A pharmaceutical sterilization device and working method thereof

Abstract

The present invention discloses a pharmaceutical sterilization device and a working method thereof, comprising a housing and structures such as an air inlet pipe and an air outlet pipe arranged thereon. A sterilization chamber, an atomizer, etc. are arranged in the housing. The device sterilizes articles by circulating sterilizing steam, thereby reducing material and energy consumption. An annular guide plate is arranged in the sterilization chamber, which can guide the sterilizing steam to sterilize the bottom of the article. The present invention can realize zoned sterilization at different temperatures, and control valves and heaters according to demand. After steam sterilization is completed, air is introduced to discharge the sterilizing steam. The present invention reduces energy consumption, realizes zoned sterilization, and improves the flexibility and efficiency of sterilization.

Description

Technical Field

[0001] The invention relates to the technical field of pharmaceutical engineering, and in particular to a pharmaceutical sterilization device and a working method thereof. Background Art

[0002] In the pharmaceutical field, effective sterilization of drugs and related items is a key link to ensure drug quality and safety. Traditional pharmaceutical sterilization methods have some shortcomings.

[0003] On the one hand, existing sterilization devices are often not efficient enough in terms of energy consumption and material utilization. Many sterilization devices consume a lot of energy during operation, and the use of sterilization materials is not optimized, resulting in high costs.

[0004] On the other hand, in actual production, different medicines or items may need to be sterilized at different temperatures. However, existing sterilization devices are usually difficult to simultaneously meet the requirements of sterilizing multiple sterilization chambers at different temperatures, limiting the flexibility and efficiency of production. Summary of the invention

[0005] In view of the defects in the prior art, the present invention provides a pharmaceutical sterilization device and a working method thereof.

[0006] The present invention is achieved through the following technical solutions:

[0007] A pharmaceutical sterilization device comprises a shell, wherein an air inlet main pipe is arranged on the top of the shell, one end of the air inlet main pipe is an air inlet, an axial flow fan is arranged on the air inlet main pipe, a first heater, a first temperature sensor and a plurality of air inlet branches are arranged on the air inlet main pipe from the air outlet end of the axial flow fan to the other end of the air inlet main pipe in sequence, an atomization pipe, an air outlet main pipe and a first valve are arranged on the air inlet main pipe from the air inlet end of the axial flow fan to the air inlet in sequence, a second valve, a second temperature sensor, an exhaust pipe, an electrochemical sensor, a humidity sensor and a plurality of air outlet branches are arranged on the air outlet main pipe in sequence from close to the air inlet main pipe to far from the air inlet main pipe; a third valve and a second heater are arranged on the air inlet branch pipe, A third temperature sensor is provided at the air outlet end of the second heater; a plurality of disinfection chambers are provided in the shell, a nozzle is provided at the top of the disinfection chamber, the nozzle is connected to the air inlet branch pipe, the bottom of the disinfection chamber is connected to the air outlet branch pipe, an ultraviolet lamp is provided in the disinfection chamber, a disinfection rack is slidably installed in the disinfection chamber, an annular guide plate is provided on the disinfection rack, the center of the annular guide plate is an air vent, openings are provided on the annular guide plate along a circular array, the annular guide plate is an arc-shaped rotating body structure, that is, the shape of the annular guide plate is obtained by rotating along the rotating center axis with an arc as the rotating contour line; an atomizer is provided in the shell, and the atomizer is connected to the atomization pipe; a filter is connected to the exhaust pipe through a fourth valve.

[0008] Preferably, the first heater and the second heater are both composed of a heating tube and a ring heater. The ring heater is preferably a variable power heater. The ring heater is installed on the heating tube. Both ends of the heating tube of the first heater are installed on the air intake main pipe through flanges. Both ends of the heating tube of the second heater are installed on the air intake branch pipe through flanges. Insulating pads are provided between the flange on the air intake main pipe and the flange on the heating tube, and between the flange on the air intake branch pipe and the flange on the heating tube to reduce the impact of high temperature on the valve.

[0009] Preferably, the atomizer is provided with a metering pump for replenishing the sterilizing liquid in the atomizer, and the sterilizing liquid in the atomizer can be replenished by the metering pump.

[0010] Preferably, the first valve, the second valve, the third valve and the fourth valve are all solenoid valves.

[0011] Preferably, a guide groove is provided at the bottom of the disinfection chamber, and the air outlet branch pipe is connected to the bottom of the guide groove.

[0012] Preferably, a connecting rod is provided on the annular guide plate, and the annular guide plate is installed on the disinfection rack through the connecting rod.

[0013] Preferably, slideways are arranged in the disinfection chamber, and the disinfection racks are slidably placed on the slideways. The number and installation positions of the disinfection racks can be selected according to needs.

[0014] A working method of a pharmaceutical sterilization device is:

[0015] After placing the items to be sterilized on the disinfection rack, close the door of the disinfection chamber, control the UV lamp to turn on for UV disinfection, control the UV lamp to turn off after the UV disinfection is completed, and then perform steam sterilization;

[0016] If each sterilization chamber performs steam sterilization at the same temperature, the first valve and the fourth valve are controlled to be closed, and the second valve and the third valve at the sterilization chamber that needs to be started are opened; the axial flow fan, the atomizer and the first heater are controlled to be started, and the atomizer inputs the atomized sterilizing liquid into the air inlet main pipe. Under the action of the axial flow fan and the first heater, the sterilizing steam of the required temperature is continuously circulated along the air inlet main pipe, the air inlet branch pipe, the sterilization chamber, the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe. The temperature of the first heater is controlled based on the monitoring of the circulating sterilizing steam temperature by the first temperature sensor and the second temperature sensor;

[0017] If each sterilization chamber performs steam sterilization at different temperatures, the first valve, the second valve, the fourth valve and the third valve at the sterilization chamber that needs to be started are controlled to be opened; the temperature of the first heater is controlled based on the temperature of the sterilization chamber with the lowest required temperature as the basic temperature, so that the temperature value detected by the first temperature sensor is the same as the basic temperature, and the remaining sterilization chambers control the temperature of the corresponding second heaters according to the required temperature and the monitoring of the sterilization steam temperature by the third temperature sensor; a part of the sterilization steam is continuously circulated along the air inlet main pipe, the air inlet branch pipe, the sterilization chamber, the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe, and the other part of the sterilization steam is discharged from the exhaust pipe, and new air enters the air inlet to cool the circulating sterilization steam to prevent the circulating sterilization steam temperature from being higher than the basic temperature; if the temperature value detected by the first temperature sensor is higher than the basic temperature, the opening of the second valve is controlled to be reduced until the temperature value detected by the first temperature sensor is the same as the basic temperature;

[0018] Preferably, after steam sterilization is completed, the first valve and the fourth valve are controlled to be opened, the second valve is closed, and the third valves remain unchanged. The atomizer, the first heater and the second heaters are controlled to be closed. Under the action of the axial flow fan, air is continuously introduced to allow the sterilization steam to enter the filter through the exhaust pipe for filtration and then be discharged. When the humidity value detected by the humidity sensor is lower than the preset value, the removal of the sterilization steam is completed.

[0019] The beneficial effects of the present invention are as follows: the present invention sterilizes articles in a sterilization bin by circulating sterilizing steam, thereby reducing the consumption of materials and energy; the present invention can guide the circulating sterilizing steam by adding an annular guide plate to sterilize the bottom of the articles; the present invention can simultaneously perform zoned sterilization at different temperatures on each sterilization bin; the present invention can quickly obtain sterilizing steam by atomizing the sterilizing liquid and then heating it, thereby improving the sterilization efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following is a brief introduction to the drawings required for the specific embodiments or the description of the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn according to the actual scale.

[0021] Figure 1 It is an axonometric drawing of the present invention.

[0022] Figure 2 It is a top view of the present invention.

[0023] Figure 3 for Figure 2 A-section view.

[0024] Figure 4 for Figure 3Enlarged view of point A.

[0025] Figure 5 It is an axonometric view of the disinfection chamber of the present invention.

[0026] Figure 6 It is an axonometric view of the disinfection rack of the present invention.

[0027] Figure 7 It is an axonometric view of the annular guide plate of the present invention.

[0028] Figure 8 It is a cross-sectional view of the annular flow guide plate of the present invention.

[0029] In the attached drawings, 1, housing; 2, air inlet pipe; 3, axial flow fan; 4, first heater; 5, first temperature sensor; 6, third valve; 7, second heater; 8, atomizer pipe; 9, atomizer; 10, metering pump; 11, air outlet pipe; 12, first valve; 13, second valve; 14, second temperature sensor; 15, fourth valve; 16, filter; 17, electrochemical sensor; 18, humidity sensor; 19, heating pipe; 20, annular heater; 21, insulation pad; 22, third temperature sensor; 23, disinfection chamber; 24, nozzle; 25, disinfection rack; 26, annular guide plate; 27, ultraviolet lamp; 28, guide groove; 29, vent; 30, opening; 31, connecting rod; 32, operating table. DETAILED DESCRIPTION

[0030] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0031] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be an intermediate element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element at the same time.

[0032] For ease of description, spatial relative terms such as "upper," "lower," "left," and "right" may be used herein to describe the relationship of one element or feature shown in a figure relative to another element or feature. It should be understood that the spatial terms are intended to include different orientations of the device in use or operation in addition to the orientation shown in the figures. For example, if the device in the figure is inverted, elements described as being "below" other elements or features will be positioned "above" the other elements or features. Thus, the exemplary term "below" may include both upper and lower orientations.

[0033] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0034] The present invention will be described in detail below in conjunction with the accompanying drawings:

[0035] The pharmaceutical sterilization device in this embodiment mainly includes a solid shell 1. An air intake main pipe 2 is arranged on the top of the shell 1, one end of which is an air inlet, and an axial flow fan 3 is installed on the air intake main pipe 2 to promote air flow. Starting from the air outlet end of the axial flow fan 3, the first heater 4, the first temperature sensor 5 and a plurality of air intake branches are installed on the air intake main pipe 2 in sequence. From the air inlet end of the axial flow fan 3 to the air inlet direction, the air intake main pipe 2 is sequentially provided with an atomization pipe 8, an air outlet main pipe 11 and a first valve 12.

[0036] A second valve 13 is arranged on the outlet pipe 11 near the inlet pipe 2, followed by a second temperature sensor 14, an exhaust pipe, an electrochemical sensor 17, a humidity sensor 18 and a plurality of outlet branches. The exhaust pipe is connected to a filter 16 through a fourth valve 15.

[0037] The air intake branch pipe is provided with a third valve 6 and a second heater 7 , and an air outlet end of the second heater 7 is provided with a third temperature sensor 22 .

[0038] A plurality of disinfection chambers 23 are arranged in the housing 1, and a nozzle 24 is installed at the top of the disinfection chamber 23, which is connected to the air inlet branch pipe. A guide groove 28 is arranged at the bottom of the disinfection chamber 23, which is connected to the air outlet branch pipe. An ultraviolet lamp 27 is also arranged in the disinfection chamber 23 for preliminary disinfection. A disinfection rack 25 is slidably installed in the disinfection chamber 23, and an annular guide plate 26 is installed on the disinfection rack 25 through a connecting rod 31. The annular guide plate 26 is an arc-shaped rotating body structure, with a vent 29 at the center, and an opening 30 is arranged in a circumferential array on the annular guide plate 26. Slideways are arranged in the disinfection chamber 23, and the disinfection rack 25 can slide on the slideways, which is convenient for adjusting the quantity and position.

[0039] The first heater 4 and the second heater 7 are both composed of a heating tube 19 and a ring heater 20. The ring heater 20 is a variable power heater, which is respectively installed on the air intake main pipe 2 and the air intake branch pipe, and a heat insulation pad 21 is provided at the connection. The atomizer 9 is arranged in the housing 1 and connected to the atomizing tube 8. The atomizer 9 is provided with a metering pump 10 to replenish the sterilizing liquid. The first valve 12, the second valve 13, the third valve 6 and the fourth valve 15 are all electromagnetic valves.

[0040] UV disinfection stage:

[0041] After the items to be sterilized are placed on the disinfection rack 25 , the door of the disinfection chamber 23 is closed.

[0042] The ultraviolet lamp 27 that needs to be started is controlled to be turned on for ultraviolet disinfection, and some microorganisms are killed by the radiation effect of ultraviolet rays. After the ultraviolet disinfection is completed, the ultraviolet lamp 27 is controlled to be turned off.

[0043] Steam sterilization stage:

[0044] Steam sterilization at the same temperature:

[0045] The first valve 12 and the fourth valve 15 are controlled to be closed, and the second valve 13 and the third valve 6 at the disinfection chamber 23 that needs to be started are opened.

[0046] The axial flow fan 3, the atomizer 9 and the first heater 4 are controlled to start. The atomizer 9 inputs the atomized sterilizing liquid into the air inlet main pipe. Under the action of the axial flow fan 3 and the first heater 4, the hot air is mixed with the atomized sterilizing liquid to form sterilizing steam of the required temperature, and circulates continuously along the air inlet main pipe, the air inlet branch pipe, the disinfection chamber 23, the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe.

[0047] Based on the monitoring of the circulating steam temperature by the first temperature sensor 5 and the second temperature sensor 14, the temperature of the first heater 4 is controlled, the first heater 4 is initially regulated according to the temperature value detected by the second temperature sensor 14, and the first heater 4 is secondarily regulated according to the temperature value detected by the first temperature sensor 5 to ensure that the temperature is stable at the set value.

[0048] During the sterilization process, the fourth valve 15 can be selectively opened to release pressure.

[0049] Steam sterilization at different temperatures:

[0050] The first valve 12, the second valve 13, the fourth valve 15 and the third valve 6 at the sterilization chamber 23 that needs to be started are controlled to be opened.

[0051] The temperature of the sterilization chamber 23 with the lowest required temperature is used as the base temperature to control the temperature of the first heater 4, so that the temperature value detected by the first temperature sensor 5 is the same as the base temperature. The remaining sterilization chambers 23 control the temperature of the corresponding second heater 7 according to the required temperature and the monitoring of the sterilization steam temperature by the third temperature sensor 22, so as to meet the sterilization temperature required by each sterilization chamber 23.

[0052] When the equipment is running, a part of the sterilizing steam circulates continuously along the air inlet main pipe, the air inlet branch pipe, the disinfection chamber 23, the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe, and the other part of the sterilizing steam is discharged from the exhaust pipe, that is, the exhaust pipe can play a pressure relief role at this time. During the circulation of the sterilizing steam, new air enters the air inlet to cool the circulating sterilizing steam to prevent the circulating sterilizing steam temperature from being higher than the base temperature. If the temperature value detected by the first temperature sensor 5 is higher than the base temperature, the opening of the second valve 13 is controlled to be reduced until the temperature value detected by the first temperature sensor 5 is the same as the base temperature.

[0053] As a preferred solution, a fourth temperature sensor is provided on the air inlet main pipe 2 between the air inlet end of the axial flow fan 3 and the air outlet main pipe 11. If the temperature value detected by the fourth temperature sensor is higher than the base temperature, the opening of the second valve 13 is controlled to be reduced until it is closed, so that the temperature value detected by the first temperature sensor 5 is the same as the base temperature.

[0054] Sterilization Steam Removal Phase:

[0055] After steam sterilization is completed, the first valve 12 and the fourth valve 15 are controlled to be opened, the second valve 13 is closed, and the third valves 6 remain unchanged.

[0056] The atomizer 9, the first heater 4 and each of the second heaters 7 are controlled to be turned off.

[0057] Air is continuously introduced under the action of the axial flow fan 3, so that the sterilizing steam enters the filter 16 through the exhaust pipe for filtration and then is discharged. When the humidity value detected by the humidity sensor 18 is lower than the preset value, the sterilizing steam removal is completed.

[0058] The present invention adopts a controller to control each component, and an operating table 32 connected to the controller is arranged on the shell 1 for operation. The controller takes PLC as the core, and is respectively connected with each valve, each heater, each temperature sensor, humidity sensor 18, electrochemical sensor 17, ultraviolet lamp 27, atomizer 9 and metering pump 10, wherein each valve adopts a solenoid valve; each heater adopts a variable power ring heater 20, and the ring heater 20 is controlled according to the data fed back by the temperature sensor to obtain sterilizing steam of the required temperature; the metering pump 10 is controlled by the controller to operate to replenish the sterilizing liquid in the atomizer 9.

[0059] When the sterilizing liquid is a solution containing chemical substances, the electrochemical sensor 17 can detect the concentration of chemical substances in the sterilizing steam. For example, when hydrogen peroxide solution is used as the sterilizing liquid, the electrochemical sensor 17 can detect the concentration of hydrogen peroxide in the sterilizing steam. In actual operation, the atomizer 9 can also be controlled according to the electrochemical sensor 17. When the concentration value detected by the electrochemical sensor 17 is higher than the preset value, the atomizer 9 is controlled to stop working. When the concentration value detected by the electrochemical sensor 17 is lower than the preset value, the atomizer 9 is controlled to start. When hydrogen peroxide solution is used as the sterilizing liquid, the temperature of the sterilizing steam should be controlled at 40-60 degrees Celsius. The filter 16 uses a filtrate containing activated carbon as an adsorbent, and a filtrate containing metal oxides such as manganese dioxide can also be used as an adsorbent.

[0060] When the sterilizing liquid does not contain any chemical substance and only pure water is used, the temperature of the sterilizing steam can be controlled at 60-120 degrees Celsius, or a higher temperature can be used. Since the sterilizing liquid does not contain any chemical substance, the electrochemical sensor 17 is not required, and the controller can be used to control the electrochemical sensor 17 not to collect data, and the filter 16 can use a filter 16 containing activated carbon.

[0061] When a sterilizing liquid with other components is used, the filtered material in the filter 16 can be adjusted according to the components of the sterilizing liquid.

[0062] In the present invention, an annular guide plate 26 is arranged on the disinfection rack 25 for diversion. The arc structure of the annular guide plate 26 can divert a portion of the sterilization steam, thereby sterilizing the bottom of the sterilized items. The center position of the annular guide plate 26 is a vent 29, and the annular guide plate 26 is provided with openings 30 along the circumference array. The vent 29 and the openings 30 can allow the sterilization steam to pass through, so as to sterilize the items to be sterilized on the lower disinfection rack 25.

[0063] Embodiment 1:

[0064] In this embodiment, the number of the sterilization chambers 23 is set to two, and both sterilization chambers 23 are in operation and perform steam sterilization at different temperatures. In this embodiment, pure water is used as the sterilization liquid.

[0065] The sterilization steam temperatures required for the two sterilization chambers 23 are set to 100 degrees Celsius and 120 degrees Celsius respectively through the operating table 32, and the first valve 12, the second valve 13, the fourth valve 15 and the two third valves 6 are controlled to be opened, and the atomizer 9, the first heater 4 and one of the second heaters 7 are controlled to start, and the first heater 4 heats the air in the pipe to 100 degrees Celsius through the cooperation of the first temperature sensor 5 and the first heater 4, forming 100 degrees Celsius sterilization steam, and the 100 degrees Celsius sterilization steam is heated to 120 degrees Celsius through the cooperation of the started second heater 7 and the corresponding third temperature sensor 22, thereby completing steam sterilization at different temperatures; since part of the sterilization steam enters the air intake main pipe 2 for circulation, the power of the first heater 4 will become smaller and smaller. In the actual operation process, the temperature value detected at the first temperature sensor 5 does not exceed 100 degrees Celsius, so there is no need to adjust the second valve 13.

[0066] Through actual measurement using a fourth temperature sensor added to the air inlet end of the axial flow fan 3, the temperature of the sterilizing steam did not exceed 100 degrees Celsius, thus verifying that there was no need to adjust the second valve 13 at this time.

[0067] Embodiment 2:

[0068] In this embodiment, the number of the disinfection chambers 23 is set to two, and both disinfection chambers 23 are in operation and perform steam sterilization at the same temperature. In this embodiment, hydrogen peroxide solution is used as the sterilization liquid.

[0069] The sterilization steam temperature required for the two disinfection chambers 23 is set to 50 degrees Celsius through the operating console 32, the first valve 12 and the fourth valve 15 are controlled to be closed, the second valve 13 and the two third valves 6 are controlled to be opened, the atomizer 9 and the first heater 4 are controlled to start, and the first temperature sensor 5 and the first heater 4 cooperate to make the first heater 4 heat the temperature inside the tube to 50 degrees Celsius to form sterilization steam at 50 degrees Celsius. Since the sterilization steam is internally circulated, the power of the first heater 4 needs to be gradually reduced.

[0070] During the sterilization steam circulation process and the sterilization steam removal stage, the electrochemical sensor 17 can be operated to detect the concentration of hydrogen peroxide in the sterilization steam. In the sterilization steam circulation stage, when the concentration value detected by the electrochemical sensor 17 is higher than the preset value, the nebulizer 9 is controlled to stop working, and when the concentration value detected by the electrochemical sensor 17 is lower than the preset value, the nebulizer 9 is controlled to start. In the sterilization steam removal stage, the electrochemical sensor 17 and the humidity sensor 18 can be used to better determine whether the sterilization steam is removed. When the values ​​detected by the two sensors are lower than the preset values, the sterilization steam removal is completed.

[0071] Embodiment 3:

[0072] In this embodiment, the number of the sterilization chambers 23 is set to four, and all four sterilization chambers 23 are in operation and perform steam sterilization at different temperatures. In this embodiment, pure water is used as the sterilization liquid.

[0073] The sterilization steam temperatures required for the four sterilization chambers 23 are set to 50 degrees Celsius, 100 degrees Celsius, 110 degrees Celsius and 120 degrees Celsius respectively through the operating table 32, and the first valve 12, the second valve 13, the fourth valve 15 and the four third valves 6 are controlled to be opened, and the atomizer 9, the first heater 4 and three of the second heaters 7 are controlled to be started. Through the cooperation of the first temperature sensor 5 and the first heater 4, the first heater 4 heats the gas in the tube to 50 degrees Celsius to form 50 degrees Celsius sterilization steam, and each of the started second heaters 7 and the corresponding third temperature sensors are connected. 22 cooperates to heat the sterilization steam at 50 degrees Celsius to form sterilization steam at 100 degrees Celsius, 110 degrees Celsius and 120 degrees Celsius respectively to meet the different sterilization requirements of each disinfection chamber 23; during operation, when the second valve 13 is fully open, the temperature value detected by the first temperature sensor 5 is greater than 50 degrees Celsius. At this time, it is necessary to control the opening of the second valve 13 to be reduced, thereby reducing the high-temperature sterilization steam entering the circulation and increasing the low-temperature air entering from the air inlet, so that the temperature of the sterilization steam at the axial flow fan 3 can be reduced to 50 degrees Celsius or below.

[0074] The opening degree of the second valve 13 can be regulated by selecting 10% as a step.

[0075] Embodiment 4:

[0076] In this embodiment, the number of sterilization chambers 23 is set to four, of which three sterilization chambers 23 are subjected to steam sterilization. Then, the third solenoid valves at the three sterilization chambers 23 that need to be operated are controlled to be opened, and the third solenoid valves at the sterilization chambers 23 that do not need to be operated are closed.

[0077] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and specification of the present invention.

Claims

1. A pharmaceutical sterilization device, comprising a housing (1), characterized in that: An air intake pipe (2) is arranged at the top of the housing (1), one end of the air intake pipe (2) is an air inlet, an axial flow fan (3) is arranged on the air intake pipe (2), a first heater (4), a first temperature sensor (5) and a plurality of air intake branch pipes are arranged in sequence on the air intake pipe (2) from the air outlet end of the axial flow fan (3) to the other end of the air intake pipe (2), an atomization pipe (8), an air outlet pipe (11) and a first valve (12) are arranged in sequence on the air intake pipe (2) from the air inlet end of the axial flow fan (3) to the air inlet, a second valve (13), a second temperature sensor (14), an exhaust pipe, an electrochemical sensor (17), a humidity sensor (18) and a plurality of air outlet branch pipes are arranged in sequence on the air outlet pipe (11) from close to the air intake pipe (2) to far from the air intake pipe (2); a third valve (6) and a second heater (7) are arranged on the air intake branch pipe, and a third temperature sensor (22) is arranged at the air outlet end of the second heater (7). The housing (1) is provided with a plurality of disinfection chambers (23), a nozzle (24) is provided at the top of the disinfection chamber (23), the nozzle (24) is connected to the air inlet branch pipe, the bottom of the disinfection chamber (23) is connected to the air outlet branch pipe, an ultraviolet lamp (27) is provided in the disinfection chamber (23), a disinfection rack (25) is slidably installed in the disinfection chamber (23), an annular guide plate (26) is provided on the disinfection rack (25), and a connecting rod (31) is provided on the annular guide plate (26) The annular guide plate (26) is mounted on the disinfection rack (25) via a connecting rod (31); the center of the annular guide plate (26) is a vent (29); openings (30) are arranged in a circular array on the annular guide plate (26); the annular guide plate (26) is an arc-shaped rotating body structure; an atomizer (9) is arranged in the housing (1); the atomizer (9) is connected to the atomization pipe (8); and a filter (16) is connected to the exhaust pipe via a fourth valve (15).

2. The pharmaceutical sterilization device according to claim 1, characterized in that: The first heater (4) and the second heater (7) are both composed of a heating tube (19) and a ring heater (20). The ring heater (20) is mounted on the heating tube (19). Both ends of the heating tube (19) of the first heater (4) are mounted on the air intake main pipe (2) via flanges. Both ends of the heating tube (19) of the second heater (7) are mounted on the air intake branch pipe via flanges. A heat insulating pad (21) is provided between the flange on the air intake main pipe (2) and the flange on the heating tube (19), and between the flange on the air intake branch pipe and the flange on the heating tube (19).

3. The pharmaceutical sterilization device according to claim 1, characterized in that: The atomizer (9) is provided with a metering pump (10) for replenishing the sterilizing liquid in the atomizer (9).

4. The pharmaceutical sterilization device according to claim 1, characterized in that: The first valve (12), the second valve (13), the third valve (6) and the fourth valve (15) are all solenoid valves.

5. The pharmaceutical sterilization device according to claim 1, characterized in that: A guide groove (28) is provided at the bottom of the disinfection chamber (23), and an air outlet branch pipe is connected to the bottom of the guide groove (28).

6. The pharmaceutical sterilization device according to claim 1, characterized in that: Slideways are arranged in the disinfection chamber (23), and the disinfection rack (25) is slidably placed on the slideways.

7. The working method of the pharmaceutical sterilization device according to claim 1, characterized in that: After placing the items to be sterilized on the sterilization rack (25), closing the door of the sterilization chamber (23), controlling the ultraviolet lamp (27) to turn on for ultraviolet sterilization, and controlling the ultraviolet lamp (27) to turn off after the ultraviolet sterilization is completed, and then performing steam sterilization; If each sterilization chamber (23) is subjected to steam sterilization at the same temperature, the first valve (12) and the fourth valve (15) are controlled to be closed, and the second valve (13) and the third valve (6) at the sterilization chamber (23) to be started are opened; the axial flow fan (3), the atomizer (9) and the first heater (4) are controlled to be started, and the atomizer (9) inputs the atomized sterilizing liquid into the air inlet main pipe. Under the action of the axial flow fan (3) and the first heater (4), the sterilizing steam at the required temperature is continuously circulated along the air inlet main pipe, the air inlet branch pipe, the sterilization chamber (23), the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe. Based on the monitoring of the circulating sterilizing steam temperature by the first temperature sensor (5) and the second temperature sensor (14), the temperature of the first heater (4) is controlled; If each sterilization chamber (23) performs steam sterilization at a different temperature, the first valve (12), the second valve (13), the fourth valve (15) and the third valve (6) at the sterilization chamber (23) to be started are controlled to be opened; the temperature of the first heater (4) is controlled based on the temperature of the sterilization chamber (23) with the lowest required temperature as the base temperature, so that the temperature value detected by the first temperature sensor (5) is the same as the base temperature; the remaining sterilization chambers (23) are controlled based on the required temperature and the monitoring of the sterilization steam temperature by the third temperature sensor (22). The second heater (7) performs temperature control; a portion of the sterilizing steam circulates continuously along the air inlet main pipe, the air inlet branch pipe, the sterilization chamber (23), the air outlet branch pipe, the air outlet main pipe and the air inlet main pipe, and another portion of the sterilizing steam is discharged from the exhaust pipe. New air enters the air inlet to cool the circulating sterilizing steam, thereby preventing the circulating sterilizing steam from having a temperature higher than the base temperature; if the temperature value detected by the first temperature sensor (5) is higher than the base temperature, the opening of the second valve (13) is controlled to decrease until the temperature value detected by the first temperature sensor (5) is the same as the base temperature.

8. The working method of the pharmaceutical sterilization device according to claim 7, characterized in that: After steam sterilization is completed, the first valve (12) and the fourth valve (15) are controlled to be opened, the second valve (13) is closed, and the third valves (6) remain unchanged. The atomizer (9), the first heater (4) and the second heaters (7) are controlled to be closed. Under the action of the axial flow fan (3), air is continuously introduced to allow the sterilization steam to enter the filter (16) through the exhaust pipe for filtration and then be discharged. When the humidity value detected by the humidity sensor (18) is lower than the preset value, the removal of the sterilization steam is completed.

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