Measuring equipment and measuring method for brain function nuclear magnetic imaging during resistance respiration, model construction method and electronic equipment

By obtaining resistance breathing data with the combination of nuclear magnet and breathing trainer, and combining model construction methods, the problem of complex and inaccurate data in the existing technology is solved, and accurate resistance breathing data acquisition and Data matching provides effective tools for studying dyspnea.

CN119279558APending Publication Date: 2025-01-10BEIJING CHAOYANG HOSPITAL CAPITAL MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202411440234.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-15
Publication Date
2025-01-10

AI Technical Summary

Technical Problem

In the prior art, the dyspnea perception and determination instruments are complex and the data are not accurate enough, making it difficult to effectively study the processing of dyspnea in neuromodulation and neuroimaging.

Method used

A measurement device for brain function nuclear magnetic imaging during resistance breathing is designed, including a nuclear magnet, a breathing mask, a pipeline and a breathing trainer. The brain function imaging is performed through a nuclear magnet, and respiratory resistance data are obtained through pressure changes in the pipeline. In combination with model construction methods, feature data were collected and matched to construct models of resistance respiration and brain function nuclear magnetic imaging.

Benefits of technology

It realizes accurate acquisition of resistance breathing data under NMV conditions, improves the accuracy of dyspnea perception and data matching accuracy of dyspnea perception and measurement methods, and provides convenient tools for studying neuromodulation and emotional distress of dyspnea.

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Abstract

The invention provides a measuring device and method for brain function nuclear magnetic imaging during resistance respiration, a model construction method, a storage medium and electronic equipment, and the measuring device comprises a nuclear magnetic instrument which is located in a nuclear magnetic resonance chamber and is used for performing nuclear magnetic imaging on brain functions of a testee; the breathing mask is mounted on the nuclear magnetic instrument; one end of the pipeline is communicated with the breathing mask; the breathing training instrument is located outside the nuclear magnetic resonance chamber, the breathing training instrument is communicated with the other end, penetrating through the wall of the nuclear magnetic resonance chamber, of the pipeline, when a testee breathes, the pressure in the pipeline changes, the breathing training instrument senses the pressure change in the pipeline, and breathing resistance data is obtained. According to the measuring equipment, on the premise that nuclear magnetism compatibility is achieved, accurate resistance respiration data are guaranteed.
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Description

Technical Field

[0001] The present invention relates to the technical fields of software engineering, big data, distributed storage and computing, and more specifically, to a measuring device, a measuring method, a model building method, a storage medium and an electronic device for brain functional magnetic resonance imaging during resistive breathing. Background Art

[0002] Dyspnea is a common and distressing symptom of cardiopulmonary and neuromuscular diseases. It is generally believed that sensory information from the respiratory system activates cortical areas of the brain, producing the sensation of dyspnea. However, further research is urgently needed on the neuromodulation, neuroimaging, and central processing of the dyspnea sensation, as well as the associated discomfort and emotional distress, to meet the research needs of cardiopulmonary, neurological diseases and sports medicine.

[0003] Although there are a few instruments or systems for measuring dyspnea perception in the industry, the various measurement methods are complex and the data are not accurate enough. Summary of the invention

[0004] One object of the present invention is to provide a new technical solution for a device for measuring brain functional magnetic resonance imaging during resistive breathing, which can solve at least one of the technical problems in the prior art that there are only a few measuring instruments or systems for sensing dyspnea, various measuring methods are complicated, and the data are not accurate enough.

[0005] Another object of the present invention is to provide a method for measuring brain functional magnetic resonance imaging and respiratory resistance data, based on the above-mentioned brain functional magnetic resonance imaging measurement equipment during resistance breathing.

[0006] Another object of the present invention is to provide a method for constructing a model of a measuring device based on brain functional magnetic resonance imaging during resistance breathing.

[0007] Another object of the present invention is to provide a computer storage medium comprising one or more computer instructions, wherein the one or more computer instructions implement the above method when executed.

[0008] Another object of the present invention is to provide an electronic device, comprising a memory and a processor, wherein the memory is used to store one or more computer instructions, and the processor is used to call and execute the one or more computer instructions, thereby implementing the above method.

[0009] According to a first aspect of the present invention, there is provided a device for measuring brain functional magnetic resonance imaging during resistive breathing, comprising: a magnetic resonance instrument, which is located in a magnetic resonance imaging room and is used to perform magnetic resonance imaging of the brain function of a subject; a breathing mask, which is installed on the magnetic resonance instrument; a pipeline, one end of which is connected to the breathing mask; and a breathing trainer, which is located outside the magnetic resonance imaging room and is connected to the other end of the pipeline passing through the wall of the magnetic resonance imaging room. When the subject breathes, the pressure in the pipeline changes, and the breathing trainer senses the pressure change in the pipeline to obtain breathing resistance data.

[0010] Optionally, a breathing valve is provided at a position on the breathing mask connected to the pipeline.

[0011] Optionally, a fixing strap is provided on the breathing mask to fix the breathing mask to the head of the test subject.

[0012] According to a second aspect of the present invention, there is provided a method for measuring functional brain magnetic resonance imaging during resistance breathing according to any of the above-mentioned measuring devices, comprising the following steps: fixing a breathing tube mask on the face of a subject; obtaining functional brain magnetic resonance imaging of the subject through a magnetic resonance imaging device; and testing the pressure change in a pipe connected to the breathing tube mask through a breathing training device to obtain respiratory resistance data.

[0013] According to a third aspect of the present invention, there is provided a method for constructing a model of a measuring device based on functional brain magnetic resonance imaging during resistance breathing, comprising the following steps: collecting characteristic data during resistance breathing training and functional brain magnetic resonance imaging data, wherein the characteristic data includes resistance breathing training data; matching the characteristic data with the functional brain magnetic resonance imaging data to obtain a data sample; and constructing a model based on resistance breathing training and functional brain magnetic resonance imaging according to the data sample.

[0014] Optionally, the characteristic data also includes personal information of the test subject, and the personal information of the test subject includes at least one of gender, date of birth, height, weight and disease information.

[0015] Optionally, the model construction method of the measurement equipment based on brain functional magnetic resonance imaging during resistance breathing also includes the following steps: collecting resistance breathing parameters and brain functional magnetic resonance imaging parameters during resistance breathing training; detecting the breathing training data based on the resistance breathing parameters; and detecting the brain functional magnetic resonance imaging data based on the brain functional magnetic resonance imaging parameters.

[0016] Optionally, the resistance breathing parameters include at least one of the inhalation and / or exhalation pattern of resistance breathing, the resistance value of resistance breathing, and the number of breaths of resistance breathing; the brain functional magnetic resonance imaging parameters include at least one of magnetic resonance structural images and magnetic resonance BOLD sequences.

[0017] According to a fourth aspect of the present invention, there is provided a computer storage medium comprising one or more computer instructions, wherein the one or more computer instructions implement any of the above-described model building methods when executed.

[0018] According to a fifth aspect of the present invention, there is provided an electronic device, comprising a memory and a processor, wherein the memory is used to store one or more computer instructions, and the processor is used to call and execute the one or more computer instructions, thereby implementing any of the above-mentioned model building methods.

[0019] The device for measuring brain functional magnetic resonance imaging during resistive breathing according to the embodiment of the present invention can ensure accurate resistive breathing data under the premise of magnetic resonance compatibility by using a magnetic resonance imaging device, a breathing mask, a pipeline and a breathing training device in combination.

[0020] Further features and advantages of the present invention will become apparent from the following detailed description of exemplary embodiments of the present invention with reference to the attached drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate embodiments of the invention and, together with the description, serve to explain the principles of the invention.

[0022] Figure 1 It is a schematic diagram of a device for measuring brain functional magnetic resonance imaging during resistance breathing according to an embodiment of the present invention;

[0023] Figure 2 is a flow chart of a model building method according to an embodiment of the present invention;

[0024] Figure 3 is a working principle diagram of an electronic device according to an embodiment of the present invention.

[0025] Reference numerals:

[0026] Device for measuring brain functional magnetic resonance imaging during resistance breathing 100;

[0027] Nuclear magnetic resonance apparatus 10; breathing mask 20; pipeline 30; breathing training apparatus 40;

[0028] Processor 201;

[0029] Memory 202; operating system 2021; application program 2022;

[0030] Network interface 203; input device 204; hard disk 205; display device 206;

[0031] MRI room 300;

[0032] 400 test subjects. DETAILED DESCRIPTION

[0033] Various exemplary embodiments of the present invention will now be described in detail with reference to the accompanying drawings. It should be noted that the relative arrangement of components and steps, numerical expressions and numerical values ​​set forth in these embodiments do not limit the scope of the present invention unless otherwise specifically stated.

[0034] The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses.

[0035] Technologies, methods, and equipment known to ordinary technicians in the relevant art may not be discussed in detail, but where appropriate, the technologies, methods, and equipment should be considered as part of the specification.

[0036] In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not limiting. Therefore, other examples of the exemplary embodiments may have different values.

[0037] It should be noted that like reference numerals and letters refer to similar items in the following figures, and therefore, once an item is defined in one figure, it need not be further discussed in subsequent figures.

[0038] The following describes a device 100 for measuring brain functional magnetic resonance imaging during resistance breathing according to an embodiment of the present invention in conjunction with the accompanying drawings.

[0039] like Figures 1 to 3 As shown, a device 100 for measuring brain functional magnetic resonance imaging during resistive breathing according to an embodiment of the present invention includes: a magnetic resonance device 10, a breathing mask 20, a pipeline 30 and a breathing training device 40.

[0040] Specifically, the magnetic resonance imager 10 is located in the magnetic resonance room 300, and is used to perform functional magnetic resonance imaging of the brain of the subject 400. The breathing mask 20 is installed on the magnetic resonance imager 10, and one end of the pipeline 30 is connected to the breathing mask 20. The breathing training device 40 is located outside the magnetic resonance room 300, and is connected to the other end of the pipeline 30 that passes through the wall of the magnetic resonance room 300. When the subject 400 breathes, the pressure in the pipeline 30 changes, and the breathing training device 40 senses the pressure change in the pipeline 30 to obtain breathing resistance data.

[0041] In other words, the measuring device 100 for brain functional magnetic resonance imaging during resistance breathing according to an embodiment of the present invention is mainly composed of a nuclear magnetic resonance instrument 10, a breathing mask 20, a pipeline 30 and a breathing training device 40. During the test, the subject can be located in the nuclear magnetic resonance room 300 and wear a breathing mask 20, which can be compatible with the nuclear magnetic resonance instrument 10. The breathing mask 20 is connected to one end of the pipeline 30, and the other end of the pipeline 30 is connected to the breathing training device 40 after passing through the wall. That is to say, in this embodiment, a breathing mask 20 and a pipeline 30 compatible with nuclear magnetic energy are used, and the subject wears the breathing mask 20 and is connected to the pipeline 30, which passes through the wall, so that the breathing training device 40 controls the resistance breathing.

[0042] Therefore, in this embodiment, by using the nuclear magnetic resonance device 10, the breathing mask 20, the pipeline 30 and the breathing training device 40 in coordination, accurate resistance breathing data can be guaranteed under the premise of nuclear magnetic resonance compatibility.

[0043] According to one embodiment of the present invention, a breathing valve is provided at the position of the communication pipeline 30 on the breathing mask 20. That is, in this embodiment, the breathing mask 20 is provided with a breathing valve, which can prevent the adverse reaction of repeated breathing pipeline air during the patient testing process.

[0044] In some specific embodiments of the present invention, a fixing belt is provided on the breathing mask 20 to fix the breathing mask 20 to the head of the tested person 400. That is, in this embodiment, the patient's head can be kept fixed to avoid the influence of head shaking.

[0045] The present invention also proposes a method for measuring brain functional magnetic resonance imaging during resistance breathing according to any of the above embodiments, comprising the following steps:

[0046] Fixing the breathing tube mask on the face of the test person 400;

[0047] Acquire brain functional magnetic resonance imaging of the subject 400 through a magnetic resonance imaging device 10;

[0048] The breathing training device 40 is used to test the pressure change in the pipeline 30 connected to the breathing tube mask to obtain the breathing resistance data.

[0049] That is to say, after the patient is ready, the MRI machine 10 and the breathing training machine 40 can be turned on. The MRI machine 10 obtains the brain functional MRI imaging of the test subject 400, and at the same time, the pressure in the pipeline 30 changes when the patient breathes, and the breathing training machine 40 senses the pressure change in the pipeline 30 and obtains the breathing resistance data.

[0050] The present invention also proposes a model construction method of a measuring device 100 based on brain functional magnetic resonance imaging during resistance breathing, comprising the following steps:

[0051] The characteristic data and brain functional magnetic resonance imaging data during the resistance breathing training are collected, wherein the characteristic data includes the resistance breathing training data. The brain functional magnetic resonance imaging test can be performed on the subject 400 while the resistance breathing training is being performed.

[0052] The characteristic data is matched with the brain functional nuclear magnetic imaging data to obtain a data sample. For example, when the patient breathes, the pressure in the pipeline 30 changes. After the breathing training device 40 senses the pressure change in the pipeline 30, the signal is transmitted to the data matching device. At the same time, the nuclear magnetic control console of the nuclear magnetic instrument 10 transmits the nuclear magnetic data to the data matching device through the nuclear magnetic signal transmission device. Finally, the data matching device matches and saves the nuclear magnetic data with the resistance breathing data. The brain functional nuclear magnetic imaging and respiratory resistance data of the testee 400 can be matched by a data processor. Specifically, the data processor is connected to the nuclear magnetic instrument 10 and the breathing training device 40 respectively, and the data processor matches the brain functional nuclear magnetic imaging and respiratory resistance data of the testee 400.

[0053] A model based on resistance breathing training and functional brain magnetic resonance imaging was constructed based on the data samples.

[0054] In this embodiment, a model can be constructed using the above method to achieve matching between resistance breathing training data and brain functional magnetic resonance imaging data during resistance breathing training, and changes in various brain functional areas of the test subject 400 under different degrees of resistance breathing can be obtained based on the above model.

[0055] According to one embodiment of the present invention, the characteristic data also includes the personal information of the testee 400, and the matching accuracy of the resistance breathing training data and the brain functional nuclear magnetic imaging data during resistance breathing training can be improved by refining the personal information. Optionally, the personal information of the testee 400 includes at least one of gender, date of birth, height, weight and disease information. In other words, the model can be refined according to the personal information of the testee 400 to improve the detection accuracy. The operator can set the required resistance breathing parameters and brain functional nuclear magnetic imaging parameters according to the research needs or the patient's condition.

[0056] In some specific embodiments of the present invention, the model building method of the measuring device 100 based on brain functional magnetic resonance imaging during resistance breathing further includes the following steps:

[0057] Collect resistance breathing parameters and brain functional magnetic resonance imaging parameters during resistance breathing training;

[0058] Detecting breathing training data based on resistance breathing parameters;

[0059] Detect brain functional magnetic resonance imaging data based on brain functional magnetic resonance imaging parameters.

[0060] The model building method based on resistance breathing training and functional brain MRI of this embodiment can pre-set resistance breathing parameters and functional brain MRI parameters in resistance breathing training, and then process the breathing training data and functional brain MRI data.

[0061] According to one embodiment of the present invention, the resistance breathing parameter includes at least one of the inhalation and / or exhalation pattern of the resistance breathing, the resistance value of the resistance breathing, and the number of breaths of the resistance breathing; the brain functional nuclear magnetic resonance imaging parameter includes at least one of the nuclear magnetic resonance structural image and the nuclear magnetic resonance BOLD sequence. In this embodiment, by adopting the above parameters, the accuracy of the data can be effectively guaranteed.

[0062] According to one embodiment of the present invention, the breathing training data includes at least one of the inhalation / expiration volume in resistance breathing training, the inhalation / expiration flow rate in resistance breathing training, etc.; the brain functional magnetic resonance imaging data includes at least one of the brain magnetic resonance structural image, the statistical parameters of the brain area activated by brain functional magnetic resonance imaging, etc., that is, the brain functional magnetic resonance data may include the brain magnetic resonance structural image and the statistical parameters of the activated brain area of ​​the test subject 400 under different resistance breathing states.

[0063] The present invention also provides a method for measuring brain functional magnetic resonance imaging during resistance breathing training, the method comprising the following steps:

[0064] Inputting the patient's data into the model of any of the above embodiments;

[0065] According to the matching data output by the model, the corresponding functional brain magnetic resonance imaging data is determined.

[0066] The method for measuring brain functional magnetic resonance imaging during resistance breathing training according to the embodiment of the present invention provides a convenient tool for researchers.

[0067] According to one embodiment of the present invention, the method for measuring brain functional magnetic resonance imaging during resistance breathing training further comprises the following steps:

[0068] The resistance breathing training data of the patient breathing under the first degree of resistance is input into the model, and the first brain functional magnetic resonance imaging data is output;

[0069] The resistance breathing training data of the patient breathing under the second degree of resistance is input into the model, and the second brain functional magnetic resonance imaging data is output;

[0070] Compare the change values ​​of the first functional MRI data and the second functional MRI data.

[0071] That is, in this embodiment, the changes in each brain functional area of ​​the test subject 400 under different degrees of resistance breathing can be obtained. The resistance breathing training data is matched with the synchronized brain functional MRI data through a program to obtain the functional parameters corresponding to each brain area of ​​the test subject 400 under different degrees of resistance breathing.

[0072] In addition, the present invention also provides a computer storage medium, including one or more computer instructions, which implement the model building method of any of the above embodiments when executed.

[0073] The present invention also provides an electronic device, such as a resistance breathing trainer, comprising: a processor 201 and a memory 202, wherein computer program instructions are stored in the memory 202, wherein when the computer program instructions are executed by the processor 201, the processor 201 executes the steps of the method in the above embodiment.

[0074] Furthermore, if Figure 2 As shown, the electronic device further includes a network interface 203 , an input device 204 , a hard disk 205 , and a display device 206 .

[0075] The above-mentioned interfaces and devices can be interconnected through a bus architecture. The bus architecture can include any number of interconnected buses and bridges. Specifically, one or more central processing units 201 (CPUs) represented by processor 201 and various circuits of one or more memories 202 represented by memory 202 are connected together. The bus architecture can also connect various other circuits such as peripheral devices, voltage regulators, and power management circuits together. It can be understood that the bus architecture is used to achieve connection and communication between these components. In addition to the data bus, the bus architecture also includes a power bus, a control bus, and a status signal bus, which are all well known in the art, so they will not be described in detail herein.

[0076] The network interface 203 can be connected to a network (such as the Internet, a local area network, etc.), obtain relevant data from the network, and save it in the hard disk 205.

[0077] The input device 204 can receive various instructions input by the operator and send them to the processor 201 for execution. The input device 204 can include a keyboard or a pointing device (for example, a mouse, a trackball, a touch pad or a touch screen, etc.).

[0078] The display device 206 can display the result obtained by the processor 201 executing the instruction.

[0079] The memory 202 is used to store programs and data necessary for the operation of the operating system 2021, as well as data such as intermediate results during the calculation process of the processor 201.

[0080] It is understood that the memory 202 in the embodiment of the present invention may be a volatile memory or a non-volatile memory, or may include both volatile and non-volatile memories. Among them, the non-volatile memory may be a read-only memory (ROM), a programmable read-only memory (PROM), an erasable programmable read-only memory (EPROM), an electrically erasable programmable read-only memory (EEPROM), or a flash memory. The volatile memory may be a random access memory (RAM), which is used as an external cache. The memory 202 of the apparatus and method described herein is intended to include, but is not limited to, these and any other suitable types of memory 202.

[0081] In some implementations, the memory 202 stores the following elements, executable modules or data structures, or a subset thereof, or an extended set thereof: an operating system 2021 and application programs 2022 .

[0082] The operating system 2021 includes various system programs, such as a framework layer, a core library layer, a driver layer, etc., which are used to implement various basic services and process hardware-based tasks. The application 2022 includes various application programs 2022, such as a browser, etc., which are used to implement various application services. The program for implementing the method of the embodiment of the present invention can be included in the application 2022.

[0083] The processor 201 executes the steps of the method according to the above embodiment when calling and executing the application 2022 and data stored in the memory 202, specifically, the program or instructions stored in the application 2022.

[0084] The method disclosed in the above embodiment of the present invention can be applied to the processor 201, or implemented by the processor 201. The processor 201 may be an integrated circuit chip with signal processing capabilities. In the implementation process, each step of the above method can be completed by the hardware integrated logic circuit in the processor 201 or the instruction in the form of software. The above processor 201 can be a general processor, a digital signal processor (DSP), an application specific integrated circuit (ASIC), a readily available programmable gate array (FPGA) or other programmable logic devices, discrete gates or transistor logic devices, discrete hardware components, and can implement or execute the methods, steps and logic block diagrams disclosed in the embodiments of the present invention. The general processor can be a microprocessor or the processor 201 can also be any conventional processor 201, etc. The steps of the method disclosed in conjunction with the embodiment of the present invention can be directly embodied as a hardware decoding processor to be executed, or can be executed by a combination of hardware and software modules in the decoding processor. The software module can be located in a mature storage medium in the field such as a random access memory, a flash memory, a read-only memory, a programmable read-only memory or an electrically erasable programmable memory, a register, etc. The storage medium is located in the memory 202, and the processor 201 reads the information in the memory 202 and completes the steps of the above method in combination with its hardware.

[0085] It is understood that the embodiments described herein can be implemented in hardware, software, firmware, middleware, microcode or a combination thereof. For hardware implementation, the processing unit can be implemented in one or more application specific integrated circuits (ASICs), digital signal processors (DSPs), digital signal processing devices (DSPDs), programmable logic devices (PLDs), field programmable gate arrays (FPGAs), general purpose processors, controllers, microcontrollers, microprocessors, other electronic units for performing the functions of the present invention or a combination thereof.

[0086] For software implementation, the technology herein can be implemented by modules (e.g., procedures, functions, etc.) that perform the functions herein. The software code can be stored in the memory 202 and executed by the processor 201. The memory 202 can be implemented in the processor 201 or outside the processor 201.

[0087] Specifically, the processor 201 is also used to read the computer program and execute the following steps: predict the pile charging method and output the answer to the question asked by the user.

[0088] The fourth aspect of the present invention also provides a computer-readable storage medium, which stores a computer program. When the computer program is executed by the processor 201, the processor 201 executes the steps of the method of the above embodiment.

[0089] In the several embodiments provided by the present invention, it should be understood that the disclosed methods and devices can be implemented in other ways. For example, the device embodiments described above are only schematic, for example, the division of units is only a logical function division, and there may be other division methods in actual implementation, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the mutual coupling or direct coupling or communication connection shown or discussed can be through some interfaces, indirect coupling or communication connection of devices or units, which can be electrical, mechanical or other forms.

[0090] In addition, each functional unit in each embodiment of the present invention may be integrated into one processing unit, or each unit may be physically included separately, or two or more units may be integrated into one unit. The above-mentioned integrated unit may be implemented in the form of hardware or in the form of hardware plus software functional units.

[0091] The above-mentioned integrated unit implemented in the form of a software functional unit can be stored in a computer-readable storage medium. The above-mentioned software functional unit is stored in a storage medium, including a number of instructions for a computer device (which can be a personal computer, a server, or a network device, etc.) to perform some steps of the sending and receiving methods of various embodiments of the present invention. The aforementioned storage medium includes: U disk, mobile hard disk, read-only memory (Read-Only Memory, referred to as ROM), random access memory (Random Access Memory, referred to as RAM), disk or optical disk and other media that can store program codes.

[0092] Although some specific embodiments of the present invention have been described in detail by way of example, it will be appreciated by those skilled in the art that the above examples are for illustration only and are not intended to limit the scope of the present invention. It will be appreciated by those skilled in the art that the above embodiments may be modified without departing from the scope and spirit of the present invention. The scope of the present invention is defined by the appended claims.

Claims

1. A device for measuring brain functional magnetic resonance imaging during resistance breathing, characterized in that: include: A nuclear magnetic resonance instrument, which is located in the nuclear magnetic resonance room and is used for performing nuclear magnetic resonance imaging of the brain function of the subject; A breathing mask, the breathing mask is installed on the nuclear magnetic resonance instrument; a pipeline, one end of which is connected to the breathing mask; A breathing trainer is located outside the MRI room and is connected to the other end of the pipeline passing through the wall of the MRI room. When the subject breathes, the pressure in the pipeline changes. The breathing trainer senses the pressure change in the pipeline and obtains breathing resistance data.

2. The measuring device for brain functional magnetic resonance imaging during resistance breathing according to claim 1, characterized in that: A breathing valve is arranged on the breathing mask at a position connected to the pipeline.

3. The measuring device for brain functional magnetic resonance imaging during resistance breathing according to claim 1, characterized in that: The breathing mask is provided with a fixing belt to fix the breathing mask to the head of the tested person.

4. A method for measuring the brain functional magnetic resonance imaging during resistance breathing according to any one of claims 1 to 3, characterized in that: The steps include: Fix the snorkel mask on the test subject’s face; Obtaining functional brain magnetic resonance imaging of the subject through magnetic resonance imaging; The breathing resistance data is obtained by testing the pressure change in the pipe connected to the breathing tube mask through the breathing training device.

5. A method for constructing a model of a device for measuring functional brain magnetic resonance imaging during resistance breathing, characterized in that: The steps include: Collecting characteristic data and brain functional magnetic resonance imaging data during resistance breathing training, wherein the characteristic data includes resistance breathing training data; Matching the characteristic data with the brain functional magnetic resonance imaging data to obtain a data sample; A model based on resistance breathing training and brain functional magnetic resonance imaging is constructed according to the data samples.

6. The method for constructing a model of a measuring device for brain functional magnetic resonance imaging during resistance breathing according to claim 5, characterized in that: The characteristic data also includes personal information of the test subject, and the personal information of the test subject includes at least one of gender, date of birth, height, weight and disease information.

7. The method for constructing a model of a measuring device for brain functional magnetic resonance imaging during resistance breathing according to claim 5, characterized in that: The following steps are also included: Collect resistance breathing parameters and brain functional magnetic resonance imaging parameters during resistance breathing training; detecting the breathing training data based on the resistance breathing parameter; The functional brain magnetic resonance imaging data is detected based on the functional brain magnetic resonance imaging parameters.

8. The method for constructing a model of a measuring device for brain functional magnetic resonance imaging during resistance breathing according to claim 7, characterized in that: The resistance breathing parameters include at least one of the inhalation and / or exhalation pattern of resistance breathing, the resistance value of resistance breathing, and the number of breaths of resistance breathing; the brain functional magnetic resonance imaging parameters include at least one of magnetic resonance structural images and magnetic resonance BOLD sequences.

9. A computer storage medium, characterized in that The method comprises one or more computer instructions, which implement the model building method according to any one of claims 5 to 8 when executed.

10. An electronic device comprising a memory and a processor, characterized in that: The memory is used to store one or more computer instructions; The processor is used to call and execute the one or more computer instructions, so as to implement the model building method according to any one of claims 5-8.