A multi-modality imaging system and coronary angiography catheter

Abstract

The application provides a multi-modal imaging system and a coronary angiography catheter, which obtains the coronary artery structure after the coronary angiography catheter enters the coronary artery of a patient and injects contrast medium, determines an imaging area based on the coronary artery structure, provides a basis for multi-modal imaging, then performs optical scanning on the imaging area to obtain an optical coherence tomography image, performs fluorescence detection on the imaging area to obtain a fluorescence imaging image, obtains image types in multiple modes, provides a multi-modal image basis for providing comprehensive and accurate medical images, integrates the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image to realize accurate determination of the position and type of coronary blood, and obtains a multi-modal imaging image; the multi-modal imaging system combines multiple imaging modes to provide more comprehensive and accurate medical images, so that doctors can simultaneously obtain multiple types of medical image information.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical imaging equipment, in particular to a multi-modal imaging system and a coronary angiography catheter. BACKGROUND

[0002] In diagnosis and treatment, coronary angiography technology is an important examination method for current cardiovascular diseases. Through coronary angiography technology, a physician can understand the degree of coronary stenosis of a patient in a short time, and make a certain judgment based on this to decide whether to perform stent implantation.

[0003] The coronary angiography catheter can accurately enter the coronary artery of a patient, and clearly display the anatomical structure and lesion of the coronary artery by injecting contrast agent. For the determination of the degree of coronary stenosis of a patient, further imaging analysis is needed. Currently, a doctor usually determines the position and type of a coronary blood vessel according to an optical coherence tomography module. Single image determination results in an image result that is not accurate and comprehensive enough, leading to subjective diagnosis results and causing certain difficulties for subsequent treatment work. SUMMARY

[0004] The present application provides a multi-modal imaging system and a coronary angiography catheter to solve the problems raised in the background art.

[0005] A multi-modal imaging system comprises:

[0006] An imaging area determination module is configured to obtain a coronary artery structure after a coronary angiography catheter enters a coronary artery of a patient and injects contrast agent, and determine an imaging area based on the coronary artery structure;

[0007] An optical coherence tomography module is configured to perform optical scanning on the imaging area to obtain an optical coherence tomography image;

[0008] An ultrasound imaging module is configured to perform ultrasound scanning on the imaging area to obtain an ultrasound imaging image;

[0009] A fluorescence imaging module is configured to perform fluorescence detection on the imaging area to obtain a fluorescence imaging image;

[0010] An integration module is configured to integrate the optical coherence tomography image, the ultrasound imaging image, and the fluorescence imaging image to obtain a multi-modal imaging image.

[0011] Preferably, the imaging area determination module comprises:

[0012] A general imaging unit is configured to perform general imaging on the coronary artery structure after the coronary angiography catheter enters the coronary artery of the patient and injects the contrast agent to obtain a coronary artery basic image;

[0013] The difference determination unit is configured to compare the coronary artery base image with the standard base image to obtain an image difference;

[0014] The region determination unit is configured to obtain a position region of the image difference on the coronary artery base image, and expand the position region based on a region size and a region feature of the position region to obtain a target region, and take the target region as an imaging region.

[0015] Preferably, the optical coherence tomography module comprises:

[0016] The marking unit is configured to dynamically mark the imaging region based on the region lesion feature to obtain a dynamic marking sequence, and determine a scanning tracking sequence based on the dynamic marking sequence.

[0017] The scanning unit is configured to determine an optical scanning parameter according to the scanning tracking sequence, and perform optical scanning on the imaging region according to the optical scanning parameter to obtain a scanning data set.

[0018] The image generation unit is configured to perform dispersion correction on the scanning data set to obtain a target data set, and generate an optical coherence tomography image based on the target data set.

[0019] Preferably, the marking unit comprises:

[0020] The marking determination unit is configured to perform transverse analysis on the region lesion feature, and perform lesion level marking on the imaging region according to a lesion degree.

[0021] The marking sequence generation unit is configured to perform longitudinal analysis on the region lesion feature based on the lesion level marking, determine a position dynamic feature of the lesion level marking, dynamically mark the imaging region based on the position dynamic feature, and obtain a dynamic marking sequence.

[0022] The tracking sequence generation unit is configured to determine a scanning region importance level based on the lesion level marking in the dynamic marking sequence, determine a scanning region dynamic feature based on the position dynamic feature in the dynamic marking sequence, and generate a scanning tracking sequence based on the scanning region importance level and the scanning region dynamic feature.

[0023] Preferably, the ultrasound imaging module comprises:

[0024] The orientation determination unit is configured to obtain orientation information of the imaging region by using an orientation sensor.

[0025] The ultrasound imaging unit is configured to determine an ultrasound scanning parameter based on the orientation information, and perform ultrasound scanning on the imaging region by using the ultrasound scanning parameter to obtain an ultrasound imaging image.

[0026] Preferably, the fluorescence imaging module comprises:

[0027] a segmentation unit configured to perform fluorescence detection on the imaging region to obtain a real-time fluorescence image, determine a fluorescence spectral wavelength of the real-time fluorescence image, and segment the real-time fluorescence image based on the fluorescence spectral wavelength to obtain a fluorescence region image in which main information exists;

[0028] a fusion unit configured to perform saliency detection on the fluorescence region image and fuse the fluorescence region image with a visible light image of the imaging region to obtain a fluorescence imaging image.

[0029] Preferably, the fusion unit comprises:

[0030] a detection unit configured to perform saliency detection on the fluorescence region image by using a saliency detection algorithm to obtain a saliency fluorescence image, and perform saliency detection on the visible light image by using the saliency detection algorithm to obtain a saliency visible light image;

[0031] an image fusion unit configured to fuse the saliency fluorescence image and the saliency visible light image based on an image fusion technique to obtain the fluorescence imaging image.

[0032] Preferably, the integration module comprises:

[0033] a positioning unit configured to mark a key position of the imaging region to obtain a position marker, acquire a first position feature, a second position feature and a third position feature of the position marker in an optical coherence tomography image, an ultrasound imaging image and the fluorescence imaging image respectively, and perform synchronous positioning on the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image based on the first position feature, the second position feature and the third position feature to obtain positioning information;

[0034] a fusion unit configured to fuse the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image based on the positioning information to obtain a fused imaging image;

[0035] a difference comparison unit configured to compare the fused imaging image with main image features of the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image respectively to obtain image feature differences, and determine whether the image feature differences are within a preset difference range;

[0036] If yes, it is determined that no multi-type conflict exists in the fused imaging image, and the fused imaging image is taken as an initial multi-modal imaging;

[0037] Otherwise, it is determined that a multi-type conflict exists in the fused imaging image, and the fused imaging image is corrected based on the image feature differences and in combination with the main image features to obtain an initial multi-modal imaging image;

[0038] The processing unit is configured to perform background weakening and lesion area proportion increasing processing on the initial multi-modal imaging image to obtain a final multi-modal imaging image.

[0039] Preferably, the difference comparison unit comprises:

[0040] The weight determination unit is configured to determine a first correction weight based on the difference size of the image feature difference, and determine a second correction weight based on the contribution degree of the main image feature to the lesion diagnosis.

[0041] The correction unit is configured to determine a correction scheme based on the main image feature, determine a specific correction value in the correction scheme based on the first correction weight and the second correction weight, correct the fused imaging image according to the specific correction value, and obtain the initial multi-modal imaging image.

[0042] Preferably, a coronary angiography catheter comprises: the coronary angiography catheter is composed of a head end, a catheter and a catheter seat, the material of the head end is polyamide, and the material of the catheter is polyamide.

[0043] Compared with the prior art, the present application has the following beneficial effects:

[0044] 1) By acquiring the coronary artery structure after the coronary angiography catheter enters the coronary artery of the patient and injects the contrast agent, determining the imaging area based on the coronary artery structure, providing a basis for multi-modal imaging, then performing optical scanning on the imaging area to obtain an optical coherence tomography image, performing fluorescence detection on the imaging area to obtain a fluorescence imaging image, obtaining image types in multiple modes, providing a multi-modal image basis for providing comprehensive and accurate medical images, and integrating the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image to realize accurate determination of the coronary blood position and type, obtain a multi-modal imaging image, and combine the multi-modal imaging system with multiple imaging modes to provide more comprehensive and accurate medical images, so that doctors can obtain multiple types of medical image information at the same time.

[0045] 2) By marking the key positions of the imaging area, position marking points are obtained, the first position feature, the second position feature and the third position feature of the position marking points in the optical coherence tomography image, the ultrasound image and the fluorescence image are respectively acquired, and the optical coherence tomography image, the ultrasound image and the fluorescence image are synchronously positioned based on the first position feature, the second position feature and the third position feature, positioning information is obtained, the optical coherence tomography image, the ultrasound image and the fluorescence image are uniformly positioned, a position basis is provided for image integration, then the optical coherence tomography image, the ultrasound image and the fluorescence image are fused based on the positioning information, a fused imaging image is obtained, the fusion of multi-modal images is realized, the viewing of multi-modal images is more convenient and accurate, secondly, the main image features of the fused imaging image, the optical coherence tomography image, the ultrasound image and the fluorescence image are compared, image feature differences are obtained, and it is judged whether the image feature differences are within a preset difference range, if yes, it is determined that there is no multi-type conflict in the fused imaging image, and the fused imaging image is taken as the initial multi-modal imaging; otherwise, it is determined that there is multi-type conflict in the fused imaging image, and the fused imaging image is corrected based on the image feature differences and in combination with the main image features, an initial multi-modal imaging image is obtained, the image accuracy of each modality of the initial multi-modal imaging image is ensured, finally, the initial multi-modal imaging image is processed by background weakening and lesion area proportion increasing, a final multi-modal imaging image is obtained, the accurate determination of coronary blood position and type is realized, the multi-modal imaging image is obtained, the multi-modal imaging system combines multiple imaging modalities, provides more comprehensive and accurate medical images, and enables doctors to simultaneously obtain multiple types of medical image information.

[0046] Additional features and advantages of the application will be set forth in the description that follows, and in part will be apparent from the description, or can be learned by practice of the application. The objectives and other advantages of the application will be realized and attained by the structure particularly pointed out in the written description and claims thereof.

[0047] The technical solutions of the present application are described in detail below with the aid of the accompanying drawings and examples. BRIEF DESCRIPTION OF DRAWINGS

[0048] The accompanying drawings are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and serve to explain the principles of the application, and do not limit the application. In the drawings:

[0049] Figure 1 It is a structure diagram of a multi-modal imaging system in an embodiment of the present application;

[0050] Figure 2 It is a structure diagram of the imaging area determination module in the embodiment of the present application;

[0051] Figure 3 FIG. 4 is a structural diagram of the optical coherence tomography module according to an embodiment of the present invention. DETAILED DESCRIPTION

[0052] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0053] Example 1:

[0054] The present invention provides a multimodal imaging system. Figure 1 As shown, including:

[0055] An imaging region determination module is used to obtain the coronary artery structure after the coronary angiography catheter enters the patient's coronary artery and injects contrast agent, and to determine the imaging region based on the coronary artery structure;

[0056] An optical coherence tomography module, used for optically scanning an imaging area to obtain an optical coherence tomography image;

[0057] An ultrasonic imaging module, configured to perform ultrasonic scanning on an imaging area to obtain an ultrasonic imaging image;

[0058] A fluorescence imaging module is used to perform fluorescence detection on the imaging area to obtain a fluorescence imaging image;

[0059] The integration module is used to integrate the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image to obtain a multimodal imaging image.

[0060] In this embodiment, the imaging region is determined based on the coronary artery structure according to common imaging results, such as grayscale images.

[0061] In this embodiment, the integration of the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image includes operations such as image positioning, fusion and correction.

[0062] The beneficial effects of the above design scheme are: by acquiring the coronary artery structure after the coronary angiography catheter enters the coronary artery of the patient and injects the contrast agent, the imaging area is determined based on the coronary artery structure, and a basis is provided for multi-modal imaging, then, the imaging area is optically scanned to obtain an optical coherence tomography image, the imaging area is subjected to fluorescence detection to obtain a fluorescence imaging image, and images of multiple modes are obtained, thereby providing a multi-modal image basis for providing comprehensive and accurate medical images, by integrating the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image, accurate determination of the coronary blood position and type is realized, and a multi-modal imaging image is obtained, the multi-modal imaging system combines multiple imaging modes to provide more comprehensive and accurate medical images, so that the doctor can obtain multiple types of medical image information at the same time.

[0063] Embodiment 2

[0064] Based on the basis of embodiment 1, the embodiment of the application provides a multi-modal imaging system, as shown in Figure 2 The imaging area determination module comprises:

[0065] The common imaging unit is configured to perform common imaging on the coronary artery structure after the coronary angiography catheter enters the coronary artery of the patient and injects the contrast agent, and obtain a coronary artery basic image.

[0066] The difference determination unit is configured to compare the coronary artery basic image with a standard basic image to obtain an image difference.

[0067] The region determination unit is configured to acquire a position region of the image difference on the coronary artery basic image, and expand the position region based on a region size and a region feature of the position region to obtain a target region, and take the target region as the imaging area.

[0068] The beneficial effects of the above design scheme are: by acquiring the coronary artery structure after the coronary angiography catheter enters the coronary artery of the patient and injects the contrast agent, the imaging area is determined based on the coronary artery structure, and a basis is provided for multi-modal imaging, then, the imaging area is optically scanned to obtain an optical coherence tomography image, the imaging area is subjected to fluorescence detection to obtain a fluorescence imaging image, and images of multiple modes are obtained, thereby providing a multi-modal image basis for providing comprehensive and accurate medical images, by integrating the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image, accurate determination of the coronary blood position and type is realized, and a multi-modal imaging image is obtained, the multi-modal imaging system combines multiple imaging modes to provide more comprehensive and accurate medical images, so that the doctor can obtain multiple types of medical image information at the same time.

[0069] Embodiment 3

[0070] Based on the basis of embodiment 1, the embodiment of the application provides a multi-modal imaging system, as shown in Figure 3 The optical coherence tomography imaging module comprises:

[0071] a marking unit, configured to mark the imaging region dynamically based on the regional lesion feature to obtain a dynamic marking sequence, and determine a scanning tracking sequence based on the dynamic marking sequence;

[0072] a scanning unit, configured to determine an optical scanning parameter according to the scanning tracking sequence, and perform optical scanning on the imaging region according to the optical scanning parameter to obtain a scanning data set;

[0073] an image generation unit, configured to perform dispersion correction on the scanning data set to obtain a target data set, and generate an optical coherence tomography image based on the target data set.

[0074] The above design scheme has the beneficial effects that: the imaging region is marked dynamically based on the regional lesion feature to obtain a dynamic marking sequence, and a scanning tracking sequence is determined based on the dynamic marking sequence, an optical scanning parameter is determined according to the scanning tracking sequence, the imaging region is optically scanned according to the optical scanning parameter to obtain a scanning data set, dispersion correction is performed on the scanning data set to obtain a target data set, and an optical coherence tomography image is generated based on the target data set, thereby providing an optical coherence tomography image type for multi-modal imaging.

[0075] Embodiment 4:

[0076] Based on the basis of embodiment 3, the embodiment of the application provides a multi-modal imaging system, and the marking unit comprises:

[0077] a marking determination unit, configured to perform transverse analysis on the regional lesion feature, and perform lesion level marking on the imaging region according to the lesion degree;

[0078] a marking sequence generation unit, configured to perform longitudinal analysis on the regional lesion feature based on the lesion level marking, determine position dynamic features of the lesion level marking, mark the imaging region dynamically based on the position dynamic features, and obtain a dynamic marking sequence;

[0079] a tracking sequence generation unit, configured to determine a scanning region key level based on the lesion level marking in the dynamic marking sequence, determine a scanning region dynamic feature based on the position dynamic features in the dynamic marking sequence, and generate a scanning tracking sequence based on the scanning region key level and the scanning region dynamic feature.

[0080] In this embodiment, the transverse analysis on the regional lesion feature is analysis on the same image, and the longitudinal analysis on the regional lesion feature is analysis on multiple images obtained in multiple time periods.

[0081] The beneficial effects of the above design scheme are: through the transverse analysis on the regional lesion characteristics, the lesion level markers are marked on the imaging region according to the lesion degree, the lesion level characteristics on the same image are determined, the scanning region key level in the scanning tracking sequence is determined, through the lesion level markers, the longitudinal analysis on the regional lesion characteristics is performed, the position dynamic characteristics of the lesion level markers are determined, the imaging region is dynamically marked based on the position dynamic characteristics, the dynamic marking sequence is obtained, the scanning region dynamic characteristics in the scanning tracking sequence are determined, finally, the scanning region key level is determined based on the lesion level markers in the dynamic marking sequence, the scanning region dynamic characteristics are determined based on the position dynamic characteristics in the dynamic marking sequence, and the scanning tracking sequence is generated based on the scanning region key level and the scanning region dynamic characteristics, thereby providing a basis for generating an accurate optical coherence tomography image.

[0082] Embodiment 5

[0083] Based on the basis of embodiment 1, the embodiment of the application provides a multi-modal imaging system, and the ultrasound imaging module comprises:

[0084] The azimuth determination unit is configured to acquire azimuth information of the imaging region by using an azimuth sensor.

[0085] The ultrasound imaging unit is configured to determine ultrasound scanning parameters based on the azimuth information, and perform ultrasound scanning on the imaging region by using the ultrasound scanning parameters to obtain an ultrasound imaging image.

[0086] The beneficial effects of the above design scheme are: by acquiring the azimuth information of the imaging region by using the azimuth sensor, determining the ultrasound scanning parameters based on the azimuth information, and performing the ultrasound scanning on the imaging region by using the ultrasound scanning parameters to obtain the ultrasound imaging image, the ultrasound imaging image type is provided for the multi-modal imaging.

[0087] Embodiment 6

[0088] Based on the basis of embodiment 1, the embodiment of the application provides a multi-modal imaging system, and the fluorescence imaging module comprises:

[0089] The segmentation unit is configured to perform fluorescence detection on the imaging region to obtain a real-time fluorescence image, determine a fluorescence spectral wavelength of the real-time fluorescence image, and perform segmentation on the real-time fluorescence image based on the fluorescence spectral wavelength to obtain a fluorescence region image in which main information exists.

[0090] The fusion unit is configured to perform saliency detection on the fluorescence region image, and fuse the fluorescence region image with a visible light image of the imaging region to obtain a fluorescence imaging image.

[0091] The beneficial effects of the above design scheme are: through fluorescence detection on the imaging area, a real-time fluorescence image is obtained, the fluorescence spectrum wavelength of the real-time fluorescence image is determined, the real-time fluorescence image is segmented based on the fluorescence spectrum wavelength, a fluorescence region image with main information is obtained, saliency detection is performed on the fluorescence region image, and the fluorescence region image is fused with a visible light image of the imaging area to obtain a fluorescence imaging image, thereby providing a fluorescence imaging image type for multi-modal imaging.

[0092] Embodiment 7:

[0093] Based on the basis of embodiment 6, the embodiment of the application provides a multi-modal imaging system, and the fusion unit comprises:

[0094] The detection unit is configured to perform saliency detection on the fluorescence region image by using a saliency detection algorithm to obtain a saliency fluorescence image, and perform saliency detection on the visible light image by using the saliency detection algorithm to obtain a saliency visible light image.

[0095] The image fusion unit is configured to fuse the saliency fluorescence image and the saliency visible light image based on an image fusion technology to obtain the fluorescence imaging image.

[0096] In this embodiment, the saliency detection algorithm is adaptively selected from existing saliency detection algorithms, and the image fusion technology is adaptively selected from existing image fusion technologies.

[0097] The beneficial effects of the above design scheme are: through saliency detection on the fluorescence region image by using a saliency detection algorithm to obtain a saliency fluorescence image, saliency detection on the visible light image by using the saliency detection algorithm to obtain a saliency visible light image, and fusion of the saliency fluorescence image and the saliency visible light image based on an image fusion technology to obtain the fluorescence imaging image, the accuracy of the obtained fluorescence imaging image is ensured, and high-quality image basis is provided for final multi-modal imaging.

[0098] Embodiment 8:

[0099] Based on the basis of embodiment 1, the embodiment of the application provides a multi-modal imaging system, and the integration module comprises:

[0100] The positioning unit is configured to mark a key position of the imaging area to obtain a position marking point, acquire a first position feature, a second position feature and a third position feature of the position marking point in the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image respectively, and perform synchronous positioning on the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image based on the first position feature, the second position feature and the third position feature to obtain positioning information.

[0101] a fusion unit configured to fuse the optical coherence tomography image, the ultrasound image and the fluorescence image based on the positioning information to obtain a fused imaging image;

[0102] a difference comparison unit configured to compare the fused imaging image with main image features of the optical coherence tomography image, the ultrasound image and the fluorescence image respectively to obtain image feature differences, and determine whether the image feature differences are within a preset difference range;

[0103] if yes, it is determined that there is no multi-type conflict in the fused imaging image, and the fused imaging image is taken as an initial multi-modal imaging;

[0104] otherwise, it is determined that there is a multi-type conflict in the fused imaging image, and the fused imaging image is corrected based on the image feature differences and in combination with the main image features to obtain an initial multi-modal imaging image;

[0105] a processing unit configured to perform background weakening and lesion area proportion increasing processing on the initial multi-modal imaging image to obtain a final multi-modal imaging image.

[0106] The beneficial effects of the above design scheme are: by marking the key positions of the imaging area to obtain position marking points, the first position feature, the second position feature and the third position feature of the position marking points in the optical coherence tomography image, the ultrasound image and the fluorescence image are obtained respectively, and the optical coherence tomography image, the ultrasound image and the fluorescence image are positioned synchronously based on the first position feature, the second position feature and the third position feature to obtain positioning information, realizing the unified positioning of the optical coherence tomography image, the ultrasound image and the fluorescence image, providing a position basis for image integration, and then fusing the optical coherence tomography image, the ultrasound image and the fluorescence image based on the positioning information to obtain a fused imaging image, realizing the fusion of multi-modal images, making the viewing of multi-modal images more convenient and accurate, and secondly, comparing the fused imaging image with main image features of the optical coherence tomography image, the ultrasound image and the fluorescence image respectively to obtain image feature differences, and judging whether the image feature differences are within a preset difference range, if yes, determining that there is no multi-type conflict in the fused imaging image, and taking the fused imaging image as an initial multi-modal imaging; otherwise, it is determined that there is a multi-type conflict in the fused imaging image, and based on the image feature differences, the main image features are combined to correct the fused imaging image to obtain an initial multi-modal imaging image, ensuring the image accuracy of each modality of the initial multi-modal imaging image, and finally, the background of the initial multi-modal imaging image is weakened and the proportion of the lesion area is increased to obtain a final multi-modal imaging image, realizing accurate determination of coronary blood position and type, obtaining a multi-modal imaging image, and a multi-modal imaging system combines multiple imaging modalities to provide more comprehensive and accurate medical images, so that doctors can obtain multiple types of medical image information at the same time.

[0107] Embodiment 9:

[0108] Based on the basis of Embodiment 8, the present embodiment provides a multi-modal imaging system, the difference comparison unit comprises:

[0109] The weight determination unit is configured to determine a first correction weight based on the difference size of the image feature difference, and determine a second correction weight based on the contribution degree of the main image feature to the lesion diagnosis.

[0110] The correction unit is configured to determine a correction scheme based on the main image feature, determine a specific correction value in the correction scheme based on the first correction weight and the second correction weight, correct the fused imaging image according to the specific correction value, and obtain an initial multi-modal imaging image.

[0111] The beneficial effects of the above design scheme are: the first correction weight is determined based on the difference size of the image feature difference, the second correction weight is determined based on the contribution degree of the main image feature to the diagnosis of the lesion, the correction scheme is determined based on the main image feature, and the specific correction value in the correction scheme is determined based on the first correction weight and the second correction weight, the fusion imaging image is corrected according to the specific correction value, and the initial multi-modal imaging image is obtained, so that the image accuracy of each mode of the initial multi-modal imaging image is ensured.

[0112] Embodiment 10:

[0113] Based on the basis of embodiment 1, the application provides a coronary angiography catheter, comprising: the coronary angiography catheter is composed of a head end, a catheter and a catheter seat, the material of the head end is polyamide, and the material of the catheter is polyamide.

[0114] The beneficial effects of the above design scheme are: by providing a coronary angiography catheter, a basis for multi-modal imaging system imaging is provided.

[0115] Obviously, those skilled in the art can make various modifications and variations to the present application without departing from the spirit and scope of the present application. Thus, if these modifications and variations of the present application belong to the scope of the present application and its equivalent technologies, the present application also intends to include these modifications and variations.

Claims

1. A multimodal imaging system, characterized in that: include: An imaging region determination module is used to obtain the coronary artery structure after the coronary angiography catheter enters the patient's coronary artery and injects contrast agent, and to determine the imaging region based on the coronary artery structure; An optical coherence tomography module, used for optically scanning an imaging area to obtain an optical coherence tomography image; An ultrasonic imaging module, configured to perform ultrasonic scanning on an imaging area to obtain an ultrasonic imaging image; A fluorescence imaging module is used to perform fluorescence detection on the imaging area to obtain a fluorescence imaging image; An integration module is used to integrate the optical coherence tomography image, the ultrasound imaging image and the fluorescence imaging image to obtain a multimodal imaging image, including: a positioning unit, configured to mark key positions of an imaging area to obtain position marking points, obtain first position features, second position features, and third position features of the position marking points in the optical coherence tomography image, the ultrasound image, and the fluorescence image, respectively, and synchronously position the optical coherence tomography image, the ultrasound image, and the fluorescence image based on the first position features, the second position features, and the third position features to obtain positioning information; a fusion unit, configured to fuse the optical coherence tomography image, the ultrasound image, and the fluorescence image based on the positioning information to obtain a fused imaging image; a difference comparison unit, configured to compare the main image features of the fused imaging image with the optical coherence tomography image, the ultrasound imaging image, and the fluorescence imaging image, respectively, to obtain image feature differences, and to determine whether the image feature differences are within a preset difference range; If so, determining that there is no multi-type conflict in the fused imaging image, and using the fused imaging image as the initial multi-modal imaging; Otherwise, it is determined that there are multiple types of conflicts in the fused imaging image, and based on the image feature differences and in combination with the main image features, the fused imaging image is corrected to obtain an initial multimodal imaging image; The processing unit is used to perform background weakening and lesion area ratio increasing processing on the initial multimodal imaging image to obtain a final multimodal imaging image.

2. A multimodal imaging system according to claim 1, characterized in that: The imaging area determination module includes: A common imaging unit is used to perform common imaging of the coronary artery structure after the coronary angiography catheter enters the patient's coronary artery and the contrast agent is injected, thereby obtaining a basic image of the coronary artery; a difference determination unit, configured to compare the coronary artery basic image with the standard basic image to obtain an image difference; The region determination unit is used to obtain the position region where the image difference is located on the coronary artery basic image, and expand the position region based on the region size and region characteristics to obtain the target region, and use the target region as the imaging region.

3. The multimodal imaging system according to claim 1, wherein: The optical coherence tomography module comprises: a marking unit, configured to dynamically mark the imaging region based on regional lesion characteristics to obtain a dynamic marking sequence, and determine a scanning tracking sequence based on the dynamic marking sequence; a scanning unit, configured to determine optical scanning parameters according to the scanning tracking sequence, and optically scan the imaging area according to the optical scanning parameters to obtain a scanning data set; An image generating unit is configured to perform dispersion correction on the scanned data set to obtain a target data set, and generate an optical coherence tomography image based on the target data set.

4. A multimodal imaging system according to claim 3, characterized in that: The marking unit comprises: a marking determination unit, for performing a transverse analysis of regional lesion characteristics and marking the lesion grade on the imaging area according to the extent of the lesion; a marking sequence generating unit, configured to perform longitudinal analysis on regional lesion characteristics based on the lesion grade mark, determine position dynamic characteristics of the lesion grade mark, and dynamically mark the imaging area based on the position dynamic characteristics to obtain a dynamic marking sequence; The tracking sequence generation unit is used to determine the scanning area focus level based on the lesion level mark in the dynamic mark sequence, determine the scanning area dynamic characteristics based on the position dynamic characteristics in the dynamic mark sequence, and generate a scanning tracking sequence based on the scanning area focus level and the scanning area dynamic characteristics.

5. The multimodal imaging system according to claim 1, wherein: The ultrasonic imaging module includes: an orientation determining unit, configured to obtain orientation information of an imaging area using an orientation sensor; The ultrasonic imaging unit is used to determine ultrasonic scanning parameters based on the orientation information, and use the ultrasonic scanning parameters to perform ultrasonic scanning on the imaging area to obtain an ultrasonic imaging image.

6. The multimodal imaging system according to claim 1, wherein: The fluorescence imaging module comprises: a segmentation unit, configured to perform fluorescence detection on the imaging area to obtain a real-time fluorescence image, determine the fluorescence spectrum wavelength of the real-time fluorescence image, and segment the real-time fluorescence image based on the fluorescence spectrum wavelength to obtain a fluorescence area image containing main information; The fusion unit is used to perform saliency detection on the fluorescence area image and fuse it with the visible light image of the imaging area to obtain a fluorescence imaging image.

7. The multimodal imaging system according to claim 6, characterized in that: The fusion unit comprises: a detection unit, configured to perform saliency detection on the fluorescent region image using a saliency detection algorithm to obtain a saliency fluorescent image, and to perform saliency detection on the visible light image using a saliency detection algorithm to obtain a saliency visible light image; The image fusion unit is used to fuse the significant fluorescence image and the significant visible light image based on the image fusion technology to obtain a fluorescence imaging image.

8. The multimodal imaging system according to claim 1, wherein: The difference comparison unit includes: a weight determination unit, configured to determine a first correction weight based on the magnitude of the image feature difference, and determine a second correction weight based on the contribution of the main image feature to the diagnosis of the lesion; The correction unit is used to determine a correction scheme based on the main image features, and determine a specific correction value in the correction scheme based on the first correction weight and the second correction weight, and correct the fused imaging image according to the specific correction value to obtain an initial multimodal imaging image.

9. The multimodal imaging system according to claim 1, further comprising a coronary angiography catheter comprising: The coronary angiography catheter consists of a head end, a catheter and a catheter seat. The material of the head end is polyamide, and the material of the catheter is polyamide.

Images