Syringe operating device and sample processing apparatus
By designing the syringe operating device, using the cylinder jaw assembly and piston plug-in assembly to cooperate with the robot, the syringe operation is automated, and the problems of cumbersome steps and low space utilization in the existing technology are solved, and efficiency and space utilization are improved. Rate.
Patent Information
- Application Number
- CN202411559243.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-04
- Publication Date
- 2025-02-18
AI Technical Summary
In the prior art, the syringe is required to manually operate the syringe for filtering during sample processing, and the steps are cumbersome and difficult to automate, resulting in low space utilization and large manual labor.
A syringe operating device is designed, including a cylinder jaw assembly and a piston plug-in assembly. The separation of the syringe, sample pouring and liquid pressing are achieved through a robotic hand to automatically complete the filter pressing operation.
The syringe operation is automated, manual labor is reduced, and the problem of inadequate dissolving samples is difficult to press filters, which improves space utilization and leaves enough operating space for the robot.
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Figure CN119456068A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of sample processing equipment, and in particular to a syringe operating device and a sample processing equipment. Background Art
[0002] In the process of drug synthesis, a lot of repetitive work is required in the steps of sample dissolution, purification, and re-dissolution. After the powder sample is dissolved, the re-dissolved sample cannot be used directly for experimental detection because the detection device has high requirements for the particle size of the sample. Instead, it needs to be filtered by syringe. During this period, the sample needs to be mixed manually, heated, etc. to dissolve quickly. After the sample is poured into the syringe barrel, the filter element is installed at the liquid outlet of the syringe, and then the syringe piston rod is installed. Then, a lot of manual effort is required to squeeze the sample through the filter membrane into the receiving container. Sometimes, when encountering a sample that is not fully dissolved, it is difficult to squeeze the sample out completely manually.
[0003] The filter press process (generally refers to a process of separating liquids and solids by applying pressure) is an indispensable process in experimental or industrial processes. The steps required for the filter press process in the experimental process are very cumbersome. For example, the above-mentioned filter press using a syringe cannot be replaced by other automated methods to manually insert and separate the syringe barrel and the syringe piston rod, manually pour the sample, manually press the liquid of the sample in the syringe filter kit into a receiving container, and manually discard it. Pouring the sample into the syringe requires a large degree of freedom. At the same time, due to the volume of the manipulator, the entire device must leave enough operating space for the manipulator to separate the syringe barrel and the syringe piston rod and pour the sample into the syringe barrel, thereby occupying a large area of space above the syringe and resulting in low space utilization. Summary of the invention
[0004] In order to at least partially solve the problems existing in the prior art, according to one aspect of the present invention, a syringe operating device is provided, and the technical solution is as follows.
[0005] The syringe operating device comprises a barrel clamping jaw assembly and a piston plug-in assembly; the barrel clamping jaw assembly has a closed state for clamping the syringe barrel, and the barrel clamping jaw assembly is movable between a first position and a second position along a first direction; the piston plug-in assembly is arranged above the barrel clamping jaw assembly, and can be raised and lowered relative to the barrel clamping jaw assembly along a second direction to separate the syringe piston rod from the syringe barrel or insert the syringe piston rod into the syringe barrel, and the second direction is perpendicular to the first direction; wherein, when a sample is added into the syringe barrel, the barrel clamping jaw assembly is limited to the first position; when the piston plug-in assembly separates the syringe piston rod from the syringe barrel or inserts the syringe piston rod into the syringe barrel, the barrel clamping jaw assembly is limited to the second position.
[0006] The syringe operating device of the present invention is based on the arrangement of a piston plug-in assembly and a barrel clamping claw assembly. In the first position, the barrel clamping claw assembly clamps the syringe barrel to clamp the syringe. Thereafter, the barrel clamping claw assembly drives the syringe to move to the second position. In the second position, the piston plug-in assembly rises, and the piston plug-in assembly separates the syringe barrel from the syringe piston rod. Subsequently, the barrel clamping claw assembly drives the syringe barrel back to the first position. In the first position, the sample can be poured into the syringe barrel by a manipulator. Thereafter, the barrel clamping claw assembly can drive the syringe barrel containing the sample to move back to the second position. In the second position, a filter pressing operation is performed: the piston plug-in assembly inserts the syringe piston rod back into the syringe barrel and presses the liquid in the sample in the syringe covered with a filter element into a receiving container at the same time. After the filter pressing is completed, the discarded syringe can be discarded by a manipulator. In this way, it is convenient to cooperate with the manipulator to realize the automation of operations such as separating the syringe, pouring the sample, pressing the liquid in the sample in the syringe with the filter into the receiving container and discarding it, which greatly reduces manual labor and avoids the situation that the sample that is not fully dissolved is difficult to filter out. The operations of pouring and filtering are respectively located at the first position and the second position along the first direction, and the utilization of the space above the syringe (i.e., the space along the second direction) is converted into the utilization of the front space (i.e., the space along the first direction), which saves the upper space occupied by the entire syringe operating device and greatly improves the space utilization rate. The entire syringe operating device can leave enough operating space for the manipulator, satisfying the degree of freedom required for the manipulator to perform the pouring operation.
[0007] Exemplarily, the barrel clamp assembly includes a first clamp, a first driving member and a second driving member, the first driving member is connected to the first clamp via a first connecting member to drive the first clamp to switch between a closed state for clamping the syringe barrel and a loose state for loosening the syringe barrel, and the second driving member is connected to the first clamp via a second connecting member to drive the first clamp to move between a first position and a second position along a first direction.
[0008] Exemplarily, the first connecting member has a fixed connecting end and a sliding connecting end, the fixed connecting end is fixedly connected to the first clamping jaw, the sliding connecting end is connected to the end of the first driving member through a sliding connecting structure, and the sliding connecting end can slide between a third position and a fourth position along a third direction relative to the first driving member, the third direction is perpendicular to the first direction, and the barrel clamping jaw assembly is in a closed state when the sliding connecting end slides to the third position, and is in a loose state when the sliding connecting end slides to the fourth position.
[0009] Exemplarily, the second driving member has a main body and a telescopic body extending or retracting relative to the main body along a first direction, and the second connecting member is arranged on the telescopic body.
[0010] Exemplarily, the piston insertion and extraction assembly includes a third driving member, a pushing member and at least two clamping claws. The third driving member is connected to the at least two clamping claws through a third connecting member to drive the clamping claws to clamp the syringe piston rod or release the syringe piston rod. The pushing member is arranged between the at least two clamping claws.
[0011] Exemplarily, the piston plug-in assembly is connected to a lifting drive assembly, which includes a fourth drive member, a screw rod and a thrust plate. The fourth drive member drives the screw rod to drive the piston plug-in assembly and the thrust plate to lift and lower along the second direction.
[0012] Exemplarily, a pressure detection member is provided between the thrust plate and the end of the clamping claw, and the pressure detection member is used to detect the reaction force exerted on the piston rod of the syringe.
[0013] Exemplarily, the thrust plate has a plate body connected to the screw and a pushing body extending from the plate body toward a direction away from the screw, one end of the pressure detection member abuts against the pushing body, and the other end abuts against the end of the clamping claw through a connecting block.
[0014] Exemplarily, a piston rod clamp assembly is arranged between the barrel clamp assembly and the piston insertion assembly, and the piston rod clamp assembly has two second jaws, and the two second jaws have a positioning and guiding state enclosed around the syringe piston rod and an open state with a predetermined angle between each other. After the piston insertion assembly pulls out the syringe piston rod to a predetermined height relative to the syringe barrel, the two second jaws are in the positioning and guiding state; when the piston insertion assembly inserts the syringe piston rod into the syringe barrel to squeeze out the liquid, the two second jaws are in the open state.
[0015] Exemplarily, the two second jaws are respectively provided with a plurality of first teeth and a plurality of second teeth. When the two second jaws are in a positioning and guiding state, the first teeth and the second teeth are staggered and closed to form a positioning and guiding cavity between the two second jaws for the syringe piston rod to pass through.
[0016] Exemplarily, the syringe operating device further comprises a mounting plate, on one side of which a filter element support plate is arranged, and the filter element support plate is used to support the filter element connected to the bottom of the syringe barrel.
[0017] Exemplarily, before the syringe piston rod is separated from the syringe barrel, the syringe piston rod is pressed by the piston plug-in assembly until the bottom of the syringe barrel is consistent with the installation height of the filter element.
[0018] According to another aspect of the present invention, a sample processing device is provided. The sample processing device includes an operating table and the syringe operating device as described above. The syringe operating device is arranged on the operating table.
[0019] A series of simplified concepts are introduced in the summary of the invention, which will be further described in detail in the detailed description. The summary of the invention does not mean to attempt to define the key features and essential technical features of the claimed technical solution, nor does it mean to attempt to determine the scope of protection of the claimed technical solution.
[0020] The advantages and features of the present invention are described in detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] The following drawings of the present invention are used as part of the present invention for understanding the present invention. The drawings show the embodiments of the present invention and their descriptions, and are used to explain the principles of the present invention. In the drawings,
[0022] Figure 1 A perspective view of a syringe operating device according to an exemplary embodiment of the present invention;
[0023] Figure 2 for Figure 1 Enlarged view of part A in the middle;
[0024] Figure 3 for Figure 1 A perspective view of the syringe operating device shown from another angle;
[0025] Figure 4 for Figure 1 A perspective view of the barrel jaw assembly shown;
[0026] Figure 5 for Figure 1 A perspective view of the piston rod clamp assembly shown;
[0027] Figure 6 for Figure 5 The reference diagram of the piston rod clamp assembly in use is shown;
[0028] Figure 7 for Figure 1 A three-dimensional view of the syringe and filter element combined.
[0029] The above drawings include the following reference numerals:
[0030] 10. syringe operating device; 110. barrel clamping jaw assembly; 111. first clamping jaw; 1111. mounting portion; 1111a. second mounting hole; 112. first driving member; 113. second driving member; 1131. body; 1132. telescopic body; 114. first connecting member; 1141. fixed connecting end; 1141a. first mounting hole; 1142. sliding connecting end; 115. second connecting member; 1151. first connecting portion; 1152. second connecting portion; 116. sliding connection structure; 1161. V-shaped protrusion; 1162. groove; 1162a. V-shaped groove; 120. piston plug-in assembly; 121. third driving member; 122. pushing member; 1221. pushing portion; 1222. fixing portion; 123. clamping claw; 124. third connecting member; 130. Lifting drive assembly; 131, fourth drive member; 132, screw rod; 133, thrust pressure plate; 1331, plate body; 1332, pushing body; 140, pressure detection member; 150, connecting block; 160, fixing plate; 161, first fixing surface; 162, second fixing surface; 163, slide rail; 170, piston rod clamping assembly; 171, second clamping jaw; 1711, first tooth; 1712, second tooth; 172, positioning guide cavity; 173, fifth drive member; 180, mounting plate; 181, filter element support plate; 1811, support groove; 1811a, through hole; 190, linear guide assembly; 20, syringe; 210, syringe barrel; 211, bottom; 220, syringe piston rod; 30, filter element; X, first direction; Y, second direction; Z, third direction. DETAILED DESCRIPTION
[0031] In the following description, a large amount of details are provided so that the present invention can be thoroughly understood. However, it will be appreciated by those skilled in the art that the following description only exemplarily illustrates a preferred embodiment of the present invention, and the present invention can be implemented without one or more such details. In addition, in order to avoid confusion with the present invention, some technical features well known in the art are not described in detail.
[0032] In order to fully understand the embodiments of the present invention, detailed structures will be presented in the following description. Obviously, the implementation of the embodiments of the present invention is not limited to the specific details familiar to those skilled in the art. The preferred embodiments of the present invention are described in detail below, but in addition to these detailed descriptions, the present invention may also have other embodiments.
[0033] An embodiment of the present invention provides a syringe operating device. The syringe operating device of the present invention can be applied to a sample processing device. The syringe operating device according to an embodiment of the present invention will be described in detail below in conjunction with the accompanying drawings.
[0034] Combined with reference Figure 1 and Figure 7 , the syringe operating device 10 may include a barrel clamping jaw assembly 110 and a piston plug-in assembly 120. The barrel clamping jaw assembly 110 may be used to clamp the syringe barrel 210, and the barrel clamping jaw assembly 110 may be movable between a first position and a second position along a first direction X. The piston plug-in assembly 120 may be arranged above the barrel clamping jaw assembly 110, and may be raised and lowered relative to the barrel clamping jaw assembly 110 along a second direction Y to separate the syringe piston rod 220 from the syringe barrel 210 or insert the syringe piston rod 220 into the syringe barrel 210. The second direction Y may be perpendicular to the first direction X. When adding a sample into the syringe barrel 210, the barrel clamping jaw assembly 110 may be limited to the first position, and the sample mentioned here may be a solid-liquid mixture or a liquid. When the piston plug-in assembly 120 separates the syringe piston rod 220 from the syringe barrel 210 or inserts the syringe piston rod 220 into the syringe barrel 210, the barrel clamping jaw assembly 110 may be limited to the second position.
[0035] The syringe operating device 10 of the present invention is based on the settings of the piston plug-in assembly 120 and the barrel clamping jaw assembly 110. In the first position, the barrel clamping jaw assembly 110 clamps the syringe barrel 210 to clamp the syringe 20. Then, the barrel clamping jaw assembly 110 drives the syringe 20 to move to the second position. In the second position, the piston plug-in assembly 120 rises, and the piston plug-in assembly 120 separates the syringe barrel 210 from the syringe piston rod 220. Then, the barrel clamping jaw assembly 110 drives the syringe barrel 210 back to the first position. In the first position, the sample can be poured into the syringe barrel 210 by a manipulator; thereafter, the barrel clamping jaw assembly 110 can drive the syringe barrel 210 containing the sample to move back to the second position. In the second position, the filter pressing operation is performed: the piston plug-in assembly 120 inserts the syringe piston rod 220 back into the syringe barrel 210 and presses the liquid in the sample in the syringe 20 with the filter element 30 into the receiving container. After the filter pressing is completed, the discarded syringe 20 can be discarded by the manipulator. In this way, it is convenient to cooperate with the manipulator to realize the automation of operations such as separating the syringe 20, pouring the sample, pressing the liquid in the sample in the syringe 20 with the filter element 30 into the receiving container and discarding, which greatly reduces manual labor and avoids the situation that the sample that is not fully dissolved is difficult to filter out. The operations of pouring and filtering are respectively located at the first position and the second position along the first direction X, which converts the utilization of the space above the syringe 20 (that is, the space along the second direction Y) into the utilization of the front space (that is, the space along the first direction X), saving the upper space occupied by the entire syringe operating device 10 and greatly improving the space utilization rate. The entire syringe operating device 10 leaves enough operating space for the manipulator, satisfying the degree of freedom required for the manipulator to perform the pouring operation.
[0036] Combined with reference Figure 1 , Figure 4 and Figure 7 , the barrel clamping jaw assembly 110 may include the first jaw 111, the first driver 112 and the second driver 113. The first driver 112 can be connected with the first jaw 111 through the first connecting member 114 to drive the first jaw 111 to switch between the closed state of clamping the syringe barrel 210 and the released state of releasing the syringe barrel 210. The second driver 113 can be connected with the first jaw 111 through the second connecting member 115 to drive the first jaw 111 to move between the first position and the second position along the first direction X. Like this, the barrel clamping jaw assembly 110 realizes to move between the first position and the second position along the first direction X by the second driver 113, and the operation of pouring sample and filter pressing is performed respectively at these two positions, compared with the device of pouring sample and filter pressing operation at the same position, the syringe operating device 10 of the present invention will convert the utilization space above the syringe 20 into the space utilization in front, saves the upper space occupied by the whole syringe operating device 10, and greatly improves the space utilization rate. Among them, the number of the first clamping jaws 111 can be two, and the end surfaces of the two first clamping jaws 111 for clamping the syringe 20 can be recessed with arc segments or polygonal segments similar to the shape of the outer wall of the syringe barrel 210 in directions away from each other, so as to facilitate clamping the syringe barrel 210. For example, in an exemplary embodiment of the present invention, the syringe barrel 210 is cylindrical, and the end surfaces of the two first clamping jaws 111 for clamping the syringe 20 are recessed with arc segments in directions away from each other.
[0037] Further, in order to improve the stability of the first clamping jaw 111 moving along the first direction X, and to enhance the compactness of the first clamping jaw 111, the first driving member 112 and the second driving member 113 to save the occupied space, the first clamping jaw 111 and the first driving member 112 are connected through the first connecting member 114, and then the two are fixed to the second driving member 113 through the second connecting member 115. The second connecting member 115 may have a first connecting portion 1151 connected to the first driving member 112 and a second connecting portion 1152 connected to the second driving member 113, the first connecting portion 1151 may be connected to the first driving member 112 through fasteners such as screws or bolts, and the second connecting portion 1152 may be connected to the second driving member 113 through fasteners such as screws or bolts, and of course other connection methods are not excluded, such as welding or bonding, etc.
[0038] Combined with reference Figure 1 and Figure 4, the first connecting member 114 can have a fixed connection end 1141 and a sliding connection end 1142. The fixed connection end 1141 can be fixedly connected to the first clamping jaw 111. The sliding connection end 1142 can be connected to the end of the first driving member 112 through a sliding connection structure 116, and the sliding connection end 1142 can slide between the third position and the fourth position relative to the first driving member 112 along the third direction Z. The third direction Z can be perpendicular to the first direction X. The barrel clamping jaw assembly 110 can be in a closed state when the sliding connection end 1142 slides to the third position. It can be in a released state when the sliding connection end 1142 slides to the fourth position. Through the fixed connection end 1141 and the sliding connection end 1142 of the first connecting member 114, the first driving member 112 drives the first clamping jaw 111 to switch between a closed state and a loosened state to clamp or loosen the syringe 20. The first clamping jaw 111, the first connecting member 114 and the first driving member 112 can be installed or disassembled, thereby facilitating replacement or maintenance.
[0039] Specifically, the sliding connection structure 116 may include two V-shaped protrusions 1161 formed by protruding from both sides of the sliding connection end 1142 in the second direction Y and a groove 1162 formed by being recessed in the end surface of the first driving member 112 close to the first clamping jaw 111 in the direction away from the first clamping jaw 111. Two V-shaped grooves 1162a may be recessed on both sides of the groove 1162 in the second direction Y, and the V-shaped protrusions 1161 are limited in the V-shaped grooves 1162a to slide to slide and connect the first driving member 112 and the first connecting member 114. A first mounting hole 1141a may be provided on the fixed connection end 1141, and a mounting portion 1111 may be extended from the first clamping jaw 111 in the direction close to the first driving member 112, and a second mounting hole 1111a may be provided on the mounting portion 1111, and fasteners such as screws or bolts are sequentially passed through the first mounting hole 1141a and the second mounting hole 1111a to connect the first clamping jaw 111 and the first connecting member 114. In this way, the first connecting member 114 can enhance the firmness of the connection between the first clamping jaw 111 and the first driving member 112, and facilitate disassembly and assembly. It should be noted that the number of the first mounting holes 1141a can be at least one, and the number of the second mounting holes 1111a can be at least one, and the number of the first mounting holes 1141a and the second mounting holes 1111a correspond to each other. Of course, it is not excluded that the protrusion formed on the end surface of the first driving member 112 close to the first clamping jaw 111, the two V-shaped protrusions 1161 formed by the protrusion protruding on both sides of the second direction Y, the groove 1162 concavely formed on the sliding connection end 1142 in the direction away from the first driving member 112, and the two sides of the groove 1162 facing the second direction Y can be concave with two V-shaped grooves 1162a, and the V-shaped protrusion 1161 is limited to slide in the V-shaped groove 1162a to slide and connect the first driving member 112 and the first connecting member 114. In addition, in an embodiment not shown in the present invention, the combination of the V-shaped groove 1162a and the V-shaped protrusion 1161 can also be a combination of a square groove and a square protrusion or a combination of a polygonal groove and a polygonal protrusion, etc. The sliding connection end 1142 and the first driving member 112 include but are not limited to the above-mentioned connection methods, for example, they can also be connected by a slide rail connection and other connection methods. The fixed connection end 1141 and the first clamping jaw 111 include but are not limited to the above-mentioned connection methods, for example, they can also be connected by welding or bonding and other connection methods.
[0040] Again, refer to Figure 1 and Figure 4, the second driving member 113 may include a body 1131 and a telescopic body 1132 extending or retracting relative to the body 1131 along the first direction X. The second connecting member 115 may be arranged on the telescopic body 1132. In this way, the second driving member 113 may drive the first clamping jaw 111 to move between the first position and the second position through the telescopic body 1132 extending or retracting relative to the body 1131 along the first direction X, and perform the dumping operation or the filter pressing operation at the two positions along the first direction X, thereby saving the space of the syringe operating device 10 in the second direction Y, leaving enough operating space for the manipulator, satisfying the degree of freedom required for the manipulator to perform the dumping operation, and greatly improving the space utilization. For example, the second driving member 113 may be a slide cylinder, the body 1131 may be a cylinder, the telescopic body 1132 may be a push rod and a slide, and the cylinder uses air pressure as a power source to make the piston push the push rod to drive the slide to do linear motion, thereby realizing that the barrel clamping jaw assembly 110 does linear motion along the first direction X.
[0041] Combined with reference Figure 1 , Figure 2 , Figure 4 and Figure 7 The piston plug-in assembly 120 may include a third driving member 121, a pushing member 122, and at least two clamping claws 123. The third driving member 121 may be connected to the at least two clamping claws 123 through a third connecting member 124 to drive the clamping claws 123 to clamp the syringe piston rod 220 or release the syringe piston rod 220. The pushing member 122 may be disposed between the at least two clamping claws 123. The piston plug-in assembly 120 may clamp the syringe piston rod 220 through the two clamping claws 123, and abut the end surface of the end of the syringe piston rod 220 through the pushing member 122. When the piston plug-in assembly 120 performs the action of pulling the syringe piston rod 220 out of the syringe barrel 210, the two clamping claws 123 clamp the syringe piston rod 220 to drive it to rise. When the piston plug-in assembly 120 performs the action of inserting the syringe piston rod 220 into the syringe barrel 210, the pushing piece 122 pushes the end surface of the end of the syringe piston rod 220 to drive it to descend. Both actions can be achieved only through the piston plug-in assembly 120, saving costs.
[0042] Furthermore, the end surfaces of the two clamping claws 123 for clamping the syringe piston rod 220 can be recessed with arc segments or polygonal segments similar in shape to the outer wall of the syringe piston rod 220 in a direction away from each other, so as to facilitate clamping the syringe piston rod 220. The pushing member 122 can have a pushing portion 1221 for pushing the end of the syringe piston rod 220 and a fixing portion 1222 extending from the pushing portion 1221 toward the third driving member 121. The fixing portion 1222 and the third driving member 121 can be fixed by fasteners such as screws or bolts, so that the pushing member 122 is detachable relative to the third driving member 121, so that the piston plug-in assembly 120 can be applied to different application scenarios, saving costs. The connection method between the third connecting member 124 and the third driving member 121 and the two clamping claws 123 can be the same as the connection method between the first connecting member 114 and the first clamping claw 111 and the first driving member 112, that is, the third connecting member 124 is fixedly connected to the two clamping claws 123 and is slidably connected to the third driving member 121, and the details are not repeated here.
[0043] Combined with reference Figure 1 , Figure 2 , Figure 3 and Figure 7 , the piston plug-in assembly 120 may be connected to a lifting drive assembly 130. The lifting drive assembly 130 may include a fourth drive member 131, a screw rod 132, and a thrust plate 133. The fourth drive member 131 may drive the screw rod 132 to drive the piston plug-in assembly 120 and the thrust plate 133 to lift and lower along the second direction Y. The thrust plate 133 may be connected to the screw rod 132, and when the screw rod 132 extends or retracts relative to the fourth drive member 131 along the second direction Y, it may drive the thrust plate 133 to lift and lower along the second direction Y. The thrust plate 133 may be connected to the piston plug-in assembly 120, and in the process that the screw rod 132 drives the thrust plate 133 to lift and lower along the second direction Y, the thrust plate 133 also drives the piston plug-in assembly 120 to lift and lower along the second direction Y, thereby realizing the automatic plugging and unplugging of the syringe piston rod 220 and saving manual labor.
[0044] Again, refer to Figure 1 , Figure 2 , Figure 3 and Figure 7A pressure detection member 140 may be provided between the thrust plate 133 and the end of the clamping claw 123. The pressure detection member 140 may be used to detect the reaction force exerted on the syringe piston rod 220. By providing the pressure detection member 140, when the syringe piston rod 220 is inserted into the syringe barrel 210 (referred to as the insertion process for convenience of description), accurate feedback is provided for the pressure generated by the thrust plate 133, thereby ensuring the smoothness during the insertion process and preventing the syringe barrel 210 from being crushed due to excessive pressure. Specifically, the pressure detection member 140 may be a pressure sensor. When the syringe piston rod 220 receives the reaction force, after the reaction force is transmitted to the pressure detection member 140, the pressure detection member 140 may display the pressure exerted by the thrust plate 133, and the power output by the fourth driving member 131 may be controlled by pressure feedback, thereby achieving the purpose of pressure controllability and ensuring that the force output during the insertion process is smooth (i.e., slow and controllable).
[0045] Combined with reference Figures 1 to 3 The thrust plate 133 may include a plate body 1331 connected to the screw rod 132 and a pushing body 1332 extending from the plate body 1331 in a direction away from the screw rod 132. One end of the pressure detection member 140 may abut against the pushing body 1332, and the other end may abut against the end of the clamping claw 123 through the connecting block 150. The arrangement of the pushing body 1332 facilitates the connection between the pressure detection member 140 and the thrust plate 133, and the arrangement of the connecting block 150 facilitates the connection between the pressure detection member 140 and the end of the clamping claw 123, thereby enhancing the firmness of the connection between the pressure detection member 140 and the thrust plate 133 and the end of the clamping claw 123.
[0046] Furthermore, the syringe operating device 10 also includes a fixed plate 160 arranged along the second direction Y, and the piston plug-in assembly 120 and the lifting drive assembly 130 are arranged on the fixed plate 160. Specifically, the fixed plate 160 has a first fixed surface 161 and a second fixed surface 162 along the first direction X, and a slide rail 163 can be arranged on the fixed plate 160, and the fourth driving member 131 and the screw rod 132 can be installed on the first fixed surface 161, the plate body 1331 of the thrust plate 133 can be connected to the screw rod 132 and slide relative to the slide rail 163, and the piston plug-in assembly 120 can be installed on the second fixed surface 162 through the thrust body 1332. In this way, the piston plug-in assembly 120 and the lifting drive assembly 130 are arranged along the first direction X, which saves the space of the syringe operating device 10 along the second direction Y, thereby greatly improving the space utilization.
[0047] Combined with reference Figure 1 , Figure 5 , Figure 6 and Figure 7A piston rod clamp assembly 170 may be provided between the barrel clamp assembly 110 and the piston plug assembly 120. The piston rod clamp assembly 170 may have two second clamps 171. The two second clamps 171 may have a positioning guide state enclosed around the syringe piston rod 220 and an open state with a predetermined angle between them. After the piston plug assembly 120 pulls the syringe piston rod 220 out of the syringe barrel 210 to a predetermined height, the two second clamps 171 may be in a positioning guide state (such as Figure 6 As shown, at this time, the two second clamping jaws 171 are in a positioning and guiding state. When the piston plug-in assembly 120 inserts the syringe piston rod 220 into the syringe barrel 210 to squeeze out the liquid, the two second clamping jaws 171 can be in an open state (as shown in FIG. Figure 5 As shown, at this time, the two second clamping jaws 171 are in an open state). When the two second clamping jaws 171 of the piston rod clamping jaw assembly 170 are enclosed around the syringe piston rod 220, the syringe piston rod 220 is positioned and guided, thereby preventing the syringe piston rod 220 from tilting and ensuring that the syringe piston rod 220 can be accurately inserted into the syringe barrel 210, thereby achieving accurate automated operation.
[0048] Exemplarily, a plurality of first teeth 1711 and a plurality of second teeth 1712 may be respectively provided on the two second jaws 171. When the two second jaws 171 are in the positioning and guiding state, the first teeth 1711 and the second teeth 1712 are staggered and closed, so that the two second jaws 171 can form a positioning and guiding cavity 172 for the syringe piston rod 220 to pass through. Usually, the syringe piston rod 220 is a cross structure, and the cavity wall of the positioning and guiding cavity 172 formed by the two second jaws 171 staggered and closed by the first teeth 1711 and the second teeth 1712 has a smooth effect, thereby having a good positioning and guiding effect on the syringe piston rod 220 of the cross structure, ensuring that the syringe piston rod 220 can be accurately inserted into the syringe barrel 210.
[0049] Specifically, the piston rod clamp assembly 170 can also include a fifth driving member 173, which drives the two second clamps 171 to rotate between a fifth position in an open state and a sixth position in a positioning guide state, thereby preventing the two second clamps 171 from blocking the piston insertion assembly 120 from performing a filter press operation.
[0050] Again, refer to Figure 1 and Figure 7, the syringe operating device 10 can also include a mounting plate 180. The barrel clamping jaw assembly 110 can be arranged on the mounting plate 180. A filter element support plate 181 can be provided on one side of the mounting plate 180 (i.e., a side away from the barrel clamping jaw assembly 110). The filter element support plate 181 can be used to support the filter element 30 connected to the bottom 211 of the syringe barrel 210. The bottom of the syringe barrel 210 clamped by the barrel clamping jaw assembly 110 is connected with the filter element 30. By arranging the filter element support plate 181 to support the filter element 30, it is avoided that the syringe 20 and the filter element 30 shake during the filter pressing process, and the filter pressing effect is poor. Specifically, the filter element support plate 181 has a support groove 1811 that opens away from the barrel clamping jaw assembly 110, and the bottom of the support groove 1811 is provided with a through hole 1811a, which facilitates the filter element 30 to be placed in the support groove 1811. A notch may be provided on the side of the support groove 1811 away from the mounting plate 180, and a notch may also be provided on the side of the through hole 1811a away from the mounting plate 180, so that when the barrel clamp assembly 110 clamps the syringe 20 connected with the filter element 30 and moves from the first position to the second position, it is convenient to place the filter element 30 in the support groove 1811.
[0051] Again, refer to Figure 1 and Figure 7 Before separating the syringe piston rod 220 from the syringe barrel 210, the syringe piston rod 220 is pressed by the piston plug-in assembly 120 until the bottom 211 of the syringe barrel 210 is consistent with the installation height of the filter element 30, that is, the bottom 211 of the syringe barrel 210 and the filter element 30 are installed in place. At this time, the syringe piston rod 220 is fully inserted into the syringe barrel 210, that is, when the above-mentioned syringe piston rod 220 is subjected to a reaction force. In this way, it is ensured that there is no leakage at the connection between the syringe 20 and the filter element 30 during the filter pressing process, and the height of the syringe piston rod 220 is consistent each time it is pulled out.
[0052] The syringe operating device 10 may further include a linear guide assembly 190. The barrel clamp assembly 110, the piston plug assembly 120, the lifting drive assembly 130, the piston rod clamp assembly 170, etc. mentioned above can perform linear motion along the third direction Z on the linear guide assembly 190 through the mounting plate 180. In this way, the filter press process can be performed at different positions in the third direction Z through the linear guide assembly 190.
[0053] According to another aspect of the present invention, a sample processing device is provided, which may include an operating table and the syringe operating device 10 as described above. The syringe operating device 10 may be arranged on the operating table. Since the syringe operating device 10 as described above has the above-mentioned beneficial effects, the sample processing device including the syringe operating device 10 as described above also has the above-mentioned beneficial effects, which will not be described one by one here.
[0054] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by directional words such as "front", "back", "up", "down", "left", "right", "lateral", "vertical", "vertical", "horizontal", "top", "bottom", etc. is usually based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present invention; the directional words "inside" and "outside" refer to the inside and outside relative to the contour of each component itself.
[0055] For ease of description, regional relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the regional positional relationship between one or more components or features shown in the figure and other components or features. It should be understood that regional relative terms include not only the orientation of the components as described in the figure, but also different orientations in use or operation. For example, if the components in the accompanying drawings are inverted as a whole, the components "above other components or features" or "above other components or features" will include the situation where the components are "below other components or structures" or "below other components or structures". Therefore, the exemplary term "above" may include both "above" and "below". In addition, these components or features may also be positioned at other different angles (e.g., rotated 90 degrees or other angles), and this article is intended to include all of these situations.
[0056] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, parts, components and / or combinations thereof.
[0057] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein.
[0058] The present invention has been described by the above embodiments, but it should be understood that the above embodiments are only for the purpose of example and description, and are not intended to limit the present invention to the scope of the described embodiments. In addition, it can be understood by those skilled in the art that the present invention is not limited to the above embodiments, and more variations and modifications can be made according to the teachings of the present invention, and these variations and modifications all fall within the scope of the protection claimed by the present invention. The protection scope of the present invention is defined by the attached claims and their equivalents.
Claims
1. A syringe operating device, characterized in that: It includes a barrel clamping jaw assembly and a piston plug-in assembly; The barrel clamping jaw assembly is used to clamp the syringe barrel, and the barrel clamping jaw assembly is movable between a first position and a second position along a first direction; The piston insertion assembly is arranged above the barrel clamping jaw assembly, and can be raised and lowered relative to the barrel clamping jaw assembly along a second direction to separate the syringe piston rod from the syringe barrel or insert the syringe piston rod into the syringe barrel, and the second direction is perpendicular to the first direction; When a sample is added into the syringe barrel, the barrel clamp assembly is limited to the first position; when the piston insertion and extraction assembly separates the syringe piston rod from the syringe barrel or inserts the syringe piston rod into the syringe barrel, the barrel clamp assembly is limited to the second position.
2. The syringe operating device according to claim 1, characterized in that: The barrel clamping jaw assembly includes a first clamping jaw, a first driving member and a second driving member. The first driving member is connected to the first clamping jaw through a first connecting member to drive the first clamping jaw to switch between a closed state of clamping the syringe barrel and a loose state of loosening the syringe barrel. The second driving member is connected to the first clamping jaw through a second connecting member to drive the first clamping jaw to move between the first position and the second position along the first direction.
3. The syringe operating device according to claim 2, characterized in that: The first connecting member has a fixed connecting end and a sliding connecting end, the fixed connecting end is fixedly connected to the first clamping jaw, the sliding connecting end is connected to the end of the first driving member through a sliding connecting structure, and the sliding connecting end is slidable between a third position and a fourth position along a third direction relative to the first driving member, and the third direction is perpendicular to the first direction. The barrel clamping jaw assembly is in the closed state when the sliding connecting end slides to the third position, and is in the released state when the sliding connecting end slides to the fourth position.
4. The syringe operating device according to claim 2, characterized in that: The second driving member comprises a main body and a telescopic body extending or retracting relative to the main body along the first direction, and the second connecting member is arranged on the telescopic body.
5. The syringe operating device according to claim 1, characterized in that: The piston insertion and extraction assembly includes a third driving member, a pushing member and at least two clamping claws. The third driving member is connected to at least two of the clamping claws through a third connecting member to drive the clamping claws to clamp the syringe piston rod or release the syringe piston rod. The pushing member is arranged between at least two of the clamping claws.
6. The syringe operating device according to claim 5, characterized in that: The piston plug-in assembly is connected to a lifting drive assembly, which includes a fourth drive member, a screw rod and a thrust plate. The fourth drive member drives the screw rod to drive the piston plug-in assembly and the thrust plate to lift and lower along the second direction.
7. The syringe operating device according to claim 6, characterized in that: A pressure detection component is provided between the thrust plate and the end of the clamping claw, and the pressure detection component is used to detect the reaction force exerted on the syringe piston rod.
8. The syringe operating device according to claim 7, characterized in that: The thrust plate has a plate body connected to the screw and a pushing body extending from the plate body toward a direction away from the screw. One end of the pressure detection member abuts against the pushing body, and the other end abuts against the end of the clamping claw through a connecting block.
9. The syringe operating device according to claim 1, characterized in that: A piston rod clamp assembly is arranged between the barrel clamp assembly and the piston plug-in assembly, and the piston rod clamp assembly has two second clamps, and the two second clamps have a positioning and guiding state enclosed around the syringe piston rod and an open state with a predetermined angle between them. After the piston plug-in assembly pulls out the syringe piston rod to a predetermined height relative to the syringe barrel, the two second clamps are in the positioning and guiding state; when the piston plug-in assembly inserts the syringe piston rod into the syringe barrel to squeeze out the liquid, the two second clamps are in the open state.
10. The syringe operating device according to claim 9, characterized in that: The two second clamping jaws are respectively provided with a plurality of first teeth and a plurality of second teeth. When the two second clamping jaws are in the positioning and guiding state, the first teeth and the second teeth are staggered and closed to form a positioning and guiding cavity for the syringe piston rod to pass through between the two second clamping jaws.
11. The syringe operating device according to claim 1, characterized in that: The syringe operating device also includes a mounting plate, and a filter element support plate is arranged on one side of the mounting plate. The filter element support plate is used to support the filter element connected to the bottom of the syringe barrel.
12. The syringe operating device according to claim 11, characterized in that Before separating the syringe piston rod from the syringe barrel, the syringe piston rod is pressed by the piston plug-in assembly until the bottom of the syringe barrel is consistent with the installation height of the filter element.
13. A sample processing device, characterized in that: It comprises an operating table and a syringe operating device as described in any one of claims 1 to 12, wherein the syringe operating device is arranged on the operating table.