AI-based hair follicle drug screening and detecting device

Abstract

The invention discloses an AI-based hair follicle drug screening and detecting device, and belongs to the field of drug screening and detecting. The AI-based hair follicle drug screening and detecting device comprises a storage pool, an optical detection module and transmission pipes on the two sides of the storage pool, a bidirectional threaded rod is arranged at the upper end of the storage pool, and first transmission frames are arranged on the two sides of the exterior of the optical detection module. The medicine screening device solves the problems that in the screening process of an existing medicine screening device, rotation and connection between a flow cell and a pipe sleeve are conducted at the same time, so that the pipe sleeve deforms and is damaged, the sealing performance of equipment is affected, and the service life of the equipment is shortened. A transmission block rotates to drive a two-way threaded rod to rotate so that a transmission pipe and a connecting pipe can be disconnected, a gear and the transmission rod are driven to rotate along with continuous rotation of the transmission block, a storage pool can be overturned through rotation of the transmission rod to achieve pouring and cleaning of chemicals, and rotation of the storage pool and pulling out of the transmission pipe are divided into two steps; the transmission pipe is prevented from being damaged.

Description

Technical Field

[0001] The present invention relates to the field of drug screening and detection, and in particular to an AI-based hair follicle drug screening and detection device. Background Art

[0002] Drug screening detection device is a device specially used to quickly and accurately screen drug molecules with potential pharmacological activity or specific biological effects from a large number of candidate compounds. It integrates advanced chemistry, biology, informatics and automation technologies, can simulate the drug action environment in the body, and conduct high-throughput and high-efficiency evaluation of compounds, thereby accelerating the process of new drug research and development, reducing research and development costs, and improving the success rate of new drug discovery;

[0003] A Chinese patent with publication number CN109916815B discloses a drug screening device based on SPR, including a rotating drum frame, which is rotatably connected to a fixed shaft, and the rotating drum frame is distributed with circumferentially distributed nested mounting grooves, and flow cells are nested in the nested mounting grooves. The flow cells can be replaced by a rotating drum frame and a groove wheel mechanism for fixing the circumferentially distributed flow cells, thereby achieving replacement of targeted molecules and improving the efficiency of drug screening. In addition, a left connecting card connector, a right connecting card connector, a sliding block and a bidirectional screw rod are provided to facilitate connection and disconnection of the flow cell and the connecting card connector, and facilitate synchronous replacement of the flow cell.

[0004] During the screening process, the drug screening device of the above patent will cause the circulation pool to be connected to the joint through transmission, and the rotating drum frame will also drive the circulation pool to rotate. The simultaneous rotation and connection between the circulation pool and the tube sleeve will cause the sleeve to deform and be damaged, affecting the sealing of the equipment and reducing the service life of the equipment. Summary of the invention

[0005] The purpose of the present invention is to provide an AI-based hair follicle drug screening and detection device, which first drives the two-way threaded rod to rotate by the rotation of the transmission block to disconnect the transmission tube from the connecting tube. As the transmission block continues to rotate, the gear and the transmission rod are driven to rotate. The rotation of the transmission rod can flip the storage pool to achieve the pouring and cleaning of the medicine. The rotation of the storage pool and the extraction of the transmission tube are divided into two steps, which avoids damage to the transmission tube and solves the problems raised in the above-mentioned background technology.

[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an AI-based hair follicle drug screening and detection device, comprising a storage tank, an optical detection module and transmission tubes on both sides of the storage tank, wherein a bidirectional threaded rod is arranged at the upper end of the storage tank, and the counterclockwise rotation of the bidirectional threaded rod can simultaneously generate relative motion with the interior of a second transmission frame, and the second transmission frame is restricted by the upper end of the interior of the hair follicle drug screening and detection device housing, so that the second transmission frame is converted from rotational motion to lateral linear motion, and the rotation of the bidirectional threaded rod can simultaneously drive the two transmission tubes to be pulled out of the connecting tube, and at the same time, the clockwise rotation of the bidirectional threaded rod can reset the transmission tube and make it stuck outside the connecting tube. The optical detection module is provided with a first transmission frame on both sides of the outside of the optical detection module, and the bidirectional threaded rod is driven by a transmission group to move the transmission tube away from the storage tank and then the first transmission frame rotates. The transmission group includes a transmission rod, a gear, a transmission block, a tooth groove and a synchronous belt for connecting the gear and the transmission rod. The tooth groove is arranged on half a circle of the transmission block. By reducing the tooth groove arranged on half a circle, the transmission block will not drive the gear to rotate immediately after it is started, so that the transmission block will first drive the transmission tube to adjust its position after the output, and the tooth groove is meshed with the gear.

[0007] Preferably, the transmission block is welded to one side of the bidirectional threaded rod, and the transmission rod is welded to one side of the first transmission frame. When the storage tank is located at the upper end of the optical detection module, the external tooth groove of the transmission block is located on one side of the upper end of the gear. The transmission block rotates to make the tooth groove contact the gear and then drives the gear to rotate clockwise. The storage tank can be driven to flip by adjusting the rotation of the transmission block. During the flipping of the storage tank, the pharmaceutical material used for detection inside the storage tank can be dumped. After the storage tank rotates and finally flips, it can be cleaned. Subsequently, the rotation direction of the transmission block is adjusted so that the transmission block rotates clockwise. The transmission block will first drive the storage tank to flip and reset. Since the transmission block is only provided with tooth grooves in half a circle, the clockwise rotation of the transmission block will first drive the transmission block to flip. After flipping, due to the confirmation of the tooth groove, the transmission block will not drive the storage tank to flip. With the continuous rotation of the transmission block, the transmission tube is reset and inserted into the connecting tube again.

[0008] Preferably, the rotation of the bidirectional threaded rod drives the transmission tube to move laterally by cooperating with the thread of the second transmission frame, and the two sides of the storage tank are sealed and connected to the transmission tube through the connecting tube. The lateral movement of the second transmission frame can adjust the connection state between the transmission tube and the connecting tube. The outside of the transmission tube is fixed to the lower end of the inside of the second transmission frame. After the position of the second transmission frame is adjusted laterally, the second transmission frame can pull the transmission tube out from the outside of the connecting tube, and similarly, the transmission tube can be clamped on the outside of the connecting tube through the second transmission frame.

[0009] Preferably, a connecting block with the same weight as the storage pool is provided at the lower end of the optical detection module, and the first transmission frame is fixed to the outer walls of the storage pool and the connecting block by bolts respectively. The connecting block can offset the weight of the storage pool to prevent the transmission rod from easily rotating due to the weight of the storage pool and to prevent the storage pool from having poor stability. The storage pool fixed by bolts can be convenient for the user to replace the storage pool. With long-term use, the user can unfold the outer wall of the hair follicle drug screening detection device to expose the storage pool, and the storage pool can be manually disassembled and replaced later.

[0010] Preferably, a lower storage frame is provided at the lower end of the connecting block, and an adjustable spray assembly is provided on the lower storage frame toward the storage pool, and a hot air blower is provided on one side of the upper end of the adjustable spray assembly, so that the connecting block can be dried by the hot air blower to prevent the damp connecting block from affecting the subsequent placement of medicines, and the adjustable spray assembly can be supported by the lower storage frame, and the support can also enable the adjustable spray assembly to be positioned to spray pure water toward the storage pool, so that the pure water can directly and comprehensively clean the storage pool, and comprehensive cleaning can facilitate the subsequent screening and detection of multiple medicines.

[0011] Preferably, a fixed plate with an exhaust hole is provided on the side of the hot air blower facing the adjustable spray assembly, the exhaust hole faces the storage pool and is sealed and connected to the hot air blower, the storage pool is flipped to the upper end of the fixed plate by being driven by the transmission group, and the exhaust hole faces the flipped storage pool to directly exhaust the air, so as to dry the cleaned storage pool, and the fixed plate can slide laterally as it is pushed, move laterally and wrap around the upper end of the adjustable spray assembly, and cover the flipped storage pool while wrapping around the upper end of the adjustable spray assembly, so that the high-temperature gas discharged from the inside of the fixed plate can quickly and closely contact the cleaning position inside the storage pool, and can directly and efficiently dry the storage pool after cleaning.

[0012] Preferably, the hot air blower is driven by a one-way threaded rod to adjust its lateral position. The rotation of the one-way threaded rod can enable the cleaned storage pool to rotate only after the housing of the hair follicle drug screening detection device restricts the hot air blower to adjust the fixed disk, thereby preventing the protruding fixed disk from affecting the normal rotation of the storage pool.

[0013] Preferably, drainage holes are provided on both sides of the front end of the storage tank. The reserved drainage holes allow the medicine to be discharged from the drainage holes during the rotation when the storage tank is rotated and the orientation is adjusted. The medicine does not need to be discharged after the storage tank is turned over, thereby avoiding splashing caused by the unified discharge of all medicines and avoiding the medicine from being discharged into the interior of the adjustable spray assembly, thereby affecting the subsequent discharge of pure water from the adjustable spray assembly.

[0014] Preferably, the horizontal plane of the medicine transmitted to the storage tank by the transmission tube is not higher than the drainage hole, and the medicine transmitted by the transmission tube is located at the lower end of the drainage hole to prevent the medicine from flowing out directly from the drainage hole. The drainage hole can allow the medicine body inside the storage tank to be discharged in advance during the flipping of the storage tank, so that the medicine can be poured into the lower storage frame in advance.

[0015] Preferably, the adjustable spray assembly includes: an outer ring bracket and an inner ring bracket, the outer ring bracket and the inner ring bracket are connected by a plurality of groups of connecting brackets, a plurality of groups of inner ring fan blades are installed in the inner ring bracket, a plurality of groups of inner ring fan blades are installed between the outer ring bracket and the inner ring bracket, a driving motor is fixedly arranged on the outer wall of the outer ring bracket, a driving gear is fixedly sleeved on the output shaft of the driving motor, an annular driving member is movably sleeved on the outer wall of the outer ring bracket, and the annular driving member and the outer ring bracket are connected by threads, a plurality of groups of meshing teeth are arranged on the outer wall of the annular driving member, and the driving gear is meshed with the plurality of groups of meshing teeth, a plurality of groups of supporting members are fixedly arranged around the outer wall of the outer ring bracket, and the same rotating bearing is installed in each group of supporting members, and the first rotating connecting member is rotated by The cam is connected to the outer ring bracket by the first rotating connection piece, and the first rotating connection piece extends from the rotating bearing 1 at one end and is fixedly connected to the driving connecting rod, and the other end of the first rotating connection piece is fixedly connected to the outer ring fan blades, and the end of the driving connecting rod away from the rotating bearing 1 is movably connected to the outer wall of the annular driving piece. The inner ring bracket is provided with a plurality of groups of supporting grooves and through holes, and each group of supporting grooves and through holes are coaxially arranged, and the same rotating bearing 2 is installed in each group of supporting grooves, and the second rotating connection piece is movably connected to the inner ring bracket through the rotating bearing 2, and the second rotating connection piece extends from the rotating bearing 2 at one end and is fixedly connected to the outer ring fan blades, and the other end of the second rotating connection piece passes through the through hole and is fixedly connected to the inner ring fan blades, and the outer ring fan blades and inner ring fan blades located on the same axis are perpendicular to each other.

[0016] Preferably, it further comprises: a tension sensor, arranged on the synchronous belt, for monitoring the tension level of the synchronous belt when in use;

[0017] A laser centering sensor, which is arranged on the inner wall of the detection device housing and is located on the same axis as the synchronous belt, and is used to monitor the offset of the synchronous belt when it is in use;

[0018] A temperature sensor is arranged in the housing of the detection device and is used to monitor the ambient temperature of the synchronous belt when it is working;

[0019] A rotation speed sensor 1, arranged on the transmission rod, for monitoring the rotation speed of the transmission rod;

[0020] A second speed sensor is arranged on the transmission block and is used to monitor the speed of the transmission block;

[0021] A timer, arranged on the outer surface of the detection device, for monitoring the use time of the screening device;

[0022] An alarm, wherein the alarm is arranged on the outer surface of the detection device;

[0023] A controller, which is arranged on the outer surface of the detection device housing, and is electrically connected to the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, the timer, and the alarm respectively. The controller controls the alarm to work based on the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, and the timer, including:

[0024] Step 1: The controller calculates the strain state coefficient of the synchronous belt during use based on the tension sensor, the laser centering sensor, the timer, the speed sensor 1, the speed sensor 2 and formula (1):

[0025]

[0026] Wherein, X is the strain state coefficient of the synchronous belt during use, F1 is the detection value of the tension sensor, F2 is the preset maximum tension that the synchronous belt can withstand, n1 is the detection value of the speed sensor 1, n2 is the detection value of the speed sensor 2, L1 is the detection value of the laser centering sensor, R1 is the radius of the transmission rod, R2 is the radius of the motor output shaft that drives the transmission block to rotate, s is the detection value of the timer, μ1 is the friction coefficient of the synchronous belt, θ is the Poisson's ratio of the synchronous belt material, S1 is the contact surface area of ​​the synchronous belt and the transmission rod, E is the shear modulus of the synchronous belt, and ln is the natural logarithm with e as the base;

[0027] Step 2: Based on step 1, the controller calculates the life index of the synchronous belt based on the temperature sensor and formula (II):

[0028]

[0029] Wherein, Y is the life index of the synchronous belt, is the preset maximum wear amount of the synchronous belt, T1 is the detection value of the temperature sensor, T2 is the current ambient temperature, K is the product of the accuracy of the tension sensor, laser centering sensor, temperature sensor, speed sensor 1, speed sensor 2, and timer, Δ1 is the preset damage coefficient of the synchronous belt, and e is a natural constant with a value of 2.72;

[0030] Step three: the controller compares the life index of the synchronous belt calculated in step two with a preset life index. When the life index of the synchronous belt calculated in step two is less than the preset life index, the controller controls the alarm to issue an alarm prompt.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] 1. In the process of the transmission block of the present invention rotating and the transmission tube being pulled out from both sides of the storage tank driven by the bidirectional threaded rod, there is no tooth groove distributed around the outer side of the transmission block and cannot drive the gear to rotate, and as the transmission block continues to rotate counterclockwise, the transmission block will drive the gear to rotate through the tooth groove, and the rotation of the gear will drive the storage tank from which the transmission tube is pulled out to rotate after being transmitted by the synchronous belt and the transmission rod. After being driven and rotated, the transmission block can realize the pulling out of the transmission tube and the rotation of the storage tank in turn, avoiding the damage of the connection position between the transmission tube and the connecting tube caused by the synchronous operation, and after the transmission block rotates 360 degrees counterclockwise at a time to realize the pulling out of the transmission tube and the flipping of the storage tank in turn, the transmission block can rotate clockwise to realize the flipping of the storage tank and then insert the transmission tube into the connecting tubes on both sides of the storage tank, which is simple to operate and can increase the service life of the equipment, avoiding the need to frequently replace the connection position between the transmission tube and the connecting tube.

[0033] 2. During the flipping process of the storage tank of the present invention, the liquid at the lower end of the storage tank will flow toward the drain hole after flipping, and will be discharged to the outside of the storage tank through the drain hole and then fall into the lower receiving frame. The medicine inside the storage tank can be actively dumped by flipping the storage tank, thereby improving the cleaning effect of the storage tank and preventing the dumped medicine from filling the outside of the adjustable spray assembly. On the other hand, as the storage tank rotates, the storage tank can be aligned with the adjustable spray assembly, and the liquid sprayed from the adjustable spray assembly will actively clean the storage tank. After cleaning, the hot air blower is started to discharge high-temperature gas from the exhaust hole, actively drying the inside of the storage tank, and efficiently and quickly cleaning the storage tank, which is convenient for the subsequent input, screening and detection of medicines. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 It is the front view of the overall external structure of the present invention;

[0035] Figure 2 A side view showing the position relationship of the fixed disk of the present invention;

[0036] Figure 3 It is a schematic diagram of the gear transmission structure of the present invention;

[0037] Figure 4 It is a schematic diagram of the position relationship of the tooth grooves of the present invention;

[0038] Figure 5 An exploded view of the connection relationship between the transmission pipe and the storage tank of the present invention;

[0039] Figure 6 It is a schematic diagram of the transmission structure of the storage tank and the connecting block of the present invention;

[0040] Figure 7The adjustable spray assembly structure of the present invention is schematically shown in FIG. Figure 1 ;

[0041] Figure 8 The adjustable spray assembly structure of the present invention is schematically shown in FIG. Figure 2 ;

[0042] Fig. 9 The adjustable spray assembly structure of the present invention is schematically shown in FIG. Figure 3 ;

[0043] In the figure: 1, first transmission frame; 2, storage tank; 3, lower storage frame; 4, adjustable spray assembly; 5, transmission rod; 6, gear; 7, transmission block; 8, two-way threaded rod; 9, second transmission frame; 10, transmission pipe; 11, fixed plate; 12, hot air blower; 13, one-way threaded rod; 14, drainage hole; 16, exhaust hole; 18, tooth groove; 21, connecting pipe; 22, connecting shaft; 23, connecting block; 24, synchronous belt; 25 , outer ring bracket; 26, inner ring bracket; 27, inner ring fan blades; 28, connecting bracket; 29, outer ring fan blades; 30, waterproof shell; 31, driving motor; 32, driving gear; 33, annular driving member; 34, meshing teeth; 35, rotating bearing one; 36, driving connecting rod; 37, first rotating connecting member; 38, supporting member; 39, second rotating connecting member; 40, rotating bearing two; 41, supporting groove; 42, through hole. DETAILED DESCRIPTION

[0044] The present invention is further described below in conjunction with specific embodiments.

[0045] Example 1

[0046] like Figure 1 As shown, the AI-based hair follicle drug screening and detection device of this embodiment includes a storage pool 2, transmission tubes 10 for transmitting drugs on both sides of the storage pool 2, and a transmission group for driving the storage pool 2 to rotate. The hair follicle drug liquid will be stored in the storage pool 2 after being extracted during detection. The optical detection module set at the lower end of the storage pool 2 will detect the hair follicle drug liquid and calculate the data through the built-in AI module of the hair follicle drug screening and detection device, calculate and perform curve fitting, and judge the effectiveness of the drug;

[0047] Both sides of the storage tank 2 are provided with barrel-shaped structures for storing medicines. The medicines to be tested can be poured into the barrel-shaped structures in advance, and the medicines inside the barrel-shaped structures can be directly extracted to transport the medicines to the storage tank 2. The medicines on both sides can be proportioned according to the amount extracted, so as to realize more proportioned medicine tests, which is more helpful for AI calculation and elimination of schemes that do not need to be tested. The barrel-shaped structures on both sides can also be used alternately. After the user has used the medicine in one of the barrel-shaped structures, when cleaning the barrel-shaped structure, the medicine can be directly loaded into the other barrel-shaped structure for extraction and continuous testing. When cleaning the barrel-shaped structure, the equipment does not need to stop testing. The two barrel-shaped structures can also be used alternately to adapt to long-term and high-frequency AI screening of medicines.

[0048] Among them, the second transmission frames 9 for fixing the transmission tube 10 are arranged on both sides of the outside of the storage pool 2, and a bidirectional threaded rod 8 is arranged between the two second transmission frames 9. The threaded wall outside the bidirectional threaded rod 8 will be threadedly matched with the penetration position of the second transmission frame 9. The upper end of the second transmission frame 9 is connected to the sliding slot of the housing of the hair follicle drug screening detection device. After being restricted, the bidirectional threaded rod 8 will rotate and drive the two second transmission frames 9 to move relative to each other;

[0049] Specifically in this embodiment, Figure 5 As shown, connecting pipes 21 are sealed and arranged on both sides of the storage tank 2 facing the transmission pipe 10, and the connecting pipes 21 are connected to the card slots of the transmission pipe 10, and the transmission pipe 10 can be stuck outside the connecting pipe 21 by the lateral sliding of the second transmission frame 9, or the transmission pipe 10 can be separated from the connecting pipe 21 by the lateral sliding of the second transmission frame 9;

[0050] The medicine liquid transmitted at the position of the connecting tube 21 can directly fall on the lower end of the storage tank 2. After the medicine is transported to the storage tank 2, the medicine will not contact the connecting tube 21, so that after the subsequent transmission tube 10 is pulled out, the medicine inside the storage tank 2 will not flow out from the position of the connecting tube 21 without restriction;

[0051] Specifically, a connecting block 23 is provided at the lower end of the optical detection module, and the connecting block 23 has the same weight as the storage tank 2. First transmission frames 1 are provided on both sides between the connecting block 23 and the storage tank 2. The two first transmission frames 1 are threadedly matched with the connecting block 23 and the outer wall of the storage tank 2. The first transmission frame 1 can synchronously drive the connecting block 23 and the storage tank 2 to rotate and adjust the position through the transmission of the transmission group, wherein the connecting block 23 is mainly used to offset the weight of the storage tank 2 when the first transmission frame 1 is connected, so that the first transmission frame 1 can be stably set up in the middle position inside the drug screening detection device;

[0052] refer to Figure 1 and Figure 3The transmission group will transmit the bidirectional threaded rod 8 and the first transmission frame 1. A motor is provided on one side of the transmission block 7 in the transmission group. The output of the motor can make the bidirectional threaded rod 8 and the first transmission frame 1 connected by the transmission group rotate synchronously. The rotation of the bidirectional threaded rod 8 will drive the second transmission frame 9 to move relatively, and the rotation of the first transmission frame 1 can adjust the position of the storage tank 2.

[0053] like Figure 6 As shown, the motor drive connected to the transmission block 7 at one end of the bidirectional threaded rod 8 can synchronously drive the transmission structure inside the hair follicle drug screening and detection device to rotate and transmit synchronously. The synchronous transmission can avoid the need to manually press the switch at each position independently, and avoid the need to manually press the switch. The internal transmission structure needs to avoid collision and jamming during transmission. The synchronous transmission can achieve efficient detection of the medicine inside the storage tank 2. Similarly, the synchronous transmission can also adjust the position and direction of the storage tank 2 inside the hair follicle drug screening and detection device. The adjustment of the direction also facilitates the adjustable spray assembly 4 to spray pure water and perform direct cleaning.

[0054] Specifically in this embodiment, Figure 3 and Figure 4 As shown, the transmission group includes a transmission rod 5, a gear 6, a transmission block 7, a tooth groove 18 and a synchronous belt 24 for connecting the gear 6 and the transmission rod 5. The outer part of the tooth groove 18 is evenly distributed in the half area outside the transmission block 7. The tooth groove 18 is meshed and connected with the gear 6. After the tooth groove 18 rotates with the transmission block 7 and contacts the gear 6, it will drive the gear 6 to rotate, wherein the transmission block 7, the gear 6 and the transmission rod 5 are all rotatably connected with the housing of the hair follicle drug screening and detection device;

[0055] In addition, when the storage tank 2 is located at the upper end of the optical detection module and the connecting block 23 is located at the lower end of the optical detection module, the tooth groove 18 distribution area is located on one side of the upper end of the gear 6, so that the transmission block 7 will not contact the tooth groove 18 first when rotating counterclockwise, and the tooth groove 18 can only contact the gear 6 after the transmission block 7 rotates for a certain period of time, so that the second transmission frame 9 drives the transmission tube 10 to be pulled out from the position of the connecting tube 21, and then the storage tank 2 rotates;

[0056] The AI-based hair follicle drug screening and detection device of this embodiment stores the drugs in the storage pool 2 after detection through the lower storage frame 3 at the lower end of the first transmission frame 1. The storage pool 2 will flip over when driven by the transmission group, and the flipping of the storage pool 2 will actively dump the medicine inside, so that the medicine can fall into the lower storage frame 3, which is convenient for cleaning the lower storage frame 3. During the cleaning process of the storage pool 2, the adjustable spray assembly 4 arranged in an array at the middle position of the upper end of the lower storage frame 3 sprays pure water for cleaning;

[0057] The purified water required for cleaning and the medicine discharged from the storage tank 2 will directly flow into the lower storage frame 3, and the wastewater and medicine will be collected uniformly through the lower storage frame 3. The unified collection can improve the treatment effect of medicines and wastes, facilitate the subsequent unified and direct discharge, and avoid the tested medicines and the purified water for cleaning affecting the AI ​​screening and detection of subsequent medicines;

[0058] After the pure water is extracted and contacts the connection block 23, the wet storage tank 2 will affect the accuracy of subsequent drug testing, such as Figure 2 As shown, the fixed plate 11 at the upper end of one side of the lower storage frame 3 will slide horizontally and move to the lower end of the storage tank 2 after the flip, and a hot air blower 12 is provided at one end of the fixed plate 11. An array of exhaust holes 16 for exhaust are distributed at the upper end of the fixed plate 11, wherein the exhaust holes 16 are sealedly connected to the hot air blower 12. After the hot air blower 12 is started, gas can enter the storage tank 2, so that the storage tank 2 is restored to dryness after cleaning;

[0059] The exhaust holes 16 distributed in an array are all connected to the hot air blower 12. The dry hot air extracted and heated by the hot air blower 12 will be diverted through the exhaust holes 16. The exhaust holes 16 distributed in an array can make the heated dry gas evenly distributed inside the storage tank 2, so as to facilitate comprehensive drying of the inside of the storage tank 2 after cleaning, and facilitate efficient reuse of the storage tank 2 after cleaning.

[0060] Example 2

[0061] In order to facilitate the discharge of the medicine inside the storage tank 2 and prevent the medicine from being discharged and blocking the upper end of the adjustable spray assembly 4, as shown in FIG. Figure 5 As shown, drainage holes 14 are provided on both sides of the front end of the storage tank 2, and the drainage holes 14 penetrate and extend to both sides of the storage tank 2. Through the penetration of the drainage holes 14, the storage tank 2 can realize the discharge of the medicine during the flipping process, and prevent the medicine from falling on the drainage position of the adjustable spray assembly 4;

[0062] The liquid medicine transmitted by the transmission tube 10 will be gathered inside the storage tank 2 , and the level of the medicine will not be higher than the drainage hole 14 .

[0063] Example 3

[0064] A one-way threaded rod 13 is provided through the lower end of the outer wall of the hot air blower 12, and the outer part of the one-way threaded rod 13 is threadedly matched with the outer wall of the hot air blower 12. After being driven and rotated, the one-way threaded rod 13 can drive the fixed disk 11 and the hot air blower 12 to move horizontally, so that the fixed disk 11 can dry the storage tank 2 after cleaning the storage tank 2.

[0065] Example 4

[0066] The adjustable spray assembly 4 includes: an outer ring bracket 25 and an inner ring bracket 26, the outer ring bracket 25 and the inner ring bracket 26 are connected by a plurality of groups of connecting brackets 28, a plurality of groups of inner ring fan blades 27 are installed in the inner ring bracket 26, a plurality of groups of inner ring fan blades 27 are installed between the outer ring bracket 25 and the inner ring bracket 26, a driving motor 31 is fixedly arranged on the outer wall of the outer ring bracket 25, a driving gear 32 is fixedly sleeved on the output shaft of the driving motor 31, an annular driving member 33 is movably sleeved on the outer wall of the outer ring bracket 25, and the annular driving member 33 is connected to the outer ring bracket 25 by threads, a plurality of groups of meshing teeth 34 are arranged on the outer wall of the annular driving member 33, and the driving gear 32 is meshed with the plurality of groups of meshing teeth 34, a plurality of groups of supporting members 38 are fixedly arranged around the outer wall of the outer ring bracket 25, and each group of supporting members 38 is installed with the same rotating bearing 1 35, and the first rotating connecting member 37 is connected by a rotating bearing The first rotating connecting member 37 is connected to the outer ring bracket 25, and one end of the first rotating connecting member 37 extends out of the rotating bearing 35 and is fixedly connected to the driving connecting rod 36. The other end of the first rotating connecting member 37 is fixedly connected to the outer ring fan blades 29. The end of the driving connecting rod 36 away from the rotating bearing 35 is movably connected to the outer wall of the annular driving member 33. A plurality of groups of supporting grooves 41 and through holes 42 are provided on the inner ring bracket 26, and each group of supporting grooves 41 and through holes 42 are coaxially arranged. The same rotating bearing 40 is installed in each group of supporting grooves 41. The second rotating connecting member 39 is movably connected to the inner ring bracket 26 through the rotating bearing 40. One end of the second rotating connecting member 39 extends out of the rotating bearing 40 and is fixedly connected to the outer ring fan blades 29. The other end of the second rotating connecting member 39 passes through the through hole 42 and is fixedly connected to the inner ring fan blades 27. The outer ring fan blades 29 and the inner ring fan blades 27 located on the same axis are arranged perpendicular to each other.

[0067] Specifically, Figure 7 As shown in FIG. 1 , a circle of outer shell is sleeved on the outer wall of the outer ring bracket 25 , and the shell can protect the driving motor 31 and all the parts installed on the outer wall of the outer ring bracket 25 to prevent damage.

[0068] The working principle and beneficial effects of the above technical solution are as follows: In order to achieve all-round cleaning and ensure that the inside of the storage tank 2 is thoroughly cleaned, during cleaning, the annular drive member 33 is driven to rotate by starting the drive motor 31. Since the annular drive member 33 is connected to the outer ring bracket 25 through a thread, the annular drive member 33 is raised and lowered while rotating around the outer wall of the outer ring bracket 25. At this time, a plurality of groups of driving connecting rods 36 are deflected under the drive of the annular drive member 33, and then the outer ring fan blades 29 are driven to rotate by the annular drive member 33. By controlling the deflection angle of a plurality of groups of outer ring fan blades 29, the area of ​​the channel through which the water flows through the outer ring bracket 25 and the inner ring bracket 26 is changed. While changing the impact force of the water flow on the inner wall of the storage tank 2, the impact angle of the water flow can be changed, thereby achieving all-round cleaning of the inner wall of the storage tank 2. Moreover, since the outer ring fan blades 29 and the inner ring fan blades 27 located on the same axis are arranged perpendicular to each other, when the outer ring fan blades 29 move the outer ring fan blades 29 to the inner ring bracket 26, the outer ring fan blades 29 are arranged perpendicular to each other. When the channel between the outer ring bracket 25 and the inner ring bracket 26 is closed, the channel of the inner ring bracket 26 is in an open state, so that the water flow can be concentrated and then sprayed for cleaning. When the outer ring fan blades 29 open the channel between the outer ring bracket 25 and the inner ring bracket 26, the channel of the inner ring bracket 26 is in a closed state, so that the water flow can be dispersed into water mist or a large-scale water flow for flushing. It can also be adjusted to a semi-open and semi-closed mode for use, so as to adapt to the flow characteristics of different medicines, to detect different types of medicines, and to improve the cleaning effect of complex medicines or high-viscosity substances.

[0069] Example 5

[0070] Also includes:

[0071] A tension sensor, disposed on the synchronous belt 24, for monitoring the tension level of the synchronous belt 24 when in use;

[0072] A laser centering sensor, which is arranged on the inner wall of the detection device housing and is located on the same axis as the synchronous belt 24, and is used to monitor the offset of the synchronous belt 24 when in use;

[0073] A temperature sensor, disposed in the housing of the detection device, for monitoring the ambient temperature of the synchronous belt 24 when it is working;

[0074] A rotation speed sensor 1, arranged on the transmission rod 5, for monitoring the rotation speed of the transmission rod 5;

[0075] A second speed sensor is provided on the transmission block 7 and is used to monitor the speed of the transmission block 7;

[0076] A timer, arranged on the outer surface of the detection device, for monitoring the use time of the screening device;

[0077] An alarm, wherein the alarm is arranged on the outer surface of the detection device;

[0078] A controller, which is arranged on the outer surface of the detection device housing, and is electrically connected to the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, the timer, and the alarm respectively. The controller controls the alarm to work based on the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, and the timer, including:

[0079] Step 1: The controller calculates the strain state coefficient of the synchronous belt 24 during use based on the tension sensor, the laser centering sensor, the timer, the speed sensor 1, the speed sensor 2 and the formula (1):

[0080]

[0081] Wherein, X is the strain state coefficient of the synchronous belt 24 during use, F1 is the detection value of the tension sensor, F2 is the preset maximum tension that the synchronous belt 24 can withstand, n1 is the detection value of the speed sensor 1, n2 is the detection value of the speed sensor 2, L1 is the detection value of the laser centering sensor, R1 is the radius of the transmission rod 5, R2 is the radius of the motor output shaft that drives the transmission block 7 to rotate, s is the detection value of the timer, μ1 is the friction coefficient of the synchronous belt 24, θ is the Poisson's ratio of the material of the synchronous belt 24, S1 is the contact surface area of ​​the synchronous belt 24 and the transmission rod 5, E is the shear modulus of the synchronous belt 24, and ln is the natural logarithm with e as the base;

[0082] Step 2: Based on step 1, the controller calculates the life index of the synchronous belt 24 based on the temperature sensor and formula (II):

[0083]

[0084] Wherein, Y is the life index of the synchronous belt 24, is the preset maximum wear amount of the synchronous belt 24, T1 is the detection value of the temperature sensor, T2 is the current ambient temperature, K is the product of the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, and the accuracy of the timer (the value is greater than 0 and less than 1, which may be related to the length of time the sensor has been in use), Δ1 is the preset damage coefficient of the synchronous belt 24 (the value is greater than 0 and less than 1, which may be related to the length of time the synchronous belt 24 has been in use and the impact of the use environment on the synchronous belt 24), and e is a natural constant, which is 2.72;

[0085] Step three: the controller compares the life index of the synchronous belt 24 calculated in step two with a preset life index. When the life index of the synchronous belt 24 calculated in step two is less than the preset life index, the controller controls the alarm to issue an alarm prompt.

[0086] The working principle and beneficial effects of the above technical solution are as follows: too high tension will increase friction and burden, leading to premature wear of the belt and wheels, while too low tension will cause belt slippage and reduced transmission efficiency, and poor alignment of the pulley will cause unbalanced belt operation, resulting in side wear or excessive wear. Environmental factors such as temperature, humidity and dust will affect the life of the belt. The most important thing is that high temperature will accelerate the aging of rubber. Different belt materials (such as rubber, polyurethane) and types (such as V-belts, synchronous belts) have different durability and application ranges. Based on this, the above scheme can monitor the tension level of the synchronous belt 24 when it is in use through a tension sensor, a laser centering sensor to monitor the offset of the synchronous belt 24 when it is in use, and a temperature sensor to monitor the ambient temperature of the synchronous belt 24 when it is working. Then, the strain state coefficient of the synchronous belt 24 during use is calculated by formula (1), and the life index of the synchronous belt 24 is calculated by formula (2). The controller can control the alarm to work according to the life index of the synchronous belt 24. When the life index of the synchronous belt 24 calculated in step 2 is less than the preset life index (0.85), the controller controls the alarm to issue an alarm prompt, and the operator replaces the synchronous belt 24 in time according to the alarm, thereby improving the safety of the equipment.

[0087] Example 6

[0088] In order to make the optical detection module continue to face upward, Figure 1 As shown, both sides of the outer wall of the optical detection module are rotatably connected to the interior of the first transmission frame 1 through the connecting shaft 22;

[0089] Specifically, a counterweight block is suspended at the lower end of the outer wall of the optical detection module. The suspension of the counterweight block ensures that after the first transmission frame 1 rotates, the optical detection module will not be affected and will continue to face the upper end.

[0090] Working principle: When the device is used to screen hair follicle drugs, the most likely batch of drugs are calculated through AI and put into the screening and detection device in turn. The pump connected to one end of the transmission tube 10 extracts the drug and transmits it to the storage tank 2 through the transmission tube 10. The optical detection module at the lower end of the storage tank 2 is started. The optical detection module detects the data of the medicinal solution in the storage tank 2, detects and calculates the data with AI, and performs curve fitting to judge the effectiveness of the drug, thereby achieving a single screening. The motor will first drive the transmission block 7 to rotate, and the rotation of the transmission block 7 will directly drive the two-way threaded rod 8 to rotate. The rotation of the two-way threaded rod 8 will simultaneously generate relative motion with the two second transmission frames 9. After the second transmission frame 9 is restricted by the outer shell of the screening and detection device, the second transmission frame 9 drives the transmission tube 10 connected at the lower end to be pulled out from the connecting tube 21 position on both sides of the storage tank 2. In the process of the transmission block 7 driving the two-way threaded rod 8 to rotate, the transmission block 7 will drive the tooth groove 18 to rotate counterclockwise and move toward the gear 6. After the transmission tube 10 is pulled out, the tooth groove 18 will contact the gear 6 and generate The gear 6 rotates clockwise when the transmission block 7 rotates counterclockwise, and the rotation of the gear 6 is transmitted through the synchronous belt 24. The gear 6 drives the transmission rod 5 to rotate clockwise, and the rotation of the transmission rod 5 drives the storage tank 2 to rotate slowly clockwise through the first transmission frame 1. During the rotation, the storage tank 2 drives the internal medicine to pour out, so that the medicine can be discharged from the drainage hole 14. After the rotation of the storage tank 2, the storage tank 2 is aligned with the adjustable spray assembly 4, and the pump extracts pure water and discharges it from the adjustable spray assembly 4. The discharged liquid Experience actively cleaning the storage pool 2. After cleaning the storage pool 2, the rotation of the one-way threaded rod 13 can drive the fixed disk 11 and the hot air blower 12 to move toward the storage pool 2. Start the hot air blower 12, which draws external gas and heats it before discharging it from the exhaust hole 16. The hot air will dry the cleaned storage pool 2, and the clockwise rotation of the transmission block 7 will first drive the storage pool 2 to flip between the two second transmission frames 9 through the tooth groove 18. As the transmission block 7 continues to rotate, the second transmission frame 9 will drive the transmission pipe 10 to repeatedly insert the two sides of the outside of the storage pool 2.

[0091] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0092] While the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that many changes, modifications, substitutions and variations can be made to the embodiments without departing from the principles and spirit of the invention.

Claims

1. An AI-based hair follicle drug screening and detection device, comprising a storage tank (2), an optical detection module and transmission tubes (10) on both sides of the storage tank (2), characterized in that: A bidirectional threaded rod (8) is arranged at the upper end of the storage tank (2), and a first transmission frame (1) is arranged on both sides of the outside of the optical detection module. The bidirectional threaded rod (8) is driven by a transmission group to move the transmission tube (10) away from the storage tank (2), and then the first transmission frame (1) rotates again. The transmission group comprises a transmission rod (5), a gear (6), a transmission block (7), a tooth groove (18) and a synchronous belt (24) for connecting the gear (6) and the transmission rod (5). A tooth groove (18) is arranged on half of the circle of the transmission block (7), and the tooth groove (18) is meshed with the gear (6).

2. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: The transmission block (7) is welded to one side of the bidirectional threaded rod (8), and the transmission rod (5) is welded to one side of the first transmission frame (1). When the storage tank (2) is located at the upper end of the optical detection module, the outer tooth groove (18) of the transmission block (7) is located at one side of the upper end of the gear (6). The transmission block (7) rotates so that the tooth groove (18) contacts the gear (6) and then drives the gear (6) to rotate clockwise.

3. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: The bidirectional threaded rod (8) rotates and drives the transmission pipe (10) to move horizontally through threaded engagement with the second transmission frame (9), and both sides of the storage tank (2) are sealedly connected to the transmission pipe (10) via connecting pipes (21).

4. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: A connecting block (23) having the same weight as the storage tank (2) is provided at the lower end of the optical detection module, and the first transmission frame (1) is respectively fixed to the outer walls of the storage tank (2) and the connecting block (23) by bolts.

5. The AI-based hair follicle drug screening detection device according to claim 4, characterized in that: A lower storage frame (3) is provided at the lower end of the connection block (23); an adjustable spray assembly (4) is provided on the lower storage frame (3) toward the storage tank (2); and a hot air blower (12) is provided on one side of the upper end of the adjustable spray assembly (4).

6. The AI-based hair follicle drug screening detection device according to claim 5, characterized in that: A fixed plate (11) having an exhaust hole (16) is arranged on one side of the hot air blower (12) facing the adjustable spray assembly (4); the exhaust hole (16) faces the storage tank (2) and is sealedly connected to the hot air blower (12); and the storage tank (2) is driven by the transmission group to flip to the upper end of the fixed plate (11).

7. The AI-based hair follicle drug screening detection device according to claim 6, characterized in that: The hot air blower (12) is driven by a one-way threaded rod (13) to adjust its lateral position.

8. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: Drain holes (14) are provided on both sides of the front end of the storage tank (2), and the level of the medicine transferred to the inside of the storage tank (2) by the transfer pipe (10) is not higher than the drainage holes (14).

9. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: The adjustable spray assembly (4) comprises: an outer ring bracket (25) and an inner ring bracket (26), wherein the outer ring bracket (25) and the inner ring bracket (26) are connected via a plurality of groups of connecting brackets (28), a plurality of groups of inner ring blades (27) are installed in the inner ring bracket (26), and a plurality of groups of inner ring blades (27) are installed between the outer ring bracket (25) and the inner ring bracket (26), a driving motor (31) is fixedly arranged on the outer wall of the outer ring bracket (25), and a driving gear (32) is fixedly sleeved on the output shaft of the driving motor (31), The annular driving member (33) is movably sleeved on the outer wall of the outer ring bracket (25), and the annular driving member (33) and the outer ring bracket (25) are connected by threads. The outer wall of the annular driving member (33) is provided with a plurality of groups of meshing teeth (34), and the driving gear (32) is meshed with the plurality of groups of meshing teeth (34). A plurality of groups of supporting members (38) are fixedly provided around the outer wall of the outer ring bracket (25), and each group of supporting members (38) is installed with the same rotating bearing (35). The first rotating connecting member (37) is connected to the outer ring bracket (25) by rotating the bearing. The first rotating connecting member (37) is connected to the outer ring bracket (25), and one end of the first rotating connecting member (37) extends out of the rotating bearing (35) and is fixedly connected to the driving connecting rod (36). The other end of the first rotating connecting member (37) is fixedly connected to the outer ring fan blade (29). The end of the driving connecting rod (36) away from the rotating bearing (35) is movably connected to the outer wall of the annular driving member (33). The inner ring bracket (26) is provided with a plurality of groups of supporting grooves (41) and through holes (42), and each group of supporting grooves (41) and through holes (42) are The shaft is arranged, and each group of supporting grooves (41) is equipped with the same rotating bearing 2 (40). The second rotating connecting member (39) is movably connected to the inner ring bracket (26) through the rotating bearing 2 (40). One end of the second rotating connecting member (39) extends out of the rotating bearing 2 (40) and is fixedly connected to the outer ring fan blade (29). The other end of the second rotating connecting member (39) passes through the through hole (42) and is fixedly connected to the inner ring fan blade (27). The outer ring fan blade (29) and the inner ring fan blade (27) located on the same axis are arranged perpendicular to each other.

10. The AI-based hair follicle drug screening detection device according to claim 1, characterized in that: Also includes: a tension sensor, arranged on the synchronous belt (24), and used for monitoring the tension level of the synchronous belt (24) when in use; A laser centering sensor, arranged on the inner wall of the detection device housing and located on the same axis as the synchronous belt (24), for monitoring the offset of the synchronous belt (24) when in use; A temperature sensor, arranged in the housing of the detection device, for monitoring the ambient temperature of the synchronous belt (24) when it is working; A rotation speed sensor 1, arranged on the transmission rod (5) and used for monitoring the rotation speed of the transmission rod (5); A second rotation speed sensor, arranged on the transmission block (7) and used for monitoring the rotation speed of the transmission block (7); A timer, arranged on the outer surface of the detection device, for monitoring the use time of the screening device; An alarm, wherein the alarm is arranged on the outer surface of the detection device; A controller, which is arranged on the outer surface of the detection device housing, and is electrically connected to the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, the timer, and the alarm respectively. The controller controls the alarm to work based on the tension sensor, the laser centering sensor, the temperature sensor, the speed sensor 1, the speed sensor 2, and the timer, including: Step 1: The controller calculates the strain state coefficient of the synchronous belt (24) during use based on the tension sensor, the laser centering sensor, the timer, the speed sensor 1, the speed sensor 2 and the formula (1): Wherein, X is the strain state coefficient of the synchronous belt (24) during use, F1 is the detection value of the tension sensor, F2 is the preset maximum tension that the synchronous belt (24) can withstand, n1 is the detection value of the speed sensor 1, n2 is the detection value of the speed sensor 2, L1 is the detection value of the laser centering sensor, R1 is the radius of the transmission rod (5), R2 is the radius of the motor output shaft that drives the transmission block (7) to rotate, s is the detection value of the timer, μ1 is the friction coefficient of the synchronous belt (24), is the Poisson's ratio of the material of the synchronous belt (24), S1 is the area of ​​the contact surface between the synchronous belt (24) and the transmission rod (5), E is the shear modulus of the synchronous belt (24), and ln is the natural logarithm with e as the base; Step 2: Based on step 1, the controller calculates the life index of the synchronous belt (24) based on the temperature sensor and formula (II): Wherein, Y is the life index of the synchronous belt (24), is the preset maximum wear amount of the synchronous belt (24), T1 is the detection value of the temperature sensor, T2 is the current ambient temperature, K is the product of the accuracy of the tension sensor, the laser centering sensor, the temperature sensor, the first speed sensor, the second speed sensor, and the timer, Δ1 is the preset damage coefficient of the synchronous belt (24), and e is a natural constant, the value of which is 2.72; Step three: the controller compares the life index of the synchronous belt (24) calculated in step two with a preset life index. When the life index of the synchronous belt (24) calculated in step two is less than the preset life index, the controller controls the alarm to issue an alarm prompt.

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