Behavioristics combination device for evaluating motion function of animal with brain injury

Abstract

The invention belongs to the technical field of behavioral experiments, and discloses a behavioral combination device for evaluating the motor function of a brain injury animal. The behavioral combination device comprises a main body structure and a functional structure, the main body structure is provided with an experiment cavity, the top of the experiment cavity is open, two opposite side walls are provided with at least two mounting jacks, and the functional structure comprises at least two of a suspension fiber test module, a rotating rod test module, a balance beam module, a climbing rod module and an elevated grid module. According to the behavioral combination device, different parts are assembled and combined to form a device required for different behavioral tests, so that the purpose that a single device meets various test functions is achieved, and the purposes of improving the use experience of the device, improving the space utilization rate, reducing the space occupation and improving the resource utilization rate are achieved.

Description

Technical Field

[0001] The invention relates to the technical field of behavioral experiments, and in particular to a behavioral combination device for evaluating the motor function of brain-injured animals. Background Art

[0002] The experimental method for evaluating the motor function of small animals is usually to evaluate the performance of small animals (such as mice or rats) in different motor tasks through a series of standardized experiments, so as to understand the functional state of their nervous system, especially the ability of motor coordination, balance, strength, endurance, etc. These experiments are widely used in the research of neuroscience, pharmacology and rehabilitation medicine. Several common behavioral experiments include open-loop maze (also known as open field test or open field test), hanging test, rotating rod test, metal mesh test, balance beam test, horizontal bar crawling test, etc. Since the above experimental methods have different focuses, some focus on evaluating motor endurance and coordination, and some focus on muscle strength or nervous system function, these methods are often used in combination to provide multi-dimensional information. In scientific research activities, researchers often design multiple behavioral tests at the same time to obtain comprehensive motor function data from fewer experimental animals, so as to better understand the disease state and its physiological characteristics in animal models.

[0003] The disadvantages of the current mainstream animal behavior devices are that they have a single function, occupy a large space, are complex to assemble, and are difficult to store. Specifically, the current motor behavior devices are mainly designed and manufactured for a single behavioral test, and it is difficult to use them for other motor behavior tests; therefore, in scientific research activities, if it involves conducting multiple different behavioral tests, behavioral testing equipment of different volumes and specifications are often required. In addition, the size and shape of existing equipment vary according to test requirements, but they generally have the problem of being bulky and occupying a lot of space, which can easily cause difficulties in use and storage. Especially in barrier environments, high-level clean laboratories and other environments, the access to experimental equipment is strictly restricted, and there is a huge construction and maintenance behind the workspace of each unit. Therefore, using a large amount of space to hoard experimental equipment often causes a certain degree of resource waste and inefficiency. Summary of the invention

[0004] The purpose of the present invention is to provide a behavioral combination device for evaluating the motor function of brain-injured animals. The behavioral combination device is formed by assembling different components to form a device that can be used for different behavioral tests, thereby achieving the purpose of a single device meeting multiple test functions, thereby improving the user experience of the device, increasing space utilization and reducing space occupancy, and improving resource utilization.

[0005] To achieve this object, the present invention adopts the following technical solutions:

[0006] The present invention discloses a behavioral combination device for evaluating the motor function of brain-injured animals, comprising: a main structure, wherein the main structure has an experimental cavity, the top of the experimental cavity is open, and at least two installation sockets are provided on two oppositely arranged side walls; a functional structure, wherein the functional structure comprises at least two of a hanging wire test module, a rotating rod test module, a balance beam module, a climbing pole module and an elevated grid module; wherein: the hanging wire test module, the rotating rod test module, the balance beam module and the climbing pole module are detachably mounted on the installation sockets; and the elevated grid module is detachably mounted on the open end of the experimental cavity.

[0007] In some embodiments, the main structure includes a cylindrical structure and a base, and the base is detachably connected to the bottom of the cylindrical structure.

[0008] In some specific embodiments, the cylindrical structure includes a plurality of splicing plates spliced ​​in sequence, and the splicing plates are any one of transparent organic glass, opaque colored organic glass, stainless steel plates, and aluminum alloy plates.

[0009] In some embodiments, the suspension wire test module includes a suspension wire body and a mounting assembly connected to two ends of the suspension wire body, and the mounting assembly is detachably matched with the mounting socket.

[0010] In some specific embodiments, the mounting socket includes a circular hole; the mounting assembly includes: a mounting nut, the mounting nut is installed in the mounting socket; and a mounting bolt, the mounting bolt is connected to the end of the suspension wire body and is threadedly connected to the mounting nut.

[0011] In some embodiments, the mounting socket includes a circular hole, and the rotating rod test module includes: a rotating rod, the rotating rod includes a main body and a rotating shaft part inserted at both ends of the main body, and the two rotating shaft parts are rotatably installed in the mounting socket; a driving member, the driving member is installed on the outer wall of the main structure and is connected to one of the rotating shaft parts.

[0012] In some embodiments, the balance beam module includes a plurality of columns spliced ​​in sequence, and the balance beam module is inserted into the mounting socket; among two adjacent columns, one of the columns is provided with a splicing groove, and the other column is provided with a splicing protrusion that cooperates with the splicing groove.

[0013] In some embodiments, the mounting socket comprises a rectangular hole; the climbing pole module comprises a plurality of climbing pole units spliced ​​in sequence, each of the climbing pole units comprises two support plates arranged at intervals and a plurality of support poles connected between the two support plates, and among two adjacent climbing pole units, a splicing tenon is provided on the support plate of one of the climbing pole units, and a splicing tenon groove cooperating with the splicing tenon is provided on the support plate of the other climbing pole unit.

[0014] In some embodiments, the elevated grid module comprises a metal mesh fixed to the open end of the experimental chamber by fixing tape.

[0015] In some specific embodiments, the mesh of the metal mesh is a square hole with a side length of 1.0 cm-1.5 cm.

[0016] The behavioral combination device for evaluating the motor function of brain-injured animals of the present invention has beneficial effects: the diversification of the functions of the behavioral combination device can be achieved by combining and building different functional structures and main structures, avoiding the need to purchase independent devices for each behavioral test, and reducing the burden on workspace and storage space. The behavioral combination device can complete the change of the device function with a relatively small workload, and can be used for six behavioral tests such as an open-loop maze (also known as an open field test or an open field experiment), a hanging test, a rotating rod test, an elevated grid test, a balance beam test, and a crossbar crawling test, which helps to improve space utilization, work efficiency, and the user experience of operators. In addition, the functional structures can all be stored in the main structure, which greatly improves the space utilization in storage. Compared with the separate equipment required to realize the function, the space occupancy rate of the storage required has a more obvious decrease.

[0017] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic diagram of the decomposed structure of the main structure of an embodiment of the present invention;

[0019] Figure 2 is a structural schematic diagram of a hanging wire test module according to an embodiment of the present invention;

[0020] Figure 3 is a schematic structural diagram of a rotating rod test module according to an embodiment of the present invention;

[0021] Figure 4 is a structural schematic diagram of a balance beam module according to an embodiment of the present invention;

[0022] Figure 5 is a schematic structural diagram of a column according to an embodiment of the present invention;

[0023] Figure 6 is a structural schematic diagram of a pole climbing module according to an embodiment of the present invention;

[0024] Figure 7 is a schematic structural diagram of a pole climbing unit according to an embodiment of the present invention;

[0025] Figure 8 is a schematic structural diagram of an elevated grid module according to an embodiment of the present invention;

[0026] Fig. 9 is a schematic structural diagram of an elevated grid module installed on the main structure of an embodiment of the present invention;

[0027] Fig.10 It is a structural schematic diagram of a climbing pole module installed on the main structure of an embodiment of the present invention.

[0028] Reference numerals:

[0029] 100, main structure; 101, experimental chamber; 102, installation jack; 110, cylindrical structure; 120, base;

[0030] 200, suspension wire test module; 210, suspension wire body; 220, mounting assembly; 221, mounting nut; 222, mounting bolt;

[0031] 300, rotating rod test module; 310, rotating rod; 311, main body; 312, rotating shaft; 320, driving member;

[0032] 400, balance beam module; 410, column;

[0033] 500, pole climbing module; 510, pole climbing unit; 511, support plate; 512, support pole;

[0034] 600, elevated grid module. DETAILED DESCRIPTION

[0035] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only parts related to the present invention, rather than all structures, are shown in the accompanying drawings.

[0036] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0037] In the description of this embodiment, the terms "upper", "lower", "left", "right", "front", "rear" and other directions or positional relationships are based on the directions or positional relationships shown in the drawings, and are only for the convenience of description and simplification of operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operate in a specific direction, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0038] The present invention discloses a behavioral combination device for evaluating motor function of brain-injured animals (hereinafter referred to as the behavioral combination device), Figure 1-Figure 7As shown, the behavioral combination device includes a main structure 100 and a functional structure. The main structure 100 has an experimental chamber 101. The top of the experimental chamber 101 is open, and at least two types of installation sockets 102 are provided on two opposite side walls. The functional structure includes at least two of a hanging wire test module 200, a rotating rod test module 300, a balance beam module 400, a climbing pole module 500, and an elevated grid module 600. The hanging wire test module 200, the rotating rod test module 300, the balance beam module 400, and the climbing pole module 500 are detachably mounted on the installation socket 102; the elevated grid module 600 is detachably mounted on the open end of the experimental chamber 101. It is understandable that, since the top of the experimental chamber 101 is open, and at least two installation sockets 102 are provided on the two oppositely arranged side walls, in the actual working process, any one of the hanging wire test module 200, the rotating rod test module 300, the balance beam module 400, and the climbing pole module 500 can be installed in the experimental chamber 101, and the elevated grid module 600 can also be installed at the open end of the experimental chamber 101. This combination and construction of different functional structures can realize the diversification of the functions of the behavioral combination device of this embodiment, avoid the purchase of independent devices for each behavioral test, and reduce the burden on the workspace and storage space. The behavioral combination device of this embodiment can complete the change of the device function with a relatively small workload, and can be used for six behavioral tests such as open-loop maze (also known as open field test or open field experiment), suspension test, rotating rod test, elevated grid test, balance beam test, and horizontal bar crawling test, which helps to improve space utilization, work efficiency, and operator experience. In addition, all functional structures can be stored in the main structure 100, which greatly improves the space utilization rate in storage. Compared with the space required for storage and the space occupied by the separate equipment required to realize the function, the space occupied by the storage is significantly reduced.

[0039] refer to Figure 1 As shown, the main structure 100 includes a cylindrical structure 110 and a base 120, and the base 120 is detachably connected to the bottom of the cylindrical structure 110. It can be understood that by splitting the main structure 100 into a detachable base 120 and a cylindrical structure 110, it is convenient to install the main structure 100 on other experimental devices according to actual needs, so that the experimental chamber 101 is connected or separated from other experimental devices, which is conducive to further improving the compatibility of the behavioral combination device. It should be noted that the detachable connection method of the cylindrical structure 110 and the base 120 can be adopted in various ways according to actual needs, such as tape bonding, mortise and tenon structure connection, etc., and the connection method of the cylindrical structure 110 and the base 120 is not specifically limited here.

[0040] Optionally, the tubular structure 110 includes a plurality of splicing plates spliced ​​in sequence. It is understandable that the tubular structure 110 includes a plurality of splicing plates spliced ​​in sequence, and the tubular structure 110 can be split into a plurality of splicing plates for storage when not in use, further reducing the storage volume of the behavioral combination device of this embodiment. The number of splicing plates in this embodiment is four, each of which is rectangular, and has a width of 45cm-65cm and a length of 50cm-80cm. Of course, in other embodiments of the present invention, the shape and related dimensions of the splicing plates can be adjusted according to actual needs and are not limited to the above description. In addition, two adjacent splicing plates can be connected by methods such as tape bonding, mortise and tenon structure connection, and no specific restrictions are imposed on the connection method of the two adjacent splicing plates.

[0041] Optionally, the splicing plate is any one of transparent organic glass, opaque colored organic glass, stainless steel plate, and aluminum alloy plate. Of course, in other embodiments of the present invention, the splicing plate can also be selected from other materials according to actual needs.

[0042] refer to Figure 1 As shown, the mounting socket 102 on the main structure 100 includes a circular hole and a square hole, wherein the diameter of the circular hole is 0.5cm-2cm, and the distance from the bottom of the main structure 100 is 45cm; the size of the rectangular hole is 5cm×10cm, and the distance from the bottom of the main structure 100 is 25-35cm.

[0043] refer to Figure 2 As shown, the hanging wire test module 200 includes a hanging wire body 210 and a mounting assembly 220 connected to both ends of the hanging wire body 210, and the mounting assembly 220 is detachably matched with the circular hole. It can be understood that in the actual installation process, it is only necessary to install the two mounting assemblies 220 into the two circular holes respectively to complete the installation, which is very convenient to operate and facilitates the installation and removal of the hanging wire test module 200. In order to improve the installation stability of the hanging wire test module 200, the phenomenon of the installation assembly 220 falling can also be avoided by bonding the tape on the outer wall of the mounting assembly 220 and the main structure 100.

[0044] Optionally, the mounting assembly 220 includes a mounting nut 221 and a mounting bolt 222, wherein the mounting nut 221 is mounted in the circular hole, and the mounting bolt 222 is connected to the end of the suspension wire body 210 and is threadedly connected to the mounting nut 221. It is understandable that after the suspension wire test module 200 is installed, the tightness of the suspension wire body 210 can be adjusted by rotating the mounting bolt 222, thereby facilitating the suspension test.

[0045] refer to Figure 3As shown, the rotating rod test module 300 includes a rotating rod 310 and a driving member 320. The rotating rod 310 includes a main body 311 and a rotating shaft 312 plugged at both ends of the main body 311. The two rotating shafts 312 are rotatably installed in the installation socket 102. The driving member 320 is installed on the outer wall of the main structure 100 and is connected to one of the rotating shafts 312. It can be understood that in the actual installation process, the main body 311 is placed in the experimental cavity 101 and aligned with the circular hole, and then the two rotating shafts 312 are inserted into the main body 311 through the circular hole. This installation method is very convenient to operate and facilitates the experimenter to install or remove the rotating rod test module 300. Optionally, the diameter of the main body 311 is 3cm-5cm, and the length is equal to the side length of the main structure 100. The length of the two sections of the rotating shaft 312 for installation is 1-2cm, and the diameter is the same as the circular hole. The rotation speed of the driving member 320 is 10rpm-200rpm.

[0046] It should be noted that the driving member 320 can be fixed to the outer wall of the main structure 100 by means of screw connection or the like, or it can be installed by a separate bracket. The output shaft of the driving member 320 can be connected to the rotating shaft portion 312 by a connecting key, or it can be connected to the rotating shaft portion 312 by a coupling or other structure.

[0047] refer to Figure 4-Figure 5 As shown, the balance beam module 400 includes a plurality of columns 410 spliced ​​in sequence, and the balance beam module 400 is inserted into the installation socket 102. It can be understood that the balance beam module 400 is split into a plurality of columns 410, and the plurality of columns 410 are spliced ​​in sequence to form the balance beam module 400 during the assembly process, and then the balance beam module 400 is inserted into the installation socket 102. On the one hand, it is convenient to install and disassemble the balance beam module 400, and on the other hand, it is conducive to reducing the storage volume of the balance beam module 400, and further reducing the space occupancy rate of the behavioral combination device. Further optionally, the cross-section of the column 410 is square, and the side length does not exceed 2.5 cm. Of course, in other embodiments of the present invention, the cross-sectional shape and size of the main body can be adjusted according to actual needs.

[0048] Optionally, one of the two adjacent columns 410 is provided with a splicing groove (not shown in the figure), and the other column 410 is provided with a splicing protrusion (not shown in the figure) that cooperates with the splicing groove. It can be understood that the assembly of the two adjacent columns 410 is achieved by the cooperation of the splicing groove and the splicing protrusion, which, on the one hand, facilitates assembly and disassembly, and on the other hand, helps to improve the strength of the balance beam module 400, ensuring that the balance beam module 400 will not break during the balance beam test. The shape, number, size and other parameters of the splicing groove and the splicing protrusion can be selected according to actual needs, and the specific parameters of the splicing groove and the splicing protrusion are not limited here.

[0049] refer to Figure 6-Figure 7 As shown, the mounting socket 102 includes a rectangular hole; the pole climbing module 500 includes a plurality of pole climbing units 510 spliced ​​in sequence, and each pole climbing unit 510 includes two support plates 511 arranged at intervals and a plurality of support rods 512 connected between the two support plates 511. It can be understood that the pole climbing module 500 is split into a plurality of pole climbing units 510, and the plurality of pole climbing units 510 are spliced ​​in sequence to form the pole climbing module 500 during the assembly process, and then the pole climbing module 500 is inserted into the mounting socket 102. On the one hand, it is convenient to install and disassemble the pole climbing module 500, and on the other hand, it is conducive to reducing the storage volume of the pole climbing module 500, and further reducing the space occupancy rate of the behavioral combination device.

[0050] Optionally, both ends of the support rod 512 are plugged into the support plate 511. In the actual test process, different support rods 512 can be selected according to actual needs to achieve adjustable spacing between the two support plates 511, thereby further improving the compatibility of the behavioral combination device. Further optionally, the support rod 512 is a round rod with a diameter of 0.5 mm and a length of 2.5 mm.

[0051] Optionally, in two adjacent climbing pole units 510, a splicing tenon (not shown) is provided on the support plate 511 of one climbing pole unit 510, and a splicing tenon (not shown) that cooperates with the splicing tenon is provided on the support plate 511 of the other climbing pole unit 510. It can be understood that the assembly of two adjacent climbing pole units 510 is achieved through the cooperation of the splicing tenon and the splicing tenon, which, on the one hand, facilitates assembly and disassembly, and on the other hand, helps to improve the strength of the climbing pole module 500, ensuring that the climbing pole module 500 will not break during the climbing pole test. The shape, quantity, size and other parameters of the splicing tenon and the splicing tenon can be selected according to actual needs, and the specific parameters of the splicing tenon and the splicing tenon are not limited here.

[0052] refer to Figure 8 As shown, the elevated grid module 600 includes a metal mesh, which is fixed to the open end of the experimental chamber 101 by a fixing tape. Therefore, the installation and removal of the elevated grid module 600 are facilitated.

[0053] Optionally, the mesh of the metal mesh is a square hole, and the side length is 1.0 cm-1.5 cm. Of course, in other embodiments of the present invention, the mesh of the metal mesh can also be adjusted according to actual needs and is not limited to the above limitations.

[0054] Two specific experimental cases are described below:

[0055] Experimental Case 1: Experimental Case 1 in the present invention is composed of a main structure 100 and a metal mesh. A square cylindrical structure 110 is installed on a square base 120, and then the metal mesh is installed on the top of the cylindrical structure 110 (such as Fig. 9 As shown). The camera used to observe the behavior of the model animal can be installed inside the experimental chamber 101 or outside the experimental chamber 101 through an independent bracket to record the behavior of the mouse on the metal net. The mouse can then be placed on the top grid. Due to the impaired motor function of the model animal, the fine movement ability of the limbs on the affected side is reduced during the activity on the metal net, and it is easy to step on empty space; while the number of mistakes made by normal animals is significantly less than that of model animals.

[0056] Experimental Case 2: Experimental Case 2 in the present invention is composed of a main structure 100 and a pole climbing module 500. After the three pole climbing units 510 are assembled together through the mortise and tenon structure, they are inserted into the rectangular installation socket 102 of the main structure 100 (such as Fig.10 As shown, the cameras for observation are arranged at certain intervals on the side and above the main structure 100 to record the activities of the model animal on the climbing pole module 500. The activities of the animal's claws are recorded at the same time and then analyzed. One day before the experiment, the model animal was trained on how to cross the ladder. During the experiment, each test was to cross 3-5 times. The results were then recorded and analyzed, and the structure was divided into seven levels from 0 to 6: 0, completely unable; 1, obvious fall; 2, slight slip; 3, re-placement; 4, wrong placement; 5, partial placement; 6, correct placement, error score = number of errors / total number × 100.

[0057] In the description of this specification, the description with reference to the terms "some embodiments", "other embodiments", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0058] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the protection scope of the present invention. It is not necessary and impossible to list all the embodiments here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the claims of the present invention.

Claims

1. A behavioral combination device for evaluating motor function in brain-injured animals, characterized in that: include: A main structure (100), the main structure (100) having an experimental cavity (101), the top of the experimental cavity (101) being open, and at least two types of installation sockets (102) being provided on two oppositely arranged side walls; A functional structure, the functional structure comprising at least two of a hanging wire test module (200), a rotating rod test module (300), a balance beam module (400), a climbing pole module (500) and an elevated grid module (600); wherein: The hanging wire test module (200), the rotating rod test module (300), the balance beam module (400), and the climbing pole module (500) are detachably mounted on the mounting socket (102); and the elevated grid module (600) is detachably mounted on the open end of the experimental chamber (101).

2. The behavioral combination device for evaluating motor function of brain-injured animals according to claim 1, characterized in that: The main structure (100) comprises a cylindrical structure (110) and a base (120), wherein the base (120) is detachably connected to the bottom of the cylindrical structure (110).

3. The behavioral combination device for evaluating motor function of brain-injured animals according to claim 2, characterized in that: The cylindrical structure (110) comprises a plurality of splicing plates spliced ​​in sequence, wherein the splicing plates are any one of transparent organic glass, opaque colored organic glass, stainless steel plates, and aluminum alloy plates.

4. The behavioral combination device for evaluating motor function of brain-injured animals according to any one of claims 1 to 3, characterized in that: The suspension wire test module (200) comprises a suspension wire body (210) and a mounting assembly (220) connected to two ends of the suspension wire body (210); the mounting assembly (220) is detachably matched to the mounting socket (102).

5. The behavioral combination device for evaluating motor function of brain-injured animals according to claim 4, characterized in that: The mounting socket (102) comprises a circular hole; the mounting assembly (220) comprises: A mounting nut (221), wherein the mounting nut (221) is mounted in the mounting socket (102); A mounting bolt (222) is connected to the end of the suspension wire body (210) and is threadedly connected to the mounting nut (221).

6. The behavioral combination device for evaluating motor function of brain-injured animals according to any one of claims 1 to 3, characterized in that: The mounting socket (102) comprises a circular hole, and the rotating rod testing module (300) comprises: A rotating rod (310), the rotating rod (310) comprising a main body (311) and rotating shafts (312) plugged into two ends of the main body (311), the two rotating shafts (312) being rotatably mounted in the mounting socket (102); A driving member (320), wherein the driving member (320) is installed on the outer wall of the main structure (100) and is connected to one of the rotating shaft parts (312).

7. The behavioral combination device for evaluating motor function of brain-injured animals according to any one of claims 1 to 3, characterized in that: The balance beam module (400) comprises a plurality of columns (410) that are spliced ​​in sequence, and the balance beam module (400) is inserted into the installation socket (102); Of the two adjacent columns (410), one of the columns (410) is provided with a splicing groove, and the other column (410) is provided with a splicing protrusion that matches the splicing groove.

8. The behavioral combination device for evaluating motor function of brain-injured animals according to any one of claims 1 to 3, characterized in that: The mounting socket (102) comprises a rectangular hole; The pole climbing module (500) comprises a plurality of pole climbing units (510) spliced ​​in sequence, each of the pole climbing units (510) comprising two support plates (511) arranged at intervals and a plurality of support poles (512) connected between the two support plates (511); of two adjacent pole climbing units (510), a splicing tenon is provided on the support plate (511) of one of the pole climbing units (510), and a splicing tenon groove cooperating with the splicing tenon is provided on the support plate (511) of the other pole climbing unit (510).

9. The behavioral combination device for evaluating motor function of brain-injured animals according to any one of claims 1 to 3, characterized in that: The elevated grid module (600) comprises a metal mesh, which is fixed to the open end of the experimental chamber (101) by means of a fixing tape.

10. The behavioral combination device for evaluating motor function of brain-injured animals according to claim 9, characterized in that: The mesh of the metal mesh is a square hole with a side length of 1.0 cm to 1.5 cm.

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