Preparation method of vaginal irrigation fluid

Abstract

The invention belongs to the technical field of flushing fluids, and particularly relates to a vaginal flushing fluid, which is prepared from the following raw materials in parts by mass: 25 to 35g of caulis sargentodoxae, 10 to 20g of herba patriniae, 10 to 20g of herba taraxaci, 10 to 20g of herba hedyotidis diffusae, 10 to 20g of herba scutellariae barbatae, 8 to 12g of radix paeoniae rubra and 2 to 5g of herba menthae. The preparation method comprises the following steps: step 1, preparing a sodium bicarbonate solution; step 2, preparing a mixed liquid medicine; and 3, introducing the mixed liquid medicine prepared in the step 2 into the sodium bicarbonate solution prepared in the step 1, oscillating and mixing, and canning to obtain the vaginal irrigation fluid. According to the flushing fluid, due to the arrangement of the medicine components such as the sargentgloryvine stem, the herba patriniae, the dandelion, the oldenlandia diffusa, the sculellaria barbata, the radix paeoniae rubra and the mint, the flushing fluid can effectively regulate the PH value of the vagina of a patient, the treatment effect on vagina inflammation can be guaranteed, and therefore the use effect of the flushing fluid is improved.

Description

Technical Field

[0001] The invention relates to the technical field of flushing liquid, and in particular to a preparation method of vaginal flushing liquid. Background Art

[0002] Gynecological diseases such as vaginitis are common and frequently occurring diseases that are usually difficult to cure, causing great inconvenience to normal life and work.

[0003] At present, there are a wide variety of gynecological drugs on the market, such as: Jieryin, Fuyanjie, Fuke Qianjin Wash, etc. Patent information also introduces gynecological antibacterial drugs. For example, the Chinese invention application with application number 201110368457.4 discloses a nano-grade gynecological wash and its preparation method. The particle size of the wash is 1 to 100nm, and it is made of the following raw materials in mass percentage: 20% to 40% surfactant, 1% to 10% co-surfactant, 0.2% to 5% oil phase, 1% to 20% myrrh oil, 0.02% to 5% nano silver sol, 1% to 5% aloe extract, 0.1% glacial acetic acid, and the remainder is purified water. The sum of the mass percentages of the above raw materials is 100%.

[0004] However, the existing dosing solution has a relatively simple drug composition, and the dosing solution cannot effectively regulate the pH value of the patient's vagina, and the treatment effect on vaginal inflammation is poor, thereby affecting the use effect of the dosing solution. Summary of the invention

[0005] 1. Technical issues to be solved

[0006] The purpose of the present invention is to solve the problem that the flushing liquid in the prior art cannot effectively regulate the pH value of the patient's vagina and has a poor treatment effect on vaginal inflammation, and a method for preparing a vaginal flushing liquid is proposed.

[0007] 2. Technical solution

[0008] In order to achieve the above object, the present invention adopts the following technical solutions:

[0009] A vaginal douching liquid comprises the following raw materials in parts by weight: 25-35g of red safflower, 10-20g of patrinia herb, 10-20g of dandelion, 10-20g of oldenlandia diffusa, 10-20g of scutellaria barbata, 8-12g of red peony root and 2-5g of mint.

[0010] Preferably, the following raw materials are included in parts by mass: 25g of red safflower, 20g of Patrinia scabra, 10g of dandelion, 20g of oldenlandia diffusa, 10g of Scutellaria barbata, 12g of red peony root and 2g of mint.

[0011] Preferably, the following raw materials are included in parts by mass: 35g of red safflower, 10g of Patrinia scabra, 20g of dandelion, 10g of Hedyotis diffusa, 20g of Scutellaria barbata, 8g of red peony root and 5g of mint.

[0012] Preferably, the following raw materials are included in parts by mass: 30g of red safflower, 15g of Patrinia scabra, 15g of dandelion, 15g of Hedyotis diffusa, 15g of Scutellaria barbata, 10g of red peony root and 3g of mint.

[0013] The present invention also proposes a method for preparing a vaginal douching solution, comprising the following steps:

[0014] Step 1: Preparation of sodium bicarbonate solution: according to the required volume and concentration of the solution, add a certain amount of sodium bicarbonate and water into a preparation container, stir and mix to dissolve, and then prepare a sodium bicarbonate solution;

[0015] Step 2: Preparation of mixed medicinal liquid: taking certain weight portions of red safflower, Patrinia scabra, dandelion, oldenlandia diffusa, Scutellaria barbata, red peony root and mint, washing them, crushing and stirring them in a grinder, and then boiling them in a casserole to obtain a mixed medicinal liquid;

[0016] Step 3: The mixed drug solution prepared in step 2 is then introduced into the sodium bicarbonate solution in step 1, shaken and mixed, and then bottled to obtain a vaginal washing solution.

[0017] Preferably.

[0018] Preferably, in step 2, the rotation speed of the pulverizer is 2000-4000 rpm, and the pulverizing time is 5-10 min.

[0019] Preferably, in step 3, the mixed medicinal solution and the sodium bicarbonate solution are mixed in an oscillating mixer, and the oscillation frequency of the oscillating mixer is 2800 times / minm.

[0020] 3. Beneficial effects

[0021] Compared with the prior art, the advantages of the present invention are:

[0022] 1. In the present invention, by setting up drug components such as red vine, Patrinia scabra, dandelion, oldenlandia diffusa, Scutellaria barbata, red peony root and mint, the flushing solution can effectively regulate the pH value of the patient's vagina, ensure the treatment effect of vaginal inflammation, and thus improve the use effect of the flushing solution.

[0023] 2. In the present invention, red caulis has the effects of regulating qi and activating blood circulation, dispelling wind and killing insects, reducing swelling and dispersing nodules. Pharmacological studies have confirmed that it has antibacterial and anti-inflammatory, antioxidant, anti-tumor, antiviral, and anti-allergic effects;

[0024] 3. In the present invention, Patrinia patriniae has the effects of clearing away heat and detoxifying, reducing swelling and draining pus, removing blood stasis and relieving pain, and pharmacological experiments have confirmed that it has antibacterial and anti-inflammatory, anti-tumor and sedative effects;

[0025] 4. In the present invention, dandelion has the effects of clearing away heat and detoxifying, eliminating carbuncle and swelling, and treating sore. Pharmacological experiments have confirmed that this medicine has broad-spectrum antibacterial effect, immunomodulatory effect, and anti-tumor effect;

[0026] 5. In the present invention, Hedyotis diffusa has the effects of clearing away heat and detoxifying, promoting dampness and relieving stranguria, and pharmacological studies have confirmed that it has anti-inflammatory, anti-cancer, antioxidant, anti-infective and immunomodulatory effects;

[0027] 6. In the present invention, Scutellaria barbata has the effects of clearing away heat and detoxifying, removing blood stasis and promoting diuresis. Pharmacological studies have confirmed that it has the effects of anti-cancer, anti-bacterial, inhibiting the growth and reproduction of tumor cells, inducing tumor cell apoptosis, enhancing immunity, and anti-viral, anti-oxidation, and anti-mutagenicity;

[0028] 7. In the present invention, red peony root has the effects of clearing away heat and detoxifying, promoting blood circulation and removing blood stasis, and pharmacological experiments show antibacterial and antiviral effects, and its effective ingredients show neuroprotective, anti-depressant, blood sugar and blood lipid regulation, anti-tumor, antioxidant and immune regulation effects;

[0029] 8. In the present invention, peppermint has the effects of dispelling wind and clearing away heat, dilating skin capillaries, and slowly delivering drugs into the intradermal cells, thus playing the role of cooling, relieving pain and relieving itching. Its peppermint oil extract has potential therapeutic uses for the gastrointestinal effects caused by cancer radiotherapy. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 The present invention is a schematic flow chart of a method for preparing a vaginal washing solution. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0032] Embodiment 1:

[0033] In this embodiment, a vaginal washing solution includes the following raw materials in parts by weight: 25-35g of red vine, 10-20g of Patrinia scabra, 10-20g of dandelion, 10-20g of Hedyotis diffusa, 10-20g of Scutellaria barbata, 8-12g of red peony root, and 2-5g of mint.

[0034] In this embodiment, refer to Figure 1 , a method for preparing a vaginal douching solution, comprising the following steps:

[0035] Step 1: Preparation of sodium bicarbonate solution: according to the required volume and concentration of the solution, add a certain amount of sodium bicarbonate and water into the preparation container, stir and mix to dissolve, and then prepare a sodium bicarbonate solution, the concentration of which is 20 g / L;

[0036] Step 2: Preparation of mixed medicinal liquid: taking certain weight parts of red safflower, Patrinia scabra, dandelion, oldenlandia diffusa, Scutellaria barbata, red peony root and mint, washing them, crushing and stirring them in a grinder, and then boiling them in a casserole to obtain a mixed medicinal liquid, the speed of the grinder is 2000-4000rpm, and the crushing time is 5-10min;

[0037] Step 3: The mixed drug solution prepared in step 2 is then introduced into the sodium bicarbonate solution in step 1, shaken and mixed, and then canned to obtain a vaginal washing solution. The mixed drug solution and the sodium bicarbonate solution are mixed in a shaking mixer, and the shaking frequency of the shaking mixer is 2800 times / minm.

[0038] In this embodiment, by setting up drug components such as red vine, Patrinia scabra, dandelion, oldenlandia diffusa, Scutellaria barbata, red peony root and mint, the flushing solution can effectively regulate the pH value of the patient's vagina, ensure the treatment effect of vaginal inflammation, and thus improve the use effect of the flushing solution.

[0039] In this embodiment, the main components of the red vine include rhubarb, rhubarb methyl ether, β-sitosterol, stearic acid, salvinia glycosides, rhubarb phenol, vanillic acid, red vine polysaccharide and protocatechuic acid and other chemical components; it has the effects of regulating qi and promoting blood circulation, dispelling wind and killing insects, and reducing swelling and dispersing nodules. Pharmacological studies have confirmed that it has antibacterial and anti-inflammatory, antioxidant, anti-tumor, antiviral, anti-allergic and other effects;

[0040] In this embodiment, the herb contains choline, tartaric acid, bitter elements and other chemical substances, which play an important role in the pharmacological effects of the herb, and have the effects of clearing away heat and detoxifying, reducing swelling and draining pus, removing blood stasis and relieving pain. Pharmacological experiments have confirmed that it has antibacterial and anti-inflammatory, anti-tumor and sedative effects.

[0041] In this embodiment, dandelion contains taraxacin, taraxacinol, choline, inulin, organic acid and anti-tumor active substance selenium, etc. These substances are active ingredients unique to dandelion and have antibacterial and anti-inflammatory effects. Pharmacological experiments have confirmed that this drug has broad-spectrum antibacterial, immunomodulatory and anti-tumor effects.

[0042] In this embodiment, Hedyotis diffusa contains ursolic acid and oleanolic acid. These two compounds not only have antibacterial and anti-inflammatory effects, but also have anti-cancer and enzyme-lowering effects, and can inhibit the growth of 180 strains of sarcoma. Hedyotis diffusa also contains a variety of trace elements, such as iron (Fe), manganese (Mn), titanium (Ti), magnesium (Mg), aluminum (Al), silicon (Si), calcium (Ca), etc.; among them, the Ti element can stimulate phagocytes, thereby enhancing the body's immune ability; pharmacological studies have confirmed that it has anti-inflammatory, anti-cancer, antioxidant, anti-infective, and immunomodulatory effects;

[0043] In this embodiment, Scutellaria barbata contains flavonoids, polysaccharides, diterpenoids and porphyrins, among which flavonoids have multiple pharmacological activities and can achieve anti-tumor effects through different mechanisms; chlorophyll belongs to a magnesium porphyrin cyclic complex, and its porphyrin ring structure is easily combined with a complex with a polycyclic structure (such as a planar aromatic carcinogen) by a non-covalent bond, and finally forms an inactive complex and loses pathogenicity, thereby achieving an anti-tumor effect; pharmacological studies have confirmed that it has anti-cancer, antibacterial, tumor cell growth and reproduction inhibition, tumor cell apoptosis induction, immunity enhancement, anti-viral, antioxidant, anti-mutagenic and other effects;

[0044] In this embodiment, red peony root mainly contains terpenes and their glycosides, flavonoids and their glycosides, tannins, phenolic acids and volatile oils, among which phenolic acid compounds such as gallic acid, protocatechuic acid and benzoic acid are important components of red peony root, which have the effects of clearing away heat and detoxifying, promoting blood circulation and dispersing blood stasis, and pharmacological experiments have antibacterial and antiviral effects, and its effective ingredients show neuroprotective, antidepressant, blood sugar and blood lipid regulation, anti-tumor, antioxidant and immune regulation effects;

[0045] In the present embodiment, mint mainly contains menthol, menthol hydrazone and menthol, among which menthol is one of the main active ingredients of mint and the source of the unique flavor of mint. Menthol has a refreshing feeling and is often used to make products such as chewing gum, toothpaste, and mouth fresheners. In addition, menthol also has antibacterial and antiviral effects, and can be used to treat diseases such as colds and coughs; menthol hydrazone: another important component of mint, with multiple pharmacological effects such as analgesia, anti-inflammatory, and antibacterial. Menthol hydrazone can be used to relieve discomfort symptoms such as headaches and muscle aches, and can also stimulate the gastrointestinal tract, promote digestion, and relieve gastrointestinal discomfort; menthol: one of the main volatile oil components of mint, with a unique cool fragrance. Menthol has analgesic, anti-inflammatory, and bactericidal effects, and is widely used in the fields of medicine and food. In addition, menthol can stimulate the skin and promote blood circulation. It is often used to make massage oils and body care products. It has the effects of dispelling wind and heat, dilating skin capillaries, and slowly allowing drugs to enter the intradermal cells, playing a cooling, analgesic and itching role. Its peppermint oil extract has potential therapeutic uses for the gastrointestinal effects of cancer radiotherapy.

[0046] Embodiment 2:

[0047] It has the implementation content of the above-mentioned embodiment, wherein the specific implementation of the above-mentioned embodiment can refer to the above description, and the embodiment here will not be repeated in detail; and in the embodiment of the present application, it is different from the above-mentioned embodiment in that:

[0048] In this embodiment, a vaginal washing solution includes the following raw materials in parts by weight: 25 g of red safflower, 20 g of patrinia herb, 10 g of dandelion, 20 g of oldenlandia diffusa, 10 g of barbata, 12 g of red peony root and 2 g of mint.

[0049] Embodiment 3:

[0050] It has the implementation content of the above-mentioned embodiment, wherein the specific implementation of the above-mentioned embodiment can refer to the above description, and the embodiment here will not be repeated in detail; and in the embodiment of the present application, it is different from the above-mentioned embodiment in that:

[0051] In this embodiment, a vaginal washing solution includes the following raw materials in parts by weight: 35 g of red safflower, 10 g of Patrinia scabra, 20 g of dandelion, 10 g of Hedyotis diffusa, 20 g of Scutellaria barbata, 8 g of red peony root and 5 g of mint.

[0052] Embodiment 4:

[0053] It has the implementation content of the above-mentioned embodiment, wherein the specific implementation of the above-mentioned embodiment can refer to the above description, and the embodiment here will not be repeated in detail; and in the embodiment of the present application, it is different from the above-mentioned embodiment in that:

[0054] In this embodiment, a vaginal washing solution includes the following raw materials in parts by weight: 30 g of red safflower, 15 g of patrinia herb, 15 g of dandelion, 15 g of oldenlandia diffusa, 15 g of Scutellaria barbata, 10 g of red peony root and 3 g of mint.

[0055] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A vaginal douching solution, characterized in that: The invention comprises the following raw materials in parts by weight: 25-35g of red vine, 10-20g of Patrinia scabra, 10-20g of Taraxacum mongolicum, 10-20g of Hedyotis diffusa, 10-20g of Scutellaria barbata, 8-12g of red peony root and 2-5g of mint.

2. A vaginal washing solution according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 25 g of red vine, 20 g of Patrinia scabra, 10 g of Taraxacum mongolicum, 20 g of Hedyotis diffusa, 10 g of Scutellaria barbata, 12 g of Paeonia lactiflora and 2 g of mint.

3. A vaginal douching solution according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 35 g of red vine, 10 g of Patrinia scabra, 20 g of Taraxacum mongolicum, 10 g of Hedyotis diffusa, 20 g of Scutellaria barbata, 8 g of Paeonia lactiflora and 5 g of mint.

4. A vaginal washing solution according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 30 g of red vine, 15 g of Patrinia scabra, 15 g of Taraxacum mongolicum, 15 g of Hedyotis diffusa, 15 g of Scutellaria barbata, 10 g of Paeonia lactiflora and 3 g of mint.

5. A method for preparing a vaginal douching solution according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1: Preparation of sodium bicarbonate solution: according to the required volume and concentration of the solution, add a certain amount of sodium bicarbonate and water into a preparation container, stir and mix to dissolve, and then prepare a sodium bicarbonate solution; Step 2: Preparation of mixed medicinal liquid: taking certain weight portions of red safflower, Patrinia scabra, dandelion, oldenlandia diffusa, Scutellaria barbata, red peony root and mint, washing them, crushing and stirring them in a grinder, and then boiling them in a casserole to obtain a mixed medicinal liquid; Step 3: The mixed drug solution prepared in step 2 is then introduced into the sodium bicarbonate solution in step 1, shaken and mixed, and then bottled to obtain a vaginal washing solution.

6. The method for preparing a vaginal douching solution according to claim 5, characterized in that: The concentration of the sodium bicarbonate solution in step 1 is 20 g / L.

7. The method for preparing a vaginal douching solution according to claim 5, characterized in that: In step 2, the rotation speed of the pulverizer is 2000-4000 rpm, and the pulverization time is 5-10 min.

8. The method for preparing a vaginal douching solution according to claim 5, characterized in that: In step 3, the mixed medicinal solution and the sodium bicarbonate solution are mixed in an oscillating mixer, and the oscillation frequency of the oscillating mixer is 2800 times / minm.

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