A sample detection device

Abstract

This application relates to the technical field of medical devices and provides a sample detection device, which includes a swab and a detection cartridge. The swab includes a sampling part; the detection cartridge is provided with a reaction chamber, a liquid flow channel, and a test strip embedding groove; a liquid storage sac is arranged in the reaction chamber, the swab can be inserted into the reaction chamber, and the sampling part can pierce the liquid storage sac; one end of the liquid flow channel is communicated with the reaction chamber, the test strip embedding groove is communicated with the liquid flow channel, and the other end of the liquid flow channel is communicated with the outside. In the solution of this application, when a user conducts a detection, usually only a swab is needed to obtain the detection sample, and then the action of piercing the liquid storage sac can be carried out. The use is simpler and more convenient, which can facilitate improving the accuracy and reliability of the detection result.

Description

Technical Field

[0001] This application relates to the technical field of medical devices, and more particularly, to a sample detection device. Background Art

[0002] In the current self-test methods on the market, colloidal gold test strips are usually used for detection. When in use, the user prepares the sample by themselves, and then touches one end of the colloidal gold test strip with the sample. After a certain reaction time, the detection result is confirmed by observing the color development band on the colloidal gold test strip.

[0003] In most sample detections, such as blood, urine, saliva, etc., due to different detection requirements, the sample usually needs to be diluted with a diluent before detection. At this time, tools such as swabs, diluents, and test strips are required. The combined use of multiple tools will lead to cumbersome operations and inconvenient use; especially for non-professional testers, manual operations are likely to cause large detection errors, thereby reducing the accuracy and reliability of the detection results. Summary of the Invention

[0004] In order to overcome at least one of the above-mentioned disadvantages in the prior art, the purpose of this application is to provide a sample detection device.

[0005] The technical means adopted by this application to solve the above technical problems is:

[0006] This application provides a sample detection device, including:

[0007] A swab, the swab includes a sampling part;

[0008] A detection box, the detection box is provided with a reaction cavity, a liquid flow channel, and a test strip embedding groove;

[0009] A liquid storage sac is arranged in the reaction cavity, the swab can be inserted into the reaction cavity, and the sampling part pierces the liquid storage sac;

[0010] One end of the liquid flow channel is communicated with the reaction cavity, the test strip embedding groove is communicated with the liquid flow channel, and the other end of the liquid flow channel is communicated with the outside.

[0011] In the solution of the present application, through the provided reaction chamber, it is convenient for the sampling part to provide a space for the reaction between the sampling part and the liquid in the liquid storage sac after piercing the liquid storage sac; through the provided test strip embedding groove, it is convenient for placing detection tools such as test strips. The liquid after the reaction flows out through the liquid flow channel and is sucked by the detection tool to obtain the detection result. In the whole process, the user only needs to use a swab to obtain the detection sample and then perform the action of piercing the liquid storage sac, which is simpler and more convenient to use and can improve the accuracy and reliability of the detection result.

[0012] In some embodiments, there is one test strip embedding groove provided.

[0013] Or, there are multiple test strip embedding grooves provided, and the multiple test strip embedding grooves are arranged side by side, and the liquid flow channel is located at the same end of the multiple test strip embedding grooves.

[0014] In the solution of the present application, by setting the test strip embedding grooves in a multiple form, it is convenient for placing multiple detection tools such as test strips, so as to facilitate multiplex detection and is more convenient to use.

[0015] In some embodiments, a test strip is arranged in the test strip embedding groove.

[0016] In the solution of the present application, through the provided test strip, it can be used to detect the mixed liquid in the reaction chamber to obtain the corresponding detection result.

[0017] In some embodiments, a result observation area is provided on the detection box, and at least part of the test strip embedding groove overlaps with the result observation area.

[0018] In the solution of the present application, through the provided result observation area, it is convenient for the user to directly observe the detection result.

[0019] In some embodiments, the end of the liquid flow channel is communicated with the outside. When the test strip embedding groove is placed vertically, the position height of the end of the liquid flow channel is higher than the position height of the connection between the test strip embedding groove and the liquid flow channel.

[0020] In the solution of the present application, by designing the position height of the end of the liquid flow channel, it is convenient to control the suction amount of the detection tool for the mixed liquid in the reaction chamber, thereby improving the reliability of the detection.

[0021] In some embodiments, the end of the liquid flow channel is communicated with the outside. When the test strip embedding groove is placed vertically, the position height of the end of the liquid flow channel is lower than the position height of the connection between the test strip embedding groove and the liquid flow channel;

[0022] A bending section is provided between the end of the liquid flow channel and the communication end of the test strip embedding groove and the liquid flow channel, and the position height of at least a part of the bending section is higher than the position height of the communication part of the test strip embedding groove and the liquid flow channel.

[0023] In the solution of the present application, through the provided bending section, the position height of the end of the liquid flow channel can have more setting options, and the shear force can be better formed during the flow of the mixed liquid, so that the mixed liquid and the detection tool can be quickly separated after being aspirated, which is convenient for reducing the possibility of cross-mixing between samples in the multiplex detection, thereby improving the reliability of the detection result.

[0024] In some embodiments, along the conveying direction of the liquid flow channel, the bending section includes a first diameter-width section and a second diameter-width section, and the diameter-width of the first diameter-width section is greater than that of the second diameter-width section.

[0025] In the solution of the present application, through the different diameter-width designs between the first diameter-width section and the second diameter-width section, it is convenient to control the flow rate of the mixed liquid.

[0026] In some embodiments, an air flow channel is provided on the detection box, one end of the air flow channel is communicated with the reaction chamber, and the other end of the air flow channel is communicated with the outside;

[0027] When the test strip embedding groove is placed vertically, the position height of the air flow channel is higher than the position height of the communication part of the liquid flow channel and the reaction chamber.

[0028] In the solution of the present application, through the provided air flow channel, it is convenient to balance the air pressure in the reaction chamber and the liquid flow channel, so that the transportation of the mixed liquid can be smoother.

[0029] In some embodiments, the air flow channel is bent.

[0030] In the solution of the present application, by setting the air flow channel in a bent form, it is possible to prevent the mixed liquid from accidentally leaking out of the air flow channel and improve the safety during the detection process.

[0031] In some embodiments, one end of the test strip embedding groove is communicated with the liquid flow channel, and the other end of the test strip embedding groove is communicated with the outside;

[0032] Or, a protruding part is provided in the test strip embedding groove, and an air hole communicated with the outside is provided in the protruding part.

[0033] In the solution of the present application, by setting the test strip embedding groove to be communicated with the outside, the communication between the liquid flow channel and the outside can be indirectly realized, which is convenient for the smooth progress of the detection process.

[0034] In some embodiments, a narrow - mouth structure for achieving communication is provided between the liquid flow channel and the reaction chamber.

[0035] In the solution of the present application, through the provided narrow - mouth structure, it is possible to facilitate the control of the outflow speed of the mixed liquid in the reaction chamber, so as to be more conducive to the mixed liquid entering the liquid flow channel.

[0036] In some embodiments, the insertion direction of the swab in the reaction chamber is opposite to the direction in which the liquid flows from the reaction chamber to the liquid flow channel;

[0037] or, the insertion direction of the swab in the reaction chamber is the same as the direction in which the liquid flows from the reaction chamber to the liquid flow channel.

[0038] In some embodiments, the reaction chamber has an opening communicating with the side surface of the test kit, and the swab is inserted through the opening and forms a seal with the test kit.

[0039] In the solution of the present application, through the provided opening, it is possible to facilitate the insertion of the swab in the reaction chamber and the realization of the sealing function between the swab and the test kit.

[0040] In some embodiments, the sampling part is conically arranged.

[0041] In the solution of the present application, by designing the shape and structure of the sampling part, it is possible to facilitate the smoothness of the piercing action of the sampling part on the liquid storage sac, and make the outflow of the liquid in the liquid storage sac smoother.

[0042] In some embodiments, a valve body mechanism is provided at the liquid inlet end of the liquid flow channel, and the valve body mechanism is used to control the communication between the liquid flow channel and the reaction chamber.

[0043] In the solution of the present application, through the provided valve body mechanism, the flow of the mixed liquid in the liquid flow channel can be controlled according to actual needs.

[0044] In some embodiments, a sliding rod is arranged in the swab, and the sliding rod can move to abut against the valve body mechanism.

[0045] In the solution of the present application, through the provided sliding rod, it is possible to facilitate the control of the state of the valve body mechanism.

[0046] In some embodiments, a control pump is provided at the liquid inlet end of the liquid flow channel, and the control pump is used to control the communication between the liquid flow channel and the reaction chamber.

[0047] In the solution of the present application, through the provided control pump, the flow of the mixed liquid in the liquid flow channel can be controlled according to actual requirements.

[0048] In some embodiments, a jet port is provided on the reaction chamber and / or the swab, and the setting position of the jet port is higher than the liquid level height in the reaction chamber.

[0049] In the solution of the present application, through the provided jet port, it is convenient to provide internal pressure to promote the flow of the mixed liquid in the liquid flow channel.

[0050] In some embodiments, the swab includes a handle portion, and a vibrator is provided inside the handle portion.

[0051] In the solution of the present application, through the provided vibrator, the swab can have a certain vibration effect, thereby facilitating the improvement of the mixing reaction effect of the mixed liquid.

[0052] In some embodiments, the vibrator is connected to a control switch, and the control switch is convexly provided and forms a contact fit with the inner wall surface of the detection box.

[0053] In the solution of the present application, through the provided control switch and making the control switch form a contact fit with the inner wall surface of the detection box, the swab will trigger the control switch after being inserted in place, thereby starting the vibration mode.

[0054] In some embodiments, the vibrator and the control switch are arranged on a control circuit board, and an indicator light is provided on the control circuit board.

[0055] In the solution of the present application, through the provided indicator light, the current operation state of the sample detection device can be prompted, avoiding misoperation by the user during the mixing process, thereby further improving the reliability of the device.

[0056] In some embodiments, a receiving cavity for placing the swab is provided in the detection box.

[0057] In the solution of the present application, through the provided receiving cavity, it is convenient to store and place the swab on the detection box, making the overall storage of the device more convenient.

[0058] In some embodiments, the test strip embedding groove is provided on the same side of the reaction chamber;

[0059] Or, the test strip embedding grooves are arranged on both sides of the reaction chamber.

[0060] Other features and advantages of the solution of this application will be described in the subsequent specification, or some features and advantages can be inferred from the content of the specification or determined without doubt, or can be learned by implementing the above embodiments of this application solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] To more clearly illustrate the technical solutions of the embodiments of this application, the following briefly introduces the drawings required to be used in the embodiments of this application. It should be understood that the following drawings only show some embodiments of this application, and thus should not be regarded as a limitation on the scope. For those of ordinary skill in the art, other related drawings can also be obtained based on these drawings without creative efforts.

[0062] Figure 1 It is a schematic structural diagram of a sample detection device under one example of this application.

[0063] Figure 2 It is a schematic diagram of the setting of a liquid flow channel under one example of this application.

[0064] Figure 3 It is a schematic cross-sectional structural diagram at the swab under one example of this application.

[0065] Figure 4 It is a schematic structural diagram of a swab under one example of this application.

[0066] Figure 5 It is a schematic structural diagram of a liquid storage sac under one example of this application.

[0067] Figure 6 It is a schematic structural diagram of a sample detection device under another example of this application.

[0068] Figure 7 It is a schematic diagram of the setting of a liquid flow channel under another example of this application.

[0069] Figure 8 It is a schematic cross-sectional structural diagram at the swab under another example of this application.

[0070] Figure 9 It is a schematic structural diagram of a swab under another example of this application.

[0071] Figure 10 It is a schematic structural diagram of a liquid storage sac under another example of this application.

[0072] Figure 11 It is a schematic structural diagram of a sample detection device under yet another example of this application.

[0073] Figure 12 It is a schematic structural diagram of an accommodation cavity under yet another example of this application.

[0074] Figure 13Schematic diagram of the setting of the liquid flow channel in another example of this application.

[0075] Figure 14 Schematic cross-sectional structure diagram of the sample detection device in another example of this application.

[0076] Figure 15 Schematic structure diagram of the swab in another example of this application.

[0077] Figure 16 Schematic application diagram of the sample detection device in one example of this application.

[0078] Figure 17 Schematic application diagram of the sample detection device in one example of this application.

[0079] Figure 18 Schematic application diagram of the sample detection device in one example of this application.

[0080] Figure 19 Schematic application diagram of the sample detection device in one example of this application.

[0081] Marking description:

[0082] 1 - Swab, 11 - Sampling part, 12 - Sealing ring, 13 - Sliding rod, 14 - Jet orifice, 15 - Handle part, 151 - Vibrator, 152 - Control switch, 153 - Control circuit board;

[0083] 2 - Detection box, 201 - Box body, 202 - Cover plate;

[0084] 21 - Reaction cavity, 211 - Narrow - mouth structure, 212 - Opening, 22 - Liquid flow channel, 221 - Horizontal section, 222 - Bend - around section, 2221 - First diameter - width section, 2222 - Second diameter - width section, 23 - Test strip embedding groove, 231 - Protrusion, 232 - Air hole, 24 - Result observation area, 25 - Air flow channel, 26 - Accommodation cavity;

[0085] 3 - Liquid storage sac, 31 - Mixed liquid, 32 - Film structure;

[0086] 4 - Detection test strip, 41 - Display area;

[0087] 5 - Electric control valve;

[0088] 6 - Mechanical valve;

[0089] 7 - Control pump. Detailed implementation manners

[0090] In order to more clearly understand the above-mentioned objects, features and advantages of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. It should be noted that, without conflict, the embodiments of the present application and the features in the embodiments can be combined with each other. In the following description, many specific details are set forth in order to fully understand the present invention. The described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the scope of protection of the present invention.

[0091] It should be noted that: Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present invention belongs. The terms used in the specification of the present invention herein are only for the purpose of describing specific embodiments, and are not intended to limit the present invention. Similar reference numerals and letters denote similar items in the following drawings. Therefore, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings. At the same time, in the description of the present application, the terms "first", "second", etc. are only used for distinguishing descriptions, and cannot be understood as indicating or implying relative importance.

[0092] At present, people are paying more and more attention to their own health problems. Under permitted conditions, based on factors such as personal privacy, convenience, and medical conditions, people tend to perform self-tests more. In conventional detection methods, usually detection tools such as test strips and dipsticks are used to detect samples to obtain detection results. However, in most sample detection operations, the samples often need to be pretreated, such as dilution treatment, etc., and then the samples are detected after being treated. In this way, due to their own professional level limitations, many people cannot well grasp the dosage of the treatment solution and the suction amount of the detection tools, resulting in a large deviation in the final detection results. Moreover, the detection tools, sampling swabs, and treatment solutions are separately arranged, the operation is cumbersome, and it is easy to cause pouring and overflow, which does not meet the hygiene requirements. Even the detection tools come into contact with other substances in advance, resulting in a significant reduction in the accuracy and reliability of the final detection results.

[0093] Aiming at the above technical problems, the purpose of the solution of this embodiment is to provide a sample detection device, which makes the detection operation simpler and can facilitate improving the accuracy and reliability of the detection results for the convenience of users.

[0094] As Figures 1 to 19 shown, the solution of this embodiment provides a sample detection device, including:

[0095] A swab 1, the swab 1 includes a sampling part 11;

[0096] Detection cassette 2, the detection cassette 2 is provided with a reaction chamber 21, a liquid flow channel 22 and a test strip embedding groove 23;

[0097] A liquid storage sac 3 is arranged in the reaction chamber 21, the swab 1 can be inserted and arranged in the reaction chamber 21, and the sampling part 11 pierces the liquid storage sac 3;

[0098] One end of the liquid flow channel 22 is communicated with the reaction chamber 21, the test strip embedding groove 23 is communicated with the liquid flow channel 22, and the other end of the liquid flow channel 22 is communicated with the outside.

[0099] In some embodiments, such as Figure 4 , Figure 9 , Figure 15 As shown, the sampling part 11 is arranged at the front end of the swab 1 for dipping the detection sample, such as urine, blood, saliva, etc., so as to facilitate the subsequent detection operation of the sample.

[0100] In some embodiments, such as Figure 1 , Figure 5 , Figure 11 As shown, the detection cassette 2 is arranged in a rectangular body. It should be understood that on the basis of similar or identical features, structural compositions and functions, the appearance shape of the detection cassette 2 includes but is not limited to being arranged in a rectangular body. In this embodiment, the detection cassette 2 arranged in a rectangular body is mainly used for exemplary illustration.

[0101] In some embodiments, such as Figure 2 , Figure 7 , Figure 13 As shown, for the convenience of processing, production and use, the reaction chamber 21, the liquid flow channel 22 and the test strip embedding groove 23 are opened on the side surface of the detection cassette 2. For example, the reaction chamber 21, the liquid flow channel 22 and the test strip embedding groove 23 are simultaneously arranged on one large side surface of the detection cassette 2, so that the operation can be more convenient and intuitive.

[0102] In some embodiments, in order to facilitate improving the side surface and space utilization rate of the detection cassette 2, the reaction chamber 21, the liquid flow channel 22 and the test strip embedding groove 23 can also be respectively arranged on different side surfaces of the detection cassette 2, but the liquid flow channel 22 still needs to communicate the reaction chamber 21 and the test strip embedding groove 23, and the specific setting form is not limited here.

[0103] In some embodiments, such as Figure 5 , Figure 10As shown, the liquid storage bag 3 is a prefabricated independent component, so that the liquid storage bag 3 can be detachably installed on the test box 2. Moreover, since the liquid storage bag 3 is a prefabricated part, the composition and dosage of the liquid in the liquid storage bag 3 are also prefabricated, and users do not need to perform any mixing operations during use, making the detection operation simpler and more efficient.

[0104] In some embodiments, the liquid storage bag 3 stores a diluent for diluting a sample and obtaining a mixed liquid 31 after dilution.

[0105] In some embodiments, as Figure 6 , Figure 7 , Figure 10 shown, along the insertion direction of the swab 1 in the reaction chamber 21, the liquid storage bag 3 is installed at the end of the reaction chamber 21. At this time, the wall surface of the liquid storage bag 3 facing the swab 1 is provided with a thin film structure 32, so that the swab 1 can pierce through the thin film structure 32 and then enter the liquid storage bag 3, and it is also convenient for the liquid in the liquid storage bag 3 to flow out.

[0106] In some embodiments, as Figure 2 , Figure 3 , Figure 5 , Figure 14 , Figures 16 to 19 shown, along the insertion direction of the swab 1 in the reaction chamber 21, the liquid storage bag 3 is installed at the front end or the middle of the reaction chamber 21. At this time, the wall surfaces of the liquid storage bag 3 facing and facing away from the swab 1 are provided with a thin film structure 32, so that the swab 1 can pass through the liquid storage bag 3 transversely.

[0107] By providing the reaction chamber 21, it is convenient for the sampling part 11 to provide a space for the sampling part 11 and the liquid in the liquid storage bag 3 to react after piercing the liquid storage bag 3. At this time, the sampling part 11 carrying the sample and the liquid flowing out of the liquid storage bag 3 are mixed in the reaction chamber 21. By providing the test strip embedding groove 23, it is convenient to place detection tools such as the test strip 4. The liquid after the mixing reaction flows out through the liquid flow channel 22 and is sucked by the detection tool to obtain the detection result. During the whole process, the user usually only needs to use the swab 1 to obtain the test sample and then pierce the liquid storage bag 3, which is simpler and more convenient to use and can improve the accuracy and reliability of the test result.

[0108] As an application example, there is one test strip embedding groove 23;

[0109] Alternatively, a plurality of strip embedding grooves 23 are provided, and the plurality of strip embedding grooves 23 are arranged side by side, and the liquid flow channel 22 is located at the same end of the plurality of strip embedding grooves 23.

[0110] In some embodiments, one strip embedding groove 23 is provided on the detection box 2. Since the number of strip embedding grooves 23 is small, the overall path of the liquid flow channel 22 can be set to be short at this time. Therefore, the volume of the entire sample detection device can be more inclined to a compact design.

[0111] In some embodiments, such as Figure 2 , Figure 7 , Figure 13 As shown, a plurality of strip embedding grooves 23 are provided on the detection box 2. Herein, "a plurality" refers to two; at this time, the plurality of strip embedding grooves 23 are arranged side by side, and the connection between each strip embedding groove 23 and the liquid flow channel 22 is located on the same horizontal straight line, so that the relative distances from different strip embedding grooves 23 to the liquid flow channel 22 are close or the same. The design of the plurality of strip embedding grooves 23 can facilitate the multi-link detection operation, thereby facilitating the acquisition of detection results under different detection requirements.

[0112] By setting the strip embedding grooves 23 in a plurality of forms, it is convenient to place detection tools such as a plurality of detection strips 4, so as to facilitate multi-link detection and is more convenient to use.

[0113] As an application example, referring to Figure 7 As shown, a detection strip 4 is provided in the strip embedding groove 23.

[0114] In some embodiments, a display area 41 is provided on the detection strip 4, such as a color display strip, etc., so as to facilitate the user to judge the detection result.

[0115] In some embodiments, the size of the strip embedding groove 23 is adapted to the size of the detection strip 4, so as to improve the stability of the detection strip 4 after being installed in the strip embedding groove 23.

[0116] Through the provided detection strip 4, it can be used to suck and detect the mixed liquid flowing out of the reaction chamber 21 into the liquid flow channel 22, so as to obtain corresponding detection results.

[0117] As an application example, referring to Figure 5 As shown, a result observation area 24 is provided on the detection box 2, and at least part of the strip embedding groove 23 overlaps with the result observation area 24.

[0118] In some embodiments, such asFigure 5 As shown, the test cartridge 2 includes a cartridge body 201 and a cover plate 202. The reaction chamber 21, the liquid flow channel 22, and the test strip embedding groove 23 are opened on the outer side surface of the cartridge body 201, and then the cover plate 202 is installed on the cartridge body 201 to form an enclosure and seal.

[0119] In some embodiments, as Figure 5 shown, the result observation area 24 is a plurality of transparent windows provided on the cover plate 202, and the positions of these transparent windows correspond to the positions where the display area 41 of the test strip 4 is located.

[0120] In some embodiments, the cover plate 202 is provided in a transparent manner. At this time, the entire cover plate 202 can function as the result observation area 24.

[0121] In some embodiments, the cover plate 202 is provided as a transparent film, and the transparent film is attached to the cartridge body 201 to form a seal, and the overall structure is also simpler.

[0122] By providing the result observation area 24, it is convenient for users to directly observe the detection results.

[0123] As one of the application examples, reference can be made to Figure 16 shown, the end of the liquid flow channel 22 is communicated with the outside. When the test strip embedding groove 23 is placed vertically, the position height of the end of the liquid flow channel 22 is higher than the position height of the connection between the test strip embedding groove 23 and the liquid flow channel 22.

[0124] In some embodiments, the liquid flow channel 22 includes a horizontal section 221, and the test strip embedding grooves 23 are all communicatively provided on the horizontal section 221; at this time, the height difference in the vertical direction between the end of the liquid flow channel 22 and the horizontal section 221 corresponds to the liquid level height that the suction end of the test strip 4 can directly contact.

[0125] By designing the position height of the end of the liquid flow channel 22, it is convenient to control the suction amount of the detection tool for the mixed liquid flowing from the reaction chamber 21 to the liquid flow channel 22, thereby facilitating the improvement of the detection reliability.

[0126] As one of the application examples, as Figure 2 shown, the end of the liquid flow channel 22 is communicated with the outside. When the test strip embedding groove 23 is placed vertically, the position height of the end of the liquid flow channel 22 is lower than the position height of the connection between the test strip embedding groove 23 and the liquid flow channel 22;

[0127] A bending section 222 is provided between the end of the liquid flow channel 22 and the connection between the test strip embedding groove 23 and the liquid flow channel 22, and the position height of at least a part of the bending section 222 is higher than the position height of the connection between the test strip embedding groove 23 and the liquid flow channel 22.

[0128] In some embodiments, the bending section 222 is arranged in an "m" shape.

[0129] By providing the bending section 222, the position height of the end of the liquid flow channel 22 can have more setting options, and a better shear force can be formed during the flow of the mixed liquid, so that the mixed liquid and the detection tool can be quickly separated after being aspirated, which is convenient for reducing the possibility of cross-mixing between samples in multiplex detection, thereby improving the reliability of the detection results.

[0130] As an application example, continue to refer to Figure 2 As shown, along the conveying direction of the liquid flow channel 22, the bending section 222 includes a first diameter-width section 2221 and a second diameter-width section 2222, and the diameter-width of the first diameter-width section 2221 is greater than that of the second diameter-width section 2222.

[0131] In some embodiments, a gradual transition connection is adopted between the first diameter-width section 2221 and the second diameter-width section 2222, such as setting a tapered section to connect the first diameter-width section 2221 and the second diameter-width section 2222 respectively, so that the flow of the mixed liquid can be smoother.

[0132] Through the different diameter-width designs between the first diameter-width section 2221 and the second diameter-width section 2222, it is convenient to control the flow rate of the mixed liquid, so that the flow rate of the mixed liquid in the second diameter-width section 2222 is greater than that in the first diameter-width section 2221.

[0133] As an application example, as Figure 1 、 Figure 2 、 Figure 13 As shown, an air flow channel 25 is provided on the detection box 2, one end of the air flow channel 25 is communicated with the reaction chamber 21, and the other end of the air flow channel 25 is communicated with the outside;

[0134] When the test strip embedding groove 23 is placed vertically, the position height of the air flow channel 25 is higher than the position height of the connection between the liquid flow channel 22 and the reaction chamber 21.

[0135] In some embodiments, the air flow channel 25 is opened on the side surface of the detection box 2.

[0136] In some embodiments, the connection between the air flow passage 25 and the reaction chamber 21 is provided at the middle position of the reaction chamber 21 to avoid the two end spaces of the reaction chamber 21 and prevent interference with the mixed liquid. For example, Figure 2 , Figure 13 as shown.

[0137] By providing the air flow passage 25, the air pressure balance between the reaction chamber 21 and the liquid flow passage 22 can be facilitated, making the transportation of the mixed liquid smoother.

[0138] As an application example, as Figure 2 , Figure 13 shown, the air flow passage 25 is arranged in a winding shape.

[0139] In some embodiments, the air flow passage 25 is arranged in an "S" shape.

[0140] By arranging the air flow passage 25 in a winding shape, accidental leakage of the mixed liquid from the air flow passage 25 can be avoided, improving the safety and reliability during the detection process.

[0141] As an application example, referring to Figure 7 , Figure 13 shown, one end of the test strip embedding groove 23 is communicated with the liquid flow passage 22, and the other end of the test strip embedding groove 23 is communicated with the outside;

[0142] Alternatively, a protruding portion 231 is provided in the test strip embedding groove 23, and an air hole 232 communicated with the outside is provided in the protruding portion 231.

[0143] In some embodiments, when the end of the liquid flow passage 22 is directly communicated with the outside, one end of the test strip embedding groove 23 is communicated with the liquid flow passage 22, and the other end of the test strip embedding groove 23 is hermetically arranged, so that when the mixed liquid enters the test strip embedding groove 23, it will be obstructed by a certain air pressure, preventing a large amount of the mixed liquid from surging into the test strip embedding groove 23, thereby facilitating the control of the suction volume.

[0144] In some embodiments, as Figure 7 shown, one end of the test strip embedding groove 23 is communicated with the liquid flow passage 22, and the end of the test strip embedding groove 23 is communicated with the outside.

[0145] In some embodiments, continuing to refer to Figure 7 shown, the ends of multiple test strip embedding grooves 23 can be communicated with the outside through the same channel.

[0146] In some embodiments, as Figure 13As shown, a protruding portion 231 is provided in each test strip embedding groove 23, and an air hole 232 communicating with the outside is provided in the protruding portion 231. Among them, the position height of the air hole 232 corresponds to the liquid level height when the test strip 4 is being sucked.

[0147] In some embodiments, with continued reference to Figure 13 As shown, at this time, the end position of the liquid flow channel 22 is higher than the position of its horizontal section 221, and the position height of the air hole 232 corresponds to the position height of the end of the liquid flow channel 22. Thus, after the mixed liquid flows into the horizontal section 221, it will not affect the sucking of the test strip 4 in the test strip embedding groove 23 near the end due to the flow impact, improving the stability when the test strip 4 is being sucked.

[0148] In some embodiments, a rubber plug is provided between each air hole 232 and the communication channel with the outside, so that the communication between the target air hole and the outside can be blocked by the rubber plug. At this time, under the action of the internal pressure, the mixed liquid will not enter the test strip embedding groove 23 where the blocked air hole 232 is located.

[0149] In some embodiments, the above rubber plug can also be replaced by setting a valve body, so that the communication state between the target air hole and the outside can be controlled by controlling the opening or closing of the corresponding valve body.

[0150] By setting the test strip embedding groove 23 to be in communication with the outside, the communication between the liquid flow channel 22 and the outside can be indirectly achieved, and at this time, it is also convenient for the smooth progress of the detection process.

[0151] As one application example, with reference to Figure 1 、 Figure 2 、 Figure 13 As shown, a narrow port structure 211 for achieving communication is provided between the liquid flow channel 22 and the reaction chamber 21.

[0152] In some embodiments, the end wall surface of the reaction chamber 21 connected to the narrow port structure 211 is inclined, and the lower end of the inclination communicates with the narrow port structure 211, thus further facilitating the outflow of the mixed liquid.

[0153] By providing the narrow port structure 211, it is convenient to control the outflow speed of the mixed liquid in the reaction chamber 21, so that the flow rate of the mixed liquid in the liquid flow channel 22 can be increased, making it more conducive for the mixed liquid to enter the liquid flow channel 22.

[0154] As an application example, the insertion direction of the swab 1 in the reaction chamber 21 is opposite to the direction in which the liquid flows from the reaction chamber 21 to the liquid flow channel 22;

[0155] Alternatively, the insertion direction of the swab 1 in the reaction chamber 21 is the same as the direction in which the liquid flows from the reaction chamber 21 to the liquid flow channel 22.

[0156] In some embodiments, the swab 1 is inserted from the top of the test cartridge 2 and pierces the liquid storage sac 3; after the sampling part 11 is mixed with the liquid at the bottom of the reaction chamber 21, the test cartridge 2 is inverted, so that the mixed liquid flows out from the liquid flow channel 22, and then subsequent tests are carried out. At this time, the connection between the liquid flow channel 22 and the reaction chamber 21 is arranged near the top of the test cartridge 2, refer to Figure 2 、 Figure 7 、 Figure 13 shown.

[0157] In some embodiments, the swab 1 is inserted from the top of the test cartridge 2 and pierces the liquid storage sac 3; after the sampling part 11 is mixed with the liquid at the bottom of the reaction chamber 21, the mixed liquid can flow out without inversion operation for subsequent tests. At this time, the connection between the liquid flow channel 22 and the reaction chamber 21 is arranged near the bottom of the test cartridge 2, refer to Figures 16 to 19 shown.

[0158] As an application example, as Figure 3 、 Figure 8 、 Figure 14 shown, the reaction chamber 21 has an opening 212 communicating with the side surface of the test cartridge 2, and the swab 1 is inserted from the opening 212 and forms a seal with the test cartridge 2.

[0159] In some embodiments, the cross-sectional shape of the opening 212 is the same as the cross-sectional shape of the reaction chamber 21.

[0160] In some embodiments, the cross-sectional shape of the opening 212 is different from the cross-sectional shape of the reaction chamber 21, so that the design of the internal space of the reaction chamber 21 can be more flexible.

[0161] In some embodiments, a sealing ring 12 is arranged between the outer side surface of the swab 1 and the inner wall surface of the opening 212, as Figure 3 、 Figure 8 、 Figure 14 shown.

[0162] In some embodiments, the cross-sectional shape of a part of the swab 1 is adapted to the cross-sectional shape of the opening 212, and the part of the swab 1 in contact with the opening 212 is made of a soft material, so as to form a seal through the interference fit between the swab 1 and the opening 212.

[0163] In some embodiments, as Figure 3 , Figure 14 shown, the liquid storage sac 3 is embedded at the opening 212.

[0164] In some embodiments, as Figure 8 , Figures 16 to 19 shown, the liquid storage sac 3 is embedded inside the reaction chamber 21.

[0165] By providing the opening 212, it is convenient to insert the swab 1 into the reaction chamber 21 and to realize the sealing function between the swab 1 and the test kit 2.

[0166] As an application example, referring to Figure 4 , Figure 9 , Figure 15 shown, the sampling part 11 is arranged in a conical shape.

[0167] By designing the shape and structure of the sampling part 11, it is convenient to improve the smoothness of the piercing action of the sampling part 11 on the liquid storage sac 3, and to make the outflow of the liquid in the liquid storage sac 3 smoother.

[0168] As an application example, a valve body mechanism is provided at the liquid inlet end of the liquid flow channel 22, and the valve body mechanism is used to control the communication between the liquid flow channel 22 and the reaction chamber 21.

[0169] In some embodiments, as Figure 16 shown, the valve body mechanism is arranged as an electric control valve 5. At this time, the electric control valve 5 is arranged at the communication part between the liquid flow channel 22 and the reaction chamber 21; when the electric control valve 5 is closed, the sampling part 11 and the liquid are in the mixing stage, and when the mixing is completed, the electric control valve 5 is opened to facilitate the outflow of the mixed liquid 31.

[0170] In some embodiments, as Figure 17 shown, the valve body mechanism is arranged as a mechanical valve 6. At this time, the mechanical valve 6 is arranged at the communication part between the liquid flow channel 22 and the reaction chamber 21, and a space for the displacement of the mechanical valve 6 is reserved in the reaction chamber 21. By controlling the movement of the mechanical valve 6, the communication between the liquid flow channel 22 and the reaction chamber 21 can be controlled.

[0171] Through the provided valve body mechanism, the flow state of the mixed liquid 31 in the liquid flow channel 22 can be controlled according to actual requirements.

[0172] As one application example, continue to refer to Figure 17 As shown, a sliding rod 13 is arranged in the swab 1, and the sliding rod 13 can move to abut against the valve body mechanism.

[0173] In some embodiments, the valve body mechanism is set as a mechanical valve 6 at this time.

[0174] In some embodiments, the sliding rod 13 is arranged in the swab 1. Before use, the end of the sliding rod 13 is received in the end of the swab 1. At this time, the swab 1 is normally inserted into the reaction chamber 21 and pierces the liquid storage sac 3. After the swab 1 is inserted in place, it is abutted against the mechanical valve 6; after the sample is mixed with the liquid, the sliding rod 13 is driven so that the end of the sliding rod 13 applies a force to the mechanical valve 6, thereby causing the mechanical valve 6 to displace, so that the mixed liquid 31 can flow into the liquid flow channel 22.

[0175] In some embodiments, the driving of the sliding rod 13 is set as manual pressing.

[0176] In some embodiments, the sliding rod 13 is controlled by arranging a micro motor.

[0177] By arranging the sliding rod 13, it is convenient to control the state of the valve body mechanism.

[0178] As one application example, refer to Figure 18 As shown, a control pump 7 is arranged at the liquid inlet end of the liquid flow channel 22, and the control pump 7 is used to control the connection between the liquid flow channel 22 and the reaction chamber 21.

[0179] In some embodiments, the control pump 7 is set as a peristaltic pump or a suction pump.

[0180] In some embodiments, when the control pump 7 is driven forward, the mixed liquid in the reaction chamber 21 is transported to the liquid flow channel 22; when the control pump 7 is driven in reverse, air is blown into the reaction chamber 21, thereby performing an elution operation on the mixed liquid 31.

[0181] By arranging the control pump 7, the flow of the mixed liquid 31 in the liquid flow channel 22 can be controlled according to actual requirements.

[0182] As one application example, refer to Figure 19As shown, a jet orifice 14 is provided on the reaction chamber 21 and / or the swab 1, and the position of the jet orifice 14 is higher than the liquid level height in the reaction chamber 21.

[0183] In some embodiments, the jet orifice 14 is provided on the inner wall of the reaction chamber 21.

[0184] In some embodiments, the swab 1 is hollow, and the jet orifice 14 is provided on the wall surface of the swab 1.

[0185] By providing the jet orifice 14, it is possible to facilitate the provision of internal pressure to promote the flow of the mixed liquid 31 in the liquid flow passage 22.

[0186] As an application example, as Figure 8 、 Figure 9 、 Figure 15 shown, the swab 1 includes a handle portion 15, and a vibrator 151 is provided inside the handle portion 15.

[0187] In some embodiments, the sampling portion 11 and the handle portion 15 are respectively provided at the front and rear ends of the swab 1, and the handle portion 15 is used to hold the swab 1.

[0188] In some embodiments, the vibrator 151 is set as a micro vibration motor.

[0189] By providing the vibrator 151, the swab 1 can have a certain vibration effect, thereby facilitating the improvement of the mixing reaction effect of the mixed liquid.

[0190] As an application example, as Figure 14 、 Figure 15 shown, the vibrator 151 is connected to a control switch 152, and the control switch 152 is convexly provided and forms a contact fit with the inner wall surface of the detection box 2.

[0191] In some embodiments, the control switch 152 protrudes from the outer peripheral surface of the handle portion 15, so that when the swab 1 is inserted or inserted in place, the control switch 152 is abutted by the inner wall surface of the detection box 2, thereby activating the control switch 152 to trigger the operation of the vibrator 151.

[0192] In some embodiments, as Figure 14 、 Figure 15 shown, the control switch 152 is concavely provided on the handle portion 15, and at this time, a part of the inner wall surface of the detection box 2 is convexly provided, so as to facilitate forming a fit with the control switch 152 during the insertion action of the swab 1 to activate the control switch 152.

[0193] By means of the provided control switch 152, and making the control switch 152 form a contact fit with the inner wall surface of the detection box 2, when the swab 1 is inserted in place, it will trigger the control switch 152, thereby starting the vibration mode.

[0194] As one application example, the vibrator 151 and the control switch 152 are arranged on a control circuit board 153, and an indicator light is arranged on the control circuit board 153.

[0195] In some embodiments, both the detection box 2 and the handle portion 15 are made of a light-transmitting material, and the indicator light is arranged at any position on the control circuit board 153.

[0196] In some embodiments, there is an association between the flashing condition of the indicator light and the operation of the vibrator 151. For example, when the control switch 152 is triggered and turned on, the vibrator 151 starts to operate, and the indicator light also flashes accordingly; when the vibration stirring operation within the set time is completed, the indicator light changes from the flashing state to the constantly-on state, thereby giving the user a more intuitive operation indication.

[0197] In some embodiments, a buzzer is arranged on the control circuit board 153. For example, when the vibration stirring operation within the set time is completed, a sound is emitted through the buzzer to inform the user.

[0198] In some embodiments, a button battery is installed on the control circuit board 153.

[0199] By means of the provided indicator light, the current operation state of the sample detection device can be prompted, preventing the user from making misoperations during the mixing process, thereby further improving the reliability of the device.

[0200] As one application example, as Figure 12 、 Figure 14 shown, a receiving cavity 26 for placing the swab 1 is arranged inside the detection box 2.

[0201] In some embodiments, as Figure 14 shown, the openings of the receiving cavity 26 and the reaction cavity 21 are arranged in opposite directions, so as to facilitate better utilization of the internal space of the detection box 2, and the overall structure is more compact.

[0202] By means of the provided receiving cavity 26, it is convenient to store and place the swab 1 on the detection box 2, making the overall storage of the device more convenient.

[0203] As an application example thereof, the test strip embedding groove 23 is provided on the same side of the reaction chamber 21;

[0204] Or, the test strip embedding grooves 23 are arranged on both sides of the reaction chamber 21.

[0205] In some embodiments, such as Figure 2 , Figure 13 , Figures 16 to 19 shown, a plurality of test strip embedding grooves 23 are provided, and the plurality of test strip embedding grooves 23 are provided on the same side of the reaction chamber 21; in this structural form, it is convenient to reduce the inversion operation of the detection box 2, and after the mixed liquid flows into the liquid flow channel 22, the influence of different contact times between the detection test strip 4 and the mixed liquid can be reduced.

[0206] In some embodiments, three test strip embedding grooves 23 are provided.

[0207] In some embodiments, such as Figure 7 shown, four test strip embedding grooves 23 are provided, and the four test strip embedding grooves 23 are symmetrically arranged on both sides of the reaction chamber 21; in this structural form, the entire sample detection device can have better symmetry.

[0208] The above is only the specific implementation manner of the present application and is not used to limit the protection scope of the present application. For those skilled in the art, the present application can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application. Any person skilled in the art can easily think of changes or replacements within the technical scope disclosed in the present application, and they should also be covered by the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

[0209] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or further includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including one..." does not exclude the existence of additional identical elements in the process, method, article or device including the element.

Claims

1. A sample detection device, characterized in that, Including: A swab, the swab including a sampling part; A detection cassette, the detection cassette being provided with a reaction cavity, a liquid flow channel and a test strip embedding groove; A liquid storage sac is arranged in the reaction cavity, the swab can be inserted and arranged in the reaction cavity, and the sampling part pierces through the liquid storage sac; One end of the liquid flow channel is communicated with the reaction cavity, the test strip embedding groove is communicated with the liquid flow channel, and the end of the liquid flow channel is communicated with the outside; When the test strip embedding groove is placed vertically, the position height of the end of the liquid flow channel is higher than the position height of the connection between the test strip embedding groove and the liquid flow channel; or, the position height of the end of the liquid flow channel is lower than the position height of the connection between the test strip embedding groove and the liquid flow channel, and a bending section is arranged between the end of the liquid flow channel and the connection end of the test strip embedding groove and the liquid flow channel, and at least part of the position height of the bending section is higher than the position height of the connection between the test strip embedding groove and the liquid flow channel.

2. The sample detection device according to claim 1, wherein There is one test strip embedding groove; Or, there are multiple test strip embedding grooves, and the multiple test strip embedding grooves are arranged side by side, and the liquid flow channel is located at the same end of the multiple test strip embedding grooves.

3. The sample detection device according to claim 2, wherein, A detection test strip is arranged in the test strip embedding groove.

4. The sample detection device according to any one of claims 1 to 3, characterized in that, A result observation area is arranged on the detection cassette, and at least part of the test strip embedding groove overlaps with the result observation area.

5. The sample detection device according to claim 1, wherein, Along the conveying direction of the liquid flow channel, the bending section includes a first diameter-width section and a second diameter-width section, and the diameter-width of the first diameter-width section is greater than the diameter-width of the second diameter-width section.

6. The sample detection device according to claim 1 or 5, characterized in that, An air flow channel is arranged on the detection cassette, one end of the air flow channel is communicated with the reaction cavity, and the other end of the air flow channel is communicated with the outside; When the test strip embedding groove is placed vertically, the position height of the air flow channel is higher than the position height of the connection between the liquid flow channel and the reaction cavity.

7. The sample detection device according to claim 6, characterized in that, The air flow channel is arranged in a bending manner.

8. The sample detection device according to claim 4, wherein, One end of the test strip embedding groove is communicated with the liquid flow channel, and the other end of the test strip embedding groove is communicated with the outside; Or, a protruding part is arranged in the test strip embedding groove, and an air hole communicated with the outside is arranged in the protruding part.

9. The sample detection device according to claim 6, wherein, A narrow port structure for realizing communication is arranged between the liquid flow channel and the reaction cavity.

10. The sample detection device according to claim 1 or 9, characterized in that, The insertion direction of the swab in the reaction cavity is opposite to the direction in which the liquid flows from the reaction cavity to the liquid flow channel; Or, the insertion direction of the swab in the reaction cavity is the same as the direction in which the liquid flows from the reaction cavity to the liquid flow channel.

11. The sample detection device according to claim 10, wherein, The reaction cavity has an opening communicated with the side surface of the detection cassette, and the swab is inserted from the opening and forms a seal with the detection cassette.

12. The sample detection device according to claim 11, wherein, The sampling part is arranged in a conical shape.

13. The sample detection device according to claim 1, wherein A valve body mechanism is arranged at the liquid inlet end of the liquid flow channel, and the valve body mechanism is used to control the communication between the liquid flow channel and the reaction cavity.

14. The sample detection device according to claim 13, wherein A sliding rod is arranged in the swab, and the sliding rod can move to abut against the valve body mechanism.

15. The sample detection device according to claim 1, wherein A control pump is arranged at the liquid inlet end of the liquid flow channel, and the control pump is used to control the communication between the liquid flow channel and the reaction cavity.

16. The sample detection device according to claim 1, wherein, An air jet opening is provided on the reaction chamber and / or the swab, and the position of the air jet opening is higher than the liquid level height in the reaction chamber.

17. The sample detection device according to claim 1, characterized in that The swab includes a handle portion, and a vibrator is provided inside the handle portion.

18. The sample detection device according to claim 17, characterized in that, The vibrator is connected to a control switch, and the control switch is convexly provided and forms a contact fit with the inner wall surface of the detection box.

19. The sample detection device according to claim 18, characterized in that, The vibrator and the control switch are arranged on a control circuit board, and an indicator light is provided on the control circuit board.

20. The sample detection device according to any one of claims 1, 17 - 19, characterized in that, A receiving cavity for placing the swab is provided in the detection box.

21. The sample detection device according to claim 1, wherein The test strip embedding groove is provided on the same side of the reaction chamber; Or, the test strip embedding grooves are arranged on both sides of the reaction chamber.

Images