Traditional Chinese medicine composition for preventing hair loss, preparation method thereof, application and scalp preparation

Abstract

The present application relates to the technical field of daily chemical products, and specifically provides a traditional Chinese medicine composition for preventing hair loss, a preparation method, application and scalp preparation thereof.The traditional Chinese medicine composition for preventing hair loss comprises, in mass parts, 10-30 parts of broadleaf linden flower extract, 30-80 parts of cypress leaf extract, 10-20 parts of polygonum perfoliatum extract and 5-30 parts of ginger extract.The traditional Chinese medicine is extracted by a specific extraction method, and the extracted traditional Chinese medicines are combined to obtain the traditional Chinese medicine composition for preventing hair loss, which can improve the hair follicle environment and prevent hair loss.In addition, the traditional Chinese medicine composition can also inhibit inflammation.It can be seen that the traditional Chinese medicine composition is suitable for being applied to various types of cosmetic scalp care products and has a good industrial application prospect.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of daily chemical products, more particularly to a traditional Chinese medicine composition for preventing hair loss, a preparation method, application and scalp preparation thereof. BACKGROUND

[0002] Hair loss refers to the phenomenon of hair falling off. Normally, the hair falling off is the hair in the regression period and resting period. Since the hair in the regression period and the hair newly entering the growth period are in dynamic balance, the normal amount of hair can be maintained. In normal circumstances, the hair follicle has rich capillaries, which can absorb the nutrients necessary for hair growth from the blood, thereby ensuring the normal growth of hair. Due to metabolism, about 50-100 hairs fall off every day, but the overall amount of hair is not affected.

[0003] However, due to excessive secretion of sebaceous glands, clogging of pores and other reasons, the normal growth environment of hair is destroyed, so that the hair cannot grow normally, and serious hair loss and hair breakage occur. Specifically, there are many reasons for hair loss. Genetics is often one of the main reasons for hair loss. Changes in hormone levels may cause hair loss, such as pregnancy, childbirth, menopause, etc. For modern people, as the pace of social life accelerates and environmental pollution increases, more and more people are in a high-intensity environment of long-term stress, overtime work, and staying up late. Long-term tension and stress can cause inflammation, which in turn affects the growth cycle of hair and leads to hair loss. In addition, stress can also cause excessive secretion of sebum, causing hair follicles to atrophy and causing hair loss, and low metabolism of hair follicles and hair bulbs.

[0004] Therefore, improving inflammation and inhibiting excessive secretion of sebum are the main measures to promote hair growth. At present, the drugs for preventing hair loss mainly use chemical substances, such as finasteride, epristeride, eliandrosteride, dutasteride, ketoconazole and other western medicine ingredients. However, western medicine ingredients have strong irritation and large side effects, have a high incidence of skin allergies and dandruff, and may cause hair loss to be more serious when the drug is stopped. SUMMARY

[0005] Therefore, the present application aims to provide a traditional Chinese medicine composition for preventing hair loss, a preparation method, application and scalp preparation thereof. The traditional Chinese medicine composition for preventing hair loss of the present application uses a traditional Chinese medicine composition with low irritation and low toxicity to the human body as an active substance, which can achieve good hair loss prevention effect.

[0006] In order to achieve the above-mentioned purpose, the present application adopts the following technical solutions:

[0007] A traditional Chinese medicine composition for preventing hair loss, comprising, in parts by mass: 10-30 parts of broad-leaved linden flower extract, 30-80 parts of cypress leaf extract, 10-20 parts of polygonum perfoliatum L. extract and 5-30 parts of ginger extract.

[0008] Tilia platyphylos is a common deciduous tree belonging to the Malvaceae family, commonly found in forests of Europe and Western Asia. The flowers of Tilia platyphylos are yellow-green in color and have a sweet, fragrant aroma. They form a corymb inflorescence and bloom in summer. Tilia platyphylos flower extract is often used as a raw material for health products, cosmetics, and medicines, with antioxidant, antibacterial, and other effects.

[0009] Cupressus funebris is the leaf of the plant Cupressus funebris, commonly used in traditional Chinese medicine and health food. The medicinal value of Cupressus funebris mainly includes the following aspects: clearing heat and detoxifying: Cupressus funebris is considered by traditional Chinese medicine to have the effect of clearing heat and detoxifying, and can be used to treat cold, fever, sore throat, and other symptoms caused by external pathogens; antibacterial and anti-inflammatory: Cupressus funebris contains some active ingredients, which have certain antibacterial and anti-inflammatory effects, and can help prevent and treat infectious diseases.

[0010] Polygonum aviculare is a Polygonaceae plant, also known as Polygonum aviculare and Polygonum aviculare. According to the "Herbal Medicine", Polygonum aviculare can "fill bone marrow, brighten eyes and ears, benefit five internal organs, regulate six internal organs, open joints, treat stagnation of meridians, make people healthy and sleep, and benefit heart power". Polygonum aviculare is a common traditional Chinese medicine used in food, health products, and cosmetics, with rich value.

[0011] Zingiber officinale Roscoe is a perennial herb of the Zingiberaceae family, widely used in traditional Chinese medicine. Zingiber officinale Roscoe has various effects and functions: dispelling cold and dispelling cold: Zingiber officinale Roscoe has the effect of warming yang and dispelling cold, and is often used to relieve cold symptoms caused by internal cold; promoting digestion: Zingiber officinale Roscoe contains gingerol and other components that can stimulate the gastric mucosa, increase gastric juice secretion, and promote digestion; anti-inflammatory and anti-inflammatory: Zingiber officinale Roscoe contains curcumin and other active ingredients that have certain anti-inflammatory effects, which can relieve pain and discomfort caused by inflammation.

[0012] Preferably, the preparation method of the Tilia platyphylos flower extract comprises:

[0013] The Tilia platyphylos flowers are crushed and mixed with ethanol solution, extracted at 50-60°C for 1-2h, concentrated under reduced pressure, and the product obtained by concentration is freeze-dried to obtain Tilia platyphylos flower extract;

[0014] The solid-liquid ratio of Tilia platyphylos flowers and ethanol solution is 1:(10-25)g / mL;

[0015] The mass fraction of ethanol in the ethanol solution is 45% to 60%; more preferably, the system after the concentration under reduced pressure is concentrated into extract, 8 to 15 times of the mass of the extract of butanediol is added, and a solubilizing agent is added according to actual needs, and the solubilizing agent includes but is not limited to CO40; the extract is thick extract with a water content of 15% to 30%.

[0016] In an embodiment of the present application, the preparation method of the Tilia japonica flower extract comprises the following steps: taking Tilia japonica flowers, crushing, adding 45wt% of ethanol solution, the solid-liquid ratio of Tilia japonica flower powder and ethanol solution being 1:10 g / mL, extracting twice at 50-60℃, each time for 30 min, concentrating under reduced pressure, freezing the product at-18℃ for 24 h, and sublimating and desorbing under the conditions of-10℃, 50 Pa and 30℃, 20 Pa respectively to obtain the Tilia japonica flower extract.

[0017] Preferably, the preparation method of the Platycladus orientalis leaf extract comprises the following steps:

[0018] The Platycladus orientalis leaves are mixed with a solvent to obtain an extraction liquid, the extraction liquid is subjected to ultrasonic treatment, concentration and drying to obtain the Platycladus orientalis leaf extract.

[0019] Preferably, the solvent includes an ethanol solution; the mass fraction of ethanol in the ethanol solution is 45% to 60%; the system after the concentration is concentrated into extract, 8 to 15 times of the mass of the extract of butanediol is added, and a solubilizing agent is added according to actual needs, and the solubilizing agent includes but is not limited to CO40; the extract is thick extract with a water content of 15% to 30%.

[0020] In an embodiment of the present application, the preparation method of the Platycladus orientalis leaf extract comprises the following steps:

[0021] The Platycladus orientalis leaves are crushed and immersed in 45wt% of ethanol solution, and reflux extraction is performed, the solid-liquid ratio of the Platycladus orientalis leaf powder and the ethanol solution being 1:10 g / mL; the reflux extraction is performed three times, each time for 20 min, at a temperature of 50℃, to obtain an extraction liquid; the extraction liquid is subjected to ultrasonic treatment at 100W for 20 min, at a temperature of 50℃, centrifugation is performed to obtain supernatant, concentration is performed under reduced pressure, and drying is performed at 80℃ for 8h to obtain the Platycladus orientalis leaf extract.

[0022] Preferably, the mass fraction of ethanol in the ethanol solution is 45% to 60%; the system after the concentration under reduced pressure is concentrated into extract, 8 to 15 times of the mass of the extract of butanediol is added, and a solubilizing agent is added according to actual needs, and the solubilizing agent includes but is not limited to CO40; the extract is thick extract with a water content of 15% to 30% or dry extract with a water content of 5%.

[0023] Preferably, the preparation method of the Polygonum orientale leaf extract comprises the following steps:

[0024] The polygonum extract is obtained by mixing polygonum with a solvent, concentrating and drying the extract.

[0025] Preferably, the solvent comprises an ethanol solution; the mass fraction of ethanol in the ethanol solution is 45% to 60%; the concentrated system is concentrated into extract, 8 to 15 times the mass of the extract of butanediol is added, and a solubilizing agent is added according to actual needs, and the solubilizing agent includes but is not limited to CO40; the extract is thick extract with a water content of 15% to 30%.

[0026] In the embodiment of the present application, the preparation method of the polygonum extract comprises:

[0027] The polygonum is crushed and immersed in a 45wt% ethanol solution, and reflux extraction is performed, the material-liquid ratio of the polygonum powder and the ethanol solution is 1:10 g / mL; the reflux extraction is performed for 3 times, the extraction time of each time is 20 min, and the temperature is 50°C, to obtain an extract, the extract is concentrated under reduced pressure, and dried at 80°C for 8h to obtain the polygonum extract.

[0028] Preferably, the preparation method of the ginger extract comprises:

[0029] The ginger root is mixed with a solvent to obtain an extract, and the extract is concentrated and dried to obtain the ginger extract.

[0030] Preferably, the solvent comprises an ethanol solution; the mass fraction of ethanol in the ethanol solution is 45% to 60%; the concentrated system is concentrated into extract, 8 to 15 times the mass of the extract of butanediol is added, and a solubilizing agent is added according to actual needs, and the solubilizing agent includes but is not limited to CO40; the extract is thick extract with a water content of 15% to 30%.

[0031] In the embodiment of the present application, the preparation method of the ginger extract comprises:

[0032] The ginger root is crushed and immersed in a 45wt% ethanol solution, and reflux extraction is performed, the material-liquid ratio of the polygonum powder and the ethanol solution is 1:10 g / mL; the reflux extraction is performed for 3 times, the extraction time of each time is 20 min, and the temperature is 50°C, to obtain an extract, the extract is concentrated under reduced pressure, and dried at 80°C for 8h to obtain the polygonum extract.

[0033] Preferably, the traditional Chinese medicine composition for preventing hair loss comprises, in mass parts, 20 parts of broad-leaved linden flower extract, 70 parts of cypress leaf extract, 20 parts of polygonum extract, and 15 parts of ginger extract.

[0034] Alternatively, the traditional Chinese medicine composition for preventing hair loss comprises, in mass parts, 25 parts of broad-leaved linden flower extract, 54 parts of cypress leaf extract, 18 parts of polygonum extract, and 20 parts of ginger extract.

[0035] Alternatively, the traditional Chinese medicine composition for preventing hair loss comprises, in mass parts, Tilia japonica extract 30 parts, Biota orientalis extract 39 parts, Polygonum orientale extract 20 parts, and Zingiber officinale extract 30 parts.

[0036] The application further provides a preparation method of the traditional Chinese medicine composition for preventing hair loss, comprising:

[0037] The traditional Chinese medicine composition for preventing hair loss is prepared by mixing, in mass parts, Tilia japonica extract 10-30 parts, Biota orientalis extract 30-80 parts, Polygonum orientale extract 10-20 parts, and Zingiber officinale extract 5-30 parts.

[0038] The application further provides application of the traditional Chinese medicine composition for preventing hair loss in inhibiting inflammatory factors.

[0039] Preferably, the inflammatory factors include TNF-α and / or IL-1β.

[0040] The application further provides a scalp preparation comprising the traditional Chinese medicine composition for preventing hair loss and acceptable adjuvants.

[0041] Preferably, the content of the traditional Chinese medicine composition for preventing hair loss in the scalp preparation is 5-8 wt%.

[0042] Preferably, the adjuvants include one or more of solvents, stabilizers, humectants, and preservatives; the stabilizers include disodium EDTA; the humectants include glycerol; the preservatives include phenoxyethanol and / or methylparaben; and the solvents include water and / or butylene glycol.

[0043] Preferably, the scalp preparation includes one or more of shampoo, hair conditioner, hair mask, scalp serum, hair wax, hair spray, hair perfume, and dry cleaning powder.

[0044] In the embodiment of the application, the formula of the scalp serum comprises:

[0045] The traditional Chinese medicine composition for preventing hair loss: 5-8 wt%; butylene glycol: 2 wt%; glycerol: 0.85 wt%; phenoxyethanol: 0.4 wt%; disodium EDTA: 0.4 wt%; methylparaben: 0.15 wt%; and the balance is purified water.

[0046] Compared with the prior art, the present application adopts a specific extraction method to extract traditional Chinese medicines, and a traditional Chinese medicine composition for preventing hair loss is obtained after combination, which comprises Tilia japonica extract, Biota orientalis leaf extract, ginger extract and Polygonum orientale extract. The traditional Chinese medicine composition can improve the environment of hair follicles, inhibit hair loss, and also inhibit inflammation to a certain extent. It can be seen that the traditional Chinese medicine composition for preventing hair loss has good hair loss prevention effect, low irritation and low toxicity to the human body, and is suitable for application in various types of scalp care cosmetics, and has good industrial application prospect. DETAILED DESCRIPTION

[0047] The technical solutions of the present application will be clearly and completely described below in combination with the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0048] In order to further illustrate the present application, the following examples are used for detailed description. The raw materials used in the following examples and comparative examples of the present application are all commercially available.

[0049] Example 1

[0050] The traditional Chinese medicine composition for preventing hair loss of the present embodiment is composed of the following components: Tilia japonica extract 20g, Biota orientalis leaf extract 70g, Polygonum orientale extract 20g and ginger extract 15g.

[0051] The preparation method of the above-mentioned Tilia japonica extract comprises the following steps:

[0052] Tilia japonica is taken, 45wt% ethanol solution is added, the solid-liquid ratio of Tilia japonica and ethanol solution is 1:10g / mL, extraction is carried out at 60℃ for 2 times, each time for 30min, vacuum concentration, the product is frozen at-18℃ for 24h, and the sublimation and analysis drying conditions are-10℃, 50Pa and 30℃, 20Pa respectively, to obtain Tilia japonica extract.

[0053] The preparation method of the above-mentioned Biota orientalis leaf extract comprises the following steps:

[0054] Biota orientalis leaves are crushed and immersed in 45wt% ethanol solution, reflux extraction is carried out, the solid-liquid ratio of Biota orientalis leaf powder and ethanol solution is 1:10g / mL; reflux extraction is carried out for 3 times, each time for 20min, and the temperature is 50℃, to obtain an extraction liquid; the extraction liquid is treated with ultrasonic at 100W for 20min, the temperature is 50℃, centrifugation is carried out to obtain the upper clear liquid, extraction liquid is obtained, vacuum concentration is carried out, and drying is carried out at 80℃ for 8h, to obtain Biota orientalis leaf extract.

[0055] The preparation method of the Polygonum multiflorum Thunb. extract comprises the following steps:

[0056] The Polygonum multiflorum Thunb. is crushed, immersed in a 45 wt% ethanol solution, and subjected to reflux extraction, with a solid-liquid ratio of the Polygonum multiflorum Thunb. powder and the ethanol solution being 1:10 g / mL; the reflux extraction is performed for 3 times, with an extraction time of 20 min and a temperature of 50 DEG C each time, to obtain an extraction liquid; the extraction liquid is concentrated under reduced pressure and dried at 80 DEG C for 8 h to obtain the Polygonum multiflorum Thunb. extract.

[0057] The preparation method of the Polygonum multiflorum Thunb. extract comprises the following steps:

[0058] The Polygonum multiflorum Thunb. is crushed, immersed in a 45 wt% ethanol solution, and subjected to reflux extraction, with a solid-liquid ratio of the Polygonum multiflorum Thunb. powder and the ethanol solution being 1:10 g / mL; the reflux extraction is performed for 3 times, with an extraction time of 20 min and a temperature of 50 DEG C each time, to obtain an extraction liquid; the extraction liquid is concentrated under reduced pressure and dried at 80 DEG C for 8 h to obtain the Polygonum multiflorum Thunb. extract.

[0059] The preparation method of the Polygonum multiflorum Thunb. extract comprises the following steps:

[0060] Example 2

[0061] The Chinese medicine composition for preventing hair loss of the example comprises the following components: 25 g of the Tilia japonica extract, 54 g of the Biota orientalis extract, 18 g of the Polygonum multiflorum Thunb. extract and 20 g of the Zingiber officinale extract.

[0062] Example 3

[0063] The Chinese medicine composition for preventing hair loss of the example comprises the following components: 30 g of the Tilia japonica extract, 39 g of the Biota orientalis extract, 20 g of the Polygonum multiflorum Thunb. extract and 30 g of the Zingiber officinale extract.

[0064] Comparative Example 1

[0065] The Chinese medicine composition of the comparative example is different from the example 1 in that the comparative example only comprises the Tilia japonica extract, the Biota orientalis extract and the Polygonum multiflorum Thunb. extract; the Zingiber officinale extract is absent, and the amount of the Zingiber officinale extract is distributed to the corresponding components according to the proportion of the other three components.

[0066] Comparative Example 2

[0067] The Chinese medicine composition of the comparative example is different from the example 1 in that the comparative example only comprises the Tilia japonica extract, the Zingiber officinale extract and the Polygonum multiflorum Thunb. extract; the Biota orientalis extract is absent, and the amount of the Biota orientalis extract is distributed to the corresponding components according to the proportion of the other three components.

[0068] Comparative Example 3

[0069] The Chinese medicine composition of the present comparative example, compared with Example 1, is different in that the present comparative example only includes the extract of Tilia japonica flowers, the extract of Biota orientalis leaves and the extract of Zingiber officinale; the missing amount of the extract of Polygonum orientale is distributed to the corresponding components in proportion to the other three substances.

[0070] Comparative Example 4

[0071] The Chinese medicine composition of the present comparative example, compared with Example 1, is different in that the present comparative example only includes the extract of Zingiber officinale, the extract of Biota orientalis leaves and the extract of Polygonum orientale; the missing amount of the extract of Tilia japonica flowers is distributed to the corresponding components in proportion to the other two substances.

[0072] Comparative Example 5

[0073] The Chinese medicine composition of the present comparative example, compared with Example 1, is different in that the present comparative example only includes the extract of Zingiber officinale and the extract of Biota orientalis leaves; the missing amount of the extract of Tilia japonica flowers and the extract of Polygonum orientale is distributed to the corresponding components in proportion to the other two substances.

[0074] Comparative Example 6

[0075] The Chinese medicine composition of the present comparative example, compared with Example 1, is different in that the present comparative example only includes the extract of Tilia japonica flowers and the extract of Polygonum orientale; the missing amount of the extract of Zingiber officinale and the extract of Biota orientalis leaves is distributed to the corresponding components in proportion to the other two substances.

[0076] Comparative Example 7

[0077] The Chinese medicine composition of the present comparative example, compared with Example 1, is different in that the preparation method of the extract of Tilia japonica flowers of the present comparative example comprises the following steps:

[0078] Tilia japonica flowers are taken, soaked in 45% (v / v) ethanol for 6 h, the solid-liquid ratio of Tilia japonica flowers to ethanol is 1:20 g / mL, the supernatant is taken by centrifugation, 45% ethanol solution is added, the volume ratio of the supernatant to the ethanol solution is 1:8, extracted at 60°C for 2 times, 30 min each time, concentrated under reduced pressure, and the product is dried at 50°C for 12 h to obtain the extract of Tilia japonica flowers.

[0079] The remaining components and preparation methods are carried out with reference to Example 1.

[0080] Application Examples 1-3

[0081] The Chinese medicine composition for preventing hair loss prepared in the example is made into a scalp serum. The formula of the scalp serum consists of the following components: the Chinese medicine composition for preventing hair loss: 8 wt%; butylene glycol: 2 wt%; glycerol: 0.85 wt%; phenoxyethanol: 0.4 wt%; disodium EDTA: 0.4 wt%; nipagin methyl ester: 0.15 wt%; and the balance is purified water.

[0082] Application Comparative Examples 1-7

[0083] The traditional Chinese medicine composition obtained in the comparative example was made into a scalp serum. The formula of the scalp serum consisted of the following components: traditional Chinese medicine composition: 8wt%; butylene glycol: 2wt%; glycerol: 0.85wt%; phenoxyethanol: 0.4wt%; disodium EDTA: 0.4wt%; methyl paraben: 0.15wt%; and the balance was purified water.

[0084] Test Example 1

[0085] SPF level 7-week-old male C57BL / 6 mice weighing 18-20g were anesthetized, and the hair on the back of the mice was removed to induce the development of highly synchronized growth phase hair follicles. On the 9th day after the hair was removed, the mice were injected intraperitoneally with a cyclophosphamide solution at a concentration of 10mg / ml at a concentration of 80mg / kg to induce the apoptosis of all growth phase hair follicles, thereby inducing post-chemotherapy alopecia.

[0086] The 18 alopecia mice were randomly divided into 3 groups of 6 each: a model group, an example group, and a comparative example group. The model group was normal saline; the dose of the example group and the comparative example group was 2g per mouse. Each time the medicine was administered, the traditional Chinese medicine composition was dissolved in a small amount of normal saline and applied to the alopecia area using a cotton swab; from the 2nd day after the hair was removed, the medicine was administered once a day, and the administration continued until the 5th day after the cyclophosphamide modeling, for a total of 13 days.

[0087] After 7 days of cyclophosphamide modeling, the hair growth of each group was recorded and the proportion of the remaining hair area to the total area of the alopecia area was calculated. The test results are shown in Table 1.

[0088] Table 1

[0089] Group Remaining hair area ratio (%) Model group 26.4 Example 1 58.9 Example 2 60.2 Example 3 61.3 Comparative Example 1 49.7 Comparative Example 2 48.1 Comparative Example 3 42.6 Comparative Example 4 43.9 Comparative Example 5 42.7 Comparative Example 6 47.5 Comparative Example 7 50.3

[0090] As can be seen from Table 1, compared with the comparative examples, the traditional Chinese medicine composition provided in the examples of the present application can significantly alleviate alopecia caused by chemotherapeutic drugs.

[0091] Test Example 2

[0092] Ninety volunteers with symptoms of infectious alopecia, each with more than 50 hairs lost per day, were selected to participate in the test and were randomly divided into 9 groups. The products prepared using the application and the application comparative example were used as test groups, plus a control group (normal saline). The corresponding products were used once a day at a fixed time; the average number of hairs lost was calculated on the 0th, 20th, and 45th days, and the test results are shown in Table 2.

[0093] Table 2

[0094]

[0095]

[0096] As can be seen from Table 2, the product provided by the application example has a better anti-hair loss effect after 45 days of use compared with the application of the comparative example.

[0097] Test Example 3

[0098] This test example investigates the inhibitory effect of the traditional Chinese medicine composition obtained by the embodiment and the comparative example on inflammatory factors, specifically including the following steps:

[0099] (1) Take BMDMs cells in the logarithmic growth phase, inoculate in a 6-well cell culture plate, and culture in a 37℃, 5% CO2 incubator for 12h. Add LPS (100ng / mL) to induce for 24h to differentiate into a classical activated pro-inflammatory macrophage model (BMDM-M1). Add PBS to undifferentiated macrophages (BMDM-M0) as a control group.

[0100] (2) Add the composition obtained by the embodiment and the comparative example to the inflammatory cell model BMDM-M1, respectively, and culture for 24h. Collect the cells and cell supernatant of each group, respectively, and use ELISA to detect the concentration changes of pro-inflammatory factors TNF-α and IL-1β in the cell supernatant. The test results are shown in Table 3.

[0101] Table 3

[0102]

[0103]

[0104] As can be seen from Table 3, the traditional Chinese medicine composition provided by the embodiment of the application can significantly inhibit anti-inflammatory factors TNF-α and IL-1β compared with the comparative example.

Claims

1. A traditional Chinese medicine composition for preventing hair loss, characterized in that, The composition comprises, by mass fraction, 10-30 parts of broad-leaved linden flower extract, 30-80 parts of Chinese arborvitae leaf extract, 10-20 parts of polygonum perfoliatum L. extract, and 5-30 parts of ginger extract. The preparation method of the broad-leaved linden flower extract comprises: The broad-leaved linden flower is crushed, mixed with an ethanol solution, extracted at 50-60°C for 1-2 hours, concentrated under reduced pressure, and freeze-dried to obtain the broad-leaved linden flower extract. The ratio of the broad-leaved linden flower to the ethanol solution is 1:(10-25) g / mL. The volume fraction of ethanol in the ethanol solution is 45%-60%. The preparation method of the Chinese arborvitae leaf extract comprises: The Chinese arborvitae leaf is mixed with an ethanol solution to obtain an extraction liquid, and the extraction liquid is subjected to ultrasonic treatment, concentration, and drying to obtain the Chinese arborvitae leaf extract. The preparation method of the polygonum perfoliatum L. extract comprises: The polygonum perfoliatum L. is mixed with an ethanol solution to obtain an extraction liquid, and the extraction liquid is subjected to concentration and drying to obtain the polygonum perfoliatum L. extract. The preparation method of the ginger extract comprises: The ginger root is mixed with an ethanol solution to obtain an extraction liquid, and the extraction liquid is subjected to concentration and drying to obtain the ginger extract.

2. The traditional Chinese medicine composition according to claim 1, characterized in that, The composition comprises, by mass fraction, 20 parts of broad-leaved linden flower extract, 70 parts of Chinese arborvitae leaf extract, 20 parts of polygonum perfoliatum L. extract, and 15 parts of ginger extract. Alternatively, the composition for preventing hair loss comprises, by mass fraction, 25 parts of broad-leaved linden flower extract, 54 parts of Chinese arborvitae leaf extract, 18 parts of polygonum perfoliatum L. extract, and 20 parts of ginger extract. Alternatively, the composition for preventing hair loss comprises, by mass fraction, 30 parts of broad-leaved linden flower extract, 39 parts of Chinese arborvitae leaf extract, 20 parts of polygonum perfoliatum L. extract, and 30 parts of ginger extract.

3. The preparation method of the traditional Chinese medicine composition according to claim 1 or 2, characterized in that, The composition comprises, by mass fraction, 10-30 parts of broad-leaved linden flower extract, 30-80 parts of Chinese arborvitae leaf extract, 10-20 parts of polygonum perfoliatum L. extract, and 5-30 parts of ginger extract.

4. The Chinese medicine composition of claim 1 or 2 for use in the preparation of a medicament for preventing hair loss. The hair loss is prevented by inhibiting inflammatory factors. The Chinese medicine composition of claim 1 or 2, and acceptable adjuvants.

5. A scalp preparation for preventing hair loss, characterized by, The adjuvants are one or more of solvents, stabilizers, humectants, and preservatives.

6. The scalp preparation according to claim 5, characterized in that ​

Images