Biochemical analysis equipment and photometric device thereof

By using a combination of diffraction elements and extinction components in biochemical analysis equipment, the problem of stray light influence in spectroscopic detection after grating is solved, and fast and accurate multi-channel detection is achieved.

CN119310044APending Publication Date: 2025-01-14AUTOBIO LABTEC INSTR CO LTD
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Patent Information

Application Number
CN202411564825.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-05
Publication Date
2025-01-14

AI Technical Summary

Technical Problem

When using the spectroscopic detection method after grating, existing biochemical analysis equipment needs to eliminate stray light processing to reduce the impact of stray light on analysis and detection, affecting the detection speed and accuracy.

Method used

Design a light metering device, including a diffraction element, a detection module and an extinction component. The light beam to be measured is diffraction through the diffraction element, and the light to be measured is selected to be incident to the detection module. The light non-selected is incident to the extinction component for extinction processing, reducing stray light effects.

Benefits of technology

Effectively reduce the impact of stray light on analysis and detection, improve detection speed and accuracy, especially when multi-channel simultaneous measurement and high-absorbance solution detection.

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Abstract

The invention discloses biochemical analysis equipment and a photometric device thereof, the photometric device comprises a diffraction element, a detection module and an extinction component, when a to-be-detected light beam enters the diffraction element, the to-be-detected light beam diffracts, so that the selected-order light in the diffracted light enters the detection module, and the selected-order light in the diffracted light enters the extinction component; the detection module is arranged on the light emitting side of the diffraction element and corresponds to the emitting angle of the selected-order light in the diffraction light, the detection module comprises at least one detection element which is arranged in sequence, and the at least one detection element is used for detecting channel light with different wavelengths in the selected-order light. The extinction component is arranged on the light emitting side of the diffraction element and corresponds to the emitting angle of the non-selection-order light in the diffraction light, so that the non-selection-order light enters the extinction component to be subjected to extinction processing. The stray light can be reduced, and the influence of the stray light on analysis and detection is reduced.
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Description

Technical Field

[0001] The invention relates to the field of optical systems, and in particular to a biochemical analysis device and a light measuring device thereof. Background Art

[0002] Currently, some biochemical analysis equipment on the market uses a pre-spectral detection method using a filter wheel, such as semi-automatic and low-speed biochemical analysis equipment. This spectroscopic detection method requires switching filters to achieve detection of different wavelength channels, so its detection speed is limited.

[0003] Other biochemical analysis equipment uses a grating post-spectral detection method, which can simultaneously separate light beams of different wavelengths and emit each light beam to a different position. Detection devices can be set at different positions to achieve real-time detection of different wavelength channels, which can significantly improve the detection speed. For example, this method is used in high-speed fully automatic biochemical analysis equipment. However, the grating post-spectral detection method requires stray light elimination processing to minimize the impact of stray light on analysis and detection. Summary of the invention

[0004] The object of the present invention is to provide a biochemical analysis device and a light measuring device thereof, which can reduce stray light and reduce the influence of stray light on analysis and detection.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A light measuring device, comprising:

[0007] A diffraction element, used for diffracting the light beam to be measured when the light beam to be measured is incident on the diffraction element, so that the selected order light in the diffracted light is incident on the detection module;

[0008] The detection module is arranged at the light-emitting side of the diffraction element and corresponds to the emission angle of the selected order light in the diffracted light, and includes at least one detection element arranged in sequence, and the at least one detection element is respectively used to detect different wavelength channel lights in the selected order light;

[0009] The extinction component is arranged on the light-emitting side of the diffraction element and corresponds to the emission angle of the non-selected order light in the diffracted light, and is used to make the non-selected order light incident on the extinction component to perform extinction processing on the non-selected order light.

[0010] Optionally, a plurality of the extinction components are included, the diffracted light includes multiple levels of non-selected order light, the multiple levels of non-selected order light have different emission angles, and the plurality of extinction components are respectively arranged corresponding to the emission angles of the non-selected order light of different orders.

[0011] Optionally, the extinction component includes an extinction cavity, so that the non-selected order light is incident into and trapped in the extinction cavity.

[0012] Optionally, the inner surface of the extinction cavity is absorptive to the non-selected order light.

[0013] Optionally, an opening is provided at one end of the extinction cavity, and the extinction cavity extends in the depth direction, so that the non-selected order light is incident on the opening and enters the extinction cavity, and after entering the extinction cavity, it is reflected multiple times by the inner surface of the extinction cavity and is trapped in the extinction cavity.

[0014] Optionally, the at least one detection element is respectively arranged corresponding to the emission angles of different wavelength channel lights in the selected order light;

[0015] The detection module also includes:

[0016] At least one first slit, the first slit of the at least one first slit is arranged in a one-to-one correspondence with the detection element of the at least one detection element, and the first slit is arranged on the light incident side of the corresponding detection element, so as to allow the corresponding wavelength channel light in the selected order light to pass through the first slit and be incident on the corresponding detection element.

[0017] Optionally, the detection module further includes:

[0018] At least one second slit, the second slit of the at least one second slit is arranged in a one-to-one correspondence with the detection element of the at least one detection element, the second slit is arranged on the side of the corresponding first slit close to the detection element, and is used to allow light from the corresponding first slit to pass through the second slit and be incident on the corresponding detection element, and block light from other first slits from being incident on the corresponding detection element, and the other first slits refer to other first slits except the first slit corresponding to the second slit.

[0019] Optionally, the sidewalls of the second slits are used to block light from other first slits from being incident on the corresponding detection element.

[0020] Optionally, the sidewall of the second slit is light absorptive.

[0021] A biochemical analysis device, comprising:

[0022] A light source device, used for emitting light, so that the light is irradiated to the object to be measured, so that the object to be measured generates a light beam to be measured;

[0023] The light measuring device described in any one of the above items is arranged on one side of the object to be measured, so that the light beam to be measured is incident on the diffraction element of the light measuring device.

[0024] It can be known from the above technical scheme that a photometric device provided by the present invention includes a diffraction element, a detection module and an extinction component. When the light beam to be measured is incident on the diffraction element, the light beam to be measured is diffracted, so that the selected order light in the diffracted light is incident on the detection module. The detection module is arranged on the light-exiting side of the diffraction element and corresponds to the exit angle of the selected order light in the diffracted light. It includes at least one detection element arranged in sequence, and the at least one detection element is used to detect different wavelength channel lights in the selected order light. The extinction component is arranged on the light-exiting side of the diffraction element and corresponds to the exit angle of the non-selected order light in the diffracted light, so that the non-selected order light is incident on the extinction component to extinct the non-selected order light. The photometric device of the present invention is provided with an extinction component on the light-exiting side of the diffraction element, and uses the extinction component to extinct the generated non-selected order light, thereby reducing the influence of these stray lights on analysis and detection.

[0025] The biochemical analysis equipment provided by the present invention can achieve the above beneficial effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0027] FIG1 is a schematic diagram of a biochemical analysis device provided by an embodiment of the present invention;

[0028] FIG2 is a schematic diagram of the structure of a detection module of a light measuring device provided by an embodiment of the present invention;

[0029] FIG. 3 is an exploded schematic diagram of the detection module shown in FIG. 2 .

[0030] The reference numerals in the drawings of the specification include:

[0031] 1-light source device, 2-first lens group, 3-second lens group, 4-diffraction element, 5-first extinction cavity, 6-second extinction cavity, 7-detection module, 71-filter element array, 72-first slit array, 73-second slit array, 74-detection element array, 75-detection element, 76-second slit, 77-first slit, 78-filter element. DETAILED DESCRIPTION

[0032] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0033] This embodiment provides a light measuring device, including:

[0034] A diffraction element, used for diffracting the light beam to be measured when the light beam to be measured is incident on the diffraction element, so that the selected order light in the diffracted light is incident on the detection module;

[0035] The detection module is arranged at the light-emitting side of the diffraction element and corresponds to the emission angle of the selected order light in the diffracted light, and includes at least one detection element arranged in sequence, and the at least one detection element is respectively used to detect different wavelength channel lights in the selected order light;

[0036] The extinction component is arranged on the light-emitting side of the diffraction element and corresponds to the emission angle of the non-selected order light in the diffracted light, and is used to make the non-selected order light incident on the extinction component to perform extinction processing on the non-selected order light.

[0037] When the measured light beam is incident on the diffraction element, the measured light beam is diffracted, and the generated diffracted light includes multiple order diffracted light. Selected order light refers to the corresponding order diffracted light selected from the diffracted light and to be detected. Non-selected order light refers to other order diffracted light in the diffracted light except the selected order light. Any order diffracted light includes different wavelength channel lights belonging to the diffraction order.

[0038] The detection module corresponds to the emission angle of the selected order light in the diffracted light, so that the selected order light in the diffracted light is incident on the detection module. The at least one detection element of the detection module is used to detect different wavelength channel lights in the selected order light respectively to realize the detection of the light beam to be measured.

[0039] The extinction component corresponds to the exit angle of the non-selected order light in the diffracted light, so that the non-selected order light in the diffracted light is incident on the extinction component, and the non-selected order light is extincted by the extinction component. Extinction processing refers to weakening or even eliminating the energy of light. Therefore, the light measuring device of this embodiment is provided with an extinction component on the light exit side of the diffraction element, and the extinction component is used to extinct the generated non-selected order light, thereby reducing the influence of these stray lights on analysis and detection.

[0040] In this embodiment, the structure of the diffraction element is not limited, as long as the measured light beam can be diffracted to generate a spectrum when the measured light beam is incident on the diffraction element. In some embodiments, the diffraction element may include a reflective diffraction element. The reflective diffraction element reflects the diffracted light generated by the measured light beam, which can not only change the direction of the light beam, but also greatly reduce the overall size of the light measuring device, which is convenient for the light measuring device to be integrated into the instrument. The diffraction element can adopt a concave reflective diffraction element, which has the function of converging the light beam on the basis of the reflective diffraction element. There is no need to add more lenses to converge the light beam, which can improve the energy utilization rate. The diffraction element can specifically adopt a concave flat-field holographic grating, which is a concave reflective grating. The flat-field holographic grating can distribute the spectrum after diffraction splitting on a plane, which is convenient for receiving and detecting using a planar detection element array.

[0041] The generated diffraction light includes multiple orders of diffraction light, and any order of diffraction light includes different wavelength channel lights belonging to the diffraction order. According to the diffraction principle, each order of diffraction light has a corresponding exit angle, and different wavelength channel lights of the same diffraction order have corresponding exit angles. In practical applications, the exit angle of the selected order light, the exit angle of the different wavelength channel lights in the selected order light, and the exit angle of the non-selected order light can be calculated according to the dispersion equation for the diffraction element, so as to further arrange the various detection elements of the detection module and the extinction component accordingly according to each exit angle. The dispersion equation is expressed as: d*(sin(θ)+sin(β))=m*λ; wherein d represents the grating constant of the diffraction element, θ represents the incident angle of the light beam to be measured incident on the diffraction element, β represents the exit angle of the diffraction light, m ​​represents the diffraction order, and λ represents the wavelength.

[0042] In some embodiments, a plurality of extinction components are included, and the diffracted light includes multiple levels of non-selected order light, and the multiple levels of non-selected order light have different exit angles, and the plurality of extinction components are respectively arranged corresponding to the exit angles of the non-selected order light of different orders. For the non-selected order light of different exit angles generated by diffraction, corresponding extinction components are respectively arranged, and the extinction components correspond to the exit angles of the corresponding non-selected order light. The extinction components can be arranged on the exit path of the corresponding non-selected order light, and the corresponding non-selected order light is extincted by the extinction components. Therefore, the light measuring device reduces the influence of stray light on analysis and detection by extinction processing the multipolar non-selected order light generated by diffraction.

[0043] In this embodiment, the structure of the extinction component is not limited. In some embodiments, the extinction component includes an extinction cavity, so that non-selected order light is incident and trapped in the extinction cavity. After the non-selected order light enters the extinction cavity, it is reflected multiple times by the inner surface of the extinction cavity, scattered, lost, and attenuated, and is trapped in the extinction cavity. For example, reference may be made to Figure 1, which is a schematic diagram of a biochemical analysis device provided in an embodiment. As shown in the figure, the biochemical analysis device is provided with a photometric device, and the photometric device includes a diffraction element 4 and a detection module 7, and is also provided with a first extinction cavity 5 and a second extinction cavity 6, and the first extinction cavity 5 and the second extinction cavity 6 are set at different positions. The light beam to be measured is incident on the diffraction element 4 and diffracted, and the selected order light generated is incident on the detection module 7, so that a non-selected order light generated is incident on the first extinction cavity 5, and another order of non-selected order light generated is incident on the second extinction cavity 6.

[0044] In some embodiments, an opening is provided at one end of the extinction cavity, and the extinction cavity extends in the depth direction, so that the non-selected order light is incident on the opening and enters the extinction cavity, and after entering the extinction cavity, it is trapped in the extinction cavity after multiple reflections on the inner surface of the extinction cavity. The opening of the extinction cavity can be set corresponding to the exit angle of the non-selected order light, and the opening of the extinction cavity can be set on the exit path of the non-selected order light, so that the non-selected order light emitted from the diffraction element 4 is just incident on the opening of the extinction cavity and enters the extinction cavity. As shown in FIG1 , an opening is provided on one side of the first extinction cavity 5, and an opening is provided on one side of the second extinction cavity 6.

[0045] In some embodiments, the inner surface of the extinction cavity is absorptive to non-selected order light, and the non-selected order light entering the extinction cavity is absorbed when incident on the inner surface of the extinction cavity, so that the non-selected order light entering the extinction cavity is reflected multiple times by the inner surface of the extinction cavity, and a large part of the light is absorbed, thereby achieving an extinction effect. In some embodiments, an extinction layer absorptive to non-selected order light may be provided on the inner surface of the extinction cavity, and the extinction layer may be, but is not limited to, an extinction layer formed of a black material.

[0046] In some embodiments, the at least one detection element is respectively arranged corresponding to the exit angles of different wavelength channel lights in the selected order light. The detection module 7 may also include: at least one first slit, the first slit of the at least one first slit is arranged in one-to-one correspondence with the detection element of the at least one detection element, the first slit is arranged on the light incident side of the corresponding detection element, and is used to allow the corresponding wavelength channel light in the selected order light to pass through the first slit and be incident on the corresponding detection element.

[0047] The first slit is arranged corresponding to the detection element, and the detection element and the first slit are arranged corresponding to the exit angle of the corresponding wavelength channel light in the selected order light. The first slit allows the corresponding wavelength channel light in the selected order light to pass through and be incident on the corresponding detection element, and screens out the corresponding wavelength channel light in the selected order light, and blocks the non-corresponding wavelength channel light and the non-selected order light to prevent these lights from being incident on the corresponding detection element. For example, reference may be made to Figures 2 and 3. Figure 2 is a structural schematic diagram of a detection module of a light measuring device provided in an embodiment, and Figure 3 is an exploded schematic diagram of the detection module shown in Figure 2. As shown in the figure, the detection module 7 includes a detection element array 74 and a first slit array 72. The detection element array 74 includes a plurality of detection elements 75. The first slit array 72 includes a plurality of first slits 77. The first slits 77 of the first slit array 72 are arranged in a one-to-one correspondence with the detection elements 75 of the detection element array 74.

[0048] In this embodiment, the width of each first slit 77 of the first slit array 72 is not limited. In practical applications, it can be set according to the spot size of the corresponding wavelength channel light in the diffraction light generated by the diffraction element 4 and the detection accuracy requirement for the single wavelength channel light.

[0049] In some embodiments, the detection module 7 may also include: at least one second slit, the second slit of the at least one second slit is arranged in a one-to-one correspondence with the detection element of the at least one detection element, the second slit is arranged on the side of the corresponding first slit close to the detection element, and is used to allow light from the corresponding first slit to pass through the second slit and be incident on the corresponding detection element, and to block light from other first slits from being incident on the corresponding detection element, and the other first slits refer to other first slits except the first slit corresponding to the second slit.

[0050] For example, referring to FIG. 2 and FIG. 3 , the second slit 76 is arranged corresponding to the detection element 75, and the detection element 75, the second slit 76, and the first slit 77 are all arranged corresponding to the exit angle of the corresponding wavelength channel light in the selected order light. The selected order light from the diffraction element 4 is incident on the detection module 7, wherein the different wavelength channel lights are respectively incident on each first slit 77, and any wavelength channel light is incident on the corresponding first slit 77 and passes through the corresponding first slit 77, and any second slit 76 allows the light from the corresponding first slit 77 to pass through and be incident on the corresponding detection element 75, and the second slit 76 blocks the light from other first slits 77 from being incident on the corresponding detection element 75.

[0051] Before the light of any wavelength channel incident on the detection module 7 is incident on the detection element 75, it will be reflected and generate stray light when passing through other components of the detection module 7. These stray lights may be incident on other detection elements 75, causing crosstalk between channels. For example, the light from other first slits 77 generates stray light correspondingly. When these stray lights are incident on the detection element 75 corresponding to the first slit 77, they will cause interference. Therefore, the light measuring device is provided with a second slit 76 on the light incident side of the detection element 75, and the second slit 76 is used to block the light from other first slits 77 from being incident on the detection element 75 corresponding to the second slit 76. For example, the stray light generated by the light from other first slits 77 can be blocked from being incident on the corresponding detection element 75, thereby reducing the crosstalk between the detection elements 75. Referring to FIG. 2 and FIG. 3, the detection module 7 also includes a second slit array 73, and the second slit array 73 includes a plurality of second slits 76. The second slits 76 of the second slit array 73 are arranged in one-to-one correspondence with the detection elements 75 of the detection element array 74.

[0052] In some embodiments, the sidewalls of the second slits 76 are used to block light from other first slits 77 from being incident on the corresponding detection element 75. Stray light from other first slits 77 can be blocked by the sidewalls of the second slits 76, thereby blocking the stray light from being incident on the detection element 75. The thickness of the second slit 76 may be greater than a preset value, and the thickness of the second slit 76 satisfies the corresponding conditions, so that the sidewalls of the second slits 76 can block light from other first slits 77 from being incident on the corresponding detection element 75.

[0053] In some embodiments, the sidewall of the second slit 76 is absorptive to light, and the light from other first slits 77 incident on the sidewall of the second slit 76 will be absorbed, thereby blocking the crosstalk light from being incident on the detection element 75. In some embodiments, the sidewall surface of the second slit 76 is blackened and has a certain light absorption function, and the crosstalk light between the detection elements 75 will be absorbed when passing through the sidewall, thereby effectively blocking the reflection of part of the stray light between the detection elements and reducing the crosstalk between channels.

[0054] The width of the second slit 76 is greater than the width of the corresponding first slit 77, so as to ensure that the corresponding wavelength channel light from the corresponding first slit 77 can pass through the second slit 76. The thickness of the second slit 76 is greater than the thickness of the corresponding first slit 77, so that the second slit 76 can block the light from other first slits 77 from being incident on the corresponding detection element 75. In a specific example, the thickness of the second slit 76 ranges from 0.5 mm to 0.7 mm, and the thickness of the first slit 77 ranges from 0.1 mm to 0.3 mm.

[0055] In the actual application of biochemical analysis, for the spectroscopic detection method using diffraction elements, the diffracted light is a wavelength continuous spectrum. For the selected order diffracted light, only a few wavelength channels are used for the detection of the object to be tested, such as selecting 8-16 wavelength channels, and the other unselected spectra can be regarded as stray light. The detection elements corresponding to the selected wavelength channel detection are relatively small, and it is easy to have crosstalk between channels. Therefore, the light measuring device can reduce the influence of these stray lights on analysis and detection by setting the first slit and the second slit on the light incident side of the detection element.

[0056] In some embodiments, the at least one detection element is respectively arranged corresponding to the exit angles of different wavelength channel lights in the selected order light. The detection module 7 may also include: at least one filter element, arranged on the light incident side of the at least one detection element, the filter element is used to allow the corresponding wavelength channel light in the selected order light to pass through and be incident on the corresponding detection element. The filter element can allow the corresponding wavelength channel light in the selected order light to pass through and be incident on the corresponding detection element, and prevent other wavelength channel lights in the selected order light that do not correspond to the corresponding detection element from passing through, and the filter element plays a role in preliminary filtering of stray light. In addition, the filter element also plays a protective function to prevent the detection element 75 from being directly exposed to the air. For example, referring to Figures 2 and 3, the detection module 7 also includes a filter element array 71, and the filter element array 71 includes a plurality of filter elements 78, any of which is arranged corresponding to the plurality of detection elements 75 in the detection element array 74. The filter element 78 can be, but is not limited to, an absorption filter, and can be a filter with a relatively large bandwidth. The filter element 78 may be a colored glass filter.

[0057] The detection element 75 may be, but is not limited to, a photodiode (PD).

[0058] The photometric device of this embodiment eliminates stray light introduced by the use of diffraction elements as much as possible by providing an extinction component, a filter element array, a first slit array and a second slit array, so that the photometric device of the biochemical analysis equipment can meet the requirements of multi-channel simultaneous measurement and fast detection speed while having the advantages of low stray light, thereby improving its detection upper limit and accuracy when detecting high absorbance solutions.

[0059] This embodiment also provides a biochemical analysis device, including:

[0060] The light source device 1 is used to emit light, so that the light is irradiated to the object to be measured, so that the object to be measured generates a light beam to be measured;

[0061] The light measuring device described in any one of the above items is arranged at one side of the object to be measured, so that the light beam to be measured is incident on the diffraction element 4 of the light measuring device.

[0062] In the biochemical analysis equipment of this embodiment, the light measuring device is provided with an extinction component on the light output side of the diffraction element, and uses the extinction component to extinct the generated non-selected order light to reduce the influence of the stray light on the analysis and detection.

[0063] In some embodiments, the biochemical analysis equipment may further include: a first lens group 2, which is disposed between the light source device 1 and the object to be tested, and is used to collimate the emitted light of the light source device 1 and converge the collimated light to the object to be tested. By first collimating the emitted light of the light source device 1 through the first lens group 2, as much emitted light of the light source device 1 as possible can be collected. In the case where the emitted light of the light source device 1 is divergent light, as much light within a certain angle as possible can be collected. For example, referring to FIG. 1, a first lens group 2 is disposed between the light source device 1 and the object to be tested (the object to be tested is not shown in FIG. 1, and the object to be tested is between the first lens group 2 and the second lens group 3).

[0064] In some embodiments, the biochemical analysis equipment may further include: a second lens group 3, which is disposed between the object to be measured and the light measuring device, and is used to collimate the light beam to be measured from the object to be measured, and converge the collimated light beam to be measured, so that the converged light beam to be measured is incident on the diffraction element 4. The light from the object to be measured passes through the second lens group 3, and the second lens group 3 first collimates the light beam to be measured from the object to be measured, so as to collect as much light from the object to be measured as possible. The second lens group 3 further converges the collimated light beam to be measured, so that the converged light beam to be measured is incident on the diffraction element 4, which helps to improve the monochromaticity and resolution of the monochromatic spectrum generated by the light beam to be measured after passing through the diffraction element 4. The size of the spot of the light beam to be measured incident on the diffraction element 4 corresponds to the size of the monochromatic light convergence spot produced after the diffraction and spectral splitting by the diffraction element 4. Therefore, the smaller the spot of the light beam to be measured incident on the diffraction element 4, the smaller the monochromatic light convergence spot produced after the diffraction and spectral splitting by the diffraction element 4, the smaller the overlapping area between the monochromatic light spot and the monochromatic light spot of the adjacent wavelength, and the better the monochromaticity and resolution of the monochromatic spectrum.

[0065] The light source device 1 can be, but is not limited to, a halogen light source. The halogen light source is a thermal radiation light source, and its emitted light is mixed white light. During biochemical detection, the mixed white light is irradiated onto the object to be detected, and the light passing through the object to be detected is incident on the diffraction element 4. The diffraction element 4 diffracts the light from the object to be detected into a spectrum from short wave to long wave. The detection module 7 selects a single or multiple specific monochromatic wavelengths for detection, thereby realizing detection of the object to be detected.

[0066] The photometric device used in the biochemical analysis equipment of this embodiment can specifically eliminate the stray light introduced by the use of the diffraction element 4, wherein the specific extinction component can absorb the non-selected order spectrum through the extinction material and multiple reflections, and the first slit array 72 arranged according to the corresponding wavelength channel can block other non-selected spectra to prevent them from irradiating the plane of the detection element array 74; the second slit array 73 with a certain thickness added in front of the detection element array 74 can effectively block part of the stray light generated by the reflection of the detection element at the adjacent position, and reduce the crosstalk between channels. Thus, the biochemical analysis equipment meets the requirements of multi-channel simultaneous measurement, fast detection speed, and low stray light (≥8abs at 340nm), and improves its detection upper limit and its accuracy in detecting high absorbance solutions.

[0067] The above is a detailed introduction to a biochemical analysis device and a photometric device provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the present invention, the present invention can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.

Claims

1. A light measuring device, characterized in that: include: A diffraction element, used for diffracting the light beam to be measured when the light beam to be measured is incident on the diffraction element, so that the selected order light in the diffracted light is incident on the detection module; The detection module is arranged at the light-emitting side of the diffraction element and corresponds to the emission angle of the selected order light in the diffracted light, and includes at least one detection element arranged in sequence, and the at least one detection element is respectively used to detect different wavelength channel lights in the selected order light; The extinction component is arranged on the light-emitting side of the diffraction element and corresponds to the emission angle of the non-selected order light in the diffracted light, and is used to make the non-selected order light incident on the extinction component to perform extinction processing on the non-selected order light.

2. The light measuring device according to claim 1, characterized in that: It comprises a plurality of the extinction components, the diffracted light comprises a plurality of levels of non-selected level lights, the emission angles of the plurality of levels of non-selected level lights are different, and the plurality of the extinction components are respectively arranged corresponding to the emission angles of the non-selected level lights of different levels.

3. The light measuring device according to claim 1, characterized in that: The extinction component includes an extinction cavity, so that the non-selected order light is incident into and trapped in the extinction cavity.

4. The light measuring device according to claim 3, characterized in that: The inner surface of the extinction cavity is absorptive to the non-selected order light.

5. The light measuring device according to claim 3, characterized in that: An opening is provided at one end of the extinction cavity, and the extinction cavity extends in the depth direction, so that the non-selected order light is incident on the opening and enters the extinction cavity. After entering the extinction cavity, it is reflected multiple times by the inner surface of the extinction cavity and is trapped in the extinction cavity.

6. The light measuring device according to claim 1, characterized in that: The at least one detection element is respectively arranged corresponding to the emission angles of the different wavelength channel lights in the selected order light; The detection module also includes: At least one first slit, the first slit of the at least one first slit is arranged in a one-to-one correspondence with the detection element of the at least one detection element, and the first slit is arranged on the light incident side of the corresponding detection element, so as to allow the corresponding wavelength channel light in the selected order light to pass through the first slit and be incident on the corresponding detection element.

7. The light measuring device according to claim 6, characterized in that: The detection module also includes: At least one second slit, the second slit of the at least one second slit is arranged in a one-to-one correspondence with the detection element of the at least one detection element, the second slit is arranged on the side of the corresponding first slit close to the detection element, and is used to allow light from the corresponding first slit to pass through the second slit and be incident on the corresponding detection element, and block light from other first slits from being incident on the corresponding detection element, and the other first slits refer to other first slits except the first slit corresponding to the second slit.

8. The light measuring device according to claim 7, characterized in that: The sidewalls of the second slits are used to block light from other first slits from being incident on the corresponding detection element.

9. The light measuring device according to claim 7, characterized in that: The sidewalls of the second slit are light absorptive.

10. A biochemical analysis device, characterized in that: include: A light source device, used for emitting light, so that the light is irradiated to the object to be measured, so that the object to be measured generates a light beam to be measured; The photometric device according to any one of claims 1 to 9 is arranged on one side of the object to be measured, so that the light beam to be measured is incident on the diffraction element of the photometric device.