Traditional Chinese medicine bowel relaxing suppository

Abstract

The invention discloses a traditional Chinese medicine bowel relaxing suppository, belongs to the technical field of biological pharmacy, and ensures the safety and obvious curative effect of the product through scientific preparation. The composition combines a nourishing and intestine moistening mixture and a modern preparation technology, and can quickly relieve constipation and adjust intestinal functions. Compared with oral administration and rectal administration, the suppository provided by the invention is more convenient to use, can be directly brought into the anus, and avoids complex operation and discomfort. In addition, the traditional Chinese medicine composition is helpful for preventing complications such as anal fissure and haemorrhoids possibly caused by long-term constipation, and the living quality of patients is The traditional Chinese medicine theory is inherited and developed, the modernization process of traditional Chinese medicine is promoted, and a new example is provided for internationalized development. Meanwhile, the traditional Chinese medicine composition has high market potential and social value, the cognition of the public on traditional Chinese medicine can be improved, healthy industry development is promoted, and contribution is made to reasonable allocation of social medical resources.

Description

Technical Field

[0001] The invention belongs to the technical field of biopharmaceuticals, and particularly relates to a Chinese medicine laxative suppository. Background Art

[0002] Constipation is a common digestive system disease, and its main symptoms are difficulty in defecation or reduced bowel movement. Long-term constipation not only affects the patient's quality of life, but may also lead to complications such as intestinal dysfunction, anal fissures, and hemorrhoids. At present, the methods for treating constipation mainly include oral medications, rectal administration, and traditional Chinese medicine treatment. Among them, although oral medications are easy to use, they are slow to take effect and are prone to side effects such as melanosis of the large intestine; although rectal administration such as enema and glycerin suppositories can quickly relieve constipation symptoms, long-term use can easily lead to dependence; and although traditional Chinese medicine treatment methods such as honey-fried laxatives have good therapeutic effects, problems such as the difficulty in obtaining materials and complex preparation limit their widespread clinical application.

[0003] In view of the deficiencies of the prior art, the present invention provides a Chinese medicine laxative suppository and a preparation method thereof. The Chinese medicine laxative suppository is based on the formula of Yangrong Runchang Shuji, and a large amount of honey is added after the effective ingredients are extracted to prepare a suppository. Clinically verified, the Chinese medicine laxative suppository of the present invention has the advantages of simple preparation, convenient use, obvious therapeutic effect, and no obvious toxic and side effects. In addition, the present invention also optimizes the dosage form characteristics of the suppository, so that the patient is more comfortable and convenient during use. Summary of the invention

[0004] The object of the present invention is to provide a Chinese medicine laxative suppository to solve the problems raised in the above background technology.

[0005] To achieve the above purpose, the present invention provides the following technical solution: a Chinese medicine laxative suppository, characterized in that it is composed of the following raw materials in parts by weight: 10-20 parts of polygonatum, 5-15 parts of bupleurum, 5-15 parts of trichosanthes seeds, 5-15 parts of apricot kernels, 5-15 parts of cassia seeds, 5-15 parts of cistanche, 5-15 parts of angelica, and 5-15 parts of achyranthes bidentata.

[0006] Preferably, honey is also included, wherein the weight of the honey is 3-5 times the total weight of all the raw materials.

[0007] Preferably, a method for preparing a Chinese medicine laxative suppository is characterized by:

[0008] a) Cleaning and drying: Take Chinese medicinal materials such as polygonatum, bupleurum, trichosanthes seed, apricot kernel, cassia seed, cistanche, angelica, and achyranthes bidentata, clean them separately to remove impurities on the surface of the medicinal materials, and then dry them to allow the moisture of the medicinal materials to evaporate appropriately, in preparation for the subsequent steps;

[0009] b) Proportional mixing: accurately weighing the cleaned and dried Chinese medicinal materials according to the weight portions specified in claim 1, and then mixing the Chinese medicinal materials uniformly to ensure that the proportion of the raw materials in each suppository is consistent;

[0010] c) Grinding into powder: Grind the mixed Chinese medicinal materials into fine powder using a medicinal material grinder or similar equipment to facilitate the extraction of effective ingredients;

[0011] d) Decoction extraction: Place the ground Chinese medicine powder and an appropriate amount of water in a decoction vessel for decoction, using a slow fire to fully extract the effective ingredients in the medicinal materials. The decoction time can be adjusted according to actual needs;

[0012] e) Filtration and purification: Filter the decoction of the Chinese medicine liquid, use gauze or a filter to remove impurities such as drug residues, and only retain the pure Chinese medicine extract;

[0013] f) Concentration and liquid preparation: Concentrating the purified Chinese medicine extract obtained by filtration, reducing the water content by means of reduced pressure concentration or room temperature evaporation, etc., to obtain a concentrated Chinese medicine extract;

[0014] g) adding honey and stirring: according to claim 2, adding honey 3-5 times the total weight of the raw material medicine to the concentrate, stirring evenly, so that the honey and the Chinese medicine extract are fully mixed to form a viscous honey Chinese medicine concentrate;

[0015] h) Molding and cooling: Pour the stirred honey Chinese medicine concentrate into the pre-prepared suppository mold, place it in a cool and dry place or use cooling equipment to cool and solidify it, and demould it after it is completely solidified to obtain a molded Chinese medicine laxative suppository.

[0016] Preferably, in step g), after adding a proper amount of honey, a proper amount of auxiliary ingredients such as preservatives and antioxidants may be added as required.

[0017] Preferably, in step h), the honey Chinese medicine concentrate can be poured into molds of different shapes and sizes to prepare Chinese medicine laxative suppositories of different specifications.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] High safety: The Chinese medicinal materials selected in the present invention are all medicinal materials commonly used in traditional Chinese medicine for moistening the intestines and relieving constipation, and have low toxic side effects. Through scientific extraction and preparation processes, the safety of the product is further ensured, reducing patients' concerns about drug dependence and potential risks.

[0020] Significant therapeutic effect: Combining the traditional Chinese medicine formula of Yangrong Runchang Shuhe with modern drug preparation technology, the Chinese medicine laxative suppository of the present invention can quickly relieve constipation symptoms, adjust intestinal function, and promote defecation reflex, and has a good long-term therapeutic effect for patients with long-term constipation.

[0021] Convenient to use: Compared with traditional oral medication and rectal administration, the suppository form of the present invention is more convenient for patients to use. The suppository can be directly inserted into the anus without complicated preparation process, and also avoids the discomfort that may be caused by oral medication.

[0022] Reduce complications: Long-term constipation may lead to complications such as anal fissures and hemorrhoids. The Chinese medicine laxative suppository of the present invention helps prevent the occurrence of these complications through the mechanism of moistening the intestines and adjusting the functions of the six internal organs.

[0023] Improve the quality of life: Constipation not only affects the patient's physical health, but also has a negative impact on their psychological and social activities. The Chinese medicine laxative suppository of the present invention can effectively relieve constipation symptoms and help patients restore normal bowel habits, thereby improving the patient's quality of life.

[0024] Promote the inheritance and development of traditional Chinese medicine: The successful development of this invention is not only a continuation and development of traditional Chinese medicine theory, but also a promotion of the modernization of traditional Chinese medicine. By combining traditional Chinese medicine with modern technology, it provides a new example for the internationalization and modernization of traditional Chinese medicine.

[0025] Both economic and social benefits are important: From the perspective of economic benefits, the Chinese medicine laxative suppository of the present invention has high market potential and commercial value. From the perspective of social benefits, the present invention helps to enhance the public's awareness and acceptance of traditional Chinese medicine, promote the development of the health industry, and also contribute to the rational allocation of social medical resources. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a flow chart of the steps of the present invention. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] See also Figure 1The present invention provides a Chinese medicine laxative suppository, characterized in that it is composed of the following raw materials in parts by weight: 10-20 parts of polygonatum, 5-15 parts of bupleurum, 5-15 parts of trichosanthes seeds, 5-15 parts of apricot kernels, 5-15 parts of cassia seeds, 5-15 parts of cistanche, 5-15 parts of angelica, and 5-15 parts of achyranthes bidentata.

[0029] Furthermore, through precise proportioning, the consistency of the active ingredients in each suppository can be ensured, thereby ensuring the stability and predictability of the therapeutic effect. This is especially important for the treatment of diseases such as constipation that require sustained and stable efficacy. In addition, the use of traditional Chinese medicinal materials can also reduce the side effects that may be caused by chemical drugs, making it safer and gentler.

[0030] In this embodiment, honey is also included, wherein the weight of the honey is 3-5 times the total weight of all the raw materials.

[0031] Furthermore, honey, as a natural laxative and antibacterial agent, can not only increase the lubricity of suppositories, making them more comfortable to use and reducing patient discomfort, but also improve the overall efficacy of the product. At the same time, honey itself has good preservation properties and can extend the shelf life of the product to a certain extent.

[0032] In this embodiment, a method for preparing a laxative suppository of traditional Chinese medicine is characterized by:

[0033] a) Cleaning and drying: Take Chinese medicinal materials such as polygonatum, bupleurum, trichosanthes seed, apricot kernel, cassia seed, cistanche, angelica, and achyranthes bidentata, clean them separately to remove impurities on the surface of the medicinal materials, and then dry them to allow the moisture of the medicinal materials to evaporate appropriately, in preparation for the subsequent steps;

[0034] b) Proportional mixing: accurately weighing the cleaned and dried Chinese medicinal materials according to the weight portions specified in claim 1, and then mixing the Chinese medicinal materials uniformly to ensure that the proportion of the raw materials in each suppository is consistent;

[0035] c) Grinding into powder: Grind the mixed Chinese medicinal materials into fine powder using a medicinal material grinder or similar equipment to facilitate the extraction of effective ingredients;

[0036] d) Decoction extraction: Place the ground Chinese medicine powder and an appropriate amount of water in a decoction vessel for decoction, using a slow fire to fully extract the effective ingredients in the medicinal materials. The decoction time can be adjusted according to actual needs;

[0037] e) Filtration and purification: Filter the decoction of the Chinese medicine liquid, use gauze or a filter to remove impurities such as drug residues, and only retain the pure Chinese medicine extract;

[0038] f) Concentration and liquid preparation: Concentrating the purified Chinese medicine extract obtained by filtration, reducing the water content by means of reduced pressure concentration or room temperature evaporation, etc., to obtain a concentrated Chinese medicine extract;

[0039] g) adding honey and stirring: according to claim 2, adding honey 3-5 times the total weight of the raw material medicine to the concentrate, stirring evenly, so that the honey and the Chinese medicine extract are fully mixed to form a viscous honey Chinese medicine concentrate;

[0040] h) Molding and cooling: Pour the stirred honey Chinese medicine concentrate into the pre-prepared suppository mold, place it in a cool and dry place or use cooling equipment to cool and solidify it, and demould it after it is completely solidified to obtain a molded Chinese medicine laxative suppository.

[0041] Furthermore, through this series of refined operation processes, the effective ingredients in the medicinal materials can be extracted to the greatest extent, while ensuring the purity and safety of the products. In addition, the detailed preparation process also provides a standardized operation guide for the large-scale production of the products.

[0042] In this embodiment, in step g), after adding a proper amount of honey, a proper amount of auxiliary ingredients such as preservatives and antioxidants may be added as needed.

[0043] Furthermore, the addition of these auxiliary ingredients can further enhance the stability of the product, prevent microbial contamination and oxidation of chemical components, and ensure the safety and effectiveness of the product during use.

[0044] In this embodiment, in step h), the honey Chinese medicine concentrate can be poured into molds of different shapes and sizes to prepare Chinese medicine laxative suppositories of different specifications.

[0045] Furthermore, this flexibility enables the product to better adapt to the needs of different patients. Whether adults or children, they can find product specifications that suit them, thereby improving patients' convenience of use and treatment compliance.

[0046] The working principle and use process of the present invention:

[0047] First, in the preparation stage of medicinal materials, it is necessary to take 10-20 parts of polygonatum, 5-15 parts of bupleurum, 5-15 parts of trichosanthes, 5-15 parts of apricot kernel, 5-15 parts of cassia seed, 5-15 parts of cistanche, 5-15 parts of angelica, 5-15 parts of achyranthes bidentata and other Chinese medicinal materials according to the weight parts specified in the claims. These medicinal materials all have the traditional Chinese medicine effect of moistening the intestines and relieving constipation, and they are all common Chinese medicinal materials, easy to collect and store, and then enter the cleaning and drying stage. The above medicinal materials are thoroughly cleaned to remove impurities on the surface, and then dried to evaporate the moisture in the medicinal materials appropriately. This step is very important to ensure the quality and safety of the final product. The third step is to mix the proportions. The cleaned and dried Chinese medicinal materials are weighed according to the precise weight parts and then mixed evenly. It is very important to ensure the consistency of the proportion of raw materials in each suppository to ensure the stability of the efficacy of the product. The next step is the grinding stage. The mixed Chinese medicinal materials are ground and ground into fine powder using a medicinal material grinder or similar equipment. This helps to better release the active ingredients in the medicinal materials in the subsequent extraction process. The fifth step is decoction extraction. The ground Chinese medicine powder is placed in a decoction device together with an appropriate amount of water, and the active ingredients in the medicinal materials are fully extracted by slow boiling. The decoction time is adjusted according to actual needs to ensure the maximum extraction of the efficacy. The sixth step is filtration and purification. The decoction of the Chinese medicine liquid is filtered through gauze or a filter to remove impurities such as drug residues, leaving only pure Chinese medicine extract. This step ensures the convenience and comfort of product use. The seventh step is concentrated liquid preparation. The pure Chinese medicine extract obtained by filtration is concentrated, and the water content is reduced by vacuum concentration or room temperature evaporation to obtain a concentrated Chinese medicine extract. This step further improves the concentration and efficacy of the medicinal materials. The eighth step is to add honey and stir. Add 3-5 times the total weight of the raw material honey to the concentrate, stir evenly, and fully mix the honey and the Chinese medicine extract to form a viscous honey Chinese medicine concentrate. Honey not only increases the lubricity of the suppository, but also improves the taste, making the patient more comfortable during use. The ninth step is molding and cooling. Pour the stirred honey Chinese medicine concentrate into the prepared suppository mold, place it in a cool and dry place or use cooling equipment to cool and solidify it. After it is completely solidified, demould it to obtain the formed Chinese medicine laxative suppository. The last step is packaging and storage. The prepared Chinese medicine laxative suppository is properly packaged, marked with production date, expiration date and other information, and stored in a cool and dry place to maintain the stability and effectiveness of the product.

[0048] The electronic components and modules used in the invention can be parts commonly used in the market and can realize the specific functions in this case, and the specific models and sizes can be selected and adjusted according to actual needs.

[0049] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A Chinese medicine laxative suppository, characterized in that: The invention is composed of the following raw materials in parts by weight: 10-20 parts of polygonatum, 5-15 parts of bupleurum, 5-15 parts of trichosanthes seeds, 5-15 parts of apricot kernels, 5-15 parts of cassia seeds, 5-15 parts of cistanche, 5-15 parts of angelica and 5-15 parts of achyranthes bidentata.

2. A Chinese medicine laxative suppository according to claim 1, characterized in that: It also includes honey, wherein the weight of the honey is 3-5 times the total weight of all raw materials.

3. The method for making a Chinese medicine laxative suppository according to claim 2, characterized in that: a) Cleaning and drying: Take Chinese medicinal materials such as polygonatum, bupleurum, trichosanthes seed, apricot kernel, cassia seed, cistanche, angelica, and achyranthes bidentata, clean them separately to remove impurities on the surface of the medicinal materials, and then dry them to allow the moisture of the medicinal materials to evaporate appropriately, in preparation for the subsequent steps; b) Proportional mixing: accurately weighing the cleaned and dried Chinese medicinal materials according to the weight portions specified in claim 1, and then mixing the Chinese medicinal materials uniformly to ensure that the proportion of the raw materials in each suppository is consistent; c) Grinding into powder: Grind the mixed Chinese medicinal materials into fine powder using a medicinal material grinder or similar equipment to facilitate the extraction of effective ingredients; d) Decoction extraction: Place the ground Chinese medicine powder and an appropriate amount of water in a decoction vessel for decoction, using a slow fire to fully extract the effective ingredients in the medicinal materials. The decoction time can be adjusted according to actual needs; e) Filtration and purification: Filter the decoction of the Chinese medicine liquid, use gauze or a filter to remove impurities such as drug residues, and only retain the pure Chinese medicine extract; f) Concentration and liquid preparation: Concentrating the purified Chinese medicine extract obtained by filtration, reducing the water content by means of reduced pressure concentration or room temperature evaporation, etc., to obtain a concentrated Chinese medicine extract; g) adding honey and stirring: according to claim 2, adding honey 3-5 times the total weight of the raw material medicine to the concentrate, stirring evenly, so that the honey and the Chinese medicine extract are fully mixed to form a viscous honey Chinese medicine concentrate; h) Molding and cooling: Pour the stirred honey Chinese medicine concentrate into the pre-prepared suppository mold, place it in a cool and dry place or use cooling equipment to cool and solidify it, and demould it after it is completely solidified to obtain a molded Chinese medicine laxative suppository.

4. A Chinese medicine laxative suppository according to claim 3, characterized in that: In step g), after adding a proper amount of honey, appropriate amounts of auxiliary ingredients such as preservatives, antioxidants, etc. may be added as needed.

5. A Chinese medicine laxative suppository according to claim 4, characterized in that: In step h), the honey Chinese medicine concentrate can be poured into molds of different shapes and sizes to prepare Chinese medicine laxative suppositories of different specifications.

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