releases the sample mother liquid into the sample test tube, then moves to the first placement area to remove the gun tip of the first specification, then installs the gun tip of the second specification, then moves to the top of the sample test tube rack 51 in the second placement area, extracts a portion of the sample reaction liquid after centrifugal vortex vibration, then moves to the third placement area, installs the filter membrane, and then releases the sample reaction liquid into the sample bottle, then moves to the first placement area to remove the gun tip of the second specification. At this time, the single operation process of the pipetting mechanism 100 is completed.

[0077] Therefore, referring to the action sequence and the circuit path of the above-mentioned pipetting mechanism 100, the gun tip storage rack 42 and the waste gun storage box 43 in this embodiment are both arranged on the side of the first slide 4 away from the second slide 5. The design concept is that in the processing process of the entire microbial solution detection process, the gun tip installation action and the gun tip disassembly action after multiple pipetting operations are completed of the pipetting mechanism 100 are the initial and final actions. Therefore, it is arranged on the side of the first slide 4 away from the second slide 5, so that the gun tip installation action and the gun tip disassembly action form a matching correspondence with the circuit path of the entire pipetting mechanism 100 in the detection process, so that the moving path of the pipetting mechanism 100 is more optimized, simple and reliable.

[0078] Specifically, in this embodiment, if Figure 2As shown, it also includes a tube cover storage rack 52 disposed on the second slide 5;

[0079] The tube cap storage rack 52 is provided with a plurality of tube cap placement slots for placing tube caps;

[0080] The tube cap placement groove is circular, and a tube cap pushing hole with a diameter smaller than the tube cap placement groove is provided at its bottom. In this embodiment, the tube cap storage rack 52 is provided on the second slide 5, which can reduce the moving distance of the capping mechanism 200, save process time, and improve detection efficiency.

[0081] Specifically, in this embodiment, if Figure 2 As shown, it also includes a filter membrane storage rack 62 and a bottle cap storage rack 63 arranged on the third slide 6;

[0082] The filter membrane storage rack 62 and the bottle cap storage rack 63 are respectively provided with a plurality of filter membrane placement slots and bottle cap placement slots;

[0083] The filter membrane placement slot and the bottle cap placement slot are both circular;

[0084] A filter membrane pushing hole with a diameter smaller than that of the filter membrane placement groove is provided at the bottom of the filter membrane placement groove;

[0085] The bottom of the bottle cap placement groove is provided with a bottle cap pushing hole with a diameter smaller than the diameter of the bottle cap placement groove. In this embodiment, the filter membrane storage rack and the bottle cap storage rack 63 are arranged on the third slide 6, which can reduce the moving distance of the capping mechanism 200, save process time, and improve detection efficiency.

[0086] Specifically, in this embodiment, it also includes at least two sets of storage rack discharge drives 72 respectively arranged on the second slide 5 and the third slide 6. The storage rack discharge drive 72 includes a vertically arranged pushing rod for driving the discharge of materials in the tube cap placement slot, the filter membrane placement slot, and the bottle cap placement slot.

[0087] The storage rack discharging drive 72 in this embodiment is a linear drive mechanism, and a push rod is provided at its output end. After the storage rack discharging drive 72 is started, the push rod can be used to push out the materials in the pipe cover placement slot, the filter membrane placement slot, and the bottle cap placement slot, and then the screw cap mechanism 200 can be used to grab and transfer the materials.

[0088] Specifically, in this embodiment, if Figure 2 As shown, it also includes a slide drive 71 for driving the first slide 4, the second slide 5, and the third slide 6 to move longitudinally;

[0089] The slide drive 71 is a linear drive structure;

[0090] The mother liquid test tube rack 41, the sample test tube rack 51 and the injection bottle rack 61 are all located at the front side of the first slide 4, the second slide 5, and the third slide 6 away from the slide drive 71. The mother liquid test tube rack 41, the sample test tube rack 51 and the injection bottle rack 61 are located at the front side of the three slides, which is convenient for subsequent placement of the mother liquid test tube rack 41, the sample test tube rack 51 and the injection bottle rack 61.

[0091] Specifically, in this embodiment, a filter membrane mounting frame 64 is further provided on the third slide 6, and a plurality of filter membrane placement points for placing filter membrane materials separately are provided on the filter membrane mounting frame 64. By providing the filter membrane placement points, it is convenient to set the filter membrane on the pipetting mechanism 100.

[0092] Specifically, in this embodiment, if Figure 1 As shown, two sets of three-axis motion modules are distributed vertically up and down;

[0093] The frame includes two frame side plates 311 arranged in parallel, and the three-axis operation module includes two longitudinal guide rails 312 arranged on the frame side plates 311, and transverse guide rods 313 with two ends respectively arranged on the two longitudinal guide rails 312, and the transverse guide rods 313 are provided with vertical guide rails, and the liquid transfer mechanism 100 and the capping mechanism 200 are arranged on the vertical guide rails. The three-axis operation module is a conventional structure and is not described in detail here.

[0094] Specifically, in this embodiment, the mother solution test tube rack 41, the sample test tube rack 51 and the injection bottle rack 61 are all components with locking structures, which facilitate the locking of the sample test tube, the sample bottle and the mother solution test tube when the capping mechanism 200 is capping.

[0095] refer to Figure 6 As shown, Figure 6 is a schematic diagram of the three-dimensional structure of the sample test tube rack 51, Figure 7 : is a schematic diagram of the structure of the locking plate 514 when viewed from above. The locking plate 514 is driven to move longitudinally by a linear drive mechanism to compress the sample test tube rack 51. The mother liquid test tube rack 41 and the sample test tube rack 51 in this embodiment have the same structure. The difference is that the mother liquid test tube rack 41 and the sample test tube rack 51 have different sizes such as tube diameters, resulting in different specific sizes of the mother liquid test tube rack 41 and the sample test tube rack 51. The technicians can set them according to the needs.

[0096] Since one portion of the sample reaction liquid needs to be released into two sample bottles when the pipetting mechanism 100 releases the sample reaction liquid into the sample bottle, the width dimension of the injection bottle rack 61 and the number of sample bottles that can be accommodated are different. In this embodiment, the number of sample bottles that can be accommodated by the injection bottle rack 61 is twice the number of sample test tubes that can be accommodated by the sample test tube rack 51.

[0097] like Figure 6As shown, in this embodiment, the sample test tube rack 51 includes a horizontally arranged and vertically distributed well plate 511 and a bottom plate 512, and a support column 513 for supporting the well plate 511. The well plate 511 and the bottom plate 512 are fixedly connected by the support column 513. The well plate 511 is provided with multiple rows of circular holes evenly distributed along the longitudinal direction for placing sample test tubes. The multiple rows of circular holes evenly distributed along the longitudinal direction are distributed in an array.

[0098] It also includes a locking plate 514 disposed between the orifice plate 511 and the bottom plate 512;

[0099] A rolling member 515 is provided between the locking plate 514 and the bottom plate 512. The locking plate 514 is movably connected to the top plate through the rolling member 515. The output end of the linear drive mechanism abuts against the end surface of the locking plate 514, and the locking plate 514 is driven to move to lock the sample tube.

[0100] The locking plate 514 includes two longitudinal rods 516 and a plurality of transverse rods 517 . The two ends of the transverse rods 517 are respectively fixed on the two longitudinal rods 516 . The plurality of transverse rods 517 are arranged at intervals, and the transverse rods 517 are arranged in an alternating manner with the rows of holes on the orifice plate 511 .

[0101] A plurality of rolling grooves 518 for placing the rolling elements 515 are provided at the bottom of the locking plate 514 and the top of the top plate. The length of the rolling grooves 518 is less than the distance between the two cross bars 517 .

[0102] The side of the cross bar 517 is also provided with a plurality of C-shaped supports 519 corresponding to the circular holes on the orifice plate 511 to improve the fixed support effect.

[0103] Specifically, in this embodiment, if Figure 4 and Figure 5 As shown, the pipetting mechanism 100 includes a mounting plate 13 vertically arranged on the three-axis motion module, a linear drive assembly invertedly fixed on the mounting plate 13, and a gun holster 19 for mounting a sampling gun head;

[0104] The holster 19 is arranged vertically, and a connection structure is provided at the bottom of the holster 19 that can be detachably connected to at least two types of gun heads;

[0105] It also includes a piston rod 18 fixed to the output end of the linear drive assembly, and the piston rod 18 is inserted into the holster 19 and slidably connected thereto.

[0106] This embodiment designs a dedicated pipetting mechanism 100, the bottom of which can be detachably connected to at least two types of gun tips, so that the pipetting mechanism 100 of the present application can draw sample mother solution into the sample test tube when connected to one type of gun tip, and can draw sample reaction solution from the sample test tube after connecting to another type of gun tip, and before releasing the sample reaction solution into the sample bottle, the filter membrane is pressed onto the gun tip, thereby realizing the automated operation process of drawing, transferring, filtering and the like of two sample solutions by a single pipetting mechanism 100, thereby solving the problem that it is currently difficult for a single pipetting mechanism 100 to complete the automated operation of microbial solutions.

[0107] Specifically, in this embodiment, the bottom of the holster 19 is provided with a gun head mounting groove 191 whose size is smaller than the inner diameter of the gun head;

[0108] The gun head mounting groove 191 is sleeved and fixed with a first elastic ring protrusion 192 and a second elastic ring protrusion 193 . The first elastic ring protrusion 192 is located below the second elastic ring protrusion 193 , and the outer diameter of the second elastic ring protrusion 193 is greater than the outer diameter of the first elastic ring protrusion 192 .

[0109] By providing the first elastic ring protrusion 192 and the second elastic ring protrusion 193, the first elastic ring protrusion 192 and the second elastic ring protrusion 193 can respectively clamp two types of gun tips of different models to realize the extraction of sample mother liquid and sample reaction liquid. When the two gun tips need to be removed, the piston rod 18 is driven to move downward so that the piston head can directly push out the gun tip to remove the gun tip, thereby realizing automatic disassembly. In addition, since the sample reaction liquid after centrifugation needs to be filtered before being added to the sample bottle, after the sample reaction liquid is extracted, the entire gun sleeve 19 and the gun tip are directly driven to move downward to press the filter membrane onto the gun tip, and then transferred to the bottom of the sample bottle, the piston rod 18 is driven to move downward to complete the filtering operation in the process of releasing the sample reaction liquid.

[0110] The first elastic ring protrusion 192 and the second elastic ring protrusion 193 in the present embodiment are detachably mounted on the gun head mounting groove 191, so as to facilitate replacement of the first elastic ring protrusion 192 and the second elastic ring protrusion 193 during subsequent maintenance. The first elastic ring protrusion 192 and the second elastic ring protrusion 193 in the present embodiment are made of the same material, such as silicone, rubber or plastic.

[0111] Specifically, in this embodiment, the bottom of the holster 19 is further provided with a mounting cone 194 located below the gun head mounting groove 191;

[0112] The diameter size of the top of the installation cone 194 is smaller than the outer diameter size of the first elastic ring protrusion 192. By arranging the installation cone 194, a guiding effect can be played when the gun head is inserted into the bottom of the gun sleeve 19.

[0113] Specifically, in this embodiment, the linear drive assembly includes an inverted drive motor 11 and a pipetting screw 12 arranged on the output shaft of the drive motor 11;

[0114] It also includes a slider 16 vertically slidably connected to the mounting plate 13, and a threaded sleeve 15 fixed to the slider 16, and the threaded sleeve 15 is sleeved on the pipetting screw 12;

[0115] The top of the piston rod 18 is fixed on the slider 16. The driving motor 11 in this embodiment is a stepping motor. The driving motor 11 rotates to drive the pipetting screw 12 to rotate, and then the threaded sleeve 15 can be driven to drive the slider 16 to slide up and down, thereby driving the piston rod 18 to move up and down, and realize the actions of extracting liquid, releasing liquid, pushing off the gun head, etc., and the three-axis motion module can be used to drive the entire pipetting mechanism 100 to move up and down, so that the filter membrane can be pressed onto the gun head, so as to realize the filtering operation of the filter membrane when releasing the sample reaction liquid.

[0116] Specifically, in this embodiment, it also includes two bearings 14 respectively fixed to the top and bottom of the mounting plate 13, and a mounting block 17 disposed between the two bearings 14;

[0117] The mounting block 17 is located below the slider 16 , and a through hole for the pipetting screw 12 to pass through is provided on the mounting block 17 , and the holster 19 is fixed on the mounting block 17 ;

[0118] The output shaft of the driving motor 11 is arranged on the bearing 14 at the top, and a rotating shaft is fixed at the bottom of the pipetting screw 12, and the rotating shaft is rotatably connected to the bearing 14 at the bottom. The bearings 14 in this embodiment are all spherical bearings 14. By installing the bearings 14, the stability of the pipetting screw 12 during rotation can be improved. In this embodiment, the holster 19 is detachably fixed to the mounting block 17 by bolts, which is convenient for subsequent operation and maintenance.

[0119] It is to be understood that the above embodiments are merely exemplary embodiments used to illustrate the principles of the present invention, but the present invention is not limited thereto. For those skilled in the art, various modifications and improvements can be made without departing from the spirit and essence of the present invention, and these modifications and improvements are also considered to be within the scope of protection of the present invention.

Claims

1. A processing system for detecting microbial solutions, characterized in that: It comprises a frame and two sets of three-axis motion modules arranged on the frame, as well as at least one set of liquid transfer mechanism (100) and at least one set of capping mechanism (200), wherein the liquid transfer mechanism (100) and the capping mechanism (200) are respectively arranged at the output ends of the two sets of three-axis motion modules; It also includes a first placement area, a second placement area and a third placement area which are distributed in the transverse direction below the two sets of three-axis motion modules, and the first placement area, the second placement area and the third placement area are respectively provided with a first slide table (4), a second slide table (5) and a third slide table (6) which can slide in the longitudinal direction; It also includes a mother liquid test tube rack (41), a sample test tube rack (51) and a sample injection bottle rack (61) which are respectively placed on the first slide (4), the second slide (5) and the third slide (6); The capping mechanism (200) comprises an inverted capping motor (21), a connecting flange (23), and a capping cylinder (22) fixed to the capping motor (21) via the connecting flange (23); The capping motor (21) is a stepping motor or a servo motor; The capping cylinder (22) is a rotating finger cylinder; The capping mechanism (200) further comprises a vertical mounting plate (24) vertically arranged at the output end of the three-axis motion module, and the capping motor (21) is invertedly arranged on the output end of the three-axis motion module via the vertical mounting plate (24); The pipetting mechanism includes a mounting plate for vertically setting on the three-axis motion module, a linear drive assembly invertedly fixed on the mounting plate, and a gun holster for mounting a sampling gun head; The holster is arranged vertically, and a connection structure is provided at the bottom of the holster for detachable connection with at least two types of gun heads; It also includes a piston rod fixed to the output end of the linear drive assembly, the piston rod is inserted into the holster and slidably connected thereto; The first slide (4) is also provided with a gun tip storage rack (42) for storing gun tips of at least two specifications, and a waste gun storage box (43); The gun tip storage rack (42) and the waste gun storage box (43) are both located on a side of the first slide (4) away from the second slide (5); It also includes a tube cap storage rack (52) disposed on the second slide (5); The tube cap storage rack (52) is provided with a plurality of tube cap placement slots for placing the tube caps; The pipe cover placement groove is circular, and a pipe cover pushing hole with a diameter smaller than the pipe cover placement groove is provided at its bottom; It also includes a filter membrane storage rack (62) and a bottle cap storage rack (63) arranged on the third slide (6); A plurality of filter membrane placement slots and bottle cap placement slots are respectively provided on the filter membrane storage rack (62) and the bottle cap storage rack (63); The filter membrane placement slot and the bottle cap placement slot are both circular; A filter membrane pushing hole with a diameter smaller than that of the filter membrane placement groove is provided at the bottom of the filter membrane placement groove; A bottle cap pushing hole with a diameter smaller than the diameter of the bottle cap placing groove is arranged at the bottom of the bottle cap placing groove.

2. A processing system for detecting microbial solutions according to claim 1, characterized in that: It also includes at least two sets of storage rack discharging drives (72) respectively arranged on the second slide (5) and the third slide (6), and the storage rack discharging drive (72) includes a push rod arranged vertically and used to drive the discharge of materials in the tube cap placement slot, the filter membrane placement slot, and the bottle cap placement slot.

3. A processing system for detecting microbial solutions according to claim 1, characterized in that: It also includes a slide drive (71) for driving the first slide (4), the second slide (5), and the third slide (6) to move in the longitudinal direction; The slide drive (71) is a linear drive structure; The mother liquid test tube rack (41), the sample test tube rack (51) and the injection bottle rack (61) are all located at the front side of the first slide (4), the second slide (5) and the third slide (6) away from the slide drive (71).

4. A processing system for detecting a microbial solution according to claim 1, characterized in that: The third slide (6) is also provided with a filter membrane mounting frame (64), and the filter membrane mounting frame (64) is provided with a plurality of filter membrane placement points for individually placing filter membrane materials.

5. A processing system for detecting microbial solutions according to claim 1, characterized in that: Two sets of three-axis motion modules are distributed vertically up and down; The frame comprises two frame side plates (311) arranged in parallel, the three-axis operation module comprises two longitudinal guide rails (312) arranged on the frame side plates (311), and transverse guide rods (313) respectively arranged at two ends on the two longitudinal guide rails (312), the transverse guide rods (313) are provided with vertical guide rails, and the liquid transfer mechanism (100) and the capping mechanism (200) are arranged on the vertical guide rails.

6. A processing system for detecting microbial solutions according to claim 1, characterized in that: The mother liquid test tube rack (41), the sample test tube rack (51) and the injection bottle rack (61) are all components with locking structures.

Citation Information

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