Oral medicament for lumbar disc herniation and preparation method thereof

Abstract

The invention discloses an oral medicament for lumbar disc herniation and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following materials in parts by mass: 4 to 8 parts of black prepared aconite root, 10 to 20 parts of poria cocos, 5 to 15 parts of rhizoma atractylodis macrocephalae, 10 to 14 parts of radix paeoniae alba, 4 to 8 parts of fresh ginger, 10 to 20 parts of cortex eucommiae, 10 to 14 parts of radix dipsaci, 10 to 20 parts of herba taxilli, 10 to 14 parts of rhizoma cibotii, 4 to 8 parts of ground beeltle, 1 to 5 parts of radix notoginseng and 30 to 55 parts of honey. According to the oral medicament for lumbar disc herniation and the pills prepared by the preparation method, the uncomfortable symptoms such as waist pain, lower limb radiation pain and numbness of a patient with lumbar disc herniation can be effectively relieved, and the life quality of the patient is improved.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and in particular to an oral medicament for lumbar disc herniation and a preparation method thereof. Background Art

[0002] Lumbar disc herniation is a common spinal disease that brings great pain and inconvenience to patients. With the changes in modern lifestyles, such as long-term sitting, long-term bending over and carrying weight, the incidence of lumbar disc herniation has increased year by year.

[0003] Treatments for lumbar disc herniation mainly include surgical treatment and conservative treatment. Although surgical treatment can solve the herniation problem to a certain extent, it has disadvantages such as high risk, large trauma, and long postoperative recovery time. Conservative treatment includes rest, physical therapy, and drug therapy. However, existing drug treatment plans often have limitations such as insignificant effects, large side effects, and inability to fundamentally solve the problem.

[0004] Many patients suffer from symptoms such as pain, numbness, and limited mobility for a long time, which seriously affects their quality of life. Therefore, there is an urgent need for a safe and effective oral agent to relieve the symptoms of patients with lumbar disc herniation, improve their condition, and improve their quality of life, so as to provide a more ideal treatment option for the majority of patients with lumbar disc herniation.

[0005] Pills are one of the traditional oral medicines of Chinese medicine. They are usually made into round solid dosage forms and are taken orally by patients to exert their efficacy. Pills are easy to take and have a long-lasting effect. They are a common form of oral medicine.

[0006] How to ensure that oral pills are effective is the current challenge, which also highlights the urgency of developing new oral medicines for lumbar disc herniation and their scientific production methods. Summary of the invention

[0007] To achieve the above objectives, the present invention is implemented through the following technical scheme: an oral medicament for lumbar disc herniation, composed of the following materials: 4-8 parts by mass of Heishun tablets, 10-20 parts by mass of Poria cocos, 5-15 parts by mass of Atractylodes macrocephala, 10-14 parts by mass of White Peony Root, 4-8 parts by mass of ginger, 10-20 parts by mass of Eucommia ulmoides, 10-14 parts by mass of Dipsacus asper, 10-20 parts by mass of Viscum album, 10-14 parts by mass of Cibotium barometz, 4-8 parts by mass of Sophora flavescens, 1-5 parts by mass of Panax notoginseng and 30-55 parts by mass of honey.

[0008] Preferably, it is composed of the following materials: 6 parts by weight of Heishun Pian, 15 parts by weight of Poria, 10 parts by weight of Atractylodes macrocephala, 12 parts by weight of White Peony Root, 6 parts by weight of Ginger, 15 parts by weight of Eucommia ulmoides, 12 parts by weight of Dipsacus asper, 15 parts by weight of Viscum album, 12 parts by weight of Cibotium barometz, 6 parts by weight of Sophora flavescens, 3 parts by weight of Panax notoginseng and 40 parts by weight of honey. Heishun Pian mainly contains alkaloids such as aconitine, which has anti-inflammatory, analgesic and cardiotonic effects, and can be used to warm the kidney and assist yang, dispel cold and relieve pain, and is used for kidney yang deficiency;

[0009] The Chinese earthworm contains a variety of active ingredients, which can play the role of breaking blood and removing blood stasis. It can break blood and remove blood stasis, fix tendons and bones, and is used for injuries caused by falls, etc.

[0010] A method for preparing an oral medicament for lumbar disc herniation, comprising the following steps:

[0011] Step 1: Put the black Shun slices into a cooking pot, soak them with water to make them fully moist, then pour out the soaking water; then add water to boil. After boiling, take them out, and crush the processed black Shun slices with a grinder to make medicinal powder A; boiling the black Shun slices with water can effectively remove the toxicity of the black Shun slices, improve the medicinal effect, and minimize the adverse effects on the body.

[0012] Step 2: After the earthworm is cleaned, it is crushed by a grinder, and the crushed powder is sieved three times to obtain a medicinal material powder B, and the medicinal material powder B is placed in a dustproof can for storage; placing the dustproof can can well improve the cleanliness and dryness of the earthworm after standing still;

[0013] Step 3. Use a grinder to grind Atractylodes macrocephala, white peony root and ginger, mix the grinded Atractylodes macrocephala, white peony root and ginger and stir-fry them in a wok, take them out and sieve them to obtain medicinal powder C; stir-frying Atractylodes macrocephala, white peony root and ginger can enhance the warming effect, help to enhance their warmth, and play an auxiliary role in regulating spleen and stomach deficiency and coldness.

[0014] Step 4: grind Poria cocos, Eucommia ulmoides, Dipsacus asper, Morus alba, Cibotium barometz and Panax notoginseng using a grinder, and then take out and sieve the ground material powder D;

[0015] Step 5. Put the honey in a boiling pot, add water and heat it, remove the foam on the surface, heat and concentrate it to make it sticky and wire-drawing. The water content of the honey is 18-20%, and the excipient is ready for use. Boiling the honey can kill bacteria, yeast and other microorganisms that may exist in it, thereby ensuring the hygiene and safety of the excipient. At the same time, the cooked honey has the effect of tonifying the middle and replenishing qi, moistening the lungs and relieving cough.

[0016] Step six, add pure water to the medicine pounder, then put the above-obtained medicinal powder A, medicinal powder B, medicinal powder C and medicinal powder D into the medicine pounder for mixing, and then during the mixing process, put the excipient into the medicine pounder in a small amount and multiple times to obtain a muddy mixture, and put the muddy mixture into a pill-making mechanism to make a preliminary pellet; putting the excipient into the medicine pounder in a small amount and multiple times can make the excipient and other medicinal materials more evenly mixed, avoiding the situation where too much is added at one time and the mixing is insufficient and uneven. Secondly, adding a small amount and multiple times facilitates better control of the amount of excipient, and can be accurately adjusted according to actual needs to achieve the best preparation effect. At the same time, it also helps to avoid waste caused by adding too much excipient at one time or affecting the quality of the final product. This method can make the entire preparation process more refined and controllable.

[0017] Step 7: Place the pellets in a suitable environment and dry them with a hot air blower to remove moisture from the pellets. Place the pellets in a spheronizer to spheronize them to make them round, thereby obtaining primary pellets.

[0018] Step eight, the primary pills are put into the hot air machine for drying again, and the drying temperature of the hot air machine is 80-100 degrees Celsius. The pills are taken out every 20 minutes and the internal moisture content is measured until the internal moisture content of the pills is less than or equal to 15.0%. The dried pills are then observed and tested, and defective pills are removed to obtain finished products.

[0019] Lower water content helps maintain the stability and shelf life of the pills. Limiting the water content within a certain range can ensure the quality of the pills, allowing them to remain in good condition for a longer period of time, making them easier to use and store.

[0020] Preferably, in the step 1, the soaking temperature of the Heishun slices is 15-25 degrees Celsius, and the soaking time is 5-10 hours; the boiling time of the Heishun slices is 1-2 hours, and the boiling temperature is 90-95 degrees Celsius.

[0021] Preferably, the mesh sizes of the three sieves in step 2 are 80 mesh for the first sieve, 100 mesh for the second sieve, and 120 mesh for the third sieve;

[0022] The described soil worm cleaning operation steps are:

[0023] S1. Select high-quality ground beetles and remove obviously deteriorated and damaged ground beetles as well as impurities between them;

[0024] S2, drying the ground beetle by a hot air blower;

[0025] S3. Use a small fan to place the pre-treated ground beetles on the air selection platform, place a 5-mesh screen on the platform, turn on the small fan, and use the wind to separate the impurities from the ground beetles and sieve them, thereby completing the ground beetle cleaning operation.

[0026] Wind selection can remove dust, debris and light impurities mixed in the earthworm, thereby improving the purity and quality of the earthworm medicinal material, making the earthworm more in line with medicinal requirements. At the same time, wind selection is also conducive to the subsequent further processing of the earthworm.

[0027] Preferably, the stir-frying temperature in step three is 200-300 degrees Celsius, and the stir-frying time is 30-60 minutes.

[0028] Preferably, in the step 4, the pulverizing time of the pulverizer is 1-2 hours, and the mesh size of the sieve is 100 meshes.

[0029] Preferably, when the cooking pot is heated in step 5, a stirring stick is used to continuously stir the mixture of honey and water therein. The continuous stirring of the stirring stick can prevent the honey in the cooking pot from becoming sticky, thereby improving the quality of the honey.

[0030] Preferably, in step 6, the pounding time of the pounder is 2-3 hours, and the excipient is put into the pounder in ten equal amounts, with an interval of 10 minutes between each addition.

[0031] Preferably, in step seven, the initial drying time of the hot air blower is 20-30 minutes, and the temperature of the hot air blower is 70-100 degrees Celsius.

[0032] The pills produced can effectively relieve the discomfort symptoms such as low back pain, radiating pain in the lower limbs, numbness, etc. in patients with lumbar disc herniation, and improve the quality of life of patients.

[0033] The present invention provides an oral medicament for lumbar disc herniation and a preparation method thereof. It has the following beneficial effects:

[0034] 1. The oral medicine for lumbar disc herniation and its preparation method, wherein the Heishun tablets mainly contain alkaloids such as aconitine, which have anti-inflammatory, analgesic, and cardiotonic effects, and can be used to warm the kidney and assist yang, dispel cold and relieve pain, and are used for kidney yang deficiency; the earthworm contains a variety of active ingredients, which can play the role of breaking blood and removing blood stasis. Breaking blood and removing blood stasis, repairing tendons and setting bones, and is used for injuries from falls.

[0035] 2. The oral medicine for lumbar disc herniation and its preparation method, wherein the toxicity of Heishun tablets can be effectively removed by decocting Heishun tablets with water and the medicinal effect can be improved; and the cleanliness and dryness of the earthworms after being placed in a dustproof jar can be greatly improved.

[0036] 3. This oral medicine for lumbar disc herniation and its preparation method. Atractylodes macrocephala, white peony root and ginger can enhance the warming effect after stir-frying, which helps to enhance their warmth and play an auxiliary role in regulating spleen and stomach deficiency and coldness.

[0037] 4. The oral medicine for lumbar disc herniation and its preparation method: boiling honey can kill bacteria, yeast and other microorganisms that may exist therein, thereby ensuring the hygiene and safety of the excipient; at the same time, the cooked honey has the effects of nourishing the middle and replenishing qi, moistening the lungs and relieving cough.

[0038] 5. The oral medicament for lumbar disc herniation and its preparation method, by adding excipients into the medicine pounder in small amounts and multiple times, the excipients can be mixed more evenly with other medicinal materials, avoiding the situation where too much is added at one time, resulting in insufficient and uneven mixing. Secondly, adding small amounts and multiple times facilitates better control of the amount of excipients, and can be accurately adjusted according to actual needs to achieve the best preparation effect. At the same time, it also helps to avoid waste caused by adding too much excipient at one time or affecting the quality of the final product. This method can make the entire preparation process more refined and controllable.

[0039] 6. The oral medicine for lumbar disc herniation and its preparation method, the lower water content of the pills helps to maintain the stability and shelf life of the pills. Limiting the water content within a certain range can ensure the quality of the pills, so that they can maintain a good state for a long time, and are easy to use and store.

[0040] 7. The oral medicine for lumbar disc herniation and its preparation method, the wind selection of earthworms can remove dust, debris and light impurities mixed in the earthworms, thereby improving the purity and quality of the earthworms, making the earthworms more in line with the medicinal requirements. At the same time, the wind selection is also conducive to the subsequent further processing of the earthworms.

[0041] 8. The oral medicine for lumbar disc herniation and its preparation method, wherein the pills can effectively relieve the discomfort symptoms such as waist pain, radiating pain in lower limbs, numbness, etc. of patients with lumbar disc herniation, and improve the quality of life of patients. DETAILED DESCRIPTION

[0042] The present invention will be further described in detail below in conjunction with specific embodiments. The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.

[0043] In the first embodiment, the present invention provides a technical solution: an oral medicament for lumbar disc herniation, composed of the following materials: 6 parts by mass of Heishun tablets, 15 parts by mass of Poria cocos, 10 parts by mass of Atractylodes macrocephala, 12 parts by mass of White Peony Root, 6 parts by mass of ginger, 15 parts by mass of Eucommia ulmoides, 12 parts by mass of Dipsacus asper, 15 parts by mass of Viscum album, 12 parts by mass of Cibotium barometz, 6 parts by mass of Sophora flavescens, 3 parts by mass of Panax notoginseng and 40 parts by mass of honey.

[0044] Heishun tablets mainly contain alkaloids such as aconitine, which have anti-inflammatory, analgesic, and cardiotonic effects. They can be used to warm the kidney and boost yang, dispel cold and relieve pain, and are used for kidney yang deficiency;

[0045] The Chinese earthworm contains a variety of active ingredients, which can play the role of breaking blood and removing blood stasis. It can break blood and remove blood stasis, fix tendons and bones, and is used for injuries caused by falls, etc.

[0046] A method for preparing an oral medicament for lumbar disc herniation, comprising the following steps:

[0047] Step 1: put the black Shun slices into a cooking pot, soak the black Shun slices with water at a temperature of 25 degrees Celsius for 10 hours to make them fully moist, and then pour out the soaking water; then add water for decoction, the decoction time of the black Shun slices is 2 hours, and the decoction temperature is 95 degrees Celsius. After decoction, take out the black Shun slices, and crush the processed black Shun slices with a grinder to prepare medicinal material powder A; decoction of the black Shun slices with water can well remove the toxicity of the black Shun slices and improve the medicinal effect.

[0048] Step 2: Clean the soil beetles. The steps for cleaning the soil beetles are as follows:

[0049] S1. Select high-quality ground beetles and remove obviously deteriorated and damaged ground beetles as well as impurities between them;

[0050] S2, drying the ground beetle by a hot air blower;

[0051] S3. Use a small fan to place the pre-treated ground beetles on the air selection platform, place a 5-mesh screen on the platform, turn on the small fan, and use the wind to separate the impurities from the ground beetles and sieve them, thereby completing the ground beetle cleaning operation.

[0052] Air separation can remove dust, debris and light impurities mixed in the earthworm, thereby improving the purity and quality of the earthworm medicinal material, making the earthworm more in line with medicinal requirements. At the same time, air separation is also conducive to the subsequent further processing of the earthworm. After the earthworm is cleaned, it is crushed with a grinder, and the crushed powder is sieved three times. The mesh numbers of the three sieves are 80 mesh for the first sieve, 100 mesh for the second sieve, and 120 mesh for the third sieve to obtain medicinal material powder B. The medicinal material powder B is placed in a dustproof jar for storage; placing it in a dustproof jar can greatly improve the cleanliness and dryness of the earthworm after it is left to stand;

[0053] Step 3. Crush the Atractylodes macrocephala, white peony root and ginger using a grinder, mix the crushed Atractylodes macrocephala, white peony root and ginger and stir-fry in a wok at a temperature of 300 degrees Celsius for 60 minutes, take out and sieve to obtain medicinal powder C; stir-frying Atractylodes macrocephala, white peony root and ginger can enhance the warming effect, help to enhance their warmth, and play an auxiliary role in regulating spleen and stomach deficiency and coldness.

[0054] Step 4: Grind Poria cocos, Eucommia ulmoides, Dipsacus asper, Morus alba, Cibotium barometz and Panax notoginseng using a grinder for 2 hours, and sieve the powder after pulverization with a sieve mesh of 100 meshes to obtain medicinal material powder D;

[0055] Step 5: Put honey in a pot, add water and heat it. When the pot is heated, use a stirring stick to continuously stir the mixture of honey and water. The continuous stirring of the stirring stick can prevent the honey in the pot from sticking to the pot and improve the quality of the honey. Remove the foam on the surface, heat and concentrate it to make it sticky and wire-drawing. The water content of the honey is 18%, and the excipient is ready for use. Boiling the honey can kill bacteria, yeast and other microorganisms that may exist in it, thereby ensuring the hygiene and safety of the excipient. At the same time, the cooked honey has the effect of replenishing the middle qi, moistening the lungs and relieving cough.

[0056] Step six, add pure water to the medicine pounder, then put the above-obtained medicinal powder A, medicinal powder B, medicinal powder C and medicinal powder D into the medicine pounder for mixing, the medicine pounder vibrates for 3 hours, and then during the mixing process, put the excipient into the medicine pounder in a small amount and multiple times, the excipient is put into the medicine pounder in ten equal amounts, and the interval time of each putting is 10 minutes to obtain a muddy mixture, and the muddy mixture is put into a pill making mechanism to make a preliminary product of pills; putting the excipient into the medicine pounder in a small amount and multiple times can make the excipient more evenly mixed with other medicinal materials, avoiding the situation where too much is added at one time and the mixing is insufficient and uneven. Secondly, adding a small amount and multiple times is convenient for better controlling the amount of the excipient, and can be accurately adjusted according to actual needs to achieve the best preparation effect. At the same time, it also helps to avoid waste caused by adding too much excipient at one time or affecting the quality of the final product. This method can make the entire preparation process more refined and controllable.

[0057] Step 7: Place the pellets in a suitable environment and preliminarily dry them with a hot air blower. The preliminarily drying time is 30 minutes and the temperature of the hot air blower is 90 degrees Celsius. The moisture of the pellets is removed and the treated pellets are placed in a spheronization machine for spheronization to make them round in appearance, thereby obtaining the primary pellets.

[0058] Step 8: Put the primary pills into the hot air machine again for drying. The drying temperature of the hot air machine is 100 degrees Celsius. The pills are taken out every 20 minutes and the internal moisture content is measured until the internal moisture content of the pills is less than 15.0%. The dried pills are then observed and tested, and defective pills are removed to obtain finished products.

[0059] Lower water content helps maintain the stability and shelf life of the pills. Limiting the water content within a certain range can ensure the quality of the pills, allowing them to remain in good condition for a longer period of time, making them easier to use and store.

[0060] The second embodiment, based on the first embodiment, the present invention provides a technical solution: an oral medicine for lumbar disc herniation, composed of the following materials: 4 parts by mass of Heishun tablets, 10 parts by mass of Poria cocos, 5 parts by mass of Atractylodes macrocephala, 10 parts by mass of White Peony Root, 4 parts by mass of ginger, 10 parts by mass of Eucommia ulmoides, 10 parts by mass of Dipsacus asper, 10 parts by mass of Viscum album, 10 parts by mass of Cibotium barometz, 4 parts by mass of Sophora flavescens, 1 part by mass of Panax notoginseng and 30 parts by mass of honey.

[0061] Heishun tablets mainly contain alkaloids such as aconitine, which have anti-inflammatory, analgesic, and cardiotonic effects. They can be used to warm the kidney and boost yang, dispel cold and relieve pain, and are used for kidney yang deficiency;

[0062] The Chinese earthworm contains a variety of active ingredients, which can play the role of breaking blood and removing blood stasis. Breaking blood and removing blood stasis, repairing tendons and setting bones, and is used for injuries caused by falls, etc.

[0063] A method for preparing an oral medicament for lumbar disc herniation, comprising the following steps:

[0064] Step 1: put the black Shun slices into a cooking pot, soak the black Shun slices with water at a temperature of 15 degrees Celsius for 5 hours to make them fully moist, and then pour out the soaking water; then add water for decoction, the decoction time of the black Shun slices is 1 hour, and the decoction temperature is 90 degrees Celsius. After decoction, take out the black Shun slices, and crush the processed black Shun slices with a grinder to prepare medicinal material powder A; decoction of the black Shun slices with water can well remove the toxicity of the black Shun slices and improve the medicinal effect.

[0065] Step 2: Clean the soil beetles. The steps for cleaning the soil beetles are as follows:

[0066] S1. Select high-quality ground beetles and remove obviously deteriorated and damaged ground beetles as well as impurities between them;

[0067] S2, drying the ground beetle by a hot air blower;

[0068] S3. Use a small fan to place the pre-treated ground beetles on the air selection platform, place a 5-mesh screen on the platform, turn on the small fan, and use the wind to separate the impurities from the ground beetles and sieve them, thereby completing the ground beetle cleaning operation.

[0069] Air separation can remove dust, debris and light impurities mixed in the earthworm, thereby improving the purity and quality of the earthworm medicinal material, making the earthworm more in line with medicinal requirements. At the same time, air separation is also conducive to the subsequent further processing of the earthworm. After the earthworm is cleaned, it is crushed with a grinder, and the crushed powder is sieved three times. The mesh numbers of the three sieves are 80 mesh for the first sieve, 100 mesh for the second sieve, and 120 mesh for the third sieve to obtain medicinal material powder B. The medicinal material powder B is placed in a dustproof jar for storage; placing it in a dustproof jar can greatly improve the cleanliness and dryness of the earthworm after it is left to stand;

[0070] Step 3. Crush the Atractylodes macrocephala, white peony root and ginger using a grinder, mix the crushed Atractylodes macrocephala, white peony root and ginger and stir-fry in a wok at a temperature of 200 degrees Celsius for 30 minutes, take out and sieve to obtain medicinal powder C; stir-frying Atractylodes macrocephala, white peony root and ginger can enhance the warming effect, help to enhance their warmth, and play an auxiliary role in regulating spleen and stomach deficiency and coldness.

[0071] Step 4: grind Poria, Eucommia, Dipsacus asper, Morus alba, Cibotium barometz and Panax notoginseng using a grinder for 1 hour, and sieve the powder after grinding with a sieve mesh of 100 meshes to obtain medicinal material powder D;

[0072] Step 5: Put honey in a pot, add water and heat it. When the pot is heated, use a stirring stick to continuously stir the mixture of honey and water. The continuous stirring of the stirring stick can prevent the honey in the pot from sticking to the pot and improve the quality of the honey. Remove the foam on the surface, heat and concentrate it to make it sticky and wire-drawing. The water content of the honey is 18%, and the excipient is ready for use. Boiling the honey can kill bacteria, yeast and other microorganisms that may exist in it, thereby ensuring the hygiene and safety of the excipient. At the same time, the cooked honey has the effect of replenishing the middle qi, moistening the lungs and relieving cough.

[0073] Step six, add pure water to the medicine pounder, then put the above-obtained medicinal powder A, medicinal powder B, medicinal powder C and medicinal powder D into the medicine pounder for mixing, the medicine pounder vibrates for 2 hours, and then during the mixing process, put the excipient into the medicine pounder in a small amount and multiple times, the excipient is put into the medicine pounder in ten equal amounts, and the interval time of each putting is 10 minutes to obtain a muddy mixture, and the muddy mixture is put into a pill making mechanism to make a preliminary product of pills; putting the excipient into the medicine pounder in a small amount and multiple times can make the excipient more evenly mixed with other medicinal materials, avoiding the situation where too much is added at one time and the mixing is insufficient and uneven. Secondly, adding a small amount and multiple times is convenient for better controlling the amount of the excipient, and can be accurately adjusted according to actual needs to achieve the best preparation effect. At the same time, it also helps to avoid waste caused by adding too much excipient at one time or affecting the quality of the final product. This method can make the entire preparation process more refined and controllable.

[0074] Step 7: Place the pellets in a suitable environment and preliminarily dry them with a hot air blower. The preliminarily drying time is 20 minutes and the temperature of the hot air blower is 70 degrees Celsius. The moisture of the pellets is removed and the treated pellets are placed in a spheronization machine for spheronization to make them round in appearance, thereby obtaining the primary pellets.

[0075] Step 8: Put the primary pills into the hot air machine again for drying. The drying temperature of the hot air machine is 80 degrees Celsius. The pills are taken out every 20 minutes and the internal moisture content is measured until the internal moisture content of the pills is less than 15.0%. The dried pills are then observed and tested, and defective pills are removed to obtain finished products.

[0076] Lower water content helps maintain the stability and shelf life of the pills. Limiting the water content within a certain range can ensure the quality of the pills, allowing them to remain in good condition for a longer period of time, making them easier to use and store.

[0077] The third embodiment, based on the first and second embodiments, the present invention provides a technical solution: an oral medicine for lumbar disc herniation, composed of the following materials: 8 parts by mass of Heishun tablets, 20 parts by mass of Poria cocos, 15 parts by mass of Atractylodes macrocephala, 14 parts by mass of White Peony Root, 8 parts by mass of ginger, 20 parts by mass of Eucommia ulmoides, 14 parts by mass of Dipsacus asper, 20 parts by mass of Viscum album, 14 parts by mass of Cibotium barometz, 8 parts by mass of Sophora flavescens, 5 parts by mass of Panax notoginseng and 55 parts by mass of honey.

[0078] Heishun tablets mainly contain alkaloids such as aconitine, which have anti-inflammatory, analgesic, and cardiotonic effects. They can be used to warm the kidney and boost yang, dispel cold and relieve pain, and are used for kidney yang deficiency;

[0079] The Chinese earthworm contains a variety of active ingredients, which can play the role of breaking blood and removing blood stasis. Breaking blood and removing blood stasis, repairing tendons and setting bones, and is used for injuries caused by falls, etc.

[0080] A method for preparing an oral medicament for lumbar disc herniation, comprising the following steps:

[0081] Step 1: put the black Shun slices into a cooking pot, soak the black Shun slices with water at a temperature of 25 degrees Celsius for 10 hours to make them fully moist, and then pour out the soaking water; then add water for decoction, the decoction time of the black Shun slices is 2 hours, and the decoction temperature is 95 degrees Celsius. After decoction, take out the black Shun slices, and crush the processed black Shun slices with a grinder to prepare medicinal material powder A; decoction of the black Shun slices with water can well remove the toxicity of the black Shun slices and improve the medicinal effect.

[0082] Step 2: Clean the soil beetles. The steps for cleaning the soil beetles are as follows:

[0083] S1. Select high-quality ground beetles and remove obviously deteriorated and damaged ground beetles as well as impurities between them;

[0084] S2, drying the ground beetle by a hot air blower;

[0085] S3. Use a small fan to place the pre-treated ground beetles on the air selection platform, place a 5-mesh screen on the platform, turn on the small fan, and use the wind to separate the impurities from the ground beetles and sieve them, thereby completing the ground beetle cleaning operation.

[0086] Air separation can remove dust, debris and light impurities mixed in the earthworm, thereby improving the purity and quality of the earthworm medicinal material, making the earthworm more in line with medicinal requirements. At the same time, air separation is also conducive to the subsequent further processing of the earthworm. After the earthworm is cleaned, it is crushed with a grinder, and the crushed powder is sieved three times. The mesh numbers of the three sieves are 80 mesh for the first sieve, 100 mesh for the second sieve, and 120 mesh for the third sieve to obtain medicinal material powder B. The medicinal material powder B is placed in a dustproof jar for storage; placing it in a dustproof jar can greatly improve the cleanliness and dryness of the earthworm after it is left to stand;

[0087] Step 3. Crush the Atractylodes macrocephala, white peony root and ginger using a grinder, mix the crushed Atractylodes macrocephala, white peony root and ginger and stir-fry in a wok at a temperature of 300 degrees Celsius for 60 minutes, take out and sieve to obtain medicinal powder C; stir-frying Atractylodes macrocephala, white peony root and ginger can enhance the warming effect, help to enhance their warmth, and play an auxiliary role in regulating spleen and stomach deficiency and coldness.

[0088] Step 4: Grind Poria cocos, Eucommia ulmoides, Dipsacus asper, Morus alba, Cibotium barometz and Panax notoginseng using a grinder for 2 hours, and sieve the powder after pulverization with a sieve mesh of 100 meshes to obtain medicinal material powder D;

[0089] Step 5: Put honey in a pot, add water and heat it. When the pot is heated, use a stirring stick to continuously stir the mixture of honey and water. The continuous stirring of the stirring stick can prevent the honey in the pot from sticking to the pot and improve the quality of the honey. Remove the foam on the surface, heat and concentrate it to make it sticky and wire-drawing. The water content of the honey is 20%, and the excipient is ready for use. Boiling the honey can kill bacteria, yeast and other microorganisms that may exist in it, thereby ensuring the hygiene and safety of the excipient. At the same time, the cooked honey has the effect of replenishing the middle qi, moistening the lungs and relieving cough.

[0090] Step six, add pure water to the medicine pounder, then put the above-obtained medicinal powder A, medicinal powder B, medicinal powder C and medicinal powder D into the medicine pounder for mixing, the medicine pounder vibrates for 3 hours, and then during the mixing process, put the excipient into the medicine pounder in a small amount and multiple times, the excipient is put into the medicine pounder in ten equal amounts, and the interval time of each putting is 10 minutes to obtain a muddy mixture, and the muddy mixture is put into a pill making mechanism to make a preliminary product of pills; putting the excipient into the medicine pounder in a small amount and multiple times can make the excipient more evenly mixed with other medicinal materials, avoiding the situation where too much is added at one time and the mixing is insufficient and uneven. Secondly, adding a small amount and multiple times is convenient for better controlling the amount of the excipient, and can be accurately adjusted according to actual needs to achieve the best preparation effect. At the same time, it also helps to avoid waste caused by adding too much excipient at one time or affecting the quality of the final product. This method can make the entire preparation process more refined and controllable.

[0091] Step 7: Place the pellets in a suitable environment and preliminarily dry them with a hot air blower. The preliminarily drying time is 30 minutes and the temperature of the hot air blower is 100 degrees Celsius. The moisture of the pellets is removed and the treated pellets are placed in a spheronization machine for spheronization to make them round in appearance, thereby obtaining the primary pellets.

[0092] Step 8: Put the primary pills into the hot air machine again for drying. The drying temperature of the hot air machine is 100 degrees Celsius. The pills are taken out every 20 minutes and the internal moisture content is measured until the internal moisture content of the pills is less than 15.0%. The dried pills are then observed and tested, and defective pills are removed to obtain finished products.

[0093] Lower water content helps maintain the stability and shelf life of the pills. Limiting the water content within a certain range can ensure the quality of the pills, allowing them to remain in good condition for a longer period of time, making them easier to use and store.

[0094] Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field and related fields without creative work should fall within the scope of protection of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention are implemented according to the conventional means in the field unless otherwise specified and limited.

Claims

1. An oral medicament for lumbar disc herniation, characterized in that: The composition comprises the following materials: 4-8 parts by weight of Heishunpian, 10-20 parts by weight of Poria cocos, 5-15 parts by weight of Atractylodes macrocephala, 10-14 parts by weight of White Peony Root, 4-8 parts by weight of Ginger, 10-20 parts by weight of Eucommia ulmoides, 10-14 parts by weight of Dipsacus asper, 10-20 parts by weight of Viscum album, 10-14 parts by weight of Cibotium barometz, 4-8 parts by weight of Sophora flavescens, 1-5 parts by weight of Panax notoginseng and 30-55 parts by weight of Honey.

2. The oral medicament for lumbar disc herniation according to claim 1, characterized in that: The composition comprises the following materials: 6 parts by mass of Heishunpian, 15 parts by mass of Poria, 10 parts by mass of Atractylodes macrocephala, 12 parts by mass of White Peony Root, 6 parts by mass of Ginger, 15 parts by mass of Eucommia ulmoides, 12 parts by mass of Dipsacus asper, 15 parts by mass of Viscum album, 12 parts by mass of Cibotium barometz, 6 parts by mass of Sophora flavescens, 3 parts by mass of Panax notoginseng and 40 parts by mass of honey.

3. A method for preparing an oral medicament for lumbar disc herniation, characterized in that: It consists of the following steps: Step 1, put the black Shun slices into a cooking pot, soak them in water to make them fully moist, and then pour out the soaking water; then add water to boil, fish out after boiling, and grind the processed black Shun slices with a grinder to make medicinal material powder A; Step 2: After cleaning the earthworm, crush it with a grinder, sieve the crushed powder three times to obtain the medicinal material powder B, and store the medicinal material powder B in a dustproof can; Step 3: Grind the Atractylodes macrocephala, white peony root and ginger using a grinder, mix the ground Atractylodes macrocephala, white peony root and ginger, stir-fry them in a wok, take them out and sieve them to obtain medicinal material powder C; Step 4: grind Poria cocos, Eucommia ulmoides, Dipsacus asper, Morus alba, Cibotium barometz and Panax notoginseng using a grinder, and then take out the ground and sieve to obtain medicinal material powder D; Step 5: Place honey in a cooking pot, add water and heat it, remove the foam on the surface, heat and concentrate it to make it sticky and wire-drawing. The water content of honey is 18-20%, and the excipient is ready for use; Step 6: Add purified water to the medicine pounder, then put the medicinal material powder A, medicinal material powder B, medicinal material powder C and medicinal material powder D obtained above into the medicine pounder for mixing, and then add excipients into the medicine pounder in small amounts and multiple times during the mixing process to obtain a mud-like mixture, and put the mud-like mixture into a pill-making mechanism to prepare a primary pellet; Step 7: Place the pellets in a suitable environment and dry them with a hot air blower to remove moisture from the pellets. Place the pellets in a spheronizer to spheronize them to make them round, thereby obtaining primary pellets. Step eight, the primary pills are put into the hot air machine for drying again, and the drying temperature of the hot air machine is 80-100 degrees Celsius. The pills are taken out every 20 minutes and the internal moisture content is measured until the internal moisture content of the pills is less than or equal to 15.0%. The dried pills are then observed and tested, and defective pills are removed to obtain finished products.

4. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: In the step 1, the soaking temperature of the Heishun slices is 15-25 degrees Celsius, and the soaking time is 5-10 hours; the boiling time of the Heishun slices is 1-2 hours, and the boiling temperature is 90-95 degrees Celsius.

5. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: The mesh sizes of the three sieves in step 2 are 80 mesh for the first sieve, 100 mesh for the second sieve, and 120 mesh for the third sieve; The described soil worm cleaning operation steps are: S1. Select high-quality ground beetles and remove obviously deteriorated and damaged ground beetles as well as impurities between them; S2, drying the ground beetle by a hot air blower; S3. Use a small fan to place the pre-treated ground beetles on the air selection platform, place a 5-mesh screen on the platform, turn on the small fan, and use the wind to separate the impurities from the ground beetles and sieve them, thereby completing the ground beetle cleaning operation.

6. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: The stir-frying temperature in step 3 is 200-300 degrees Celsius, and the stir-frying time is 30-60 minutes.

7. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: In the step 4, the pulverizing time of the pulverizer is 1-2 hours, and the mesh number of the sieve is 100 meshes.

8. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: When the cooking pot is heated in step 5, the mixture of honey and water inside is continuously stirred using a stirring stick.

9. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: In the step 6, the pounding time of the pounder is 2-3 hours, and the excipient is put into the pounder in equal amounts ten times, with an interval of 10 minutes between each addition.

10. The method for preparing an oral medicament for lumbar disc herniation according to claim 3, characterized in that: In step seven, the initial drying time of the hot air blower is 20-30 minutes, and the temperature of the hot air blower is 70-100 degrees Celsius.