A medicated thread for traditional Chinese medicine thread moxibustion and its preparation method

Abstract

The present invention relates to a medicinal thread for traditional Chinese medicine thread moxibustion and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. The medicinal thread provided by the present invention is treated with a specific medicinal liquid, so that the medicinal thread combines the medicinal effects of a variety of Chinese medicinal materials, and each component synergistically enhances the effect. When using the medicinal thread, the medicinal effect can be transmitted to the lesion site by stimulating acupoints, which can effectively reduce the inflammatory reaction, promote blood circulation at the same time, accelerate the absorption and dissipation of stasis, relieve swelling and pain, regulate the body function by regulating the flow of qi and blood, play a role in strengthening the healthy qi and consolidating the root, and promote the self-repair and recovery of the body.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and relates to a medicinal thread for traditional Chinese medicine thread moxibustion and a preparation method thereof. Background Technique

[0002] As one of the oldest and most important therapies in traditional Chinese medicine, moxibustion, as an important method for preventing and treating diseases, has been inherited and carried forward by humans. Currently, so-called moxibustion around the world generally refers to moxa moxibustion, which uses moxa sticks made by burning mugwort leaves. The heat generated stimulates human acupoints or specific parts, and adjusts the disordered physiological and biochemical functions of the human body by stimulating the activities of meridian qi, so as to achieve the purpose of preventing and treating diseases.

[0003] The common moxibustion is moxa moxibustion. However, the moxibustion time of moxa moxibustion is long, and it takes more than twenty minutes of moxibustion for each acupoint to have an effect. Moreover, many people find it difficult to bear the moxa smoke generated by the moxa stick, which also has an impact on the environment. In addition, moxa moxibustion generally can only use the warm moxibustion method and cannot be directly in contact with the skin, otherwise it will burn the skin, and obvious moxibustion marks will also appear on the moxibusted skin. Therefore, it is difficult to directly perform moxa moxibustion, resulting in poor effects. The "medicinal thread moxibustion" therapy, as a combination of rush moxibustion and acupuncture, uses drugs that are irritating to the skin to moxibust on acupoints or affected areas (Ashi points), so that the local skin naturally congests, flushes or forms moxibustion blisters, thereby treating diseases. It mainly exerts the therapeutic effect through the transdermal method to make the drug and acupoints interact with each other. Compared with moxa moxibustion, it has a faster effect, smaller marks and is convenient to carry, and is more and more widely used in traditional Chinese medicine treatment. Summary of the Invention

[0004] The purpose of the present invention is to provide a medicinal thread for traditional Chinese medicine thread moxibustion and a preparation method thereof. The present invention uses a variety of traditional Chinese medicine components to prepare a medicinal liquid. When preparing the medicinal liquid, the components are processed and added step by step, effectively extracting and utilizing the effective components in traditional Chinese medicine, so that the medicinal thread combines the medicinal effects of a variety of traditional Chinese medicinal materials. For example, realgar, isatis root, folium isatidis, etc. exert the effects of clearing heat and detoxifying, dragon's blood, salvia miltiorrhiza, safflower, etc. exert the effects of promoting blood circulation and removing blood stasis, ampelopsis japonica, frankincense, borneol, etc. exert the effects of detumescence and pain relief, etc. Each component synergistically enhances the effect. By stimulating acupoints with the medicinal thread, the medicinal effect is transmitted to the lesion site, which can effectively reduce the inflammatory reaction, promote blood circulation at the same time, accelerate the absorption and dissipation of blood stasis, relieve swelling and pain, regulate the body function by regulating the flow of qi and blood, play the role of strengthening the healthy qi and consolidating the root, and promote the body's self-repair and recovery.

[0005] The purpose of the present invention can be achieved by the following technical solutions:

[0006] A preparation method of a medicinal thread for traditional Chinese medicine thread moxibustion, the preparation method of the medicinal thread is: soak ramie thread in the medicinal liquid for 5 - 10 weeks, take it out and dry it in the sun to obtain the medicinal thread.

[0007] Furthermore, the ramie thread is prepared by soaking the collected ramie branches in clean water for one day and night and then removing the green skin. The obtained ramie silk is twisted into a single strand of half a millimeter thick ramie thread, and two strands are twisted into a strand of 1 millimeter.

[0008] Furthermore, the preparation method of the medicinal solution is:

[0009] (1) Mixing the powder material A and the ethanol solution, stirring, and obtaining a mixture 1;

[0010] (2) adding powder B to mixture 1 and stirring to obtain mixture 2;

[0011] (3) Add concentrated liquid medicine to mixed material 2, stir, keep warm, cool to room temperature, and place in the dark for 39-59 days to obtain liquid medicine.

[0012] Furthermore, the raw materials of the mixing material 1 in step (1) include 5.6-8.1wt% of the medicinal powder material A and the balance of ethanol solution; the mass concentration of the ethanol solution is 64-86wt%; the stirring speed and time are 50-150rmp and 20-30min respectively.

[0013] Furthermore, the medicinal powder A is obtained by mixing 210-230 parts by weight of realgar, 210-230 parts by weight of musk, 100-110 parts by weight of red ochre, 60-66 parts by weight of dragon's blood, 70-80 parts by weight of frankincense, 100-120 parts by weight of borneol, and 40-50 parts by weight of indigo. The mixture is then crushed and passed through an 80-120 mesh sieve.

[0014] Furthermore, the mass of the medicinal powder material B in step (2) accounts for 2.3-5wt% of the mixed material 2; the rotation speed and time of the stirring step are 20-40rmp and 1-2h respectively.

[0015] Furthermore, the medicinal powder B is composed of 190-210 parts by weight of white ampelopsis, 200-220 parts by weight of sanguisorba officinalis, 160-180 parts by weight of atractylodes, 205-215 parts by weight of phellodendron, 168-190 parts by weight of gentian, 190-200 parts by weight of scutellaria, 230-250 parts by weight of rehmannia, 110-130 parts by weight of liquorice, 200-210 parts by weight of astragalus, 190- The invention discloses a method for preparing a powdered product by mixing 200 parts by weight of Polygonum multiflorum, 180-190 parts by weight of Salvia miltiorrhiza, 150-170 parts by weight of Bletilla striata, 120-130 parts by weight of Cinnamomum cassia, 140-150 parts by weight of Trillium gracile, 205-215 parts by weight of Angelica sinensis, 140-150 parts by weight of Curcuma zedoaria, 160-164 parts by weight of Saposhnikovia divaricata and 200-210 parts by weight of Isatis root, and then grinding the mixture and passing through a 100-140 mesh sieve to obtain the powdered product.

[0016] Further, the mass of the concentrated medicinal liquid in step (3) accounts for 1.5-3.7 wt% of the medicinal liquid; the parameters of the stirring step are: the stirring temperature is 40-60 °C, the stirring speed is 100-200 rmp, and the stirring time is 15-35 min; the heat preservation time is 1-3 h.

[0017] Further, the preparation method of the concentrated medicinal liquid is as follows:

[0018] After washing the raw materials, put them into a container, pour in deionized water with a volume three times that of the raw materials, decoct over a slow fire for 1-2 h, pour out the decoction liquid, repeat the decoction three times, combine the three decoction liquids, concentrate to 1 / 3 of the original volume, then add an 87-95 wt% ethanol solution to the concentrated liquid until the alcohol content reaches 73-78 wt%, let it stand for precipitation for 24 h, filter, and then concentrate to 1 / 3 of the filtrate to obtain the concentrated medicinal liquid.

[0019] Further, the raw materials include 160-170 parts of perilla leaves, 150-160 parts of schizonepeta, 210-220 parts of isatis indigotica, 120-130 parts of mentha haplocalyx, 200-210 parts of portulaca oleracea, 205-215 parts of dandelion, 190-200 parts of viola philippica, 210-220 parts of honeysuckle, 160-170 parts of andrographis paniculata, 70-80 parts of safflower, and 180-190 parts of scutellaria barbata by weight.

[0020] Advantages of the present invention:

[0021] The present invention prepares a medicinal liquid using a variety of traditional Chinese medicine components, and processes and adds the components step by step during the preparation of the medicinal liquid, effectively extracting and utilizing the active ingredients in the traditional Chinese medicine, so that the medicated thread combines the medicinal effects of a variety of traditional Chinese medicine materials. For example, realgar, isatis root, isatis indigotica, etc. play the role of clearing heat and detoxifying; dragon's blood, salvia miltiorrhiza, safflower, etc. play the role of promoting blood circulation and removing stasis; ampelopsis japonica, frankincense, borneol, etc. play the role of detumescence and pain relief, etc. Each component synergistically enhances the effect. By stimulating acupoints with the medicated thread, the medicinal effect is transmitted to the lesion site, which can effectively reduce the inflammatory reaction, promote blood circulation at the same time, accelerate the absorption and dissipation of stasis, relieve swelling and pain, regulate the body function by regulating the flow of qi and blood, play the role of strengthening the healthy qi and consolidating the root, and promote the self-repair and recovery of the body. Specific embodiments

[0022] To further elaborate on the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the following examples are provided to illustrate in detail the specific embodiments, structures, features and their effects of the present invention.

[0023] Example 1

[0024] A preparation method of a medicated thread for traditional Chinese medicine thread moxibustion. The preparation method of the medicated thread in this example is: soak the ramie thread in the medicinal liquid for 5 weeks, take it out and dry it in the sun to obtain the medicated thread.

[0025] The ramie thread of this embodiment is obtained by soaking the collected ramie branches in water for one day and night and then removing the green skin. The obtained ramie silk is twisted into a single strand of half a millimeter thick ramie thread, and two strands are twisted into a 1 mm thick strand.

[0026] The preparation method of the medicinal solution of this embodiment is:

[0027] (1) Mixing the powder material A and the ethanol solution, stirring, and obtaining a mixture 1;

[0028] (2) adding powder B to mixture 1 and stirring to obtain mixture 2;

[0029] (3) Add concentrated medicinal solution to mixed material 2, stir, keep warm, cool to room temperature, and place in the dark for 39 days to obtain medicinal solution.

[0030] In step (1), the raw materials of the mixture 1 of this embodiment include 5.6wt% of the medicinal powder A and the balance of ethanol solution; the mass concentration of the ethanol solution of this embodiment is 64wt%; the stirring speed and time of this embodiment are 50rmp and 20min respectively.

[0031] The medicinal powder A of this embodiment is obtained by mixing 210 parts by weight of realgar, 210 parts by weight of musk, 100 parts by weight of red ochre, 60 parts by weight of dragon's blood, 70 parts by weight of frankincense, 100 parts by weight of borneol, and 40 parts by weight of indigo, and then grinding and passing through an 80-mesh sieve.

[0032] In step (2), the mass of the medicinal powder B of this embodiment accounts for 2.3 wt% of the mixed material 2; the rotation speed and time of the stirring step of this embodiment are 20 rpm and 1 h, respectively.

[0033] The medicinal powder B of the present embodiment is prepared by mixing 190 parts by weight of Radix Bletillae, 200 parts by weight of Radix Sanguisorbae, 160 parts by weight of Rhizoma Atractylodis Macrocephalae, 205 parts by weight of Cortex Phellodendri, 168 parts by weight of Gentiana Scabra, 190 parts by weight of Radix Scutellariae, 230 parts by weight of Radix Rehmanniae, 110 parts by weight of Radix Glycyrrhizae, 200 parts by weight of Radix Astragali, 190 parts by weight of Polygonum Multiflorum, 180 parts by weight of Radix Salviae Miltiorrhizae, 150 parts by weight of Rhizoma Bletillae, 120 parts by weight of Rhizoma Cinnamomi, 140 parts by weight of Rhizoma Sparganii, 205 parts by weight of Radix Angelicae Sinensis, 140 parts by weight of Rhizoma Curcumae, 160 parts by weight of Radix Saposhnikoviae and 200 parts by weight of Radix Isatidis, and then pulverizing the mixture and passing through a 100 mesh sieve to obtain the medicinal powder B.

[0034] The mass of the concentrated medicinal liquid in step (3) of this embodiment accounts for 1.5wt% of the medicinal liquid; the parameters of the stirring step of this embodiment are: stirring temperature is 40°C, stirring speed is 100rmp, stirring time is 15min; the insulation time of this embodiment is 1h.

[0035] The preparation method of the concentrated medicinal solution of this embodiment is:

[0036] After washing the raw materials, put them into a container, pour in deionized water 3 times the volume of the raw materials, simmer for 1 hour, pour out the decoction, repeat the decoction three times, combine the three decoctions, concentrate to 1 / 3 of the original volume, add 87wt% ethanol solution to the concentrate until the alcohol content reaches 73wt%, let it stand and settle for 24 hours, filter, and then concentrate to 1 / 3 of the filtrate to obtain a concentrated medicinal solution.

[0037] The raw materials of this embodiment include 160 parts of perilla leaves, 150 parts of schizonepeta, 210 parts of isatis indigotica, 120 parts of mint, 200 parts of purslane, 205 parts of dandelions, 190 parts of viola yedoensis, 210 parts of honeysuckle, 160 parts of andrographis paniculata, 70 parts of safflower, and 180 parts of Scutellaria barbata.

[0038] Example 2

[0039] A method for preparing medicinal thread for traditional Chinese medicine moxibustion. The preparation method of the medicinal thread in this embodiment is as follows: ramie thread is soaked in medicinal liquid for 10 weeks, taken out and dried in the sun to obtain the medicinal thread.

[0040] The ramie thread of this embodiment is obtained by soaking the collected ramie branches in water for one day and night and then removing the green skin. The obtained ramie silk is twisted into a single strand of half a millimeter thick ramie thread, and two strands are twisted into a 1 mm thick strand.

[0041] The preparation method of the medicinal solution of this embodiment is:

[0042] (1) Mixing the powder material A and the ethanol solution, stirring, and obtaining a mixture 1;

[0043] (2) adding powder B to mixture 1 and stirring to obtain mixture 2;

[0044] (3) Add concentrated liquid medicine to mixed material 2, stir, keep warm, cool to room temperature, and place in the dark for 59 days to obtain liquid medicine.

[0045] In step (1), the raw materials of the mixture 1 of this embodiment include 8.1wt% of the medicinal powder A and the balance of ethanol solution; the mass concentration of the ethanol solution of this embodiment is 86wt%; the stirring speed and time of this embodiment are 150rmp and 30min respectively.

[0046] The medicinal powder A of this embodiment is obtained by mixing 230 parts by weight of realgar, 230 parts by weight of musk, 110 parts by weight of red ochre, 66 parts by weight of dragon's blood, 80 parts by weight of frankincense, 120 parts by weight of borneol, and 50 parts by weight of indigo, and then grinding and passing through a 120-mesh sieve.

[0047] In step (2), the mass of the medicinal powder B of this embodiment accounts for 5wt% of the mixed material 2; the speed and time of the stirring step of this embodiment are 40 rpm and 2 h, respectively.

[0048] The medicinal powder B of the present embodiment is mixed by 210 weight parts of Bletilla striata, 220 weight parts of Sanguisorba officinalis, 180 weight parts of Atractylodes lancea, 215 weight parts of Phellodendron chinense, 190 weight parts of Gentiana scabra, 200 weight parts of Scutellaria baicalensis, 250 weight parts of Rehmannia glutinosa, 130 weight parts of Licorice, 210 weight parts of Astragalus membranaceus, 200 weight parts of Polygonum multiflorum, 190 weight parts of Salvia miltiorrhiza, 170 weight parts of Bletilla striata, 130 weight parts of Cinnamomum cassiae, 150 weight parts of Sparganium, 215 weight parts of Angelica sinensis, 150 weight parts of Curcuma zedoaria, 164 weight parts of Saposhnikovia divaricata and 210 weight parts of Radix Isatidis, and then pulverized and passed through a 140 mesh sieve to obtain.

[0049] The mass of the concentrated medicinal liquid in step (3) of this embodiment accounts for 3.7wt% of the medicinal liquid; the parameters of the stirring step of this embodiment are: stirring temperature is 60°C, stirring speed is 200rmp, stirring time is 35min; the insulation time of this embodiment is 3h.

[0050] The preparation method of the concentrated medicinal solution of this embodiment is:

[0051] After washing the raw materials, put them into a container, pour in deionized water 3 times the volume of the raw materials, simmer for 2 hours, pour out the decoction, repeat the decoction three times, combine the three decoctions, concentrate to 1 / 3 of the original volume, add 95wt% ethanol solution to the concentrate until the alcohol content reaches 78wt%, let it stand and settle for 24 hours, filter, and then concentrate to 1 / 3 of the filtrate to obtain a concentrated medicinal solution.

[0052] The raw materials of this embodiment include 170 parts of perilla leaves, 160 parts of schizonepeta, 220 parts of isatis indigotica, 130 parts of mint, 210 parts of purslane, 215 parts of dandelions, 200 parts of viola yedoensis, 220 parts of honeysuckle, 170 parts of andrographis paniculata, 80 parts of safflower, and 190 parts of Scutellaria barbata.

[0053] Example 3

[0054] A method for preparing medicinal thread for traditional Chinese medicine moxibustion. The preparation method of the medicinal thread in this embodiment is as follows: ramie thread is soaked in a medicinal solution for 7.5 weeks, taken out and dried in the sun to obtain the medicinal thread.

[0055] The ramie thread of this embodiment is obtained by soaking the collected ramie branches in water for one day and night and then removing the green skin. The obtained ramie silk is twisted into a single strand of half a millimeter thick ramie thread, and two strands are twisted into a 1 mm thick strand.

[0056] The preparation method of the medicinal solution of this embodiment is:

[0057] (1) Mixing the powder material A and the ethanol solution, stirring, and obtaining a mixture 1;

[0058] (2) Add medicinal powder B to Mixing Material 1 and stir to obtain Mixing Material 2;

[0059] (3) Add concentrated medicinal liquid to Mixing Material 2, stir, keep warm, let it cool to room temperature, and then place it in the dark for 49 days to obtain the medicinal liquid.

[0060] In step (1), the raw materials of Mixing Material 1 in this example include 6.85 wt% of medicinal powder A and the balance of ethanol solution; the mass concentration of the ethanol solution in this example is 75 wt%; the rotation speed and time of stirring in this example are 100 rmp and 25 min respectively.

[0061] Medicinal powder A in this example is obtained by mixing 220 parts by weight of realgar, 220 parts by weight of musk, 105 parts by weight of halloysite, 63 parts by weight of dragon's blood, 75 parts by weight of frankincense, 110 parts by weight of borneol, 45 parts by weight of indigo naturalis, and then pulverizing and passing through a 100-mesh sieve.

[0062] In step (2), the mass of medicinal powder B in this example accounts for 3.65 wt% of Mixing Material 2; the rotation speed and time of the stirring step in this example are 30 rmp and 1.5 h respectively.

[0063] Medicinal powder B in this example is obtained by mixing 200 parts by weight of ampelopsis japonica, 210 parts by weight of sanguisorba officinalis, 170 parts by weight of atractylodes lancea, 210 parts by weight of phellodendron amurense, 179 parts by weight of gentiana scabra, 195 parts by weight of scutellaria baicalensis, 240 parts by weight of rehmannia glutinosa, 120 parts by weight of liquorice, 205 parts by weight of astragalus membranaceus, 195 parts by weight of polygonum multiflorum, 185 parts by weight of salvia miltiorrhiza, 160 parts by weight of bletilla striata, 125 parts by weight of cinnamon twig, 145 parts by weight of sparganium stoloniferum, 210 parts by weight of angelica sinensis, 145 parts by weight of curcuma zedoaria, 162 parts by weight of ledebouriella seseloides, and 205 parts by weight of isatis root, and then pulverizing and passing through a 120-mesh sieve.

[0064] In step (3), the mass of the concentrated medicinal liquid in this example accounts for 2.6 wt% of the medicinal liquid; the parameters of the stirring step in this example are: the stirring temperature is 50 °C, the stirring speed is 150 rmp, and the stirring time is 25 min; the heat preservation time in this example is 2 h.

[0065] The preparation method of the concentrated medicinal liquid in this example is as follows:

[0066] Wash the raw materials, put them into a container, pour in deionized water with a volume three times that of the raw materials, decoct with slow fire for 1.5 h, pour out the decoction liquid, repeat decocting three times, combine the three decoction liquids, concentrate to 1 / 3 of the original volume, then add 91 wt% ethanol solution to the concentrated liquid until the alcohol content reaches 75 wt%, let it stand for precipitation for 24 h, filter, and then concentrate to 1 / 3 of the filtrate to obtain the concentrated medicinal liquid.

[0067] The raw materials of this embodiment include 165 parts of perilla leaves, 155 parts of schizonepeta, 215 parts of folium isatidis, 125 parts of wild mint, 205 parts of purslane, 210 parts of dandelion, 195 parts of viola yedoensis, 205 parts of honeysuckle, 165 parts of andrographis paniculata, 75 parts of safflower, and 185 parts of scutellaria barbata by weight.

[0068] Comparative Example 1

[0069] On the basis of Example 3, lithospermum in medicinal powder A was removed and replaced with dragon's blood of equal weight, and the others were the same as Example 3.

[0070] Comparative Example 2

[0071] On the basis of Example 3, dragon's blood in medicinal powder A was removed and replaced with frankincense of equal weight, and the others were the same as Example 3.

[0072] Comparative Example 3

[0073] On the basis of Example 3, frankincense in medicinal powder A was removed and replaced with lithospermum of equal weight, and the others were the same as Example 3.

[0074] Comparative Example 4

[0075] On the basis of Example 3, sparganium in medicinal powder B was removed and replaced with cassia twig of equal weight, and the others were the same as Example 3.

[0076] Comparative Example 5

[0077] On the basis of Example 3, cassia twig in medicinal powder B was removed and replaced with zedoary of equal weight, and the others were the same as Example 3.

[0078] Comparative Example 6

[0079] On the basis of Example 3, zedoary in medicinal powder B was removed and replaced with sparganium of equal weight, and the others were the same as Example 3.

[0080] Comparative Example 7

[0081] On the basis of Example 3, safflower in the raw materials of concentrated medicinal liquid was removed and replaced with dandelion of equal weight, and the others were the same as Example 3.

[0082] Comparative Example 8

[0083] On the basis of Example 3, dandelion in the raw materials of concentrated medicinal liquid was removed and replaced with folium isatidis of equal weight, and the others were the same as Example 3.

[0084] Comparative Example 9

[0085] On the basis of Example 3, folium isatidis in the raw materials of concentrated medicinal liquid was removed and replaced with safflower of equal weight, and the others were the same as Example 3.

[0086] Comparative Example 10

[0087] Based on Example 3, while keeping other conditions the same, the preparation steps of the medicinal liquid were changed to:

[0088] (1) After mixing medicinal powder A, medicinal powder B and the ethanol solution, stir to obtain mixture one;

[0089] (2) Add the concentrated medicinal liquid to mixture one, stir, keep warm, let it cool to room temperature, and then place it in the dark for 49 days to obtain the medicinal liquid.

[0090] Comparative Example 11

[0091] Based on Example 3, while keeping other conditions the same, the preparation steps of the medicinal liquid were changed to:

[0092] (1) After mixing medicinal powder A and the ethanol solution, obtain mixture one;

[0093] (2) Add medicinal powder B to mixture one to obtain mixture two;

[0094] (3) Add the concentrated medicinal liquid to mixture two, place it in the dark for 49 days to obtain the medicinal liquid.

[0095] Sixty patients were selected, aged between 18 and 65 years old, with an equal number of males and females, meeting the diagnostic criteria for neck and shoulder, and low back and leg pain, and excluding patients with lumbar tuberculosis, tumors, patients with severe internal diseases, mental diseases, infectious diseases, women during pregnancy, or those using other drugs that may affect the determination of efficacy, patients with obvious skin lesions or scarring on the lower back and skin, and those who are participating in other clinical trials. All patients in this trial agreed to participate and signed the informed consent form, and were able to adhere to the full course of treatment and follow-up as required.

[0096] Using the medicated threads prepared in Examples 1 - 3 and Comparative Examples 1 - 11, the usage method is as follows: After igniting the medicated thread, blow out the open flame, use the bead flame at the end of the thread to follow the meridian to be moxibusted, stay at the acupoint, about 0.5 mm away from the acupoint, blow towards the flame head with the qi of the dantian, and then quickly leave. Perform this technique on each acupoint on the meridian in turn until the bead flame is completely extinguished. The usage period is once a day, with seven days as one course of treatment, two courses of treatment as one treatment cycle, and the interval between courses is three days. Follow-up is conducted one week after the end of treatment, and pain assessment is carried out according to the international pain conventional ten-level classification method. The average rating is recorded as shown in Table 1.

[0097] The pain assessment is divided into levels 0 - 10. Level 0 means no pain, level 1 means occasional soreness, level 2 means mild pain, level 3 means moderate pain, level 4 means the pain has a certain impact on life, level 5 means painkillers are needed, level 6 means severe pain, level 7 means narcotic painkillers are needed, level 8 means seriously affecting life, level 9 means accompanied by other symptoms, and level 10 means seriously affecting life, accompanied by other symptoms or a passive body position.

[0098] Table 1

[0099]

[0100]

[0101] As can be seen from Table 1, the medicated threads prepared in Examples 1 - 3 of the present invention can effectively relieve the pain of patients. The pain starts to significantly reduce on the third day of treatment, and after the end of the cycle treatment, it can return to a painless state or occasional soreness. In Comparative Examples 1 - 9, the components of the liquid medicine are replaced, and the synergistic effect of each component in the present invention cannot be achieved, so the treatment effect is weakened; in Comparative Examples 10 and 11, the preparation steps of the liquid medicine are changed, lacking step - by - step treatment or stirring assistance, etc., and the extraction of the effective components of traditional Chinese medicine is not as good as that in the examples, so the short - term effect is not as good as that in the examples. In addition, no infection at the moxibustion points occurred during and after the treatment process, the pigmentation decreased after the treatment ended, and most of the spots gradually faded and disappeared over time.

[0102] The above - mentioned are only the preferred embodiments of the present invention, and do not impose any form of limitation on the present invention. Although the present invention has been disclosed above with preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art, without departing from the scope of the technical solution of the present invention, can make some changes or modifications to the above - disclosed technical content to form equivalent embodiments of equivalent changes. However, as long as it does not depart from the content of the technical solution of the present invention, any brief modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A preparation method of a medicinal thread for traditional Chinese medicine thread moxibustion, characterized in that: The preparation method of the medicinal thread is as follows: soaking ramie thread in the medicinal solution for 5-10 weeks, taking it out and drying it in the sun to obtain the medicinal thread; The preparation method of the medicinal solution is: (1) Mixing powder material A and ethanol solution, stirring to obtain mixed material 1; the powder material A is prepared by mixing 210-230 parts by weight of realgar, 210-230 parts by weight of musk, 100-110 parts by weight of red ochre, 60-66 parts by weight of dragon's blood, 70-80 parts by weight of frankincense, 100-120 parts by weight of borneol, and 40-50 parts by weight of indigo, and then grinding and passing through an 80-120 mesh sieve; (2) Adding powder material B to the mixture 1 and stirring to obtain the mixture 2; the powder material B is composed of 190-210 parts by weight of white mulberry, 200-220 parts by weight of sanguisorba officinalis, 160-180 parts by weight of atractylodes, 205-215 parts by weight of phellodendron, 168-190 parts by weight of gentian, 190-200 parts by weight of scutellaria, 230-250 parts by weight of rehmannia, 110-130 parts by weight of liquorice, 200-210 parts by weight of cinnamon bark, 100-130 parts by weight of licorice, 200-210 parts by weight of cinnamon bark, 100-130 parts by weight of scutellaria, 200-210 parts by weight of ginseng, 100-13 ... parts by weight of Astragalus, 190-200 parts by weight of Polygonum multiflorum, 180-190 parts by weight of Salvia miltiorrhiza, 150-170 parts by weight of Bletilla striata, 120-130 parts by weight of Cinnamomum cassia, 140-150 parts by weight of Trigonum spicatum, 205-215 parts by weight of Angelica sinensis, 140-150 parts by weight of Curcuma zedoaria, 160-164 parts by weight of Saposhnikovia divaricata, and 200-210 parts by weight of Isatis root, and then pulverized and passed through a 100-140 mesh sieve to obtain a product; (3) Add concentrated liquid medicine to the mixture 2, stir, keep warm, cool to room temperature, and place in the dark for 39-59 days to obtain liquid medicine; The preparation method of the concentrated medicinal solution is: After washing the raw materials, place them in a container, pour in deionized water 3 times the volume of the raw materials, simmer for 1-2 hours, pour out the decoction, repeat the decoction three times, combine the three decoctions, concentrate to 1 / 3 of the original volume, add 87-95wt% ethanol solution to the concentrate until the alcohol content reaches 73-78wt%, let it stand for 24 hours, filter, and then concentrate to 1 / 3 of the filtrate to obtain a concentrated medicinal solution; The raw materials include, by weight, 160-170 parts of perilla leaves, 150-160 parts of schizonepeta, 210-220 parts of isatis indigotica, 120-130 parts of mint, 200-210 parts of purslane, 205-215 parts of dandelions, 190-200 parts of viola yedoensis, 210-220 parts of honeysuckle, 160-170 parts of andrographis paniculata, 70-80 parts of safflower, and 180-190 parts of scutellaria barbata.

2. The preparation method of a medicated thread for traditional Chinese medicine thread moxibustion according to claim 1, characterized in that: The ramie thread is prepared by soaking collected ramie branches in clean water for one day and night and then removing the green skin. The obtained ramie fibers are twisted into a single strand of half a millimeter thick ramie thread, and two strands are twisted into a strand of 1 millimeter thick.

3. The preparation method of a medicinal thread for traditional Chinese medicine thread moxibustion according to claim 1, characterized in that: The raw materials of the mixing material 1 in step (1) include 5.6-8.1wt% of the medicinal powder material A and the balance of ethanol solution; the mass concentration of the ethanol solution is 64-86wt%; the speed and time of the stirring are 50-150rmp and 20-30min respectively.

4. The preparation method of a medicated thread for traditional Chinese medicine thread moxibustion according to claim 1, characterized in that: The mass of the medicinal powder B described in step (2) accounts for 2.3 - 5 wt% of the second mixture; the rotation speed and time of the stirring step are 20 - 40 rmp and 1 - 2 h respectively.

5. The preparation method of a medicated thread for traditional Chinese medicine thread moxibustion according to claim 1, characterized in that: The mass of the concentrated medicinal liquid described in step (3) accounts for 1.5 - 3.7 wt% of the medicinal liquid; the parameters of the stirring step are: the stirring temperature is 40 - 60 °C, the stirring speed is 100 - 200 rmp, and the stirring time is 15 - 35 min; the heat preservation time is 1 - 3 h.

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