Drug sample grinding device for drug testing
By using the lifting and lowering rotation and magnetic repulsion technology of the grinding pestle in the drug sample grinding device, combined with electromagnetic and electrostatic treatment, the problems of uneven grinding of automatic equipment and long time are solved, and efficient and uniform grinding of the drug and multiple operations are achieved.
Patent Information
- Application Number
- CN202411424007.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-12
- Publication Date
- 2024-12-24
- Estimated Expiration
- 2044-10-12
AI Technical Summary
The existing automatic equipment is fixed during the grinding of drugs and cannot adjust the particle size distribution of drugs, resulting in uneven grinding and long time.
A drug sample grinding device was designed, and the grinding pestle was used to squeeze and rotate the grinding module to perform extrusion and rotation grinding. The magnetic force of the magnetic circle block and the collision block were repulsed to achieve multiple vibration and redistribution of the drug, combining electromagnetic circles and buffering. The use of washer improves the grinding effect and reduces electrostatic adhesion through the grinding shell and conductive column.
It effectively improves the uniformity and efficiency of drug grinding, reduces grinding time, and reduces powder adhesion through electrostatic conduction, realizing multiple grinding operations of drugs.
Smart Images

Figure CN118925891B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to a medicine sample grinding device, in particular to a medicine sample grinding device used for medicine testing and applied in the field of medicine grinding technology. Background Art
[0002] During the production or research and development process, drug quality inspection is a crucial part, which is related to the safety of drug users. Drug inspection must be meticulous and accurate. During the drug inspection process, inspectors need to go through multiple steps, among which grinding the drug is a more important step. The drug grinding equipment determines the grinding quality of the drug.
[0003] The specification of Chinese invention patent CN202220540910.9 discloses "A drug grinding device for drug safety testing". Through the cooperation between the sliding sleeve and the limit member, when the drive motor rotates forward, the sliding sleeve will move downward, so that the grinding head can be extended into the grinding groove of the grinding member, so as to grind the medicine inside the grinding groove, which is convenient for later testing. After the grinding is completed, the drive motor is controlled to reverse, so that the grinding head can leave the grinding groove to take out the ground drug powder for testing.
[0004] Most of the existing drug grinding methods are manual grinding. Due to the uneven distribution of drug particles during the grinding process, experimenters will adjust their grinding direction and grinding angle to perform targeted grinding on areas with high particle size. However, when using automatic equipment to grind drugs, the movement of the grinding equipment is orderly and fixed, and it cannot be adjusted according to the distribution of drug particle size, which can easily cause problems such as uneven drug grinding and long drug grinding time. Summary of the invention
[0005] In view of the above-mentioned prior art, the technical problem to be solved by the present invention is that when the existing automatic equipment grinds the medicine, the movement of the grinding equipment is orderly and fixed, and cannot be adjusted according to the distribution of the medicine particle size, which easily causes the medicine to be ground unevenly and the medicine grinding time is long.
[0006] In order to solve the above problems, the present invention provides a drug sample grinding device for drug testing, comprising a base, a grinding cup is sleeved inside the base, a device cover is sleeved on the top of the grinding cup, the device cover is threadedly connected to the base, and a lifting and rotating module is fixedly connected to the top of the device cover, and a grinding pestle is fixedly connected to the output end of the lifting and rotating module, and the grinding pestle extends into the grinding cup;
[0007] The interior of the grinding pestle is hollow, and a vertical shaft is fixedly connected to the interior of the grinding pestle, a code-collision block is sleeved on the exterior of the vertical shaft, a spring is fixedly connected to the top of the code-collision block, a magnetic circle block is placed at the bottom of the base, both the magnetic circle block and the code-collision block are made of magnetic material, and the magnetic circle block and the code-collision block are arranged to repel each other magnetically.
[0008] In the drug sample grinding device for drug testing, the grinding pestle is inserted into the grinding cup to squeeze and rotate the drug in the grinding cup for grinding. The grinding pestle repeatedly moves up and down during the grinding process. The magnetic force between the magnetic circle block and the collision block is used to repel each other. When the grinding pestle rises and moves away from the magnetic circle block, the collision block descends and hits the grinding pestle, thereby shaking off the drug attached to the grinding pestle, thereby facilitating multiple grinding operations of the drug and effectively improving the drug grinding effect.
[0009] As a further improvement of the present application, a groove is fixedly connected to the middle part of the vertical axis, and an outer expansion ring is inserted into the inside of the groove. The outer expansion ring contacts the inner ring wall of the code-collision block. The outer expansion ring is used to resist the inner ring of the code-collision block, thereby realizing the force storage of the code-collision block and effectively improving the impact effect of the code-collision block.
[0010] As a further improvement of the present application, a slot is provided on the inner ring wall of the code collision block, which is clamped with the protruding end of the outer expansion ring. The outer expansion ring is made of spring steel material, and the outer ring of the outer expansion ring is clamped into the slot of the inner ring of the code collision block, thereby increasing the residence time of the code collision block at the outer expansion ring position and achieving the force storage effect of the code collision block.
[0011] As a further improvement of the present application, an electromagnetic coil is fixedly connected to the top of the vertical axis, and the electromagnetic coil vertically corresponds to the code-collision block. After the drug grinding is completed, the electromagnetic coil is energized to generate magnetic force, and the magnetic force repeatedly converts positive and negative, attracting the code-collision block to repeatedly collide with the grinding pestle, so as to facilitate the falling of the drug powder on the grinding pestle.
[0012] As another improvement of the present application, a buffer washer is fixedly connected to the bottom end of the electromagnetic coil, the buffer washer corresponds to the top end of the code-collision block, and the buffer washer is made of rubber material. The buffer washer is used to buffer the code-collision block that attracts the upward movement, thereby effectively protecting the code-collision block and the electromagnetic coil.
[0013] As another improved supplement of the present application, the bottom end of the grinding pestle is fixedly covered with a grinding shell. The grinding shell and the grinding cup are both hemispherical. The hemispherical grinding shell corresponds to the hemispherical grinding cup to grind the medicine, and at the same time it is convenient for large particles of medicine to roll to the middle of the grinding cup.
[0014] As another improved supplement of the present application, the grinding shell is made of agate material, and the lower surface of the grinding shell is frosted, the bottom end of the grinding cup is fixedly connected with a cup seat, and the grinding cup is made of stainless steel material, the cup seat is in adsorption contact with the magnetic circle block, and the grinding shell made of agate material and the grinding cup made of stainless steel material are frictionally ground to achieve static electricity generated by the grinding shell, thereby improving the attraction and attachment of the grinding pestle to the pharmaceutical powder, and the subsequent pharmaceutical powder is vibrated back into the grinding cup to achieve redistribution of the pharmaceutical powder in the grinding cup, which facilitates multiple grinding operations of the medicine, thereby effectively improving the pharmaceutical grinding effect.
[0015] As another improvement of the present application, a conductive column is inserted into the middle of the magnetic circle block, and the top of the conductive column is in contact with the middle of the cup seat. The conductive column is made of brass material. The conductive column conducts static electricity brought by the grinding cup, effectively reduces the static electricity brought by the grinding cup, and effectively reduces the adhesion of drug powder to the grinding cup, making it easier for the drug powder to be lifted up by the grinding pestle.
[0016] As another improvement supplement to the present application, a side plug plate is plugged into one end of the base, and the bottom end of the conductive column is fixedly connected to the side plug plate. By pulling out the side plug plate laterally, the conductive column drives the magnetic circle block to offset the cup seat of the grinding cup, thereby facilitating the removal of the grinding cup.
[0017] As another improvement supplement to the present application, the outside of the side plug plate is fixedly connected with a plug plate grip, and the end of the base away from the side plug plate is fixedly connected with a base grip. The plug plate grip and the base grip are horizontally corresponding to each other. Both hands apply force to the plug plate grip and the base grip respectively to facilitate the removal of the side plug plate.
[0018] In summary, during the grinding process of medicines, the medicine particles are placed in the grinding cup, the device cover is tightened on the top of the base, the grinding pestle is inserted into the grinding cup, and the lifting and rotating module drives the grinding pestle to lift and rotate, so that the grinding pestle crushes and grinds the medicines in the grinding cup. The grinding pestle repeatedly performs lifting and lowering movements during the grinding process, and the magnetic force between the magnetic ring block and the collision block is used to repel each other. When the grinding pestle moves downward, the collision block rises in the opposite direction. When the grinding pestle moves upward, the collision block descends and hits the grinding pestle, so that the medicines attached to the grinding pestle are shaken off, and the medicine powders are shaken back to the grinding cup for redistribution, which is convenient for multiple grinding operations of the medicines, effectively improving the uniformity of the medicine grinding effect, and effectively reducing the medicine grinding time. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 This is a three-dimensional structural diagram of the first embodiment of the present application;
[0020] Figure 2 It is a cross-sectional view of the first embodiment of the present application;
[0021] Figure 3 This is a bottom-up stereoscopic structural diagram of the first embodiment of the present application;
[0022] Figure 4 This is a three-dimensional structural diagram of a grinding pestle according to the first embodiment of the present application;
[0023] Figure 5 This is a cross-sectional view of a grinding pestle according to the first embodiment of the present application;
[0024] Figure 6 This is a demonstration diagram of the lifting movement of the code collision block in the first implementation mode of the present application;
[0025] Figure 7 This is a three-dimensional structural diagram of the outer expansion ring of the second embodiment of the present application;
[0026] Figure 8 This is a three-dimensional structural diagram of a grinding cup according to a second embodiment of the present application;
[0027] Fig. 9 This is a cross-sectional view of a grinding cup and a side insert plate according to a second embodiment of the present application;
[0028] Fig.10 This is a three-dimensional structural diagram of the side plug plate of the second embodiment of the present application.
[0029] Description of the numbers in the figure:
[0030] 1. Base; 101. Grinding cup; 102. Device cover; 103. Lifting and rotating module; 2. Grinding pestle; 201. Vertical axis; 202. Collision block; 203. Spring; 204. Magnetic circle block; 205. Groove; 206. Outer expansion ring; 207. Card slot; 208. Grinding shell; 209. Cup holder; 3. Electromagnetic coil; 301. Buffer gasket; 4. Conductive column; 401. Side plug-in plate; 402. Plug-in plate gripper; 403. Base gripper. DETAILED DESCRIPTION
[0031] Two implementation modes of the present application are described in detail below with reference to the accompanying drawings.
[0032] The first implementation method:
[0033] Figure 1-5The invention shows a drug sample grinding device for drug detection, comprising a base 1, a grinding cup 101 is sleeved inside the base 1, a device cover 102 is sleeved on the top of the grinding cup 101, the device cover 102 is threadedly connected to the base 1, and a lifting and rotating module 103 is fixedly connected to the top of the device cover 102, a grinding pestle 2 is fixedly connected to the output end of the lifting and rotating module 103, the grinding pestle 2 extends into the grinding cup 101, the grinding pestle 2 is hollow inside, and a vertical shaft 201 is fixedly connected inside the grinding pestle 2, a code collision block 202 is sleeved outside the vertical shaft 201, a spring 203 is fixedly connected to the top of the code collision block 202, a magnetic circle block 204 is placed at the bottom of the base 1, the magnetic circle block 204 and the code collision block 202 are both made of magnetic material, and the magnetic circle block 204 and the code collision block 202 are arranged to repel each other magnetically;
[0034] During the grinding process of the medicine, the medicine particles are placed in the grinding cup 101, and then the device cover 102 is tightened and covered, and the grinding pestle 2 is inserted into the grinding cup 101. The lifting and rotating module 103 drives the grinding pestle 2 to lift and rotate to crush and grind the medicine in the grinding cup 101. The grinding pestle 2 repeatedly performs lifting and lowering movements during the grinding process. When the grinding pestle 2 moves downward, the distance between the magnetic circle block 204 and the code collision block 202 is shortened, so that the code collision block 202 rises in the opposite direction. When the grinding pestle 2 moves upward, the distance between the magnetic circle block 204 and the code collision block 202 increases, and the code collision block 202 descends and hits the grinding pestle 2, so that the medicine attached to the grinding pestle 2 is shaken off, and the medicine powder is shaken back to the grinding cup 101 for redistribution, mainly so that the large particles of the medicine are in the middle of the grinding cup 101, which is convenient for multiple grinding operations of the medicine, effectively improves the uniformity of the medicine grinding effect, and effectively reduces the grinding time of the medicine.
[0035] Figure 5-7 As shown, a groove 205 is fixedly connected to the middle of the vertical shaft 201, and an outer expansion ring 206 is inserted into the interior of the groove 205. The outer expansion ring 206 contacts the inner ring wall of the code-colliding block 202, and the outer expansion ring 206 is used to resist the inner ring of the code-colliding block 202, so as to realize the force storage of the code-colliding block 202, and effectively improve the impact effect of the code-colliding block 202. A card slot 207 is provided on the inner ring wall of the code-colliding block 202, and the card slot 207 is carded with the protruding end of the outer expansion ring 206. The outer expansion ring 206 is made of spring steel material, and the outer ring of the outer expansion ring 206 is carded into the card slot 207 of the inner ring of the code-colliding block 202, so as to increase the residence time of the code-colliding block 202 at the position of the outer expansion ring 206, and achieve the force storage effect of the code-colliding block 202;
[0036] During the lifting and lowering movement of the code-colliding block 202, the outer expansion circle 206 contacts the inner circle of the code-colliding block 202 and is stuck in the slot 207, so that the code-colliding block 202 stays at the position of the outer expansion circle 206 for a short time. Specifically, when the grinding pestle 2 rises and moves away from the grinding cup 101, when the distance between the magnetic circle block 204 and the code-colliding block 202 reaches a critical point, the elastic force of the spring 203 is sufficient to push the code-colliding block 202 away from the outer expansion circle 206, thereby achieving the force storage effect of the code-colliding block 202, thereby effectively improving the impact effect of the code-colliding block 202.
[0037] Figure 4-5 As shown, the top of the vertical shaft 201 is fixedly connected with an electromagnetic coil 3, and the electromagnetic coil 3 corresponds vertically to the code-colliding block 202. After the medicine grinding is completed, the electromagnetic coil 3 is energized to generate magnetic force, and the magnetic force repeatedly performs positive and negative conversion, attracting the code-colliding block 202 to repeatedly hit the grinding pestle 2, so as to facilitate the falling of the medicine powder on the grinding pestle 2. The bottom end of the electromagnetic coil 3 is fixedly connected with a buffer washer 301, and the buffer washer 301 corresponds to the top of the code-colliding block 202, and the buffer washer 301 is made of rubber material. The buffer washer 301 is used to buffer the code-colliding block 202 that attracts the upward movement, so as to effectively protect the code-colliding block 202 and the electromagnetic coil 3;
[0038] After the tablet grinding is completed, the electromagnetic coil 3 is energized to generate magnetic force. The electromagnetic coil 3 generates a magnetic force that attracts the code-collision block 202, attracting the code-collision block 202 to move upward. Conversely, the electromagnetic coil 3 generates a magnetic force that repels the code-collision block 202, pushing the code-collision block 202 to move downward, so that the code-collision block 202 repeatedly hits the grinding pestle 2, which facilitates the falling of the medicine powder on the grinding pestle 2. The buffer washer 301 buffers the code-collision block 202 that is attracted to move upward, and effectively protects the code-collision block 202 and the electromagnetic coil 3.
[0039] The second implementation method:
[0040] Compared with the first embodiment, this embodiment mainly adds a grinding shell 208 and a conductive column 4. The specific newly added structure is as follows, and the remaining structure is consistent with the first embodiment.
[0041] Figure 3-5 and Figure 8-9As shown, the bottom end of the grinding pestle 2 is fixedly covered with a grinding shell 208, and the grinding shell 208 and the grinding cup 101 are both hemispherical. The hemispherical grinding shell 208 corresponds to the hemispherical grinding cup 101 to grind the medicine, and at the same time, it is convenient for large particles of medicine to roll down to the middle of the grinding cup 101. The grinding shell 208 is made of agate material, and the lower surface of the grinding shell 208 is frosted. The bottom end of the grinding cup 101 is fixedly connected with a cup seat 209, and the grinding cup 101 is made of stainless steel material. The cup seat 209 The grinding shell 208 made of agate material is in contact with the magnetic ring block 204, so as to facilitate the adsorption and fixation of the grinding cup 101, and effectively improve the stability of the grinding cup 101. The grinding shell 208 made of agate material and the grinding cup 101 made of stainless steel material are rubbed and ground, so that the grinding shell 208 generates static electricity, thereby improving the attraction and attachment of the grinding pestle 2 to the drug powder. The subsequent drug powder is shaken back to the grinding cup 101, so that the drug powder is redistributed in the grinding cup 101, which is convenient for multiple grinding operations of the drug, thereby effectively improving the drug grinding effect;
[0042] The hemispherical grinding shell 208 corresponds to the hemispherical grinding cup 101 for grinding medicines, which is convenient for fully grinding the medicines. At the same time, large particles of medicines can be easily rolled into the grinding cup 101, which effectively improves the grinding effect of the medicines. The grinding shell 208 made of agate material and the grinding cup 101 made of stainless steel material are rubbed and ground. The grinding shell 208 generates static electricity to attract the medicine powder, which makes it convenient for the grinding pestle 2 to attach more medicine powder and rise. The subsequent medicine powder is vibrated back to the grinding cup 101, which effectively improves the redistribution effect of the medicine powder in the grinding cup 101, thereby effectively improving the medicine grinding effect.
[0043] Figure 8-10 As shown, a conductive column 4 is inserted in the middle of the magnetic circle block 204, and the top of the conductive column 4 contacts the middle of the cup seat 209. The conductive column 4 is made of brass material. The conductive column 4 conducts the static electricity of the grinding cup 101, effectively reduces the static electricity of the grinding cup 101, and effectively reduces the adhesion of the drug powder to the grinding cup 101, so that the drug powder is convenient to be lifted by the grinding pestle 2. A side plug-in plate 401 is inserted at one end of the base 1, and the bottom end of the conductive column 4 is fixedly connected to the side plug-in plate 401. By The plug plate 401 is pulled out horizontally, so that the conductive column 4 drives the magnetic circle block 204 to stagger the cup seat 209 of the grinding cup 101, which is convenient for taking out the grinding cup 101. The outside of the side plug plate 401 is fixedly connected with a plug plate gripper 402, and the end of the base 1 away from the side plug plate 401 is fixedly connected with a base gripper 403. The plug plate gripper 402 corresponds to the base gripper 403 horizontally. Both hands apply force to the plug plate gripper 402 and the base gripper 403 respectively, which is convenient for pulling out the side plug plate 401.
[0044] The conductive column 4 is in contact with the cup seat 209 to conduct the static electricity of the grinding cup 101, effectively reducing the static electricity of the grinding cup 101, making it easier for the drug powder to be conducted away from the static electricity of the grinding cup 101, effectively reducing the static electricity of the grinding cup 101, and effectively reducing the adsorption and lifting of the drug powder adhering to the grinding cup 101. After the drug grinding is completed, the experimenter applies force to the plug plate gripper 402 and the base gripper 403 with both hands respectively to facilitate the removal of the side plug plate 401, driving the magnetic circle block 204 to offset the cup seat 209 of the grinding cup 101, thereby facilitating the removal of the grinding cup 101.
[0045] In view of current practical needs, the above-mentioned implementation mode adopted in this application is not limited to the scope of protection. Various changes made within the knowledge scope of technical personnel in this field without departing from the concept of this application still fall within the scope of protection of the present invention.
Claims
1. A drug sample grinding device for drug testing, characterized in that: The invention comprises a base (1), wherein a grinding cup (101) is sleeved inside the base (1), a device cover (102) is sleeved on the top of the grinding cup (101), the device cover (102) is threadedly connected to the base (1), and a lifting and rotating module (103) is fixedly connected to the top of the device cover (102), and a grinding pestle (2) is fixedly connected to the output end of the lifting and rotating module (103), and the grinding pestle (2) extends into the grinding cup (101); The grinding pestle (2) is hollow inside, and a vertical shaft (201) is fixedly connected inside the grinding pestle (2), a code collision block (202) is sleeved outside the vertical shaft (201), a spring (203) is fixedly connected to the top of the code collision block (202), and a magnetic ring block (204) is placed at the bottom of the base (1), the magnetic ring block (204) and the code collision block (202) are both made of magnetic material, and the magnetic ring block (204) and the code collision block (202) are magnetically repelled from each other. The bottom end of the grinding pestle (2) is fixedly covered with a grinding shell (208), the grinding shell (208) and the grinding cup (101) are both hemispherical, the grinding shell (208) is made of agate material, and the lower surface of the grinding shell (208) is frosted, the bottom end of the grinding cup (101) is fixedly connected with a cup seat (209), and the grinding cup (101) is made of stainless steel material, and the cup seat (209) is in adsorption contact with the magnetic ring block (204); A groove (205) is fixedly connected to the middle of the vertical shaft (201), an outer expansion ring (206) is inserted into the interior of the groove (205), the outer expansion ring (206) contacts the inner ring wall of the code collision block (202), the inner ring wall of the code collision block (202) is provided with a clamping groove (207), the clamping groove (207) is clamped with the protruding end of the outer expansion ring (206), the outer expansion ring (206) is made of spring steel material, the top of the vertical shaft (201) is fixedly connected to an electromagnetic ring (3), the electromagnetic ring (3) vertically corresponds to the code collision block (202), the bottom end of the electromagnetic ring (3) is fixedly connected to a buffer washer (301), the buffer washer (301) corresponds to the top of the code collision block (202), and the buffer washer (301) is made of rubber material; The drug particles are placed in a grinding cup (101), the top of the base (1) is screwed on with a device cover (102), the grinding pestle (2) is inserted into the grinding cup (101), and the lifting and rotating module (103) drives the grinding pestle (2) to lift and rotate, so that the grinding pestle (2) crushes and grinds the drug in the grinding cup (101). The grinding pestle (2) repeatedly lifts and lowers during the grinding process, and the magnetic force between the magnetic ring block (204) and the collision block (202) is used to repel each other. When the grinding pestle (2) moves downward, the collision block (202) rises in the opposite direction. When the grinding pestle (2) moves upward, the collision block (202) falls and hits the grinding pestle (2), so that the drug attached to the grinding pestle (2) is shaken off, and the drug powder is shaken back to the grinding cup (101) for redistribution, so as to facilitate multiple grinding operations of the drug.
2. A drug sample grinding device for drug testing according to claim 1, characterized in that: A conductive column (4) is inserted into the middle of the magnetic ring block (204), the top of the conductive column (4) is in contact with the middle of the cup seat (209), and the conductive column (4) is made of brass material.
3. A drug sample grinding device for drug testing according to claim 2, characterized in that: One end of the base (1) is plugged with a side plug plate (401), and the bottom end of the conductive column (4) is fixedly connected to the side plug plate (401).
4. A drug sample grinding device for drug testing according to claim 3, characterized in that: The outside of the side plug plate (401) is fixedly connected with a plug plate gripper (402), and one end of the base (1) away from the side plug plate (401) is fixedly connected with a base gripper (403), and the plug plate gripper (402) corresponds horizontally to the base gripper (403).
Citation Information
Patent Citations
Medicine grinding device for medicine safety detection
CN217888089U
Moxa repeated sieving and pestling device for asshion manufacturing
CN108579868A
High-efficiency raw material grinding device for biological pharmacy
CN112495548A
Cited By
Grinding device for medicine detection
CN119972308A
