A pyrromycin-loaded zein-citrus pectin nanoparticle and a preparation method thereof
CN118985898BActive Publication Date: 2026-05-29QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES) +1
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Patent Information
- Application Number
- CN202410955392.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-17
- Publication Date
- 2026-05-29
- Estimated Expiration
- 2044-07-17
AI Technical Summary
Technical Problem
Lecithin is insoluble in water and easily decomposes, which limits its application in the pharmaceutical and food fields. Zeatin nanoparticles are unstable and tend to aggregate, especially at high salt, high heat or pH values near the isoelectric point.
Method used
Using a core-shell structure with zein as the core and citrus pectin as the shell, lecithin enters the hydrophobic cavity of zein, and citrus pectin coats the surface of zein. The lecithin is embedded in zein-citrus pectin nanoparticles through a preparation method.
Benefits of technology
It improves the stability and solubility of styraxin, ensuring its safety in water applications. The preparation method is simple, green, safe, low-cost, and has good biocompatibility.
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Abstract
The present application relates to the field of food functional compounds and biomedical technology, and in particular to a preparation method of a zein-citrus pectin nanoparticle loaded with prodigiosin, comprising the following steps: dissolving zein in an ethanol aqueous solution, adding prodigiosin to obtain a zein-prodigiosin ethanol solution; dissolving citrus pectin in ultrapure water to obtain a citrus pectin solution; slowly adding the zein-prodigiosin ethanol solution to ultrapure water, mixing uniformly, removing ethanol by rotary evaporation to obtain a zein nanoparticle dispersion liquid loaded with prodigiosin; and then adding the above zein nanoparticle dispersion liquid loaded with prodigiosin to the citrus pectin solution, mixing uniformly to obtain a zein-citrus pectin nanoparticle dispersion liquid loaded with prodigiosin.
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