Tumor electric field treatment system, electrode plate, tumor treatment equipment and method

Abstract

The invention provides a tumor electric field treatment system, an electrode plate, a tumor treatment device and a method, the system comprises at least one pair of electrode plates, each electrode plate comprises a plurality of electrode units and a plurality of temperature detection units, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups, the grounding ends of the temperature detection units in each row group are jointly connected to a grounding pin through a control switch, and the signal ends of the temperature detection units in each column group are jointly connected to a switching unit through a dual-purpose signal line after being in short circuit with the corresponding electrode units; when the dual-purpose signal line is communicated to a temperature sampling point, the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point by configuring the on-off state of the control switch; when the dual-purpose signal line is connected to the alternating power line, an alternating electric signal is applied to the electrode units of at least one column group based on the alternating power line. In this way, a plurality of electrode units can be zoned and controlled using fewer conductive traces.

Description

Technical Field

[0001] The present application relates to tumor electric field therapy technology, and in particular to a tumor electric field therapy system, an electrode sheet, a tumor treatment device and a method. Background Art

[0002] Tumor electric field therapy is a method that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis of cells during mitosis, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatments, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) within cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] The tumor electric field therapy system in the related art uses an electric field application device to transmit the alternating electric signal for tumor electric field therapy to the electrode sheet, and then applies the alternating electric field to the patient's tumor site through the electrode sheet for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the application site, and the temperature will rise accordingly. Therefore, it is necessary to monitor the temperature of the application site. When the temperature is too high, the electric field strength needs to be adjusted in time to reduce the risk of skin burns caused by excessive temperature.

[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which has multiple electrode units. Even if the same alternating electrical signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field therapy, it is necessary to implement individual control on the over-temperature electrode units. However, for the electrode sheets in the related art, the individual control of the electrode units requires a conductive trace to be set for each electrode unit in the substrate of the electrode sheet, which will increase the number of conductive traces in the electrode sheet substrate so that the electrode sheet is not easy to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet. Summary of the invention

[0006] The present application aims to solve at least one of the technical problems in the related art to a certain extent. To this end, the first purpose of the present application is to propose a tumor electric field therapy system, which can control multiple electrode units by partitioning using fewer conductive traces, which can not only improve the effect of tumor electric field therapy, but also facilitate the application of electrode sheets.

[0007] The second objective of the present application is to provide an electrode sheet.

[0008] The third object of this application is to provide another tumor electric field treatment system.

[0009] The fourth objective of the present application is to provide a tumor treatment device.

[0010] The fifth objective of the present application is to provide a method for detecting the temperature of an electrode sheet.

[0011] The sixth objective of the present application is to provide a method for detecting electrode abnormalities.

[0012] The seventh objective of the present application is to provide a control method for a tumor electric field therapy system.

[0013] The eighth objective of the present application is to provide a method for identifying electrode sheet types.

[0014] A ninth objective of the present application is to provide a computer-readable storage medium.

[0015] The tenth objective of the present application is to provide an adapter for tumor electric field therapy.

[0016] The eleventh objective of the present application is to provide an electric field generator for tumor electric field therapy.

[0017] To achieve the above-mentioned purpose, the first aspect of the present application provides a tumor electric field treatment system, comprising: at least one pair of electrode sheets, each of which comprises a plurality of electrode units and a plurality of temperature detection units, each of which can apply an alternating electrical signal, and each of which is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups, and the grounding ends of the temperature detection units in each row group are connected to the grounding pin through a control switch, and the signal ends of the temperature detection units in each column group are respectively short-circuited with the corresponding electrode units and then connected to the switching unit through a dual-purpose signal line; the switching unit is configured to switch the dual-purpose signal line to be connected to a temperature sampling point or an alternating power line, so that when the dual-purpose signal line is connected to the temperature sampling point, the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point by configuring the switch state of the control switch; when the dual-purpose signal line is connected to the alternating power line, the electrode unit of at least one column group is applied with the alternating electrical signal based on the alternating power line.

[0018] According to the tumor electric field therapy system of the embodiment of the present application, for each electrode sheet, multiple electrode units are divided into multiple row groups and multiple column groups, and the ground ends of the temperature detection units corresponding to each electrode unit in each row group are commonly connected to the ground pin through a control switch, and the signal ends of the temperature detection units corresponding to each electrode unit in each column group are respectively short-circuited with the corresponding electrode units and then commonly connected to the switching unit through a dual-purpose signal line; at the same time, the switching unit is configured to switch the dual-purpose signal line to connect to the temperature sampling point or the alternating power line, so that when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point, and when the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one column group are applied with an alternating electrical signal based on the alternating power line. In this way, temperature sampling and application of alternating electric signals can be achieved through the dual-purpose signal line. Not only does no new AC signal line (i.e., AC line) need to be added, but the original AC signal line is also eliminated. Therefore, multiple electrode units can be partitioned and controlled using fewer conductive traces, which not only improves the effect of tumor electric field therapy, but also facilitates the application of electrode sheets.

[0019] Furthermore, the switching unit is also configured to switch the dual-purpose signal line corresponding to each column group to be connected to the corresponding temperature sampling point respectively, so that the analog temperature signal detected by each temperature detection unit in each column group is sampled respectively according to the switching state of the control switch.

[0020] Furthermore, the switching unit is also configured to switch the dual-purpose signal lines corresponding to at least two of the column groups and simultaneously connect them to the corresponding temperature sampling points, so that the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the corresponding temperature sampling points according to the switching state of the configured control switch.

[0021] Furthermore, the switching unit includes at least two bidirectional switches, a first end of each of the bidirectional switches is connected to the dual-purpose signal line corresponding to each of the column groups, a second end of each of the bidirectional switches is simultaneously connected to the alternating power line, and a third end of each of the bidirectional switches is connected to the temperature sampling point of the corresponding column group.

[0022] Furthermore, the switching unit is further configured to switch the dual-purpose signal line corresponding to each column group to be connected to the alternating power line respectively, so that the electrode unit of each column group is simultaneously applied with the alternating electrical signal based on the alternating power line.

[0023] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the column groups to be simultaneously connected to the alternating power line, so that the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0024] Furthermore, the intensity of the alternating electric signal output by the alternating power line is adjustable.

[0025] Furthermore, the switching unit includes at least two bidirectional switches, a first end of each of the bidirectional switches is connected to a dual-purpose signal line corresponding to each of the column groups, a second end of each of the bidirectional switches is connected to a different alternating power line, and a third end of each of the bidirectional switches is connected to a temperature sampling point of the corresponding column group.

[0026] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two column groups to connect to different alternating power lines, so that each electrode unit of each column group is applied with the alternating electrical signal based on different alternating power lines.

[0027] Furthermore, the strength of the alternating electrical signals output by different alternating power lines can be adjusted respectively.

[0028] Furthermore, each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

[0029] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0030] Furthermore, an adapter is included, wherein the control switch, the switching unit and the voltage-dividing resistor are respectively arranged in the adapter.

[0031] Furthermore, the adapter includes a first controller and an ADC unit, the ADC unit is connected to each of the temperature sampling points to sample the analog temperature signal through each of the temperature sampling points, and the first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

[0032] Furthermore, the first controller is also configured to configure the switch state of the control switch.

[0033] Furthermore, the first controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0034] Furthermore, it also includes an electric field generator, which is configured to output the alternating electric signal through the alternating power line.

[0035] Furthermore, the electric field generator includes a second controller and an AC signal generator, the second controller is connected to the AC signal generator, and the second controller is configured to control the AC signal generator to adjust the strength of the alternating electric signal output by the alternating power line.

[0036] Furthermore, the electric field generator is also configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

[0037] Furthermore, the electric field generator also includes a power switch, which is arranged between the AC signal generator and the switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

[0038] Furthermore, the second controller is also configured to configure the switch state of the control switch.

[0039] Furthermore, the second controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0040] To achieve the above-mentioned purpose, the second aspect of the present application provides an electrode sheet for use in a tumor electric field therapy system, the tumor electric field therapy system comprising a switching unit, the electrode sheet comprising: a substrate; a plurality of electrode units and a plurality of temperature detection units arranged on the substrate, each of the electrode units being capable of applying an alternating electrical signal, each of the temperature detection units being arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups; the ground terminals of the temperature detection units in each of the row groups are connected to a ground pin via a control switch; each of the column groups After the signal ends of the temperature detection units are short-circuited with the corresponding electrode units respectively, they are connected to the switching unit through a dual-purpose signal line, so that the dual-purpose signal line is switched to the temperature sampling point or the alternating power line through the switching unit; when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, the electrode unit of at least one column group is applied with the alternating electrical signal based on the alternating power line.

[0041] Furthermore, when the dual-purpose signal lines corresponding to each column group are respectively connected to corresponding temperature sampling points, the analog temperature signals detected by each temperature detection unit in each column group are respectively sampled by configuring the switch state of the control switch.

[0042] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to corresponding temperature sampling points, the switching state of the control switch is configured so that the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the corresponding temperature sampling points.

[0043] Further, in the case that the dual-purpose signal lines corresponding to each of the column groups are respectively connected to the alternating power lines, the electrode units of each of the column groups are simultaneously applied with the alternating electrical signals based on the alternating power lines.

[0044] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the alternating power line, the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0045] Furthermore, the intensity of the alternating electric signal output by the alternating power line is adjustable.

[0046] Further, in the case that the dual-purpose signal lines corresponding to the at least two column groups are connected to different alternating power lines, the alternating electrical signals are applied to the electrode units of each column group based on different alternating power lines.

[0047] Furthermore, the strength of the alternating electrical signals output by different alternating power lines can be adjusted respectively.

[0048] Furthermore, each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

[0049] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0050] Furthermore, each of the electrode units is provided with a through hole, and the through hole is suitable for accommodating the temperature detection unit.

[0051] Furthermore, the plurality of electrode units and the plurality of temperature detection units are arranged roughly in an array in terms of spatial arrangement, and the plurality of electrode units and the plurality of temperature detection units are arranged in multiple rows and columns in terms of circuit connection.

[0052] Furthermore, the number of the plurality of electrode units and the number of the plurality of temperature detection units are both 20, and they are arranged in groups of four rows and five columns in terms of circuit connection.

[0053] To achieve the above-mentioned purpose, the third aspect of the present application provides a tumor electric field treatment system, comprising: at least one pair of the aforementioned electrode sheets; an electric field generator, the electric field generator is used to generate an alternating power supply and transmit the alternating power supply to each of the electrode sheets through the alternating power supply line; a control unit, the control unit is used to configure at least one of the switching state of the control switch and the switching state of the switching unit, so as to sample the analog temperature signal detected by the corresponding temperature detection unit in each of the row groups based on the corresponding temperature sampling point, or control at least one of the electrode units of the column group to be applied with the alternating electric signal based on the alternating power supply line.

[0054] To achieve the above-mentioned purpose, the fourth aspect of the present application provides a tumor treatment device, including: the aforementioned tumor electric field treatment system.

[0055] To achieve the above-mentioned purpose, the fifth aspect of the present application provides an electrode sheet temperature detection method, which is applied to the aforementioned tumor electric field therapy system or to the aforementioned tumor electric field therapy system, and the method includes: controlling the switching unit so that the dual-purpose signal line corresponding to at least one of the column groups in the corresponding electrode sheet is connected to the corresponding temperature sampling point; controlling the control switch corresponding to each of the row groups so as to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0056] Furthermore, when the dual-purpose signal lines corresponding to each of the column groups are respectively connected to the corresponding temperature sampling points, the control switches corresponding to each of the row groups are controlled, including: controlling the control switches corresponding to each of the row groups to close in sequence to respectively sample the analog temperature signals of each electrode unit in each of the column groups.

[0057] Furthermore, when the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to corresponding temperature sampling points, the control switches corresponding to each of the row groups are controlled, including: controlling the control switches corresponding to each of the row groups to close in sequence to respectively sample the analog temperature signals of the corresponding electrode units in each of the row groups.

[0058] To achieve the above-mentioned purpose, the sixth aspect of the present application provides an electrode sheet abnormality detection method, wherein a preset threshold is preset in the adapter or the electric field generator, and the method comprises: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and judging whether the electrode sheet has an abnormality based on the temperature detection signal.

[0059] Further, judging whether the electrode sheet is abnormal according to the temperature detection signal includes: when it is determined according to the temperature detection signal that any electrode unit in the corresponding electrode sheet is abnormal or fails, judging that the electrode sheet is unqualified.

[0060] Furthermore, judging whether the electrode sheet is abnormal is based on the temperature detection signal, including: when it is determined that there are abnormal or faulty electrode units in the corresponding electrode sheet based on the temperature detection signal, determining the number of abnormal or faulty electrode units; when the number of abnormal or faulty electrode units reaches a preset threshold, determining that the electrode sheet needs to be replaced.

[0061] Furthermore, judging whether the electrode sheet is abnormal according to the temperature detection signal includes: comparing the temperature of each electrode unit in the corresponding electrode sheet with a preset temperature threshold according to the temperature detection signal; and judging whether the temperature of the electrode sheet is abnormal according to the comparison result.

[0062] Further, judging whether the temperature of the electrode sheet is abnormal according to the comparison result includes: when the temperature at any electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, determining that the temperature of the electrode sheet is abnormal.

[0063] To achieve the above-mentioned purpose, the seventh aspect of the present application provides a control method for a tumor electric field therapy system, wherein a preset temperature threshold, a preset quantity threshold, a first preset temperature and a second preset temperature are preset in the adapter or the electric field generator, and the method comprises: determining the temperature detection signal of each electrode unit in each of the electrode sheets by executing the aforementioned electrode sheet temperature detection method; and controlling the intensity of the alternating electric signal applied to the electrode unit according to the temperature detection signal.

[0064] Furthermore, the strength of the alternating electric signal applied to the electrode unit is controlled according to the temperature detection signal, including: comparing the temperature at each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; and controlling the strength of the alternating electric signal according to the comparison result.

[0065] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature of at least one electrode unit exceeds a preset temperature threshold, stopping applying the alternating electric signal to the electrode unit of the electrode sheet.

[0066] Furthermore, stopping applying the alternating electric signal to the electrode units of the electrode sheet includes: stopping applying the alternating electric signal to all electrode units of the electrode sheet; or stopping applying the alternating electric signal to all electrode units in the column group where the electrode units in the electrode sheet that exceed a preset temperature threshold are located.

[0067] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature at at least one electrode unit exceeds a preset temperature threshold, determining the number of over-temperature column groups; when the number of over-temperature column groups exceeds a preset number threshold, stopping applying the alternating electric signal to all electrode units of the electrode sheet; when the number of over-temperature column groups does not exceed the preset number threshold, stopping applying the alternating electric signal to all electrode units in the column group where the electrode unit exceeding the preset temperature threshold is located in the electrode sheet.

[0068] Furthermore, when the application of the alternating electric signal to all electrode units in the column group where the electrode unit exceeding the preset temperature threshold in the electrode sheet is located is stopped, the method further includes: continuing to apply the alternating electric signal to the electrode units in other column groups in the electrode sheet.

[0069] Furthermore, the intensity of the alternating electric signal applied to the electrode units of other column groups in the electrode sheet is adjustable.

[0070] Furthermore, the intensity of the alternating electric signal applied to the electrode units of each column group in the other column groups is adjustable.

[0071] Furthermore, the strength of the alternating electric signal is controlled according to the comparison result, including: when the temperatures at all electrode units in the electrode sheet do not exceed a preset temperature threshold, if the temperatures at all electrode units in the electrode sheet do not exceed a first preset temperature, increasing the strength of the alternating electric signal applied to the electrode units of the electrode sheet, wherein the first preset temperature is less than the preset temperature threshold.

[0072] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: if the temperature at at least one electrode unit in the electrode sheet exceeds the first preset temperature and is less than the preset temperature threshold, then the strength of the alternating electric signal currently applied to the electrode unit of the electrode sheet remains unchanged.

[0073] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: if the temperature at at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than the preset temperature threshold, reducing the intensity of the alternating electric signal applied to the electrode unit of the electrode sheet, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0074] Furthermore, when the number of over-temperature column groups does not exceed a preset number threshold, the method also includes: if the temperature at each electrode unit in the non-over-temperature column group does not exceed a first preset temperature, increasing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0075] Furthermore, when the number of over-temperature column groups does not exceed a preset number threshold, the method also includes: if the temperature of at least one electrode unit in the non-over-temperature column group exceeds a first preset temperature and is less than a preset temperature threshold, then the strength of the alternating electric signal currently applied to the electrode unit of the non-over-temperature column group is maintained unchanged.

[0076] Furthermore, when the number of over-temperature column groups does not exceed a preset number threshold, the method also includes: if the temperature of at least one electrode unit in the non-over-temperature column group exceeds a second preset temperature and is less than a preset temperature threshold, reducing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature column group, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0077] Furthermore, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase range.

[0078] Furthermore, the increasing ranges of the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased are different from each other.

[0079] Furthermore, maintaining the strength of the alternating electric signal currently applied to the electrode unit unchanged includes: maintaining the strength of the alternating electric signal currently applied to the first target column group unchanged, wherein the first target column group is a column group where the temperature at the electrode unit exceeds the first preset temperature and is less than a preset temperature threshold.

[0080] Further, reducing the strength of the alternating electric signal applied to the electrode unit includes: reducing the strength of the alternating electric signal applied to the electrode unit of the second target column group, wherein the second target column group is a column group where the temperature of the electrode unit exceeds the second preset temperature and is less than the preset temperature threshold.

[0081] To achieve the above-mentioned purpose, the eighth aspect of the present application provides an electrode sheet type identification method, the method comprising: determining the temperature detection signal of each electrode unit in each of the electrode sheets by executing the aforementioned electrode sheet temperature detection method; and identifying the type of the electrode sheet according to the temperature detection signal.

[0082] To achieve the above-mentioned purpose, the ninth aspect of the present application provides a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0083] To achieve the above-mentioned objectives, the tenth embodiment of the present application provides an adapter for tumor electric field therapy, including a first memory and a first controller, wherein the first memory stores a computer program, and when the computer program is executed by the first controller, the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method is implemented.

[0084] To achieve the above-mentioned purpose, the eleventh embodiment of the present application provides an electric field generator for tumor electric field therapy, including a second memory and a second controller, the second memory storing a computer program, and when the computer program is executed by the second controller, the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method is implemented.

[0085] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0086] Figure 1 A schematic diagram of a tumor electric field treatment system according to an embodiment of the present application;

[0087] Figure 2 for Figure 1 The schematic diagram of the structure of the electrode sheet of the tumor electric field treatment system shown;

[0088] Figure 3 for Figure 1 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown;

[0089] Figure 4 and Figure 3 Similar to Figure 3 A schematic diagram of another circuit connection between an electrode sheet and an adapter is shown;

[0090] Figure 5 for Figure 1 The schematic diagram of the circuit connection between an electrode sheet, an adapter and an electric field generator of the tumor electric field treatment system shown;

[0091] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system shown;

[0092] Figure 7 for Figure 1 A schematic block diagram of the internal structure of an electric field generator of a tumor electric field treatment system is shown;

[0093] Figure 8 A schematic diagram of a flow chart of an electrode sheet temperature detection method according to an embodiment of the present application;

[0094] Fig. 9 A schematic diagram of a flow chart of an electrode sheet abnormality detection method according to an embodiment of the present application;

[0095] Fig.10 A schematic flow chart of a control method of a tumor electric field treatment system according to an embodiment of the present application;

[0096] Fig.11 A schematic diagram of a flow chart of an electrode sheet type identification method according to an embodiment of the present application;

[0097] Fig.12 A schematic flow chart of a signal control method for tumor electric field therapy according to an embodiment of the present application;

[0098] Fig.13 A schematic flow chart of an electrode sheet temperature detection method according to another embodiment of the present application;

[0099] Fig.14 A schematic flow chart of a method for applying an alternating electric signal for electric field therapy of tumors according to another embodiment of the present application;

[0100] Fig.15 It is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to an embodiment of the present application;

[0101] Fig.16 It is a flowchart of a method for applying an alternating electric signal based on a temperature detection signal according to another embodiment of the present application.

[0102] Fig.17 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0103] Fig.18 A schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of a tumor electric field treatment system according to another embodiment of the present application;

[0104] Fig.19 for Fig.18 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system shown;

[0105] Fig. 20 for Fig.18 A schematic block diagram of the internal structure of an electric field generator of a tumor electric field treatment system is shown;

[0106] Fig.21 A schematic flow chart of a control method of a tumor electric field treatment system according to another embodiment of the present application;

[0107] Fig. 22 A schematic flow chart of a signal control method for tumor electric field therapy according to another embodiment of the present application;

[0108] Description of reference numerals:

[0109] Tumor electric field treatment system 100 or 100', electrode sheet 13 or 13', first cable 15 or 15', adapter 20 or 20', second cable 25 or 25', electric field generator 30 or 30', substrate 31 or 31', electrode unit 33 or 33', temperature detection unit 35 or 35', ground terminal 35-1 or 35-1', signal terminal 35-2 or 35-2', temperature sensor 34 or 34', ground terminal 34-1 or 34-1', signal terminal 34-2 or 34-2', electrode unit 33 or 33', diode 36 or 36', Anode 36-1 or 36-1', cathode 36-2 or 36-2', second power supply module 32 or 32', second controller 37 or 37', second communication unit 38 or 38', AC signal generator 39 or 39', power switch 40 or 40', first controller 51 or 51', ADC unit 52 or 52', voltage divider resistor 53 or 53', control switch 54 or 54', first control switch 54-1 or 54-1', second control switch 54-2 or 54-2', third control switch 54-3 or 54-3', fourth control switch 54- 4 or 54-4', a two-way switch 55 or 55', a first two-way switch 55-1 or 55-1', a second two-way switch 55-2 or 55-2', a third two-way switch 55-3 or 55-3', a fourth two-way switch 55-4 or 55-4', a fifth two-way switch 55-5 or 55-5', a first communication unit 56 or 56', an alternating power line 57 or 57', a first power module 58 or 58', a grounding line 18 or 18', a first grounding line 18-1 or 18-1', and a second grounding line 18-2 or 18-2' , the third ground line 18-3 or 18-3', the fourth ground line 18-4 or 18-4', the dual-purpose signal line 19 or 19', the first dual-purpose signal line 19-1 or 19-1', the second dual-purpose signal line 19-2 or 19-2', the third dual-purpose signal line 19-3 or 19-3', the fourth dual-purpose signal line 19-4 or 19-4', the fifth dual-purpose signal line 19-5 or 19-5', the first connector 60 or 60', the first plug 61, the first socket 62, the second connector 70 or 70', the second plug 71 or 71', the second socket 72 or 72'. DETAILED DESCRIPTION

[0110] The following embodiments of the technical solution of the present application are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.

[0111] Embodiment 1:

[0112] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field treatment system 100 includes: at least one pair of electrode sheets 13, an adapter 20 connected to the at least one pair of electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode sheets 13 can be arranged in pairs on the patient's body surface, such as Figure 1 There are four electrode sheets 13, and every two electrode sheets 13 are arranged as a pair on the patient's body surface. The electric field generator 30 is used to supply power to at least one pair of electrode sheets 13, so that at least one pair of electrode sheets 13 generates an alternating electric field for treating tumors. The adapter 20 is electrically connected between at least one pair of electrode sheets 13 and the electric field generator 30, and is used to transmit the alternating electric signal generated by the electric field generator 30 to at least one pair of electrode sheets 13. In other words, the electric field generator 30 is capable of generating an alternating electric signal, and the alternating electric signal generated by the electric field generator 30 is transmitted to each electrode sheet 13 through the adapter 20, so that an alternating electric field for treating tumors is generated between the same pair of electrode sheets 13, so as to apply an alternating electric field to the tumor site of the patient for tumor treatment.

[0113] like Figure 1 As shown, in this embodiment, the number of electrode sheets 13 is 4, each electrode sheet 13 includes a plurality of electrode units 33 of the same number, each electrode unit 33 is electrically connected to the adapter 20, and the number of electrode units 33 on each electrode sheet 13 is 20. In other embodiments, the tumor electric field treatment system 100 may also have more or fewer electrode sheets 13; in other embodiments, each pair of electrode sheets 13 has the same number of electrode units 33, and different pairs of electrode sheets 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode sheet 13 may be 9, 13, etc.

[0114] Figure 3 and Figure 4 for Figure 1 The circuit connection diagram of the electrode sheet 13 and the adapter 20 in two working states of the tumor electric field treatment system 100 is shown. It is worth noting that: Figure 3 and Figure 4 The arrangement of the electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. Figure 3 and Figure 4 The arrangement of the electrode units 33 shown does not represent the arrangement of the electrode units 33 in the spatial structure. Figure 1 , Figure 3 as well as Figure 4The electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 35, and a first cable 15 electrically connected to the substrate 31. The substrate 31 may be a flexible circuit board. The substrate 31 is embedded with a plurality of conductive traces, which include a plurality of grounding wires 18 and a plurality of dual-purpose signal wires 19. The first cable 15 has a plurality of core conductors (not shown), each of which is electrically connected to the plurality of grounding wires 18 and the plurality of dual-purpose signal wires 19 of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of grounding wires 18 and dual-purpose signal wires 19 embedded in the substrate 31 does not exceed 10, and thus the number of conductors of the first cable 15 does not exceed 10.

[0115] The plurality of electrode units 33 are configured into a plurality of row groups and a plurality of column groups. In the present embodiment, each electrode sheet 13 is provided with 20 electrode units 33, and the 20 electrode units 33 are arranged in the order of 1 to 20 in the circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode unit 33 and the temperature detection unit 35 are both welded on the substrate 31, and the electrode unit 33 is short-circuited with the signal terminal 35-2 of the corresponding temperature detection unit 35. Since the plurality of temperature detection units 35 are arranged one by one with the plurality of electrode units 33, the plurality of temperature detection units 35 are also arranged in four row groups and five column groups in the circuit connection. It should be noted that the arrangement here is to more clearly show the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure. Figure 2The structure shown as an array may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The electrode unit 33 is configured to apply an alternating electric field to the patient's tumor site. The temperature detection unit 35 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 13, that is, the temperature at the corresponding electrode unit 33, and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the substrate 31 are respectively arranged in a one-to-one correspondence with the multiple column groups of the electrode units 33, and are configured to transmit the alternating electric signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding column group. That is, the electrode units 33 in the same column group are short-circuited by the same dual-purpose signal line 19 of the substrate 31, and the electrode units 33 in different column groups are respectively connected in parallel by different dual-purpose signal lines 19 of the substrate 31. The dual-purpose signal line 19 of the substrate 31 is electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electric signal generated by the electric field generator 30 through the first cable 15 and the adapter 20 .

[0116] Each electrode unit 33 of the electrode sheet 13 has three modes of working state. In the first mode, the electrode unit 33 applies an alternating current signal through the dielectric element 35; in the second mode, the temperature sensor 34 detects or collects the temperature of the patient's body surface to which the corresponding electrode unit 33 is attached; in the third mode, the application of the alternating current signal and the temperature detection and collection are stopped. The first mode, the second mode, and the third mode do not overlap each other in time period. That is, the time period in which the dielectric element 35 of the electrode unit 33 applies the alternating current signal is staggered and does not overlap with the time period in which the temperature sensor 34 detects the temperature. The electrode unit 33 can switch cyclically between applying an alternating current signal through its dielectric element 35 and detecting the temperature through its temperature sensor 34, that is, the electrode unit 33 can switch cyclically between the first mode and the second mode. The electrode unit 33 can also switch cyclically between the first mode, the second mode, and the third mode, that is, the electrode unit 33 switches cyclically between applying an alternating current signal through the dielectric element 35, collecting or detecting the temperature through the temperature sensor 34, and stopping applying the alternating current signal and collecting the temperature.

[0117] The multiple grounding wires 18 are respectively arranged in one-to-one correspondence with the multiple row groups of the electrode units 33, and the multiple grounding wires 18 are respectively used to short-circuit each temperature detection unit 35 corresponding to each row group to ground. That is, the grounding ends 35-1 of the multiple temperature detection units 35 in the same row group are short-circuited through the same grounding wire 18 of the substrate 31, and the grounding ends 35-1 of the temperature detection units 35 in different row groups are respectively connected in parallel through different grounding wires 18 of the substrate 31. During the time period of temperature detection, only one of the multiple grounding wires 18 is turned on at the same time, and the other three are turned off.

[0118] Each of the multiplexed dual-purpose signal lines 19 is also configured to short-connect the signal end 35-2 of at most one temperature detection unit 35 in each row group to an external device for receiving detection signals, wherein the signal end 35-2 of the temperature detection unit 35 connected to each of the multiplexed dual-purpose signal lines 19 is different from each other, so as to avoid the dual-purpose signal line 19 from subsequently outputting duplicate signals. That is, when the number of electrode units 33 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal end 35-2 of a different temperature detection unit 35 in the row group; when the number of electrode units 33 in a row group is less than the number of dual-purpose signal lines 19, there is at least one dual-purpose signal line 19 that is not electrically connected to the signal end 35-2 of the temperature detection unit 35, and each of the remaining dual-purpose signal lines 19 is electrically connected to the signal end 35-2 of a different temperature detection unit 35 in the row group. In this embodiment, the external device for receiving detection signals is an adapter 20. The signal ends 35 - 2 of the temperature detection units 35 in different column groups are connected in parallel through different dual-purpose signal lines 19 of the substrate 31 , and the signal ends 35 - 2 of the temperature detection units 35 in the same column group are short-circuited to the same dual-purpose signal line 19 of the substrate 31 .

[0119] In this embodiment, when each electrode unit 33 is equipped with a temperature detection unit 35 for temperature detection, the above-mentioned circuit design is used to reduce the number of wires of the first cable 15, avoid the cable becoming thicker, the cable becoming harder and increasing the difficulty of cable fixing; at the same time, avoid the increase in the number of wires of the first cable 15 affecting the adhesion effect between the electrode sheet 13 and the corresponding body surface of the patient's tumor site. The grounding wire 18 and the dual-purpose signal wire 19 embedded in the substrate 31 are 9 lines in total. Specifically, in this embodiment, the grounding wire 18 embedded in the substrate 31 is 4 lines, and the dual-purpose signal wire 19 is 5 lines. The number of grounding wires 18 is related to the number of row groups M of the electrode unit 33, which is greater than or equal to the number of row groups of the electrode unit 33, and M is a positive integer. The number of dual-purpose signal wires 19 is related to the number of column groups N of the electrode unit 33, which is greater than or equal to the number of column groups of the electrode unit 33, and N is a positive integer. The line L embedded in the substrate 31 of the electrode sheet 13 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal wires 19. In this embodiment, the number of grounding lines 18 is equal to the number M of row groups of electrode units 33 ; the number of dual-purpose signal lines 19 is equal to the number N of column groups of electrode units 33 .

[0120] The plurality of electrode units 33 are arranged on the substrate 31 in a two-dimensional array. Figure 2 As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33 and 20 temperature detection units 35 corresponding to the electrode units 33. The 20 electrode units 33 are arranged in an array of four rows and six columns. The first row and the fourth row each have four electrode units 33, and the second row and the third row each have six electrode units 33. The four electrode units 33 in each of the first row and the fourth row are located in each of the second to fifth columns, and the six electrode units 33 in each of the second and third rows are located in each of the first to sixth columns. The four electrode units 33 located in the first row are divided into region 1, the electrode units 33 located in the first column of the second row, the first column of the third row, and the second and third columns of the fourth row are divided into region 2, the electrode units 33 located in the sixth column of the second row, the sixth column of the third row, and the fourth and fifth columns of the fourth row are divided into region 3, the electrode units 33 located in the second and third columns of the second row, and the second and third columns of the third row are divided into region 4, and the electrode units 33 located in the fourth and fifth columns of the second row and the fourth and fifth columns of the third row are divided into region 5. Each region (1-5) corresponds to a column group respectively. In some other embodiments, the 20 electrode units 33 can also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 13 can also have other numbers of electrode units 33. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0121] Each electrode unit 33 can apply an alternating electric signal, and the electrode sheets 13 configured in pairs are used to apply an alternating electric field to the patient's tumor site. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer composed of a polymer material. Each temperature detection unit 35 is arranged corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be arranged at any position of the corresponding electrode unit 33. In this embodiment, each electrode unit 33 is provided with a perforation 331, and the perforation 331 is suitable for installing the temperature detection unit 35. For example, the middle part of each electrode unit 33 has a perforation 331 arranged therethrough, and each perforation 331 of the electrode unit 33 accommodates a corresponding temperature detection unit 35. Each temperature detection unit 35 includes a temperature sensor 34 and a diode 36. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1. The diode 36 has an anode 36-1 and a cathode 36-2. The anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34. The cathode 36-2 of the diode 36 serves as the ground terminal 35-1 of the temperature detection unit 35. The signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensors other than thermistors. Each temperature sensor 34 corresponds to a diode 36. The diode 36 is connected in series with the temperature sensor 34 of the same electrode unit 33, which can prevent the reverse flow of current to prevent the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0122] like Figure 3 or Figure 4As shown, the electrode sheet 13 of this embodiment includes 4 grounding wires 18, and each grounding wire 18 is used to ground the grounding ends 35-1 of the temperature detection units 35 in the same row group. The 4 grounding wires 18 of the electrode sheet 13 are respectively the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3 and the fourth grounding wire 18-4. Among the 4 row groups of the electrode sheet 13, the first row group is the electrode unit 33-1 to the electrode unit 33-5, the second row group is the electrode unit 33-6 to the electrode unit 33-10, the third row group is the electrode unit 33-11 to the electrode unit 33-15, and the fourth row group is the electrode unit 33-16 to the electrode unit 33-20. Specifically, the first grounding wire 18-1 is used to ground the electrode units 33-1 to 33-5 in the first row group; the second grounding wire 18-2 is used to ground the electrode units 33-6 to 33-10 in the second row group; the third grounding wire 18-3 is used to ground the electrode units 33-11 to 33-15 in the third row group; the fourth grounding wire 18-4 is used to ground the electrode units 33-16 to 33-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or disconnected, which can be achieved by connecting each grounding wire 18 in series with a control switch 54, that is, the grounding terminal 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 in each row group is connected to the ground pin through a control switch 54, which will be described in detail below. The above-mentioned “grounding the electrode unit 33” may refer to grounding the grounding terminal 34-1 of the temperature sensor 34 corresponding to each electrode unit 33, or may refer to connecting the diode 36 in series with the temperature sensor 34 corresponding to the same electrode unit 33 and grounding them together. In short, each grounding line 18 short-circuits the grounding terminals 35-1 of the temperature detection units 35 corresponding to all the electrode units 33 in each row group and grounds them.

[0123] like Figure 3 or Figure 4As shown, the electrode sheet 13 of this embodiment also includes 5 dual-purpose signal lines 19, one end of each dual-purpose signal line 19 is respectively connected to all electrode units 33 in each column group, and the other end thereof is connected to the adapter 20 for receiving temperature detection signals and transmitting alternating electrical signals. That is, for each row group, each dual-purpose signal line 19 can choose to connect to one of the electrode units 33 or not connect to any electrode unit 33 in the row group to avoid the dual-purpose signal line 19 from subsequently outputting duplicate signals. Specifically, the 5 dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the four electrode units 33, namely, electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16, and the signal end 35-2 of the temperature detection unit 35 corresponding to each of them; one end of the second dual-purpose signal line 19-2 is connected to the four electrode units 33, namely, electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17, and the signal end 35-2 of the temperature detection unit 35 corresponding to each of them; one end of the third dual-purpose signal line 19-3 is connected to the electrode unit 33-3, electrode unit 33-8, and electrode unit 33 The fourth dual-purpose signal line 19-4 is connected to the four electrode units 33 of electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, electrode unit 33-19 and the signal end 35-2 of the temperature detection unit 35 respectively; the fifth dual-purpose signal line 19-5 is connected to the four electrode units 33 of electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, electrode unit 33-20 and the signal end 35-2 of the temperature detection unit 35 respectively. In short, each dual-purpose signal line 19 short-circuits the electrode units 33 in the same column group and the signal end 35-2 of the temperature detection unit 35 respectively and is used to connect to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals, which can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 55 and coordinating the closing or opening of the ground line 18.That is to say, after the signal ends 35-2 of each temperature detection unit 35 in each column group are short-circuited with the corresponding electrode unit 35 respectively, they are connected to a switching unit (unnumbered) through a dual-purpose signal line 19. The switching unit (unnumbered) includes a plurality of bidirectional switching switches 55, which are configured to switch the dual-purpose signal line 19 to connect to a temperature sampling point (unnumbered) or an alternating power line 57, so that when the dual-purpose signal line 19 is connected to the temperature sampling point (unnumbered), the switching state of the control switch 54 is configured to make the temperature detection signal detected by the corresponding temperature detection unit 35 in each row group be sampled based on the temperature sampling point (unnumbered), and when the dual-purpose signal line 19 is connected to the alternating power line 57, an alternating electrical signal is applied to the electrode unit 33 of at least one column group based on the alternating power line 57, which will be described in detail below.

[0124] The multiple grounding wires 18 and the multiplexed signal wires 19 are conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multiple grounding wires 18 and the multiplexed signal wires 19 embedded in the substrate 31 are electrically connected to corresponding wires (not shown) in the first cable 15 one by one.

[0125] The tumor electric field treatment system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 13, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides an alternating electric signal to a plurality of electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or is used to receive the temperature detection signal output by the temperature detection unit 35 corresponding to the plurality of electrode units 33. The adapter 20 transmits the alternating electric signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13, and is also configured to receive the temperature detection signal output by the multiplex dual-purpose signal line 19 of the electrode sheet 13.

[0126] refer to Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 51, multiple groups of ADC units 52 connected to the first controller 51, multiple groups of piezoelectric resistors 53 and multiple groups of control switches 54 corresponding to the multiple groups of ADC units 52, multiple groups of bidirectional switching switches 55 corresponding to the multiple groups of ADC units 52, a first communication unit 56, an alternating power line 57 corresponding to each group of bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51 and the multiple groups of ADC units 52, and the first power module 58 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered), which are electrically connected to the multiple ground lines 18 and the multiple dual-purpose signal lines 19 in the substrate 31 of the electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (not labeled) include multiple alternating power lines 57 that transmit alternating electrical signals to the corresponding electrode sheets 13 and are electrically connected to the multiplexed signal lines 19 in the substrate 31 of the corresponding electrode sheets 13, multiple circuit lines (not labeled) that are electrically connected one-to-one with the multiplexed signal lines 19 in the substrate 31 of the corresponding electrode sheets 13 and are used to supply power to each temperature detection unit 35 of the electrode sheet 13 or transmit the temperature detection signal of the electrode sheet 13, and multiple circuit lines (not labeled) that are electrically connected one-to-one with the multiple grounding lines 18 in the substrate 31 of the corresponding electrode sheets 13. The number L of circuit lines electrically connected between the adapter 20 and one electrode sheet 13 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode sheet 13; the number H of circuit lines electrically connected between the adapter 20 and X electrode sheets 13 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13, that is, H=XL=X*(M+N). The number of groups of the control switches 54 and the number of groups of the bidirectional switching switches 55 are both related to the number of electrode sheets 13. The number of groups of the control switches 54 is the same as the number of groups of the bidirectional switching switches 55, and is not less than the number of electrode sheets 13. Optionally, the number of groups of the control switches 54 and the number of groups of the bidirectional switching switches 55 are both the same as the number of electrode sheets 13. The following is a detailed description of the electrical connection between an electrode sheet 13 having 20 electrode units 33 and an adapter 20 as an example.

[0127] Each group of control switches 54 is provided with a plurality of control switches 54, which are respectively connected to the adapter 20 and are respectively electrically connected to circuit lines (not numbered) corresponding to the multi-way grounding lines 18 of a corresponding electrode sheet 13, and are configured to control the conduction or disconnection of the multi-way grounding lines 18. The circuit lines (not numbered) of the multi-way grounding lines 18 electrically connected to the electrode sheets 13 are grounded at one end close to the control switches 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding lines 18 of the substrate 31 of the corresponding electrode sheet 13, and the two are equal in this embodiment. Figure 3 or Figure 4 As shown, in this embodiment, the multiple control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3 and a fourth control switch 54-4. The multiple control switches 54 in the same group control the closing or disconnection of the corresponding grounding wire 18 of the same electrode sheet 13 one by one. The first control switch 54-1 is used to control the closing or disconnection of the first grounding wire 18-1 of the corresponding electrode sheet 13, and then cooperates with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 in the first row group 33 of the electrode sheet 13; the second control switch 54-2 is used to control the closing or disconnection of the second grounding wire 18-2 of the electrode sheet 13, and then cooperates with the corresponding group of two-way switching switches 55 to control the power on and off of the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 in the second row group 33 of the electrode sheet 13; The third control switch 54-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 in the third row group 33 of the electrode sheet 13; the fourth control switch 54-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 in the fourth row group 33 of the electrode sheet 13. The above-mentioned control switch 54 can be a mechanical switch, such as a relay. The control switch 54 can also be an electronic switch, and each control switch 54 can be opened and closed by an additional first controller 51.

[0128] In this embodiment, the multiple groups of control switches 54 are all electronic switches. The first controller 51 is connected to the multiple groups of control switches 54 for sequentially and cyclically controlling the on and off states of multiple control switches 54 in each group of control switches 54, and then sequentially and individually conducting each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and cooperating with the switching of the corresponding two-way switching switch 55 to collect the temperature of the patient's body surface detected by all the temperature detection units 35 on the electrode sheet 13. The number of each group of control switches 54 is not less than the number of grounding wires 18 of the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of each group of control switches 54 is the same as the number of grounding wires 18 of the corresponding electrode sheet 13.

[0129] Each set of two-way switches 55 is provided with a plurality of two-way switches 55, and the plurality of two-way switches 55 in each set are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19 of the corresponding electrode sheet 13. The number of two-way switches 55 in each set of two-way switches 55 is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, which is greater than or equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, and in this embodiment, the two are equal. Each bidirectional switching switch 55 has a signal acquisition terminal 1 marked as 1 and a signal input terminal 2 marked as 2. The signal acquisition terminals 1 of multiple bidirectional switching switches 55 in the same group are electrically connected one by one to corresponding detection channels of multiple detection channels of a corresponding group of ADC units 52 through temperature sampling points (unnumbered), and the signal input terminals 2 of each bidirectional switching switch 55 in the same group are electrically connected to the corresponding same alternating power line 57, and are configured to control the multi-channel dual-purpose signal line 19 to connect to the corresponding alternating power line 57 to transmit alternating electrical signals or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0130] like Figure 3 or Figure 4As shown, taking an electrode sheet 13 electrically connected to the adapter 20 as an example, in this embodiment with 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3, a fourth bidirectional switch 55-4 and a fifth bidirectional switch 55-5. The plurality of bidirectional switches 55 in the same group respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of a corresponding one of the multiplexed dual-purpose signal lines 19 of the same electrode sheet 13. Specifically, the first bidirectional switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 in the first column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 in the first column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the first column of electrode units 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 transmit the alternating electric signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. signal; the second bidirectional switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the second column electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 transmit the alternating electric signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52;The third bidirectional switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 in the third column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit corresponding to the electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 in the third column group and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the third column electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18 transmit the alternating electric signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the corresponding ADC unit 52; The fourth bidirectional switch 55-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 in the fourth column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 in the fourth column group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the fourth column electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19 transmit the alternating electric signal to the patient or output the temperature detection signal collected by the temperature detection unit 35 corresponding to these electrode units 33 to the ADC unit 52;The fifth bidirectional switching switch 55-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode sheet 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the conduction of each electrode unit 33 of the electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 in the fifth column group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 in the fifth column group and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, and control switch 54-4, so that the fifth column electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20 transmit alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. When the signal input terminal 2 of each set of two-way switching switches 55 is turned on and the signal collection terminal 1 is turned off, an alternating electrical signal can be transmitted to each electrode unit 33 of the corresponding electrode sheet 13. When the signal collection terminal 1 of each set of two-way switching switches 55 is turned on and the signal input terminal 2 is turned off, it can cooperate with each control switch 54 in the corresponding set of control switches 54 to transmit the temperature detection signal collected by the temperature detection unit 35 of each electrode element 33 on the electrode sheet 13 in a time-sharing manner. The above-mentioned two-way switching switch 55 can be a mechanical switch, such as a relay. The two-way switching switch 55 can also be an electronic switch, and each two-way switching switch 55 can be switched by an additional first controller 51. ;

[0131] In this embodiment, the plurality of groups of two-way switches 55 are all electronic switches. The first controller 51 is in communication connection with the plurality of groups of two-way switches 55, and is used to control the plurality of two-way switches 55 in each group of two-way switches 55 to switch between their respective signal acquisition terminals 1 and signal input terminals 2, and to coordinate the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35 on the electrode sheet 13 or transmit an alternating electrical signal to the patient.

[0132] In this embodiment, each group of ADC units 52 is electrically connected to the signal acquisition terminals 1 of the plurality of bidirectional switching switches 55 in the corresponding group of bidirectional switching switches 55 through the multi-channel circuit lines (not numbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital signal. Each group of ADC units 52 includes a plurality of detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 through the corresponding bidirectional switching switch 55. Figure 3 or Figure 4 As shown, each group of ADC units 52 includes 5 detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through the signal acquisition terminal 1 of the first two-way switch 55-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through the signal acquisition terminal 1 of the second two-way switch 55-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through the signal acquisition terminal 1 of the third two-way switch 55-3, the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the signal acquisition terminal 1 of the fourth two-way switch 55-4, and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through the signal acquisition terminal 1 of the fifth two-way switch 55-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature detection unit 35 corresponding to the electrode unit 33 to which the corresponding dual-purpose signal line 19 is connected. In addition, each detection channel A, B, C, D, E is connected to a first power module 58 for providing a detection voltage to the detection channel A, B, C, D, E via a corresponding voltage divider resistor 53 in the adapter 20, and the first power module 58 provides direct current.

[0133] In this embodiment, the first communication unit 56 is configured to obtain the digital signals output by the multiple groups of ADC units 52 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital signal. Exemplarily, when any of the multiple digital signals received exceeds the preset threshold, it means that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds the preset temperature threshold (for example, 41°C, 42°C, etc.), and the voltage of the alternating electric signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 33 of the electrode sheet 13 from being too high in temperature when the alternating electric signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset temperature threshold and preset threshold can be determined according to the human safety threshold. The first communication unit 56 is controlled by the first controller 51 and transmits the digital signals converted by the multiple groups of ADC units 52 in series. In this embodiment, the preset temperature threshold can be a value within 36°C-45°C.

[0134] refer to Figure 5 and Figure 6In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30, and is configured to supply power to the first controller 51, the multiple ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is connected between each electrode sheet 13 and the adapter 20, and the first connector 60 is suitable for connecting the corresponding electrode sheet 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 provided at an end of the first cable 15 away from the electrode sheet 13 and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are push-type spring connectors, that is, the first connector 60 uses a connector to connect the adapter 20 with the electrode sheet 13. Each first cable 15 has 5 wires electrically connected to the two-way switch 55 in the corresponding group of two-way switches 55 and 4 wires electrically connected to the control switch 54 in the corresponding group of control switches 54, that is, each first connector 60 is electrically connected to a corresponding group of two-way switch 55 and a corresponding group of control switch 54 of the adapter 20 through 9 wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0135] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is suitable for connecting the electric field generator 30 to the adapter 20. Figure 1As shown, the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 provided at an end of the second cable 25 away from the first controller 51 and a second socket 72 provided on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, that is, the second connector 70 uses a connector to connect the adapter 20 to the electric field generator 30. Each first connector 60 such as X1, Y1, X2 and Y2 is connected to the second connector 70 through a corresponding alternating power line 57, and the first connector 60 such as X1, Y1, X2 and Y2 is also connected to a corresponding group of control switches 54 and a corresponding group of ADC units 52, wherein each first connector 60 is connected to the second connector 70 and a corresponding group of ADC units 52 through a corresponding group of bidirectional switching switches 55. The second cable 25 has 8 conductors, including 4 conductors 1 to 4 electrically connected to the corresponding alternating power lines 57 and used to transmit alternating electrical signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data sending line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 through the data receiving line RX and the data sending line TX, the VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded, and the VCC pin of the second connector 70 is also connected to the corresponding group of voltage dividers 53 and the corresponding group of ADC units 52 through the VCC power line of the first power module 58.

[0136] refer to Figure 5 and Figure 7The electric field generator 30 includes: a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38 and a group of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to the second controller 37 and the AC signal generator 39 respectively and supplies power to them. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and is electrically connected to the wire 6 of the second connector 70 through its data sending line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39 and a group of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the group of power switches 40 and adjust the relevant parameters of the alternating electric signal applied by the AC signal generator 39 according to the relevant digital signal received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the wires 1 to 4 of the second connector 70 for transmitting the alternating electric signal through the group of power switches 40. The group of power switches 40 includes a plurality of power switches 40, and the plurality of power switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each power switch 40 is electrically connected to a corresponding wire 1, 2, 3, 4 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, 41-2, 41-3, 41-4 and is electrically connected to the corresponding electrode sheet 13 through the corresponding wires 1, 2, 3, 4 of the second connector 70, so as to transmit the alternating electric signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the group of power switches 40 through a plurality of AC power lines 41. Specifically, the number of power switches 40 of the electric field generator 30 is related to the number of electrode sheets 13. In this embodiment, the number of power switches 40 is equal to the number of electrode sheets 13 and both are 4. The power switches 40 include a first power switch 40-1, a second power switch 40-2, a third power switch 40-3, and a fourth power switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 in a one-to-one correspondence.One end of the first power switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting the alternating electric signal in the second connection 70 through an AC power line 41-1, and is electrically connected to the alternating power line 57 at the port X1 of the adapter 20 through the wire 1 of the second connector 70, the alternating power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20 One end of the second power switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-2, and is electrically connected to the alternating power line 57 of the adapter 20 at the port Y1 through the wire 2 of the second connector 70, the alternating power line 57 of the adapter 20 at the port Y1 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20 One end of the third power switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-3, and is electrically connected to the alternating power line 57 of the adapter 20 at the port X2 through the wire 3 of the second connector 70, the alternating power line 57 of the adapter 20 at the port X2 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20 One end of the fourth power switch 40-4 is electrically connected to the AC signal generator 39 through the AC power line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting alternating electric signals in the second connection 70 through an AC power line 41-4 and is electrically connected to the alternating power line 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the alternating power line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0137] The following will refer to Figures 3 to 5 The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.

[0138] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal collection end 1 of each of the multiple bidirectional switching switches 55 of a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal input end 2 to be turned off, so as to disconnect the alternating electric signal applied to the electrode sheet 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the control switches 54 of a group of control switches 54 electrically connected to the electrode sheet 13 to be turned on in sequence in a time-sharing manner. At this time, the temperature detection signals collected by each temperature detection unit 35 corresponding to each electrode unit 33 of each row group of the electrode sheet 13 can be collected in a time-sharing manner in a sequence through multiple detection channels A, B, C, D, and E of a group of ADC units 52 corresponding to the electrode sheet 13. Each detection channel A, B, C, D, E of each group of ADC units 52 only collects the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13 in the same row group at the same time, and the above temperature detection signal can be represented by a voltage value. Among the four control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13, only one control switch 54 can be turned on at the same time, and the other three are turned off. The five bidirectional switching switches 55 of a group of bidirectional switching switches 55 corresponding to the group of ADC units 52 are all switched to their respective signal acquisition terminals 1 so that each dual-purpose signal line 19 of the electrode sheet 13 is electrically connected to the corresponding detection channel A, B, C, D, E of the corresponding ADC unit 52 in a one-to-one correspondence and turned on. With such a setting, the group of ADC units 52 can collect the voltage values ​​of all temperature detection units 35 corresponding to each electrode unit 33 in the same row group that is short-circuited with a ground line 18 corresponding to the turned-on control switch 54.

[0139] Specifically, when the control switch 54-1 is closed, the control switches 54-2, 54-3 and 54-4 are all opened, and the first two-way switch 55-1, the second two-way switch 55-2, the third two-way switch 55-3, the fourth two-way switch 55-4 and the fifth two-way switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-1 to 33-5 of the first row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-6 to 33-20 of the remaining row groups are powered off, and the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, 33-11 and 33-16 of the first detection channel A in the group of ADC units 52 are short-circuited. The signal end 35-2 of the detection unit 35, since only the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is connected to the ground, and the ground ends 35-1 of the temperature detection units 35 corresponding to the electrode units 33-6, 33-11, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-1 is effectively operated on the first detection channel A of the group of ADC units 52, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Similarly, the voltage value collected on the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-2. The voltage value collected on the third detection channel C in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-3. The voltage value collected on the fourth detection channel D in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-4. The voltage value collected on the fifth detection channel E in the ADC unit 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-5.

[0140] When the control switch 54-2 is closed, the control switches 54-1, 54-3 and 54-4 are all opened, and the first two-way switch 55-1, the second two-way switch 55-2, the third two-way switch 55-3, the fourth two-way switch 55-4 and the fifth two-way switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-6 to 33-10 of the second row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-5 and the electrode units 33-11 to 33-20 of the remaining row groups are powered off, and the electrode units 33-1, 33-6, 33-11 and 33-16 on the first detection channel A in the group of ADC units 52 are short-circuited. The signal end 35-2 of each corresponding temperature detection unit 35, because only the ground end 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is connected to the ground, and the ground end 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-1, the electrode unit 33-11, and the electrode unit 33-16 is disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-6. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-6 is effectively operated on the first detection channel A of the group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6. Similarly, the voltage value collected on the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-7. The voltage value collected on the third detection channel C in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-8. The voltage value collected on the fourth detection channel D in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-9. The voltage value collected on the fifth detection channel E in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-10.

[0141] When the control switch 54-3 is closed, the control switches 54-1, 54-2 and 54-4 are all opened, and the first two-way switch 55-1, the second two-way switch 55-2, the third two-way switch 55-3, the fourth two-way switch 55-4 and the fifth two-way switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-11 to 33-15 of the third row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-10 and the electrode units 33-16 to 33-20 of the remaining row groups are powered off, and the electrode units 33-1, 33-6, 33-11 and 33-16 on the first detection channel A in the group of ADC units 52 are short-circuited. From the signal end 35-2 of the corresponding temperature detection unit 35, since only the ground end 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-11 is connected to the ground, and the ground ends 35-1 of the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, and 33-16 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, it will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-11. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-11 is effectively operated on the first detection channel A of the group of ADC units 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-11. Similarly, the voltage value collected on the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-12. The voltage value collected on the third detection channel C in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-13. The voltage value collected on the fourth detection channel D in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-14. The voltage value collected on the fifth detection channel E in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-15.

[0142] When the control switch 54-4 is closed, the control switches 54-1, 54-2 and 54-3 are all opened, and the first two-way switch 55-1, the second two-way switch 55-2, the third two-way switch 55-3, the fourth two-way switch 55-4 and the fifth two-way switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature detection units 35 corresponding to the electrode units 33-16 to 33-20 of the fourth row group are powered on, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-15 of the remaining row groups are powered off, and the temperature detection units 35 corresponding to the electrode units 33-1 to 33-15 of the first detection channel A of the ADC unit 52 of the group are short-circuited. 5, since only the grounding terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-16 is connected to the ground, and the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, and 33-11 are disconnected, and each temperature detection unit 35 includes a temperature sensor 34 and a diode 36 connected in series with the temperature sensor 34, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-16. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-16 on the first detection channel A of the group of ADC units 52 is effectively running. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-16. Similarly, the voltage value collected on the second detection channel B in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-17. The voltage value collected on the third detection channel C in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-18. The voltage value collected on the fourth detection channel D in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-19. The voltage value collected on the fifth detection channel E in the group of ADC units 52 is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-20.

[0143] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of a certain electrode sheet 13 by controlling a group of bidirectional switching switches 55 and a group of control switches 54 that are electrically connected to the electrode sheet 13. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be connected to the corresponding temperature sampling points (unnumbered) at the same time, and by configuring the switch states of the corresponding control switches 54, the temperature detection signals detected by the corresponding temperature detection units 35 in each row group are sampled based on the corresponding temperature sampling points (unnumbered). Similarly, the temperature detection signals of the temperature detection units 35 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0144] The first controller 51 or the second controller 37, the multiple groups of ADC units 52 and the multiple groups of bidirectional switches 55 can automatically perform operations through pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls all the bidirectional switches 55 in the corresponding group of bidirectional switches 55 to switch to the signal acquisition end 1 so that the signal acquisition ends 1 of the bidirectional switches 55 are all turned on and the signal input ends 2 are all turned off so that the dual-purpose signal lines 19 of the corresponding electrode sheets 13 are electrically connected to the corresponding group of ADC units 52, and then closes the control switch 54-1 in the corresponding group of control switches 54, and disconnects the remaining control switches 54-2 to 54-4 in the group of control switches 54. During this period, the group Each detection channel A, B, C, D, E of the ADC unit 52 obtains the temperature detection signal of each temperature detection unit 35 corresponding to each electrode unit 33 located in the first row group in the corresponding electrode sheet 13 and converts it into a digital signal and stores it in a separately set memory. Then, after a preset interval, the first controller 51 or the second controller 37 closes the control switch 54-2 in the group of control switches 54 and disconnects the control switch 54-1, the control switch 54-3 and the control switch 54-4 in the group of control switches 54. During this period, each detection channel A, B, C, D, E of the ADC unit 52 obtains the temperature detection signal of each temperature detection unit 35 corresponding to each electrode unit 33 located in the second row group. In this way, each control switch 54 in the group of control switches 54 is turned on separately in turn, and the temperature detection signal of all the temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, the temperature detection signal of all the temperature detection units 35 on at least one pair of electrode sheets 13 is obtained through this operation.

[0145] It should be noted that, in other embodiments, a group of bidirectional switching switches 55 and a group of control switches 54 electrically connected to a certain electrode sheet 13 can also be controlled by the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 to realize the collection of temperature detection signals of the temperature detection units 35 corresponding to some electrode units 33 of the electrode sheet 13 in the same temperature collection time period. For example, when only the first bidirectional switching switch 55-1 is switched to its signal collection terminal 1, the switch 54-1 can be controlled to be closed first, and the control switches 54-2, 54-3 and 54-4 can be disconnected. At this time, only the temperature detection unit 35 corresponding to the electrode unit 33-1 of the first row group is energized, and the signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the group of ADC units 52. Therefore, the group of ADC units 52 will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1; then, the control switch 54-2 is controlled to be closed, and the control switches 54-1, 54-3 and 54-4 are controlled to be closed. 3 and control switch 54-4 are all disconnected, at this time, the group of ADC units 52 will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6; then control the control switch 54-3 to be closed, control switch 54-1, control switch 54-2 and control switch 54-4 are all disconnected, at this time, the group of ADC units 52 will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-11; finally, control switch 54-4 is closed, control switch 54-1, control switch 54-2 and control switch 54-3 are all disconnected, at this time, the group of ADC units 52 will detect the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-16. Therefore, in the same acquisition time period, only the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 of one column group can be sampled. Similarly, in other acquisition time periods, the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 of other column groups can be sampled. That is, the switching unit (not labeled) is configured to switch the dual-purpose signal line 19 corresponding to each column group to be connected to the corresponding temperature sampling point (not labeled), and the temperature detection signal detected by each temperature detection unit 35 in each column group is sampled respectively by configuring the switch state of the control switch 54. It should be noted that in other embodiments, the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 of two column groups, three column groups or four column groups can also be sampled within the same sampling time period, which will not be described in detail here.

[0146] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input end 2 of each of the multiple bidirectional switching switches 55 of a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal acquisition end 1 to be turned off, and controls a power supply switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to be connected to the alternating power line 57 at the same time, so that the electrode units 33 of at least two column groups are simultaneously applied with alternating electric signals based on the alternating power line 57.

[0147] It should be noted that, in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switches 55 electrically connected to a certain electrode sheet 13 to apply an alternating electric signal to some electrode units 33 of the electrode sheet 13 in the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal input terminal 2 of the first bidirectional switch 55-1 among the multiple bidirectional switches 55 of the group of bidirectional switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal acquisition terminal 1 to be turned off, and controls a power switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to the first column group electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16 of the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal line 19 corresponding to each column group to be connected to the alternating power line 57, so that the electrode units 33 of each column group are simultaneously applied with an alternating electrical signal based on the alternating power line 57. It should be noted that in other embodiments, the alternating electrical signal can also be simultaneously applied to the electrode units 33 of two column groups, three column groups, or four column groups in the same time period, which will not be described in detail here.

[0148] It should be noted that the control switch 54 electrically connected to the multi-way grounding wires 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to the multi-way dual-purpose signal wires 19 of the electrode sheet 13 in the embodiment of the present application are both provided in the adapter 20, but in other embodiments, the control switch 54 electrically connected to the grounding wire 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal wire 19 can also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the ADC unit 52 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0149] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35 obtained; or if the electrode sheet is qualified, identify the type of the electrode sheet based on the obtained temperature detection signal; or if the electrode sheet is qualified, determine whether the electrode unit 33 of the electrode sheet 13 is over-temperature based on the obtained temperature detection signal, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode units 33 of the corresponding column of the electrode sheet 13, so as to avoid low-temperature burns on the patient's body surface when the tumor is treated through the electrode sheet 13. In addition, the substrate 31 of the electrode sheet 13 of the present application is electrically connected to the same electrode unit 33 and the signal end 35-2 of the corresponding temperature detection unit 35 through the same dual-purpose signal line 19. While it can transmit both alternating electrical signals and direct current signals for temperature signal collection and collected temperature detection signals through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the substrate 31, simplifies the manufacturing process, reduces the weight of the substrate 31, and reduces the manufacturing cost. The electrode sheet 13 of the present application can also switch between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature collection and transmitting collected temperature detection signals through the combined control of the control switch 54 electrically connected to the grounding line 18 arranged thereon and the bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0150] Specifically, when it is necessary to apply an alternating electric signal to the patient through the electrode units 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls to disconnect all the control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13, and at the same time controls to switch all the bidirectional switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to their respective signal input terminals 2, so that the signal acquisition terminals 1 of the bidirectional switching switches 55 are all disconnected and the signal input terminals 2 are all turned on, so that all the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to an alternating power line 57 corresponding to the adapter 20 and the electrode sheet 13, thereby transmitting the alternating electric signal to each electrode unit 33 of the electrode sheet 13.When the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through an alternating power line 57 corresponding to the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; when the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20 When the electric field generator 30 reduces the voltage or current of the alternating electric signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage or current of the alternating electric signal applied to the pair of electrode sheets 13; when it is detected that the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the electric field generator 30 controls the power switch 40 electrically connected to the electrode sheet 13 to be disconnected through the second controller 37 to stop applying the alternating electric signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls all the two-way switching switches 55 in a group of two-way switching switches 55 electrically connected to the electrode sheet 13 All of them are switched from their signal input terminal 2 to the signal collection terminal 1, that is, all the signal collection terminals 1 of a group of two-way switching switches 55 electrically connected to the electrode sheet 13 are controlled to be turned on and all the signal input terminals 2 are turned off, thereby stopping the application of the alternating electric signal to the electrode sheet 13; or, when it is detected that the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than the preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls a two-way switching switch electrically connected to the electrode unit 33 of the electrode sheet 13 55 switches from its signal input terminal 2 to its signal acquisition terminal 1, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 simultaneously controls the remaining bidirectional switching switches 55 electrically connected to the electrode units 33 whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold and are in different columns from the electrode units 33 whose temperature detection signals exceed the preset temperature threshold to continue to maintain electrical connection with their respective signal input terminals 2, so as to stop applying alternating electric signals to all electrode units 33 in the column where the electrode units 33 whose temperature detection signals of the electrode sheet 13 exceed the preset temperature threshold are located, and continue to apply alternating electric signals to the electrode units 33 in the remaining columns whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold.Thus, the method for controlling the application of the alternating electric signal based on the temperature detection signal of the tumor electric field therapy system 100 is realized.

[0151] The present application embodiment provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet 13 or tumor electric field treatment system 100, referring to Figure 8 As shown, it includes the following steps:

[0152] Step 210: Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0153] Specifically, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 and simultaneously connect the direct current signal applied to the signal end 35-2 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13.

[0154] Further, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch from one end electrically connected to the alternating electric signal to one end electrically connected to the direct electric signal, that is, the bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch from its signal input end 2 to its signal acquisition end 1; or, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch the electrode unit 33 of each electrode unit 33 of the electrode sheet 13 from the on state to the off state, and at the same time, the signal end 35-2 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 is switched from the off state to the on state.

[0155] Step 220: Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0156] Specifically, the control switch 54 electrically connected to the ground terminal 35 - 1 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 is turned on in a time-sequential manner to obtain the temperature detection signal of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 .

[0157] In some embodiments, when the dual-purpose signal lines 19 corresponding to each column group are respectively connected to the corresponding temperature sampling points, the control switches 54 corresponding to each row group are controlled, including: controlling the control switches 54 corresponding to each row group to close in sequence to respectively sample the analog temperature signals of each electrode unit 33 in each column group.

[0158] In other embodiments, when the dual-purpose signal lines 19 corresponding to at least two column groups are simultaneously connected to the corresponding temperature sampling points, the control switch 54 corresponding to each row group is controlled, including: controlling the control switch 54 corresponding to each row group to close in sequence to respectively sample the analog temperature signals of the corresponding electrode units 33 in each row group.

[0159] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperatures of all electrode units of the electrode sheet; and based on the temperature detection signals of all the temperature detection units of the electrode sheet, it can be judged whether the temperature detection units of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified or needs to be replaced; it is also possible to judge whether each electrode unit of the electrode sheet is over-temperature based on the temperature detection signals of all the temperature detection units of the electrode sheet when each temperature detection unit of the electrode sheet is normal, and then control the alternating electric signal applied to the electrode sheet or to each electrode unit of the electrode sheet; it is also possible to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature detection unit of the electrode sheet.

[0160] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature, and the second preset temperature is lower than the preset temperature threshold.

[0161] Reference Fig. 9 As shown, the present application also provides a method for detecting abnormal temperature of an electrode sheet, which comprises the following steps:

[0162] Step 210: Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0163] Step 220 : Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0164] Step 230: Determine whether the electrode sheet 13 is abnormal according to the temperature detection signal.

[0165] In some embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0166] Step 231: Compare the temperature of each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold according to the temperature detection signal. Specifically, the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0167] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison result. Specifically, determine whether the temperature of each electrode unit 33 in the electrode sheet 13 is abnormal based on the comparison result.

[0168] The comparison result in step 232 includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C-42°C. Optionally, the preset temperature threshold is 40.5°C-41.5°C. Optionally, the preset temperature threshold is 41°C-41.5°C. Optionally, the preset temperature threshold is 41°C.

[0169] The process of judging whether the temperature of the electrode sheet 13 is abnormal according to the comparison result in step 232 is specifically as follows: when the temperature of any electrode unit 33 in the corresponding electrode sheet 13 exceeds the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. When the temperature of all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0170] In some other embodiments, judging whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0171] Step 233: When it is determined according to the temperature detection signal that any one of the electrode units 33 in the corresponding electrode sheet 13 is abnormal or fails, the electrode sheet 13 is determined to be unqualified.

[0172] Specifically, it is determined whether the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13; and then it is determined whether the electrode sheet 13 is qualified according to whether the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails. When the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails, the electrode sheet 13 is determined to be unqualified; when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is not abnormal or fails, the electrode sheet 13 is determined to be qualified.

[0173] In some other embodiments, judging whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0174] Step 234: when it is determined according to the temperature detection signal that there are abnormal or faulty electrode units 33 in the corresponding electrode sheet 13, the number of the abnormal or faulty electrode units 33 is determined.

[0175] Step 235: When the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0176] Specifically, based on the temperature detection signals obtained from the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13; then, based on whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0177] For example, when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or faulty and the number of the abnormal or faulty temperature detection units 35 exceeds the preset threshold, it is determined that the electrode sheet 13 needs to be replaced; when the number of the temperature detection units 35 that are abnormal or faulty in the electrode sheet 13 does not exceed the preset threshold, it is determined that the electrode sheet 13 does not need to be replaced. The preset threshold is 20% of the total number of all temperature detection units 35 of the electrode sheet 13.

[0178] Reference Fig.10 As shown, the present application also provides a control method for a tumor electric field treatment system, which comprises the following steps:

[0179] Step 210: Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0180] Step 220 : Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0181] Step 240: Control the intensity of the alternating electric signal applied to the electrode unit 33 according to the temperature detection signal.

[0182] Specifically, when it is determined that the electrode sheet 13 does not need to be replaced, the alternating electric signal applied to each electrode unit 33 in the electrode sheet 13 is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13. In other words, steps 234-235 can be added between step 240 and step 220.

[0183] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal in step 240 specifically includes the following steps:

[0184] Step 241: Compare the temperature of each electrode unit 33 in the electrode sheet 13 with a preset temperature threshold according to the temperature detection signal.

[0185] Step 242: Control the strength of the alternating electric signal according to the comparison result.

[0186] In some embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0187] Step 2421: When the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, stop applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13. Specifically, when there is a temperature detection signal exceeding the preset temperature threshold among the temperature detection signals of all the electrode units 33 of the electrode sheet 13 obtained, stop applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13. When the temperature detection signals of each electrode unit 33 in the electrode sheet 13 obtained do not exceed the preset temperature threshold, continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13.

[0188] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13 in step 2421 specifically includes: stopping applying the alternating electric signal to all electrode units 33 of the electrode sheet 13; or stopping applying the alternating electric signal to all electrode units 33 in the column group where the electrode units 33 in the electrode sheet 13 that exceed a preset temperature threshold are located.

[0189] Furthermore, when the application of the alternating electric signal to all the electrode units 33 in the column group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located is stopped, the alternating electric signal continues to be applied to the electrode units 33 in other column groups in the electrode sheet 13. The intensity of the alternating electric signal applied to the electrode units 33 in other column groups in the electrode sheet 13 is adjustable. For example, all the electrode units 33 in the electrode sheet 13 whose temperature detection signal does not exceed the preset temperature threshold and are in different columns from the electrode unit 33 whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the signal is adjustable.

[0190] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0191] Step 2422: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0192] In step 2422, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0193] Step 2423: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if there is at least one electrode unit 33 in the electrode sheet 13 whose temperature exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal currently applied to the electrode unit 33 of the electrode sheet 13 is maintained unchanged.

[0194] Step 2424: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the electrode sheet 13 is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0195] In step 2424, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are reduced have the same reduction amplitude.

[0196] Exemplarily, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature detection signal is close to the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0197] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0198] Step 2425: When the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature column groups.

[0199] Step 2426 : When the number of over-temperature column groups exceeds a preset number threshold, stop applying the alternating electrical signal to all electrode units 33 of the electrode sheet 13 .

[0200] Step 2427: when the number of over-temperature column groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 in the column group where the electrode units 33 exceeding the preset temperature threshold in the electrode sheet 13 are located.

[0201] Furthermore, when the application of the alternating electric signal to all the electrode units 33 in the column group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located is stopped, the alternating electric signal continues to be applied to the electrode units 33 in other column groups in the electrode sheet 13. The intensity of the alternating electric signal applied to the electrode units 33 in other column groups in the electrode sheet 13 is adjustable.

[0202] Step 2428: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature at each electrode unit 33 in the non-over-temperature column group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0203] In step 2428, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0204] Step 2429: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature column group exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal currently applied to the electrode unit 33 of the non-over-temperature column group remains unchanged.

[0205] Step 2430: When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature column group exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature column group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0206] In step 2430, the electric field strengths corresponding to the column groups whose alternating electric signal strengths are reduced have the same reduction amplitude.

[0207] Exemplarily, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature detection signal is close to the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0208] Reference Fig.11 As shown, the present application also provides an electrode sheet type identification method, which comprises the following steps:

[0209] Step 210: Control the switching unit so that the dual-purpose signal line 19 corresponding to at least one column group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point.

[0210] Step 220 : Control the control switch 54 corresponding to each row group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0211] Step 250: Identify the type of the electrode sheet 13 according to the temperature detection signal.

[0212] Specifically, when the electrode sheet 13 is qualified or each temperature detection unit 35 of the electrode sheet 13 has no abnormality or failure, the type of the electrode sheet 13 is identified based on the temperature detection signal detected by the temperature detection unit 35 of each electrode unit 33 in the electrode sheet 13.

[0213] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13, and the method includes: combining and controlling a control switch 54 and a bidirectional switching switch 55 electrically connected to the electrode sheet 13 so that each electrode unit 33 of the electrode sheet 13 switches between applying an alternating electric signal and collecting a temperature detection signal.

[0214] Reference Fig.12 As shown, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 13, and the method includes:

[0215] Step 310: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and executing step 320;

[0216] Step 320: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect the temperature detection signals of the electrode units 33 of the electrode sheet 13 in a row and executing step 330;

[0217] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signal and execute step 340;

[0218] Step 340 : Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the control switch 54 and the bidirectional switch 55 .

[0219] The working state of each electrode unit 33 of the electrode sheet 13 in step 340 includes at least one of: stopping applying the alternating electric signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating electric signal. Continuing to apply the alternating electric signal includes continuing to apply the alternating electric signal in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged, or continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal.

[0220] The working state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal collected by it. Each electrode unit 33 of the electrode sheet 13 is divided into different areas, and each electrode unit 33 in each area can be cyclically switched between applying an alternating electric signal and collecting a temperature detection signal through the combination of a control switch 54 and a bidirectional switch 55.

[0221] The present application embodiment provides another electrode temperature detection method for the tumor electric field treatment system 100, please refer to Fig.13 As shown, the temperature detection method includes:

[0222] Step 510: disconnect the input of the alternating electric signal of the electrode sheet 13, perform combination control on the multiple control switches 54 and the multiple bidirectional switching switches 55, and obtain the temperature detection signal of the temperature sensor 34 of the electrode sheet 13 corresponding to each combination in all the combinations;

[0223] Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 34 in the electrode sheet 13 to obtain a digital temperature signal;

[0224] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field treatment system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signal.

[0225] In step 510, the combined control of the plurality of control switches 54 and the plurality of bidirectional switching switches 55 specifically includes:

[0226] Step 511: placing all the bidirectional switches 55 at the signal acquisition terminal 1 to conduct the electrical connection between the signal terminals 35 - 2 of the temperature detection units 35 corresponding to all the electrode units 33 and the corresponding ADC units 52 ;

[0227] Step 512: Sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner, so as to collect the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the corresponding row group row by row.

[0228] In step 512, sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner can turn on the detection channel electrically connected between the ADC unit 52 and each temperature detection unit 35 in the row group corresponding to the closed control switch 54 .

[0229] Thus, the temperature detection signals of the corresponding temperature detection units 35 in each row group can be obtained in turn, and then after processing by the adapter 20 or the electric field generator 30, the corresponding temperatures of all the electrode units 33 on the electrode sheet 13 can be obtained, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0230] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 33 can also be detected as needed. The specific process of the method for temperature detection of a certain electrode unit 33 of the electrode sheet 13 is as follows: disconnect the input of the alternating electric signal, place the two-way switch 55 corresponding to the column group where the electrode unit 33 that needs to be individually measured is located at the signal acquisition terminal 1, and place the remaining two-way switch 55 at the signal input terminal 2; at the same time, turn on and ground the control switch 54 corresponding to the row group where the electrode unit 33 that needs to be individually measured is located, and disconnect all the remaining control switches 54. In this way, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33. For example, the electrode unit 33 that needs to be individually measured is the electrode unit 33-1. At this time, the bidirectional switch 55-1 corresponding to the electrode unit 33-1 is placed at the signal acquisition terminal 1, and the remaining bidirectional switches (55-2 to 55-5) are all placed at the signal input terminal 2; at the same time, the control switch 18-1 corresponding to the electrode unit 33-1 is closed and grounded, and the remaining control switches (18-2 to 18-4) are all disconnected. In this way, the temperature of the electrode unit 33-1 can be detected.

[0231] The present application also provides another method for applying an alternating electric signal for tumor electric field therapy, which is applied to the above tumor electric field therapy system 100. Please refer to Fig.14 As shown, the alternating electric signal applying method includes:

[0232] Step 610: determining the area (1-5) where the electrode unit 33 to which the alternating electric signal needs to be applied in the electrode sheet 13 is located;

[0233] Step 611: Combining and controlling a plurality of control switches 54 and a plurality of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to apply an alternating electrical signal.

[0234] In step 611, the combination of controlling the multiple control switches 54 and the multiple bidirectional switching switches 55 electrically connected to the electrode sheet 13 is specifically as follows:

[0235] Step 612: disconnect all control switches 54 electrically connected to the electrode sheet 13;

[0236] Step 613: determining the column groups where the electrode units 33 in the regions where the alternating electric signals need to be applied are located according to the regions where the electrode units 33 to which the alternating electric signals need to be applied are located;

[0237] Step 614: determining the bidirectional switches 55 electrically connected to the electrode units 33 in the column groups according to the column groups where the electrode units 33 to which the alternating electrical signals need to be applied are located;

[0238] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be applied so that the electrode unit 33 to which the alternating electric signal needs to be applied is electrically connected to the alternating power line 57 to apply the alternating electric signal; at the same time, control the remaining bidirectional switching switches 55 so that the electrical connection between each electrode unit 33 in the area where the alternating electric signal does not need to be applied and the alternating power line 57 is disconnected to stop applying the alternating electric signal.

[0239] In step 615, "the electrode units to which alternating electric signals need to be applied are electrically connected to the alternating power line 57 to apply the alternating electric signals and the electrode units 33 in the areas where the alternating electric signals do not need to be applied are electrically disconnected from the alternating power line 57 to stop applying the alternating electric signals" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the column groups corresponding to the areas (1-5) to which the alternating electric signals are to be applied in the electrode sheet 13 at their signal input terminals 2, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining column groups at the signal acquisition terminal 1.

[0240] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0241] The present application also provides a method for applying an alternating electric signal based on a temperature detection signal, which is used in the above-mentioned tumor electric field treatment system 100. Fig.15 As shown, the application method includes:

[0242] Step 710: Start the tumor therapeutic field system 100;

[0243] Step 711: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0244] Step 712: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0245] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, and execute step 714 when there is no electrode unit 33 whose temperature exceeds the first preset temperature t1; and execute step 715 when there is an electrode unit 33 whose temperature exceeds the first preset temperature t1;

[0246] Step 714: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0247] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 716; when there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 717;

[0248] Step 716: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 712;

[0249] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719;

[0250] Step 718: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0251] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0252] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 721 when the number of over-temperature areas exceeds the preset number threshold; and execute step 724 when the number of over-temperature areas does not exceed the preset number threshold.

[0253] Step 721: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 722;

[0254] Step 722: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and executing step 723;

[0255] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. When the electrode sheet 13 does not have an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 711. When the electrode sheet 13 has an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 722.

[0256] Step 724: distinguishing an over-temperature area from a non-over-temperature area according to whether there is an electrode unit 33 whose temperature exceeds a preset temperature threshold t0, and executing step 725 when the area is an over-temperature area, and executing step 726 when the area is a non-over-temperature area;

[0257] Step 725: stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 731;

[0258] Step 726: Determine whether the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1, execute step 727. When the temperature of each electrode unit 33 in the non-over-temperature area exceeds the first preset temperature t1, execute step 728.

[0259] Step 727: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and execute step 731;

[0260] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0261] Step 729: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and execute step 731;

[0262] Step 730: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 731;

[0263] Step 731: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to reacquire the temperature of each electrode unit 33 of the electrode sheet 13 and select to execute step 732 or step 734, wherein the temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area;

[0264] Step 732: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. When the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0265] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0266] Step 734: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 735. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the first preset temperature t1, execute step 736.

[0267] Step 735: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0268] Step 736: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 737. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the second preset temperature t2, execute step 738.

[0269] Step 737: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 712;

[0270] Step 738: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 739. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 719.

[0271] Step 739 : Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712 .

[0272] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0273] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that applies an alternating electrical signal to each electrode unit 33; or

[0274] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0275] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0276] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 712, step 722, and step 731 is specifically as follows:

[0277] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected, and sequentially close the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 in time division to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0278] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal collection terminals 1, and sequentially close the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in time division to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0279] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and closing the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0280] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electrical signal to transmitting a direct current signal or a temperature detection signal, and the control switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0281] The first preset temperature in step 713, step 723, step 726, step 732, and step 734 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 715, step 728, and step 736 is 40.4°C to 40.6°C, preferably 40.5°C; the preset temperature threshold in step 717 and step 738 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 720 is preferably 2.

[0282] The process of continuing to apply the alternating electric signal in step 714, step 716, step 718, step 727, step 729, step 730, step 735, step 737, and step 739 is specifically as follows:

[0283] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0284] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0285] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input ends 2 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0286] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that their respective signal input terminals 2 are closed and the signal collection terminal 1 is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0287] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0288] Increasing the voltage or current amplitude of the currently applied alternating electric signal in step 714, step 727, and step 735 is specifically to boost the voltage of the currently applied alternating electric signal in a manner of a DC voltage amplitude increment of 0.03 V per second.

[0289] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 718, step 730, and step 739 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and continuing for 3 minutes.

[0290] The process of stopping applying the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in step 721 is specifically as follows:

[0291] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0292] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the electrode units 33 are applied with an alternating electrical signal to the end where the electrode units 33 are subjected to temperature collection; or

[0293] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal collection terminals 1 thereof; or

[0294] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding analog-to-digital converter 53; or

[0295] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0296] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 725 is specifically as follows:

[0297] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating power line 57; or

[0298] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all ends from the end where the electrode units 33 in the over-temperature zone apply an alternating electrical signal to the end where the electrode units 33 in the over-temperature zone collect temperature; or

[0299] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch all signal input terminals 2 for applying alternating electrical signals to each electrode unit 33 in the over-temperature region to their signal collection terminals 1; or

[0300] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0301] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0302] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrodes 13 to alternately apply alternating electric fields with different directions, and each electrode 13 can alternately switch between applying alternating electric signals and transmitting temperature detection signals.

[0303] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field treatment system 100 of the embodiment of the present application is also provided with a third preset temperature t3, which is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The embodiment of the present application also provides an alternating electric signal control method based on a temperature detection signal, which is used in the above tumor electric field treatment system, Fig.16 As shown, the alternating electric signal control method includes:

[0304] Step 810: Start the tumor therapeutic field system 100;

[0305] Step 811: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0306] Step 812: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0307] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, and execute step 814 when there is no electrode unit 33 whose temperature exceeds the first preset temperature t1; and execute step 815 when there is an electrode unit 33 whose temperature exceeds the first preset temperature t1;

[0308] Step 814: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0309] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 816; when there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 817;

[0310] Step 816: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 812;

[0311] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. If there is no electrode unit 33 whose temperature exceeds the third preset temperature t3, execute step 818; if there is an electrode unit whose temperature exceeds the third preset temperature t3, execute step 819;

[0312] Step 818: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0313] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821;

[0314] Step 820: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0315] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0316] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 823 when the number of over-temperature areas exceeds the preset number threshold; and execute step 826 when the number of over-temperature areas does not exceed the preset number threshold;

[0317] Step 823: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 824;

[0318] Step 824: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and executing step 825;

[0319] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. When the electrode sheet 13 does not have an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 811. When the electrode sheet 13 has an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 824.

[0320] Step 826: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0, and execute step 827 when the area is the over-temperature area, and execute step 828 when the area is the non-over-temperature area;

[0321] Step 827: stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 835;

[0322] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0323] Step 829: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0324] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0325] Step 831: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and execute step 835;

[0326] Step 832: Determine whether there is an electrode unit 33 in the non-overtemperature area whose temperature exceeds the third preset temperature t3. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the third preset temperature t3, execute step 833. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the third preset temperature t3, execute step 834.

[0327] Step 833: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0328] Step 834: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of further reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0329] Step 835: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to reacquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 836 or step 838, wherein the temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area;

[0330] Step 836: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. When the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0331] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0332] Step 838: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 839. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the first preset temperature t1, execute step 840.

[0333] Step 839: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0334] Step 840: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 841. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the second preset temperature t2, execute step 842.

[0335] Step 841: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged and return to step 812;

[0336] Step 842: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the third preset temperature t3. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the third preset temperature t3, execute step 843. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the third preset temperature t3, execute step 844.

[0337] Step 843: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0338] Step 844: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 845. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 821.

[0339] Step 845 : Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812 .

[0340] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 811 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0341] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that applies an alternating electrical signal to each electrode unit 33; or

[0342] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0343] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0344] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 812, step 824, and step 835 is specifically as follows:

[0345] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected, and sequentially close the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 in time division to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0346] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal collection terminals 1, and sequentially close the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in time division to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0347] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and closing the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0348] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electrical signal to transmitting a direct current signal or a temperature detection signal, and the control switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0349] The first preset temperature in step 813, step 825, step 828, step 836, and step 838 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 815, step 830, and step 840 is 40.4°C to 40.6°C, preferably 40.5°C; the third preset temperature in step 817, step 832, and step 842 is 40.7°C to 40.9°C, preferably 40.8°C; the preset temperature threshold in step 819 and step 844 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 822 is preferably 2.

[0350] The process of continuing to apply the alternating electric signal described in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows:

[0351] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0352] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0353] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the respective signal input ends 2 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0354] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that their respective signal input terminals 2 are closed and the signal collection terminal 1 is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0355] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0356] The method of increasing the voltage or current amplitude of the currently applied alternating electric signal in step 814, step 829, and step 839 is to continue to apply the alternating electric signal by boosting the currently applied alternating electric signal with a DC voltage amplitude increment of 0.03V per second and then continue to apply the alternating electric signal.

[0357] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and continuing for 3 minutes.

[0358] The process of stopping applying the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in step 823 is specifically as follows:

[0359] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0360] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the electrode units 33 are applied with an alternating electrical signal to the end where the electrode units 33 are subjected to temperature collection; or

[0361] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying alternating electrical signals to the electrode units 33 to the signal collection terminals 1 thereof; or

[0362] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding analog-to-digital converter 53; or

[0363] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0364] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 827 is specifically as follows:

[0365] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating power line 57; or

[0366] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all ends from the end where the electrode units 33 in the over-temperature zone apply an alternating electrical signal to the end where the electrode units 33 in the over-temperature zone collect temperature; or

[0367] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch all signal input terminals 2 for applying alternating electrical signals to each electrode unit 33 in the over-temperature region to their signal collection terminals 1; or

[0368] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0369] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0370] When the tumor electric field therapy system 100 is in a standby state before starting work, no alternating electric signal is applied to the electrode unit 33, and the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switch 55 (55-1 to 55-5) to switch to the signal acquisition terminal 1, and the control switches 54 (54-1 to 54-4) are turned on in turn, and the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to each row of electrode units 33 (33-1 to 33-20) in turn.

[0371] When the control switch 54-1 is turned on, the control switches (54-2, 54-3, 54-4) are all turned off, and the bidirectional switching switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-1 to 33-5);

[0372] When the control switch 54-2 is turned on, the control switches (54-1, 54-3, 54-4) are all turned off, and the bidirectional switching switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-6 to 33-10);

[0373] When the control switch 54-3 is turned on, the control switches (54-1, 54-2, 54-4) are all turned off, and the bidirectional switching switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-11 to 33-15);

[0374] When the control switch 54-4 is turned on, the control switches (54-1, 54-2, 54-3) are all turned off, and the bidirectional switching switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-16 to 33-20).

[0375] The first controller 51 receives the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits it to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the alternating electric signal applied to each electrode unit 33 through the second controller 37.

[0376] Although various operations are depicted in the drawings as being in a particular order, this should not be understood as requiring that the operations must be performed in the particular order shown or in sequential order, nor should it be understood as requiring that all illustrated operations must be performed to achieve desirable results.

[0377] Embodiment 2:

[0378] The main concept of the above-mentioned tumor electric field treatment system 100 is that the adapter 20 and the electric field generator 30 are both provided with an alternating power line 57, which controls the alternating electric signals of all electrode units 33 on an electrode sheet 13 to change synchronously, such as the voltage or current rising or falling at the same time, and cannot simultaneously apply different alternating electric signals to the electrode units 33 of different columns, such as voltages or currents of different magnitudes. Figures 17 to 20Another tumor electric field treatment system 100' is described below. Its main concept is the same as that of the above-mentioned tumor electric field treatment system 100, except that: each column group electrode unit 33' on the corresponding electrode sheet 13' in the adapter 20' and the electric field generator 30' of the tumor electric field treatment system 100' is provided with a corresponding alternating power line 57', so that different alternating electric signals, such as voltages or currents of different magnitudes, can be applied to different column groups of electrode units 33' at the same time.

[0379] Fig.18 This is a circuit connection diagram of an electrode sheet 13', an adapter 20', and an electric field generator 30' of another tumor electric field therapy system 100' of an embodiment of the present application. The tumor electric field therapy system 100' includes: at least one pair of electrode sheets 13', an adapter 20' connected to the electrode sheets 13', and an electric field generator 30' connected to the adapter 20'.

[0380] The specific structure of the electrode sheet 13 ′ is the same as that of the electrode sheet 13 , which will not be described in detail here.

[0381] The specific structure of the adapter 20' is similar to the above-mentioned adapter 20, except that: Fig.18 and Fig.19 , the adapter 20' is provided with 5 alternating power lines 57' corresponding to each electrode sheet 13', and the 5 alternating power lines 57' are arranged one by one in correspondence with the 5 column groups of electrode units 33' of one electrode sheet 13', and each electrode sheet 13' is provided with a corresponding bidirectional switch 55' and a grounding switch 54', and the signal input end 2 of the bidirectional switch 55' is electrically connected to a separate alternating power line 57', so that the tumor electric field treatment system 100' can apply different alternating electrical signals, such as different voltages or currents, to different column groups of electrode units 33' in each electrode sheet 13' as needed.

[0382] The specific structure of the electric field generator 30' is similar to the above electric field generator 30, except that: Fig.18 and Fig. 20 A power switch 40' is provided for each alternating power line 57' connected between the AC signal generator 39' and the adapter 20' to individually control the on and off of the alternating electrical signal of each column group electrode unit 33' of each electrode sheet 13'.

[0383] Specifically, refer to Fig.18 and Fig.19As shown, the adapter 20' includes: a first controller 51', multiple groups of ADC units 52' connected to the first controller 51', multiple groups of piezoelectric resistors 53' and multiple groups of control switches 54' corresponding to the multiple groups of ADC units 52', multiple groups of two-way switching switches 55' corresponding to the multiple groups of ADC units 52', a first communication unit 56', multiple alternating power lines 57' connected to each group of two-way switching switches 55' corresponding to each other, and a first power module 58' connected to the first communication unit 56', the first controller 51' and the multiple groups of ADC units 52' at the same time, and the first power module 58' provides a DC power supply VCC for each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (unnumbered), and the multiple circuit lines (unnumbered) are electrically connected to the multiple ground lines 18' and the multiple dual-purpose signal lines 19' in the substrate 31' of the electrode sheet 13' through the first cables 15' of the corresponding electrode sheet 13'. The multiple circuit lines (unnumbered) include multiple different alternating power lines 57' that transmit alternating electrical signals to the corresponding electrode sheets 13' and are electrically connected to the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13', multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13' and are used to supply power to the temperature detection units 35' of the electrode sheets 13' or to transmit the temperature detection signals of the electrode sheets 13', and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18' in the substrate 31' of the corresponding electrode sheets 13'. The number L of circuit lines electrically connected between the adapter 20' and one electrode sheet 13' is equal to the sum of the number of rows and the number of columns of the electrode units 33' of the electrode sheet 13'; the number H of circuits electrically connected between the adapter 20' and X electrode sheets 13' is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13', that is, H=XL=X*(M+N). The number of groups of control switches 54' and the number of groups of bidirectional switching switches 55' are both related to the number of electrode sheets 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and is not less than the number of electrode sheets 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' are both the same as the number of electrode sheets 13'.

[0384] For example, each group of control switches 54' is provided with a plurality of control switches 54', and the plurality of control switches 54' are respectively connected to the adapter 20' and are respectively electrically connected to circuit lines (unnumbered) corresponding one by one to the multi-way grounding lines 18' of a corresponding electrode sheet 13', and are configured to control the conduction or disconnection of the multi-way grounding lines 18'. The circuit lines (unnumbered) of the multi-way grounding lines 18' that are electrically connected one by one to the electrode sheet 13' are grounded at one end close to the control switches 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding lines 18' of the substrate 31' of the corresponding electrode sheet 13', and the two are equal in the present embodiment. Fig.18 As shown, in this embodiment, the plurality of control switches 54' are respectively a first control switch 54-1', a second control switch 54-2', a third control switch 54-3' and a fourth control switch 54-4'. The plurality of control switches 54' in the same group control the closing or opening of the corresponding grounding line 18' of the same electrode sheet 13' one by one. The first control switch 54-1' is used to control the closing or disconnection of the first grounding line 18-1' of the corresponding electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-1' to electrode unit 33-5' in the first row group 33 of the electrode sheet 13'; the second control switch 54-2' is used to control the closing or disconnection of the second grounding line 18-2' of the electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of the temperature detection units 35' corresponding to the five electrode units 33' from electrode unit 33-6' to electrode unit 33-10' in the second row group 33' of the electrode sheet 13'; The control switch 54-3' is used to control the closing or disconnection of the third grounding line 18-3' of the electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-11' to electrode unit 33-15' in the third row group 33' of the electrode sheet 13'; the fourth control switch 54-4' is used to control the closing or disconnection of the fourth grounding line 18-4' of the electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the five electrode units 33' from electrode unit 33-16' to electrode unit 33-20' in the fourth row group 33' of the electrode sheet 13'. The above-mentioned control switch 54' can be a mechanical switch, such as a relay. The control switch 54' can also be an electronic switch, and each control switch 54' can be opened and closed by an additional first controller 51'.

[0385] In the present embodiment, the plurality of control switches 54' are all electronic switches. The first controller 51' is connected in communication with the plurality of control switches 54', and is used to sequentially and cyclically control the opening and closing states of the plurality of control switches 54' in each group of control switches 54', and then sequentially and individually conduct each of the plurality of grounding wires 18' of the corresponding electrode sheet 13' and cooperate with the switching of the corresponding two-way switching switch 55', so as to collect the temperature of the patient's body surface detected by all the temperature detection units 35' on the electrode sheet 13'. The number of each group of control switches 54' is not less than the number of grounding wires 18' of the substrate 31' of the corresponding electrode sheet 13'. In the present embodiment, the number of each group of control switches 54' is the same as the number of grounding wires 18' of the corresponding electrode sheet 13'.

[0386] Each set of two-way switching switches 55' is provided with a plurality of two-way switching switches 55', and the plurality of two-way switching switches 55' in each set are respectively connected to the adapter 20' and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19' of the corresponding electrode sheet 13'. The number of two-way switching switches 55' in each set of two-way switching switches 55' is related to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', which is greater than or equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', and in this embodiment, the two are equal. Each bidirectional switch 55' has two ends marked as 1 and 2. The signal acquisition ends 1 of the multiple bidirectional switches 55' in the same group are electrically connected one by one to the corresponding detection channels of the multiple detection channels of a corresponding group of ADC units 52' through temperature sampling points (unnumbered). The signal input ends 2 of each bidirectional switch 55' in the same group are electrically connected to the corresponding different alternating power lines 57', and are configured to control the multi-channel dual-purpose signal line 19' to access the corresponding different alternating power lines 57' to transmit alternating electrical signals or to access the corresponding detection channels of the corresponding group of ADC units 52' to receive the temperature detection signals output by the temperature detection unit 35'.

[0387] like Fig.18As shown, taking the electrical connection between an electrode sheet 13' and an adapter 20' as an example, in this embodiment with 20 electrode units 33', the plurality of bidirectional switches 55' are respectively a first bidirectional switch 55-1', a second bidirectional switch 55-2', a third bidirectional switch 55-3', a fourth bidirectional switch 55-4' and a fifth bidirectional switch 55-5'. The plurality of bidirectional switches 55' in the same group respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of a corresponding one of the multiplexed dual-purpose signal lines 19' of the same electrode sheet 13'. Specifically, the first bidirectional switch 55-1' is used to control the first dual-purpose signal line 19-1' of the corresponding electrode sheet 13' to switch between the transmission of the alternating electric signal output by the alternating power line 57-1' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16' in the first column group of the electrode sheet 13' and the conduction of the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16' in the first column group. The signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-16' is switched between the conduction and the corresponding control switch 54-1', the control switch 54-2', the control switch 54-3', and the control switch 54-4' are coordinated to make the first column of electrode units 33-1', electrode units 33-6', electrode units 33-11', and electrode units 33-16' transmit separate alternating electrical signals to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. The second bidirectional switch 55-2' is used to control the switching of the second dual-purpose signal line 19-2' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-2' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-2', the electrode unit 33-7', the electrode unit 33-12', and the electrode unit 33-17' in the second column group of the electrode sheet 13' and the conduction of the electrode unit 33-2', the electrode unit 33-7', the electrode unit 33-12', and the electrode unit 33-17' in the second column group. The signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-17' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the second column electrode unit 33-2', electrode unit 33-7', electrode unit 33-12', and electrode unit 33-17' transmit a separate alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35' corresponding to these electrode units 33' to the corresponding ADC unit 52';The third bidirectional switch 55-3' is used to control the third dual-purpose signal line 19-3' of the corresponding electrode sheet 13' to switch between the transmission of the alternating electric signal output by the alternating power line 57-3' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-3', the electrode unit 33-8', the electrode unit 33-13', and the electrode unit 33-18' in the third column group of the electrode sheet 13' and the conduction of the electrode unit 33-3', the electrode unit 33-8', the electrode unit 33-13', and the electrode unit 33-18' in the third column group. The signal end 35-2' of each temperature detection unit 35' corresponding to 33-18' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the third column electrode unit 33-3', electrode unit 33-8', electrode unit 33-13', and electrode unit 33-18' transmit a separate alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. The fourth bidirectional switch 55-4' is used to control the switching of the fourth dual-purpose signal line 19-4' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-4' and the transmission of the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-4', the electrode unit 33-9', the electrode unit 33-14', and the electrode unit 33-19' in the fourth column group of the electrode sheet 13' and the conduction of the electrode unit 33-4', the electrode unit 33-9', the electrode unit 33-14', and the electrode unit 33-19' in the fourth column group. The signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-19' is switched on and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the fourth column electrode unit 33-4', electrode unit 33-9', electrode unit 33-14', and electrode unit 33-19' transmit a separate alternating electrical signal to the patient or output the temperature detection signal collected by the temperature detection unit 35' corresponding to these electrode units 33' to the ADC unit 52';The fifth bidirectional switch 55-5' is used to control the fifth dual-purpose signal line 19-5' of the corresponding electrode sheet 13' to switch between the alternating electric signal output by the alternating power line 57-5' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' of the electrode unit 33-5', the electrode unit 33-10', the electrode unit 33-15', and the electrode unit 33-20' in the fifth column group of the electrode sheet 13' and the conduction of the electrode unit 33-5', the electrode unit 33-10', the electrode unit 33-15', and the electrode unit 33-20' in the fifth column group. The signal end 35-2' of each temperature detection unit 35' corresponding to 33-20' conducts the switching between the two and cooperates with the corresponding control switch 54-1', control switch 54-2', control switch 54-3', and control switch 54-4', so that the fifth column electrode unit 33-5', electrode unit 33-10', electrode unit 33-15', and electrode unit 33-20' transmit a separate alternating electrical signal to the patient or output the temperature detection signals collected by the temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. When the signal input end 2 of each group of two-way switching switches 55' is turned on and the signal collection end 1 is turned off, the alternating electrical signal can be transmitted to each electrode unit 33' of each column group of the corresponding electrode sheet 13' through different alternating power lines 57'. When the signal collection end 1 of each group of two-way switching switches 55' is turned on and the signal input end 2 is turned off, it can cooperate with each control switch 54' in the corresponding group of control switches 54' to transmit the temperature detection signal collected by the temperature detection unit 35' of each electrode element 33' on the electrode sheet 13' in a time-sharing manner. The above-mentioned two-way switching switch 55' can be a mechanical switch, such as a relay. The two-way switching switch 55' can also be an electronic switch, and each two-way switching switch 55' can be switched by an additional first controller 51'. ;

[0388] In this embodiment, the plurality of groups of two-way switches 55' are all electronic switches. The first controller 51' is in communication connection with the plurality of groups of two-way switches 55', and is used to control the plurality of two-way switches 55' in each group of two-way switches 55' to switch between their respective signal acquisition terminals 1 and signal input terminals 2, and to coordinate the closing or opening of the corresponding control switch 54', so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35' on the electrode sheet 13' or transmit an alternating electrical signal to the patient.

[0389] In this embodiment, each group of ADC units 52' is electrically connected to the signal acquisition terminals 1 of the multiple bidirectional switching switches 55' in the corresponding group of bidirectional switching switches 55' through the multi-channel circuit lines (unnumbered) in the adapter 20', and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19' of the corresponding electrode sheet 13', and convert the temperature detection signal from an analog signal to a digital signal. Each group of ADC units 52' includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding dual-purpose signal line 19' in the multi-channel dual-purpose signal line 19' through the corresponding bidirectional switching switch 55'. Fig.18 As shown, each group of ADC units 52' includes 5 detection channels A, B, C, D, and E, which are the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1' through the signal acquisition terminal 1 of the first two-way switch 55-1', the second detection channel B is connected to the second dual-purpose signal line 19-2' through the signal acquisition terminal 1 of the second two-way switch 55-2', the third detection channel C is connected to the third dual-purpose signal line 19-3' through the signal acquisition terminal 1 of the third two-way switch 55-3', the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' through the signal acquisition terminal 1 of the fourth two-way switch 55-4', and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5' through the signal acquisition terminal 1 of the fifth two-way switch 55-5'. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature detection unit 35' corresponding to the electrode unit 33' to which the corresponding dual-purpose signal line 19' is connected. In addition, each detection channel A, B, C, D, E is connected to a first power module 58' for providing detection voltage to the detection channel A, B, C, D, E via a corresponding voltage divider resistor 53' in the adapter 20'. The first power module 58' provides direct current.

[0390] In this embodiment, the first communication unit 56' is configured to obtain the digital signals output by the multiple groups of ADC units 52' and send the digital signals to the electric field generator 30'. The electric field generator 30' is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33' of the electrode sheet 13' according to the received digital signal. Exemplarily, when any of the multiple digital signals received exceeds the preset threshold value, it means that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds the preset threshold temperature (for example, 41°C, 42°C, etc.), at this time, the voltage of the alternating electric signal output by the electric field generator 30' can be appropriately reduced or stopped to avoid the electrode unit 33' of the electrode sheet 13' from being too high in temperature when the alternating electric signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined according to the human safety threshold value. The first communication unit 56' is controlled by the first controller 51' and transmits the digital signals converted by the multiple groups of ADC units 52' in series. In this embodiment, the preset threshold temperature may be a value within the range of 36°C-45°C.

[0391] refer to Fig.18In this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30', and is configured to supply power to the first controller 51', multiple groups of ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is connected between each electrode sheet 13' and the adapter 20', and the first connector 60' is suitable for connecting the corresponding electrode sheet 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30', and the second connector 70' is suitable for connecting the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' provided at an end of the second cable 25' away from the first controller 51' and a second socket 72' provided on the electric field generator 30'. The second plug 71' and the second socket 72' are push-type spring connectors, that is, the second connector 70' uses a connector to connect the adapter 20' and the electric field generator 30'. Each first connector 60' such as X1, Y1, X2 and Y2 is connected to the second connector 70' through a corresponding 5-way alternating power line 57', and the first connector 60' such as X1, Y1, X2 and Y2 is also connected to a corresponding group of control switches 54' and a corresponding group of ADC units 52', wherein each first connector 60' is connected to the second connector 70' and a corresponding group of ADC units 52' through a corresponding group of two-way switching switches 55'. The second cable 25' has 8 conductors, including 4 five-core conductors 1 to 4 which are electrically connected to the corresponding 5-way alternating power lines 57' and are used to transmit different alternating electrical signals, 1 conductor 5 which is electrically connected to the data receiving line RX' of the first communication unit 56', 1 conductor 6 which is electrically connected to the data sending line TX' of the first communication unit 56', 1 conductor 7 which is electrically connected to the VCC power line of the first power module 58', and 1 conductor 8 which is electrically connected to the GND line of the first power module 58'. The second connector 70' is connected to the first communication unit 56' through the data receiving line RX' and the data sending line TX', the VCC pin of the second connector 70' is connected to the VVC power line of the first power module 58', the GND pin of the second connector 70' is connected to the GND line of the first power module 58' and is grounded, and the VCC pin of the second connector 70' is also connected to the corresponding group of voltage dividers 53' and the corresponding group of ADC units 52' through the VCC power line of the first power module 58'.

[0392] refer to Fig.18 and Fig. 20The electric field generator 30' includes: a second power module 32', a second controller 37', an AC signal generator 39', a second communication unit 38' and a plurality of power switches 40'. The VCC pin of the second connector 70' is also electrically connected to the VCC power line of the second power module 32', and the GND pin of the second connector 70' is grounded through the GND line of the second power module 32'. The second power module 32' is also connected to the second controller 37' and the AC signal generator 39' respectively and supplies power to them. The second communication unit 38' is electrically connected to the wire 5 of the second connector 70' through its data receiving line RX' and is electrically connected to the wire 6 of the second connector 70 through its data sending line TX', thereby realizing information interaction between the electric field generator 30' and the adapter 20'. The second controller 37' is also electrically connected to the second communication unit 38', the AC signal generator 39' and the multiple groups of power switches 40'. The second controller 37' is configured to control the opening and closing of each power switch 40' in each group of the multiple power switches 40' and adjust the relevant parameters of the different alternating electrical signals applied by the AC signal generator 39 according to the relevant digital signals received by the second communication unit 38' from the adapter 20'. The AC signal generator 39 is electrically connected to the wires 1 to 4 that transmit different alternating electrical signals to the second connector 70' through the multiple groups of power switches 40'. Each group of power switches 40' in the multiple groups of power switches 40' includes multiple power switches 40', and the multiple groups of power switches 40' are arranged in a one-to-one correspondence with the multiple electrode sheets 13'. Each group of power switches 40' is electrically connected to a corresponding five-core wire 1, 2, 3, 4 for transmitting alternating electrical signals in the second connector 70' through a five-core AC power line 41-1', 41-2', 41-3', 41-4' and is electrically connected to the corresponding electrode sheet 13' through the corresponding five-core wire 1, 2, 3, 4 of the second connector 70', so as to transmit different alternating electrical signals to each electrode sheet 13. The AC signal generator 39' is electrically connected to multiple groups of power switches 40' through a five-core AC power line 41'. Specifically, the number of groups of power switches 40' of the electric field generator 30' is related to the number of electrode sheets 13'. In this embodiment, the number of groups of power switches 40' is equal to the number of electrode sheets 13' and both are 4. The number of each group of power switches 40' is related to the number of column groups of the corresponding electrode sheets 13'. In this embodiment, the number of each group of power switches 40' is equal to the number of column groups of the corresponding electrode sheets 13' and both are 5. The plurality of power switches 40' include a first power switch 40-1', a second power switch 40-2', a third power switch 40-3' and a fourth power switch 40-4' which are electrically connected to the five-core wires 1 to 4 of the second connector 70' in a one-to-one correspondence. One end of the first power switch 40-1' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30'.The other end is electrically connected to the corresponding five-core wire 1 for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-1', and is electrically connected to the five-way alternating power line 57' at the port X1' of the adapter 20' through the five-core wire 1 of the second connector 70', the five-way alternating power line 57' at the port X1' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port X1 of the adapter 20' is electrically connected to the corresponding electrode sheet 13', so as to control whether the AC signal generator 39' sends an alternating current to the five electrodes 13' corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to the port X1 of the adapter 20'. The electrode units 33' in the column group transmit different alternating electric signals; one end of the second group of power switches 40-2' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 2 for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-2', and is electrically connected to the five-way alternating power line 57' at the port Y1' of the adapter 20' through the five-core wire 2 of the second connector 70', and the five-way alternating power line 57' at the port Y1' of the adapter 20' is electrically connected to the first connector 60', and the first connection at the port Y1' of the adapter 20' is electrically connected to the first connector 60'. The connector 60' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the five column groups corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to the adapter 20' port Y1'; one end of the third group of power switches 40-3' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30', and the other end is electrically connected to the corresponding five-core wire 3' for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-3' and is connected to the adapter 20' at the end through the five-core wire 3' of the second connector 70'. The five-way alternating power line 57' at the port X2' of the adapter 20' is electrically connected, the five-way alternating power line 57' at the port X2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port X2' of the adapter 20' is electrically connected to the corresponding electrode sheet 13', so as to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the five column groups corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to the port X2' of the adapter 20'; one end of the fourth group of power switches 40-4' is electrically connected to the AC signal generator 39' through the five-core AC power line 41' of the electric field generator 30',The other end is electrically connected to the corresponding five-core wire 4' for transmitting alternating electric signals in the second connection 70' through a five-core AC power line 41-4' and electrically connected to the five-way alternating power line 57' at the port Y2' of the adapter 20' through the five-core wire 4 of the second connector 70', the five-way alternating power line 57' at the port Y2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port Y2' of the adapter 20' is electrically connected to the corresponding electrode sheet 13', so as to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the five column groups corresponding to the five-way alternating power lines 57' in the electrode sheet 13' electrically connected to the port Y1' of the adapter 20'.

[0393] The following will refer to Figures 18 to 20 The working principle of the tumor electric field treatment system 100' of this embodiment is described in detail.

[0394] It should be noted that the working principle of temperature collection of tumor therapeutic field system 100 ′ is the same as that of temperature collection of tumor therapeutic field system 100 , and will not be described in detail here.

[0395] The working principle of applying alternating electric signals of tumor electric field treatment system 100 ′ is similar to that of tumor electric field treatment system 100 , except that: this embodiment can apply different alternating electric signals to electrode units 33 of different columns at the same time, which is more flexible.

[0396] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33' of a certain electrode sheet 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the signal input end 2 of each of the multiple bidirectional switching switches 55' of a group of bidirectional switching switches 55' electrically connected to the electrode sheet 13' to be turned on and the signal acquisition end 1 to be turned off, and controls a group of power switches 40' electrically connected to the electrode sheet 13' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply different alternating electric signals to each column group of electrode units 33' of the electrode sheet 13' through different alternating power lines 57', and the voltage or current of the different applied alternating electric signals are adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two column groups to connect to different alternating power lines 57 ′, so that different alternating electrical signals are applied to the electrode units 33 of each column group based on different alternating power lines 57 ′.

[0397] It should be noted that, in other embodiments, a group of bidirectional switches 55' electrically connected to a certain electrode sheet 13' can be controlled by the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' to apply different alternating electric signals to some electrode units 33' of the electrode sheet 13' in the same time period. For example, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls a group of two-way switches 55' electrically connected to the electrode sheet 13', and controls a group of power switches 40' electrically connected to the electrode sheet 13' and a power switch 40' corresponding to the first two-way switch 55-1' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply an alternating electric signal to the first column group electrode unit 33-1', electrode unit 33-6', electrode unit 33-11', and electrode unit 33-16' of the electrode sheet 13' through the corresponding alternating power line 57', and the voltage or current of the applied alternating electric signal is adjustable. It should be noted that, in other embodiments, different alternating electrical signals may be applied to two-column groups, three-column groups or four-column groups of electrode units 33 simultaneously in the same time period, which will not be described in detail here.

[0398] It should be noted that the control switch 54' electrically connected to the multi-way grounding wires 18' of the electrode sheet 13' and the bidirectional switch 55' electrically connected to the multi-way dual-purpose signal wires 19' of the electrode sheet 13' in the embodiment of the present application are both provided in the adapter 20', but in other embodiments, the control switch 54' electrically connected to the grounding wire 18' and the bidirectional switch 55' electrically connected to the dual-purpose signal wire 19' can also be provided on the electrode sheet 13' or provided in the electric field generator 30', which will not be described in detail here. In addition, the ADC unit 52' provided in the adapter 20' can also be provided in the electric field generator 30' and directly controlled by the second controller 37'.

[0399] The tumor electric field therapy system 100' of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 33' on the electrode sheet 13' without increasing the weight of the electrode sheet 13' or the core of the first cable 15' electrically connected to the electrode sheet 13', and then determine whether the electrode sheet 13' is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35' of the electrode sheet 13' is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13' needs to be replaced based on the number of faulty or abnormal temperature detection units 35'; or identify the type of the electrode sheet based on the obtained temperature detection signal when the electrode sheet 13' is qualified; or determine whether the electrode unit 33' of the electrode sheet 13' is over-temperature based on the obtained temperature detection signal when the electrode sheet 13' is qualified, and then control the alternating electric signal applied to the electrode sheet 13' or the electrode units 33' of the corresponding column of the electrode sheet 13' to avoid low-temperature burns on the patient's body surface when the tumor is treated by the electrode sheet 13'. In addition, the substrate 31' of the electrode sheet 13' of the present application is electrically connected to the same electrode unit 33' and the signal end 35-2' of the corresponding temperature detection unit 35' through the same dual-purpose signal line 19'. While it can transmit both the alternating electric signal and the direct current signal for temperature signal collection and the collected temperature detection signal through the dual-purpose signal line 19', it also greatly reduces the number of conductive traces (grounding line 18', dual-purpose signal line 19') arranged thereon, reduces the wiring difficulty of the substrate 31', simplifies the manufacturing process, reduces the weight of the substrate 31', and reduces the manufacturing cost. The electrode sheet 13' of the present application can also switch between applying an alternating electric signal for tumor treatment and transmitting a direct current signal for temperature collection and transmitting the collected temperature detection signal through the combined control of a control switch 54' electrically connected to the grounding line 18' arranged thereon and a bidirectional switching switch 55' electrically connected to the dual-purpose signal line 19'.

[0400] Specifically, when it is necessary to apply an alternating electric signal to the patient through each electrode unit 33' of a certain electrode sheet 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls all the control switches 54' in a group of control switches 54' corresponding to the electrode sheet 13' to be disconnected, and at the same time controls all the bidirectional switching switches 55' in a group of bidirectional switching switches 55' corresponding to the electrode sheet 13' to be switched to their respective signal input terminals 2, so that the signal acquisition terminals 1 of the bidirectional switching switches 55' are all disconnected and the signal input terminals 2 are all turned on, so that the dual-purpose signal lines 19' of the electrode sheet 13' are electrically connected to the adapter 20' and the multi-channel alternating power lines 57' corresponding to the electrode sheet 13', thereby transmitting the same or different alternating electric signals to each electrode unit 33' of the electrode sheet 13'. When the temperature detection signals of the temperature detection units 35' corresponding to all the electrode units 33' of the detected electrode sheet 13' are much lower than the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' controls the AC signal generator 39 through its second controller 37' to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13' through the corresponding multi-channel alternating power lines 57' of the adapter 20', so that the pair of electrode sheets 13' continue to apply the alternating electric signal; when the temperature detection signals of the temperature detection units 35' corresponding to all the electrode units 33' of the detected electrode sheet 13' are lower than but close to the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39' through the second controller 37', thereby reducing the voltage or current of the alternating electric signal. The voltage or current of the alternating electric signal applied to the pair of electrode sheets 13' is low; when it is detected that the temperature detection signal of the temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode sheet 13' is greater than the preset temperature threshold, the electric field generator 30' controls a group of power switches 40' electrically connected to the electrode sheet 13' to be disconnected through the second controller 37' to stop applying the alternating electric signal to the electrode sheet 13'; or the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls all the two-way switching switches 55' in a group of two-way switching switches 55' electrically connected to the electrode sheet 13' to switch from their signal input terminal 2 to the signal collection terminal 1, that is, controls all the two-way switching signal collection terminals 1 of a group of two-way switching switches 55' electrically connected to the electrode sheet 13' to be turned on and all the signal input terminals 2 to be turned off, thereby stopping applying the alternating electric signal to the electrode sheet 13';Or, when it is detected that a temperature detection signal of a temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode sheet 13' is greater than a preset temperature threshold, the second controller 37' of the electric field generator 30' controls a group of power switches 40' electrically connected to the electrode sheet 13' to continue to be turned on, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' controls a bidirectional switch 55' electrically connected to the electrode unit 33' of the electrode sheet 13' to switch from its signal input end 2 to its signal acquisition end 1, and the second controller 37' of the electric field generator 30' or the first controller 21' of the adapter 20' simultaneously controls the electrode unit 33' whose temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold. The remaining two-way switches 55' electrically connected to the electrode unit 33' continue to maintain electrical connection with their respective signal input terminals 2, so as to stop applying alternating electric signals to all electrode units 33' in the column where the electrode unit 33' whose temperature detection signal of the electrode sheet 13' exceeds the preset temperature threshold, and continue to apply alternating electric signals to the remaining column electrode units 33' whose temperature detection signals of the electrode sheet 13' do not exceed the preset temperature threshold, and the alternating electric signals applied to the remaining column electrode units 33' can be the same or different, for example, the alternating electric signals are applied in a manner of reducing the voltage or current amplitude of the alternating electric signals for the columns whose temperature detection signals do not exceed the preset temperature threshold but are closer to the preset temperature threshold, and the alternating electric signals are applied in a manner of increasing the voltage or current amplitude of the alternating electric signals for the columns whose temperature detection signals do not exceed the preset temperature threshold but are farther away from the preset temperature threshold. In this way, the alternating electric signal application control method based on the temperature detection signal of the tumor electric field treatment system 100' is realized. ;

[0401] It should be noted that the alternating electric signal application method, electrode sheet temperature detection method, electrode sheet temperature abnormality detection method, control method, and electrode sheet type identification method of the tumor electric field treatment system 100' of this embodiment are similar to the control method of the aforementioned tumor electric field treatment system 100, with the difference that: the tumor electric field treatment system 100' of this embodiment can also apply different alternating electric signals, such as different voltages or currents, to the electrode units 33' in each area (i.e., each column group) at the same time according to the temperature of the electrode units 33' in each area to prevent the electrode units 33' in the corresponding area from exceeding the preset temperature threshold, so as to apply the electric field continuously for a long time and improve the treatment effect.

[0402] Specifically, the tumor electric field treatment system 100' of this embodiment can be used Figure 8 The electrode sheet temperature detection method shown in the figure determines the temperature of each electrode unit 33' in the electrode sheet 13'. Figure 8 , I will not go into details here.

[0403] The tumor electric field treatment system 100 of this embodiment can be used Fig. 9 The electrode sheet temperature abnormality detection method shown in the figure determines whether the electrode sheet 13' is abnormal. Fig. 9 , I will not go into details here.

[0404] The tumor electric field treatment system 100 of this embodiment can be used Fig.21 The control method of the tumor electric field treatment system shown controls the intensity of the alternating electric signal applied to the electrode unit 33', and specifically includes the following steps:

[0405] Step 210 ′: Control the switching unit so that the dual-purpose signal line 19 ′ corresponding to at least one column group in the corresponding electrode sheet 13 ′ is connected to the corresponding temperature sampling point.

[0406] Step 220 ′: Control the control switch 54 ′ corresponding to each row group to sample the analog temperature signal of the corresponding electrode unit 33 ′ based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 ′ in each electrode sheet 13 ′.

[0407] Step 240 ′: Control the intensity of the alternating electric signal applied to the electrode unit 33 ′ according to the temperature detection signal.

[0408] Specifically, when the electrode sheet 13' is determined not to need to be replaced, the alternating electric signal applied to each electrode unit 33' in the electrode sheet 13' is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35' corresponding to each electrode unit 33' in the electrode sheet 13'.

[0409] In some embodiments, controlling the intensity of the alternating electric signal applied to the electrode unit 33' according to the temperature detection signal in step 240' specifically includes the following steps:

[0410] Step 241 ′: comparing the temperature of each electrode unit 33 ′ in the electrode sheet 13 ′ with a preset temperature threshold according to the temperature detection signal.

[0411] Step 242 ′: Control the strength of the alternating electric signal according to the comparison result.

[0412] In some embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242' specifically includes:

[0413] Step 2421': When the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, stop applying the alternating electric signal to the electrode unit 33' of the electrode sheet 13'. Specifically, when there is a temperature detection signal exceeding the preset temperature threshold among the temperature detection signals of all electrode units 33' of the electrode sheet 13' obtained, stop applying the alternating electric signal to the electrode unit 33' of the electrode sheet 13'. When the temperature detection signals of each electrode unit 33' in the electrode sheet 13' obtained do not exceed the preset temperature threshold, continue to apply the alternating electric signal to each electrode unit 33' of the electrode sheet 13'.

[0414] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33' of the electrode sheet 13' in step 2421' specifically includes: stopping applying the alternating electric signal to all electrode units 33' of the electrode sheet 13'; or stopping applying the alternating electric signal to all electrode units 33' in the column group where the electrode units 33' in the electrode sheet 13' that exceed the preset temperature threshold are located.

[0415] Furthermore, in the case of stopping applying the alternating electric signal to all the electrode units 33' of the column group where the electrode unit 33' exceeding the preset temperature threshold in the electrode sheet 13' is located, the alternating electric signal continues to be applied to the electrode units 33' of other column groups in the electrode sheet 13'. The intensity of the alternating electric signal applied to the electrode units 33' of other column groups in the electrode sheet 13' is adjustable. For example, all the electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in different columns from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the alternating electric signals applied to different column groups may be the same or different, for example, the voltage or current amplitude of the alternating electric signal applied to the column group that is closer to the preset temperature threshold but does not exceed the preset temperature threshold is smaller, and vice versa.

[0416] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242' specifically includes:

[0417] Step 2422': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33' of the electrode sheet 13', wherein the first preset temperature is less than the preset temperature threshold.

[0418] In step 2422', the magnitude of increase in electric field strength corresponding to each column group whose alternating electric signal strength is increased may be the same or different, that is, adjustable. For example, the voltage or current amplitude of the alternating electric signal applied by the column group with the lower maximum temperature is greater, and vice versa.

[0419] Step 2423': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if there is at least one electrode unit 33' in the electrode sheet 13' where the temperature exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal of the electrode unit 33' currently applied to the electrode sheet 13' is maintained unchanged.

[0420] In step 2423', maintaining the strength of the alternating electric signal currently applied to the electrode unit 33' unchanged specifically includes: maintaining the strength of the alternating electric signal currently applied to the first target column group unchanged, wherein the first target column group is a column group where the temperature at the electrode unit 33' exceeds the first preset temperature and is less than the preset temperature threshold. In other words, only the voltage or current amplitude of the alternating electric signal corresponding to the column group whose temperature exceeds the first preset temperature and is less than the preset temperature threshold can be maintained, and the voltage or current amplitude of the alternating electric signal corresponding to the remaining column groups can still be adjusted according to the temperature of the corresponding column group.

[0421] Step 2424': When the temperatures at all electrode units 33' in the electrode sheet 13' do not exceed the preset temperature threshold, if there is at least one electrode unit 33' in the electrode sheet 13' where the temperature exceeds the second preset temperature and is less than the preset temperature threshold, then reduce the intensity of the alternating electric signal applied to the electrode unit 33' of the electrode sheet 13'.

[0422] In step 2424', reducing the strength of the alternating electric signal applied to the electrode unit 33' specifically includes: reducing the strength of the alternating electric signal applied to the electrode unit 33' of the second target column group, wherein the second target column group is a column group where the temperature at the electrode unit 33' exceeds the second preset temperature and is less than the preset temperature threshold. That is, only the amplitude of the voltage or current of the alternating electric signal corresponding to the column group whose temperature exceeds the second preset temperature and is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, and the amplitude of the voltage or current of the alternating electric signal corresponding to the remaining column groups can still be adjusted according to the temperature of the corresponding column group, such as maintained or increased.

[0423] Exemplarily, when the temperature detection signal is much lower than a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitudes of the alternating electric signal applied to different column groups may be the same or different, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged. When the temperature detection signal approaches a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that keeps the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that reduces the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitude of the alternating electric signal applied to different column groups may be the same or different.

[0424] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242' specifically includes:

[0425] Step 2425 ′: When the temperature at at least one electrode unit 33 ′ exceeds a preset temperature threshold, determine the number of over-temperature column groups.

[0426] Step 2426 ′: when the number of over-temperature column groups exceeds a preset number threshold, stop applying the alternating electrical signal to all electrode units 33 ′ of the electrode sheet 13 ′.

[0427] Step 2427 ′: when the number of over-temperature column groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 ′ in the column group where the electrode units 33 ′ exceeding the preset temperature threshold in the electrode sheet 13 ′ are located.

[0428] Furthermore, in the case of stopping applying the alternating electric signal to all the electrode units 33' of the column group where the electrode unit 33' exceeding the preset temperature threshold in the electrode sheet 13' is located, the alternating electric signal continues to be applied to the electrode units 33' of other column groups in the electrode sheet 13'. The intensity of the alternating electric signal applied to the electrode units 33' of other column groups in the electrode sheet 13' is adjustable. For example, all the electrode units 33' in the electrode sheet 13' whose temperature detection signal does not exceed the preset temperature threshold and are in different columns from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the alternating electric signals applied to different column groups may be the same or different, for example, the voltage or current amplitude of the alternating electric signal applied to the column group that is closer to the preset temperature threshold but does not exceed the preset temperature threshold is smaller, and vice versa.

[0429] Step 2428': When the number of over-temperature column groups does not exceed the preset number threshold, if the temperature at each electrode unit 33' in the non-over-temperature column group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33' of the non-over-temperature column group, wherein the first preset temperature is less than the preset temperature threshold.

[0430] In step 2428', the magnitude of the electric field strength increase corresponding to each column group whose alternating electric signal strength is increased may be the same or different, that is, adjustable. For example, the voltage or current amplitude of the alternating electric signal applied by the column group with the lower maximum temperature is greater, and vice versa.

[0431] Step 2429': When the number of over-temperature column groups does not exceed the preset number threshold, if there is at least one electrode unit 33' in the non-over-temperature column group where the temperature exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal currently applied to the electrode unit 33' of the non-over-temperature column group remains unchanged.

[0432] In step 2429', maintaining the strength of the alternating electric signal currently applied to the electrode unit 33' unchanged specifically includes: maintaining the strength of the alternating electric signal currently applied to the first target column group unchanged, wherein the first target column group is a column group where the temperature at the electrode unit 33' exceeds the first preset temperature and is less than the preset temperature threshold. In other words, only the amplitude of the voltage or current of the alternating electric signal corresponding to the column group whose temperature exceeds the first preset temperature and is less than the preset temperature threshold can be maintained, and the amplitude of the voltage or current of the alternating electric signal corresponding to the remaining column groups can still be adjusted according to the temperature of the corresponding column group.

[0433] Step 2430': When the number of over-temperature column groups does not exceed the preset number threshold, if there is at least one electrode unit 33' in the non-over-temperature column group where the temperature exceeds the second preset temperature and is less than the preset temperature threshold, then reduce the intensity of the alternating electric signal applied to the electrode unit 33' of the non-over-temperature column group, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0434] In step 2430', reducing the strength of the alternating electric signal applied to the electrode unit 33' specifically includes: reducing the strength of the alternating electric signal applied to the electrode unit 33' of the second target column group, wherein the second target column group is a column group where the temperature at the electrode unit 33' exceeds the second preset temperature and is less than the preset temperature threshold. That is, only the amplitude of the voltage or current of the alternating electric signal corresponding to the column group whose temperature exceeds the second preset temperature and is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, and the amplitude of the voltage or current of the alternating electric signal corresponding to the remaining column groups can still be adjusted according to the temperature of the corresponding column group, such as maintained or increased.

[0435] Exemplarily, when the temperature detection signal is much lower than a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitudes of the alternating electric signal applied to different column groups may be the same or different, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged. When the temperature detection signal approaches a preset temperature threshold, the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that keeps the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13' unchanged, wherein the voltage or current amplitude of the alternating electric signal applied to only some column groups may remain unchanged, or the alternating electric signal continues to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that reduces the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33' of the electrode sheet 13', wherein the voltage or current amplitude of the alternating electric signal applied to different column groups may be the same or different.

[0436] The tumor electric field treatment system 100 of this embodiment can be used Fig.11 The electrode sheet type identification method shown is used to identify the type of the electrode sheet 13'. Fig.11 , I will not go into details here.

[0437] The tumor electric field treatment system 100 of this embodiment can be used Fig. 22The signal control method for tumor electric field therapy shown in the figure combines and controls the control switch 54' and the bidirectional switch 55' electrically connected to the electrode sheet 13' to switch each electrode unit 33' of the electrode sheet 13' between applying an alternating electric signal and collecting a temperature detection signal.

[0438] Reference Fig. 22 As shown, the method includes:

[0439] Step 310': Combining and controlling the control switch 54' and the bidirectional switch 55' electrically connected to the corresponding electrode sheet 13' to apply an alternating electrical signal to each electrode unit 33' of the electrode sheet 13' and executing step 320';

[0440] Applying the alternating electric signal to each electrode unit 33 ′ of the electrode sheet 13 ′ in step 310 ′ specifically includes: simultaneously applying the same or different alternating electric signals to the electrode units 33 ′ of some or all column groups in all column groups.

[0441] Step 320': Combining and controlling the control switch 54' and the bidirectional switch 55' electrically connected to the electrode sheet 13' to collect the temperature detection signals of each electrode unit 33' of the electrode sheet 13' in a row and executing step 330';

[0442] The row-wise collection of the temperature detection signals of the electrode units 33' of the electrode sheet 13' in step 320' specifically includes: the temperature detection signals of all the electrode units 33' of some row groups or all row groups in all row groups can be sampled in sequence in the same sampling time period; or the temperature detection signals of some electrode units 33' of some row groups or all row groups in all row groups can be sampled in sequence in the same sampling time period.

[0443] Step 330': determine the combined control mode of the control switch 54' and the bidirectional switch 55' electrically connected to the electrode sheet 13' according to the collected temperature detection signal and execute step 340';

[0444] Step 340 ′: controlling the working state of each electrode unit 33 ′ of the electrode sheet 13 ′ according to the determined combined control mode of the control switch 54 ′ and the bidirectional switch 55 ′.

[0445] The working state of each electrode unit 33' of the electrode sheet 13' in step 340' includes: stopping applying the alternating electric signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating electric signal. Continuing to apply the alternating electric signal includes: continuing to apply the alternating electric signal in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged, or continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal. The manner of continuing to apply the alternating electric signal corresponding to different column groups may be the same or different.

[0446] The working state of each electrode unit 33' of the electrode sheet 13' is determined by the temperature detection signal collected by it. Each electrode unit 33' of the electrode sheet 13' is divided into different areas. Through the combination of the control switch 54' and the bidirectional switch 55', each electrode unit 33' in each area can be cyclically switched between applying an alternating electric signal and collecting a temperature detection signal. When applying an alternating electric signal, different areas can be the same or different.

[0447] The tumor electric field treatment system 100 of this embodiment can be used Fig.13 The electrode sheet temperature detection method shown in the figure detects the temperature of the electrode sheet 13'. Fig.13 , I will not go into details here.

[0448] The tumor electric field treatment system 100 of this embodiment can be used Figure 14-16 The method for applying alternating electric signals for electric field therapy of tumors shown applies alternating electric signals to the electrode sheet 13 ′. The difference is that when applying alternating electric signals, the alternating electric signals applied by different column groups may be the same or different, which will not be described in detail here.

[0449] The present application also provides a tumor electric field treatment system 100 or 100', comprising: at least one pair of the aforementioned electrode sheets 13 or 13'; an electric field generator 30 or 30', the electric field generator 30 or 30' is used to generate an alternating power supply and transmit the alternating power supply to each electrode sheet 13 or 13' through an alternating power supply line 57 or 57'; a control unit (such as a first controller 51 or 51' or a second controller 37 or 37', etc.), the control unit is used to configure and control at least one of the switching state of the switch 54 or 54' and the switching state of the switching unit (unnumbered), so as to sample the analog temperature signal detected by the corresponding temperature detection unit 35 or 35' in each row group based on the corresponding temperature sampling point (unnumbered), or control the electrode unit 33 or 33' of at least one column group to be applied with an alternating electric signal based on the alternating power supply line 57 or 57'.

[0450] The present application also provides a tumor treatment device (not shown), comprising: the aforementioned tumor electric field treatment system 100 or 100 ′.

[0451] The present application also provides a computer-readable storage medium having a computer program stored thereon. When the computer program is executed by a processor, the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method is implemented.

[0452] The present application also provides an adapter 20 or 20' for tumor electric field therapy, including a first memory (not shown) and a first controller 51 or 51', wherein the first memory (not shown) stores a computer program, and when the computer program is executed by the first controller 51 or 51', it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0453] The present application also provides an electric field generator 30 or 30' for tumor electric field therapy, including a second memory (not shown) and a second controller 37 or 37'. The second memory (not shown) stores a computer program. When the computer program is executed by the second controller 37 or 37', it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0454] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, each of which includes a plurality of electrode units and a plurality of temperature detection units, each of which can apply an alternating electrical signal, and each of which is provided corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein: The plurality of electrode units are configured into at least two row groups and at least two column groups, the grounding ends of the temperature detection units in each row group are commonly connected to the grounding pin through a control switch, and the signal ends of the temperature detection units in each column group are respectively short-circuited with the corresponding electrode units and then commonly connected to the switching unit through a dual-purpose signal line; The switching unit is configured to switch the dual-purpose signal line to be connected to the temperature sampling point or the alternating power line so that In the case where the dual-purpose signal line is connected to the temperature sampling point, the switch state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point; In a case where the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to the electrode units of at least one column group based on the alternating power line.

2. The tumor electric field treatment system according to claim 1, characterized in that: The switching unit is further configured to switch the dual-purpose signal line corresponding to each column group to be connected to the corresponding temperature sampling point, so that the analog temperature signal detected by each temperature detection unit in each column group is sampled respectively according to the switch state of the control switch.

3. The tumor electric field treatment system according to claim 1, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the column groups to be simultaneously connected to corresponding temperature sampling points, so that the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on the corresponding temperature sampling points according to the switch state of the control switch.

4. The tumor electric field treatment system according to any one of claims 1 to 3, characterized in that: The switching unit includes at least two bidirectional switches, a first end of each of the bidirectional switches is connected to the dual-purpose signal line corresponding to each of the column groups, a second end of each of the bidirectional switches is simultaneously connected to the alternating power line, and a third end of each of the bidirectional switches is connected to the temperature sampling point of the corresponding column group.

5. The tumor electric field treatment system according to claim 4, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to each of the column groups to be connected to the alternating power lines, so that the electrode units of each of the column groups are simultaneously applied with the alternating electrical signals based on the alternating power lines.

6. The tumor electric field treatment system according to claim 4, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the column groups to be connected to the alternating power line at the same time, so that the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

7. The tumor electric field treatment system according to claim 4, characterized in that: The intensity of the alternating electric signal output by the alternating power line is adjustable.

8. The tumor electric field treatment system according to any one of claims 1 to 3, characterized in that: The switching unit includes at least two bidirectional switches, a first end of each of the bidirectional switches is connected to a dual-purpose signal line corresponding to each of the column groups, a second end of each of the bidirectional switches is connected to a different alternating power line, and a third end of each of the bidirectional switches is connected to a temperature sampling point of the corresponding column group.

9. The tumor electric field treatment system according to claim 8, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two column groups to connect to different alternating power lines, so that the alternating electrical signals are applied to the electrode units of each column group based on different alternating power lines.

10. The tumor electric field treatment system according to claim 8, characterized in that: The strength of the alternating electric signals output by different alternating power lines can be adjusted respectively.

11. The tumor electric field treatment system according to claim 1, characterized in that: Each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

12. The tumor electric field treatment system according to claim 1, characterized in that: Each of the temperature sampling points is connected to a DC power supply via a corresponding voltage dividing resistor.

13. The tumor electric field treatment system according to claim 12, characterized in that: It also includes an adapter, wherein the control switch, the switching unit and the voltage dividing resistor are respectively arranged in the adapter.

14. The tumor electric field treatment system according to claim 13, characterized in that: The adapter includes a first controller and an ADC unit, wherein the ADC unit is connected to each of the temperature sampling points so as to sample the analog temperature signal through each of the temperature sampling points, and the first controller is connected to the ADC unit so as to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

15. The tumor electric field treatment system according to claim 14, characterized in that: The first controller is further configured to configure a switch state of the control switch.

16. The tumor electric field treatment system according to claim 14, characterized in that: The first controller is further configured to configure a switching state of a bidirectional switch in the switching unit.

17. The tumor electric field treatment system according to claim 1, characterized in that: Also included is an electric field generator configured to output the alternating electric signal through the alternating power line.

18. The tumor electric field treatment system according to claim 17, characterized in that: The electric field generator includes a second controller and an AC signal generator. The second controller is connected to the AC signal generator. The second controller is configured to control the AC signal generator to adjust the strength of the alternating electric signal output by the alternating power line.

19. The tumor electric field treatment system according to claim 18, characterized in that: The electric field generator is further configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

20. The tumor electric field treatment system according to claim 18, characterized in that: The electric field generator further includes a power switch, which is disposed between the AC signal generator and the switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

21. The tumor electric field treatment system according to claim 18, characterized in that: The second controller is further configured to configure a switching state of the control switch.

22. The tumor electric field treatment system according to claim 18, characterized in that: The second controller is further configured to configure a switching state of the bidirectional switch in the switching unit.

23. An electrode sheet, characterized in that: Applied to a tumor electric field treatment system, the tumor electric field treatment system comprises a switching unit, and the electrode sheet comprises: substrate; A plurality of electrode units and a plurality of temperature detection units are arranged on the substrate, each of the electrode units can apply an alternating electrical signal, and each of the temperature detection units is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein: The plurality of electrode units are configured into at least two row groups and at least two column groups; The grounding terminals of the temperature detection units in each row group are connected to the grounding pin via a control switch; After the signal ends of the temperature detection units in each of the column groups are short-circuited with the corresponding electrode units, they are connected to the switching unit through a dual-purpose signal line, so that the dual-purpose signal line is switched by the switching unit to be connected to the temperature sampling point or the alternating power line; In the case where the dual-purpose signal line is connected to the temperature sampling point, the switch state of the control switch is configured so that the analog temperature signal detected by the corresponding temperature detection unit in each row group is sampled based on the temperature sampling point; In a case where the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to the electrode units of at least one column group based on the alternating power line.

24. The electrode sheet according to claim 23, characterized in that: In the case that the dual-purpose signal lines corresponding to each column group are respectively connected to the corresponding temperature sampling points, the analog temperature signals detected by the temperature detection units in each column group are respectively sampled by configuring the switch state of the control switch.

25. The electrode sheet according to claim 23, characterized in that: When the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to corresponding temperature sampling points, the analog temperature signals detected by the corresponding temperature detection units in each of the row groups are sampled based on corresponding temperature sampling points by configuring the switch states of the control switches.

26. The electrode sheet according to claim 23, characterized in that: In the case that the dual-purpose signal lines corresponding to each of the column groups are respectively connected to the alternating power lines, the electrode units of each of the column groups are simultaneously applied with the alternating electrical signals based on the alternating power lines.

27. The electrode sheet according to claim 23, characterized in that: In the case that the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the alternating power line, the electrode units of at least two of the column groups are simultaneously applied with the alternating electrical signals based on the alternating power line.

28. The electrode sheet according to claim 23, characterized in that: The intensity of the alternating electric signal output by the alternating power line is adjustable.

29. The electrode sheet according to claim 23, characterized in that: In the case that the dual-purpose signal lines corresponding to the at least two column groups are connected to different alternating power lines, the alternating electrical signals are applied to the electrode units of each column group based on different alternating power lines.

30. The electrode sheet according to claim 29, characterized in that: The strength of the alternating electric signals output by different alternating power lines can be adjusted respectively.

31. The electrode sheet according to claim 23, characterized in that: Each of the temperature detection units includes a temperature sensor and a diode, the temperature sensor has a signal terminal and a ground terminal, the diode has an anode and a cathode, the anode of the diode is connected to the ground terminal of the temperature sensor, the cathode of the diode serves as the ground terminal of the temperature detection unit, and the signal terminal of the temperature sensor serves as the signal terminal of the temperature detection unit.

32. The electrode sheet according to claim 23, characterized in that: Each of the temperature sampling points is connected to a DC power supply via a corresponding voltage dividing resistor.

33. The electrode sheet according to any one of claims 23 to 32, characterized in that: Each of the electrode units is provided with a through hole, and the through hole is suitable for accommodating the temperature detection unit.

34. The electrode sheet according to any one of claims 23 to 32, characterized in that: The plurality of electrode units and the plurality of temperature detection units are arranged roughly in an array in terms of spatial arrangement, and the plurality of electrode units and the plurality of temperature detection units are arranged in multiple rows and columns in terms of circuit connection.

35. The electrode sheet according to claim 34, characterized in that: The number of the plurality of electrode units and the number of the plurality of temperature detection units are both 20, and they are arranged in four rows and five columns in terms of circuit connection.

36. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets according to any one of claims 23-35; An electric field generator, the electric field generator is used to generate an alternating power source, and transmit the alternating power source to each of the electrode sheets through the alternating power source line; A control unit, the control unit is used to configure at least one of the switching state of the control switch and the switching state of the switching unit, so as to sample the analog temperature signal detected by the corresponding temperature detection unit in each of the row groups based on the corresponding temperature sampling point, or to control the electrode unit of at least one of the column groups to be applied with the alternating electrical signal based on the alternating power line.

37. A tumor treatment device, characterized in that: include: A tumor electric field therapy system according to any one of claims 1-22, or a tumor electric field therapy system according to claim 36.

38. A method for detecting electrode temperature, characterized in that: Applied to the tumor treatment field system according to any one of claims 1 to 22 or to the tumor treatment field system according to claim 36, the method comprising: Controlling the switching unit so that the dual-purpose signal line corresponding to at least one column group in the corresponding electrode sheet is connected to the corresponding temperature sampling point; The control switch corresponding to each row group is controlled so as to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

39. The method according to claim 38, characterized in that When the dual-purpose signal lines corresponding to each column group are respectively connected to the corresponding temperature sampling points, the control switches corresponding to each row group are controlled, including: The control switches corresponding to each row group are controlled to be closed in sequence, so as to respectively sample the analog temperature signals of each electrode unit in each column group.

40. The method according to claim 38, characterized in that When the dual-purpose signal lines corresponding to at least two of the column groups are simultaneously connected to the corresponding temperature sampling points, the control switches corresponding to each of the row groups are controlled, including: The control switches corresponding to each row group are controlled to be closed in sequence, so as to respectively sample the analog temperature signals of the corresponding electrode units in each row group.

41. A method for detecting abnormality of an electrode sheet, characterized in that: A preset threshold is preset in the adapter or the electric field generator, and the method includes: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method described in any one of claims 38 to 40; Whether the electrode sheet is abnormal is determined according to the temperature detection signal.

42. The method according to claim 41, characterized in that Judging whether the electrode sheet is abnormal according to the temperature detection signal includes: When it is determined according to the temperature detection signal that any one electrode unit in the corresponding electrode sheet is abnormal or fails, the electrode sheet is determined to be unqualified.

43. The method according to claim 41, characterized in that Judging whether the electrode sheet is abnormal according to the temperature detection signal includes: In the case where it is determined according to the temperature detection signal that an abnormal or faulty electrode unit exists in the corresponding electrode sheet, determining the number of the abnormal or faulty electrode units; When the number of abnormal or faulty electrode units reaches a preset threshold, it is determined that the electrode sheet needs to be replaced.

44. The method according to claim 41, characterized in that Judging whether the electrode sheet is abnormal according to the temperature detection signal includes: Comparing the temperature of each electrode unit in the corresponding electrode sheet with a preset temperature threshold according to the temperature detection signal; Whether the temperature of the electrode sheet is abnormal is determined based on the comparison result.

45. The method according to claim 44, characterized in that Judging whether the temperature of the electrode sheet is abnormal based on the comparison result includes: When the temperature at any one electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet is abnormal.

46. ​​A control method for a tumor electric field treatment system, characterized in that: The adapter or the electric field generator is preset with a preset temperature threshold, a preset quantity threshold, a first preset temperature and a second preset temperature, and the method includes: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method described in any one of claims 38 to 40; The intensity of the alternating electric signal applied to the electrode unit is controlled according to the temperature detection signal.

47. The method according to claim 46, characterized in that Controlling the intensity of the alternating electric signal applied to the electrode unit according to the temperature detection signal includes: Comparing the temperature of each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; The intensity of the alternating electric signal is controlled according to the comparison result.

48. The method according to claim 47, characterized in that Controlling the intensity of the alternating electric signal according to the comparison result includes: When the temperature at at least one electrode unit exceeds a preset temperature threshold, the application of the alternating electric signal to the electrode units of the electrode sheet is stopped.

49. The method according to claim 48, characterized in that Stopping applying the alternating electrical signal to the electrode unit of the electrode sheet comprises: Stop applying the alternating electric signal to all electrode units of the electrode sheet; or Stop applying the alternating electric signal to all electrode units in the column group where the electrode unit whose temperature exceeds the preset threshold value in the electrode sheet is located.

50. The method of claim 47, wherein: Controlling the intensity of the alternating electric signal according to the comparison result includes: determining the number of over-temperature column groups when the temperature at at least one electrode unit exceeds a preset temperature threshold; When the number of the over-temperature column groups exceeds a preset number threshold, stopping applying the alternating electric signal to all electrode units of the electrode sheet; When the number of the over-temperature column groups does not exceed the preset number threshold, the application of the alternating electric signal to all the electrode units in the column group where the electrode units exceeding the preset temperature threshold in the electrode sheet are located is stopped.

51. The method according to claim 49 or 50, characterized in that In the case of stopping applying the alternating electrical signal to all electrode units in the column group where the electrode unit in the electrode sheet that exceeds the preset temperature threshold is located, the method further includes: The alternating electric signal is continuously applied to the electrode units of other column groups in the electrode sheet.

52. The method according to claim 51, characterized in that The intensity of the alternating electric signal applied to the electrode units of other column groups in the electrode sheet is adjustable.

53. The method according to claim 51, characterized in that The intensity of the alternating electric signal applied to the electrode units of each column group in the other column groups is adjustable.

54. The method according to claim 47, characterized in that Controlling the intensity of the alternating electric signal according to the comparison result includes: When the temperature at all electrode units in the electrode sheet does not exceed a preset temperature threshold, if the temperature at all electrode units in the electrode sheet does not exceed a first preset temperature, the intensity of the alternating electric signal applied to the electrode units of the electrode sheet is increased, wherein the first preset temperature is less than the preset temperature threshold.

55. The method according to claim 54, characterized in that When the temperature of all electrode units in the electrode sheet does not exceed a preset temperature threshold, the method further includes: If the temperature of at least one electrode unit in the electrode sheet exceeds the first preset temperature and is less than a preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit of the electrode sheet is kept unchanged.

56. The method according to claim 55, characterized in that When the temperature of all electrode units in the electrode sheet does not exceed a preset temperature threshold, the method further includes: If the temperature of at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than a preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit of the electrode sheet is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

57. The method according to claim 50, characterized in that When the number of the over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature at each electrode unit in the non-overtemperature column group does not exceed a first preset temperature, the intensity of the alternating electric signal applied to the electrode unit of the non-overtemperature column group is increased, wherein the first preset temperature is less than the preset temperature threshold.

58. The method according to claim 57, characterized in that When the number of the over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature of at least one electrode unit in the non-overtemperature column group exceeds the first preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit of the non-overtemperature column group is kept unchanged.

59. The method according to claim 58, characterized in that When the number of the over-temperature column groups does not exceed a preset number threshold, the method further includes: If the temperature of at least one electrode unit in the non-overtemperature column group exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit of the non-overtemperature column group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

60. The method according to claim 54 or 57, characterized in that The electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased have the same increase range.

61. The method according to claim 54 or 57, characterized in that The increase ranges of the electric field strengths corresponding to the column groups whose alternating electric signal strengths are increased are different from each other.

62. The method according to claim 55 or 58, characterized in that Maintaining the strength of the alternating electrical signal currently applied to the electrode unit unchanged, including: The intensity of the alternating electric signal currently applied to the first target column group is kept unchanged, wherein the first target column group is a column group where the temperature of the electrode unit exceeds the first preset temperature and is less than the preset temperature threshold.

63. The method according to claim 56 or 59, characterized in that Reducing the intensity of the alternating electric signal applied to the electrode unit, including: The intensity of the alternating electric signal applied to the electrode unit of the second target column group is reduced, wherein the second target column group is a column group where the temperature of the electrode unit exceeds the second preset temperature and is less than the preset temperature threshold.

64. A method for identifying electrode sheet type, characterized in that: The method comprises: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method described in any one of claims 38 to 40; The type of the electrode sheet is identified according to the temperature detection signal.

65. A computer-readable storage medium, characterized in that A computer program is stored thereon, and when the computer program is executed by the processor, The electrode sheet temperature detection method according to any one of claims 38 to 40; or The electrode sheet abnormality detection method according to any one of claims 41 to 45; or A method for controlling a tumor electric field treatment system according to any one of claims 46 to 63; or The electrode sheet type identification method according to claim 64.

66. A tumor electric field therapy adapter, comprising a first memory and a first controller, characterized in that: The first memory stores a computer program, which, when executed by the first controller, implements The electrode sheet temperature detection method according to any one of claims 38 to 40; or The electrode sheet abnormality detection method according to any one of claims 41 to 45; or A method for controlling a tumor electric field treatment system according to any one of claims 46 to 63; or The electrode sheet type identification method according to claim 64.

67. An electric field generator for electric field therapy of tumors, comprising a second memory and a second controller, characterized in that: The second memory stores a computer program, which, when executed by the second controller, implements The electrode sheet temperature detection method according to any one of claims 38 to 40; or The electrode sheet abnormality detection method according to any one of claims 41 to 45; or A method for controlling a tumor electric field treatment system according to any one of claims 46 to 63; or The electrode sheet type identification method according to claim 64.

Images