Modified milk powder for old people for assisting in reducing blood sugar level and preparation method of modified milk powder

Abstract

The invention discloses modified milk powder for old people for assisting in reducing blood sugar level and a preparation method of the modified milk powder. The modified milk powder comprises a milk-based composition, a hypoglycemic functional composition, a dietary fiber composition, a vitamin composition and a mineral composition. The composition with the hypoglycemic function is prepared from mulberry leaf extract, barley malt flour, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder and lactobacillus rhamnosus JYLR-005 and has the functions of regulating carbohydrate metabolism and improving pancreas islet beta-cells, animal experiment research proves that the composition can remarkably reduce fasting blood glucose of hyperglycemia model rats, and the blood glucose reducing effect is good. The modified milk powder provided by the invention has the advantages that the effect of assisting in reducing blood sugar can be realized by drinking the modified milk powder after half of medication, the reduction rate of fasting blood sugar value is 4.73-10.77%, and the reduction rate of blood sugar value after 1 hour after meal is 5.89-14.60%. The modified milk powder provided by the invention has the advantages that the effect of assisting in reducing blood sugar can be realized by taking the modified milk powder after half of medication. Compared with the total mixing time of the modified milk powder prepared by three-dimensional equipment, the total mixing time of the modified milk powder prepared by adopting a pneumatic mixing process is obviously shortened, the working efficiency is very effectively improved, and meanwhile, the personnel consumption is reduced. On the basis of meeting the nutritional requirements of consumers on dairy product intake, the modified milk powder has lower blood sugar load, is wider in intake crowd compared with conventional modified milk powder, and is more beneficial to old people suffering from obesity, hyperglycemia and the like; meanwhile, the preparation method is simple and efficient, and has a wide application prospect.

Description

Technical Field

[0001] The invention relates to a modulated milk powder for elderly people that assists in lowering blood sugar levels and a preparation method thereof, belonging to the technical field of modulated milk powder preparation. Background Art

[0002] Diabetes has become one of the serious public health problems in the world. Diabetes has become one of the potential threats to the health of adults in my country. Especially with the increase of age and the aging of body functions, the probability of elderly people suffering from diabetes increases significantly. Elderly people with high blood sugar levels or who have been diagnosed with diabetes need to intervene as soon as possible to better control blood sugar levels and delay the progression of diabetes. Due to its complications and high damage to the body, and its incurability, we need to pay more attention to it.

[0003] Currently, the prevention and treatment of abnormal blood sugar levels in the elderly are more often done by controlling diet, taking medication, injecting insulin, etc. Among them, due to controlling diet and a small number of food types, it will lead to nutritional deficiencies in the elderly over a long period of time. Therefore, it is particularly important to develop a food that is nutritious and can help lower blood sugar.

[0004] Therefore, in-depth research on the nutritional needs and blood sugar production mechanism of the elderly shows that formula milk powder is the most suitable food. Formulated milk powder can be added with a variety of nutrients that meet the nutritional needs of the elderly, such as protein, calcium, iron, vitamin C, etc., and can also be mixed with functional substances that help lower blood sugar, such as regulating insulin secretion and sugar metabolism. In short, facing many consumers and even people with high blood sugar, developing a nutritious, functional, and low-priced formula milk powder that helps lower blood sugar is more beneficial to the public's needs. Summary of the invention

[0005] The purpose of the present invention is to provide a formula and preparation method of a modified milk powder for the elderly that assists in lowering blood sugar levels, so as to solve the problem of high blood sugar or malnutrition caused by diet control in elderly people with diabetes, and at the same time, it can assist in lowering blood sugar levels. The technical solution of the present invention is as follows

[0006] 1. A formula milk powder for assisting in lowering blood sugar levels for the elderly, comprising the following components and weights: 1-25 parts of a milk-based composition (skim milk powder, desalted whey powder and concentrated whey protein), 0.01-6 parts of a blood sugar-lowering functional composition (mulberry leaf extract, barley malt powder, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder, oligomaltosaccharide and Lactobacillus rhamnosus JYLR-005), 0.1-1 parts of a dietary fiber composition (oat bran), 0.01-0.075 parts of a vitamin composition (taurine, retinyl acetate, sodium L-ascorbate, cholecalciferol, dl-α-tocopherol acetate, folic acid), and 0.14-0.28 parts of a mineral composition (ferric pyrophosphate, zinc citrate, sodium selenite, calcium carbonate), and xylitol as a supplement.

[0007] 2 A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels, characterized in that it comprises the following steps: Step 1: Remove the outer packaging of the milk-based composition, the hypoglycemic functional composition, the vitamin composition, and the mineral composition, sterilize them in a large bag tunnel sterilizer and a transfer window, and set them aside; Step 2: After the raw material with the largest proportion in the formula is sieved through an oscillating sieve, it is sucked into the weighing tank by a vacuum feeder according to half of its proportion in the formula as the bottom layer of the tank; Step 3: Weigh the raw and auxiliary materials at the end of the ingredient list until the total weight is one tenth of the total weight of the formula, pass through a 30-50 mesh sieve, and then be sucked to 0.38m by a vacuum feeder 3 In the pneumatic mixing tank, the mixture is mixed under the mediation of nitrogen to obtain mixed powder I. The mixed powder I is transported to the weighing tank by nitrogen positive pressure, and the backflush is turned on to move 0.38m 3 The remaining material in the pneumatic mixing tank is blown into the weighing tank as the middle layer of the tank; Step 4: The remaining raw and auxiliary materials except those in steps 2 and 3 are sieved through an oscillating sieve and sucked into a weighing tank by a vacuum feeder according to the formula amount as the top layer of the mixture; Step 5: Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 Mixing is performed in a pneumatic mixing tank to obtain a total mixed powder; Step 6: The obtained total mixed powder is subjected to metal detection and then packaged by a fully automatic packaging machine to obtain a modified milk powder for the elderly that assists in lowering blood sugar; The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the quality rate is ≥99%.

[0008] 3. A formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 1, characterized in that the blood sugar lowering functional composition is one or more of 0.25-1 part of mulberry leaf extract, 0.17-0.75 part of barley malt powder, 0.17-0.75 part of white kidney bean powder, 0.01-0.05 part of L-arabinose, 0.02-0.05 part of lotus leaf powder, 0.02-0.1 part of ginkgo powder, 1-2 parts of isomaltooligosaccharide and 0.01-1 part of Lactobacillus rhamnosus JYLR-005, mixed in any proportion as mentioned above.

[0009] 4. A formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 1, characterized in that the milk-based composition is one or more of 9-10 parts of skim milk powder, 7-9 parts of desalted whey powder and 1-3 parts of concentrated whey protein, mixed in any proportion as mentioned above.

[0010] 5. A formula milk powder for assisting in lowering blood sugar level for the elderly as claimed in claim 1, characterized in that the protein content is not less than 20g / 100g, the calcium content is not less than 1000mg / 100g, and the amount of Lactobacillus rhamnosus JYLR-005 added is not less than 10 8 CFU / g.

[0011] 6. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 2, characterized in that the mixing conditions in steps 2 to 5 are: gas pressure 0.4-0.6MPa, flow rate 300-1000L / h, temperature 20-25°C.

[0012] 7 A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 2, characterized in that the premixing time in step 3 is 3-5 minutes, and the total mixing time in the step is 5-15 minutes.

[0013] 8. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as described in claim 2, characterized in that, in step 6, the metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, and non-iron φ≥1mm; the quantitative packaging and heat sealing treatment are carried out by a fully automatic packaging machine under the mediation of gas with a flow rate of 500-1000L / h and a pressure of 0.6-1.0MPa, the filling amount is controlled to be 25±0.2g / bag, and the quantitative packaging accuracy is above 99.9% to obtain the final product.

[0014] The present invention has the following beneficial effects:

[0015] The present invention is to prepare a milk-based composition, a hypoglycemic functional composition, a dietary fiber composition, a vitamin composition and a mineral composition in a certain proportion, and mix them evenly through a pneumatic process to obtain a modified milk powder for the elderly that assists in lowering blood sugar levels. The modified milk powder has the following advantages: The modulated milk powder provided by the present invention is rich in nutrition and suitable for consumption by elderly people with abnormal blood sugar levels. Studies have shown that excessive fat intake can lead to insulin resistance. The fat content in the modulated milk powder provided by the present invention is less than 14g / 100g. Compared with similar products, the fat content is low, which can reduce the dietary burden of the elderly and better control blood sugar. The modulated milk powder provided by the present invention is rich in protein (content not less than 20g / 100g) and calcium (content not less than 1000mg / 100g), and nutrients such as vitamin A, vitamin D, vitamin E, vitamin C, folic acid, magnesium, iron, selenium, taurine and dietary fiber are added to prevent anemia, increase appetite, maintain vitality and maintain gastrointestinal comfort. The combination of the above nutrients is in line with the recommendations of the Chinese Dietary Guidelines for the Elderly.

[0016] The modulated milk powder of the present invention is added with a variety of medicinal and edible substances that can assist in lowering blood sugar, and contains a variety of physiologically active factors. The mulberry leaf extract contains 1-deoxynojirimycin (DNJ), which reduces the digestion and absorption of sugar by the human body by inhibiting the activity of α-glucosidase; the barley malt powder activates the activity of adenylate-activated protein kinase (AMPK), thereby inhibiting excessive insulin secretion and promoting muscle cells to consume blood sugar; the bean protein contained in the white kidney bean extract is an α-amylase inhibitor, which can inhibit the digestion and absorption of carbohydrates in the body; L-arabinose can reduce the absorption of sucrose by inhibiting sucrase, thereby reducing the increase in blood sugar caused by the intake of sucrose; lotus leaf powder and ginkgo powder can improve the level of insulin secretion by the pancreas by improving the function of pancreatic β cells; the auxiliary blood sugar lowering mechanism of the above substances has been confirmed, the present invention has a synergistic effect by matching in a scientific proportion, solves the problem of poor functionality of the existing modulated milk powder, and long-term consumption can also help the elderly with abnormal blood sugar levels to lower blood sugar.

[0017] Animal experiments have shown that the present invention can significantly reduce the fasting blood sugar of hyperglycemic model rats, with a reduction rate of 30.26% to 73.53%. Human trial results show that drinking the modulated milk powder provided by the present invention after the dosage is halved has an auxiliary effect of lowering blood sugar, with a fasting blood sugar value reduction rate of 4.73% to 10.77%, and a blood sugar value reduction rate of 1 hour after a meal of 5.89% to 14.60%.

[0018] The modulated milk powder provided by the present invention adopts a pneumatic process for mixing, and the relative standard deviation (RSD) of the nutrient with the smallest proportion in the formula is less than 5%, and the mixing uniformity is good, which ensures that the product has effective nutrients and has Excellent efficacy. Description of the drawings

[0019] Figure 1 Effects of different sample groups on fasting blood glucose in hyperglycemia model rats.

[0020] Figure 2 Effects of different sample groups on fasting blood glucose in hyperglycemic population.

[0021] Figure 3 Effects of different sample groups on blood glucose 1 hour after meal in people with hyperglycemia. DETAILED DESCRIPTION

[0022] Comparative Example 1:

[0023] 1. Remove the outer packaging of skim milk powder, desalted whey powder, xylitol, concentrated whey protein, isomaltooligosaccharide, vitamin composition and mineral composition, sterilize them through a large bag tunnel sterilizer and a transfer window, and set them aside.

[0024] 2. Sift 5 portions of skimmed milk powder through an oscillating sieve and suck it into a weighing tank via a vacuum feeder for later use.

[0025] 3 Weigh 0.075 parts of vitamin composition, 0.14 parts of mineral composition and 2.5 parts of skim milk powder, pass through a 30-50 mesh sieve, and suck them into a 0.38m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (gas pressure 0.5 MPa, flow rate 800 L / h, temperature 25°C), the premixing time is 4 minutes, and mixed powder I is obtained. The mixed powder I is transported to a weighing tank by nitrogen positive pressure for use.

[0026] 4. Sift 2.5 parts of skim milk powder, 9 parts of desalted whey powder, 1.75 parts of concentrated whey protein, 3.035 parts of xylitol and 1 part of isomaltooligosaccharide through an oscillating sieve and suck them into a weighing tank by a vacuum feeder for later use.

[0027] 5 Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (body pressure 0.5 MPa, flow rate 800 L / h, temperature 25°C), and the total mixing time is 10 minutes to obtain a total mixed powder.

[0028] 6 The obtained total mixed powder was packaged by a metal detector (metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, non-iron φ≥1mm) and then by a fully automatic packaging machine (quantitative packaging and heat sealing treatment are carried out by the fully automatic packaging machine under the gas mediation of a flow rate of 800L / h and a pressure of 0.8MPa, the controlled filling amount is 25±0.2g / bag, and the quantitative packaging accuracy is more than 99.9%) to obtain the elderly modulated milk powder (i.e., modulated milk powder sample group A) that assists in lowering blood sugar. Note: The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the excellent product rate is ≥99%. Example 1

[0029] 1. Remove the outer packaging of skim milk powder, desalted whey powder, xylitol, concentrated whey protein, mulberry leaf extract, barley malt powder, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder, isomaltooligosaccharide, Lactobacillus rhamnosus JYLR-005, oat bran, vitamin composition and mineral composition, sterilize them through a large bag tunnel sterilizer and a transfer window, and set them aside.

[0030] 2. Sift 5 portions of skimmed milk powder through an oscillating sieve and suck it into a weighing tank via a vacuum feeder for later use.

[0031] 3 Weigh 0.25 parts of mulberry leaf extract, 0.17 parts of barley malt powder, 0.17 parts of white kidney bean powder, 0.01 parts of L-arabinose, 0.02 parts of lotus leaf powder, 0.02 parts of ginkgo powder, 0.02 parts of Lactobacillus rhamnosus JYLR-005, 0.1 parts of oat bran, 0.075 parts of vitamin composition and 0.14 parts of mineral composition, pass through a 30-50 mesh sieve, and suck to 0.38m by a vacuum feeder. 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (gas pressure 0.4 MPa, flow rate 300 L / h, temperature 25°C), the premixing time is 3 min, and mixed powder I is obtained. The mixed powder I is transported to a weighing tank by nitrogen positive pressure for standby use.

[0032] 4. Sift 5 parts of skim milk powder, 9 parts of desalted whey powder, 1.75 parts of concentrated whey protein, 2.275 parts of xylitol and 1 part of isomaltooligosaccharide through an oscillating sieve and suck them into a weighing tank by a vacuum feeder for later use.

[0033] 5 Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (body pressure 0.4 MPa, flow rate 300 L / h, temperature 25°C), and the total mixing time is 5 minutes to obtain a total mixed powder.

[0034] 6 The obtained total mixed powder was packaged by a metal detector (metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, non-iron φ≥1mm) and then by a fully automatic packaging machine (quantitative packaging and heat sealing treatment are carried out by a fully automatic packaging machine under the gas mediation of a flow rate of 500L / h and a pressure of 0.6MPa, the controlled filling amount is 25±0.2g / bag, and the quantitative packaging accuracy is above 99.9%) to obtain the elderly modulated milk powder (i.e., modulated milk powder sample group B) that assists in lowering blood sugar. Note: The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the rate of excellent products is ≥99%. Example 2

[0035] 1. Remove the outer packaging of skim milk powder, desalted whey powder, xylitol, concentrated whey protein, mulberry leaf extract, barley malt powder, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder, isomaltooligosaccharide, Lactobacillus rhamnosus JYLR-005, oat bran, vitamin composition and mineral composition, sterilize them through a large bag tunnel sterilizer and a transfer window, and set them aside.

[0036] 2. Sift 4.85 portions of skimmed milk powder through an oscillating sieve and suck it into a weighing tank via a vacuum feeder for later use.

[0037] 3 Weigh 0.75 parts of mulberry leaf extract, 0.5 parts of barley malt powder, 0.5 parts of white kidney bean powder, 0.03 parts of L-arabinose, 0.03 parts of lotus leaf powder, 0.05 parts of ginkgo powder, 0.02 parts of Lactobacillus rhamnosus JYLR-005, 0.2 parts of oat bran, 0.075 parts of vitamin composition and 0.14 parts of mineral composition, pass through a 30-50 mesh sieve, and suck to 0.38m by a vacuum feeder. 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (gas pressure 0.5 MPa, flow rate 800 L / h, temperature 25°C), the premixing time is 4 minutes, and mixed powder I is obtained. The mixed powder I is transported to a weighing tank by nitrogen positive pressure for use.

[0038] 4.85 parts of skim milk powder, 8.2 parts of desalted whey powder, 2 parts of concentrated whey protein, 1.305 parts of xylitol and 1.5 parts of isomaltooligosaccharide are sieved through an oscillating sieve and then sucked into a weighing tank by a vacuum feeder for later use.

[0039] 5 Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (body pressure 0.5 MPa, flow rate 800 L / h, temperature 25°C), and the total mixing time is 10 minutes to obtain a total mixed powder.

[0040] 6 The obtained total mixed powder was packaged by a metal detector (metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, non-iron φ≥1mm) and then by a fully automatic packaging machine (quantitative packaging and heat sealing treatment are carried out by the fully automatic packaging machine under the gas mediation of a flow rate of 800L / h and a pressure of 0.8MPa, the controlled filling amount is 25±0.2g / bag, and the quantitative packaging accuracy is more than 99.9%) to obtain the elderly modulated milk powder (i.e., modulated milk powder sample group C) that assists in lowering blood sugar. Note: The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the rate of excellent products is ≥99%. Example 3

[0041] 1. Remove the outer packaging of skim milk powder, desalted whey powder, xylitol, concentrated whey protein, mulberry leaf extract, barley malt powder, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder, isomaltooligosaccharide, Lactobacillus rhamnosus JYLR-005, oat bran, vitamin composition and mineral composition, sterilize them through a large bag tunnel sterilizer and a transfer window, and set them aside.

[0042] 2. Sift 4.5 portions of skimmed milk powder through an oscillating sieve and suck it into a weighing tank via a vacuum feeder for later use.

[0043] 3 Weigh 1 part of mulberry leaf extract, 0.75 parts of barley malt powder, 0.75 parts of white kidney bean powder, 0.05 parts of L-arabinose, 0.05 parts of lotus leaf powder, 0.1 parts of ginkgo powder, 0.02 parts of Lactobacillus rhamnosus JYLR-005, 0.2 parts of oat bran, 0.075 parts of vitamin composition and 0.14 parts of mineral composition, pass through a 30-50 mesh sieve, and suck to 0.38m by a vacuum feeder. 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (gas pressure 0.6 MPa, flow rate 1000 L / h, temperature 25°C), the premixing time is 5 min, and mixed powder I is obtained. The mixed powder I is transported to a weighing tank by nitrogen positive pressure for standby use.

[0044] 4.5 parts of skim milk powder, 7.8 parts of desalted whey powder, 2.7 parts of concentrated whey protein, 0.365 parts of xylitol and 2 parts of isomaltooligosaccharide are sieved through an oscillating sieve and sucked into a weighing tank by a vacuum feeder for later use.

[0045] 5 Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (body pressure 0.6 MPa, flow rate 1000 L / h, temperature 25°C), and the total mixing time is 15 minutes to obtain a total mixed powder.

[0046] 6 The obtained total mixed powder was packaged by a metal detector (metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, non-iron φ≥1mm) and then by a fully automatic packaging machine (quantitative packaging and heat sealing treatment are carried out by the fully automatic packaging machine under the gas mediation of a flow rate of 1000L / h and a pressure of 1.0MPa, the controlled filling amount is 25±0.2g / bag, and the quantitative packaging accuracy is more than 99.9%) to obtain the elderly modulated milk powder (i.e., modulated milk powder sample group D) that assists in lowering blood sugar. Note: The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the excellent product rate is ≥99%.

[0047] Experimental Example 1: Comparison of mixing effects between three-dimensional mixing process and pneumatic mixing process

[0048] 1 Three-dimensional mixing process: 0.075 parts of the vitamin composition, 0.14 parts of the mineral composition, 0.03 parts of L-arabinose, 0.05 parts of ginkgo powder, 0.03 parts of lotus leaf powder, 0.02 parts of Lactobacillus rhamnosus JYLR-005 and an equal amount of skim milk powder were mixed for the first time for 5 minutes, and after mixing evenly, a total mixture I was obtained; the total mixture I was mixed with an equal amount of skim milk powder for a second time for 5 minutes, and after mixing evenly, a total mixture II was obtained. ; Mix the total mixture II, white kidney bean powder, 0.5 parts of barley malt powder, 0.2 parts of oat bran, 0.75 parts of mulberry leaf extract and an equal amount of skim milk powder for a third time, mix for 5 minutes, and mix evenly to obtain the total mixture III; mix the total mixture III, 8.2 parts of desalted whey powder, 1.5 parts of isomaltooligosaccharide, 1.305 parts of xylitol, 2 parts of concentrated whey protein and the remaining skim milk powder for a total mixing time of about 30 minutes to obtain the total mixed powder.

[0049] 2 Pneumatic mixing process: 2 4.85 parts of skim milk powder are sieved through an oscillating sieve and then sucked into a weighing tank by a vacuum feeder for standby use; 0.75 parts of mulberry leaf extract, 0.5 parts of barley malt powder, 0.5 parts of white kidney bean powder, 0.03 parts of L-arabinose, 0.03 parts of lotus leaf powder, 0.05 parts of ginkgo powder, 0.02 parts of Lactobacillus rhamnosus JYLR-005, 0.2 parts of oat bran, 0.075 parts of vitamin composition and 0.14 parts of mineral composition are weighed, and after passing through a 30-50 mesh sieve, they are sucked into a 0.38m3 pneumatic mixing tank by a vacuum feeder. Mix under nitrogen (gas pressure 0.5MPa, flow rate 800L / h, temperature 25℃), premix time is 5min, and mixed powder I is obtained. Mixed powder I is transported to a weighing tank by nitrogen positive pressure for standby use; 4.85 parts of skim milk powder, 8.2 parts of desalted whey powder, 2 parts of concentrated whey protein, 1.305 parts of xylitol and 1.5 parts of oligomaltose are sieved through an oscillating sieve and sucked into a weighing tank by a vacuum feeder for standby use; after checking the weight and confirming that the feeding amount is consistent with the formula amount, the materials in the weighing tank are sucked into a 1.2m 3 In a pneumatic mixing tank, mixing is carried out under the mediation of nitrogen (body pressure 0.5 MPa, flow rate 800 L / h, temperature 25°C), and the total mixing time is 15 minutes to obtain a total mixed powder.

[0050] 3 Verification of mixing uniformity: A nine-point sampling method was used, with three points at the top, middle and bottom, to determine the content of vitamin D, a characteristic ingredient in the mixed powders of the two mixing processes mentioned above, and a verification test of mixing uniformity was conducted. The results are shown in Table 1.

[0051] Table 1 Determination of vitamin D content in mixed powder (content per 25g, μg)

[0052]

[0053] Based on the above, the total number of mixing times of the three-dimensional mixing process is 4 times, the total mixing time is 45 minutes, and the RSD value is 2.15%. The total number of mixing times of the pneumatic mixing process is 2 times, the total mixing time is 20 minutes, and the RSD value is 1.78%. Compared with the two mixing processes, the pneumatic mixing process has the characteristics of fewer total mixing times, shorter time, smaller RSD value, and more uniform mixing. Therefore, the use of pneumatic mixing technology in the production process can minimize the errors caused by human factors, and can also greatly reduce production energy consumption, saving costs for the company's development.

[0054] Experimental Example 2: Nutritional evaluation

[0055] The physical and chemical indicators such as nutritional components of the modified milk powder sample groups A to D and similar commercial milk powder were determined. The following experiments were repeated 3 times to ensure the accuracy of the experimental values. The data are expressed as mean ± standard deviation. The determination results are shown in Table 2.

[0056] Table 2 Summary of nutritional components of different formula milk powders

[0057] Item / 100g Group A Group B Group C Group D Similar milk powder on the market Protein, g 20.23±0.12 20.67±0.32 21.13±0.59 22.22±1.00 19.14±0.41 Fat, g 12.85±0.89 12.96±0.69 13.25±0.26 13.81±0.90 18.17±0.96 Carbohydrate, g 52.10±0.62 49.80±0.63 48.82±0.54 47.38±1.31 60.04±0.51 Dietary fiber, g 0 6.13±0.41 6.3±0.12 6.39±0.85 5.57±0.91 Sodium, mg 301.01±0.24 300.04±0.54 300.08±0.48 300.12±1.26 320.05±0.68 Taurine, mg 38.13±0.32 38.05±0.69 38.04±0.10 38.07±0.61 - Vitamin A, μgRE 432.04±1.67 430.04±0.63 440.01±0.11 450.09±0.90 410.05±0.62 Vitamin C, mg 51.02±0.88 50.04±0.61 50.06±0.82 50.08±072 30.014±0.16 Vitamin D, μg 7.21±0.54 7.14±0.63 7.22±0.26 7.64±1.63 7.11±1.53 Vitamin E, mg α-TE 11.37±0.32 11.08±0.12 11.95±0.77 12.07±0.61 10.56±0.79 Folic acid, μg 342.04±1.64 340.04±0.67 340.06±0.77 340.11±1.15 - Calcium, mg 1001.01±0.08 1000.11±0.18 1001.09±0.14 1002.15±1.75 800.01±0.35 Iron, mg 10.71±0.60 10.04±0.60 10.06±0.08 10.09±0.81 10.10±0.62 Zinc, mg 4.24±0.52 4.54±0.54 4.54±0.54 4.60±0.95 3.55±0.62 Selenium, μg 20.16±0.94 20.06±0.98 20.06±0.89 20.07±0.61 - (Note: The nutrient content of sample groups A to D provided by the present invention complies with the use standard of GB 14880-2012 National Food Safety Standard Food Nutrient Fortifiers and the recommended intake of nutrients for the elderly in the Chinese Dietary Guidelines; the experimental analysis was performed using IBM SPSS Statistics 20 software for significance analysis.) From Table 2, the nutrient contents of sample groups A~D are as follows: the protein content is greater than 20g / 100g, and the maximum value is 13.86% higher than that of similar commercial milk powder; the calcium content is greater than 1000mg / 100g, and the maximum value is 20.17% higher than that of similar commercial milk powder; the dietary fiber content is greater than 6g / 100g, and the maximum value is 12.83% higher than that of similar commercial milk powder; the fat content is less than 14g / 100g, and similar commercial milk powder is 24% higher than its maximum value; in addition, compared with similar commercial milk powder, taurine for enhancing vitality, folic acid for preventing anemia and selenium for preventing cardiovascular and cerebrovascular diseases are additionally added.

[0058] Therefore, it is proved that the elderly formula milk powder for assisting in lowering blood sugar provided by the present invention is rich in nutrition and more suitable for consumption by elderly people with abnormal blood sugar levels.

[0059] Experimental Example 3: Evaluation of the auxiliary blood sugar lowering effect

[0060] The auxiliary blood sugar lowering stability effect test in this experiment was conducted with reference to the auxiliary blood sugar lowering function in the National Food and Drug Administration

[2012] No. 107 document; the experimental analysis was performed using IBM SPSS Statistics 20 software for significance analysis.

[0061] 1. Hypoglycemic test drink test in hyperglycemic rats 40 male rats with insulin resistance and glucose metabolism disorder induced by alloxan were selected as experimental animals. The rats were evenly divided into four groups, 10 in each group. Under normal diet, the test samples diluted 30 times were given to sample groups A, B, C and D, respectively. The feeding dose was 200 mg / kg, and the rats were gavaged three times a day for 4 consecutive weeks. The average fasting blood glucose of the rats was measured every week. The results are shown in the figure. Figure 1 shown.

[0062] Depend on Figure 1The results showed that after the experiment, the average fasting blood glucose values ​​of the four groups of hyperglycemic model rats all decreased to varying degrees. The blood glucose reduction rates of sample group D, sample group C, sample group B, and sample group A were 73.53%, 67.66%, 30.26%, and 9.41%, respectively, indicating that sample group D had the best hypoglycemic effect, sample group C was better, sample group B was second, and sample group A was the worst. Compared with sample group A, the average fasting blood glucose values ​​of rats in sample groups D and sample groups C were significantly lower ( P <0. 01) is lower than sample group A, which can further prove that the hypoglycemic functional composition and the dietary fiber composition provided by the present invention synergize with each other and have the effect of lowering blood sugar.

[0063] 2. Trial of hypoglycemic medication for people with high blood sugar levels This trial publicly recruited 40 elderly subjects over 60 years old, half of whom were male and half were female, with mild to moderate diabetes and fasting blood sugar between 8.0 and 9.5 mmol / L, and they were willing to participate. The subjects were randomly divided into 4 groups, half of whom were male and half were female, and were given sample A, sample B, sample C, and sample D respectively. They were asked to mix 25g of the corresponding elderly formula milk powder to help lower blood sugar with 100mL of warm water before breakfast, lunch, and dinner every day, and drink it for 30 days. They were required to reduce the use of medication by half, eat a light and nutritious diet, and measure fasting blood sugar and 1h after meals every 15 days. The blood sugar test was performed using the glucose oxidase method. The test samples were given for 1 month, and the results were as follows Figure 2~3 shown.

[0064] Depend on Figure 2~3 It can be seen that sample groups B, C, and D can reduce the blood sugar level of patients with moderate to mild diabetes. With the increase of the content of dietary fiber and the hypoglycemic functional composition, the fasting blood sugar level is significantly (p < 0.05) reduced, wherein the fasting blood sugar level decrease rate of sample group D is 10.77%, and the blood sugar level decrease rate 1 hour after the meal is 14.60%, the fasting blood sugar level decrease rate of sample group C is 7.99%, and the blood sugar level decrease rate 1 hour after the meal is 12.51%, the fasting blood sugar level decrease rate of sample group B is 4.73%, and the blood sugar level decrease rate 1 hour after the meal is 5.89%, the fasting blood sugar level decrease rate of sample group A is 0.79%, and the blood sugar level decrease rate 1 hour after the meal is 2.62%, which further proves that after the elderly with moderate to mild diabetes have halved their medication, drinking the elderly formula milk powder that assists in lowering blood sugar levels can play an auxiliary role in lowering blood sugar levels, and the added amount of dietary fiber and the hypoglycemic functional composition affects the hypoglycemic effect, that is, the degree of blood sugar reduction increases with the increase of the content of dietary fiber and the hypoglycemic functional composition.

Claims

1. A formula milk powder for the elderly that assists in lowering blood sugar levels, comprising the following components and weights: 1-25 parts of a milk-based composition (skim milk powder, desalted whey powder and concentrated whey protein), 0.01-6 parts of a blood sugar-lowering functional composition (mulberry leaf extract, barley malt powder, white kidney bean powder, L-arabinose, lotus leaf powder, ginkgo powder, oligomaltosaccharide and Lactobacillus rhamnosus JYLR-005), 0.1-1 parts of a dietary fiber composition (oat bran), 0.01-0.075 parts of a vitamin composition (taurine, retinyl acetate, sodium L-ascorbate, cholecalciferol, dl-α-tocopherol acetate, folic acid), and 0.14-0.28 parts of a mineral composition (ferric pyrophosphate, zinc citrate, sodium selenite, calcium carbonate), and xylitol as a supplement.

2. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels, characterized in that: The following steps are involved: Step 1: Remove the outer packaging of the milk-based composition, the hypoglycemic functional composition, the vitamin composition, and the mineral composition, sterilize them in a large bag tunnel sterilizer and a transfer window, and set them aside; Step 2: After the raw material with the largest proportion in the formula is sieved through an oscillating sieve, it is sucked into the weighing tank by a vacuum feeder according to half of its proportion in the formula as the bottom layer of the tank; Step 3: Weigh the raw and auxiliary materials at the end of the ingredient list until the total weight is one tenth of the total weight of the formula, pass through a 30-50 mesh sieve, and then be sucked to 0.38m by a vacuum feeder 3 In the pneumatic mixing tank, the mixture is mixed under the mediation of nitrogen to obtain mixed powder I. The mixed powder I is transported to the weighing tank by nitrogen positive pressure, and the backflush is turned on to move 0.38m 3 The remaining material in the pneumatic mixing tank is blown into the weighing tank as the middle layer of the tank; Step 4: The remaining raw and auxiliary materials except those in steps 2 and 3 are sieved through an oscillating sieve and sucked into a weighing tank by a vacuum feeder according to the formula amount as the top layer of the mixture; Step 5: Check the weight and confirm that the feeding amount is consistent with the formula amount. Then suck the material in the weighing tank to 1.2m 3 Mixing is performed in a pneumatic mixing tank to obtain a total mixed powder; Step 6: The obtained total mixed powder is subjected to metal detection and then packaged by a fully automatic packaging machine to obtain a modified milk powder for the elderly that assists in lowering blood sugar; The RSD relative standard deviation of nutrients in the product is <5%, the residual oxygen content is <0.25%, and the quality rate is ≥99%.

3. A formula milk powder for assisting in lowering blood sugar level in the elderly as claimed in claim 1, characterized in that: The hypoglycemic functional composition is a mixture of one or more of 0.25-1 part of mulberry leaf extract, 0.17-0.75 part of barley malt powder, 0.17-0.75 part of white kidney bean powder, 0.01-0.05 part of L-arabinose, 0.02-0.05 part of lotus leaf powder, 0.02-0.1 part of ginkgo powder, 1-2 parts of isomaltooligosaccharide and 0.01-1 part of Lactobacillus rhamnosus JYLR-005 in any proportion.

4. A formula milk powder for assisting in lowering blood sugar level in the elderly as claimed in claim 1, characterized in that: The milk-based composition is one or more of 9-10 parts of skim milk powder, 7-9 parts of desalted whey powder and 1-3 parts of concentrated whey protein, mixed in any proportion.

5. A formula milk powder for assisting in lowering blood sugar level in the elderly as claimed in claim 1, characterized in that: The protein content is not less than 20g / 100g, the calcium content is not less than 1000mg / 100g, and the amount of Lactobacillus rhamnosus JYLR-005 added is not less than 10 8 CFU / g.

6. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 2, characterized in that: The mixing conditions in steps 2 to 5 are: nitrogen mixed sample conditions: gas pressure 0.4-0.6MPa, flow rate 300-1000L / h, temperature 20-25°C.

7. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 2, characterized in that: The premixing time in step 3 is 3-5 minutes, and the total mixing time in step 5 is 5-15 minutes.

8. A method for preparing a formula milk powder for the elderly that assists in lowering blood sugar levels as claimed in claim 2, characterized in that: In step 6, the metal detection conditions are iron φ≥0.8mm, stainless steel φ≥1.25mm, and non-ferrous φ≥1mm; the quantitative packaging and heat sealing treatment are carried out by a fully automatic packaging machine under the gas mediation of a flow rate of 500-1000L / h and a pressure of 0.6-1.0MPa, the filling amount is controlled to be 25±0.2g / bag, and the quantitative packaging accuracy is above 99.9% to obtain the final product.

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