Oral cavity jet pre-cleaning system

Abstract

Devices and systems for removing plaque / oral biofilm from a target surface or all surfaces of teeth and methods of use thereof. The apparatus includes a socket head (HO), a socket ball (130), and a pair of opposing double flaps (120a, 120b). The socket ball (130) is mounted in a joint housing (111) of the socket head (110), forming a socket ball joint (160). Two flaps (120a, 120b) are connected to the socket (HO) and extend downward. Each wing (120a, 120b) may include one or more cleaning elements, such as a water cannon, a water cannon fold (495, 496, 497), a large / micro nozzle, and / or a large / micro nozzle coupled water cannon. Systems (1000) containing a device for oral cleaning generally include one or more additional components configured to couple the device to an element for user operation and link the device to a flow path to provide a fluid / air flow path for supplying liquid and / or air to the device.

Description

Technical Field

[0001] The present invention generally belongs to the technical field of oral cleaning systems. Background Art

[0002] Oral biofilm is the main cause of the most common oral diseases, such as caries (decay) and periodontal (gum) disease. Therefore, effective daily control of dental plaque biofilm is very important for everyone (Jin et al., Oral Disease, 22:609-619 (2016); Jepsen et al., Journal of Clinical Periodontology, 44 (Suppl 18): S85-S93 (2017)).

[0003] The most commonly used are traditional toothbrushes and electric toothbrushes, but they cannot fully clean the interproximal areas of teeth. In order to clean all surfaces of teeth and the gums or subgingival areas at the same time, a toothbrush needs to be used in combination with another device such as a water jet. Cavitation water jets allow oral biofilm to be removed from the interproximal areas of teeth (e.g., tooth surfaces and dental implants) (Jahn, Journal of Oral Hygiene, 84: 114-120 (2010); Kato et al., Archives of Oral Biology, 57: 30-35 (2012); Yamada et al., Implant Dentistry, 26: 904-910 (2017); Agarwal et al., Biofouling, 30: 359-365 (2014); Ijiri et al., International Journal of Lightweight Materials and Manufacturing, 1: 12-20 (2018)).

[0004] However, currently available oral jet cleaning systems, such as oral irrigators, produce single jets at high frequencies, which may be uncomfortable for the user. In addition, the water jets must be directed at precise interproximal areas to remove debris and / or plaque. Precise manual manipulation is required to achieve effective disease prevention effects. The high incidence of gum disease in the general population demonstrates that existing systems are inadequate for effective control of dental plaque biofilm.

[0005] There remains a need to develop devices and systems that can effectively remove dental plaque biofilm.

[0006] It is an object of the present invention to provide improved devices and systems for oral cleaning.

[0007] Another object of the present invention is to provide a method for oral cleaning using the device and system. Summary of the invention

[0008] Devices (also referred to herein as "dome") and systems and methods of use thereof for removing dental plaque / oral biofilm from targeted or all surfaces of teeth are described herein. The dome described herein comprises a socket head, a socket ball, and a pair of opposing double side wings.

[0009] The wotou comprises two wing connecting membranes and a top portion. The top portion comprises at least one set of opposing sides and an opening located at or near the center of the top portion. The two wing connecting membranes are bonded to the set of opposing sides of the top portion. The two wing connecting membranes and the top portion may be formed as an integral piece, or may be formed of separate pieces attached to each other using a suitable method, such as heat bonding or gluing. The wing connecting membranes and the top portion together form a joint housing.

[0010] The socket ball comprises a head and a connection part. The head is located in the joint housing, and the connection part passes through the opening at the top to form a ball-and-socket joint.

[0011] Each double-sided wing is bonded to the proximal end of a wing connecting membrane by a connecting edge. Each wing connecting membrane comprises an inner surface and an outer surface, wherein a gap is located between the majority surface of the socket ball and the inner surface of each wing connecting membrane. The gap allows the socket ball to rotate within the joint housing and allows liquid and / or air to be appropriately delivered to the target surface or all surfaces of the target tooth for cleaning. Each double-sided wing extends downward from the wing connecting membrane bonded thereto. An open area is located at a connection area connecting each double-sided wing and the wing connecting membrane to which it is bonded. The open area is configured to allow movement of the wing.

[0012] Each double-sided wing comprises a cleaning film, a base and two side portions. The base is connected to the cleaning film by a bottom edge, and the side portions are connected to the cleaning film by a pair of opposing side edges. The cleaning film of each double-sided wing comprises an inner surface and an outer surface, wherein the outer surface of the cleaning film has a curvature so that the double-sided wing surrounds each target tooth when in use. The inner surface of the cleaning film comprises a vertical plane, optionally two or more vertical planes aligned side by side. The vertical plane, optionally each of the two or more vertical planes, has a curvature consistent with the outer curvature of one or more teeth. Each of the base and the two side portions of the wing has a curved shape so as to roll away from the periodontal tissue when in use.

[0013] One or both of the double wing can contain cleaning elements, optionally two or more cleaning elements, combined on the inner surface of the cleaning membrane and / or the bottom of the cleaning membrane. The cleaning element, optionally each of the two or more cleaning elements, can be a plurality of water cannons, a water cannon fold or two or more water cannon folds, a plurality of large nozzles, a plurality of micro nozzles or a plurality of water cannons coupled with a large or micro nozzle head.

[0014] Typically, each of the plurality of water cannons comprises a hollow barrel. The hollow barrel may be embedded in the inner surface of the cleaning membrane, creating an opening thereon. Each of the plurality of water cannons may be positioned such that it is perpendicular to the outer curvature of the target tooth. The hollow barrel may have any suitable shape, such as a tapered cylindrical shape.

[0015] The cannon fold or each of the two or more cannon folds incorporated on the inner surface of the cleaning film and / or the bottom of the cleaning film may contain a continuous channel along the bottom edge of the cleaning film. The channel has an opening directed at a certain angle toward the periodontal pocket and a depth sufficient to capture liquid / air and / or bubbles when in use. When two or more cannon folds are incorporated into the cleaning film, they may be arranged parallel to each other with a suitable distance between adjacent cannon folds.

[0016] The large / micro nozzles in a plurality of large / micro nozzles are projections protruding from the inner surface of the cleaning film. The large / micro nozzles can have any suitable shape and size, such as hemispherical, as long as it does not have sharp points or edges that may damage the tooth surface. Typically, the diameter of each large nozzle in a plurality of large nozzles can be in the range of from >1mm to about 5mm, from about 1.2mm to about 5mm, from about 1.5mm to about 3mm, such as about 1.5mm, from about 0.5mm to about 1mm, or from about 1mm to about 2mm; the diameter of each micro nozzle in a plurality of micro nozzles can be in the range of from about 0.1mm to about 1mm, from about 0.1mm to about 0.8mm, or from about 0.2mm to about 0.6mm, such as about 0.5mm.

[0017] Also disclosed is a system for removing dental plaque / oral biofilm from a target surface or all surfaces of a tooth. Typically, the system includes a dome, a conduit, and a hand unit as described herein. The hand unit includes a channel and two opposing ends. The dome is attached to one of the opposing ends of the hand unit via the conduit so that the channel of the hand unit is in fluid communication with a liquid and / or air source, and is in fluid communication with the conduit and the dome. The dome can be integral with the conduit or removably attached to the conduit. Alternatively or additionally, the conduit can be integral with the hand unit or removably attached to the hand unit. The hand unit can also include an ultrasonic vibrator, a circuit board or a controller, or a combination thereof. Optionally, the hand unit can also include a chamber for a rechargeable battery or a disposable battery, a gripping structure, an output display or an audio component, or a combination thereof.

[0018] The system may also include a base unit. The base unit includes a tank and a tube. The other opposite end of the hand unit (i.e., the opposite end not attached to the conduit) may be connected to the tank by a tube so that the channel of the hand unit is in fluid communication with the liquid in the tank. The base unit may also include an air channel configured to be in fluid communication with the channel of the hand unit via the conduit. The base unit may also include a motor and a pump, as well as an optional pressure regulator, a power switch, a charging port, a tube storage element, a bracket for holding an additional conduit, and / or a water supply element. In some forms, the base unit may include a power port or a power cord configured to connect the system to an external power source. The tank contained in the base unit has a body defined by one wall or two or more walls, and a lid. The lid of the tank may be integral with the body or removably attached to the body. In some forms, the tank may also include a drug inert port configured to allow drug tablets or drug solutions to be added to the tank. The drug inert port may be located anywhere on the tank, such as on the lid of the tank.

[0019] Also disclosed is a method for oral cleaning in a subject in need using a dome and system as described herein. Typically, the method includes (i) moving the dome along the subject's dental arch. During step (i), liquid and / or air is ejected through the outlet of the socket ball of the dome with a pressure in the range of from about 0.5psi to about 30psi, a pulse frequency in the range of from about 0.5Hz to about 50Hz, and / or a delivery pulse volume in the range of from about 0.1mL to about 150mL. In some forms, the method also includes providing ultrasonic vibration to the dome before and / or during step (i). The frequency of the ultrasonic vibration can be in the range of about 100 to about 5000 vibrations per second, about 500 to about 4000 vibrations per second, or about 1000 to about 3000 vibrations per second.

[0020] In some forms, the oral cleaning methods disclosed herein further include attaching the dome to the conduit and / or hand unit prior to step (i); placing the dome on the subject's teeth prior to step (i); activating a power source to the hand unit before or after step (i); selecting or adjusting power output, cleaning duration, ultrasonic vibration frequency, and / or ultrasonic vibration duration before or during step (i); maintaining the dome on the target tooth for a period of time; switching between liquid and air during step (i); and / or rinsing the mouth with mouthwash before and / or after step (i). BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1A-1B Various views of an exemplary dome 100 are depicted. Figure 1A A top view of an exemplary dome 100 is depicted. Figure 1B A bottom view of an exemplary dome is depicted. Figures 1C-1FAnother exemplary dome 100" is depicted in different views. Figure 1C A top view of an exemplary dome 100" is depicted. Figure 1D A bottom view of an exemplary dome 100" is depicted. Figure 1E A cross-sectional view of an exemplary dome 100" is depicted. Figure 1F A side view of an exemplary dome 100" is depicted.

[0022] Figure 2A-2B Depicted Figure 1A-1B A cross-sectional view of an exemplary dome depicted in FIG. Figure 2A Depicted are the bilateral flanks of the dome housing the incisors (incisors and canines). Figure 2B The bilateral wings of the dome housing the premolars and molars are depicted.

[0023] Figures 3A-3D Depicted Figures 1A-1C Different views of one wing of the exemplary dome depicted in FIG. Figure 3A A perspective view of a wing having two perpendicular geometric curvatures is depicted to accommodate the different surface curvatures of different forms of human teeth, including incisors / canines and / or premolars / molars. Figure 3B A lateral view of the ala is depicted, showing the curvature parallel to the premolar / molar surface. Figure 3C A lateral view of the wing is depicted, showing the curvature parallel to the buccal surface of the incisor / canine. Figure 3D A lateral view of the ala is depicted, showing the curvature parallel to the lingual surface of the incisor / canine.

[0024] Figure 4 Depicted Figure 3A A cross-sectional view of the wing is shown, illustrating that the curvature directs water and bubbles to flush from the top through the micro-gap interface, thereby precisely targeting the gingival sulcus (the depression below the gum line) and / or the periodontal pocket as the final destination.

[0025] Figures 5A-5D Depicted Figures 1A-1C Different views of one wing of the exemplary dome depicted in , showing the curvature of the left side, right side and base of the wing. Figure 5A Side view depicting the curvature of the base.

[0026] Figure 5B A perspective view depicting the curvature of the base. Figure 5C A partial side view depicting the curvature of the base.

[0027] Figure 5D A partial bottom view depicting the curvature of the side portion.

[0028] Figures 6A-6C Depicted is a side view of an exemplary wing with micro water cannons distributed across the bottom of the wing. Fig. 6ADepicted is a side view of a wing with micro-water cannons distributed on the curvature parallel to the surface of the premolar / molar. Figure 6B Depicted is a side view of a wing with micro-water cannons distributed on a curvature parallel to the buccal surface of the incisors / canines. Figure 6C Depicted is a side view of a wing with micro-water cannons distributed on a curvature parallel to the lingual surface of the incisors / canines.

[0029] Fig. 7A Depicted is a perspective view of an exemplary micro-water cannon having a nozzle tip protruding slightly above a panel surface and a barrel disposed beneath a geometric shape having an opening. Figures 7B-7D Depicted is a perspective view of an exemplary cleaning membrane incorporating a cavitation force generating ( Figure 7B )、Water cannon force( Figure 7C ) and tsunami force ( Fig.7D ) of large nozzles / water cannons. Fig. 7E Depicted is a cross-sectional view of multiple micro-nozzles across the curvature of a wing.

[0030] Figure 8 A cross-sectional view of an exemplary wing with a cannon fold is depicted.

[0031] Fig. 9A Depicted is a perspective view of one wing of an exemplary dome having multiple layers of water cannon folds directed toward the lingual surface of a tooth, the gum-to-tooth, or the gum-to-implant interface. Fig. 9B Depicted Fig. 9A Cross-sectional view of two double wings of the exemplary dome depicted in FIG.

[0032] Fig. 10A Depicted is a perspective view of one wing of an exemplary dome having a plurality of micro-nozzles bonded to the inner surface of a cleaning membrane. Fig. 10B Depicted Fig. 10A Cross-sectional view of two double wings of the exemplary dome depicted in FIG.

[0033] Figures 11A-11C Depicted are cross-sectional views of domes with different features. Fig.11A Depicted is a cross-sectional view of a dome with multiple micro-nozzles and water cannon folds on the wing. Fig. 11B Depicted is a cross-sectional view of a dome with multiple large nozzles and cannon folds on the wings. Fig. 11C Depicted is a cross-sectional view of a dome with multiple water cannons having large nozzle heads and cannon folds on the wings.

[0034] Fig.12 A schematic diagram of an exemplary oral jet cleaning system is depicted.

[0035] Fig.13AA side view of an exemplary oral jet cleaning system is depicted. Fig. 13B Depicted is a side view of an exemplary handle unit with a dome attached. Fig. 13C A side view of an exemplary handle unit is depicted. DETAILED DESCRIPTION

[0036] I. Equipment and Systems

[0037] Devices have been developed that can remove dental plaque / oral biofilm from targeted surfaces or all surfaces of teeth (e.g., lips / cheeks, tongue, interdental spaces, gingival sulci, and / or periodontal pockets). The device described herein is a dome-shaped cleaning device (also referred to herein as a "dome"). The dome is designed so that when in use, a high-speed water jet is coupled with ultrasound or vibration to produce various forces, targeting specific surfaces or all surfaces of the teeth surrounded by the dome. This allows for effective removal of dental plaque / oral biofilm, thereby preventing oral / periodontal (gum) disease and improving oral / periodontal health care by reducing the oral biomass, the load of oral / periodontal pathogens, and / or the level of oral / periodontal inflammation.

[0038] A. Dome

[0039] The dome can be detachably connected to the hand unit via a catheter, or incorporated into the system via a hand unit for oral cleaning. Specifically, a user can hold a hand unit having a dome operably connected thereto and move the dome along the dental arch, and separate the biofilm on each tooth by one or more of the following forces generated by the dome: (1) water cavitation microbubble suction, (2) ultrasonic vibration tsunami force, and (3) micro water jet force. These forces can minimize the wear of conventional toothbrush bristles on the tooth surface and maximize the removal of biofilm. The term "operably connected" refers to a direct or indirect connection between the dome and the hand unit.

[0040] 1. Components

[0041] Typically, the dome includes a socket head, a socket ball, and a pair of opposite double-sided wings. The socket ball is mounted in a joint housing of the socket head to form a socket ball joint. The double-sided wings are connected to the socket head. Optionally, each wing of the dome includes one or more cleaning elements, such as multiple water monitors, one or more water monitor folds, multiple macro / micro nozzles, or multiple macro-micro nozzle coupled water monitors, or a combination thereof.

[0042] a. Wotou and Woqiu

[0043] The socket head includes two wing connecting membranes and a top portion, which together form a joint housing. The joint housing has a suitable shape and size so that it accommodates the socket ball, allowing the socket ball to rotate in the joint housing. The two wing connecting membranes are on a set of opposite sides of the top portion. The top portion includes an opening located at or near the center of the top portion. The opening is a shaped hole, such as a circular hole, a D-shaped hole, a star-shaped hole, an oval hole, or a tooth-shaped hole, which is configured to cooperate with the connection portion of the socket ball. In use, the ball and socket joint can be tilted according to the position of the target tooth to be coupled.

[0044] The socket ball has a head and a connecting portion. The head of the socket ball is located in the joint housing, and the connecting portion passes through the opening at the top for connecting with the conduit for delivering liquid / air to form a socket ball joint (also referred to herein as a "spherical joint"). The connecting portion can have any suitable shape and size, as long as it corresponds to the shape and size of the opening on the top of the socket head, so that it can pass through the opening and be connected to the conduit. The gap is between most of the surface area of ​​the socket ball and the inner surface of each wing connecting membrane to allow the movement of the socket ball and / or the wing connecting membrane so that the socket ball can rotate in the joint housing and allow liquid / air to be properly delivered to the target surface or all surfaces of the target tooth for cleaning. For example, the head of the socket ball can be positioned to tilt toward the inner surface of a bilateral wing and at an angle relative to the central axis of the dome. The angle can be approximately 0 to 60 degrees, approximately 0 to 50 degrees, approximately 0 to 40 degrees or approximately 0 to 30 degrees, for example approximately 30 degrees, depending on the position of the target surface of the target tooth.

[0045] The socket ball comprises a liquid / air passage through the central axis of the socket ball, and the passage terminates in an outlet. The liquid / air passage is communicated with the conduit fluid so that water and / or air are provided to the liquid / air passage by the conduit, and then rinsed to the target surface or all surfaces (such as lip / cheek, tongue, interdental space, gingival sulcus and / or periodontal pocket) of the target tooth by the outlet. The conduit can be any suitable rigid or flexible device for delivering liquid / air to the dome from a liquid / air source, such as a hollow object, tube, passage, pipeline, etc. with a suitable shape. The conduit can be configured so that it bends in a position close to the socket ball. This configuration allows the user to easily put the dome into his / her mouth for cleaning.

[0046] b. Double wing

[0047] Each double-sided wing of the dome is bonded to the proximal end of a wing connecting membrane (also referred to herein as a "corresponding wing connecting membrane") by a suitable technique, such as thermal bonding. Optionally, a pair of wings and their corresponding wing connecting membranes are integral pieces (i.e., single-piece structures), such as formed by molding, 3D printing, or integral casting. Each double-sided wing extends downwardly from its corresponding wing connecting membrane. The open area is located at the connection area connecting each wing and its corresponding wing connecting membrane. The open area is configured to allow movement of the wing so that an imaginary vertical measurement line (e.g., see Figure 2A and 2B , 171) and the angle between each wing can be changed during ultrasonic vibration and / or accommodate teeth of different sizes. Figure 2A and 2B As shown, each of the bilateral wings 120a and 120b forms a first angle α1 with an imaginary vertical measurement line 171 (which is aligned with the central vertical axis of the socket) to accommodate the incisors and / or canines ( Figure 2A ) and forms a second angle α2 with the imaginary vertical measurement line 171 to accommodate the premolars and / or molars ( Figure 2B ). The second angle α2 is greater than the first angle α1 because the width of the premolars and molars is greater than that of the incisors and canines. The open area can have any suitable shape and size, such as triangle, rectangle, square, trapezoid, cut line, etc. As long as it is located in the connection area and allows the movement of the wing.

[0048] Each double wing comprises a cleaning membrane having an inner surface and an outer surface, a base and two side portions (see, e.g. Figure 3A and 5B , 121, 123, 125, 127, 129a and 129b). The base is connected to the cleaning film by a bottom edge; the side is connected to the cleaning film by a pair of opposite side edges; and the cleaning film is connected to the wing connecting film of the cornbread by a connecting edge. The connecting edge, the bottom edge and the two side edges define the length (L) and width (W) of each wing. For example, Figure 5BAs shown, the length L is measured from the connecting edge 173 to the bottom edge 175, and the width W is measured from the first side edge 177a to the second side edge 177b. The length (L) and width (W) of each wing are sufficient to cover the labial / buccal and lingual surfaces of the teeth. For example, the length (L) of each of the two wings is in the range of from about 10 mm to about 20 mm, optionally in the range of from about 10 mm to about 18 mm or from about 10 mm to about 16 mm, for example about 11 mm, and the width (W) is in the range of from about 5 mm to about 25 mm, optionally in the range of from about 5 mm to about 20 mm, from about 10 mm to about 20 mm, or from about 5 mm to about 8 mm, for example about 6 mm or about 18 mm. The distance between the bottom edges of the two side wings can be in the range of from about 5 mm to about 25 mm, from about 5 mm to about 20 mm, from about 5 mm to 15 mm, or from about 5 mm to 10 mm. As an example, Figure 3A The exemplary dome 100 shown in has a wing length (L) of approximately 11 mm and a wing width (W) of approximately 11 mm, both of which can be modified to any of the above ranges. For example, although not shown, the exemplary dome 100 can be modified to be larger, such as having a wing length (L) in the range from 11 mm to 22 mm (approximately 11 mm, approximately 18 mm, or approximately 22 mm), and a wing width (W) in the range from 10 mm to approximately 22 mm (approximately 11 mm, approximately 18 mm, or approximately 22 mm), or the exemplary dome 100 can be modified to be smaller, such as having a wing length (L) in the range from 10 mm to 15 mm and a wing width (W) in the range from approximately 4 mm to approximately 5 mm. The maximum distance between the inner and outer surfaces of the cleaning membrane defines the thickness (T) of the wing (see, for example, Figure 3B-3D ). The thickness T is generally sufficient to incorporate one or more cleaning elements on the inner surface, as described in detail below. For example, the thickness of each double wing is in the range of 1 mm to 5 mm, 2 mm to 5 mm, 2 mm to 4 mm, such as 3 mm to 4 mm.

[0049] i. Curvature

[0050] The outer surface of each cleaning film of the wing has a curvature so that the two wings surround each target tooth. Typically, the outer surface is smooth to minimize discomfort during cleaning. Typically, the thickness of the wing is sufficient to accommodate a mirror image of the tooth surface to allow the wing to move fully during operation.

[0051] The inner surface of each cleaning membrane comprises at least one vertical plane, optionally two vertical panels aligned side by side (see, for example, Figure 3A, 122, 124). Each panel includes a curvature that matches the outer curvature of one type of tooth (e.g., premolars / molars or incisors / canines). For example, Figures 3A-3D As shown, each panel 122 and 124 includes a curvature 182 that conforms to the outer curvature of the premolars / molars; a curvature 184 that conforms to the buccal curvature of the incisors / canines; and / or a curvature 186 that conforms to the lingual curvature of the incisors / canines. Figure 3B-3D The dashed lines in the figure show the different curvatures on the inner surface of the cleaning film from the side, which correspond to the outer curvatures of the premolars / molars ( Figure 3B ), buccal curvature of incisors / canines ( Figure 3C ) and the lingual curvature of the incisors / canines ( Figure 3D ) are consistent.

[0052] The different curvatures incorporated on the inner surface of each cleaning film allow the dual wing to conform to the different curvatures of some or all types of a person's teeth. As the dome moves along the dental arch, at least one panel on each wing contains a curvature that conforms to the buccal / labial and lingual curvatures of each tooth. Figure 4 As shown, in use, water and bubbles rush out from the outlet of the socket, creating two interface micro-gaps: a first interface micro-gap between the lip / cheek of the treated tooth (also referred to herein as the "target tooth") and its corresponding curvature on the inner surface of the cleaning film (see, for example, Figure 4 , 191), and a second interface microgap between the lingual surface of the tooth and its corresponding curvature on the inner surface of the cleaning film (see e.g. Figure 4 , 192). "Corresponding curvature" refers to the curvature on the inner surface of the cleaning film that corresponds to the outer surface (lip / cheek or tongue) of the target tooth.

[0053] The interface microgaps between the outer surfaces of the target teeth and their corresponding wing curvatures can guide liquid / air and / or bubbles to flush through these microgaps, creating a hydrofoil effect and rushing toward the gingival sulcus (e.g., the depression below the gum line) and / or the tomography of the periodontal pocket to separate and flush away the oral biofilm. Optionally, when ultrasonic vibrations are applied, these microgaps also allow ultrasonic vibration waves to be emitted in a vertical direction toward the surface of the target teeth to separate the oral biofilm. As the dome moves along the dental arch from the left posterior molar to the right posterior molar, each tooth is treated in turn.

[0054] ii. Side and base

[0055] The base of each wing is connected to the cleaning membrane via a bottom edge and extends along the entire width of the wing from a first side edge to an opposite second side edge (see, for example, Figure 5B , 127). Each side portion is connected to the cleaning membrane of the wing by a first or second side edge (see, for example, Figure 5B, 129a and 129b). The base and each of the two side portions of the wing have a curved shape so that when the dome moves along the dental arch, it rolls away from the periodontium to minimize any traumatic effects on the periodontium. Figure 5A As shown, instead of pointing toward the periodontal tissue and creating a sharp contact edge with the periodontal tissue when in use (dashed line), the base 127 of the wing has an OMEGA shape (solid line) that rolls outward from the periodontal tissue and provides a smooth contact edge with the periodontal tissue. Figure 5C As shown, the OMEGA-shaped base 127 is connected to the cleaning film 121 ( Figure 5C The bottom edge 175 (not visible in FIG. 1 ) is rolled outward and upward. For example, Figure 1A and 1B As shown, each of the two side portions 129a and 129b on each wing is rolled outward and inward from the side edge 177a or 177b, and is connected to the cleaning film 121 by the side edge 177a or 177b. The distal end of each side portion (i.e., 139a or 139b) is located at a distance D1 (measured from an imaginary horizontal measurement line Lm1 passing through the center of the opening 117) that is greater than the distance D2 (measured from the imaginary horizontal measurement line Lm1 to the inner surface of the cleaning film 121), so that the side edge of each wing does not contact the periodontal tissue at any sharp point.

[0056] The base and each of the two side portions of the wing may have other curved shapes as long as it can avoid contacting the periodontal tissue with any sharp contact.

[0057] c. Cleaning components

[0058] Optionally, one or both wings of the dome contain one or more cleaning elements incorporated on the inner surface of the cleaning membrane(s). Examples of cleaning elements include, but are not limited to, multiple water cannons, one or more water cannon folds, multiple macro / micro nozzles, and multiple water cannons coupled to macro or micro nozzle heads, and combinations thereof.

[0059] i. Water cannon

[0060] A plurality of water monitors may be incorporated on the inner surface of the cleaning membrane(s) of one wing or both wings of the dome. Alternatively, a plurality of water monitors are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Alternatively, a plurality of water monitors are incorporated on the inner surface of the cleaning membrane of both double-sided wings of the dome.

[0061] The water cannon comprises a hollow barrel embedded in the inner surface of the cleaning membrane, on which an opening is created. The hollow barrel is positioned perpendicular to the corresponding curvature so that it is also perpendicular to the outer curvature of the target tooth, such as the outer curvature of the premolar / molar, the labial surface of the premolar / molar, or the lingual surface of the incisor / canine. The barrel can capture liquid / air and / or bubbles flowing through the interface micro-gap and eject the captured liquid / air and / or bubbles toward the outer surface of the target tooth when ultrasonic vibrations are applied.

[0062] The hollow barrel of the water monitor can have any suitable shape and size, as long as it has sufficient volume to capture flushing liquid / air and / or bubbles. For example, the barrel can have any regular shape, such as spherical, cylindrical, conical, cubic, rhombic, hemispherical, pyramidal, triangular prism, hexagonal, star-shaped, cuboid, tetrahedron, trapezoid, etc., or irregular shape. Preferably, the barrel has a tapered cylindrical geometry. The hollow barrel has a depth (d1) measured from the opening of the water monitor to the bottom of the barrel (e.g., see Fig. 7A , d1). The depth of the barrel (d1) can be adjusted to obtain the desired force, ejection distance and direction of the target tooth. For example, the depth of the barrel (d1) ranges from about 0.1 mm to about 5 cm, from about 1 mm to about 4 cm, or from about 2 mm to about 3 mm. The barrel or each barrel bonded to the inner surface of the cleaning film can have a diameter ranging from 1 mm to 3 mm.

[0063] The opening of the water monitor can have any geometric shape and size, as long as it allows the trapped liquid / air and / or bubbles to be ejected from the barrel. Exemplary geometric shapes of the opening include, but are not limited to, circular, elliptical, trapezoidal, square, rectangular, triangular, star, diamond, elliptical, heart-shaped, polygonal, cross, semicircular, etc., and irregular geometric shapes. For example, the opening of the water monitor has a circular geometry with a diameter ranging from about 0.1 mm to about 10 mm, from about 1 mm to about 8 mm, from about 2 mm to about 5 mm, or from about 2 mm to about 3 mm.

[0064] The cleaning membranes may include water cannons of the same shape with the same or different sizes, or water cannons of different shapes and sizes. When both cleaning membranes include multiple water cannons coupled thereto, the first cleaning membrane may have water cannons of the same shape with the same or different sizes as the second cleaning membrane, or water cannons of different shapes and sizes than the second cleaning membrane.

[0065] ii. Water cannon folding part

[0066] One or more monitor folds may be incorporated into the inner surface or bottom of the cleaning membrane(s) of one or both wings of the dome.

[0067] Optionally, a monitor fold is incorporated into the inner surface of the cleaning membrane of a wing (see, for example, Figure 8 , 395) or in each cleaning film of the double wing. The cannon fold is a continuous channel located above and along the bottom edge of the wing. The channel can have any suitable shape, such as a tapered cylindrical, trapezoidal, conical, semi-cylindrical, hemispherical, etc. The cannon fold extends from a first side edge of the wing to an opposite second side edge. The cannon fold has an opening pointing at a certain angle to the periodontal pocket, and a depth (d2) measured from the opening 399 to the bottom of the channel (see, for example Figure 8 , d2). The depth (d2) of the water cannon fold is sufficient to capture liquid / air and / or bubbles so that, when ultrasonic vibrations are applied, the water cannon fold can capture the liquid / air and / or bubbles and then eject the captured liquid / air and / or bubbles toward the gingival sulcus and / or periodontal pocket. The depth (d2) of the water cannon fold can be adjusted to obtain the desired force, ejection distance and direction of the target tooth. For example, Figure 8 The exemplary monitor fold 395 shown has a d2 in the range of about 1 mm to about 2 mm.

[0068] Optionally, more than one cannon fold is incorporated into the inner surface of the cleaning film. Two or more cannon folds can be arranged parallel to each other with a suitable distance between adjacent cannon folds. Each cannon fold extends from a first side edge of the wing to an opposite second side edge and has an opening directed toward the gingival sulcus, periodontal pocket and / or gum-implant interface. For example, Fig. 9A and 9B As shown, three water cannon folds 495, 496 and 497 are combined on the cleaning film 421 of the wing 420a. The three water cannon folds 495, 496 and 497 are arranged parallel to each other on the inner surface of the cleaning film, with a distance (i.e., d3a, d3b) between adjacent water cannon folds. The first distance d3a can be the same or different from the second distance d3b. Each water cannon fold 495, 496 and 497 has an opening 491, 492 and 493, respectively, pointing to the gingival sulcus, periodontal pocket and / or gingival implant interface.

[0069] As described above, the curvature on the inner surface of the cleaning film allows liquid / air and / or bubbles to rush through the interface micro-gaps via the hydrofoil effect toward the target surface of the target tooth, the gingival sulcus (e.g., the depression below the gum line), and / or the tomography of the periodontal pocket. Incorporating one or more water cannon folds in the cleaning film provides an additional feature for the periodontal pocket for effectively removing biofilm by spraying liquid / air and / or bubbles directly into the periodontal pocket.

[0070] iii. Large and micro nozzles

[0071] A plurality of large and / or micro nozzles may be incorporated on the (multiple) inner surfaces of the (multiple) cleaning membranes of one wing or both wings of the dome. Optionally, a plurality of large nozzles are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a plurality of large nozzles are incorporated on the inner surface of the cleaning membrane of the two double-sided wings of the dome. Optionally, a plurality of micro nozzles are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a plurality of micro nozzles are incorporated on the inner surface of the cleaning membrane of the two double-sided wings of the dome. Optionally, a first plurality of large nozzles and a second plurality of micro nozzles are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a first plurality of large nozzles and a second group of micro nozzles are incorporated on the inner surface of the cleaning membrane of the double-sided wings of the dome.

[0072] The macro or micro nozzle protrudes from the inner surface of the cleaning film. The macro / micro nozzle can have any suitable shape, such as a hemispherical shape, as long as it has no sharp points or edges that may damage the tooth surface. For example, the macro or micro nozzle has a hemispherical cone protruding from the inner surface of the cleaning film (see, for example, Fig. 10A and 10B , 591). Typically, the diameter of a micro nozzle can be in the range of about 0.1 mm to about 1 mm, about 0.1 mm to about 0.8 mm, or about 0.2 mm to about 0.6 mm, such as about 0.5 mm; the diameter of an extra large nozzle can be in the range of from >1 mm to about 5 mm, from about 1.2 mm to about 5 mm, from about 1.5 mm to about 3 mm, such as from about 1.5 mm, from about 0.5 mm to about 1 mm, or from about 1 mm to about 2 mm.

[0073] Combining multiple macro and / or micro nozzles on the inner surface of one or both cleaning films of the wing can generate radial tsunami waves in the direction of reaching hidden surfaces and / or corners to separate oral biofilms by shear forces. Due to their larger size, macro nozzles can generate greater radial forces than micro nozzles. The selection of macro or micro nozzles or a combination thereof depends on the condition being treated, the user and the beneficial effect being sought, especially the specific user. For example, to treat children's teeth, a micro nozzle is selected to apply a gentle force on the surface (multiple) of each target tooth.

[0074] The number and position of the large or micro nozzles incorporated on the (multiple) inner surfaces of the cleaning film can vary and are determined according to the conditions being treated, the user, and the beneficial effects sought. The number and position of the large or micro nozzles can be configured to generate a desired radial force and direct the generated radial force to one or more desired directions for one or more specific tooth surfaces. For example, the number of large nozzles incorporated on the inner surface of the cleaning film of only one wing or each wing of the double-sided wing is in the range of from 4 to 24, from 6 to 20, from 8 to 16, or from 10 to 14. For example, the number of micro nozzles incorporated on the inner surface of the cleaning film of only one wing or each wing of the double-sided wing is in the range of from 10 to 80, from 15 to 60, from 20 to 50, from 20 to 40, or from 20 to 30.

[0075] For example, Fig. 11B The exemplary dome 700 shown includes three large nozzles on each vertical panel on the inner surface 723 of the cleaning membrane 721, i.e., a total of twelve large nozzles are incorporated on the inner surface of the cleaning membrane (from Fig.12 Only the three large nozzles are visible in the side view shown in B). Fig. 10A and 10B The illustrated exemplary dome 500 includes more than 25 micro-nozzles, such as 26, 27 or 28 micro-nozzles, bonded to the inner surface 523 of the cleaning membrane 521 of each of the double wings 520a and 520b, such that the total number of micro-nozzles in the dome is more than 50.

[0076] The shapes and / or sizes of the macro- and micro-nozzles incorporated on the inner surface of the same cleaning film may be the same or different. When the first wing of the dome includes a plurality of macro- and / or micro-nozzles on the inner surface of its cleaning film, the second wing of the dome may or may not include any macro- and micro-nozzles. When the second wing of the dome also includes macro- and / or micro-nozzles, their number, shape and / or size may be the same as or different from that of the first wing.

[0077] iv. Water cannon with large and micro nozzle heads

[0078] A plurality of water cannons with large and / or micro nozzle heads can be incorporated on the (multiple) inner surfaces of the (multiple) cleaning membranes of one wing or both wings of the dome. Optionally, a plurality of water cannons with large nozzle heads are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a plurality of water cannons with large nozzle heads are incorporated on the inner surface of the cleaning membrane of two double-sided wings of the dome. Optionally, a plurality of water cannons with micro nozzle heads are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a plurality of water cannons with micro nozzle heads are incorporated on the inner surface of the cleaning membrane of two double-sided wings of the dome. Optionally, a first plurality of water cannons with large nozzle heads and a second plurality of water cannons with micro nozzle heads are incorporated on the inner surface of the cleaning membrane of one wing of the dome. Optionally, a first plurality of water cannons with large nozzle heads and a second plurality of water cannons with micro nozzle heads are incorporated on the inner surface of the cleaning membrane of two double-sided wings of the dome.

[0079] The water cannon is as described above, i.e., comprises a hollow barrel embedded in the inner surface of the cleaning membrane, in which an opening is created. The barrel is positioned perpendicular to the corresponding curvature so that it is also perpendicular to the outer curvature of the target tooth, such as the outer curvature of a premolar / molar, the labial surface of a premolar / molar, or the lingual surface of an incisor / canine. The barrel can have any suitable shape and size, such as any of the shapes and sizes described above, which provides sufficient volume to capture irrigation liquid / air and / or bubbles. The macro and / or micro nozzle tip is a protrusion protruding from the inner surface of the cleaning membrane surrounding the opening of the water cannon (e.g., see Figures 6A-6C , 292 and Fig. 11C , 891). Typically, the diameter of a micro nozzle tip can be in the range of from about 0.1 mm to about 1 mm, from about 0.1 mm to about 0.8 mm, or from about 0.2 mm to about 0.6 mm, such as about 0.5 mm; the diameter of a macro nozzle tip can be in the range of from >1 mm to about 5 mm, from about 1.2 mm to about 5 mm, from about 1.5 mm to about 3 mm, or from about 1 mm to about 2 mm, such as about 1.5 mm.

[0080] Water cannons with macro and / or micro nozzle tips on the inner surface of the cleaning membrane can be operated in a bouncing mode triggered by ultrasonic vibrations (see, for example, Figure 7C ) capture and eject liquid / air and / or bubbles to generate water cannon force, as well as radial tsunami force promoted by the nozzle tip (see for example Fig.7D ).

[0081] The shapes and / or sizes of the water monitors coupled to the inner surface of the same cleaning membrane may be the same or different. Water monitors having the same or different shapes and / or sizes may have nozzle heads having the same or different shapes and / or sizes. When the first wing of the dome includes a plurality of water monitors having macro and / or micro nozzle heads on the inner surface of its cleaning membrane, the second wing of the dome may or may not include any water monitors coupled to the macro or micro nozzle heads. When the second wing of the dome also includes water monitors having macro and / or micro nozzle heads, their number, shape and / or size may be the same or different from that of the first wing.

[0082] 2. Force

[0083] In use, liquid / air and / or ultrasonic vibrations are flushed / applied to the dome; the ultrasonic vibrations coupled with the curvature on the inner surface of the cleaning membrane of each wing can generate cavitation forces by bursting bubbles that release energy, thereby generating suction forces on the biofilm (see, for example, Figure 7B ). In addition, when one or more cleaning elements as described above are incorporated on the inner surface of each cleaning film, one or more additional forces can be generated, such as a water cannon force that captures and ejects liquid / air and / or bubbles through a bouncing mode triggered by ultrasonic vibrations (see, e.g. Figure 7C ), and / or radial tsunami forces promoted by the nozzle tip (see e.g. Fig.7D ).

[0084] a. Cavitation force

[0085] The water gap hydrofoil effect is generated when the liquid flushes the interface microgap between the inner surface of the cleaning film and the outer curvature of the target tooth. Upon application of ultrasonic vibrations, the bubbles rupture, such as by vigorous wing flapping, releasing energy to generate suction to detach oral biofilm (e.g., see Figure 7B ).

[0086] b. Water cannon force

[0087] The combination of water cannons, water cannon folds, and / or water cannons with large and / or micro nozzle tips allows the generation of water cannon forces (see, e.g., Figure 7C ). When the ultrasonic vibrations cause the small faceted surface of the water monitor's barrel to retract or the water monitor's channel to fold back, liquid / air and / or bubbles are trapped inside the barrel or channel. When it rebounds forward, it ejects the liquid / air and / or bubbles outward and toward the target surface of the tooth, like a liquid / air bullet.

[0088] c. Tsunami force

[0089] The combination of macro- and / or micro-nozzles and / or water cannons with macro- and / or micro-nozzle heads allows the use of water and ultrasonic vibrations to generate tsunami forces (see, for example, Fig.7D). Since each panel on the inner surface of the cleaning film conforms to the outer curvature of the target tooth, the ultrasonic vibration can transmit a vertical force to destroy the oral biofilm from the tooth surface. Fig.7D As shown, ultrasonic vibrations from a hemispherical large nozzle tip deliver radial forces to shear oral biofilm from the tooth surface.

[0090] 3. Materials that form the dome

[0091] Suitable materials for forming the dome include, but are not limited to, elastomeric materials such as ethylene vinyl acetate (EVA), thermoplastic elastomers (TPE), or silicone. Such materials allow for movement of the socket ball, wing connecting membrane, and bilateral wings, and are softer and more pliable for wing flapping and protection of teeth and / or gums if in direct contact with the teeth and / or gums. Because the flexible dome has the ability to conform to the teeth and / or gums, it can also provide acceptable fit for a wide range of users.

[0092] B. Other components

[0093] The domes described herein can be included in a system comprising a dome and one or more additional components. The one or more additional components are configured to couple the dome to an element for user operation and link the dome to a flow path, providing a fluid / air flow path for supplying liquid and / or air to the dome.

[0094] Typically, the system comprises a base unit, a hand unit, a catheter and a dome. The dome is attached to the hand unit via the catheter, optionally detachably attached to the hand unit via the catheter. The base unit comprises a pump for controlling pressure, pulse frequency and / or dome speed.

[0095] 1. Catheter

[0096] The conduit of the system may be any suitable rigid or flexible device for delivering liquid / air from a liquid / air source to the dome, such as a hollow object of suitable shape, a tube, a channel, a conduit, etc. Suitable materials for forming the conduit include metals and natural and synthetic polymers, such as plastics, grade 5 titanium, titanium alloys, nickel titanium alloys, cobalt chromium alloys, stainless steel alloys, copper alloys, iron and / or iron alloys, nickel chromium alloys, zinc and zinc-plated materials, tantalum, Kanthal alloys or copper nickel alloys.

[0097] The dome is attached to the hand unit via a catheter. The dome may or may not be detachable from the catheter. For example, the connection portion of the dome is integral with the first opposite end of the catheter so that the dome and the catheter are a one-piece component. Alternatively, the dome is detachable from the catheter so that different domes with different wing curvatures can be selected and attached to the catheter and thus fixed to the hand unit for operation.

[0098] 2. Hand unit

[0099] The hand unit of the system can have any suitable shape and size so that a user can hold it, properly position the dome operably attached thereto on the user's teeth, and move the dome along the dental arch. The hand unit is typically made of a non-conductive material, such as plastic or a non-conductive polymer.

[0100] The hand unit typically has two opposing ends: a first opposing end of the hand unit incorporates a second coupling feature that corresponds to the first coupling feature of the catheter; and a second opposing end of the hand unit optionally incorporates a third coupling feature that corresponds to a charging port of the base unit or a stand. Optionally, the hand unit uses a rechargeable battery, a disposable battery, or it is electrically connected to an external power source, and the second opposing end of the hand unit does not incorporate any coupling feature. The third coupling feature can have any suitable shape and size, such as an indentation, as long as it can electrically couple to the charging port of the base unit or cooperate with a stand of the base unit that can hold the hand unit, optionally in an upright position.

[0101] The hand unit contains channels through which liquid / air flows from the liquid / air source, ultrasonic vibrator, circuit board, controller and optional battery compartment for holding rechargeable or disposable batteries to the conduit and dome.

[0102] a. Channel

[0103] The channel is in fluid communication with a liquid / air source, for example, connected to a tube connected to a liquid and / or air source. The conduit is coupled to the hand unit via the first and second coupling features as described above, and is in fluid communication with the channel. This configuration allows liquid and / or air to flow from the liquid and / or air source into the channel in the hand unit, into the conduit, and then into the dome.

[0104] b. Battery chamber and ultrasonic vibrator

[0105] The hand unit may include a battery compartment for housing one or more rechargeable or disposable batteries or battery packs. In some forms, the hand unit may include a cord for plugging into a power source. In such forms, the hand unit may or may not include a battery compartment for housing rechargeable or disposable batteries. In forms where the hand unit does not include a battery compartment for housing rechargeable or disposable batteries, the base unit may include a power source electrically connected to the hand unit. Optionally, the base unit includes a power plug or a power cord to which a power plug is attached to allow the system to be electrically connected to an external power source.

[0106] One or more batteries or power sources are in electrical communication with the ultrasonic vibrator. The ultrasonic vibrator can provide ultrasonic vibrations to the dome for generating the various forces described above. In some forms, the ultrasonic vibrator includes a portion that forms a second coupling feature of the hand unit, the second coupling feature corresponding to the first coupling feature (e.g., see Fig.13A and 13B , 1262 and 1262'). An ultrasonic vibrator suitable for this system is commercially available.

[0107] c. Circuit board and controller

[0108] The hand unit can include a circuit board electrically connected to a controller, optionally more than one controller, for starting / stopping the power supply (i.e., allowing the power to be turned on and off), adjusting the power output, adjusting the duration of cleaning, and / or adjusting the frequency and / or duration of the ultrasonic vibrations, such as by using a pump included in the base unit.

[0109] The controller may have a single function, such as controlling the start / stop of the power supply, adjusting the power output or adjusting the duration of cleaning, adjusting the frequency of ultrasonic vibration or adjusting the duration of ultrasonic vibration. Alternatively, the controller may have dual or multi-functions, such as controlling the start or stop of the power supply and adjusting the power output, adjusting the power output and the duration of cleaning, or adjusting the frequency and duration of ultrasonic vibration.

[0110] Optionally, the hand unit includes two or more controllers, each controller electrically connected to the circuit board and having one or two functions that allow the user to start / stop the power (i.e., allow the power to be turned on and off), adjust the power output, adjust the cleaning duration, and adjust the frequency and / or duration of the ultrasonic vibrations.

[0111] The circuit board and controller(s) allow the desired parameters to be manually set according to the user's needs. For example, the circuit board and controller(s) allow the user to apply a desired power output and / or vibration frequency for a desired duration.

[0112] d. Optional Features

[0113] The hand unit may have a gripping structure (e.g., knurling, ridges, rubber, etc.) to stabilize it in the user's hand. For example, the hand unit includes longitudinal ridges to record the rotation direction of the hand unit in the user's hand.

[0114] The hand unit may include an output display electrically connected to the circuit board so that certain parameters (e.g., battery life, power output, cleaning duration, ultrasonic vibration frequency, ultrasonic vibration duration, etc.) can be presented on the display. Optionally, when the system is used for a preset period of time, an audible signal may be provided indicating the end of the cleaning period.

[0115] The components included in the hand unit can be arranged in any suitable relative positions. Two specific examples of hand units are described in the examples ( Fig. 13B and 13C , 1200 and 1200'). Although Fig. 13B and 13C Not shown, but hand units 1200 and 1200' may be modified to include an output display and / or gripping features, and / or remove the battery compartment and include a cord for plugging into a power source.

[0116] 3. Base unit

[0117] The base unit of the system contains the tank, one or more tubes, a motor, a pump, and optionally a fill port, a pressure regulator, a switch, an air passage, a tube storage element, a bracket for holding additional conduits, and / or a water supply element.

[0118] a.Can

[0119] The canister has a body defined by one or more walls and a lid. The lid may be integral with the body or may be detachable from the body. Optionally, the canister includes a pharmaceutically inert port configured to add a pharmaceutical tablet or pharmaceutical solution to the canister. The pharmaceutically inert port is in fluid communication with the body and may be located at any suitable location on the canister, such as on the lid of the canister (see, e.g., Fig.12 , 1600). The body of the tank can have any shape and size, as long as its volume is sufficient to hold a liquid for rinsing teeth, such as water or an aqueous solution formulated for treating dental diseases. The tank can be detached from the base unit so that an empty tank can be replaced with a tank filled with liquid, or refilled with liquid for reuse. Optionally, the system includes a water supply element (e.g., a tube, a pipe, etc.) through which the tank is connected to a water source, such as a faucet. The water supply element is in fluid communication with the body of the tank so that water can be refilled manually or automatically through the water supply element.

[0120] b.Tube

[0121] The hand unit is connected to the liquid and / or air in the tank via one or more tubes, such that the tube(s) of the base unit are in fluid communication with channels contained in the hand unit.

[0122] For example, Fig.13A As shown, tube 1131 connects the hand unit to a first inlet 1132a of a three-way adapter 1132. Adapter 1132 has a second inlet 1132b connected to tube 1133 in fluid communication with air, and a third inlet 1132c connected to tube 1134 connected to body 1121 of tank 1120.

[0123] Thus, air from the external environment can flow into the hand unit 1200 through the air passage 1810, the tube 1133, the adapter 1132, and the tube 1131; and liquid from the tank can flow into the hand unit 1200 through the tube 1134, the adapter 1132, and the tube 1131. The adapter 1132 can include one or more valves so that the user can adjust the flow to allow air or liquid or both air and liquid to flow into the hand unit 1200.

[0124] c. Motor and pump

[0125] The base unit includes a motor, optionally more than one motor, which drives liquid and / or air from the tank and the external environment through the tubes into the hand unit.

[0126] The base unit comprises a pump, optionally more than one pump, which controls the pressure, pulse frequency and / or speed of the liquid flow, and the generation of vibrations at the dome. Optionally, the base unit also comprises a pressure regulator coupled to the pump, allowing adjustment of any of the above parameters.

[0127] Optionally, the base unit further comprises a switch electrically connected to the pump, by which the pump and / or the motor are turned on and off.

[0128] d. Charging port or stand

[0129] The base unit may include a charging port. As described above, the charging port or the cradle has a shape and size corresponding to the third coupling feature on one opposite end of the hand unit, so that the third coupling feature electrically couples to the charging port of the base unit or cooperates with the cradle of the base unit for holding the hand unit, optionally in an upright position.

[0130] e. Other components

[0131] The system may include one or more additional holders for holding one or more additional catheters disposed in the same system. Fig.13A As shown, the exemplary system 1000 includes a holder 1150 for holding an additional catheter 1500'.

[0132] The system may include a tube storage element (see, e.g., Fig.13A , 1170). A tube storage element included in the system allows for incorporation of a long tube connecting the hand unit and the base unit so that the user can operate the hand unit at various distances from the base unit.

[0133] II. How to use

[0134] Disclosed are methods of oral cleaning in a subject in need thereof using a system incorporating the domes described herein.

[0135] Typically, the method includes (i) moving the dome along the dental arch of the subject. When the dome moves along the dental arch, liquid and / or air is passed through the outlet of the socket of the dome at a pressure in the range of from about 0.5 psi to about 30 psi, from about 1 psi to about 20 psi, or from about 3 psi to about 15 psi, a pulse frequency in the range of from 0.5 Hz to about 50 Hz, from about 1 Hz to about 40 Hz, or from about 5 Hz to about 25 Hz, and / or a delivery pulse volume in the range of from about 0.1 ml to about 150 ml, from about 0.2 ml to about 120 ml, from about 0.5 ml to about 100 ml, or from about 1 ml to about 50 ml. The delivery pulse volume is the total volume of water or air ejected from the outlet of the socket at each pulse. When ultrasonic vibration is provided to the dome, the ultrasonic vibration can have a frequency of about 100 to about 5000 vibrations per second, about 500 to about 4000 vibrations per second, or about 1000 to about 3000 vibrations per second.

[0136] The liquid used in the methods described herein can be water or an aqueous solution containing one or more effective amounts of an active agent to provide the effect sought. Active agents suitable for forming an aqueous solution include, but are not limited to, detergents, antimicrobial agents, mineralizers, desensitizing agents, and whitening agents and combinations thereof. The specific concentration of the active agent or each active agent in the aqueous solution depends on the specific agent used, the disease being treated, the specific subject, and the beneficial effect sought.

[0137] Optionally, the method further includes attaching the dome to the hand unit prior to step (i); placing the dome on the subject's teeth prior to step (i); activating power to the hand unit before or after step (i); selecting or adjusting power output, cleaning duration, ultrasonic vibration frequency and / or ultrasonic vibration duration before or during step (i); maintaining the dome on the target tooth for a period of time; switching between liquid and air during step (i); and / or rinsing the mouth with mouthwash before and / or after step (i).

[0138] The disclosed devices, systems and methods of use may be further understood through the following enumerated paragraphs.

[0139] 1. A dome for removing dental plaque / oral biofilm from targeted surfaces or all surfaces of a tooth, comprising:

[0140] Wotou,

[0141] Socket ball, and

[0142] A pair of opposing wings,

[0143] The steamed bread comprises two wings connected with a membrane and a top,

[0144] wherein the top includes at least one set of opposing sides and an opening located at or near a center of the top,

[0145] wherein the two wing connecting films are bonded to the set of opposite sides of the top,

[0146] wherein the wing connecting membrane and the top form a joint housing,

[0147] The socket ball comprises a head portion and a connecting portion,

[0148] wherein the head is located within the joint housing,

[0149] wherein the connecting portion passes through the opening of the top,

[0150] Each of the double-sided wings is bonded to the proximal end of one of the wing connection membranes via a connection edge.

[0151] 2. The dome of paragraph 1, wherein each of the wing connecting membranes comprises an inner surface and an outer surface, wherein a gap is located between a majority of the surface of the socket ball and the inner surface of each of the wing connecting membranes.

[0152] 3. A dome according to paragraph 1 or 2, wherein each of the double-sided wings extends downwardly from the wing connecting membrane to which it is bonded.

[0153] 4. The dome according to any one of paragraphs 1 to 3, wherein an open area is located in a connection area connecting each of the double-sided wings and the wing connecting film to which it is bonded.

[0154] 5. The dome of any of paragraphs 1-4, wherein each of the double-sided wings comprises a cleaning membrane, a base, and two side portions, wherein the base is connected to the cleaning membrane by a bottom edge and the side portions are connected to the cleaning membrane by a pair of opposing side edges.

[0155] 6. The dome of claim 5, wherein the cleaning film of each of the double-sided wings comprises an inner surface and an outer surface, wherein the outer surface of the cleaning film of the double-sided wings has a curvature such that the double-sided wings surround each target tooth when in use.

[0156] 7. The dome of claim 6, wherein the inner surface of the cleaning film comprises a vertical plane, optionally two or more vertical planes aligned side by side, wherein the vertical plane, optionally each of the two or more vertical planes, comprises a curvature that conforms to an outer curvature of one or more types of teeth.

[0157] 8. The dome of any of paragraphs 5-7, wherein the base and each of the two side portions have a curved shape so as to be rolled away from the periodontal tissue when in use.

[0158] 9. The dome of any of paragraphs 5-8, wherein one or both of the dual wings comprises a cleaning element, optionally two or more cleaning elements, bonded to the inner surface of the cleaning membrane and / or to the bottom of the cleaning membrane.

[0159] 10. A dome according to paragraph 9, wherein the cleaning element, optionally each of the two or more cleaning elements, is a plurality of water cannons, a water cannon fold or two or more water cannon folds, a plurality of large nozzles, a plurality of micro nozzles or a plurality of water cannons coupled with a large / micro nozzle head.

[0160] 11. The dome of paragraph 10, wherein each of the plurality of water monitors comprises a hollow barrel, wherein the hollow barrel is embedded in an inner surface of the cleaning membrane creating an opening therein.

[0161] 12. The dome of paragraph 11, wherein each of the plurality of water monitors is positioned such that it is perpendicular to an outer curvature of a target tooth.

[0162] 13. The dome of paragraph 11 or 12, wherein the hollow barrel has a tapered cylindrical shape.

[0163] 14. The dome of any of paragraphs 10-13, wherein the monitor fold or each of the two or more monitor folds comprises a continuous channel along a bottom edge of the cleaning membrane.

[0164] 15. The dome of paragraph 14, wherein the channel includes an opening directed at an angle toward the periodontal pocket, wherein the channel is deep enough to capture liquid / air and / or gas bubbles when in use.

[0165] 16. The dome according to any one of paragraphs 10-15, wherein the two or more water monitor folds are arranged parallel to each other, and there is an appropriate distance between adjacent water monitor folds.

[0166] 17. The dome of any of paragraphs 10-16, wherein each macro-nozzle of the plurality of macro-nozzles and / or each micro-nozzle of the plurality of micro-nozzles comprises a hemispherical cone protruding from an inner surface of the cleaning membrane.

[0167] 18. A dome according to any of paragraphs 10-17, wherein the diameter of each of the plurality of macro-nozzles is in the range of from >1 mm to about 5 mm, from about 1.2 mm to about 5 mm, from about 1.5 mm to about 3 mm, for example, about 1.5 mm, from about 0.5 mm to about 1 mm, or from about 1 mm to about 2 mm; and the diameter of each of the plurality of micro-nozzles is in the range of from about 0.1 mm to about 1 mm, from about 0.1 mm to about 0.8 mm, or from about 0.2 mm to about 0.6 mm, for example, about 0.5 mm.

[0168] 19. A system for removing dental plaque / oral biofilm from a targeted surface or all surfaces of a tooth, comprising:

[0169] A dome according to any one of paragraphs 1 to 18,

[0170] catheter, and

[0171] Hand unit,

[0172] wherein the hand unit comprises a channel and two opposite ends,

[0173] wherein the dome is attached to one of the opposite ends of the hand unit via the conduit, and

[0174] Wherein, the channel of the hand unit is in fluid communication with a liquid and / or air source, and is in fluid communication with the conduit and the dome.

[0175] 20. The system of paragraph 19, wherein the dome is integral with or removably attached to the catheter, and / or wherein the catheter is integral with or removably attached to the hand unit.

[0176] 21. A system according to paragraphs 19 or 20, wherein the hand unit further includes a chamber for a rechargeable battery or a disposable battery, a gripping structure, an output display or audio component, or a combination thereof.

[0177] 22. A system according to any of paragraphs 19-21, wherein the hand unit further comprises an ultrasonic vibrator, a circuit board or a controller or a combination thereof.

[0178] 23. The system according to any one of paragraphs 19-22 further includes a base unit, wherein the base unit includes a tank and a tube, wherein the other opposite end of the hand unit is connected to the tank via the tube so that the channel of the hand unit is connected to the liquid fluid in the tank.

[0179] 24. The system of paragraph 23, wherein the base unit further comprises an air channel configured to be in fluid communication with the channel of the hand unit via the tube.

[0180] 25. A system according to paragraphs 23 or 24, wherein the base unit further includes a motor and pump, and optionally a pressure regulator, a power switch, a charging port, a tube storage element, a bracket for holding additional catheters, and / or a water supply element.

[0181] 26. The system of paragraph 25, wherein the base unit further comprises a power port or power cord configured to connect the system to an external power source.

[0182] 27. The system of any of paragraphs 23-26, wherein the canister comprises a body defined by one wall or two or more walls, and a lid, wherein the lid is integral with the body or removably attached to the body.

[0183] 28. The system of paragraph 27, wherein the canister further comprises a pharmaceutically inert port configured to allow a pharmaceutical tablet or a pharmaceutical solution to be added to the canister, optionally wherein the pharmaceutically inert port is located on a lid of the canister.

[0184] 29. A method of performing oral cleaning in a subject in need thereof using the system of any of paragraphs 20-28, comprising:

[0185] (i) Moving the dome along the subject's dental arch.

[0186] 30. A method according to paragraph 29, wherein during step (i), liquid and / or air is ejected through the outlet of the socket of the dome at a pressure ranging from about 0.5 psi to about 30 psi, a pulse frequency ranging from about 0.5 Hz to about 50 Hz, and / or a delivery pulse volume ranging from about 0.1 mL to about 150 mL.

[0187] 31. The method of paragraph 29 or 30, further comprising providing ultrasonic vibrations to the dome before and / or during step (i), wherein the frequency of the ultrasonic vibrations is in the range of about 100 to about 5000 vibrations per second, about 500 to about 4000 vibrations per second, or about 1000 to about 3000 vibrations per second.

[0188] 32. The method of any one of paragraphs 29-31, further comprising attaching the dome to the catheter and / or hand unit before step (i); placing the dome on the subject's teeth before step (i); activating a power source of the hand unit before or after step (i); selecting or adjusting power output, cleaning duration, ultrasonic vibration frequency and / or ultrasonic vibration duration before or during step (i); maintaining the dome on the target tooth for a period of time; switching between liquid and air during step (i); and / or rinsing the mouth with mouthwash before and / or after step (i).

[0189] The invention will be further understood by reference to the following non-limiting examples.

[0190] Example

[0191] A. Exemplary Domes

[0192] Figures 1A-1F , 2A-2B, 3A-3D, 4 and 5A-5D show different views of exemplary domes 100 and 100", which can be attached to the hand unit via catheter 1500.

[0193] like Figure 1A As shown, the dome 100 includes a socket head 110, a socket ball 130, and two double side wings 120a and 120b. Figure 2A As shown, the socket head includes two wing connecting membranes 114a and 114b and a top 116, which together form a joint housing 111. The size and shape of the joint housing 111 are such that it mates with the socket ball 130. The two wing connecting membranes 114a and 114b are on a second set of opposite sides of the top. The top 116 includes an opening 117 located at or near the center of the top. The opening is a shaped hole, such as a circular hole, which is configured to mate with the connection portion 131 of the socket ball 130. The opening can be of such a size that the top contacts the connection portion of the socket ball (see, for example, Figure 1A ), or there is a gap between the top of the wotou and the wotou ball (see, for example, Figure 1C, gap 163). The head 133 of the socket ball 130 is detachably mounted in the joint housing 111, and the connecting portion 131 passes through the opening 117 on the top 116 for connection with the catheter 1500 to form a ball-and-socket joint 160 (also referred to herein as a "spherical joint"). The connecting portion can have any suitable shape and size, as long as it corresponds to the shape and size of the opening on the top of the socket head so that it can pass through the opening and connect to the catheter. The gap 161a or 161b is located between most of the surface area of ​​the socket ball 130 and the inner surface of each wing connecting membrane 114a and 114b to allow movement of the socket ball and / or wing connecting membrane so that the socket ball 130 can rotate and move within the joint housing 111, thereby allowing liquid / air to be properly delivered to the target surface or all surfaces of the target tooth for cleaning. For example, the head 133 of the socket ball 130 can be positioned to be inclined at a certain angle relative to the central axis of the dome 100 to the inner surface of one of the bilateral wings 120a and 120b. The angle may be approximately 0 to 60 degrees, or approximately 30 degrees, depending on the location of the target surface of the target tooth.

[0194] The socket 130 includes a liquid / air channel 132 extending through the central axis of the socket, which has an outlet 134, and the outlet 134 is fluidly connected to the conduit 1500, so that water and / or air are provided to the liquid / air channel 132 through the conduit 1500 and then rinsed through the outlet 134 to the target surface or all surfaces of the target teeth (e.g., lips / cheeks, tongue, interdental spaces, gingival sulci and / or periodontal pockets).

[0195] The proximal end 113a or 113b of each wing connecting film 114a and 114b is bonded to the wing 120a or 120b extending downward from each film by a suitable technique, such as thermal bonding. Optionally, the wing connecting film 114a (or 114b) and the wing 120a (or 120b) are integral pieces (i.e., single-piece structures). The triangular open area 140a or 140b is located in the connecting area 115a or 115b connecting the wing 120a or 120b and the wing connecting film 114a or 114b. The open area 140a or 140b is configured to allow movement of the wing so that the angle between the imaginary vertical measurement line 171 (which is aligned with the central vertical axis of the socket) and each wing 120a and 120b can change during ultrasonic vibration and / or adapt to teeth of different sizes. Although not shown, the open area can have any suitable shape and size, such as a rectangle, square, trapezoid, a cut line, etc. As long as it is located in the connection area and allows the movement of the wing. Figure 2A and 2B As shown, each of the two side wings 120a and 120b forms a first angle α1 with an imaginary vertical measurement line 171 to accommodate one or more incisors and canines ( Figure 2A), or form a second angle α2 with the imaginary vertical measurement line 171 to accommodate one or more premolars and molars ( Figure 2B ). The second angle α2 is greater than the first angle α1 because the width of the premolars and molars is greater than that of the incisors and canines.

[0196] like Figure 3A As shown, each double wing comprises a cleaning film 121 having an inner surface 123 and an outer surface 125 (in Figure 3A Not visible in ; see e.g. Figure 5B ), base 127 (at Figure 3A Not visible in ; see e.g. Figure 5B ), and two side portions 129a and 129b (at Figure 3A Not visible in ; see e.g. Figure 5B ).like Figure 5B As shown, the base 127 is connected to the cleaning film 121 through the bottom edge 175; the side portions 129a and 129b are connected to the cleaning film 121 through a pair of opposite side edges 177a and 177b respectively; and the cleaning film 121 is connected to the wing connecting film of the wotou through the connecting edge 173. The connecting edge 173, the bottom edge 175 and the two side edges 177a and 177b define the length (L) and width (W) of each wing. The length L is measured from the connecting edge 173 to the bottom edge 175. The width W is measured from the first side edge 177a to the second side edge 177b. The length (L) and width (W) of each wing are sufficient to cover the labial / buccal and lingual surfaces of the teeth, for example, the length (L) is in the range of about 10 mm to about 20 mm, optionally in the range of about 10 mm to about 18 mm or from about 10 mm to about 16 mm, for example about 11 mm, and the width (W) is in the range of about 5 mm to about 25 mm, optionally in the range of about 5 mm to about 20 mm, from about 10 mm to about 20 mm, or from about 5 mm to about 8 mm, for example about 6 mm or 18 mm. The distance between the bottom edges of the wings can be from about 5 mm to about 25 mm, from about 5 mm to about 20 mm, from about 5 mm to 15 mm, or from about 5 mm to 10 mm. The distance between the inner surface 123 and the outer surface 125 defines the thickness (T) of each wing. The thickness T of each wing is sufficient to incorporate one or more cleaning elements on the inner surface, as described in detail below.

[0197] The outer surface 125 of each wing has a curvature so that the two wings surround each target tooth. Typically, the outer surface 125 is smooth to minimize irritation to the oral cavity during operation. Optionally, the outer surface 125 can be configured to mirror the inner surface 123 of each cleaning film 121 so that the user can select the correct dome to use. The inner surface 123 of each cleaning film 121 includes one or more vertical planes, such as two vertical panels 122, 124 aligned side by side. Each panel includes a curvature consistent with the external curvature of a type of tooth (e.g., a premolar / molar or an incisor / canine). Each panel 122 and 124 includes a curvature 182 consistent with the external curvature of a premolar / molar; a curvature 184 consistent with the buccal curvature of an incisor / canine; or a curvature 186 consistent with the lingual curvature of an incisor / canine. Figure 3B-3D The dashed lines in the figure show the different curvatures on the inner surface of the cleaning film from the side, which correspond to the outer curvatures of the premolars / molars ( Figure 3B ), buccal curvature of incisors / canines ( Figure 3C ) and the lingual curvature of the incisors / canines ( Figure 3D ) are consistent.

[0198] The different curvatures 182, 184, and 186 on the inner surface of the cleaning film allow the bilateral wings to conform to the different curvatures of all types of human teeth. As the dome moves along the dental arch, at least one panel on each wing contains a curvature that conforms to the buccal and lingual curvature of each tooth. Figure 4 As shown, when in use, water and bubbles rush out from the outlet 134 of the socket 130, creating two interface micro-gaps: a first interface micro-gap 191 between the labial / cheek surface 301 of the treated tooth (also referred to herein as the "target tooth") and its corresponding curvature on the inner surface of the cleaning film, and a second interface micro-gap 192 between the lingual surface 302 of the tooth and its corresponding curvature on the inner surface of the cleaning film. "Corresponding curvature" refers to the curvature on the inner surface of the cleaning film, which is consistent with the outer surface (labial / cheek or lingual) of the target tooth. The interface micro-gaps 191 and 192 between the outer surface of the target tooth and their corresponding wing curvatures can guide liquid / air and / or bubbles to rush through these micro-gaps through the hydrofoil effect, and rush to the gingival sulcus (e.g., the depression under the gum line) and / or the tomography of the periodontal pocket to separate and rinse away the oral biofilm. Optionally, when ultrasonic vibration is applied, these micro-gaps also allow ultrasonic vibration waves to be emitted in a vertical direction toward the surface of the target tooth to separate the oral biofilm. Each tooth is treated in turn as the dome moves along the dental arch from the left posterior molar to the right posterior molar.

[0199] like Figure 1A-1BAs shown in FIGS. 5A-5D , the base 127 and each of the two side portions 129a and 129b of the wing have a curved shape so that as the dome moves along the dental arch, it rolls away from the periodontium to minimize any traumatic effects on the periodontium. Figure 5A As shown, instead of pointing toward the periodontium and creating a sharp contact edge with the periodontium when in use (dashed line), the base 127 of the wing has an OMEGA shape (solid line) that rolls outward from the periodontium and provides a smooth contact edge with the periodontium. Figure 5B A perspective view of the base 127 is shown, illustrating the OMEGA shape along the entire width of the wing, extending from a first side edge 177a to an opposing second side edge 177b. Figure 5C A focused side view of the base is shown, showing the OMEGA shaped base 127, which rolls outward and upward from the bottom edge 175 connected to the cleaning film 121 (the cleaning film is Figure 5C ). Figure 1A and 1B As shown, each of the two side portions 139a and 139b on each wing is rolled outward and inward from the side edge 177a or 177b, and is connected to the cleaning film 121 by the side edge 177a or 177b. The distal end of each side portion (i.e., 139a or 139b) is located at a distance D1 (measured from an imaginary horizontal measurement line Lm1 passing through the center of the opening 117) that is greater than the distance D2 (measured from the horizontal imaginary measurement line Lm1 to the inner surface of the cleaning film 121), so that the side edge of each wing does not contact the periodontal tissue at any sharp point. Figure 5D A focused bottom view of the side portion 129a (or 129b) is shown, showing the OMEGA-shaped side portion 129a (or 129b) rolled outward and inward from the side edges.

[0200] Figures 6A-6C The different curvatures (i.e., 282, 284, and 286) on the inner surface 223 of the exemplary dome 200 are shown, each having a plurality of water monitors coupled thereto connected to nozzle tips, which are collectively referred to as 290. Fig. 7AAs shown, each of the plurality of water cannons coupled to the nozzle head 290 includes a hollow barrel 291 and a nozzle head 292, wherein the hollow barrel 291 is embedded in the inner surface of the cleaning membrane, an opening 293 is created on the hollow barrel 291, and the nozzle head 292 surrounds the opening 293 of the barrel. The nozzle head 292 can be a micro nozzle head (with a diameter ranging from 0.1 mm to 2 mm, or from about 1 mm to about 2 mm) or a large nozzle head (with a diameter ranging from 1 mm to 5 mm, or from about 2 mm to about 3 mm), which protrudes slightly above the inner surface of the cleaning membrane. The hollow barrel 291 is positioned perpendicular to the corresponding curvature so that it is also perpendicular to the outer curvature of the target tooth, such as the outer curvature of the premolar / molar ( Fig. 6A ), labial surface of premolars / molars ( Figure 6B ), or the lingual surface of the incisors / canines ( Figure 6C ). The hollow barrel 291 has a depth (d1) (measured from the opening 293 to the bottom 294 of the barrel) sufficient to capture liquid / air and / or bubbles in the outer surface of the target tooth when in use, and then eject the captured liquid / air and / or bubbles toward the outer surface of the target tooth. The depth (d1) of the barrel can be adjusted to obtain the desired force, ejection distance and direction of the target tooth.

[0201] In use, liquid / air and / or ultrasonic vibrations are flushed / applied to the dome; water cannons coupled to nozzle heads 290 on the inner surface of each wing can generate (1) cavitation forces generated by the collapse of bubbles that release energy to create suction on the biofilm ( Figure 7B ), (2) water cannon force generated by capturing and ejecting liquid / air and / or bubbles in a bouncing mode triggered by ultrasonic vibrations ( Figure 7C ), and / or (3) radial tsunami forces promoted by the nozzle tip ( Fig.7D ).

[0202] Figure 8A perspective view of one side of an exemplary dome 300 is shown, the dome 300 having a cannon fold 395 bonded to the inner surface 323 of the cleaning film 321 of the wing 320a. The cannon fold 395 is a continuous channel located above and along the bottom edge 375 of the wing 320a. The channel can have any suitable shape, such as a trapezoid, a cone, a semi-cylindrical, a hemispherical, etc. The cannon fold 395 extends from a first side edge 377a of the wing 320a to an opposite second side edge 377b. The cannon fold 395 has an opening 399 directed at a certain angle toward the periodontal pocket, and a depth (d2) measured from the opening 399 to the bottom 391 of the channel. The depth (d2) of the water cannon fold is sufficient to capture liquid / air and / or bubbles so that when ultrasonic vibration is applied, the water cannon fold 395 can capture liquid / air and / or bubbles and then eject the captured liquid / air and / or bubbles toward the gingival sulcus and / or periodontal pocket. The depth (d2) of the water cannon fold can be adjusted to obtain the desired force, ejection distance and direction of the target tooth. For example, the d2 of the exemplary water cannon fold 395 is in the range of from about 2 mm to about 3 mm. The dome 300 has two features for effectively removing biofilm in the periodontal pocket: (1) liquid / air and / or bubbles rush to the gingival sulcus (e.g., depression under the gum line) and / or the tomography of the periodontal pocket via the hydrofoil effect through the interface micro-gap, and (2) liquid / air and / or bubbles are ejected from the water cannon fold toward the periodontal pocket.

[0203] Fig. 9A A perspective view of one side of an exemplary dome 400 is shown having three monitor folds 495, 496 and 497 bonded to the cleaning membrane 421 of wing 420a. Fig. 9B A side view of a double wing 420a and 420b is shown, each wing including three cannon folds 495, 496 and 497. The three cannon folds 495, 496 and 497 are arranged parallel to each other on the inner surface of the cleaning film, with a distance (i.e., d3a, d3b) between adjacent cannon folds. The first distance d3a may be the same or different from the second distance d3b. Each of the cannon folds 495, 496 and 497 has an opening directed toward the gingival sulcus, periodontal pocket and / or gingival implant interface.

[0204] Fig. 10A A perspective view of one side of an exemplary dome 500 having a plurality of micro-nozzles, generally referred to as 591 , bonded to an inner surface 523 of a cleaning membrane 521 is shown. Fig. 10BA side view of two double-sided wings 520a and 520b is shown, each of which incorporates a plurality of micro-nozzles 591 on the inner surface of the cleaning film. Each of the plurality of micro-nozzles 591 is a hemispherical cone protruding from the inner surface 523 of the cleaning film. When used, these micro-nozzles 591 can generate free radical tsunami waves in all directions toward the outer surface of the target tooth to separate the oral biofilm by shear force (see, e.g. Fig. 7E ).

[0205] Figures 11A-11C A cross-sectional view of exemplary domes 600, 700, and 800 is shown, showing one wing of each dome having different cleaning elements bonded to the inner surface of the cleaning membrane. Fig.11A As shown, dome 600 includes a plurality of micro nozzles 691 and a water cannon fold 695 bonded to the inner surface of the cleaning membrane. Fig. 11B As shown, dome 700 includes a plurality of large nozzles 791 and cannon folds 795 incorporated into the inner surface of the cleaning membrane. Fig. 11C As shown, dome 800 includes a plurality of water monitors coupled to nozzle heads 891 and water monitor folds 895 incorporated into the inner surface of the cleaning membrane. Figures 11A-11C Not shown, the other wing of dome 600, 700 or 800 may have the same or different cleaning elements, or no cleaning elements bonded to the inner surface of its cleaning film. If the other wing of each dome has the same cleaning elements bonded to the inner surface of its cleaning film, the number or arrangement of the cleaning elements may be the same as above. Figures 11A-11C Same or different on wings as shown.

[0206] B. Exemplary Systems

[0207] Fig.12 and 13A -13C shows an exemplary system incorporating a dome for oral cleaning.

[0208] like Fig.13AAs shown, the exemplary system 1000 includes a base unit 1100, a hand unit 1200, a catheter 1500, and a dome 100'. The dome 100' is attached to the hand unit 1200 via the catheter 1500. The dome 100' can have any of the structures of the exemplary domes 100-800 described above. The catheter 1500 has two opposing ends 1510 and 1520. The dome 100' is attached to the first opposing end 1510 of the catheter 1500 by any suitable coupling mechanism, such as heat sealing, stabilization, assembly, threaded connection, or any other suitable mechanical connection. Optionally, the connection portion 131' of the dome 100' is integral with or attached to the first opposing end 1510 of the catheter 1500, so that the dome and the catheter are a one-piece component or two separate components. The second opposite end 1520 of the conduit 1500 includes a first coupling feature 1530, such as a female or male plug feature, which can be coupled to a second coupling feature 1230 of the hand unit 1200, the second coupling feature 1230 corresponding to the first coupling feature 1530, such as a male or female plug feature. The hand unit 1200 has two opposite ends 1210 and 1220. The first opposite end 1210 of the hand unit includes a second coupling feature 1230 corresponding to the first coupling feature 1530 of the conduit; the second opposite end 1220 of the hand unit is combined with a third coupling feature 1240 corresponding to the charging port 1110 of the base unit. The third coupling feature 1240 can have any suitable shape and size, such as a recess, as long as it can be electrically coupled to the charging port 1110 of the base unit.

[0209] The base unit 1100 includes a tank 1120, one or more tubes (collectively referred to as 1130), a tube storage element 1170, a motor 1140, a bracket 1150 for holding an additional catheter 1500', and a water supply element 1160. The tank 1120 has a body 1121 and a lid 1122. The body 1121 of the tank has a volume sufficient to hold a liquid for rinsing the teeth, such as water or an aqueous solution formulated to treat a dental condition. The tank 1120 can be removed from the base unit so that the empty container can be replaced with a container filled with liquid, or refilled with liquid for reuse. Optionally, the tank 1120 is connected to a water / medication source via a water / medication supply port 1160; the supply port 1160 is in fluid communication with the body 1121 of the tank so that the water / medication can be manually or automatically refilled through the supply port. The hand unit 1200 is connected to the liquid and air in the tank via one or more tubes 1130. As Fig.13AAs shown, tube 1131 connects the hand unit to a first inlet 1132a of a three-way adapter 1132. Adapter 1132 has a second inlet 1132b connected to tube 1133 in fluid communication with air, and a third inlet 1132c connected to tube 1134, which is connected to the body 1121 of the tank 1120. Thus, air from the external environment can flow into the hand unit 1200 through tube 1133, adapter 1132, and tube 1131; liquid from the tank can flow into the hand unit 1200 through tube 1134, adapter 1132, and tube 1131. Adapter 1132 may include one or more valves so that a user can adjust the flow to allow air or liquid or both air and liquid to flow into the hand unit 1200. Tube storage element 1170 allows the incorporation of a long tube connecting the hand unit and the base unit so that the hand unit can be used at various distances from the base unit. The motor 1140 drives the liquid and / or air from the container and the external environment to flow into the hand unit through the pipe.

[0210] like Fig. 13B As shown, the hand unit 1200 includes a channel 1240 for liquid / air to flow through, a battery chamber 1250 for accommodating a rechargeable battery or a disposable battery, an ultrasonic vibrator 1260, a circuit board 1270, and a controller 1280. The channel 1240 is connected to the tube 1131. The conduit 1500 is coupled to the hand unit 1200 via the coupling features 1530 and 1230 as described above, and is in fluid communication with the channel 1240. The dome 100' is integrated with the conduit 1500 to form a single piece. This configuration allows liquid and / or air to flow from the base unit through the tube into the channel in the hand unit, then into the conduit, reach the dome, and flow to the target tooth through the interface micro-gap. Fig. 13C An alternative form of hand unit 1200' is shown, which includes a channel 1240', a battery chamber 1250', an ultrasonic vibrator 1260', a circuit board 1270', and a controller 1280', which are arranged differently from the components in hand unit 1200. For example, channel 1240 in hand unit 1200 is located along a side 1293 of the hand unit, extending from a top edge 1291 of the hand unit to a bottom edge 1292 (see FIG. 1 ). Fig. 13B ). A channel 1240' in the hand unit 1200' is sandwiched between the ultrasonic vibrator 1260' and the circuit board 1270' and extends from the top edge 1251' of the battery chamber 1250' to a point 1241' aligned with the top edge 1261' of the ultrasonic vibrator. Although Fig. 13B and 13C Not shown, but hand units 1200 and 1200' may be modified to include an output display, and / or remove the battery compartment and include a cord for plugging into a power source.

[0211] Fig.12 An alternative embodiment of system 1000' is shown, which includes base unit 1100', hand unit 1200', conduit 1500' and dome 100". Dome 100" is removably connected to hand unit 1200' via conduit 1500'. The hand unit is in fluid communication with tank 1120' of base unit 1100' via conduit 1130'. The components and configuration of the base unit are different from those in system 1000. For example, in addition to tank 1120', conduit 1130' and motor ( Fig.12 ), the base unit 1100' also includes a pump, a switch, and an optional pressure regulator (all of which are in Fig.12 The pump controls the pressure, pulse frequency and / or speed of the liquid flow, and the generation of vibrations at the dome. When the pump is coupled to a pressure regulator in the system, these operating parameters can be adjusted according to the needs of the user. A switch contained in the base unit is electrically connected to the pump, allowing the pump and / or motor to be turned on and off. The tank 1120' includes a medication inlet port 1600 located on the tank lid to allow the user to add medication tablets or liquids to the liquid in the tank. In addition, the base unit 1100' may include a power plug or power cord, which includes a power plug to allow the system to be electrically connected to an external power source 1800 to provide sufficient power to the system.

Claims

1. A dome for removing dental plaque / oral biofilm from targeted surfaces or all surfaces of a tooth, comprising: Steamed bread, Socket ball, and A pair of opposing wings, The steamed bread comprises two wings connected with a membrane and a top. wherein the top includes at least one set of opposing sides and an opening located at or near the center of the top, wherein the two wing connecting films are bonded to the set of opposite sides of the top, wherein the wing connection membrane and the top form a joint housing, Wherein, the socket ball comprises a head portion and a connecting portion, wherein the head is located in the joint housing, Wherein, the connecting portion passes through the opening of the top, Each of the double-sided wings is bonded to the proximal end of one of the wing connecting films via a connecting edge.

2. The dome according to claim 1, wherein: Each of the wing connecting membranes includes an inner surface and an outer surface, wherein a gap is located between a majority of the surface of the socket ball and the inner surface of each of the wing connecting membranes.

3. The dome according to claim 1 or 2, wherein: Each of the double-sided flaps extends downwardly from the flap connecting film to which it is bonded.

4. The dome according to any one of claims 1 to 3, wherein: The open area is located in the connection area connecting each of the double-sided wings and the wing connection film bonded thereto.

5. The dome according to any one of claims 1 to 4, wherein: Each of the double-sided wings comprises a cleaning film, a base and two side portions, wherein the base is connected to the cleaning film by a bottom edge and the side portions are connected to the cleaning film by a pair of opposing side edges.

6. The dome according to claim 5, wherein: Each of the cleaning films of the double-sided wings comprises an inner surface and an outer surface, wherein the outer surface of the cleaning film of the double-sided wings has a curvature, so that the double-sided wings surround each target tooth when in use.

7. The dome according to claim 6, wherein: The inner surface of the cleaning film comprises a vertical plane, optionally two or more vertical planes aligned side by side, wherein the vertical plane, optionally each of the two or more vertical planes, comprises a curvature that conforms to an outer curvature of one or more types of teeth.

8. The dome according to any one of claims 5 to 7, wherein: The base and each of the two side portions have a curved shape so as to be rolled away from the periodontal tissue when in use.

9. The dome according to any one of claims 5 to 8, wherein: One or both of the dual wings comprise a cleaning element, optionally two or more cleaning elements, which are bonded to the inner surface of the cleaning membrane and / or to the bottom of the cleaning membrane.

10. The dome according to claim 9, wherein: The cleaning element, optionally each of the two or more cleaning elements, is a plurality of water cannons, a water cannon folding portion or two or more water cannon folding portions, a plurality of large nozzles, a plurality of micro nozzles or a plurality of water cannons coupled with a large / micro nozzle head.

11. The dome according to claim 10, wherein: Each of the plurality of water monitors includes a hollow barrel, wherein the hollow barrel is embedded in an inner surface of the cleaning membrane, creating an opening therein.

12. The dome according to claim 11, wherein: Each water cannon of the plurality of water cannons is positioned such that it is perpendicular to an outer curvature of a target tooth.

13. A dome according to claim 11 or 12, wherein: The hollow barrel has a tapered cylindrical shape.

14. The dome according to any one of claims 10 to 13, wherein: The monitor fold or each of the two or more monitor folds comprises a continuous channel along a bottom edge of the cleaning membrane.

15. The dome according to claim 14, wherein: The channel comprises an opening directed at an angle towards the periodontal pocket, wherein the channel is deep enough to capture liquid / air and / or gas bubbles when in use.

16. The dome according to any one of claims 10 to 15, wherein: The two or more water monitor folding parts are arranged parallel to each other, and there is an appropriate distance between adjacent water monitor folding parts.

17. The dome according to any one of claims 10 to 16, wherein: Each of the plurality of macro-nozzles and / or each of the plurality of micro-nozzles includes a hemispherical cone protruding from an inner surface of the cleaning film.

18. The dome according to any one of claims 10 to 17, wherein The diameter of each of the multiple large nozzles is in the range of from >1mm to about 5mm, from about 1.2mm to about 5mm, from about 1.5mm to about 3mm, for example, about 1.5mm, from about 0.5mm to about 1mm, or from about 1mm to about 2mm; the diameter of each of the multiple micro nozzles is in the range of from about 0.1mm to about 1mm, from about 0.1mm to about 0.8mm, or from about 0.2mm to about 0.6mm, for example, about 0.5mm.

19. A system for removing dental plaque / oral biofilm from a targeted surface or all surfaces of a tooth, comprising: The dome according to any one of claims 1 to 18, catheter, and Hand unit, Wherein, the hand unit comprises a channel and two opposite ends, wherein the dome is attached to one of the opposite ends of the hand unit via the conduit, and Wherein, the channel of the hand unit is in fluid communication with a liquid and / or air source, and is in fluid communication with the conduit and the dome.

20. The system of claim 19, wherein: The dome is integral with the conduit or is removably attached to the conduit and / or wherein the conduit is integral with the hand unit or is removably attached to the hand unit.

21. The system according to claim 19 or 20, wherein: The hand unit also includes a chamber for a rechargeable battery or a disposable battery, a gripping structure, an output display or audio component, or a combination thereof.

22. The system according to any one of claims 19 to 21, wherein: The hand unit further includes an ultrasonic vibrator, a circuit board or a controller or a combination thereof.

23. The system according to any one of claims 19-22, further comprising a base unit, wherein the base unit comprises a tank and a tube, wherein the other opposite end of the hand unit is connected to the tank via the tube so that the channel of the hand unit is in fluid communication with the liquid in the tank.

24. The system of claim 23, wherein: The base unit also includes an air channel configured to be in fluid communication with the channel of the hand unit via the tube.

25. A system according to claim 23 or 24, wherein: The base unit also includes a motor and pump, and optionally a pressure regulator, a power switch, a charging port, a tube storage element, a holder for holding additional tubing, and / or a water supply element.

26. The system of claim 25, wherein: The base unit also includes a power port or power cord configured to connect the system to an external power source.

27. The system according to any one of claims 23 to 26, wherein: The can includes a body defined by one wall or two or more walls, and a lid, wherein the lid is integral with the body or detachably attached to the body.

28. The system of claim 27, wherein: The canister further comprises a pharmaceutically inert port configured to allow a pharmaceutical tablet or a pharmaceutical solution to be added to the canister, optionally wherein the pharmaceutically inert port is located on a lid of the canister.

29. A method of performing oral cleaning in a subject in need thereof using the system of any one of claims 20-28, comprising: (i) Moving the dome along the subject's dental arch.

30. The method of claim 29, wherein during step (i), liquid and / or air is ejected through the outlet of the dome's socket at a pressure in the range of from about 0.5 psi to about 30 psi, a pulse frequency in the range of from about 0.5 Hz to about 50 Hz, and / or a delivery pulse volume in the range of from about 0.1 mL to about 150 mL.

31. The method of claim 29 or 30, further comprising providing ultrasonic vibrations to the dome prior to and / or during step (i), wherein the frequency of the ultrasonic vibrations is in the range of about 100 to about 5000 vibrations per second, about 500 to about 4000 vibrations per second, or about 1000 to about 3000 vibrations per second.

32. The method according to any one of claims 29-31 further includes attaching the dome to the catheter and / or hand unit before step (i); placing the dome on the subject's teeth before step (i); activating the power supply of the hand unit before or after step (i); selecting or adjusting the power output, cleaning duration, ultrasonic vibration frequency and / or ultrasonic vibration duration before or during step (i); maintaining the dome on the target tooth for a period of time; switching between liquid and air during step (i); and / or rinsing the mouth with mouthwash before and / or after step (i).

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