Melasyl formula for powerfully whitening and improving skin color

Abstract

The invention relates to the technical field of skin care products, and particularly discloses a formula of melsyl for powerfully whitening and improving skin color, which is composed of the following components: phenylethyl resorcinol, 2-mercaptonicotinoyl glycine, acetylchitosamine, nicotinamide, water, glycerol, an emulsifier, squalene, sodium hyaluronate, a preservative and a proper amount of a pH regulator. The Melasyl in the formula serves as a core whitening component, generation and transport of melanin are inhibited through covalent binding of sulfydryl of the Melasyl and a melanin precursor, so that color spots and uneven skin color are effectively reduced, phenethyl resorcinol is combined, the activity of tyrosinase is strongly inhibited, generation of melanin is reduced, and the whitening effect is achieved.

Description

Technical Field

[0001] The invention belongs to the technical field of skin care products, and in particular relates to a melasyl formula for strongly whitening and improving skin color. Background Art

[0002] Skin whitening and improving uneven skin tone have become urgent needs of more and more consumers. Traditional whitening products often focus on a single ingredient or a single mechanism of action, which makes it difficult to meet consumers' needs for efficient and comprehensive whitening. At the same time, some whitening products may have problems such as high irritation and unstable effects, which bring bad experience to consumers.

[0003] In order to solve the above problems, people have developed a variety of new whitening ingredients and technologies. Among them, Melasyl, as an emerging whitening ingredient, has attracted much attention due to its unique whitening mechanism and good skin compatibility. However, the whitening effect of a single ingredient is limited and needs to work synergistically with other ingredients to achieve the best effect. Summary of the invention

[0004] The object of the present invention is to provide a melasyl formula for strong whitening and improving skin color, so as to solve the problems raised in the above background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A melasyl formula for strong whitening and skin tone improvement, comprising the following components in the following weight ratios:

[0007] Phenethyl resorcinol 0.5-1%, 2-mercaptonicotinoylglycine 0.2-0.5%, acetyl glucosamine 0.5-1.5%, niacinamide 1.5-3%, water 60-70%, glycerin 3-7%, emulsifier 3-5%, squalene 2-4%, sodium hyaluronate 0.3-0.7%, preservative 0.5-1.5%, pH adjuster as needed.

[0008] Preferably, the melasyl formula for strong whitening and skin tone improvement is prepared by the following preparation method:

[0009] S1. Material preparation: Pour water and glycerin into a mixing container, use a heating device to heat the water phase to 65°C, and stir continuously to form a water phase; in another mixing container, add emulsifier and squalene, heat to 65°C, and continue stirring until all ingredients are completely melted to form a uniform oil phase;

[0010] S2. Mixing and cooling: slowly and evenly pour the oil phase into the water phase while stirring rapidly with a stirrer until a stable and uniform emulsion is formed, then stop heating, continue stirring, and allow the mixture to cool naturally to below 40°C;

[0011] S3, adding and adjusting: when the temperature drops below 40°C, add phenylethyl resorcinol, 2-mercaptonicotinoyl glycine, acetyl glucosamine and nicotinamide in sequence, stirring evenly after each addition to ensure that the active ingredients are evenly dispersed, then add the preservative to the mixture, continue stirring until completely dissolved, and finally add citric acid dropwise until the pH value is adjusted to the range of 4.5-5.5 to obtain a melasyl formula;

[0012] S4. Processing: Filter the prepared melasyl formulation through a sterile filter to remove impurities.

[0013] Preferably, the emulsifier is emulsifying wax, the preservative is one or a mixture of phenoxyethanol and ethylhexylglycerin, and the pH regulator is citric acid.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] (1) 2-Mercaptonicotinylglycine in the formula is the core whitening ingredient. Through the covalent bonding of its thiol group with melanin precursors, it inhibits the production and transport of melanin, thereby effectively reducing spots and uneven skin tone. Combined with phenylethyl resorcinol, it strongly inhibits the activity of tyrosinase and reduces the production of melanin, thereby achieving a whitening effect.

[0016] (2) Through the interaction between acetyl glucosamine and niacinamide, it has multiple functions such as moisturizing, strengthening the skin barrier, reducing fine lines and improving skin pigmentation. By inhibiting the activity of tyrosinase and reducing the synthesis of melanin, it helps to improve uneven skin tone and brighten the skin tone. It can also moisturize, control oil and resist aging.

[0017] (3) Through the cooperation of glycerin, squalene and sodium hyaluronate, a thin film can be formed on the skin to help lock in moisture and prevent water loss. At the same time, it also has anti-inflammatory and skin-nourishing effects, making the skin feel softer and more moisturized, and can enhance the skin's moisturizing ability while providing a light and non-greasy skin feel. It can also absorb and retain a large amount of water molecules to keep the skin moisturized and smooth. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a flow chart of the present invention. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0020] Embodiment 1:

[0021] See also Figure 1 As shown, a melasyl formula for strong whitening and skin tone improvement is composed of the following components in weight ratio:

[0022] Phenylethylresorcinol 0.5%, 2-mercaptonicotinoylglycine 0.3%, acetyl glucosamine 1.0%, niacinamide 2.0%, water 65.0%, glycerin 5.0%, emulsifier 4.0%, squalene 3.0%, sodium hyaluronate 0.5%, preservative 1.0%, pH adjuster as needed;

[0023] A melasyl formula for effectively whitening and improving skin color is prepared by the following preparation method:

[0024] S1. Material preparation: Pour water and glycerin into a mixing container, use a heating device to heat the water phase to 65°C, and stir continuously to form a water phase; in another mixing container, add emulsifier and squalene, heat to 65°C, and continue stirring until all ingredients are completely melted to form a uniform oil phase;

[0025] S2. Mixing and cooling: slowly and evenly pour the oil phase into the water phase while stirring rapidly with a stirrer until a stable and uniform emulsion is formed, then stop heating, continue stirring, and allow the mixture to cool naturally to below 40°C;

[0026] S3, adding and adjusting: when the temperature drops below 40°C, add phenylethyl resorcinol, 2-mercaptonicotinoyl glycine, acetyl glucosamine and nicotinamide in sequence, stirring evenly after each addition to ensure that the active ingredients are evenly dispersed, then add the preservative to the mixture, continue stirring until completely dissolved, and finally add citric acid dropwise until the pH value is adjusted to the range of 4.5-5.5 to obtain a melasyl formula;

[0027] S4. Processing: Filter the prepared melasyl formulation through a sterile filter to remove impurities.

[0028] In one embodiment of the present invention, the emulsifier is emulsifying wax, the preservative is one or a mixture of phenoxyethanol and ethylhexylglycerin, and the pH regulator is citric acid.

[0029] Embodiment 2:

[0030] Phenylethylresorcinol 0.7%, 2-mercaptonicotinoylglycine 0.4%, acetyl glucosamine 0.3%, niacinamide 1.3%, water 65.0%, glycerin 6%, emulsifier 3%, squalene 2%, sodium hyaluronate 0.6%, preservative 1.3%, pH adjuster as needed;

[0031] The rest is the same as that of the first embodiment and will not be described in detail here.

[0032] Application test case

[0033] 30 female volunteers aged between 25 and 45 years old with uneven skin color and pigmentation were selected. The volunteers were randomly divided into three groups, with 10 people in each group. The first two groups used the products prepared in Example 1 and Example 2, respectively, and the third group used a representative existing whitening product on the market as a control. The volunteers were required to apply an appropriate amount of the product evenly on the face after cleansing every morning and evening, and gently massage until completely absorbed, and use it for 8 consecutive weeks;

[0034] Whitening effect evaluation:

[0035] Before use, after 4 weeks of use, and after 8 weeks of use, the volunteers' facial skin color was measured using a skin colorimeter, and the L value (brightness), a value (red-green value), and b* value (yellow-blue value) were recorded to evaluate the changes in skin color. By comparing the skin color data before and after use, the color difference ΔE was calculated to evaluate the whitening effect. The smaller the ΔE value, the more obvious the whitening effect, as shown in the following table:

[0036]

[0037] In this experiment, the whitening effects of both Example 1 and Example 2 are better than those of the prior art products, among which the effect of Example 1 is the most significant;

[0038] Skin feel assessment:

[0039] After 4 weeks and 8 weeks of use, the volunteers were asked to rate the skin feel of the product, including freshness, moisturizing, absorption speed and greasiness. The rating was based on a 5-point system, with 1 point indicating very poor and 5 points indicating very good. The details are as follows:

[0040]

[0041] The skin feel scores of the four products were all high, but Example 1 performed best in terms of freshness and absorption speed, while Example 2 also performed well in terms of moisturizing;

[0042] In summary, the Melasyl formula for strong whitening and skin color improvement prepared in Example 1 and Example 2 is superior to the existing products in whitening effect, and has good skin feel, stability and safety. Among them, the whitening effect of Example 1 is the most outstanding.

[0043] Among the above components:

[0044] Phenylethyl resorcinol can penetrate deep into the skin and effectively inhibit the activity of tyrosinase, thereby reducing the production of melanin and helping the skin regain brightness and evenness;

[0045] 2-Mercaptonicotinoylglycine forms a covalent bond with melanin precursors through its thiol structure, effectively inhibiting the production and transport of melanin, further reducing spots and improving skin tone uniformity;

[0046] Acetyl glucosamine not only has moisturizing effects, but also strengthens the skin barrier, reduces fine lines, and helps improve skin pigmentation, making the skin smoother and more delicate;

[0047] Niacinamide can whiten the skin, moisturize, control oil, and resist aging, thus comprehensively improving skin quality;

[0048] Glycerin can form a protective film on the skin surface, lock in moisture, prevent moisture loss, and keep the skin hydrated;

[0049] Emulsifiers are responsible for evenly mixing oily and aqueous ingredients to form a stable emulsion, ensuring the stability of the formula and a good skin feel;

[0050] Squalene has excellent moisturizing and antioxidant properties, which can strengthen the skin's moisture barrier and make the skin softer and smoother;

[0051] Sodium hyaluronate can absorb and retain a large amount of water molecules, providing lasting moisture and smoothness to the skin;

[0052] Preservatives are used to prevent the formula from being contaminated by microorganisms during use and ensure the safety and stability of the product;

[0053] pH adjusters are used to adjust the pH value of the formula to make it more suitable for the physiological environment of the skin, helping to maintain the stability of the formula and improve its effectiveness.

[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A melasyl formula for strong whitening and skin tone improvement, characterized in that: The invention is composed of the following components in weight ratio: 0.5-1% of phenylethylresorcinol, 0.2-0.5% of 2-mercaptonicotinoylglycine, 0.5-1.5% of acetyl glucosamine, 1.5-3% of nicotinamide, 60-70% of water, 3-7% of glycerol, 3-5% of emulsifier, 2-4% of squalene, 0.3-0.7% of sodium hyaluronate, 0.5-1.5% of preservative and appropriate amount of pH regulator.

2. The melasyl formula for strong whitening and skin color improvement according to claim 1, characterized in that: The melasyl formula for strong whitening and improving skin color is prepared by the following preparation method: S1. Material preparation: Pour water and glycerin into a mixing container, use a heating device to heat the water phase to 65°C, and stir continuously to form a water phase; in another mixing container, add emulsifier and squalene, heat to 65°C, and continue stirring until all ingredients are completely melted to form a uniform oil phase; S2. Mixing and cooling: slowly and evenly pour the oil phase into the water phase while stirring rapidly with a stirrer until a stable and uniform emulsion is formed, then stop heating, continue stirring, and allow the mixture to cool naturally to below 40°C; S3, adding and adjusting: when the temperature drops below 40°C, add phenylethyl resorcinol, 2-mercaptonicotinoyl glycine, acetyl glucosamine and nicotinamide in sequence, stirring evenly after each addition to ensure that the active ingredients are evenly dispersed, then add the preservative to the mixture, continue stirring until completely dissolved, and finally add citric acid dropwise until the pH value is adjusted to the range of 4.5-5.5 to obtain a melasyl formula; S4. Processing: Filter the prepared melasyl formulation through a sterile filter to remove impurities.

3. The melasyl formula for strong whitening and skin color improvement according to claim 1, characterized in that: The emulsifier is emulsifying wax, the preservative is one or a mixture of phenoxyethanol and ethylhexylglycerin, and the pH regulator is citric acid.

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