A continuous non-invasive blood pressure monitoring device and method including a wearable ultrasound probe

By designing a continuous non-invasive blood pressure monitoring device that includes a wearable ultrasound probe, and employing a MEMS ultrasound transducer and signal processing module, the design and signal processing challenges of wearable devices have been solved. This enables miniaturized, low-power continuous blood pressure monitoring, suitable for home and clinical environments, and provides continuous blood pressure assessment capabilities without calibration.

CN119014900BActive Publication Date: 2026-05-26ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV
Filing Date
2024-08-19
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

In existing technologies, acoustic-based continuous non-invasive blood pressure monitoring solutions face technical challenges in the design of wearable ultrasound devices and the establishment of real-time automatic ultrasound signal processing platforms, making it difficult to achieve miniaturized, integrated, flexible wearable ultrasonic transducers and automatic signal acquisition and analysis.

Method used

A continuous non-invasive blood pressure monitoring device incorporating a wearable ultrasound probe was designed. It employs a semi-flexible ultrasound probe, a wearable structure, and an ultrasound signal processing module, including a MEMS ultrasound transducer, a flexible PCB substrate, and a high-voltage pulse generation circuit. Through multi-channel arterial diameter waveform acquisition, local pulse wave velocity calculation, and continuous blood pressure conversion, it achieves automatic signal processing and blood pressure monitoring.

Benefits of technology

A miniaturized, low-power wearable ultrasound probe has been developed, suitable for home and clinical environments. It features continuous blood pressure assessment without calibration, simplifies the operation process, improves the versatility and robustness of monitoring, and reduces the computational burden.

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Abstract

This invention discloses a continuous non-invasive blood pressure monitoring device and method comprising a wearable ultrasound probe, belonging to the field of blood pressure monitoring technology. In the semi-flexible ultrasound probe, several MEMS ultrasonic transducers are fixed at equal intervals along the same axis on a flexible PCB substrate. The MEMS ultrasonic transducers are electrically connected to the flexible PCB substrate via gold wires. The flexible PCB substrate is connected to an ultrasound signal processing module via a flexible flat cable. A high-voltage pulse generation circuit in the ultrasound signal processing module generates a high-voltage pulse excitation signal, which excites different MEMS ultrasonic transducers in the semi-flexible ultrasound probe. Each MEMS ultrasonic transducer captures the reflected echo signals from the anterior and posterior walls of the blood vessel at the site of detection. These signals are then filtered, amplified, and transmitted to a host computer via a high-speed signal acquisition circuit. This invention also provides a method for processing pulse wave signals using the above-mentioned blood pressure monitoring device. Compared to other continuous blood pressure monitoring methods, this method allows for continuous blood pressure assessment without calibration.
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