Accurate enteral nutrition formula and infusion system for tumor patients
By designing accurate enteral nutrition formula and intelligent infusion system, the nutritional needs and safety of infusion system of tumor patients are solved, and the nutritional status and treatment effect of tumor patients are improved.
Patent Information
- Application Number
- CN202411177613.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-26
- Publication Date
- 2024-12-20
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
During the treatment process, tumor patients have deteriorated their nutritional status due to physiological and metabolic changes. Traditional nutritional support methods cannot meet their special needs. In addition, there are accuracy and safety issues in the infusion system, which affects the treatment effect and quality of life.
Designed an accurate enteral nutrition formula, containing high-quality protein, essential fatty acids, complex carbohydrates, dietary fiber, vitamins and minerals, an infusion system equipped with an intelligent monitoring module, using medical grade polyvinyl chloride and stainless steel, with Accurate control and biocompatibility ensure the rationality and safety of nutrient proportion and infusion speed.
It has achieved accurate meeting of nutritional needs of tumor patients, stabilized blood sugar and electrolyte balance, reduced complication risks, improved treatment effect and quality of life, and ensured the smooth recovery and treatment process of tumor patients.
Abstract
Description
Technical Field
[0001] The present invention belongs to the field of medical technology, and specifically relates to a precise enteral nutrition formula and infusion system for tumor patients. Background Art
[0002] In cancer treatment, patients often experience a series of physiological and metabolic changes, leading to deteriorating nutritional status and severely impacting treatment outcomes and quality of life. The rapid proliferation of tumor cells consumes significant amounts of energy and nutrients. Furthermore, treatment procedures such as surgery, radiotherapy, and chemotherapy can damage the patient's gastrointestinal tract, impairing nutrient absorption and utilization. Traditional nutritional support methods often fail to meet the specific nutritional needs of cancer patients and lack specificity and precision. Because the metabolic characteristics and physical conditions of cancer patients differ significantly from those of the general population, they require precisely designed enteral nutrition formulas and infusion systems. Previously, some nutritional formulas lacked the optimal ratio and quality of key components, such as protein, fat, and carbohydrates, effectively failing to provide the energy and nutrients required by cancer patients and failing to effectively regulate their metabolic disorders. Vitamin and mineral supplementation can be incomplete, insufficient, or inappropriately proportioned. Infusion systems, previous devices can suffer from inaccurate control of infusion rate and volume, making them unable to flexibly adjust to the patient's real-time physiological status. Furthermore, some infusion devices can be made from materials with poor biocompatibility, potentially causing discomfort or complications. Improper interface design can make connection and disassembly difficult, increasing operational risks. Poor filtration can easily lead to the intrusion of impurities and microorganisms, causing infections and other problems.
[0003] In summary, in order to improve the treatment effect and quality of life of cancer patients, it is particularly urgent and important to develop a precise enteral nutrition support solution that covers a reasonable ratio of nutrients, precise infusion control, and a safe and reliable infusion device. For example, some cancer patients suffer from severe gastrointestinal dysfunction due to treatment, and traditional nutritional support cannot meet their nutritional needs, and their physical condition continues to deteriorate; while other patients develop complications such as infection due to the inaccurate and unsafe infusion system, which affects the treatment process. These actual situations highlight the necessity of developing new precise enteral nutrition formulas and infusion systems. Summary of the Invention
[0004] The purpose of the present invention is to provide a precise enteral nutrition formula and infusion system for cancer patients, aiming to solve the problems in the prior art.
[0005] To achieve the above object, the present invention provides the following technical solutions:
[0006] A precise enteral nutrition formula for cancer patients, characterized by comprising the following ingredients: 20-30g of protein (of which high-quality protein accounts for no less than 70%, and contains an appropriate amount of branched-chain amino acids, such as leucine, isoleucine, and valine), 10-20g of fat (including essential fatty acids, such as linolenic acid and linoleic acid, wherein the ratio of ω-3 fatty acids to ω-6 fatty acids is 1:4 to 1:2), 50-70g of carbohydrates (mainly complex carbohydrates, such as cereals rich in dietary fiber, and carbohydrates with a low glycemic index account for no less than 50%), 5-10g of dietary fiber (including water-soluble and water-insoluble dietary fiber, water-soluble dietary fiber such as inulin, oligofructose, etc., and water-insoluble dietary fiber such as cellulose, lignin, etc. ), Vitamin A 500-1000IU (in the form of retinol or β-carotene, and the β-carotene conversion rate is clear), Vitamin D 200-400IU (mainly in the form of vitamin D3, and the content of vitamin D2 does not exceed 10%), Vitamin E 10-20mg (including tocopherol and tocotrienol, the content of α-tocopherol is not less than 50%), Vitamin C 50-100mg (mainly in the form of ascorbic acid, and the content of sodium ascorbate does not exceed 20%), Calcium 500-800mg (the ratio of organic calcium and inorganic calcium is 1:2, organic calcium such as calcium citrate, calcium gluconate, etc.), Iron 10-20mg (in the form of ferrous iron, which is easier to absorb, and is added together with vitamin C to improve the absorption rate of iron). The proportions of each ingredient are as follows: protein 25%, fat 15%, carbohydrates 60%, dietary fiber 8%, vitamin A 800 IU, vitamin D 300 IU, vitamin E 15 mg, vitamin C 80 mg, calcium 600 mg, and iron 15 mg. In addition, it also contains appropriate amounts of trace elements such as zinc 5-10 mg (in the form of zinc gluconate or zinc sulfate), selenium 20-50 μg (in the form of selenomethionine or sodium selenite), and magnesium 100-200 mg (in the form of magnesium oxide or magnesium sulfate) to meet the special nutritional needs of cancer patients. At the same time, the water content in the nutritional formula should be clearly defined as 150-200 mL.
[0007] As a preferred embodiment of the present invention, the protein sources are whey protein and soy protein in a ratio of 2:1; the fat sources are medium-chain triglycerides and fish oil in a ratio of 3:1. Furthermore, the whey protein is high-quality whey protein that has undergone separation and purification, and the soy protein is extracted from non-GMO soybeans. The fish oil is rich in polyunsaturated fatty acids, EPA and DHA, and has a purity of no less than 60%. Furthermore, the amino acid composition and ratio of the whey protein and soy protein, as well as the specific fatty acid composition of the medium-chain triglycerides and fish oil, should be specified.
[0008] As a preferred embodiment of the present invention, an infusion device and its associated control system can precisely control the infusion rate of the nutritional formula to 50-150 mL / h, with an infusion volume of 500-1500 mL / day. The infusion device has a moderately sized tube diameter to reduce irritation and damage to the patient's blood vessels, ranging from 2-4 mm.
[0009] As a preferred solution of the present invention, the control system is equipped with an intelligent monitoring module, which can monitor the patient's physiological indicators in real time, such as controlling the blood sugar level at
[0010] 4.4-7.2mmol / L, ensuring electrolyte balance within the normal range and automatically adjusting infusion parameters based on monitoring results. The system also monitors the patient's vital signs such as heart rate, blood pressure, and body temperature, as well as liver and kidney function indicators such as creatinine and urea nitrogen. Furthermore, it can monitor and adjust the pressure during the infusion process to prevent adverse effects on the patient caused by excessive or insufficient pressure.
[0011] As a preferred embodiment of the present invention, the infusion device is manufactured from medical-grade polyvinyl chloride and stainless steel, exhibiting excellent biocompatibility and durability. The infusion device's interface is rationally designed for easy connection and removal, and is leak-proof and infection-resistant. The filter pore size of the infusion device is no greater than 0.22 μm, effectively filtering impurities and microorganisms.
[0012] As a preferred solution of the present invention, the following steps are included:
[0013] First, the patient's physical condition is assessed to determine the required nutrients and dosages. The assessment includes the patient's weight, height, disease stage, treatment plan, dietary intake, gastrointestinal function, etc.
[0014] Then, we prepare precise enteral nutrition formula based on the evaluation results;
[0015] Finally, the nutritional formula is delivered to the patient through an infusion system, with an infusion time of 8-12 hours per day.
[0016] During the infusion, medical staff should closely monitor the patient's reactions, such as nausea, vomiting, diarrhea, and other adverse reactions, and promptly adjust the infusion rate and dosage. After the infusion, the patient's nutritional status should be reassessed to adjust the subsequent nutritional support plan.
[0017] It should also be stipulated that the infusion system should be disinfected and maintained regularly, with the disinfection frequency being at least once a week. The maintenance content should include checking the sealing of the infusion device, the accuracy of the control system, etc.
[0018] Compared with the prior art, the present invention has the following beneficial effects:
[0019] In terms of nutritional formula, the carefully formulated proportions and contents of protein, fat, carbohydrates, dietary fiber, and various vitamins and minerals can accurately meet the special nutritional needs of cancer patients. The high proportion of high-quality protein, especially the appropriate amount of branched-chain amino acids, helps maintain the patient's muscle mass and body function. The appropriate proportion of essential fatty acids, such as linolenic acid and linoleic acid, helps regulate the patient's blood lipid metabolism and inflammatory response. Complex carbohydrates are the main component, and a high proportion of carbohydrates with a low glycemic index can stabilize the patient's blood sugar level and avoid adverse effects of blood sugar fluctuations on the condition. Rich dietary fiber helps improve the patient's intestinal function and prevent constipation and other problems. Secondly, the precise control function of the infusion system is of great significance. It can accurately control the infusion rate at 50-150mL / h and the infusion volume at 500-1500mL / d to ensure that the patient receives stable and continuous nutritional support and avoid the adverse effects of excessive or insufficient nutritional input. The intelligent monitoring module can monitor the patient's condition in real time. The system automatically adjusts the infusion parameters based on the patient's physiological indicators, such as blood sugar, electrolyte balance, heart rate, blood pressure, body temperature, liver and kidney function, etc., to effectively prevent the occurrence of complications and improve the safety and effectiveness of treatment. Furthermore, the high-quality materials and reasonable design of the infusion device, such as the use of medical-grade polyvinyl chloride and stainless steel, have good biocompatibility and durability, reducing the patient's discomfort and the risk of complications. The reasonable design of the interface facilitates connection and disassembly, reducing the difficulty and risk of operation. The filter pore size is strict. In short, the comprehensive application of this set of precise enteral nutrition formula and infusion system can significantly improve the nutritional status of cancer patients, enhance the patient's physical resistance, improve the treatment effect and quality of life, and provide effective nutritional support for patients who cannot absorb nutrients normally due to gastrointestinal dysfunction, avoiding the continuous deterioration of their physical condition. At the same time, the precise and safe infusion system reduces the probability of complications such as infection, ensures the smooth progress of the treatment process, and brings new hope and protection to the recovery of cancer patients. DETAILED DESCRIPTION
[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.
[0021] Example 1
[0022] The present invention provides the following technical solutions:
[0023] A precise enteral nutrition formula for cancer patients, covering the following ingredients: 20-30g of protein (of which high-quality protein accounts for no less than 70%, and contains an appropriate amount of branched-chain amino acids, such as leucine, isoleucine and valine), 10-20g of fat (including essential fatty acids, such as linolenic acid and linoleic acid, of which the ratio of ω-3 fatty acids to ω-6 fatty acids is 1:4 to 1:2), 50-70g of carbohydrates (mainly complex carbohydrates, such as cereals rich in dietary fiber, and carbohydrates with a low glycemic index account for no less than 50%), 5-10g of dietary fiber (including water-soluble and water-insoluble dietary fiber, water-soluble dietary fiber such as inulin, oligofructose, etc., and water-insoluble dietary fiber such as cellulose, lignin, etc.), vitamins Vitamin A 500-1000 IU (in the form of retinol or β-carotene, and the β-carotene conversion rate is clear), vitamin D 200-400 IU (mainly in the form of vitamin D3, and the content of vitamin D2 does not exceed 10%), vitamin E 10-20 mg (including tocopherol and tocotrienol, with an α-tocopherol content of not less than 50%), vitamin C 50-100 mg (mainly in the form of ascorbic acid, and the content of sodium ascorbate does not exceed 20%), calcium 500-800 mg (the ratio of organic calcium to inorganic calcium is 1:2, organic calcium such as calcium citrate, calcium gluconate, etc.), iron 10-20 mg (in the form of ferrous iron, which is easier to absorb, and is added together with vitamin C to improve the absorption rate of iron). The proportions of each ingredient are as follows: protein 25%, fat 15%, carbohydrates 60%, dietary fiber 8%, vitamin A 800 IU, vitamin D 300 IU, vitamin E 15 mg, vitamin C 80 mg, calcium 600 mg, and iron 15 mg. In addition, it also contains appropriate amounts of trace elements such as zinc 5-10 mg (in the form of zinc gluconate or zinc sulfate), selenium 20-50 μg (in the form of selenomethionine or sodium selenite), and magnesium 100-200 mg (in the form of magnesium oxide or magnesium sulfate) to meet the special nutritional needs of cancer patients. At the same time, the water content in the nutritional formula should be clearly defined as 150-200 mL.
[0024] In a specific embodiment of the present invention, a carefully designed, precision enteral nutrition formula encompasses multiple ingredients, including protein, fat, carbohydrates, dietary fiber, vitamins, and minerals, with precise proportions and amounts of each ingredient. The high proportion of high-quality protein and the inclusion of branched-chain amino acids (BCAAs) help cancer patients maintain muscle mass and function, reducing muscle loss caused by the disease and treatment. The fat contains essential fatty acids, with a reasonable ratio of ω-3 to ω-6 fatty acids, which can regulate lipid metabolism and inflammatory responses, improving the patient's internal environment. The formula is primarily composed of complex carbohydrates, with a high proportion of carbohydrates with a low glycemic index, which stabilizes blood sugar levels and prevents blood sugar fluctuations that can affect cancer treatment and recovery. The rich dietary fiber improves intestinal function and prevents constipation. The appropriate vitamin and mineral supplementation meets the patient's specific nutritional needs, helps boost immunity, and promotes normal metabolism. For example, a cancer patient who was weakened after treatment maintained muscle strength, stabilized blood sugar, maintained intestinal patency, and significantly improved their physical condition after using this formula, laying a good foundation for subsequent treatment.
[0025] Specifically, the protein sources are whey protein and soy protein in a ratio of 2:1; the fat sources are medium-chain triglycerides and fish oil in a ratio of 3:1. Furthermore, the whey protein is high-quality, separated and purified, and the soy protein is extracted from non-GMO soybeans. Fish oil is rich in polyunsaturated fatty acids, EPA and DHA, and has a purity of at least 60%. Furthermore, the amino acid composition and ratio of the whey protein and soy protein, as well as the specific fatty acid composition of the medium-chain triglycerides and fish oil, should be stated.
[0026] In this embodiment, the protein sources are clearly whey protein and soy protein, with a specified ratio of 2:1. The whey protein undergoes separation and purification processes for high quality, while the soy protein is extracted from non-GMO soybeans and is highly safe. This combination not only provides high-quality amino acids but also meets the specific protein needs of cancer patients. The fat sources are medium-chain triglycerides and fish oil in a ratio of 3:1. Fish oil is rich in polyunsaturated fatty acids, EPA and DHA, and has a purity of at least 60%. Medium-chain triglycerides are easily digested and absorbed, providing patients with rapid energy. EPA and DHA have anti-inflammatory and lipid-regulating properties, helping to improve the patient's physical condition and boost immunity. For example, a cancer patient whose digestive function has weakened due to treatment may benefit from this specific protein and fat combination, resulting in improved nutrient absorption, accelerated recovery, reduced inflammatory responses, and improved treatment tolerance.
[0027] Specifically, the infusion device and its accompanying control system can precisely control the infusion rate of nutritional formula to 50-150 mL / h, with an infusion volume of 500-1500 mL / day. The infusion device's tubing is of moderate diameter, ranging from 2-4 mm, to minimize irritation and damage to the patient's blood vessels.
[0028] In this embodiment, the infusion device in the precise enteral infusion system can precisely control the infusion rate of the nutritional formula to 50-150 mL / h, and the infusion volume to 500-1500 mL / d. This precise control function is of great significance. By precisely adjusting the infusion rate and volume, it is possible to ensure that cancer patients receive stable and continuous nutritional support. An infusion rate that is too slow may lead to insufficient nutritional supply and affect the patient's recovery; an infusion rate that is too fast may increase the burden on the patient's gastrointestinal tract and cause discomfort. The appropriate infusion volume can meet the patient's daily nutritional needs while avoiding the metabolic stress caused by overnutrition. For example, a seriously ill cancer patient, after using a system that precisely controls the infusion rate and volume, has a stable nutritional supply, good gastrointestinal adaptation, and no problems such as abdominal distension and abdominal pain caused by improper infusion have occurred. His physical condition has gradually improved.
[0029] Specifically, the control system is equipped with an intelligent monitoring module that can monitor the patient's physiological indicators in real time, such as controlling blood sugar levels between 4.4 and 7.2 mmol / L, ensuring electrolyte balance within the normal range, and automatically adjusting infusion parameters based on the monitoring results. The system can also monitor the patient's vital signs such as heart rate, blood pressure, and body temperature, as well as liver and kidney function indicators such as creatinine and urea nitrogen. Furthermore, it can monitor and adjust the pressure during the infusion process to prevent adverse effects on the patient caused by excessive or insufficient pressure.
[0030] In this embodiment: The intelligent monitoring module equipped with the control system has significant advantages. It can monitor the patient's physiological indicators in real time, such as controlling the blood sugar level at 4.4-7.2mmol / L, and ensuring that the electrolyte balance is within the normal range. This is crucial for the treatment of cancer patients. High or low blood sugar will affect the patient's physical condition and treatment effect. A stable blood sugar level helps maintain normal body metabolism. Electrolyte balance plays an important role in maintaining neuromuscular function, intracellular and extracellular fluid balance, etc. At the same time, the system can also monitor vital signs such as heart rate, blood pressure, body temperature, and liver and kidney function indicators, and automatically adjust the infusion parameters based on the monitoring results, effectively preventing the occurrence of complications and improving the safety and effectiveness of treatment. For example, a cancer patient experienced blood sugar fluctuations and electrolyte imbalance during the infusion process. Due to the timely detection and automatic adjustment of the infusion parameters by the intelligent monitoring module, the condition was avoided from worsening and the smooth progress of the treatment was ensured.
[0031] Specifically, the infusion device is made of medical-grade polyvinyl chloride and stainless steel, demonstrating excellent biocompatibility and durability. The interface design is rational, allowing for easy connection and removal, and is leak-proof and infection-resistant. The filter pore size of the infusion device is no larger than 0.22 μm, effectively filtering out impurities and microorganisms.
[0032] In this embodiment: the infusion device is made of medical-grade polyvinyl chloride and stainless steel, and has good biocompatibility and durability. This means that patients are less likely to experience discomfort and complications caused by material problems during use. Materials with good biocompatibility will not cause allergic reactions or tissue rejection in patients, which helps to improve patient comfort and compliance. High durability ensures the stability and reliability of the infusion device during long-term use. The interface of the infusion device is reasonably designed, easy to connect and disassemble, reducing the difficulty and risk of operation, and reducing infusion failures caused by improper operation. The leak-proof and anti-infection functions effectively prevent the leakage of nutrient solution and the invasion of external microorganisms, reducing the probability of infection. The filter pore size is no more than 0.22μm, which can effectively filter impurities and microorganisms, further ensuring the safety of infusion. For example, a cancer patient who needs long-term nutritional infusion did not experience allergies and infections due to the use of this infusion device made of excellent materials and reasonable design. The infusion process was smooth and the body received effective nutritional support.
[0033] Specifically, the steps are as follows:
[0034] First, the patient's physical condition is assessed to determine the required nutrients and dosages. The assessment includes the patient's weight, height, disease stage, treatment plan, dietary intake, gastrointestinal function, etc.
[0035] Then, we prepare precise enteral nutrition formula based on the evaluation results;
[0036] Finally, the nutritional formula is delivered to the patient through an infusion system, with an infusion time of 8-12 hours per day.
[0037] During the infusion, medical staff should closely monitor the patient's reactions, such as nausea, vomiting, diarrhea, and other adverse reactions, and promptly adjust the infusion rate and dosage. After the infusion, the patient's nutritional status should be reassessed to adjust the subsequent nutritional support plan.
[0038] It should also be stipulated that the infusion system should be disinfected and maintained regularly, with the disinfection frequency being at least once a week. The maintenance content should include checking the sealing of the infusion device, the accuracy of the control system, etc.
[0039] In this embodiment, this comprehensive approach encompassing assessment, configuration, infusion, observation, and adjustment has multiple beneficial effects. First, a comprehensive physical assessment of the cancer patient, including weight, height, disease stage, treatment regimen, dietary intake, gastrointestinal function, and other aspects, provides an accurate and detailed basis for subsequent nutritional support. Based on the assessment results, a precise enteral nutrition formula is formulated, ensuring targeted and appropriate nutritional ingredients. The nutritional formula is delivered to the patient via an infusion system, with the infusion duration controlled to 8-12 hours per day, ensuring stable and continuous nutritional support. During the infusion process, medical staff closely monitor the patient's response and promptly adjust the infusion rate and dosage, effectively preventing the exacerbation of adverse reactions. After the infusion, the patient's nutritional status is reassessed to facilitate adjustments to the subsequent nutritional support plan, achieving dynamic optimization of nutritional support. Regular disinfection and maintenance of the infusion system ensures the safety and effectiveness of the infusion. For example, after receiving this comprehensive nutritional support plan, a cancer patient experienced significant improvement in nutritional status, enhanced resistance, enhanced treatment efficacy, and a significant improvement in quality of life.
[0040] The working principle and use process of the present invention:
[0041] A comprehensive and detailed physical condition assessment is conducted for cancer patients. This process covers many aspects, including but not limited to accurately measuring the patient's weight and height, in-depth understanding of the stage of the disease and the treatment plan adopted, detailed records of the patient's daily diet intake, and comprehensive examination of gastrointestinal function. Through these assessments, detailed and accurate physical condition information of the patient is obtained, providing a solid data foundation for subsequent nutritional support plans. Then, based on the above assessment results, a precise enteral nutrition formula is carefully configured. In this link, ingredients such as protein, fat, carbohydrates, dietary fiber, vitamins and minerals are selected strictly in accordance with the prescribed proportions and contents. Among them, the protein sources are whey protein and soy protein, which are mixed in a ratio of 2:1, and the whey protein has been separated and purified, and the soy protein is extracted from non-genetically modified soybeans; the fat sources are medium-chain triglycerides and fish oil in a ratio of 3:1. Fish oil is rich in two polyunsaturated fatty acids, EPA and DHA, with a purity of not less than 60%. At the same time, ensure the various vitamins and minerals. The variety is complete and the content is appropriate. Then, the configured nutritional formula is infused into the patient's body using the infusion system. The infusion device can accurately control the infusion rate at 50-150mL / h, the infusion volume is 500-1500mL / d, and the infusion time is 8-12h per day. During the infusion process, medical staff need to remain highly vigilant at all times and closely observe the patient for adverse reactions such as nausea, vomiting, and diarrhea. Once abnormalities occur, the infusion rate and dosage should be adjusted in time. Finally, after the infusion is completed, the patient's nutritional status is evaluated again. By comparing the evaluation results before and after, reasonable adjustments can be made to the subsequent nutritional support plan. In addition, according to regulations, the infusion system must be disinfected and maintained at least once a week. During the disinfection and maintenance process, the sealing of the infusion device should be carefully checked to ensure that there is no risk of leakage; the accuracy of the control system should be verified to ensure that it can accurately control the infusion parameters; at the same time, check whether the pore size of the filter meets the standard of no more than 0.22μm to effectively filter impurities and microorganisms and prevent infection and other adverse conditions.
[0042] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or substitute equivalents for some of the technical features. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.
Claims
1. A precise enteral nutrition formula for cancer patients, characterized in that: The following ingredients are included: 20-30g of protein (of which high-quality protein accounts for no less than 70%, and contains appropriate amounts of branched-chain amino acids, such as leucine, isoleucine and valine), 10-20g of fat (including essential fatty acids, such as linolenic acid and linoleic acid, of which the ratio of ω-3 fatty acids to ω-6 fatty acids is 1:4 to 1:2), 50-70g of carbohydrates (mainly complex carbohydrates, such as cereals rich in dietary fiber, and carbohydrates with a low glycemic index account for no less than 50%), 5-10g of dietary fiber (including water-soluble and insoluble dietary fiber, water-soluble dietary fiber such as inulin, oligofructose, etc., insoluble dietary fiber such as cellulose, lignin, etc.), 500-100g of vitamin A. 00IU (in the form of retinol or β-carotene, and the β-carotene conversion rate is clear), vitamin D200-400IU (mainly in the form of vitamin D3, and the content of vitamin D2 does not exceed 10%), vitamin E10-20mg (including tocopherol and tocotrienol, the content of α-tocopherol is not less than 50%), vitamin C50-100mg (mainly in the form of ascorbic acid, and the content of sodium ascorbate does not exceed 20%), calcium 500-800mg (the ratio of organic calcium to inorganic calcium is 1:2, organic calcium such as calcium citrate, calcium gluconate, etc.), iron 10-20mg (in the form of ferrous iron, which is easier to absorb, and added together with vitamin C to improve the absorption rate of iron). The content proportions of each ingredient are: protein 25%, fat 15%, carbohydrates 60%, dietary fiber 8%, vitamin A 800IU, vitamin D 300IU, vitamin E 15mg, vitamin C 80mg, calcium 600mg, and iron 15mg. In addition, it also contains appropriate amounts of trace elements such as zinc 5-10 mg (in the form of zinc gluconate or zinc sulfate), selenium 20-50 μg (in the form of selenomethionine or sodium selenite), and magnesium 100-200 mg (in the form of magnesium oxide or magnesium sulfate) to meet the special nutritional needs of cancer patients. At the same time, it should be clear that the water content in the nutritional formula is 150-200 mL.
2. The precise enteral nutrition formula for cancer patients according to claim 1, characterized in that: The sources of the protein are whey protein and soy protein, with a ratio of 2:1; the sources of the fat are medium-chain triglycerides and fish oil, with a ratio of 3:
1. In addition, the whey protein is selected from high-quality whey protein that has been processed by separation and purification processes, and the soy protein is protein extracted from non-genetically modified soybeans. Fish oil is rich in two polyunsaturated fatty acids, EPA and DHA, and its purity is not less than 60%. In addition, the amino acid composition and ratio of whey protein and soy protein, and the specific fatty acid composition of medium-chain triglycerides and fish oil should also be stated.
3. The precise enteral infusion system for tumor patients according to claim 2, characterized in that: The device comprises an infusion device and a control system matched therewith. The infusion device can accurately control the infusion speed of the nutritional formula to 50-150 mL / h, and the infusion volume is 500-1500 mL / d. The diameter of the infusion device is moderate to reduce the stimulation and damage to the patient's blood vessels, and the diameter ranges from 2 to 4 mm.
4. The precise enteral infusion system for tumor patients according to claim 3, characterized in that: The control system is equipped with an intelligent monitoring module that can monitor the patient's physiological indicators in real time, such as controlling blood sugar levels at 4.4-7.2mmol / L, ensuring that electrolyte balance is within the normal range, and automatically adjusting infusion parameters based on the monitoring results. The system can also monitor the patient's vital signs such as heart rate, blood pressure, body temperature, and liver and kidney function indicators such as creatinine and urea nitrogen. At the same time, the pressure during the infusion process can be monitored and adjusted to avoid adverse effects on patients caused by excessive or low pressure.
5. The precise enteral infusion system for tumor patients according to claim 4, characterized in that: The infusion device is made of medical-grade polyvinyl chloride and stainless steel, and has good biocompatibility and durability. The interface of the infusion device is reasonably designed, easy to connect and disassemble, and has leak-proof and infection-proof functions. The filter pore size of the infusion device is no greater than 0.22 μm to effectively filter impurities and microorganisms.
6. The method of the precise enteral nutrition formula for tumor patients according to claim 5 and the infusion system according to claim 3, characterized in that: The following steps are covered: First, the physical condition of the cancer patient is assessed to determine the required nutrients and dosages. The assessment includes the patient's weight, height, disease stage, treatment plan, dietary intake, gastrointestinal function, etc. Then, we configure precise enteral nutrition formula based on the evaluation results; Finally, the nutritional formula is introduced into the patient's body through an infusion system, and the infusion time is 8-12 hours a day. During the infusion process, medical staff need to closely observe the patient's reaction, such as nausea, vomiting, diarrhea and other adverse reactions, and adjust the infusion rate and dosage in time. After the infusion, the patient's nutritional status is re-evaluated in order to adjust the subsequent nutritional support plan. It should also be stipulated that the infusion system should be disinfected and maintained regularly, with the disinfection frequency being at least once a week. The maintenance content should include checking the sealing of the infusion device, the accuracy of the control system, etc.
