Peritoneal cavity puncture device and peritoneal cavity puncture system

Abstract

The present application relates to the technical field of medical devices, and provides a peritoneal cavity puncture device and a peritoneal cavity puncture system. The peritoneal cavity puncture device includes: a puncture sleeve, a drug administration pipeline is arranged inside, and one end of the puncture sleeve is set as a puncture needle tip; an aerosol collection cover is arranged around the puncture sleeve along the circumferential direction, including a first opening, and the first opening faces the puncture needle tip; a recovery pipeline is arranged inside the aerosol collection cover, and the recovery pipeline is provided with an exhaust valve, and the exhaust valve is used to control the air pressure in the recovery pipeline; wherein the recovery pipeline and the drug administration pipeline are not connected to each other, and the recovery pipeline is negative pressure. The present application collects the aerosol leaked in the gap between the puncture hole and the puncture device through an internal negative pressure aerosol collection cover, and keeps the drug administration pipeline and the recovery pipeline relatively independent. It solves the problem in the prior art that in the state of high-pressure pneumoperitoneum, the intraperitoneal aerosol drug is easy to leak in the gap between the puncture hole and the puncture device, causing environmental pollution, and there is a risk of infecting nearby medical personnel.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and more specifically, to a peritoneal cavity puncture device and a peritoneal cavity puncture system. Background Art

[0002] The human peritoneal cavity is an irregular, closed potential cavity formed by two layers of peritoneum (parietal peritoneum and visceral peritoneum). The two layers of peritoneum are closely adjacent to each other. Under normal circumstances, they contain very little serous fluid, no gas, and are in a state of small positive or negative pressure. In clinical practice, percutaneous puncture is often required to enter the peritoneal cavity for some operations.

[0003] The current treatment of peritoneal cancer, pressurized intraperitonealaerosol chemotherapy (PIPAC) technology, is a new adjuvant method of chemotherapy. Under high-pressure pneumoperitoneum, intraperitoneal aerosol drugs are injected into the peritoneal cavity in the form of aerosol through a puncture device, which can relieve the symptoms of peritoneal metastasis and reduce the side effects of chemotherapy. However, in this treatment method, intraperitoneal aerosol drugs are prone to leak in the gap between the puncture hole and the puncture device. The leaked aerosol not only pollutes the environment, but also poses a risk of infecting nearby medical staff. Summary of the invention

[0004] The purpose of the present application is to provide a peritoneal cavity puncture device and a peritoneal cavity puncture system to solve the technical problem in the prior art that, under high-pressure pneumoperitoneum, intraperitoneal aerosol drugs are easily leaked in the gap between the puncture hole and the puncture device, causing environmental pollution and the risk of infecting nearby medical personnel.

[0005] Based on this, in the first aspect, the present application provides a peritoneal cavity puncture device, including: a puncture cannula, in which a drug administration pipeline is arranged, one end of the puncture cannula is set as a puncture needle tip, and the drug administration pipeline is connected to the outside world through the puncture needle tip; an aerosol collection cover is arranged around the puncture cannula along the circumferential direction, including a first opening, and the first opening faces the puncture needle tip; a recovery pipeline is arranged in the aerosol collection cover, and the recovery pipeline is provided with an exhaust valve, and the exhaust valve is used to control the air pressure in the recovery pipeline; wherein the recovery pipeline and the drug administration pipeline are not connected to each other, and the recovery pipeline is under negative pressure.

[0006] In this embodiment, the aerosol leaking from the gap between the puncture hole and the puncture device is collected by the internal negative pressure aerosol collection cover, thereby preventing the aerosol from spreading to the surrounding environment and infecting medical staff, thereby reducing the pollution of the surrounding environment. Keeping the drug administration pipeline and the recovery pipeline relatively independent can avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas.

[0007] In combination with the peritoneal cavity puncture device provided in the above scheme, the first opening is in the shape of a trumpet, and the trumpet is arranged in the direction of the puncture needle tip.

[0008] In this embodiment, in clinical operation, the puncture needle tip is usually inserted into the peritoneal cavity of a lying patient, leaving a puncture hole on the patient's skin tissue. The skin tissue of different patients has different tightness. Under high-pressure airflow environment, drug aerosol may leak from the puncture hole. The first opening is trumpet-shaped and faces the puncture hole on the patient's abdomen. Since there is negative pressure in the recovery pipeline, the leaked drug aerosol can be immediately sucked into the first opening to reduce the diffusion of the aerosol into the surrounding environment.

[0009] In combination with the peritoneal cavity puncture device provided in the above scheme, the aerosol collection cover is fixed to the other end of the puncture sleeve, and the other end is provided with an inlet of the drug delivery pipeline.

[0010] In this embodiment, one end of the puncture cannula is provided as a puncture needle tip, and an aerosol collection cover is fixed at the other end away from the puncture needle tip, so as to facilitate the aerosol leaking from the gap between the puncture hole and the puncturator. An inlet for a drug administration line is also provided at the other end of the puncture cannula, so that the drug administration line is arranged inside the puncture cannula through and through.

[0011] In combination with the peritoneal cavity puncture device provided in the above scheme, a needle sleeve seat is arranged at the other end of the puncture sleeve, and the inlet of the drug delivery pipeline is arranged on the needle sleeve seat; the aerosol collection cover is fixedly connected to the needle sleeve seat.

[0012] In this embodiment, the puncture needle cover is provided with a needle cover seat, which can facilitate the installation and use of the puncture needle cover and provide an installation basis for the entrance of the drug delivery pipeline. The aerosol collection cover can be fixedly arranged on the needle cover seat, and the needle cover seat can provide stable support for the aerosol collection cover.

[0013] In combination with the peritoneal cavity puncture device provided by the above scheme, the aerosol collection cover includes a collection part and a fixing part, the fixing part is fixedly connected to the needle sleeve seat, and the collection part cover is arranged outside the needle sleeve seat.

[0014] In this embodiment, the aerosol collection cover may include two parts, namely a collecting part and a fixing part. The collecting part is mainly used to collect aerosol leaked from the gap between the puncture hole and the puncture device, and the fixing part is mainly used to fix the aerosol collection cover. The fixing part is fixedly connected to the collecting part and can be integrally formed. The fixing part is fixedly connected to the needle sleeve seat, and the collecting part can be covered on the outside of the needle sleeve seat.

[0015] In combination with the peritoneal cavity puncture device provided in the above scheme, the collecting part is in a trumpet shape, and there is a gap between the collecting part and the outer wall of the needle sleeve seat, and the gap is a part of the recovery pipeline.

[0016] In this embodiment, the collecting portion may be in the shape of a bell mouth, and the aerosol leaking from the gap between the puncture hole and the puncture device may be gathered to the center of the bell mouth to prevent the leaked aerosol from spreading. A gap is left between the collecting portion and the outer wall of the needle holder, and the negative pressure in the recovery pipe may drive the aerosol to continue to enter the recovery pipe along the gap, so the gap may be regarded as a part of the recovery pipe.

[0017] In combination with the peritoneal cavity puncture device provided in the above scheme, an air inlet valve is provided at the inlet of the drug administration pipeline to control the air pressure in the drug administration pipeline.

[0018] In this embodiment, the high pressure in the drug administration pipeline reacts with the drug to make the drug into an aerosol, and the aerosol enters the peritoneal cavity to increase the coverage and uniformity of the drug and improve the utilization rate of the drug. The air pressure in the drug administration pipeline can be adjusted by the air inlet valve provided at the entrance of the drug administration pipeline so that the aerosol enters the peritoneal cavity evenly and the drug is administered continuously.

[0019] In combination with the peritoneal cavity puncture device provided in the above solution, the first opening is configured as an inlet of the recovery pipeline.

[0020] In this embodiment, the first opening can be set as the inlet of the recovery pipeline, and the inlet is in a trumpet shape, which is convenient for collecting the leaked aerosol and sucking the leaked aerosol into the recovery pipeline through negative pressure to prevent the leaked aerosol from spreading to the surrounding environment.

[0021] In combination with the peritoneal cavity puncture device provided in the above solution, the aerosol collection cover further includes a second opening, the second opening is configured as an outlet of the recovery pipeline, and the exhaust valve is disposed at the second opening.

[0022] In this embodiment, a second opening may be further provided on the aerosol collection hood, and the second opening is provided as an outlet of the recovery pipeline. The second opening is an outlet of the recovery pipeline connected to external equipment, and the collected waste gas (leaked aerosol) may be discharged through the second opening. An exhaust valve is provided at the second opening to control the air pressure in the recovery pipeline, so as to ensure that the air pressure in the recovery pipeline is always negative pressure, thereby preventing the leakage of aerosol waste gas from spreading.

[0023] In combination with the peritoneal cavity puncture device provided in the above scheme, the second opening is arranged on the collecting part so that the aerosol can enter the recovery pipeline through a shorter path, thereby reducing the risk of aerosol waste gas diffusion.

[0024] In combination with the peritoneal cavity puncture device provided in the above solution, the second opening can also be arranged on the fixing part.

[0025] In a second aspect, the present application provides a peritoneal cavity puncture system, comprising a drug administration device, a waste gas treatment device, and the peritoneal cavity puncture device as described above; wherein the drug administration device is connected to the drug administration pipeline, and the waste gas treatment device is connected to the recovery pipeline.

[0026] In this embodiment, the peritoneal cavity puncture system can use the negative pressure aerosol collection cover inside the above-mentioned peritoneal puncture device to collect the aerosol leaked from the gap between the puncture hole and the puncture device, and keep the drug administration pipeline and the recovery pipeline relatively independent. The drug administration pipeline and the recovery pipeline control the internal air pressure through the air intake valve and the exhaust valve respectively to avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas. In the state of high-pressure pneumoperitoneum, it is avoided that the intraperitoneal aerosol drug is easy to leak in the gap between the puncture hole and the puncture device to pollute the environment, and the risk of infecting nearby medical staff is effectively reduced.

[0027] In combination with the peritoneal cavity puncture system provided in the above scheme, the drug administration device is connected to the air inlet valve on the drug administration pipeline, and the waste gas treatment device is connected to the exhaust valve on the recovery pipeline.

[0028] In combination with the peritoneal cavity puncture system provided in the above scheme, the waste gas treatment device is a multifunctional pneumoperitoneum machine or a hospital waste gas recovery system, or a combination of both.

[0029] The beneficial effects of a peritoneal cavity puncture device and a peritoneal cavity puncture system provided by the present application are at least as follows: the present application collects the aerosol leaked from the gap between the puncture hole and the puncture device through an internal negative pressure aerosol collection cover, and keeps the drug administration pipeline and the recovery pipeline relatively independent, and the drug administration pipeline and the recovery pipeline control the internal air pressure through the air intake valve and the exhaust valve respectively, to avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas. The technical problem in the prior art that in the state of high-pressure pneumoperitoneum, the intraperitoneal aerosol drug is easy to leak in the gap between the puncture hole and the puncture device, causing environmental pollution, and there is a risk of infecting nearby medical personnel is solved. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0031] Figure 1 A schematic diagram of the structure of a peritoneal cavity puncture device provided in one embodiment of the present application;

[0032] Figure 2 A schematic diagram of the clinical operation of the peritoneal cavity puncture device provided in one embodiment of the present application;

[0033] Figure 3 A schematic diagram of the structure of an aerosol collection hood provided in one embodiment of the present application;

[0034] Figure 4 A schematic diagram of the structure of a puncture cannula provided in one embodiment of the present application;

[0035] Figure 5 A schematic diagram of the structure of a peritoneal cavity puncture system provided in one embodiment of the present application.

[0036] Among them, the reference numerals in the figure are:

[0037] 1. Aerosol collection cover; 2. Puncture sleeve; 101. Exhaust valve; 102. Recovery pipeline; 103. First opening; 104. Collection part; 105. Fixing part; 106. Second opening; 201. Inlet valve; 202. Drug delivery pipeline; 203. Needle sleeve seat; 204. Puncture needle tip. DETAILED DESCRIPTION

[0038] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0039] It should be noted that when a component is referred to as being "fixed on" or "disposed on" another component, it may be directly or indirectly located on the other component. When a component is referred to as being "connected to" another component, it may be directly or indirectly connected to the other component. The directions or positions indicated by the terms "upper", "lower", "left", "right", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. are based on the directions or positions shown in the accompanying drawings and are only for the convenience of description and cannot be understood as limitations on the present technical solution. The terms "first" and "second" are only used for the convenience of description and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features. "Multiple" means two or more, unless otherwise clearly and specifically defined.

[0040] PIPAC technology is a new treatment method, mainly used to treat cancers with peritoneal metastasis, such as colorectal cancer and gastric cancer. PIPAC technology sprays chemotherapy drugs in the form of aerosols under pressure in the abdominal cavity, so that the drugs can be more evenly distributed and act directly on the peritoneal surface, thereby improving the efficacy and reducing systemic side effects. Its treatment mode is diverse and can be used alone or in combination with other treatment methods. Related prospective studies and clinical trials are being widely carried out around the world.

[0041] PIPAC can be used in combination with a variety of chemotherapy drugs, such as oxaliplatin. Oxaliplatin (OX), as a standard chemotherapy drug, is commonly used in systemic chemotherapy to treat colorectal cancer. According to the treatment experience of HIPEC, OX can maintain a high perfusion fluid concentration and has a strong tissue penetration ability. However, oxaliplatin has certain toxicity to the human body and the environment. Due to the differences in tissue relaxation among different patients, aerosols containing chemotherapy drugs can easily leak through the gap between the puncture device and the puncture hole, causing pollution to medical staff and the environment.

[0042] In order to prevent drugs from infecting medical staff and polluting the surrounding environment, the present application provides a method of using the negative pressure adsorption principle to collect the leaked aerosol drugs and waste gas through a negative pressure recovery pipeline, send it to the pipeline system, and finally enter the pneumoperitoneum machine for filtration or enter the hospital waste gas pipeline system, so as to reduce the infection of medical staff and reduce pollution to the environment.

[0043] The technical solution of this application is described in detail below with reference to the accompanying drawings.

[0044] The present application provides a peritoneal cavity puncture device, such as Figure 1-4 As shown, the peritoneal cavity puncture device is used for peritoneal cavity puncture surgery, which includes: a puncture sleeve 2 and an aerosol collection cover 1, a drug administration pipeline 202 is arranged in the puncture sleeve 2, one end of the puncture sleeve 2 is arranged as a puncture needle tip 204, and the drug administration pipeline 202 is connected to the outside through the puncture needle tip 204. The aerosol collection cover 1 is arranged around the puncture sleeve 2 in a circumferential direction, and includes a first opening 103, and the first opening 103 faces the puncture needle tip 204. A recovery pipeline 102 is arranged in the aerosol collection cover 1, and the recovery pipeline 102 is provided with an exhaust valve 101, and the exhaust valve 101 is used to control the air pressure in the recovery pipeline 102. Among them, the recovery pipeline 102 and the drug administration pipeline 202 are not connected to each other, and the recovery pipeline 102 is negative pressure.

[0045] One end of the puncture cannula 2 is a puncture needle tip 204. In clinical operation, the patient lies flat, the puncture needle tip 204 is inserted into the patient's abdominal cavity, and the puncture needle tip 204 is kept between the parietal peritoneum and the visceral peritoneum, and medication is administered into the peritoneal cavity to establish pneumoperitoneum.

[0046] During the treatment process, on the one hand, the drug is evenly distributed in the peritoneal cavity in the form of aerosol through the drug delivery pipeline 202, and on the other hand, the aerosol leaking from the gap between the puncture device and the puncture hole is absorbed through the aerosol collection cover 1. The leaked aerosol is recovered through the recovery pipeline 102, and after passing through the exhaust valve 101, it is guided to the multifunctional pneumoperitoneum machine or the waste gas pipeline of the hospital for the next step of treatment.

[0047] The exhaust valve 101 may be disposed at the outlet (exhaust port) of the recovery pipeline 102. The exhaust valve 101 may control the flow rate of the airflow in the recovery pipeline 102, thereby controlling the air pressure in the recovery pipeline 102. In some embodiments, the air pressure in the recovery pipeline 102 may be controlled by adjusting the exhaust valve 101 as needed. It should be noted that the recovery pipeline 102 needs to maintain a negative pressure so that the aerosol enters the aerosol collection hood 1 and flows along the recovery pipeline 102 to the outlet.

[0048] The exhaust valve 101 can use a standard Luer connector and can be connected to the recovery pipeline 102. The recovery pipeline 102 can be connected to a multifunctional pneumoperitoneum machine and perform gas filtration and recovery. The pipeline can also be directly connected to the hospital waste gas recovery system.

[0049] The exhaust valve 101 also has a sealing function in the closed state.

[0050] The puncture needle tip 204 may be provided with an inclined outlet or an outlet of other shapes. The drug administration pipeline 202 passes through both ends of the puncture cannula 2 . The drug enters the drug administration pipeline 202 from one end of the puncture cannula 2 and finally flows out from the puncture needle tip 204 .

[0051] The aerosol collection cover 1 is arranged along the circumferential direction of the puncture cannula 2 and completely covers the periphery of the puncture cannula 2. A first opening 103 is arranged at one end of the aerosol collection cover 1, and the first opening 103 faces the puncture needle tip 204. The first opening 103 can be arranged at a position close to the puncture needle tip 204. In clinical operation, the closer the first opening 103 is to the leakage point, the better the suction effect is, which can further reduce the risk of the leakage aerosol spreading to the surrounding environment.

[0052] The first opening 103 may be provided as an inlet of the recovery pipeline 102. The leaked aerosol may enter the recovery pipeline 102 from the first opening 103. The inlet may be provided in a bell-mouth shape to facilitate the collection of the leaked aerosol and to suck the leaked aerosol into the recovery pipeline 102 through negative pressure, thereby preventing the leaked aerosol from diffusing to the surrounding environment.

[0053] In the embodiment of the present application, the recovery pipeline 102 and the drug administration pipeline 202 are not connected to each other, which can avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas.

[0054] In this embodiment, the aerosol leaking from the gap between the puncture hole and the puncture device can be collected by the internal negative pressure aerosol collection cover 1, thereby preventing the aerosol from spreading to the surrounding environment and infecting medical staff, thereby reducing the pollution of the surrounding environment. Keeping the drug administration pipeline 202 and the recovery pipeline 102 relatively independent can avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas.

[0055] Compared with the prior art, the embodiment of the present application adds an aerosol collection hood 1, which is connected to the exhaust valve 101 of the recovery pipeline 102, and the exhaust valve 101 can control the pressure. The embodiment of the present application has the functions of a common puncture device and a unique negative pressure waste gas recovery function through dual-pipeline control for drug administration and recovery. The exhaust and recovery systems are controlled separately, and the two intake and exhaust systems do not interfere with each other. It can effectively prevent the overflow gas from spreading in the treatment room, thereby reducing the risk of harming medical staff and the environment.

[0056] The shape of the first opening 103 can be set to be a trumpet-shaped, that is, the inner diameter gradually decreases along the wall of the aerosol collection cover 1, and the trumpet is set in the direction of the puncture needle tip 204 to facilitate the collection of leaked aerosol. In clinical operation, the puncture needle tip 204 is usually inserted into the peritoneal cavity of a lying patient. A puncture hole is left on the skin tissue of the patient. The skin tissue of different patients has different tightness. In a high-pressure airflow environment, drug aerosol may leak from the puncture hole. The first opening 103 is in a trumpet shape facing the puncture hole on the abdomen of the patient. Since the recovery pipeline 102 is under negative pressure, the leaked drug aerosol can be immediately sucked into the first opening 103 to reduce the diffusion of the aerosol into the surrounding environment.

[0057] The aerosol collection cover 1 can be fixed to the other end of the puncture sleeve 2, and the other end is provided with an inlet of the drug administration pipeline 202. One end of the puncture sleeve 2 is provided with a puncture needle tip 204, and the aerosol collection cover 1 is fixed at the other end away from the puncture needle tip 204, so as to facilitate the aerosol leaking from the gap between the puncture hole and the puncture device. The inlet of the drug administration pipeline 202 is also provided at the other end of the puncture sleeve 2, so that the drug administration pipeline 202 is arranged inside the puncture sleeve 2 through.

[0058] An air inlet valve 201 may be provided at the entrance of the drug administration line 202. The air inlet valve 201 may control the airflow velocity in the drug administration line 202, thereby controlling the air pressure in the drug administration line 202. In some embodiments, the air pressure in the drug administration line 202 may be controlled by adjusting the air inlet valve 201 as needed, thereby controlling the drug flow rate. It should be noted that the pressure in the drug administration line 202 needs to be positive pressure, which is at least higher than the intraperitoneal pressure of the patient, so that the aerosol drug can enter the peritoneal cavity of the patient through the puncture needle tip 204 at the end of the drug administration line 202.

[0059] The air inlet valve 201 can adopt a standard Luer connector and can be connected to the drug delivery pipeline 202. The air inlet valve 201 also has a sealing function when in a closed state.

[0060] In one embodiment, a needle sleeve seat 203 may be provided at the other end of the puncture cannula 2 , an inlet of the drug delivery line 202 is provided on the needle sleeve seat 203 , and the aerosol collection cover 1 is fixedly connected to the needle sleeve seat 203 .

[0061] The needle sleeve seat 203 and the puncture needle tip 204 can be integrally formed, the puncture sleeve 2 can be configured to have a structure with the puncture needle tip 204 at one end and the needle sleeve seat 203 at the other end, and the needle sleeve seat 203 can be configured to have a cylindrical structure, the diameter of which is larger than the diameter of the puncture needle tip 204. The needle sleeve seat 203 and the puncture needle tip 204 both cover the drug administration pipeline 202 and can serve as the outer wall of the drug administration pipeline 202.

[0062] The needle sleeve seat 203 can be used as a base for the puncture sleeve 2 to be connected to the outside. The outer wall of the needle sleeve seat 203 can be provided with a mounting portion or a connecting thread as needed, so that other components can be fixed on the puncture sleeve 2. As an example, the needle sleeve seat 203 can be used to fix the aerosol collection cover 1.

[0063] In this embodiment, a needle sleeve seat 203 is provided on the puncture needle sleeve, which can bring convenience to the installation and use of the puncture needle sleeve and can also provide an installation basis for the inlet of the drug delivery pipeline 202. The aerosol collection cover 1 can be fixedly provided on the needle sleeve seat 203, and the needle sleeve seat 203 can provide stable support for the aerosol collection cover 1.

[0064] In one embodiment, the aerosol collecting cover 1 may include a collecting portion 104 and a fixing portion 105 , wherein the fixing portion 105 is fixedly connected to the needle sleeve seat 203 , and the collecting portion 104 is covered on the outside of the needle sleeve seat 203 .

[0065] The collecting part 104 can be configured as a trumpet-shaped hollow cavity, that is, the inner diameter gradually decreases along the wall of the aerosol collecting hood 1, and the trumpet is arranged in the direction of the puncture needle tip 204 to facilitate the collection of leaked aerosol. Both ends of the collecting part 104 are through. The fixing part 105 can be configured as a cylindrical hollow cavity, one end of the fixing part 105 can be configured as closed, and the other end can be configured as an opening, and the outer wall of the fixing part 105 is connected to the outer wall of the collecting hood. In one example, the fixing part 105 and the collecting part 104 can be integrally formed, and the connection is smoothly transitioned. The fixing part 105 can be used as an external connection component of the aerosol collecting hood 1, and can also be used to fix the base of other functional components. In one example, the fixing part 105 can be connected to the above-mentioned needle sleeve seat 203, and the connection method includes but is not limited to a detachable connection.

[0066] The collecting part 104 is mainly used to collect leaked aerosols (waste gas). In clinical operations, there are puncture holes on the patient's skin tissue. The tightness of the skin tissue of different patients is different. In a high-pressure airflow environment, drug aerosols may leak from the puncture holes. The collecting part 104 is trumpet-shaped and faces the puncture hole on the patient's abdomen. Since there is negative pressure in the recovery pipeline 102, the leaked drug aerosol can be immediately sucked into the collecting part 104 to reduce the diffusion of the aerosol into the surrounding environment.

[0067] In this embodiment, the aerosol collecting cover 1 may include two parts, namely, a collecting part 104 and a fixing part 105. The collecting part 104 is mainly used to collect aerosol leaked from the gap between the puncture hole and the puncture device, and the fixing part 105 is mainly used to fix the aerosol collecting cover 1. The fixing part 105 is fixedly connected to the collecting part 104 and can be integrally formed. The fixing part 105 is fixedly connected to the needle sleeve seat 203, and the collecting part 104 can be covered on the outside of the needle sleeve seat 203.

[0068] In order to discharge the collected aerosol (waste gas) along the recovery pipeline 102 , a gap is provided between the collecting portion 104 and the outer wall of the needle sleeve seat 203 . The gap is a part of the recovery pipeline 102 and can serve as a path for the waste gas to flow toward the exhaust valve 101 .

[0069] The collecting part 104 is configured to be in the shape of a bell mouth, and can gather the aerosol leaking from the gap between the puncture hole and the puncture device to the center of the bell mouth to prevent the leaked aerosol from spreading. A gap is left between the collecting part 104 and the outer wall of the needle holder 203, and the negative pressure in the recovery pipe can drive the aerosol to continue to enter the recovery pipe along the gap, so the gap can be regarded as a part of the recovery pipe.

[0070] In one embodiment, the outlet of the recovery pipeline 102 may be arranged on the collection part 104, and the exhaust valve 101 is connected to the outlet, that is, the exhaust valve 101 is installed on the collection part 104. The collected leakage aerosol flows through the above-mentioned gap, is discharged from the exhaust valve 101 and enters the multifunctional pneumoperitoneum machine or the waste gas pipeline of the hospital for filtering treatment.

[0071] In another embodiment, the outlet of the recovery pipeline 102 can be arranged on the fixed part 105, and the exhaust valve 101 is connected to the outlet, that is, the exhaust valve 101 is installed on the fixed part 105. The collected leakage aerosol flows through the above-mentioned gap, is discharged from the exhaust valve 101 and enters the multifunctional pneumoperitoneum machine or the waste gas pipeline of the hospital for filtering treatment.

[0072] In one embodiment, an air inlet valve 201 may be provided at the entrance of the drug administration line 202 to control the air pressure in the drug administration line 202. The entrance of the drug administration line 202 may be provided on the needle sleeve seat 203, and the air inlet valve 201 is connected to the entrance, that is, the air inlet valve 201 is installed on the needle sleeve seat 203. The air inlet valve 201 may control the air flow rate in the drug administration line 202, thereby controlling the air pressure in the drug administration line 202. In actual clinical operation, the air inlet valve 201 may be adjusted as needed to control the air pressure in the drug administration line 202, thereby controlling the drug flow rate. It should be noted that the pressure in the drug administration line 202 needs to be positive pressure, which is at least higher than the intraperitoneal pressure of the patient, so that the aerosol drug enters the peritoneal cavity of the patient through the puncture needle tip 204 at the end of the drug administration line 202.

[0073] The high pressure in the drug delivery pipeline 202 reacts with the drug to form the drug into an aerosol, and the aerosol enters the peritoneal cavity to increase the coverage and uniformity of the drug and improve the drug utilization rate. The air pressure in the drug delivery pipeline 202 can be adjusted by the air inlet valve 201 provided at the entrance of the drug delivery pipeline 202, so that the aerosol enters the peritoneal cavity uniformly and the drug delivery is continuous.

[0074] In one embodiment, the aerosol collection hood 1 further includes a second opening 106, which is set as the outlet of the recovery pipeline 102, and the exhaust valve 101 is set at the second opening 106. In this embodiment, the aerosol collection hood 1 can also be provided with a second opening 106, which is set as the outlet of the recovery pipeline 102. The second opening 106 is the outlet of the recovery pipeline 102 connected to the external equipment, and the collected waste gas (leaked aerosol) can be discharged through the second opening 106. The exhaust valve 101 is set at the second opening 106 to control the air pressure in the recovery pipeline 102, so as to ensure that the air pressure in the recovery pipeline 102 is always negative pressure, so as to avoid the diffusion of the leaked aerosol waste gas.

[0075] The embodiment of the present application collects the aerosol leaked from the gap between the puncture hole and the puncture device through the internal negative pressure aerosol collection cover 1, and keeps the drug administration pipeline 202 and the recovery pipeline 102 relatively independent. The drug administration pipeline 202 and the recovery pipeline 102 control the internal air pressure through the air intake valve 201 and the exhaust valve 101 respectively, so as to avoid the adverse effects caused by the mixing of the drug aerosol and the leaked waste gas. The technical problem in the prior art that in the state of high-pressure pneumoperitoneum, the intraperitoneal aerosol drug is easy to leak in the gap between the puncture hole and the puncture device, causing environmental pollution and the risk of infecting nearby medical personnel is solved.

[0076] In addition, the present application also provides a peritoneal cavity puncture system, which is applied to the PIPAC technology and can be used to treat peritoneal cancer. The PIPAC technology is a treatment method based on physical principles to optimize intraperitoneal chemotherapy. The main treatment methods include the following aspects:

[0077] 1) Improve the distribution of drugs in the peritoneal cavity in the form of aerosols;

[0078] 2) Increasing intra-abdominal pressure by establishing pneumoperitoneum to counteract the fluid pressure in the tumor tissue space;

[0079] 3) restricting peritoneal blood circulation during drug administration;

[0080] 4) Improving drug utilization by controlling environmental parameters in the peritoneal cavity

[0081] The specific operation process of PIPAC is as follows:

[0082] The patient lies in a supine position, and two laparoscopic puncture devices are used to enter the abdominal cavity to establish pneumoperitoneum. First, the amount of ascites is assessed and ascites is extracted for cytology. If there is no ascites, the peritoneal cavity is lavaged and the lavage fluid is extracted for cytology. Then the abdominal cavity is explored, the peritoneal cancer index (PCI) is recorded, and at least 3 representative tissues are taken for biopsy. After confirming that there is no leakage in the abdominal cavity, PIPAC is started, and the drug is delivered into the abdominal cavity in the form of an aerosol and maintained for 30 minutes. Finally, the remaining aerosol in the abdominal cavity is discharged into the closed aerosol waste system through a particulate filter.

[0083] like Figure 5 As shown, the peritoneal cavity puncture system 500 includes a drug administration device 501, a peritoneal cavity puncture device 502, and a waste gas treatment device 503. The drug administration device 501 is connected to the drug administration pipeline, and the waste gas treatment device 503 is connected to the recovery pipeline.

[0084] The peritoneal cavity puncture device 502 in this embodiment may include: a puncture sleeve and an aerosol collection cover, wherein a drug administration pipeline is arranged in the puncture sleeve, one end of the puncture sleeve is arranged as a puncture needle tip, and the drug administration pipeline is connected to the outside through the puncture needle tip. The aerosol collection cover is arranged around the puncture sleeve in a circumferential direction, and includes a first opening, and the first opening faces the puncture needle tip. A recovery pipeline is arranged in the aerosol collection cover, and the recovery pipeline is provided with an exhaust valve, and the exhaust valve is used to control the air pressure in the recovery pipeline. Among them, the recovery pipeline and the drug administration pipeline are not connected to each other, and the recovery pipeline is under negative pressure.

[0085] The drug delivery device is connected to the air inlet valve on the drug delivery pipeline, and the waste gas treatment device is connected to the exhaust valve on the recovery pipeline. In one example, the waste gas treatment device can be a multifunctional pneumoperitoneum machine or a hospital waste gas recovery system, or a combination of the two.

[0086] During the treatment, on the one hand, the drug is evenly distributed into the peritoneal cavity in the form of aerosol through the drug delivery tube, and on the other hand, the aerosol leaking from the gap between the puncture device and the puncture hole is absorbed by the aerosol collection cover.

[0087] The puncture cannula is partially placed in the patient's abdominal cavity, and medication is administered into the peritoneal cavity to establish pneumoperitoneum. The aerosol collection hood surrounds the puncture cannula, and the opening faces the patient's puncture site. The leaked aerosol is sucked from the aerosol collection hood through the negative pressure of the recovery pipeline.

[0088] The peritoneal cavity puncture device 502 includes two independent drug administration (intake) pipelines and recovery (exhaust) pipelines. An intake valve is provided at the inlet of the drug administration pipeline to control the drug flow rate and the air pressure in the pipeline. An exhaust valve is provided at the outlet of the recovery pipeline to control the exhaust gas flow rate and the air pressure in the recovery pipeline.

[0089] The drug administration pipeline is connected to the drug administration device 501, and the drug administration device 501 can directly inject drugs into the drug administration pipeline, and the air inlet valve controls the flow rate of the drug solution. The recovery pipeline is connected to the waste gas collection device, and the waste gas collection device can filter the waste gas and perform other treatments. The waste gas collection device can be a multifunctional pneumoperitoneum machine, or a device specially used in the hospital to treat waste gas. When connected to a device specially used in the hospital to treat waste gas, it can be connected to the waste gas pipeline of the hospital through an exhaust valve set at the outlet of the recovery pipeline.

[0090] The peritoneal cavity puncture system 500 can use the negative pressure aerosol collection cover inside the peritoneal puncture device to collect the aerosol leaking from the gap between the puncture hole and the puncture device, and keep the drug administration pipeline and the recovery pipeline relatively independent. The drug administration pipeline and the recovery pipeline control the internal air pressure through the air intake valve and the exhaust valve respectively to avoid the adverse effects caused by the mixing of drug aerosol and leaked waste gas. In the state of high-pressure pneumoperitoneum, it is prevented that the intraperitoneal aerosol drug is easy to leak and pollute the environment in the gap between the puncture hole and the puncture device, and effectively reduce the risk of infecting nearby medical staff.

[0091] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims

1. A peritoneal cavity puncture device, characterized in that: include: A puncture cannula, in which a drug delivery pipeline is arranged, one end of the puncture cannula is arranged as a puncture needle tip, and the drug delivery pipeline is connected to the outside through the puncture needle tip; an aerosol collection cover, which is arranged around the puncture cannula in a circumferential direction and comprises a first opening, wherein the first opening faces the puncture needle tip; A recovery pipeline is provided in the aerosol collection hood, and an exhaust valve is provided in the recovery pipeline, and the exhaust valve is used to control the air pressure in the recovery pipeline; Wherein, the recovery pipeline is not connected to the drug administration pipeline, and the recovery pipeline is under negative pressure; The other end of the puncture cannula is provided with a needle sleeve seat. The needle sleeve seat serves as a base for the puncture sleeve to be connected to the outside, and a connecting thread is arranged on the outer wall of the needle sleeve seat so that other components can be fixed on the puncture sleeve; the aerosol collection cover is fixed on the needle sleeve seat at the other end of the puncture sleeve. The aerosol collection cover comprises a collecting part and a fixing part, the fixing part is fixedly connected to the needle sleeve seat, the collecting part cover is arranged outside the needle sleeve seat, and the inside of the aerosol collection cover is negative pressure; The collecting portion is in a bell-mouth shape, and a gap is formed between the collecting portion and the outer wall of the needle sleeve seat, and the gap is a part of the recovery pipeline; An air inlet valve is provided at the inlet of the drug administration pipeline to control the air pressure in the drug administration pipeline; The first opening is configured as an inlet of the recovery pipeline; The aerosol collecting hood further comprises a second opening, which is arranged as an outlet of the recovery pipeline, and the exhaust valve is arranged at the second opening.

2. The peritoneal cavity puncture device according to claim 1, characterized in that: The first opening is in a trumpet shape, and the trumpet is arranged toward the direction of the puncture needle tip.

3. The peritoneal cavity puncture device according to claim 1, characterized in that: The other end of the puncture cannula is provided with an inlet of the drug administration pipeline.

4. The peritoneal cavity puncture device according to claim 3, characterized in that: The inlet of the drug administration pipeline is arranged on the needle sleeve seat.

5. The peritoneal cavity puncture device according to claim 1, characterized in that: The second opening is disposed on the collecting portion.

6. The peritoneal cavity puncture device according to claim 1, characterized in that: The second opening is disposed on the fixing portion.

7. A peritoneal cavity puncture system, characterized in that: It comprises a drug delivery device, a waste gas treatment device, and a peritoneal cavity puncture device as described in any one of claims 1 to 4; The drug delivery device is communicated with the drug delivery pipeline, and the waste gas treatment device is communicated with the recovery pipeline.

8. The peritoneal cavity puncture system according to claim 7, characterized in that: The drug delivery device is connected to the air intake valve on the drug delivery pipeline, and the exhaust gas treatment device is connected to the exhaust valve on the recovery pipeline.

9. The peritoneal cavity puncture system according to claim 7 or 8, characterized in that: The waste gas treatment device is a multifunctional pneumoperitoneum machine or a hospital waste gas recovery system, or a combination of the two.

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