Traditional Chinese medicine acupuncture simulation and curative effect evaluation method

Abstract

The invention discloses a method for simulating traditional Chinese medicine acupuncture and moxibustion and evaluating a curative effect, and aims to simulate an acupuncture and moxibustion treatment process in a digital and quantitative manner and evaluate the curative effect of the acupuncture and moxibustion treatment process. The method comprises the following steps: setting viscera health state values and acupoint stimulation intensity, describing mutual generation and restriction influence and exterior and interior relation among viscera, simulating the influence of acupoint stimulation on viscera health states and the influence of eight miraculous meridians and generation and transportation of qi-blood body fluid, and evaluating the overall health state and optimal treatment time of viscera. According to the invention, the defects of incomplete consideration of elements such as human body acupoints and internal organs and insufficient dynamic change evaluation in the prior art are made up, a human body model comprehensively considering interaction of multiple factors such as internal organs, meridians and acupoints, qi, blood, body fluid and the like is established, and dynamic change of internal organ states in the acupuncture treatment process is comprehensively displayed; a theoretical basis is provided for revealing mechanism clarification of acupuncture treatment, understanding of in-vivo operation mechanism in the acupuncture process is facilitated, and discovery of new acupuncture therapy is promoted.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine acupuncture simulation and efficacy evaluation, and in particular to a method for traditional Chinese medicine acupuncture simulation and efficacy evaluation. Background Art

[0002] As a traditional treatment method, acupuncture has been widely used in the treatment of many diseases. With the development of modern science and technology, simulation and evaluation methods of acupuncture treatment have been gradually introduced to improve the scientificity and accuracy of acupuncture therapy. However, the existing acupuncture simulation and efficacy evaluation methods still have certain limitations, and it is difficult to fully and accurately reflect the effects of acupuncture treatment on the human body.

[0003] According to the authorized patent number: CN201811174461.5, an acupuncture treatment simulation training method and system, this technology mainly collects acupuncture point parameter information, generates meridians and meridian images based on the acupuncture point parameter information, and projects and displays them, so as to realize the intuitive and visual simulation display of the acupuncture treatment process. However, this method has the following defects: (1) This method only includes the physiological information of the acupuncture point, and does not include the changes in the physiological signals generated after stimulating the acupuncture point on the state of the human body's internal organs; (2) This method can only visualize the meridian system, and does not show the changes in factors such as qi, blood, and body fluids under acupuncture stimulation; (3) The human acupuncture points involved in this method are not sufficient. The 409 acupuncture points in the human body have their own functional characteristics. The functions of all acupuncture points should be considered in detail and simulated.

[0004] According to the authorized patent number: CN202011326740.6, a system and method for quantifying acupuncture techniques, this technology mainly analyzes the induced voltage fluctuations generated by the magnetic field through experimental acupuncture, so as to measure whether a person's acupuncture techniques are standard; however, this method has the following defects: (1) This method can only quantify the acupuncture techniques, but acupuncture treatment includes acupuncture and moxibustion, and there is no effective quantification method for moxibustion treatment; (2) This method only involves the quantification method, and does not mention the different stimulation amounts generated by different stimulation intensities.

[0005] The current acupuncture simulation methods and efficacy evaluation technologies have the following deficiencies:

[0006] (1) Incomplete consideration of human body elements: Existing methods do not comprehensively consider human body acupuncture points, internal organs and other elements, and fail to integrate the dynamic changes under the mutual influence of multiple elements.

[0007] (2) Insufficient evaluation of dynamic changes: Existing technologies fail to effectively evaluate and display the dynamic changes of qi, blood, body fluids, and viscera during acupuncture treatment, and lack a comprehensive evaluation of the treatment process.

[0008] (3) Lack of a comprehensive model: A human body model that comprehensively considers the interactions of multiple factors such as the internal organs, meridians, and acupoints has not been established, and it is unable to fully reflect the complex mechanism of acupuncture treatment. Summary of the invention

[0009] The purpose of the present invention is to provide a method for simulating and evaluating the efficacy of traditional Chinese medicine acupuncture in view of the defects of the prior art, so as to solve the problems raised by the above-mentioned background technology.

[0010] To achieve the above purpose, the present invention provides the following technical solution: a method for simulating and evaluating the efficacy of traditional Chinese medicine acupuncture, which aims to comprehensively display the dynamic changes of the state of internal organs during acupuncture treatment and evaluate the treatment through detailed simulation, and provide a scientific basis for revealing the mechanism of acupuncture treatment. The method comprises the following steps:

[0011] S1: Setting the health status of the internal organs: according to the different health status of the internal organs, set their ranges, including deficiency, balance and fullness;

[0012] S2: Setting acupoint stimulation intensity: Determine the stimulation intensity level of acupoints, which is divided into tonifying treatment and purgative treatment according to the deficiency and excess of the internal organs, and is subdivided into five levels of stimulation intensity: weak, slightly weak, normal, slightly strong and strong, represented by numbers 1 to 5;

[0013] S3: Describe the mutual generation and mutual restraint between the internal organs: Determine the degree of influence between the internal organs in the mutual generation and mutual restraint relationship through calculation;

[0014] S4: Describe the internal and external relationship of the zang-fu organs: Describe the mutual influence between the zang-fu organs in the internal and external relationship through calculation;

[0015] S5: Describe the effects of acupoint stimulation on the health status of internal organs: Determine the direct effects of acupoint stimulation on the health status of internal organs;

[0016] S6: Describe the generation of Qi, blood, body fluids: Through calculation, describe the generation process of Qi, blood, body fluids under the influence of different factors;

[0017] S7: Describe the effects of the eight extra meridians: Determine the total effect of stimulating a certain acupoint on the eight extra meridians through calculation;

[0018] S8: Describe the transportation process of Qi, blood, body fluids: Describe the transportation of Qi, blood, body fluids in the body through calculations;

[0019] S9: Describe the process of the internal organs absorbing qi, blood, body fluids: Determine the changes in the health status of the internal organs during the process of absorbing qi, blood, body fluids;

[0020] S10: Assess the overall health status of the internal organs and the optimal treatment time: Through calculation, assess the health status of each internal organ and determine the optimal time to stop acupuncture treatment.

[0021] As a technical preferred solution of the present invention, the viscera health status value in step S1 is set to [0.5, 5.5], specifically: [0.5, 1.5) and [1.5, 2.5) indicate that the viscera status is "deficient"; [0.5, 1.5) indicates weak in deficiency; [1.5, 2.5) indicates weak in deficiency; [2.5, 3.5] indicates that the organ status is in a balanced state; (3.5, 4.5] and (4.5, 5.5] indicate that the viscera status is "full"; (3.5, 4.5] indicates slightly strong in full; (4.5, 5.5] indicates strong in full.

[0022] The method for simulating and evaluating the therapeutic effect of acupuncture and moxibustion according to claim 1 is characterized in that: the deficiency and excess of the internal organs in step S2, the corresponding tonifying treatment and purgative treatment are represented by positive integers and negative integers, and five stimulation intensities are set respectively, specifically represented as: the stimulation intensity range of the tonifying treatment is [+1, +5], and the stimulation intensity range of the purgative treatment is [-5, -1].

[0023] As a technical preferred solution of the present invention, the calculation formula of the mutual promotion and mutual restraint effects (taking the liver, kidney and heart as an example) in step S3 is:

[0024] f H (τ′) = g·f L (τ-1)-r·f K (τ-1)+s·f H (τ-1) (1)

[0025] Among them, f H (τ′) represents the state of the mind at time τ′, f L (τ-1), f K (τ-1) and f H (τ-1) represents the states of the liver, kidney and heart at the time τ-1 respectively, g, r and s represent the parameters of the influence of mutual generation, mutual restraint and natural decay respectively, among which, τ>τ′>τ-1.

[0026] As a preferred technical solution of the present invention, the exterior-interior relationship of the internal organs in step S4 is calculated by taking the heart and small intestine as an example:

[0027] f SI (τ′)=c·f H (τ′)+s·f SI (τ-1) (2)

[0028] f H (τ″)=c·f SI (τ′)+s·f H (τ′) (3)

[0029] Among them, the state values ​​of the heart and small intestine at time τ′ and τ-1 are represented by f H (τ′) and f SI (τ-1), the parameters c and s represent the influence degree and natural decay rate of the relationship between the inside and outside, respectively. In addition, τ″ needs to satisfy τ>τ″>τ′>τ-1.

[0030] As a technical preferred solution of the present invention, the step S5 describes the effect of acupoint stimulation on the health status of internal organs, and the specific calculation formula is:

[0031]

[0032] in, Indicates the stimulation value produced by stimulating acupoints; Indicates the state of the meridian points. When the meridian points are stimulated, When the meridian points are not stimulated, Indicates the intensity of stimulation to meridian points. is a positive integer, During purgative treatment, is a negative integer, ∈[-5,-1]; e represents the influence of different stimulus intensities on the stimulus value; Indicates the state of the internal organs; w indicates the degree of influence of the stimulus value on the internal organs; and Indicates time, and

[0033] As a technical preferred solution of the present invention, the generation of qi, blood and body fluid in step S6 is affected by the following four factors: external factors, the health status of related internal organs, the health status of the middle jiao and the status of the other two. The specific calculation formula is:

[0034]

[0035] in, Indicates the amount of a certain substance in qi, blood, and body fluids; i_normal represents external factors; n represents the total number of related organs; h represents the value of health status, which is specifically set to 3.0; represents the sum of the state values ​​of the related organs; O represents the set of organs involved in the generation; It indicates the health ratio of these organs, reflecting their overall health status; Indicates the state value of the middle focus; Indicates the measure of the health of the middle focus; ∑f E_except_i (τ-1) represents the summary of the other two state values ​​except the current calculation; Indicates the evaluation of two other states besides the current one.

[0036] As a technical preferred solution of the present invention, the effect of the eight extra meridians in step S7 represents the total effect of stimulating a certain acupoint on the eight extra meridians, and the specific calculation formula is:

[0037]

[0038] in, is the stimulation value of the eight extra meridians; f TV is the stimulation value of Chong pulse;∑ k∈N f k (τ-1) is the total stimulation value of other extraordinary meridians; N is the set of extraordinary meridians excluding Chong, Ren and Du meridians; α and β represent constant parameters affecting the weights, which represent the different influences of Chong meridian, which plays an important role in energy transport.

[0039] As a technical preferred solution of the present invention, the transport process of qi, blood and body fluid described in step S8 is affected by four factors: the amount of generation, the health status of related internal organs, the health status of the upper part of the body and the influence of the eight extraordinary meridians. The specific calculation formula is:

[0040]

[0041] in, It indicates the amount of qi, blood, and body fluids delivered to the internal organs; v indicates the total number of destinations, specifically 10; A value indicating that the generated Qi, blood, and body fluids are evenly distributed to various destinations; Indicates the total state value of the related organs; O indicates the set of organs involved in the transportation; It indicates the health ratio of the internal organs, reflecting the health status of the related internal organs during the transportation process; Indicates the state value of the upper focus; It reflects the health of the upper Jiao; represents the influence of the eight extra meridians; γ represents the constant of the influence weight.

[0042] As a technical preferred solution of the present invention, the process of the internal organs absorbing qi, blood and body fluids described in step S9 includes two parts: the consumption of the internal organs themselves and the absorption and supplementation. The specific calculation formula is:

[0043]

[0044] Among them, f V (τ) is the state value of the internal organs, and It is the amount of Qi, blood, and body fluid delivered to the internal organs. Indicates the loss of the internal organs' own state. represents absorption and supplementation, q, b and f represent the parameters of the influence of qi, blood, body fluids and zang-fu organs, and m represents the degree of self-loss.

[0045] As a preferred technical solution of the present invention, the calculation formula for evaluating the overall health status of the internal organs and the optimal treatment time in step S10 is:

[0046]

[0047] Among them, the best stopping time BestTime(τ) is the moment τ when σ'(τ) is closest to 0. At this time, each organ is in the best balance state and is most suitable for stopping treatment; n represents the total number of all organs; f V (τ) represents the state value of the internal organs; f h Indicates the best health state of the internal organs, specifically f h =3.

[0048] Compared with the prior art, the present invention has the following beneficial effects:

[0049] The present invention uses numerical methods to describe the state values ​​of internal organs, acupoint stimulation values, and the state values ​​of qi, blood, and body fluids, and is used to demonstrate the state of internal organs, acupoints, and qi, blood, and body fluids in traditional Chinese medicine theory, and solves the problem of qualitative description in the acupuncture process in a quantitative way.

[0050] In addition to designing the functional display between the five internal organs, acupoint stimulation, qi, blood, body fluids and other elements in the acupuncture process, the present invention incorporates the influence of the eight extraordinary meridians of the human body in the acupuncture process, designs functions to describe the process, and further improves the human body model to make it simulate the acupuncture process more realistically.

[0051] The present invention designs a function method for describing the therapeutic effect of acupuncture. This function fully considers the changing trends of the internal organs during the acupuncture process, and quantitatively and intuitively calculates the optimal duration and effectiveness of acupuncture treatment from the perspectives of health level, treatment time, etc., effectively avoiding overtreatment and reducing the burden on patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0052] Figure 1 A method flow chart of a method for traditional Chinese medicine acupuncture simulation and efficacy evaluation provided by the present invention;

[0053] Figure 2 A schematic diagram of the effect of stimulating acupuncture points on various elements inside the human body according to an embodiment of the present invention;

[0054] Figure 3 Provides experimental simulation data diagrams of embodiments of the present invention;

[0055] Figure 4 The present invention provides an embodiment of the present invention. 1 is a diagram showing the changes in the states of the various organs;

[0056] Figure 5 A diagram showing changes in the states of the various organs in case 2 of an embodiment of the present invention;

[0057] Figure 6 The present invention provides a diagram of the changes in the states of the various internal organs in case 3 of an embodiment. DETAILED DESCRIPTION

[0058] The present invention is further described below in conjunction with the accompanying drawings and examples. However, the present invention can be implemented in many different ways and should not be construed as being limited to the embodiments shown; on the contrary, these embodiments provide those skilled in the art with implementation methods that meet applicable legal requirements.

[0059] Example 1: Figure 1 As shown, this embodiment provides a method for traditional Chinese medicine acupuncture simulation and efficacy evaluation, which includes the following steps:

[0060] S1: Set the value of the health status of the internal organs: according to the different health status of the internal organs, set their ranges, including deficiency, balance and excess; the value of the health status of the internal organs is set to [0.5, 5.5], specifically: [0.5, 1.5) and [1.5, 2.5) indicate that the state of the internal organs is "deficiency"; [0.5, 1.5) indicates weak deficiency; [1.5, 2.5) indicates weak deficiency; [2.5, 3.5] indicates that the state of the organ is balanced; (3.5, 4.5] and (4.5, 5.5] indicate that the state of the internal organs is "excess"; (3.5, 4.5] indicates slightly strong excess; (4.5, 5.5] indicates strong excess;

[0061] S2: Setting acupoint stimulation intensity: Determine the stimulation intensity level of acupoints, and divide it into tonifying treatment and purging treatment according to the deficiency and excess of the internal organs, and subdivide it into five levels of stimulation intensity: weak, slightly weak, normal, slightly strong and strong, represented by numbers 1 to 5; the deficiency and excess of the internal organs, the corresponding tonifying treatment and purging treatment are represented by positive integers and negative integers, and five stimulation intensities are set respectively, specifically represented as follows: the stimulation intensity range of tonifying treatment is [+1, +5], and the stimulation intensity range of purging treatment is [-5, -1];

[0062] S3: Describe the mutual influence between the internal organs: Determine the degree of influence between the internal organs in the mutual influence relationship through calculation; the calculation formula for the mutual influence (taking the liver, kidney and heart as an example) is:

[0063] f H (τ′) = g·f L (τ-1)-r·f K (τ-1)+s·f H (τ-1) (1)

[0064] Among them, f H (τ′) represents the state of the mind at time τ′, f L (τ-1), f K (τ-1) and f H (τ-1) represents the states of the liver, kidney, and heart at time τ-1, respectively; g, r, and s represent the parameters of the degree of influence of mutual growth, mutual restraint, and natural decline, respectively; where τ>τ′>τ-1;

[0065] S4: Describe the internal and external relationship of the internal organs: Describe the mutual influence between the internal organs in the internal and external relationship through calculation; the internal and external relationship of the internal organs, taking the heart and small intestine as an example, the specific calculation formula is:

[0066] f SI (τ′)=c·f H (τ′)+s·f SI (τ-1) (2)

[0067] f H (τ″)=c·f SI (τ′)+s·f H (τ′) (3)

[0068] Among them, the state values ​​of the heart and small intestine at time τ′ and τ-1 are represented by f H (τ′) and f SI (τ-1), the parameters c and s represent the influence degree and natural decay rate of the relationship between the inside and outside, respectively. In addition, τ″ needs to satisfy τ>τ″>τ′>τ-1;

[0069] S5: Describe the effect of acupoint stimulation on the health status of internal organs: Determine the direct effect of acupoint stimulation on the health status of internal organs; describe the effect of acupoint stimulation on the health status of internal organs. The specific calculation formula is:

[0070]

[0071] in, Indicates the stimulation value produced by stimulating acupoints; Indicates the state of the meridian points. When the meridian points are stimulated, When the meridian points are not stimulated, Indicates the intensity of stimulation to meridian points. is a positive integer, During purgative treatment, is a negative integer, ∈[-5,-1]; e represents the influence of different stimulus intensities on the stimulus value; Indicates the state of the internal organs; w indicates the degree of influence of the stimulus value on the internal organs; and Indicates time, and

[0072] S6: Describe the generation of Qi, blood, body fluids: Through calculation, describe the generation process of Qi, blood, body fluids under the influence of different factors; the generation of Qi, blood, body fluids is affected by the following four factors: external factors, the health status of related internal organs, the health status of the middle jiao, and the status of the other two. The specific calculation formula is:

[0073]

[0074] in, Indicates the amount of a certain substance in qi, blood, and body fluids; i_normal represents external factors; n represents the total number of related organs; h represents the value of health status, which is specifically set to 3.0; represents the sum of the state values ​​of the related organs; O represents the set of organs involved in the generation; It indicates the health ratio of these organs, reflecting their overall health status; Indicates the state value of the middle focus; Indicates the measure of the health of the middle focus; ∑f E_except_i (τ-1) represents the summary of the other two state values ​​except the current calculation; Indicates the evaluation of two other states besides the current one;

[0075] S7: Figure 2 As shown, the effect of the eight extra meridians is described: by calculation, the total effect of stimulating a certain acupoint on the eight extra meridians is determined; the effect of the eight extra meridians represents the total effect of stimulating a certain acupoint on the eight extra meridians, and the specific calculation formula is:

[0076]

[0077] in, is the stimulation value of the eight extra meridians; f TV is the stimulation value of Chong pulse;∑ k∈N f k (τ-1) is the total stimulation value of other extra meridians; N is the set of extra meridians excluding Chong, Ren and Du meridians; α and β represent constant parameters of influence weights, which represent the different influences of Chong meridian, which plays an important role in energy transport;

[0078] S8: Describe the transportation process of Qi, blood, body fluids: Describe the transportation of Qi, blood, body fluids in the body through calculation; describe that the transportation process of Qi, blood, body fluids is affected by four factors: the amount of production, the health status of related organs, the health status of the upper part of the body, and the influence of the eight extraordinary meridians. The specific calculation formula is:

[0079]

[0080] in, It indicates the amount of qi, blood, body fluids and body fluids delivered to the internal organs; v indicates the total number of destinations, specifically 10; A value indicating that the generated Qi, blood, and body fluids are evenly distributed to various destinations; Indicates the total state value of the related organs; O indicates the set of organs involved in the transportation; Indicates the health ratio of the internal organs, reflecting the health status of the related internal organs during transportation; Indicates the state value of the upper focus; It reflects the health of the upper Jiao; represents the influence of the eight extra meridians; γ represents the constant of the influence weight;

[0081] S9: Describe the process of the internal organs absorbing qi, blood, body fluids: Determine the changes in the health status of the internal organs during the process of absorbing qi, blood, body fluids; The process of describing the internal organs absorbing qi, blood, body fluids includes two parts: the consumption of the internal organs themselves and the absorption and supplementation. The specific calculation formula is:

[0082]

[0083] Among them, f V (τ) is the state value of the internal organs, and It is the amount of Qi, blood, and body fluid delivered to the internal organs. Indicates the loss of the internal organs' own state. represents absorption and supplementation, q, b and f represent the parameters of the degree of influence of qi, blood and body fluid on the internal organs, and m represents the degree of self-loss;

[0084] S10: Assess the overall health status of the internal organs and the best treatment time: Through calculation, assess the health status of each internal organ and determine the best time to stop acupuncture treatment;

[0085] The calculation formula for evaluating the overall health status of the internal organs and the optimal treatment time is:

[0086]

[0087] Among them, the best stopping time BestTime(τ) is the moment τ when σ'(τ) is closest to 0. At this time, each organ is in the best balance state and is most suitable for stopping treatment; n represents the total number of all organs; f V (τ) represents the state value of the internal organs; f h Indicates the best health state of the internal organs, specifically f h =3.

[0088] Example 2: Figure 3As shown, for the disease "color vision abnormality", TCM diagnosis of the cause is the liver and kidney, both of which are in a state of deficiency. The acupoints used for treatment are BL1, BL2, GB1, GB20, ST2, GB37, LR2, and the stimulation method is the ordinary tonification method. Substituting this method into the above formula (1)-formula (9), the changes in the internal organs shown in Table 1 (the original table is too large, only part of the table is shown) can be obtained.

[0089] Table 1 Changes of Zang-Fu organs in patients with “color vision abnormality”

[0090] Results Liver Heart Spleen Lung Kidneys τ=0 1 3 3 3 1 τ=1 1.324202 2.845251 3.06426 3.000715 1.531606 τ=2 1.59686 2.744769 3.070144 3.011304 1.895166 τ=3 1.823095 2.684159 3.045817 3.021669 2.147797 τ=4 2.012983 2.652644 3.008389 3.029798 2.326259 τ=5 2.162561 2.63936 2.967707 3.027611 2.454653 τ=6 2.28793 2.640224 2.928427 3.02031 2.547974 τ=7 2.389661 2.648521 2.896943 3.011464 2.616757 τ=8 2.470322 2.661089 2.867272 2.996619 2.668281 τ=9 2.540598 2.674308 2.843319 2.980771 2.707145 τ=10 2.599513 2.690505 2.825389 2.966544 2.736861

[0091] The table shows the changes in the status of each organ as the treatment time changes, and the numbers follow the five intervals defined above. After calculation with formula (10), we can get Figure 4 The changes in the value are used to indicate the efficacy.

[0092] Figure 4 The horizontal axis represents time, and the vertical axis represents the change of σ. Figure 4 It can be seen that when τ=41, σ is the smallest and σ' approaches 0. Therefore, in this acupuncture simulation, it can be known that acupuncture treatment can be stopped when τ=41.

[0093] The parameters are set as follows: g=0.15, r=0.05, s=0.90, c=0.10, e=0.25, w=0.01, h=3.0, v=10.

[0094] Example 3: For the disease "phantom limb pain", TCM diagnosis of the cause is the heart and liver, both in a state of deficiency, the acupoints used for treatment are GB20, GV16, EX-HN1, GV24, PC6, HT7, and the stimulation method is the ordinary tonification method. Substituting this method into the above formula (1)-formula (9), the changes in the internal organs shown in Table 2 (the original table is too large, only part of the table is shown) can be obtained.

[0095] Table 2: Changes of Zang-Fu organs in “phantom limb pain”

[0096] Results Liver Heart Spleen Lung Kidneys τ=0 1 1 3 3 3 τ=1 1.540655 1.295292 2.819593 3.07531 3.009765 τ=2 1.910002 1.546862 2.698225 3.086735 3.033497 τ=3 2.168557 1.756817 2.605188 3.064218 3.057725 τ=4 2.3529 1.93263 2.54481 3.022975 3.077387 τ=5 2.486124 2.075547 2.510341 2.976088 3.090299 τ=6 2.584993 2.190573 2.491576 2.934544 3.096568 τ=7 2.659682 2.283739 2.483933 2.894128 3.097912 τ=8 2.717373 2.359901 2.483994 2.857437 3.09518 τ=9 2.762599 2.420576 2.490886 2.823682 3.089396 τ=10 2.799897 2.474839 2.5006 2.796496 3.081219

[0097] The table shows the changes in the status of each organ as the treatment time changes, and the numbers follow the five intervals defined above. After calculation with formula (10), we can get Figure 5 The changes in the value are used to indicate the efficacy. Figure 5 The horizontal axis represents time, and the vertical axis represents the change of σ. Figure 5 It can be seen that when τ=53, σ is the smallest and σ' approaches 0. Therefore, in this acupuncture simulation, it can be known that acupuncture treatment can be stopped when τ=53.

[0098] Example 4: For the disease "red and swollen eyes", TCM diagnosis of the cause is the liver and gallbladder, both of which are in a state of deficiency. The acupoints used for treatment are GB20, BL1, EX-HN5, LR2, GB43, and the stimulation method is the ordinary purgation method. Substituting this method into the above formula (1)-formula (9), the changes in the internal organs shown in Table 3 (the original table is too large, only part of the table is shown) can be obtained.

[0099] Table 3: Changes of Zang-Fu organs in patients with red, swollen and painful eyes

[0100] Results Liver Heart Spleen Lung Kidneys τ=0 5 3 3 3 3 τ=1 4.600666 3.216102 2.931509 2.997891 2.987901 τ=2 4.311258 3.33238 2.920105 2.984201 2.98099 τ=3 4.102647 3.387862 2.955446 2.966341 2.974003 τ=4 3.945307 3.409031 2.998986 2.957183 2.964415 τ=5 3.822634 3.410103 3.041361 2.959717 2.953508 τ=6 3.720594 3.40213 3.074463 2.967197 2.942987 τ=7 3.636495 3.385582 3.104103 2.974648 2.933644 τ=8 3.564587 3.366192 3.13101 2.988242 2.925253 τ=9 3.501858 3.34548 3.151697 3.002745 2.918408 τ=10 3.445914 3.325795 3.167019 3.016767 2.913081

[0101] The table shows the changes in the status of each organ as the treatment time changes, and the numbers follow the five intervals defined above. After calculation with formula (10), we can get Figure 6 The changes in the value are used to indicate the efficacy. Figure 6 The horizontal axis represents time, and the vertical axis represents the change of σ. Figure 6 It can be seen that when τ=31, σ is the smallest and σ' approaches 0. Therefore, in this acupuncture simulation, it can be known that acupuncture treatment can be stopped when τ=31.

[0102] The examples demonstrate the effects of its application on different diseases in the process of simulating acupuncture treatment, and can accurately evaluate the state changes of various organs during the treatment process and the optimal treatment time. This method not only provides a quantitative and scientific means of acupuncture treatment simulation and evaluation, but also effectively solves the problem of incomplete consideration of human acupuncture points, organs and other elements and insufficient dynamic change evaluation in the prior art, and has significant clinical application value and promotion prospects.

[0103] The present invention proposes an acupuncture modeling method and efficacy evaluation method that can be effectively digitized and quantified, which can effectively simulate the acupuncture process and display the process of changes in the state of internal organs that cannot be directly observed in the clinical environment. This method combines traditional Chinese medicine theory with information science and technology to provide a new method for revealing the mechanism of acupuncture treatment in traditional Chinese medicine. This achievement not only helps to understand the operating mechanism of the human body, but is also expected to promote the discovery of new acupuncture therapies.

[0104] The above embodiments only express the implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention. It should be pointed out that, for those of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention.

Claims

1. A method for simulating and evaluating the efficacy of traditional Chinese medicine acupuncture, characterized in that: The method comprises the following steps: S1: Setting the health status of the internal organs: according to the different health status of the internal organs, set their ranges, including deficiency, balance and fullness; S2: Setting acupoint stimulation intensity: Determine the stimulation intensity level of acupoints, which is divided into tonifying treatment and purgative treatment according to the deficiency and excess of the internal organs, and is subdivided into five levels of stimulation intensity: weak, slightly weak, normal, slightly strong and strong, represented by numbers 1 to 5; S3: Describe the mutual generation and mutual restraint between the internal organs: Determine the degree of influence between the internal organs in the mutual generation and mutual restraint relationship through calculation; S4: Describe the internal and external relationship of the zang-fu organs: Describe the mutual influence between the zang-fu organs in the internal and external relationship through calculation; S5: Describe the effects of acupoint stimulation on the health status of internal organs: Determine the direct effects of acupoint stimulation on the health status of internal organs; S6: Describe the generation of Qi, blood, body fluids: Through calculation, describe the generation process of Qi, blood, body fluids under the influence of different factors; S7: Describe the effects of the eight extra meridians: Determine the total effect of stimulating a certain acupoint on the eight extra meridians through calculation; S8: Describe the transportation process of Qi, blood, body fluids: Describe the transportation of Qi, blood, body fluids in the body through calculations; S9: Describe the process of the internal organs absorbing qi, blood, body fluids: Determine the changes in the health status of the internal organs during the process of absorbing qi, blood, body fluids; S10: Assess the overall health status of the internal organs and the optimal treatment time: Through calculation, assess the health status of each internal organ and determine the optimal time to stop acupuncture treatment.

2. The method for traditional Chinese medicine acupuncture simulation and efficacy evaluation according to claim 1, characterized in that: In step S1, the value of the health status of the internal organs is set to [0.5, 5.5], specifically: [0.5, 1.5) and [1.5, 2.5) indicate that the state of the internal organs is "weak"; [0.5, 1.5) indicates weak in deficiency; [1.5, 2.5) indicates weak in deficiency; [2.5, 3.5] indicates that the organ state is in a balanced state; (3.5, 4.5] and (4.5, 5.5] indicate that the state of the internal organs is "full"; (3.5, 4.5] indicates slightly strong in full; (4.5, 5.5] indicates strong in full. The method for simulating and evaluating the therapeutic effect of acupuncture and moxibustion according to claim 1 is characterized in that: the deficiency and excess of the internal organs in step S2, the corresponding tonifying treatment and purgative treatment are represented by positive integers and negative integers, and five stimulation intensities are set respectively, specifically represented as: the stimulation intensity range of the tonifying treatment is [+1, +5], and the stimulation intensity range of the purgative treatment is [-5, -1].

3. The method for traditional Chinese medicine acupuncture simulation and efficacy evaluation according to claim 1, characterized in that: The calculation formula of the mutual promotion and mutual restraint influence (taking the liver, kidney and heart as an example) in step S3 is: f H (τ′)=g·f L (τ-1)-r·f K (τ-1)+s·f H (t-1) (1) Among them, f H (τ′) represents the state of the mind at time τ′, f L (τ-1), f K (τ-1) and f H (τ-1) represents the states of the liver, kidney and heart at the time τ-1 respectively, g, r and s represent the parameters of the influence of mutual generation, mutual restraint and natural decay respectively, among which, τ>τ′>τ-1.

4. The method for traditional Chinese medicine acupuncture simulation and efficacy evaluation according to claim 1, characterized in that: The relationship between the internal and external organs in step S4 is calculated by taking the heart and small intestine as an example: f SI (τ′)=c·f H (τ′)+s·f SI (t-1) (2) f H (τ″)=c·f SI (τ′)+s·f H (t′) (3) Among them, the state values ​​of the heart and small intestine at time τ′ and τ-1 are represented by f H (τ′) and f SI (τ-1), the parameters c and s represent the influence degree and natural decay rate of the relationship between the inside and outside, respectively. In addition, τ″ needs to satisfy τ>τ″>τ′>τ-1.

5. The method for traditional Chinese medicine acupuncture simulation and efficacy evaluation according to claim 1, characterized in that: The step S5 describes the effect of acupoint stimulation on the health status of internal organs, and the specific calculation formula is: in, Indicates the stimulation value produced by stimulating acupoints; Indicates the state of the meridian points. When the meridian points are stimulated, When the meridian points are not stimulated, Indicates the intensity of stimulation to meridian points. is a positive integer, During purgative treatment, is a negative integer, ∈[-5, -1]; e represents the influence of different stimulus intensities on the stimulus value; Indicates the state of the internal organs; w indicates the degree of influence of the stimulus value on the internal organs; and Indicates time, and 6. The method for simulating and evaluating the efficacy of acupuncture and moxibustion according to claim 1, characterized in that: The generation of qi, blood, and body fluids in step S6 is affected by the following four factors: external factors, the health status of related internal organs, the health status of the middle jiao, and the status of the other two. The specific calculation formula is: in, Indicates the amount of a certain substance in qi, blood, and body fluids; i_normal represents external factors; n represents the total number of related organs; h represents the value of health status, which is specifically set to 3.0; represents the sum of the state values ​​of the related organs; O represents the set of organs involved in the generation; It indicates the health ratio of these organs, reflecting their overall health status; Indicates the state value of the middle focus; Indicates the measure of the health of the middle focus; ∑f E_except_i (τ-1) represents the summary of the other two state values ​​except the current calculation; Indicates the evaluation of two other states besides the current one.

7. The method for simulating and evaluating the efficacy of acupuncture in traditional Chinese medicine according to claim 1, characterized in that: The effect of the eight extra meridians in step S7 represents the total effect of stimulating a certain acupoint on the eight extra meridians, and the specific calculation formula is: in, is the stimulation value of the eight extra meridians; f TV is the stimulation value of Chong pulse;∑ k∈N f k (τ-1) is the total stimulation value of other extraordinary meridians; N is the set of extraordinary meridians excluding Chong, Ren and Du meridians; α and β represent constant parameters affecting the weights, which represent the different influences of Chong meridian, which plays an important role in energy transport.

8. The method for simulating and evaluating the efficacy of acupuncture and moxibustion according to claim 1, characterized in that: Step S8 describes that the transport process of qi, blood, and body fluid is affected by four factors: the amount of generation, the health status of related internal organs, the health status of the upper part of the body, and the influence of the eight extraordinary meridians. The specific calculation formula is: in, It indicates the amount of qi, blood, body fluids and body fluids delivered to the internal organs; v indicates the total number of destinations, specifically 10; A value indicating that the generated Qi, blood, and body fluids are evenly distributed to various destinations; Indicates the total state value of the related organs; O indicates the set of organs involved in the transportation; Indicates the health ratio of the internal organs, reflecting the health status of the related internal organs during transportation; Indicates the status value of the upper focus; It reflects the health of the upper Jiao; represents the influence of the eight extra meridians; γ represents the constant of the influence weight.

9. The method for simulating and evaluating the efficacy of acupuncture in traditional Chinese medicine according to claim 1, characterized in that: The process of the internal organs absorbing qi, blood and body fluids described in step S9 includes two parts: the consumption of the internal organs themselves and the absorption and replenishment. The specific calculation formula is: Among them, fV(τ) is the state value of the internal organs, and It is the amount of Qi, blood, and body fluid delivered to the internal organs. Indicates the loss of the internal organs' own state. represents absorption and supplementation, q, b and f represent the parameters of the influence of qi, blood, body fluids and zang-fu organs, and m represents the degree of self-loss.

10. The method of traditional Chinese medicine acupuncture simulation and efficacy evaluation according to claim 1, characterized in that: The calculation formula for evaluating the overall health status of the internal organs and the optimal treatment time in step S10 is: Among them, the best stopping time BestTime(τ) is the moment τ when σ′(τ) is closest to 0. At this time, each organ is in the best balance state and is most suitable for stopping treatment; n represents the total number of all organs; fV(τ) represents the state value of the organs; f h Indicates the best health state of the internal organs, specifically f h =3.

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