Freckle-removing and sunscreen traditional Chinese medicine composition and application thereof

Abstract

The invention provides a freckle-removing sunscreen traditional Chinese medicine composition and application thereof.The freckle-removing sunscreen traditional Chinese medicine composition is prepared from persimmon leaf extract, angelica sinensis extract, pseudo-ginseng extract, saffron crocus extract, centella asiatica extract and pearl powder.The active components are reasonably matched, the freckle-removing sunscreen traditional Chinese medicine composition aims at multiple targets from different mechanisms to achieve the freckle-fading and freckle-removing effects, and the freckle-removing sunscreen effect is achieved; ultraviolet rays can be effectively protected, the formation of color spots can be effectively prevented, and the spot removing and fading effects can be enhanced.

Description

Technical Field

[0001] The present invention relates to the technical field of skin care products, and in particular to a freckle-removing and sun-screening Chinese medicinal composition and application thereof. Background Art

[0002] When ultraviolet rays hit the skin, the skin will be in a state of "self-protection". By physically absorbing light waves, the activity of tyrosinase is activated to produce melanin, which reduces the damage of ultraviolet radiation to the skin. The melanocyte tissue of the skin transfers melanin to the cells of the basal layer of the epidermis. With the metabolism of the cells, it is brought to the stratum corneum and finally falls off with the keratinized cells. Excessive production of melanin will eventually accumulate in the epidermis of the skin, which can easily lead to abnormal accumulation of pigments, resulting in the formation of freckles, sun spots, dark spots, etc., and further cause aesthetic problems such as chloasma and age spots. There is a certain relationship between free radicals and the formation of spots. They can combine with unsaturated fatty acids in the body, causing black substances to accumulate in skin cells, which will form spots for a long time, and ultraviolet rays are one of the main reasons for the generation of free radicals. As can be seen from the above, ultraviolet protection has an important influence on the formation of spots. However, among the freckle-removing and whitening skin care products currently on the market, some active ingredients are not reasonably combined, the freckle-removing and whitening targets are single, the freckle-removing efficiency is low and cannot meet the needs. Moreover, most of them do not have effective sunscreen effects and cannot effectively protect against ultraviolet rays, which affects the prevention and removal of freckles. Summary of the invention

[0003] Therefore, based on the above background, the present invention proposes a freckle-removing and sun-protecting Chinese medicine composition and its application, which not only achieves the effect of removing freckles from different mechanisms and multiple targets through reasonable combination of active components, but also can effectively protect against ultraviolet rays, effectively prevent the formation of spots, and enhance the freckle-removing and sun-protecting effect.

[0004] The technical solution of the present invention is:

[0005] A freckle-removing and sun-protecting Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0006] 2-10 parts of persimmon leaf extract, 1-5 parts of angelica extract, 1-5 parts of Panax notoginseng extract, 0.1-2 parts of saffron extract, 1-5 parts of Centella asiatica extract, and 2-10 parts of pearl powder.

[0007] Preferably, it is composed of the following raw materials in parts by weight:

[0008] 10 parts of persimmon leaf extract, 3 parts of angelica extract, 2 parts of Panax notoginseng extract, 0.5 parts of saffron extract, 1 part of Centella asiatica extract, and 5 parts of pearl powder.

[0009] Preferably, it is composed of the following raw materials in parts by weight:

[0010] 10 parts of persimmon leaf extract, 2 parts of angelica extract, 3 parts of Panax notoginseng extract, 1.5 parts of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0011] Preferably, it is composed of the following raw materials in parts by weight:

[0012] 8 parts of persimmon leaf extract, 1 part of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 1 part of Centella asiatica extract, and 10 parts of pearl powder.

[0013] Furthermore, the Panax notoginseng extract is Yunnan Panax notoginseng extract.

[0014] Furthermore, the particle size of the pearl powder is less than 100 nm.

[0015] Based on the same inventive concept, the present invention provides an application of the above-mentioned freckle-removing Chinese medicine composition, which can be added with conventional auxiliary materials to be prepared into skin care products or cosmetics.

[0016] Furthermore, the skin care product is a facial cream or lotion or a sunscreen or a facial mask.

[0017] Based on the same inventive concept, the present invention also provides a freckle-removing sunscreen cream, which is prepared using the freckle-removing Chinese medicine composition as an active ingredient.

[0018] Furthermore, a freckle-removing sunscreen cream is prepared by the following raw material composition:

[0019] 2-10 parts of persimmon leaf extract, 1-5 parts of angelica extract, 1-5 parts of Panax notoginseng extract, 0.1-2 parts of saffron extract, 1-5 parts of Centella asiatica extract, 2-10 parts of pearl powder, 1-5 parts of skin penetrant, 50-75 parts of oil phase, 30-50 parts of emulsifier, 10-30 parts of co-emulsifier, 20-50 parts of deionized water, and 2-15 parts of other auxiliary agents.

[0020] Further, the oil phase is at least one of castor oil, palm oil, olive oil, cyclohexasiloxane jojoba oil, glycerin, and vaseline;

[0021] The emulsifier is at least one of cetearyl stearate and glyceryl stearate;

[0022] The auxiliary emulsifier is at least one of PEG-400, 1,2-propylene glycol, 1,3-propylene glycol, and lauryl PEG-10 tris(trimethylsiloxy)silylethyl polydimethylsiloxane.

[0023] The skin penetrant is at least one of azone, thiazone, dimethyl sulfoxide, tetrahydroperine, and natural borneol.

[0024] Other adjuvants include at least one of ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, bis-ethylhexyloxyphenol methoxyphenyl triazine, polyglyceryl-3 polydimethylsilyl hydroxyethyl polydimethicone, polydimethylsiloxane, trimethylsiloxysilicate, isononyl isononanoate, cyclopentasiloxane, cyclohexasiloxane jojoba oil, aluminum hydroxide, polymethyl silsesquioxane, methyl methacrylate crosspolymer, zinc oxide, titanium dioxide, dipotassium glycyrrhizate, tetrahydromethylpyrimidine carboxylic acid, PINUS STROBUS bark extract, phenylbenzimidazole sulfonic acid, arginine, and sodium chloride.

[0025] Persimmon leaf extract contains high content of vitamin C and plant polyphenols, which have the functions of scavenging free radicals and anti-oxidation, and inhibiting the activity of tyrosinase. It can not only inhibit the formation of melanin, but also promote the metabolism of melanin.

[0026] Angelica extract not only inhibits the formation of melanin, but also promotes blood circulation and accelerates the metabolism of melanin; it also has the functions of scavenging free radicals, anti-oxidation, and protecting cells from damage by free radicals.

[0027] Panax notoginseng extract not only promotes blood circulation and removes blood stasis, promotes the body's metabolism, but also has a certain clearing effect on pigmentation accumulation inside the skin. The notoginseng total glycosides and rich antioxidant ingredients it contains can clear oxygen free radicals, DPPH free radicals, ABTS free radicals, etc.

[0028] Saffron extract can promote blood circulation in facial skin capillaries and nourish blood, which can accelerate the metabolism of melanin. It is rich in crocin, which has strong antioxidant effects and can effectively eliminate free radicals in the body.

[0029] Centella asiatica extract can effectively isolate ultraviolet rays, play a certain role in ultraviolet protection, and has soothing, sedative and anti-inflammatory effects.

[0030] Pearl powder can not only inhibit the activity of tyrosinase and reduce the formation of melanin, but also the amino acids it contains can promote the metabolism of skin cells, clear excess free radicals, and effectively remove aging skin cells and their pigmentation. In addition, the nano-scale pearl powder has a reduced reflection area and weakened reflection ability, so it can absorb solar ultraviolet rays and play a role in sun protection.

[0031] The above technical solution has the following beneficial effects:

[0032] The present invention rationally combines active ingredients to target multiple targets through different mechanisms to achieve the effect of lightening and removing spots:

[0033] It mainly uses persimmon leaf extract and pearl powder extract to inhibit the activity of tyrosinase, effectively eliminate free radicals and reduce the formation of melanin; it also uses angelica extract, Panax notoginseng extract and saffron extract to promote blood circulation and remove blood stasis, promote blood circulation in skin capillaries, nourish blood, accelerate the metabolism of melanin and promote the effective discharge of melanin; it also uses Centella asiatica extract and Panax notoginseng extract to achieve soothing, calming and anti-inflammatory effects, which can not only avoid causing local irritation, but also inhibit inflammatory pigmentation reactions, and achieve effective freckle removal effects by targeting multiple targets through different mechanisms;

[0034] It is mainly composed of pearl powder, and works synergistically with persimmon leaf extract, angelica extract, Panax notoginseng extract, saffron extract, and Centella asiatica extract. Especially the addition of angelica extract and Panax notoginseng extract can effectively enhance the pearl powder's effective protection against ultraviolet rays, effectively prevent the formation of spots and enhance its freckle removal effect: the coumarins contained in angelica and the flavonoids contained in Panax notoginseng can convert ultraviolet light energy into heat energy and harmless light radiation, which can effectively organize the damage of ultraviolet rays to the skin and further enhance the protection against ultraviolet rays. Through protection against ultraviolet rays, the production of free radicals can be reduced, and the activation of tyrosinase activity can be avoided. The production of melanin can be reduced through prevention, the effect of freckle removal and freckle removal can be enhanced, and it can also play a certain maintenance role in the effect of freckle removal. DETAILED DESCRIPTION

[0035] In order to make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with its embodiments; it should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0036] Unless otherwise specified, the experimental methods used in the following examples are conventional methods.

[0037] Unless otherwise specified, the materials and reagents used in the following examples can be obtained from commercial sources.

[0038] Example 1: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0039] 10 parts of persimmon leaf extract, 3 parts of angelica extract, 2 parts of Panax notoginseng extract, 0.5 parts of saffron extract, 1 part of Centella asiatica extract, and 5 parts of pearl powder.

[0040] Example 2: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0041] 10 parts of persimmon leaf extract, 2 parts of angelica extract, 3 parts of Panax notoginseng extract, 1.5 parts of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0042] Embodiment 3: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0043] 8 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0044] Example 4: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0045] 5 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0046] Example 5: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0047] 2 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0048] Comparative Example 1: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0049] 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0050] Compared with Example 3, the persimmon leaf extract is removed in this example.

[0051] Comparative Example 2: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0052] 8 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, and 10 parts of pearl powder.

[0053] Compared with Example 3, the Centella asiatica extract is removed in this example.

[0054] Comparative Example 3: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0055] 13 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0056] Comparative Example 4: A freckle-removing Chinese medicine composition, which is composed of the following raw materials in parts by weight:

[0057] 8 parts of persimmon leaf extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

[0058] Compared with Example 3, the Angelica sinensis extract is removed in this example.

[0059] The particle size of the pearl powder used in Examples 1 to 5 and Comparative Examples 1 to 4 is less than 100 nm, and the Panax notoginseng extract is the Yunnan Panax notoginseng extract.

[0060] The preparation methods of the persimmon leaf extract, angelica extract, Yunnan Panax notoginseng extract, and saffron extract of Examples 1 to 5 and Comparative Examples 1 to 4 are as follows:

[0061] ① Take the raw materials separately, crush them into 80-100 mesh, add 8-12 times of their own weight of water, boil over high heat, then turn to low heat and cook for 40-60 minutes, filter, take the filtrate, and keep the residue for later use;

[0062] ② Add 6-10 times the weight of water to the residue, boil over high heat, then simmer over low heat for 40-60 minutes, filter and take the filtrate;

[0063] ③ Combine the filtrates on both sides, concentrate under reduced pressure at 60°C, and vacuum dry into powder.

[0064] The preparation methods of the Centella asiatica extracts of Examples 1 to 5 and Comparative Examples 1 to 3 are as follows:

[0065] ① Take Centella asiatica, crush it into 80-100 mesh, add 8-12 times of its own weight of water, boil it over high heat, then turn to low heat and cook for 40-60 minutes, take the filtrate and keep the residue for later use;

[0066] ② Add 6-10 times the weight of water to the residue, boil over high heat, then simmer over low heat for 40-60 minutes, filter and take the filtrate;

[0067] ③ After combining the two filtrates, the filtrate is concentrated under reduced pressure to 20-30% of the filtrate volume, and activated AB-8 resin is used for sample adsorption and elution, and the elution is sequentially condensed and vacuum dried into powder to prepare the product.

[0068] The above Examples 3 to 5 and Comparative Examples 1 to 3 were prepared into facial creams. Specifically, on the basis of the freckle removing traditional Chinese medicine composition, 1 part of skin penetrant, 50 parts of oil phase, 40 parts of emulsifier, 25 parts of co-emulsifier and 38 parts of deionized water were added, wherein vaseline was selected as the oil phase, cetyl stearate was selected as the emulsifier, PEG-400 was selected as the co-emulsifier, and azone was selected as the skin penetrant.

[0069] The preparation operation is as follows:

[0070] Take persimmon leaf extract, angelica extract, Panax notoginseng extract, saffron extract, and Centella asiatica extract, add them into deionized water, stir and dissolve, and prepare an extract solution;

[0071] Heat the vaseline and melt it into liquid, add the extract solution and pearl powder, then add the emulsifier, co-emulsifier and skin penetrating agent, heat and stir evenly, then cool.

[0072] Performance characterization related tests:

[0073] (1) Experimental tests were performed on the tyrosinase activity inhibition and free radical scavenging of the freckle removing Chinese medicinal compositions of Examples 3 to 5 and Comparative Examples 1 to 4:

[0074] ① The operation of inhibiting the activity of active tyrosinase is shown in (reference to Han Meizi, Jiang Xiaotian, et al., "Preparation of Atractylodes macrocephala and White Peony Root Anti-Freckle Cream", Journal of Yanbian University (Natural Science Edition, June 2021, Vol. 47, No. 2, 170-174):

[0075] The freckle-removing Chinese medicine composition was added with ultrapure water to prepare a suspension to be tested with a mass concentration of 80 mg / mL;

[0076] Prepare tyrosinase solution (0.02mol / L, pH=6.8) and L-dopa solution. Prepare 3ml of four reaction systems A, B, C, and D according to Table 1. First, incubate the PBS solution and L-dopa solution (1mmol / L) in each system in a 30℃ water bath (10min), and then add the sample solution and tyrosinase solution (200U / mL) thereto; after the components are fully mixed, measure the absorbance A of each system at a wavelength of 475nm.

[0077] The formula for calculating tyrosinase inhibition rate (I) is as follows:

[0078] I=[(A 甲1 -A 乙1 )-(A 丙1 -A 丁1 )]*100% / (A 甲1 -A 乙1 );

[0079] Table 1: Preparation of tyrosinase experimental solution system (ml)

[0080] Reaction system PBS L-Dopa Tyrosinase Suspension to be tested A1 2.0 0.5 0.5 0 B1 2.0 1 0 0 C1 1.5 0.5 0.5 0.5 Ding 1 2.0 0.5 0 0.5

[0081] ② Free radical scavenging experiment

[0082] DPPH free radical scavenging experiment

[0083] Take 2.0 mg of DPPH powder and dissolve it in 50 mL of anhydrous ethanol to obtain a DPPH solution. Add 100 μL of DPPH solution to a 96-well plate, add the suspended sample solution to be tested according to Table 2, incubate in a 37°C constant temperature shaker in the dark for 30 minutes, measure the absorbance A at a wavelength of 517 nm, and measure 4 times in parallel.

[0084] The calculation formula of DPPH free radical scavenging rate is as follows:

[0085] DPPH free radical scavenging rate (%) = [A 甲2 -(A 乙2 -A 丙2 )]*100% / A 甲2

[0086] Table 2: DPPH free radical scavenging experiment preparation

[0087] Reaction system A2 100 μL DPPH solution 100 μL absolute ethanol B2 100 μL DPPH solution 100 μL suspension to be tested C2 100 μL absolute ethanol 100 μL suspension to be tested

[0088] The results are shown in Table 3 below.

[0089] Table 3:

[0090] Tyrosinase inhibition rate DPPH free radical scavenging rate Example 3 95.87 91.45 Example 4 77.32 81.26 Example 5 68.55 69.76 Comparative Example 1 39.86 42.56 Comparative Example 2 87.25 58.88 Comparative Example 3 98.44 93.11 Comparative Example 4 76.53 46.31

[0091] It can be seen from the above that the addition of persimmon leaf extract can significantly improve the tyrosinase inhibition rate and DPPH free radical scavenging rate of the composition, and when the persimmon leaf extract exceeds a certain amount, the effect of improving the tyrosinase inhibition rate and DPPH free radical scavenging rate is not obvious; the absence of angelica will significantly affect the DPPH free radical scavenging rate.

[0092] (2) Chicken embryo chorioallantoic membrane test was performed on Examples 3 to 5 and Comparative Examples 1 to 4

[0093] The chicken embryo chorioallantoic membrane test utilizes the characteristics of the intact, clear and transparent vascular system of the chorioallantoic membrane of 9-day-old chicken embryos. A certain amount of the test substance is directly contacted with the chorioallantoic membrane. After a period of time, the changes in the vascular system of the chorioallantoic membrane, namely bleeding, coagulation, and vascular dissolution, are observed, so as to detect the eye irritation of the sample using the chicken embryo test method.

[0094] This experiment was conducted in accordance with the “Chicken Embryo Chorioallantoic Membrane Test for Eye Irritation / Corrosion of Cosmetics (SN / T 2329-2009)”.

[0095] Tested substances: facial creams prepared in Examples 3 to 5 and Comparative Examples 1 to 4

[0096] Positive control group: 0.05wt% SDS solution, used to observe the changes in the blood vessels of the chick embryo chorioallantoic membrane;

[0097] Negative control group: 0.9wt% sodium chloride solution, used for flushing after the test substance and negative control.

[0098] The SDS solution and the test substance were placed in contact with the chicken embryo chorioallantoic membrane respectively, and the test substance was covered as much as possible. The changes of the chicken embryo chorioallantoic membrane were observed, and the time of bleeding, vascular dissolution and coagulation of the chicken embryo chorioallantoic membrane within 45 minutes was recorded. During this period, photos were taken continuously. Each test substance was tested in parallel three times.

[0099] Observation indicators:

[0100] Bleeding: refers to the outflow of blood from the blood vessels or capillaries of the chicken embryo chorioallantoic membrane. Bleeding can appear in various forms, such as cauliflower-like, smooth, diffuse gauze-like or punctate bleeding.

[0101] Coagulation: refers to the denaturation of intravascular and extravascular proteins, which is usually only seen in large and medium-sized blood vessels and does not include changes in capillaries.

[0102] Vascular melting: refers to the disappearance of blood vessels on the chick embryo chorioallantoic membrane, which may be caused by multiple factors such as bleeding and changes in vascular wall tension.

[0103] The reaction time method is used to score the stimulus. The specific formula is as follows:

[0104] IS(s)=(301-T H )*5 / 300+(301-T L )*5 / 300+(301-T C )*9 / 300;

[0105] Where T H T is the average time when bleeding begins to occur on the chick embryo chorioallantoic membrane; L T is the average time when vascular melting begins to occur on the chick embryo chorioallantoic membrane; C The average time for the onset of coagulation to be observed on the chick embryo chorioallantoic membrane.

[0106] Based on the calculated IS values, classify the eye irritation of the test substances according to Table 4.

[0107] Table 4: Evaluation of stimulation score results

[0108] Stimulus score Irritation classification IS<1 Non-irritating 1≤IS<5 Mild irritation 5≤IS<10 Moderate irritation IS ≥ 10 Strong irritant / corrosive

[0109] The results are shown in Table 5.

[0110] Table 5:

[0111] Group IS Value Stimulus Classification Example 3 0 Non-irritating Example 4 0 Non-irritating Example 5 0 Non-irritating Comparative Example 1 0 Non-irritating Comparative Example 2 4.17 Mild irritation Comparative Example 3 2.59 Mild irritation Comparative Example 4 0.23 Mild irritation

[0112] (3) Patch test

[0113] 120 volunteers were recruited and randomly divided into 8 groups by drawing lots, with 15 people in each group, of which 1 group was a control group. The creams prepared from the compositions of Examples 3 to 5 and Comparative Examples 1 to 4 were applied on several layers of folded square gauze, the length of the square gauze was 1 cm, the test creams were applied to the curved side of the forearms of the volunteers, and then the gauze was fixed with medical tape. The volunteers in the control group did not receive any treatment, and the skin condition was observed after 12 hours and 24 hours, respectively.

[0114] The grading standards for the degree of skin patch reaction are shown in Table 6.

[0115] Table 6: Patch test grading standards

[0116]

[0117]

[0118] The results are shown in Table 7:

[0119] The above ratings are averaged.

[0120] (4) The in vitro sun protection factor (SPF) of the creams of Examples 3 to 5 and Comparative Examples 1 to 4 was tested using an SPF-290 sun protection factor analyzer. The results are shown in Table 8 below.

[0121] Table 8:

[0122] Group Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 SPF 53.9 51.2 49.7 46.4 48.3 55.8 43.6

[0123] (5) The skin whitening and anti-freckle effect test was carried out according to T / ZHCA 001-2018 Cosmetic Whitening and Anti-freckle Effect Test Method, and the skin chromaticity ITA° was tested. The larger the ITA° value, the lighter the skin color, and vice versa.

[0124] The specific operations are as follows:

[0125] 140 volunteers with dull facial skin and pigmentation were recruited and randomly divided into 7 groups, with 20 people in each group.

[0126] The volunteers identified a test area on their faces, the area of ​​the test area was 2cm×2cm, and the test area was evenly smeared with the cream prepared with the compositions of Examples 3 to 5, Comparative Example 1 and Comparative Example 4, once in the morning and once in the evening. The ITA° values ​​of the test areas of the volunteers before applying the cream (initial value) and 6 weeks after applying the cream were tested. The results are shown in Table 9.

[0127] Table 9:

[0128]

[0129] Embodiment 6: A freckle-removing sunscreen cream, the raw materials for its preparation are as follows:

[0130] 5 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, 10 parts of pearl powder, 2 parts of skin penetrant, 50 parts of oil phase, 30 parts of emulsifier, 15 parts of auxiliary emulsifier, 40 parts of deionized water, and 5 parts of other auxiliary agents. The oil phase is cyclohexasiloxane jojoba oil, the emulsifier is cetyl stearate, the auxiliary emulsifier is PEG-400, the skin penetrant is azone, and other auxiliary agents are 0.5 parts of polydimethylsiloxane, 0.5 parts of trimethylsiloxysilicate, 1 part of polyglyceryl-3 polydimethylsilyl hydroxyethyl polydimethylsiloxane, 1 part of polymethyl silsesquioxane, 0.5 parts of octocrylene, 0.8 parts of bis-ethylhexyloxyphenol methoxyphenyl triazine, and 0.5 parts of phenylbenzimidazole sulfonic acid.

[0131] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A freckle-removing and sun-protecting Chinese medicine composition, characterized in that: It is composed of the following raw materials in parts by weight: 2-10 parts of persimmon leaf extract, 1-5 parts of angelica extract, 1-5 parts of Panax notoginseng extract, 0.1-2 parts of saffron extract, 1-5 parts of Centella asiatica extract, and 2-10 parts of pearl powder.

2. A freckle-removing Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 10 parts of persimmon leaf extract, 3 parts of angelica extract, 2 parts of Panax notoginseng extract, 0.5 parts of saffron extract, 1 part of Centella asiatica extract, and 5 parts of pearl powder.

3. A freckle-removing Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 10 parts of persimmon leaf extract, 2 parts of angelica extract, 3 parts of Panax notoginseng extract, 1.5 parts of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

4. A freckle-removing Chinese medicine composition according to claim 1, characterized in that: It is composed of the following raw materials in parts by weight: 8 parts of persimmon leaf extract, 3 parts of angelica extract, 1 part of Panax notoginseng extract, 1 part of saffron extract, 2 parts of Centella asiatica extract, and 10 parts of pearl powder.

5. The use of a freckle removing Chinese medicinal composition according to any one of claims 1 to 4, characterized in that: The compound can be added with conventional auxiliary materials to prepare skin care products or cosmetics.

6. The use according to claim 5, characterized in that: The skin care product is a facial cream or a lotion or a sunscreen or a facial mask.

7. A freckle-removing sunscreen cream, characterized in that: The invention is prepared by using the freckle-removing Chinese medicinal composition according to any one of claims 1 to 4 as an active ingredient.

8. The freckle-removing and sun-screening facial cream according to claim 7, characterized in that: The raw material composition of its preparation is as follows: 2-10 parts of persimmon leaf extract, 1-5 parts of angelica extract, 1-5 parts of Panax notoginseng extract, 0.1-2 parts of saffron extract, 1-5 parts of Centella asiatica extract, 2-10 parts of pearl powder, 1-5 parts of skin penetrant, 50-75 parts of oil phase, 30-50 parts of emulsifier, 10-30 parts of co-emulsifier, 20-50 parts of deionized water, and 2-15 parts of other auxiliary agents.

9. The freckle-removing and sun-screening facial cream according to claim 8, characterized in that: The oil phase component is at least one of castor oil, palm oil, olive oil, cyclohexasiloxane jojoba oil, glycerin, and vaseline; the emulsifier is at least one of cetearyl stearate and glyceryl stearate; The auxiliary emulsifier is at least one of PEG-400, 1,2-propylene glycol, 1,3-propylene glycol, and lauryl PEG-10 tris(trimethylsiloxy)silylethyl polydimethylsiloxane.

10. The freckle-removing and sun-screening facial cream according to claim 8, characterized in that: The skin penetrant is at least one of azone, thiathione, dimethyl sulfoxide, tetrahydroperine, and natural borneol; Other adjuvants include at least one of ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, bis-ethylhexyloxyphenol methoxyphenyl triazine, polyglyceryl-3 polydimethylsilyl hydroxyethyl polydimethicone, polydimethylsiloxane, trimethylsiloxysilicate, isononyl isononanoate, cyclopentasiloxane, cyclohexasiloxane jojoba oil, aluminum hydroxide, polymethyl silsesquioxane, methyl methacrylate crosspolymer, zinc oxide, titanium dioxide, dipotassium glycyrrhizate, tetrahydromethylpyrimidine carboxylic acid, PINUS STROBUS bark extract, phenylbenzimidazole sulfonic acid, arginine, and sodium chloride.

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