PICC (Peripherally Inserted Central Catheter) system for preventing fibrin sheath

Abstract

The invention discloses a PICC (Peripherally Inserted Central Catheter) system for preventing fibrin sheath, which comprises a PICC tube body and a resistance measuring device, the PICC tube body is provided with a resistance detection head which is used for measuring the resistance of blood when the PICC tube body is inserted into a superior vena cava, and the resistance detection head is connected with the resistance measuring device. When the resistance measuring equipment detects that the resistance of the blood detected by the resistance detecting head exceeds an initially set alarm value, it is indicated that a fibrin sheath is formed outside the PICC tube body, the resistance measuring equipment sends out alarm information, and medical staff immediately injects heparin sodium into the PICC tube body to dissolve the fibrin sheath after receiving the alarm information; the characteristic that blood and tissue resistance values are different is utilized, when the resistance values change, the buzzer gives an alarm to remind medical staff that fibrin sheaths are formed in the medical staff, the medical staff intervenes and eliminates the fibrin sheaths as soon as possible, and pain of a patient during tube drawing is relieved by preventing formation of the fibrin sheaths.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a PICC system for preventing fibrin sheath. Background Art

[0002] PICC (Peripherally Inserted Central Venous Catheters) is a central venous catheter placed through peripheral vein puncture. It uses a catheter to puncture the vein of the peripheral arm. The catheter directly reaches the large vein close to the heart, avoiding direct contact between chemotherapy drugs and arm veins. In addition, the blood flow rate of large veins is very fast, which can quickly dilute chemotherapy drugs and prevent drugs from irritating blood vessels. Therefore, it can effectively protect upper limb veins, reduce the occurrence of phlebitis, relieve patients' pain, and improve patients' quality of life.

[0003] The fibrin sheath is a membrane of multiple components wrapped on the surface of the PICC catheter, which leads to abnormal catheter function and difficulty in extubation. Studies have shown that the incidence of fibrin sheath in PICC catheters is greater than 38%. Because the fibrin sheath wraps the catheter, the catheter becomes thicker. During the process of extubation, the blood vessels passing through become thinner and thinner, causing difficulty in extubation. At the same time, if there are more fibrin sheaths, they will adhere to the blood vessels, causing pain, anxiety, fear, etc. in patients during extubation. The shedding of fibrin sheaths in the blood vessels can also easily cause blood vessel blockage. In severe cases, thrombi can form, which has a great impact on the life and health of patients. Therefore, how to avoid the occurrence of fibrin sheaths is of great medical significance. The Chinese utility model patent with application number "202322287747.7" discloses "a PICC catheter that is easy to dissolve fibrin sheaths". A thin film is wrapped around the outside of the PICC tube, and a hole is opened in the film. Urokinase that dissolves the fibrin sheath is injected between the film and the PICC catheter through a mechanism to dissolve the fibrin sheath. Due to the hole in the film, blood can easily enter between the film and the PICC catheter, coagulate, and form a fibrin sheath more easily. At the same time, the outer film increases the diameter of the PICC catheter, which makes it difficult to insert the catheter into the originally very thin blood vessels or hinders the blood flow in the blood vessels. If there is a large amount of fibrin sheath, there is also the problem of incomplete dissolution. At the same time, when the PICC tube is implanted into the patient's body, the length of the PICC tube needs to be adjusted according to the actual situation of the patient. Generally, a part of the end is cut off, so that the film will be cut and it is only suitable for people with a specific length. Summary of the invention

[0004] In order to solve the defects of the prior art, the present invention provides a PICC system for preventing fibrin sheath.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions:

[0006] The present invention discloses a PICC system for preventing fibrin sheath, comprising a PICC tube body and a resistance measuring device, wherein the PICC tube body is provided with a resistance detection head for measuring the resistance of blood when the PICC tube body is inserted into the superior vena cava, and the resistance detection head is connected to the resistance measuring device, and when the resistance measuring device detects that the resistance of the blood detected by the resistance detection head exceeds an initially set warning value, it indicates that a fibrin sheath is formed outside the PICC tube body, and the resistance measuring device sends out an alarm message, and after receiving the alarm message, medical staff immediately injects sodium heparin into the PICC tube body to dissolve the fibrin sheath.

[0007] As a preferred technical solution of the present invention, the resistance detection head includes a metal wire 1 and a metal wire 2 buried in the PICC tube body, the metal wire 1 and the metal wire 2 are arranged along the length direction of the PICC tube body, and the end faces of the metal wire 1 and the metal wire 2 extend out of the end face of the PICC tube body, and the metal wire 1 and the metal wire 2 are respectively connected to the positive electrode and the negative electrode of the resistance measuring device through the wire; the PICC tube body, the metal wire 1 and the metal wire 2 constitute the PICC tube assembly.

[0008] As a preferred technical solution of the present invention, the metal wire one and the metal wire two are both titanium metal wires.

[0009] As a preferred technical solution of the present invention, the resistance measuring device includes a device housing, a control board is provided in the device housing, a main control module, a resistance measuring module and a buzzer are provided on the control board, and the input end of the resistance measuring module is respectively connected to metal wire one and metal wire two, and the output end of the resistance measuring module is connected to the main control module, and the buzzer is connected to the main control module.

[0010] As a preferred technical solution of the present invention, the metal wire one and the metal wire two are provided with color distinguishing marks.

[0011] As a preferred technical solution of the present invention, the working method of the PICC system is as follows: before the PICC tube assembly is inserted, the length of the PICC tube assembly required by the patient is confirmed, and a portion of the length of the end of the PICC tube is cut off by a trimming tool so that the metal wire 1 and the metal wire 2 of the end of the PICC tube assembly are exposed to the end surface of the PICC tube body; after the insertion, the end of the PICC tube assembly is inserted into 1 / 3 of the superior vena cava, and the PICC tube assembly left outside the human body is fixed. At this time, the metal wire 1 and the metal wire 2 on the PICC tube assembly are connected according to the corresponding colors by a wire. The other end is connected to the resistance measuring device, and then the PICC tube assembly inserted into the blood vessel is used in conjunction with the resistance measuring device to accurately measure the resistance value of the blood. After a period of time, a fibrin sheath is formed on the surface of the PICC tube assembly, which covers the metal wire, resulting in a significant change in the resistance value measured by the metal wire. Once the set warning value is exceeded, the buzzer alarm sounds, and the medical staff injects heparin through the cavity inside the PICC tube to dissolve the fibrin sheath. If the fibrin sheath is not formed, the resistance value will not exceed the limit, so the buzzer will not alarm.

[0012] After chemotherapy is completed, sealing liquid is injected to seal the tube. Before the next chemotherapy, the PICC tube assembly and the resistance measuring device are connected with a wire and compared with the measured resistance value. If there is no change, continue to use it. If it changes greatly from the last measured value, a portion of the patient's blood can be drawn to measure the resistance value and then compare it with the resistance of the resistance measuring device. If the two are consistent, reset the warning value and perform chemotherapy. If the two are significantly different, it means that a fibrin sheath has formed in the PICC tube assembly. Inject heparin to dissolve the fibrin sheath. When the resistance values ​​of the two are consistent, it means that the fibrin sheath is completely dissolved. Then proceed with the subsequent chemotherapy process.

[0013] As a preferred technical solution of the present invention, the resistance measuring device calculates the specific resistance of different patients after the PICC tube assembly is inserted into the superior vena cava, and then sets the warning value according to this resistance and records it. When the patient's resistance value exceeds the warning value during chemotherapy, the resistance measuring device will alarm, and then remind the medical staff to inject sodium heparin to dissolve the fibrin sheath; the PICC tube is generally left in the patient's body for up to one year, so according to the patient's blood resistance value recorded before, when the patient undergoes subsequent chemotherapy, this resistance value can still be used. When the resistance value changes greatly, the patient's blood resistance value can be measured after blood sampling and compared with the resistance value when the PICC tube assembly is connected to the resistance measuring device. If the two are consistent, then the warning value is set again. If the difference between the two is large, it also means that a fibrin sheath has formed on the patient's PICC tube assembly, and the fibrin sheath needs to be dissolved before chemotherapy.

[0014] As a preferred technical solution of the present invention, the voltage input to the metal wire 1 and the metal wire 2 by the resistance measuring device does not exceed 1 volt.

[0015] The beneficial effects of the present invention are:

[0016] 1. This PICC system for preventing fibrin sheath uses metal wire 1 and metal wire 2 as positive and negative electrodes to contact blood and measure resistance. It uses the different resistance values ​​of blood and tissue. When the resistance value changes, the buzzer alarms to remind medical staff that fibrin sheath is forming inside. It can be detected at the earliest stage of formation, allowing medical staff to intervene early to eliminate the fibrin sheath.

[0017] 2. This type of PICC system that prevents the formation of fibrin sheaths can reduce the pain of patients during tube removal, and prevent the fibrin sheath from falling off inside the patient's blood vessels and forming thrombi. When implanting a PICC tube, it needs to be implanted in the superior vena cava. Due to the influence of different heights and arm spans, the PICC tube needs to be shortened to the required size according to the patient's condition before implantation. The metal wire runs through the entire length. When the tube is cut, the end will be exposed and can still be used normally. Different patients only need to trim the end of the PICC tube for use. Only by burying the metal wire inside the existing PICC catheter can the detection function be realized. Only the end is in contact with the blood inside the human body, and the contact area is small. At the same time, safer titanium metal materials can be selected. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention.

[0019] In the attached picture:

[0020] Figure 1 It is a structural schematic diagram of a PICC system for preventing fibrin sheath of the present invention;

[0021] Figure 2 An exploded view of a PICC system for preventing fibrin sheath according to the present invention;

[0022] Figure 3 An exploded view of the PICC tube assembly of the present invention;

[0023] Figure 4 An exploded view of the resistance measuring device of the present invention;

[0024] Figure 5 It is a structural schematic diagram of the end of the PICC tube assembly of the present invention;

[0025] Figure 6 This is a schematic diagram of the principle of preventing the formation of fibrin sheath according to the present invention.

[0026] In the figure: 1. PICC tube body; 2. resistance measuring device; 201. device housing; 202. main control module; 203. resistance measuring module; 204. buzzer; 3. resistance detection head; 301. metal wire 1; 302. metal wire 2; 4. wire. DETAILED DESCRIPTION

[0027] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0028] Example: Figure 1-6 As shown, a PICC system for preventing fibrin sheath of the present invention comprises a PICC tube body 1 and a resistance measuring device 2, and the PICC tube body 1 is provided with a resistance detection head 3 for measuring the resistance of blood when the PICC tube body 1 is inserted into the superior vena cava, and the resistance detection head 3 is connected to the resistance measuring device 2, and when the resistance measuring device 2 detects that the resistance of the blood detected by the resistance detection head 3 exceeds the initially set warning value, it indicates that a fibrin sheath is formed outside the PICC tube body 1, and the resistance measuring device 2 sends an alarm message, and after receiving the alarm message, the medical staff immediately injects sodium heparin into the PICC tube body 1 to dissolve the fibrin sheath. The present invention monitors the formation of the fibrin sheath by the resistance value, prevents it early, and prevents the difficulty of extubation after the formation of the fibrin sheath.

[0029] The resistance detection head 3 includes a metal wire 301 and a metal wire 302 buried in the PICC tube body 1, the metal wire 301 and the metal wire 302 are arranged along the length direction of the PICC tube body 1, and the end faces of the metal wire 301 and the metal wire 302 extend out of the end face of the PICC tube body 1, and the metal wire 301 and the metal wire 302 are respectively connected to the positive electrode and the negative electrode of the resistance measuring device 2 through the wire 4; the PICC tube body 1, the metal wire 301 and the metal wire 302 constitute the PICC tube assembly. Figure 5As shown, the metal wire is arranged at both ends of the cross section of the PICC body and wrapped inside the PICC tube body. Only the end is in contact with the blood. Considering that the PICC tube assembly will be cut at the end according to the length required by the patient, after cutting, the cross section of the metal wire can still be exposed to contact with the blood to achieve the function of measuring resistance. Metal wire one and metal wire two are used as positive and negative electrodes to contact the blood to measure resistance. The different resistance values ​​of blood and tissue are used. When the resistance value changes, the buzzer alarms to remind medical staff that fibrin sheath is formed inside. It can be detected at the initial stage of formation, so that medical staff can intervene early to eliminate the fibrin sheath. When implanting the PICC tube, it needs to be implanted into the superior vena cava. Due to the influence of different heights and arm spans, the PICC tube needs to be shortened to the required size according to the patient's condition before implantation. The metal wire runs through the entire length. When cutting the tube, the end will be exposed and can still be used normally. Different patients only need to trim the end of the PICC tube for use.

[0030] The metal wire 1 301 and the metal wire 2 302 are both titanium metal wires, which have little impact on the human body.

[0031] The resistance measuring device 2 comprises a device housing 201, a control board 201 is arranged in the device housing 201, a main control module 202, a resistance measuring module 203 and a buzzer 204 are arranged on the control board 201, and the input end of the resistance measuring module 203 is respectively connected to the metal wire 1 301 and the metal wire 2 302, and the output end of the resistance measuring module 2 is connected to the main control module 202, and the buzzer 204 is connected to the main control module 202. Figure 4 As shown in the figure, the control board is the core component of the resistance measuring device, which is mainly composed of the main control module, the resistance measuring module and the buzzer. The main control module controls the switch, voltage value, signal transmission, control of other modules, setting of resistance warning value, comparison between measured resistance and resistance warning value, etc. of the resistance measuring device. The resistance measuring module calculates the electrical properties of the metal wire transmitted by the wire into resistance value, and displays it on the screen through the main control module. The buzzer emits a buzzing sound to alarm, so that medical staff can hear it in time and take corresponding measures. The present invention utilizes the different resistance characteristics of blood and human tissue, embeds a first metal wire and a second metal wire inside the wall of a PICC tube as the positive and negative electrodes of an electrode, and measures the resistance of the blood. When a fibrin sheath is formed outside the PICC tube, the end faces of the two metal wires are covered, thereby causing a change in resistance. The resistance information is fed back to a main control module through a resistance measurement module on a control board inside the resistance measurement device, and then the main control module compares the resistance value with an initially set warning value. When the warning value is exceeded, the main control module controls a buzzer to sound an alarm. After hearing the alarm, medical staff promptly inject sodium heparin into the PICC tube to dissolve the fibrin sheath.

[0032] The metal wire 1 301 and the metal wire 2 302 are provided with color distinction marks, and the positive and negative poles are identified by color. In order to distinguish the positive and negative poles, the ends of the metal wire 1 and the metal wire 2 exposed from the PICC tube body are marked with different colors, red and black in this example.

[0033] The working method of the PICC system is as follows: before inserting the PICC tube assembly, confirm the length of the PICC tube assembly required by the patient, and use a trimming tool to cut off a part of the length of the PICC tube end, so that the metal wire 1 and the metal wire 2 of the end of the PICC tube assembly are exposed to the end surface of the PICC tube body; after inserting the tube, insert the end of the PICC tube assembly into 1 / 3 of the superior vena cava, fix the PICC tube assembly remaining outside the human body, and at this time, use a wire to connect the metal wire 1 and the metal wire 2 on the PICC tube assembly according to the corresponding color, and the other end Connected with the resistance measuring device, the PICC tube assembly inserted into the blood vessel is then used in conjunction with the resistance measuring device to accurately measure the resistance value of the blood. After a period of time, a fibrin sheath is formed on the surface of the PICC tube assembly, which covers the metal wire, causing a significant change in the resistance value measured by the metal wire. Once the set warning value is exceeded, the buzzer alarm sounds, and the medical staff injects heparin through the cavity inside the PICC tube to dissolve the fibrin sheath. If the fibrin sheath is not formed, the resistance value will not exceed the limit, so the buzzer will not alarm.

[0034] After chemotherapy is completed, sealing liquid is injected to seal the tube. Before the next chemotherapy, the PICC tube assembly and the resistance measuring device are connected with a wire and compared with the measured resistance value. If there is no change, continue to use it. If it changes greatly from the last measured value, a portion of the patient's blood can be drawn to measure the resistance value and then compare it with the resistance of the resistance measuring device. If the two are consistent, reset the warning value and perform chemotherapy. If the two are significantly different, it means that a fibrin sheath has formed in the PICC tube assembly. Inject heparin to dissolve the fibrin sheath. When the resistance values ​​of the two are consistent, it means that the fibrin sheath is completely dissolved. Then proceed with the subsequent chemotherapy process.

[0035] Among them, the resistance measuring device calculates the specific resistance of different patients after the PICC tube assembly is inserted into the superior vena cava, and then sets the warning value according to this resistance and records it. When the patient's resistance value exceeds the warning value during chemotherapy, the resistance measuring device will alarm, and then remind the medical staff to inject sodium heparin to dissolve the fibrin sheath; the PICC tube is generally left in the patient's body for up to one year, so according to the patient's blood resistance value recorded before, when the patient undergoes subsequent chemotherapy, this resistance value can still be used. When the resistance value changes greatly, the patient's blood resistance value can be measured after blood sampling and compared with the resistance value when the PICC tube assembly is connected to the resistance measuring device. If the two are consistent, then the warning value is set again. If the difference between the two is large, it also means that a fibrin sheath has formed on the patient's PICC tube assembly, and the fibrin sheath needs to be dissolved before chemotherapy.

[0036] The resistance measuring device takes into account the measurement of blood resistance. To avoid the influence of high voltage, the voltage input to the metal wire does not exceed 1 volt. In this example, it is 0.5 volt to avoid the influence of large voltage on human cells and cause discomfort. The device body has the function of setting resistance parameters. The blood resistance value in the body can be read in real time through the screen, and the warning value can be set according to the read resistance value by pressing the button. The control board calculates the measured resistance and compares it with the resistance warning value in real time. When it exceeds the warning value range, an alarm is issued. Medical staff perform operations to dissolve the fibrin sheath.

[0037] Working principle: Before PICC intubation, confirm the length of the PICC tube assembly required by the patient, and use the trimming tool to cut off a part of the length of the end of the PICC tube, so that the metal wire at the end will be exposed. After intubation, insert the end of the PICC tube assembly into the 1 / 3 of the superior vena cava, and fix the PICC tube assembly outside the human body. At this time, use a wire to connect the metal wire 1 and metal wire 2 on the PICC tube assembly according to the corresponding color, and connect the other end to the resistance measuring device to complete the construction of the whole system. The fibrin sheath takes a long time to form, so the resistance measuring device of the PICC tube assembly just inserted into the blood vessel can accurately measure the resistance value of the blood and feedback it to the device. Based on the measured blood resistance value, medical staff take into account that the human blood resistance value will have a slight change. Therefore, when setting the warning value, this part of the change needs to be considered, which can be set to ±10% of the measured resistance value. As time goes by, a fibrin sheath may form on the surface of the PICC tube assembly, which will cover the metal wire and cause a significant change in the resistance value measured by the metal wire. Once the set warning value is exceeded, the buzzer alarm sounds, and the medical staff injects heparin through the cavity inside the PICC tube to dissolve the fibrin sheath. If the fibrin sheath is not formed, the resistance value will not exceed the limit, so the buzzer will not alarm. After chemotherapy is completed, the tube sealing liquid is injected to seal the tube. Before the next chemotherapy, the PICC tube assembly and the resistance measuring device are connected with a wire, and the resistance value is compared with the measured resistance value. If there is no change, continue to use it. If the change is large from the last measurement, a part of the patient's blood can be drawn to measure the resistance value and then compared with the resistance of the resistance measuring device. If the two are consistent, reset the warning value and perform chemotherapy. If the difference between the two is large, it means that the PICC tube assembly has formed a fibrin sheath. Inject heparin to dissolve the fibrin sheath. After the resistance values ​​of the two are consistent, it means that the fibrin sheath is completely dissolved. Perform subsequent chemotherapy.

[0038] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A PICC system for preventing fibrin sheath, characterized in that: The invention comprises a PICC tube body (1) and a resistance measuring device (2), wherein the PICC tube body (1) is provided with a resistance detection head (3) for measuring the resistance of blood when the PICC tube body (1) is inserted into the superior vena cava, and the 301 and (3) are connected to the resistance measuring device (2). When the resistance measuring device (2) detects that the resistance of the blood detected by the resistance detection head (3) exceeds the initially set warning value, it indicates that a fibrin sheath is formed outside the PICC tube body (1), and the resistance measuring device (2) issues an alarm message. After receiving the alarm message, the medical staff immediately injects sodium heparin into the PICC tube body (1) to dissolve the fibrin sheath.

2. A PICC system for preventing fibrin sheath according to claim 1, characterized in that: The resistance detection head (3) comprises a first metal wire (301) and a second metal wire (302) buried in a PICC tube body (1); the first metal wire (301) and the second metal wire (302) are arranged along the length direction of the PICC tube body (1); the end faces of the first metal wire (301) and the second metal wire (302) extend out of the end face of the PICC tube body (1); and the first metal wire (301) and the second metal wire (302) are respectively connected to the positive electrode and the negative electrode of the resistance measuring device (2) via a conductor (4); the PICC tube body (1), the first metal wire (301) and the second metal wire (302) constitute a PICC tube assembly.

3. A PICC system for preventing fibrin sheath according to claim 2, characterized in that: The metal wire 1 (301) and the metal wire 2 (302) are both titanium metal wires.

4. A PICC system for preventing fibrin sheath according to claim 2, characterized in that: The resistance measuring device (2) comprises a device housing (201), a control board (201) is arranged in the device housing (201), a main control module (202), a resistance measuring module (203) and a buzzer (204) are arranged on the control board (201), and the input end of the resistance measuring module (203) is respectively connected to a metal wire 1 (301) and a metal wire 2 (302), and the output end of the resistance measuring module (2) is connected to the main control module (202), and the buzzer (204) is connected to the main control module (202).

5. A PICC system for preventing fibrin sheath according to claim 2, characterized in that: The metal wire 1 (301) and the metal wire 2 (302) are provided with color distinguishing marks.

6. A PICC system for preventing fibrin sheath according to any one of claims 1 to 5, characterized in that: The working method of the PICC system is as follows: before inserting the PICC tube assembly, confirm the length of the PICC tube assembly required by the patient, and use a trimming tool to cut off a portion of the length of the PICC tube end, so that the metal wire 1 and the metal wire 2 of the end of the PICC tube assembly are exposed to the end surface of the PICC tube body; after inserting the tube, the end of the PICC tube assembly is inserted into 1 / 3 of the superior vena cava, and the PICC tube assembly left outside the human body is fixed, and at this time, the metal wire 1 and the metal wire 2 on the PICC tube assembly are connected according to the corresponding colors with a wire, and the other end is connected to the electric wire. The resistance measuring device is connected together, and then the PICC tube assembly inserted into the blood vessel is used in conjunction with the resistance measuring device to accurately measure the resistance value of the blood. After a period of time, a fibrin sheath is formed on the surface of the PICC tube assembly, which covers the metal wire, resulting in a significant change in the resistance value measured by the metal wire. Once the set warning value is exceeded, the buzzer alarm sounds, and the medical staff injects heparin through the cavity inside the PICC tube to dissolve the fibrin sheath. If the fibrin sheath is not formed, the resistance value will not exceed the limit, so the buzzer will not alarm; After chemotherapy is completed, sealing liquid is injected to seal the tube. Before the next chemotherapy, the PICC tube assembly and the resistance measuring device are connected with a wire and compared with the measured resistance value. If there is no change, continue to use it. If it changes greatly from the last measured value, a portion of the patient's blood can be drawn to measure the resistance value and then compare it with the resistance of the resistance measuring device. If the two are consistent, reset the warning value and perform chemotherapy. If the two are significantly different, it means that a fibrin sheath has formed in the PICC tube assembly. Inject heparin to dissolve the fibrin sheath. When the resistance values ​​of the two are consistent, it means that the fibrin sheath is completely dissolved. Then proceed with the subsequent chemotherapy process.

7. A PICC system for preventing fibrin sheath according to claim 1, characterized in that: The resistance measuring device calculates the specific resistance of different patients after the PICC tube assembly is inserted into the superior vena cava, and then sets the warning value according to this resistance and records it. When the patient's resistance value exceeds the warning value during chemotherapy, the resistance measuring device will alarm, and then remind the medical staff to inject sodium heparin to dissolve the fibrin sheath. The PICC tube is generally left in the patient's body for up to one year. Therefore, according to the patient's blood resistance value recorded before, when the patient undergoes subsequent chemotherapy, this resistance value can still be used. When the resistance value changes greatly, the patient's blood resistance value can be measured after blood sampling and compared with the resistance value when the PICC tube assembly is connected to the resistance measuring device. If the two are consistent, then the warning value is set again. If the difference between the two is large, it also means that a fibrin sheath has formed on the patient's PICC tube assembly, and the fibrin sheath needs to be dissolved before chemotherapy.

8. A PICC system for preventing fibrin sheath according to claim 1, characterized in that: The voltage inputted by the resistance measuring device (2) to the metal wire 1 (301) and the metal wire 2 (302) does not exceed 1 volt.

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