Traditional Chinese medicine atomizing agent with sleep aiding effect and preparation method of traditional Chinese medicine atomizing agent

Abstract

The invention discloses a traditional Chinese medicine atomizing agent with a sleep aiding effect and a preparation method thereof.The traditional Chinese medicine atomizing agent with the sleep aiding effect is prepared from, by weight, 3-8 g of spina date seeds, 1-3 g of smoked plums, 3-9 g of lilies, 1-5 g of lotus seeds, 2-10 g of cape jasmine fruits, 3-9 g of lalang grass rhizomes, 5-15 g of bamboo leaves and 5-10 g of citron. The novel administration mode of atomization administration has the advantages of being fast in effect taking, convenient to use and the like, through atomization administration, the medicine can directly act on the respiratory mucosa, metabolic loss of the medicine in the body is reduced, the medicine is rapidly absorbed, the medicine effect is exerted, and the medicine can be rapidly helped to enter the sleep state.

Description

Technical Field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine atomizer with a sleep-aiding effect and a preparation method thereof. Background Art

[0002] With the rapid development of modern society, people's pace of life is accelerating. Modern people often face multiple pressures from work, study, and life. These pressures can lead to an imbalance in people's mental state. Negative emotions such as anxiety, depression, and irritability can make it difficult for people to fall asleep or maintain sleep, or even suffer from insomnia, which has seriously affected people's physical and mental health.

[0003] At present, most people seek to improve sleep by taking oral Western medicine to help them sleep. This method has certain efficacy, but it also has problems such as side effects and dependence, which bury many hidden dangers to physical health. With the continuous development of modern medical technology, people are constantly exploring and innovating methods to treat insomnia. Research on traditional Chinese medicine for insomnia has become a field of great concern. As a treasure of traditional Chinese medicine, traditional Chinese medicine has a long history and profound cultural heritage. In long-term practice, traditional Chinese medicine has been proven to have the effect of regulating human functions and improving sleep quality. However, traditional methods of taking traditional Chinese medicine, such as oral or external use, often have limitations such as unstable absorption and slow efficacy. Therefore, it has become an important topic to study how to better apply traditional Chinese medicine to the field of sleep aids and improve its efficacy and convenience. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a Chinese medicine aerosol with a sleep-inducing effect and a preparation method thereof. Through aerosol administration, the drug can directly act on the respiratory mucosa, be rapidly absorbed and exert its efficacy, and can quickly help people enter a sleep state. In addition, aerosol administration can also avoid the first-pass effect of the liver, reduce the metabolic loss of the drug in the body, and thus improve the bioavailability of the drug.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] In a first aspect, the present invention provides a Chinese medicine aerosol with a sleep-inducing effect, wherein the Chinese medicine aerosol is composed of the following Chinese medicine raw materials: Chinese jujube seeds, black plums, lilies, lotus seeds, gardenias, Imperata roots, bamboo leaves, and citrons.

[0007] Furthermore, the above-mentioned Chinese medicine nebulizer with sleep-aiding effect contains the following weight ratio: 3g-8g of Ziziphus jujuba seeds, 1g-3g of black plums, 3g-9g of lilies, 1g-5g of lotus seeds, 2g-10g of gardenias, 3g-9g of Imperata roots, 5g-15g of bamboo leaves, and 5g-10g of citron.

[0008] Furthermore, the above-mentioned Chinese medicine aerosol with sleep-inducing effect contains the following weight ratio: 3g of Chinese jujube seeds, 1g of black plum, 3g of lily, 1g of lotus seeds, 2g of gardenia, 3g of Imperata root, 5g of bamboo leaves, and 5g of citron.

[0009] Furthermore, the above-mentioned Chinese medicine nebulizer with sleep-inducing effect contains the following weight ratio: 4g of Ziziphus jujuba seeds, 2g of black plums, 5g of lilies, 3g of lotus seeds, 5g of gardenias, 6g of Imperata roots, 10g of bamboo leaves, and 8g of citron.

[0010] Furthermore, the above-mentioned Chinese medicine nebulizer with sleep-inducing effect contains the following weight ratio: 8g of Ziziphus jujuba seeds, 3g of black plums, 9g of lilies, 5g of lotus seeds, 10g of gardenias, 9g of Imperata roots, 15g of bamboo leaves, and 10g of citron.

[0011] Furthermore, the above-mentioned Chinese medicine aerosol with sleep-inducing effect, each Chinese medicine raw material has the following efficacy and pharmacological effects:

[0012] Ziziphus jujuba seeds: nourish the liver and calm the mind, soothe the nerves and reduce sweating; have multiple pharmacological effects such as sedation and hypnosis, anti-depression, anticonvulsant, memory improvement, and anti-myocardial ischemia.

[0013] Black plum: astringes the lungs and intestines, promotes the production of body fluids and calms ascaris;

[0014] Lily: nourishes yin and moistens the lungs, clears the heart and soothes the mind; has a good therapeutic effect on symptoms such as absent-mindedness, insomnia, and depression.

[0015] Lotus seeds: dry dampness and strengthen the spleen, dispel wind and cold, nourish the spleen and stop diarrhea, benefit the kidney and astringe essence, nourish the heart and calm the mind, and help sleep;

[0016] Gardenia: It can relieve heat and relieve restlessness, clear away heat and dampness, cool blood and detoxify; it has multiple pharmacological effects such as lowering blood sugar, anti-atherosclerosis, anti-depression, liver protection and gallbladder promotion, anti-tumor, antibacterial, and protective effects on nerves

[0017] Imperata root: cools blood and stops bleeding, clears heat and promotes diuresis;

[0018] Bamboo leaves: clear away heat and relieve restlessness; promote fluid production and promote urination;

[0019] Citron: regulates qi and reduces adverse effects; relieves chest tightness and resolves phlegm.

[0020] In another aspect, the present invention provides a Chinese medicine atomizer having a sleep-aiding effect and a preparation method thereof, comprising:

[0021] Follow these steps:

[0022] S1 weighing: weighing the above Chinese medicinal materials according to the weight ratio;

[0023] S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder;

[0024] S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and extracted with boiling water under reflux for 1 hour;

[0025] S4 extraction: filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration;

[0026] S5 concentration: The water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain an extract concentrate;

[0027] S6 dissolution: dissolving the extract with propylene glycol to prepare a propylene glycol solution;

[0028] S7 prepares the finished product: propylene glycol is added to the propylene glycol solution, the propylene glycol accounts for 50%, and the remaining weight is supplemented with propylene glycol to prepare the atomized liquid.

[0029] Furthermore, in step S4, ethanol needs to be added twice, and the two alcohol precipitations are carried out overnight.

[0030] Furthermore, in step S4, the ethanol concentration needs to be increased from 40% to 70%;

[0031] Furthermore, the ratio of the propylene glycol solution added in step S7 to the propylene glycol solution prepared in step S6 is 1:1.

[0032] The effective effects of the present invention are:

[0033] The present invention provides a Chinese medicine atomizer with a sleep-inducing effect and a preparation method thereof. The Chinese medicine components are reasonably compatible and effectively coordinated. This new drug administration method using atomization has the advantages of rapid onset and convenience in use. Through atomization administration, the drug can directly act on the respiratory mucosa, be quickly absorbed and exert its efficacy, and can quickly help enter a sleep state. This drug administration method not only improves the utilization rate of the drug, but also reduces the metabolic loss of the drug in the body, thereby improving the therapeutic effect. It can fully exert its characteristics of being natural, safe, and having few side effects. DETAILED DESCRIPTION

[0034] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0035] Embodiment 1

[0036] A Chinese medicine atomizer with a sleep-inducing effect comprises the following raw materials in parts by weight: 3g of sour jujube seeds, 1g of black plum, 3g of lily, 1g of lotus seeds, 2g of gardenia, 3g of Imperata root, 5g of bamboo leaves, and 5g of citron.

[0037] A Chinese medicine atomizer with a sleep-inducing effect and a preparation method thereof: weighing each raw material medicine by weight, mixing the raw material medicines and crushing them into powder to pass through an 80-mesh sieve, extracting with boiling water reflux for 1 hour, filtering the extract, adding ethanol to the extract in two portions, and precipitating with alcohol twice overnight to increase the ethanol concentration from 40% to 70%, centrifuging the water-extracted alcohol precipitate to obtain a clear liquid, and vacuum concentrating to obtain an extract; dissolving the extract with propylene glycol to obtain a propylene glycol solution, adding glycerol to the propylene glycol solution, the glycerol accounting for 50%, and adding propylene glycol to the remaining weight to obtain an atomized liquid.

[0038] Embodiment 2

[0039] A Chinese medicine atomizer with a sleep-inducing effect comprises the following raw materials in parts by weight: 4g of sour jujube seeds, 2g of black plums, 5g of lilies, 3g of lotus seeds, 5g of gardenias, 6g of Imperata roots, 10g of bamboo leaves, and 8g of citron.

[0040] The preparation method is the same as that of Example 1.

[0041] Embodiment 3

[0042] A Chinese medicine atomizer with a sleep-inducing effect comprises the following raw materials in parts by weight: 8g of sour jujube seeds, 3g of black plums, 9g of lilies, 5g of lotus seeds, 10g of gardenias, 9g of Imperata roots, 15g of bamboo leaves, and 10g of citron.

[0043] The preparation method is the same as that of Example 1.

[0044] The above embodiments are only intended to illustrate the technical solution of the present invention rather than to limit it. The present invention is described in detail. However, it is obvious to those skilled in the art that modifications or equivalent substitutions of the technical solution of the present invention without departing from the purpose and scope of the technical solution of the present invention should be included in the scope of the claims of the present invention.

Claims

1. A Chinese medicine formula having a sleep-inducing effect, It is characterized in that Contains the following Chinese medicinal ingredients: Chinese jujube seeds, black plums, lilies, lotus seeds, gardenias, Imperata roots, bamboo leaves, and citrons.

2. The Chinese medicine prescription having a sleep-aiding effect according to claim 1, It is characterized in that It is prepared according to the following weight ratio: 3g-8g of Ziziphus jujuba seeds, 1g-3g of black plums, 3g-9g of lilies, 1g-5g of lotus seeds, 2g-10g of gardenias, 3g-9g of Imperata root, 5g-15g of bamboo leaves, and 5g-10g of citron.

3. The Chinese medicine prescription having a sleep-aiding effect according to claim 2, It is characterized in that It is prepared according to the following weight ratio: 3g of Ziziphus jujuba seeds, 1g of black plum, 3g of lily, 1g of lotus seeds, 2g of gardenia, 3g of Imperata root, 5g of bamboo leaves, and 5g of citron.

4. The Chinese medicinal formula having a sleep-aiding effect according to claim 2, It is characterized in that It is prepared according to the following weight ratio: 4g of Ziziphus jujuba seeds, 2g of black plums, 5g of lilies, 3g of lotus seeds, 5g of gardenias, 6g of Imperata roots, 10g of bamboo leaves, and 8g of citron.

5. The Chinese medicinal formula having a sleep-inducing effect according to claim 2, It is characterized in that It is prepared according to the following weight ratio: 8g of Ziziphus jujuba seeds, 3g of black plums, 9g of lilies, 5g of lotus seeds, 10g of gardenias, 9g of Imperata roots, 15g of bamboo leaves, and 10g of citron.

6. A method for preparing a Chinese medicine atomizer having a sleep-aiding effect according to any one of the above claims, It is characterized in that The following steps are involved: S1 weighing: weighing the above Chinese medicinal materials according to the weight ratio; S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder; S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and extracted with boiling water under reflux for 1 hour; S4 extraction: filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration; S5 concentration: the water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain an extract concentrate; S6 dissolution: the extract is dissolved in propylene glycol to obtain a propylene glycol solution; S7 prepares the finished product: propylene glycol is added to the propylene glycol solution, the propylene glycol accounts for 50%, and the remaining weight is supplemented with propylene glycol to prepare the atomized liquid.

7. The method for preparing the Chinese medicine aerosol liquid for preventing influenza according to claim 6, Features: In step Ethanol needs to be added to S4 twice, and the solution is precipitated overnight.

8. The method for preparing the Chinese medicine aerosol liquid for preventing influenza according to claim 6, Features: In step In S4, the ethanol concentration needs to be increased from 40% to 70%.

9. The method for preparing the Chinese medicine aerosol liquid for preventing influenza according to claim 6, Features: In step S7, glycerol is added, the glycerol accounts for 50%, and the ratio with the propylene glycol solution prepared in step S6 is 1:1.